Sun YT, Zhou F, Zheng HX, Xiao JD. Clinical efficacy and mechanism of Bletilla striata and Chinese herbal compounds in treatment of peptic ulcer. World J Gastroenterol 2025; 31(30): 110145 [PMID: 40904885 DOI: 10.3748/wjg.v31.i30.110145]
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03769692
Submitted on:
August 15, 2025, 18:53
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Reader Comments:
This paper provides a detailed review of the clinical efficacy and mechanisms of Bletilla striata in treating peptic ulcers (PUs). The study explores both monotherapy and compound formulations, highlighting its potential in promoting ulcer healing, reducing inflammation, and improving gastric mucosal repair. The inclusion of experimental data and clinical studies demonstrates Bletilla striata's therapeutic efficacy, particularly in combination with conventional treatments like PPIs and antibiotics for Helicobacter pylori eradication. The clinical relevance of this paper is high, especially for those working in gastroenterology and traditional Chinese medicine. It brings attention to an herbal remedy with promising effects on PUs, a common and often recurring condition. However, the review also suggests that more rigorous clinical trials and studies focusing on the long-term safety and efficacy of Bletilla striata in PU treatment are needed.
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