Title: “Adjacent Nontumor Mucosa: The Overlooked Frontier in Colorectal Cancer Prognostication.” This is an interesting article that offers an interpretation and extension of Yeetal's study. It accurately summarizes the original research and provides important discussion on tumor immunology and clinical translation. The authors stress the importance of the "adjacent nontumor mucosa" as an independent immune prognostic compartment. The authors may consider changing the title to a more impactful one, e.g.,” Beyond the Margin: Adjacent Nontumor Mucosa as a Determinant of Colorectal Cancer Outcome.”