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Hakoda A, Takayama K, Sasaki S, Mori Y, Tanaka H, Sugawara N, Iwatsubo T, Ota K, Nishikawa H. A case of gastrolithiasis produced by a 5-day diet. DEN OPEN 2025; 5:e70012. [PMID: 39286005 PMCID: PMC11403761 DOI: 10.1002/deo2.70012] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 07/15/2024] [Revised: 08/28/2024] [Accepted: 09/01/2024] [Indexed: 09/19/2024]
Abstract
A 55-year-old man with a history of distal gastrectomy was admitted to our hospital due to gastrointestinal bleeding from an anastomotic ulcer. After endoscopic hemostasis, his oral intake resumed after 1 day of fasting; however, he could not ingest food because of early satiety and nausea on the fifth day of oral intake resumption. Esophagogastroduodenoscopy was performed again to investigate the cause of anorexia and revealed a massive gastrolithiasis that was not observed in the previous esophagogastroduodenoscopy, which was diagnosed as the cause of his anorexia. Gastrolithiasis was treated with endoscopic removal the day after diagnosis, and the patient was discharged from the hospital after his symptoms resolved. Herein, we report the case of a patient with gastrolithiasis that developed and proliferated within 5 days.
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Affiliation(s)
- Akitoshi Hakoda
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
| | - Kazuki Takayama
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
| | - Shun Sasaki
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
| | - Yosuke Mori
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
| | - Hironiri Tanaka
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
| | - Noriaki Sugawara
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
| | - Taro Iwatsubo
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
| | - Kazuhiro Ota
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
| | - Hiroki Nishikawa
- Second Department of Internal Medicine Osaka Medical and Pharmaceutical University Osaka Japan
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Capristán-Díaz V, de Sol P, González González J, González Miyar R, Campos Del Portillo R. When anorexia nervosa complicates: Bezoar and gastroduodenal obstruction. ENDOCRINOL DIAB NUTR 2025; 72:50-51. [PMID: 39730244 DOI: 10.1016/j.endien.2024.12.002] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/10/2024] [Accepted: 08/08/2024] [Indexed: 12/29/2024]
Affiliation(s)
- Vanessa Capristán-Díaz
- Servicio de Endocrinología y Nutrición, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain.
| | - Pablo de Sol
- Servicio de Psiquiatría, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain
| | - Juan González González
- Servicio de Cirugía General y Digestiva, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain
| | - Rosalía González Miyar
- Servicio de Digestivo, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain
| | - Rocío Campos Del Portillo
- Servicio de Endocrinología y Nutrición, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain
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Kowazaki Y, Fukuda H, Sawano T, Okazaki M. A Case of Gastroliths Simultaneously Found in the Stomach and Small Intestine. Intern Med 2024; 63:3253-3254. [PMID: 38569901 PMCID: PMC11671184 DOI: 10.2169/internalmedicine.3514-24] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/16/2024] [Accepted: 02/15/2024] [Indexed: 04/05/2024] Open
Affiliation(s)
- Yuka Kowazaki
- Department of Gastroenterology, Jyoban Hospital, Tokiwa Foundation, Japan
| | - Hisashi Fukuda
- Department of Gastroenterology, Jyoban Hospital, Tokiwa Foundation, Japan
- Department of Medicine, Division of Gastroenterology, Jichi Medical University, Japan
| | - Toyoaki Sawano
- Department of Surgery, Jyoban Hospital, Tokiwa Foundation, Japan
| | - Masayuki Okazaki
- Department of Nephrology, Jyoban Hospital, Tokiwa Foundation, Japan
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Shrivastava RKP, Shrivastava A. Swallowed secrets - Plastic bezoar-induced gastric outlet obstruction in a 14-year-old girl: A case report. Int J Surg Case Rep 2024; 122:110075. [PMID: 39094318 PMCID: PMC11345920 DOI: 10.1016/j.ijscr.2024.110075] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/26/2024] [Revised: 07/16/2024] [Accepted: 07/22/2024] [Indexed: 08/04/2024] Open
Abstract
INTRODUCTION Gastric outlet obstruction (GOO) is a rare but serious condition that can arise from various etiologies, including foreign body ingestion. We present a unique case of GOO in a 14-year-old girl resulting from the accumulation of plastic materials, known as a plastic bezoar, due to pica behavior. CASE PRESENTATION A 14-year-old girl with a history of pica presented with symptoms suggestive of acute gastric obstruction. Imaging studies revealed the presence of a large foreign body extending from the stomach to the jejunum, consistent with a plastic bezoar. Despite attempts at endoscopic removal, surgical intervention was ultimately required due to the size and location of the bezoar. DISCUSSION This case underscores the challenges associated with diagnosing and managing gastric outlet obstruction secondary to plastic bezoar formation, particularly in pediatric patients with underlying pica behavior. The diagnostic workup involved a multidisciplinary approach, including imaging studies and endoscopic evaluation. Surgical intervention, although invasive, proved necessary for definitive treatment in this case. Postoperative care focused on monitoring for complications and addressing the underlying pica behavior through psychological intervention and support. CONCLUSION This case highlights the importance of early recognition, thorough diagnostic evaluation, and prompt intervention to prevent complications and ensure favorable outcomes. Collaborative efforts between medical and surgical teams are essential for the comprehensive management of such cases, emphasizing the need for tailored approaches to address both the physical and psychological aspects of care.
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Urlapu KS, Mantri N, Patel H, Lajara Hallal P, Chilimuri S, Diaz-Fuentes G. Severe Airway Obstruction Caused by Esophageal Bezoar with Coca-Cola and Creon (Pancrelipase) in a Patient with Underlying Achalasia: A Comprehensive Case Report. Case Rep Gastrointest Med 2024; 2024:2081040. [PMID: 39104748 PMCID: PMC11300067 DOI: 10.1155/2024/2081040] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/08/2024] [Revised: 06/16/2024] [Accepted: 07/09/2024] [Indexed: 08/07/2024] Open
Abstract
Introduction The occurrence of acute respiratory failure as a result of esophageal bezoars is a rare phenomenon. We present a patient who failed initial endoscopic intervention. Successful resolution was achieved through a novel approach involving a combination of Creon and Coca-Cola. Subsequently, the patient was diagnosed with achalasia, a condition that potentially contributed to the formation of the esophageal bezoar. Case Description. An 82-year-old man presented with respiratory distress, necessitating endotracheal intubation for airway protection. A chest computed tomogram (CT) showed pneumonia and a distended esophagus compressing the trachea, raising the possibility of an esophageal food bolus. Endoscopy revealed a severely dilated esophagus containing a significant amount of food and a phytobezoar in the lower esophagus. He failed various endoscopic techniques to remove the obstruction. Given the patient's poor surgical candidacy, he was started in a thrice-daily regimen of Creon dissolved in 165 mL of Coca-Cola, over a 4-day period. A subsequent endoscopy revealed no discernible evidence of food or bezoar. The patient was weaned from mechanical ventilation. A high-resolution esophageal manometry identified type 1 achalasia. Conclusion Esophageal food impaction leading to respiratory failure is rare. Endoscopy remains the mainstay approach. Surgical interventions carry significant risks. This case emphasizes the potential for noninvasive management in patients with esophageal bezoars and also underscores the significance of contemplating esophageal pathologies when addressing cases of respiratory failure. The use of Coca-Cola and Creon emerges as a safe, effective, and cost-efficient treatment, providing a feasible option when endoscopy proves unsuccessful before considering more aggressive interventions.
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Affiliation(s)
- Kinnera Sahithi Urlapu
- Division of Pulmonary and Critical CareDepartment of MedicineBronx Care Health SystemAffiliated with Icahn School of Medicine at Mount Sinai, New York, Bronx, USA
| | - Nikhitha Mantri
- Division of GastroenterologyDepartment of MedicineBronx Care Health SystemAffiliated with Icahn School of Medicine at Mount Sinai, New York, Bronx, USA
| | - Harish Patel
- Division of GastroenterologyDepartment of MedicineBronx Care Health SystemAffiliated with Icahn School of Medicine at Mount Sinai, New York, Bronx, USA
| | - Priscilla Lajara Hallal
- Department of MedicineBronx Care Health SystemAffiliated with Icahn School of Medicine at Mount Sinai, New York, Bronx, USA
| | - Sridhar Chilimuri
- Division of GastroenterologyDepartment of MedicineBronx Care Health SystemAffiliated with Icahn School of Medicine at Mount Sinai, New York, Bronx, USA
| | - Gilda Diaz-Fuentes
- Division of Pulmonary and Critical CareDepartment of MedicineBronx Care Health SystemAffiliated with Icahn School of Medicine at Mount Sinai, New York, Bronx, USA
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Esfandiary Rad AM, Malekzadeh MM. Troublesome Weight Loss: A Case Report of Large Gastric Phytobezoar. Middle East J Dig Dis 2024; 16:193-195. [PMID: 39386333 PMCID: PMC11459279 DOI: 10.34172/mejdd.2024.390] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 04/04/2024] [Accepted: 06/20/2024] [Indexed: 10/12/2024] Open
Abstract
Gastric bezoar is a very rare clinical condition and hard to treat. Phytobezoars are one of the most common types of bezoars, which happens with the consumption of indigestible fibers. In this report, we presented an elderly man with gastric phytobezoar who presented with peptic ulcer and was treated successfully with proton pump inhibitor (PPI) and Coca-Cola. Surveillance endoscopy showed a completely healed ulcer. It was shown that cautious use of Coca-Cola can be helpful and safe in treating concomitant phytobezoar and gastric ulcers. To the best of our knowledge, this is the first report of phytobezoar from Iran, which was treated with cola.
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Delgado Galan M, Rabago LR. Has Coca-Cola treatment become the first-line therapy for gastric bezoars, both in general and specifically for western countries? World J Gastrointest Endosc 2024; 16:237-243. [PMID: 38813574 PMCID: PMC11130549 DOI: 10.4253/wjge.v16.i5.237] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/19/2024] [Revised: 04/10/2024] [Accepted: 04/29/2024] [Indexed: 05/14/2024] Open
Abstract
Phytobezoars is a rare disease and less common in Western countries. The stomach is the primary site for these formations, and endoscopic treatment involving fragmentation and extraction has traditionally been the most effective approach. However, medical treatments using enzymatic and chemical agents, such as cellulase and Coca-Cola, aimed at dissolving the bezoars, have also been utilized, showing varying degrees of resolution success. Notably, the oral dissolution treatment with Coca-Cola has emerged as a promising, simpler, and more cost-effective method. The study by Liu et al represents an important step in clinical research on this topic, despite some limitations that need addressing for a more comprehensive understanding of its findings. Key considerations for future research include sample size calculation, endoscopic procedure details, outpatient vs. inpatient treatment, and detailed cost calculations. The study's exclusions, such as patients with upper gastric surgery, phytobezoars older than 14 d, and cases of gastroparesis, limit its applicability to broader populations, especially in Western countries. Given the promising outcomes of the Coca-Cola treatment, it's advocated as a first-line therapy for phytobezoars. Nonetheless, further research is essential to overcome these limitations. However special situations such as perforation or small bowel obstruction will require surgical treatment.
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Affiliation(s)
| | - Luis Ramon Rabago
- Department of Gastroenterology, Hospital San Rafael, Madrid 28016, Spain
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Liu FG, Meng DF, Shen X, Meng D, Liu Y, Zhang LY. Coca-Cola consumption vs fragmentation in the management of patients with phytobezoars: A prospective randomized controlled trial. World J Gastrointest Endosc 2024; 16:83-90. [PMID: 38464817 PMCID: PMC10921151 DOI: 10.4253/wjge.v16.i2.83] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/28/2023] [Revised: 01/04/2024] [Accepted: 01/16/2024] [Indexed: 01/31/2024] Open
Abstract
BACKGROUND Gastric phytobezoars (GPBs) are very common in northern China. Combined therapy involving carbonated beverage consumption and endoscopic lithotripsy has been shown to be effective and safe. Existing studies on this subject are often case reports highlighting the successful dissolution of phytobezoars through Coca-Cola consumption. Consequently, large-scale prospective investigations in this domain remain scarce. Therefore, we conducted a randomized controlled trial to examine the effects of Coca-Cola consumption on GPBs. AIM To evaluate the impact of Coca-Cola on GPBs, including the dissolution rate, medical expenses, ulcer rate, and operation time. METHODS A total of 160 consecutive patients diagnosed with GPBs were allocated into two groups (a control group and an intervention group) through computer-generated randomization. Patients in the intervention group received a Coca-Cola-based regimen (Coca-Cola 2000-4000 mL per day for 7 d), while those in the control group underwent emergency fragmentation. RESULTS Complete dissolution of GPBs was achieved in 100% of the patients in the intervention group. The disparity in expenses between the control group and intervention group (t = 25.791, P = 0.000) was statistically significant, and the difference in gastric ulcer occurrence between the control group and intervention group (χ2 = 6.181, P = 0.013) was also statistically significant. CONCLUSION Timely ingestion of Coca-Cola yields significant benefits, including a complete dissolution rate of 100%, a low incidence of gastric ulcers, no need for fragmentation and reduced expenses.
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Affiliation(s)
- Fu-Guo Liu
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - De-Feng Meng
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - Xia Shen
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - Dan Meng
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - Ying Liu
- Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
| | - Ling-Yun Zhang
- Endoscopy Center, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
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Riaz M, Akbar I, Hassan RE, Ahmad W, Khan H, Khan AU, Khan MH, Shah SS, Tahir A, Tanveer S. Effect of Coca-Cola on the Dissolution of Persimmon-Related Phytobezoar in a Tertiary Care Hospital. Cureus 2024; 16:e54420. [PMID: 38510864 PMCID: PMC10951130 DOI: 10.7759/cureus.54420] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 02/18/2024] [Indexed: 03/22/2024] Open
Abstract
Introduction Bezoars, masses of indigestible foreign bodies formed in the gastrointestinal tract, pose challenges in their management. Phytobezoars are particularly problematic due to their difficult diagnosis and resilience towards treatment. Recently, Coca-Cola has emerged as a potential solution due to its acidic composition and mucolytic properties. However, existing evidence is limited, highlighting the need for comprehensive studies. This research explores the efficacy of Coca-Cola in dissolving persimmon-related phytobezoars, aiming to contribute valuable insights to non-invasive treatment options. Material and methods Conducted as a descriptive case series, this study employed gastric cola lavage using non-probability purposive sampling. Patients aged 18-70 with persimmon-related phytobezoars were included. Two nasogastric tubes were inserted for cola lavage over 12 hours, utilizing three liters of cola until the disappearance of symptoms. When the bezoar disappeared, it was considered as complete success to the treatment. Results Out of 31 patients, 45.2% were male and 54.8% were female, with a mean age of 56.77 ± 9.01 years. Efficacy was noted in 54.8% of cases. Age less than 50 and no history of diabetes mellitus were associated with higher chances of treatment success (p-value ≤0.05). Conclusion Ingestion of Coca-Cola was highly effective, safe, and reliable for the dissolution of persimmon-related phytobezoars, as the frequency of efficacy was high in our study. Coca-Cola ingestion is a non-invasive and cost-effective mode of phytobezoar dissolution that should be taken as a first-line initial treatment option to attain desired outcomes.
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Affiliation(s)
- Maryam Riaz
- Surgery, Ayub Teaching Hospital, Abbottabad, PAK
| | - Ismail Akbar
- Surgery, Ayub Teaching Hospital, Abbottabad, PAK
| | - Rao E Hassan
- Orthopedics and Trauma, Khyber Teaching Hospital-Medical Training Institute (MTI), Peshawar, PAK
| | - Waheed Ahmad
- General Surgery, Hayatabad Medical Complex-Medical Training Institute (MTI), Peshawar, PAK
| | - Hassamullah Khan
- General Surgery, Hayatabad Medical Complex-Medical Training Institute (MTI), Peshawar, PAK
| | | | | | - Syeda Sunaina Shah
- General Surgery, Hayatabad Medical Complex-Medical Training Institute (MTI), Peshawar, PAK
| | - Asna Tahir
- Ophthalmology, Khyber Teaching Hospital-Medical Training Institute (MTI), Peshawar, PAK
| | - Safina Tanveer
- Surgery, Khyber Teaching Hospital-Medical Training Institute (MTI), Peshawar, PAK
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Belhadj A, Touati MD, Othmane MRB, Khefacha F, Saidani A, Chebbi F. Revelation of Rapunzel syndrome: A rare case report of gastric trichobezoar-induced acute purulent peritonitis. Int J Surg Case Rep 2023; 111:108860. [PMID: 37748384 PMCID: PMC10520814 DOI: 10.1016/j.ijscr.2023.108860] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/15/2023] [Revised: 09/19/2023] [Accepted: 09/19/2023] [Indexed: 09/27/2023] Open
Abstract
INTRODUCTION AND IMPORTANCE The Rapunzel syndrome embodies an uncommon variation of trichobezoar, predominantly observed among individuals with a history of psychiatric conditions, trichotillomania, and trichophagia. This combination of factors predisposes to the eventual formation of gastric bezoars. Trichobezoars, infrequent gastric masses composed of hair, can lead to complications if left untreated. CASE REPORT A 19-year-old female hairdresser with a history of trichophagia sought medical attention due to abdominal pain and episodes of vomiting. With an elevated body temperature and abdominal rigidity, imaging revealed the presence of a trichobezoar, accompanied by pneumoperitoneum and intraperitoneal effusion. Urgent surgical intervention confirmed the diagnosis of generalized purulent acute peritonitis, triggered by a gastric perforation caused by a 20 cm trichobezoar with an extension into the duodenum, which defines the Rapunzel syndrome. Gastrotomy was performed to remove the trichobezoar, followed by thorough peritoneal lavage. CLINICAL DISCUSSION Trichobezoar is a rare condition that involves the abnormal accumulation of solid substances, particularly hair, within the stomach. Known as "Rapunzel syndrome," it can extend into the duodenum or jejunum. Commonly associated with emotional disorders, trichobezoar can lead to symptoms like epigastric discomfort, vomiting, and weight loss. Diagnosis is through endoscopy, and treatments include fluid intake, endoscopic extraction, chemical dissolution, and surgical removal. Surgical intervention is often preferred, with laparoscopic approaches considered. Psychiatric management is often required for patients. CONCLUSION This case underscores the uncommon Rapunzel syndrome presentation, emphasizing timely surgical measures and multidisciplinary care for trichobezoars causing acute peritonitis.
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Affiliation(s)
- Anis Belhadj
- General Surgery Department, Mahmoud El Matri Hospital, V59M+628 Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, Rue de la Faculté de Médecine, R534+F9H Tunis, Tunisia
| | - Med Dheker Touati
- General Surgery Department, Mahmoud El Matri Hospital, V59M+628 Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, Rue de la Faculté de Médecine, R534+F9H Tunis, Tunisia.
| | - Mohamed Raouf Ben Othmane
- General Surgery Department, Mahmoud El Matri Hospital, V59M+628 Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, Rue de la Faculté de Médecine, R534+F9H Tunis, Tunisia
| | - Fahd Khefacha
- General Surgery Department, Mahmoud El Matri Hospital, V59M+628 Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, Rue de la Faculté de Médecine, R534+F9H Tunis, Tunisia
| | - Ahmed Saidani
- General Surgery Department, Mahmoud El Matri Hospital, V59M+628 Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, Rue de la Faculté de Médecine, R534+F9H Tunis, Tunisia
| | - Faouzi Chebbi
- General Surgery Department, Mahmoud El Matri Hospital, V59M+628 Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, Rue de la Faculté de Médecine, R534+F9H Tunis, Tunisia
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Shah D, Ali Q, Bernier K, Gutierrez VA, Harper L. Successful Dissolution of a Large Gastric Phytobezoar Through Nonsurgical and Nonendoscopic Fragmentation. ACG Case Rep J 2023; 10:e01141. [PMID: 37753104 PMCID: PMC10519568 DOI: 10.14309/crj.0000000000001141] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/22/2022] [Accepted: 08/03/2023] [Indexed: 09/28/2023] Open
Abstract
A phytobezoar is the result of poorly digestible vegetable matter that accumulates in the gastrointestinal tract often forming a hard mass in the stomach. We present a case of a phytobezoar in a patient without predisposing risk factors, resulting in significant stomach distension initially believed to require high-risk surgical intervention but which ultimately resolved after 3 days of conservative treatment with prokinetic agents. The patient was discharged uneventfully and was recommended a low-fiber diet indefinitely while undergoing further workup for motility disorders.
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Affiliation(s)
- Divya Shah
- University of Arizona College of Medicine, Phoenix, AZ
| | - Qumber Ali
- University of Arizona College of Medicine, Phoenix, AZ
| | | | | | - Lise Harper
- University of Arizona College of Medicine, Phoenix, AZ
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Kosmidis CS, Mystakidou CM, Varsamis N, Koulouris C, Sevva C, Papadopoulou K, Michael C, Katsios NI, Theodorou V, Miltiadous P, Papadopoulos K, Vlassopoulos K, Zarampouka K, Mantalovas S. Phytobezoar-Induced Mechanical Ileus and Incipient Intussusception: A Case Report. MEDICINA (KAUNAS, LITHUANIA) 2023; 59:1227. [PMID: 37512039 PMCID: PMC10383327 DOI: 10.3390/medicina59071227] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 05/09/2023] [Accepted: 06/26/2023] [Indexed: 07/30/2023]
Abstract
Phytobezoars constitute conglomerates of indigested plant fibers and are a rare cause of acute mechanical ileus. They exhibit an increased prevalence in the elderly population and people with specific predisposing conditions. Radiological imaging can often set a definitive diagnosis and dictate the optimal therapeutic approach, combined with the patient's clinical status. An 81-year-old male presented with deteriorating clinical symptoms of intestinal obstruction, and an exploratory laparotomy was performed following inconclusive radiological findings; multiple phytobezoars and incipient intussusception were revealed intraoperatively. A patient's medical history can often raise clinical suspicion of phytobezoars. However, a careful etiological investigation is imperative in all cases of mechanical ileus in advanced ages; early detection and dissolution of phytobezoars, when applicable, can reduce the need for surgical interventions.
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Affiliation(s)
- Christoforos S Kosmidis
- European Interbalkan Medical Center, 10 Asklipiou Street, 55535 Pylaia, Greece
- 3rd Surgical Department, University General Hospital of Thessaloniki "AHEPA", School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
| | - Chrysi Maria Mystakidou
- Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
| | - Nikolaos Varsamis
- European Interbalkan Medical Center, 10 Asklipiou Street, 55535 Pylaia, Greece
| | - Charilaos Koulouris
- European Interbalkan Medical Center, 10 Asklipiou Street, 55535 Pylaia, Greece
- 3rd Surgical Department, University General Hospital of Thessaloniki "AHEPA", School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
| | - Christina Sevva
- 3rd Surgical Department, University General Hospital of Thessaloniki "AHEPA", School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
| | - Konstantina Papadopoulou
- 1st Department of Internal Medicine, G. Papanikolaou General Hospital of Thessaloniki, 57010 Thessaloniki, Greece
| | - Christina Michael
- Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
| | - Nikolaos Iason Katsios
- Medical School, Faculty of Health Sciences, University of Ioannina, 45110 Ioannina, Greece
| | - Vasiliki Theodorou
- Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
| | - Petrina Miltiadous
- Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
| | - Konstantinos Papadopoulos
- 3rd Surgical Department, University General Hospital of Thessaloniki "AHEPA", School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
| | - Konstantinos Vlassopoulos
- Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
| | - Katerina Zarampouka
- Pathology Department, Aristotle University of Thessaloniki, AHEPA University Hospital, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
| | - Stylianos Mantalovas
- 3rd Surgical Department, University General Hospital of Thessaloniki "AHEPA", School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
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13
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A Manual Device Assists in Endoscopic Removal of Huge Gastric Phytobezoar. Indian J Surg 2022. [DOI: 10.1007/s12262-022-03576-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/07/2022] Open
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Malick A, Shen B. Endoscopic Treatment of Postoperative Bleeding, Bezoars, and Foreign Bodies. Gastrointest Endosc Clin N Am 2022; 32:829-843. [PMID: 36202519 DOI: 10.1016/j.giec.2022.05.008] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 02/04/2023]
Abstract
Altered gastrointestinal anatomy is common in patients with inflammatory bowel disease, particularly in those who underwent bowel surgery. Commonly performed surgeries are bowel resection and anastomosis and strictureplasty for Crohn's disease; and restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. The area of anastomosis and suture line is at the greatest risk for the development of postoperative bleeding. Altered bowel anatomy, especially the presence of strictures, strictureplasty, or structural or functional pouch outlet obstruction, puts these patients at risk for bezoar formation and foreign body retention, including video endoscopy capsule. This article will focus on postoperative bleeding, bezoar formation, and video capsule retention in patients with inflammatory bowel disease. Endoscopic management of these conditions is useful and is becoming an increasingly popular alternative to surgery.
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Affiliation(s)
- Alyyah Malick
- Department of Medicine, Columbia University Irving Medical Center-New York Presbyterian Hospital, 622 W 168th St, New York, NY 10032, USA.
| | - Bo Shen
- Center for Inflammatory Bowel Disease, Columbia University Irving Medical Center-NewYork Presbyterian Hospital, 161 Fort Washington Avenue, 8th Floor, New York, NY 10032, USA
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15
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Gastric Xylobezoar Treated with Continuous Enteral Coca-Cola® Infusion. Case Rep Pediatr 2022; 2022:7187356. [PMID: 36072305 PMCID: PMC9441401 DOI: 10.1155/2022/7187356] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/27/2022] [Accepted: 08/13/2022] [Indexed: 12/02/2022] Open
Abstract
Xylobezoar is a rare clinical condition in which undigested paper becomes trapped in the gastrointestinal tract causing varying degrees of gastrointestinal obstruction. This condition can be suspected in children with a history of gastric surgeries, decreased gastrointestinal motility, or pica. Xylobezoar presents with symptoms ranging from chronic abdominal pain to gastrointestinal perforation. Surgical intervention is often required as endoscopic removal is challenging and not always successful. Chemical dissolution has been shown to be effective in treating certain bezoars. Here, we report a case of a pediatric patient with xylobezoar who was successfully treated with continuous enteral Coca-Cola® infusion.
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16
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Huang P, Liu W. Gastric Phytobezoar Removed Endoscopically. Indian J Surg 2022. [DOI: 10.1007/s12262-022-03544-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/24/2022] Open
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17
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Gentile M, Vergara L, Schiavone V, Cestaro G, Sivero L. Harry Potter's Occlusion: Report of a Case of Pumpkin Seed Bezoar Rectal Impact. Front Surg 2022; 9:902701. [PMID: 35910475 PMCID: PMC9329672 DOI: 10.3389/fsurg.2022.902701] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/23/2022] [Accepted: 06/17/2022] [Indexed: 11/25/2022] Open
Abstract
Bezoar is a term from Arabic "bāzahr" or ultimately from Middle Persian "p'tzhl" (pādzahr, "bezoar antidote" or less commonaly ægagropile or egagropile (2-4). It was believed to have the power of a universal antidote that works against any poison, and a glass containing a bezoar could neutralize any poison poured into it. In science, it is a mass of hair or undigested vegetable matter found in a human or animal intestines, similar to a hairball. Otherwise, the name could derive from a kind of Turkish goat whose name is just bezoar. Usually, it is found trapped in every part of the gastrointestinal system and must be distinguished by pseudobezoar, which is an nondigestible object voluntarily introduced into the digestive tract. The most common causes are a previous gastric surgery such as a gastric band (for weight loss) or gastric bypass, a reduced stomach acid (hypochlorhydria) or decreased stomach size, and a delayed gastric emptying, typically due to diabetes, autoimmune disorders, or mixed connective tissue disease. Seed bezoars are usually found in the rectum of patients without predisposing factors, causing constipation and pain. Rectal impaction is common after ingestion of seeds, while a true occlusion is rare. Although several cases of phytobezoars composed of various types of seeds are reported in the literature, bezoars of pumpkin seeds have rarely been reported. The authors report a case of fecal impaction by pumpkin seed bezoars with abdominal pain: a difficulty to void with subsequent rectal inflammation and hemorrhoid enlargement was observed. The patient underwent a successful manual disimpaction.
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Affiliation(s)
- Maurizio Gentile
- Department of General Surgery, Endocrinology, Orthopedics and Rehabilitation, Federico II University of Naples, Naples, Italy
| | - Lorenzo Vergara
- Department of General Surgery, Endocrinology, Orthopedics and Rehabilitation, Federico II University of Naples, Naples, Italy
| | - Vincenzo Schiavone
- Department of General Surgery, Endocrinology, Orthopedics and Rehabilitation, Federico II University of Naples, Naples, Italy
| | | | - Luigi Sivero
- Department of Medicine and Surgery for Digestive Tract Diseases, Federico II University of Naples, Naples, Italy
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Haggui B, Hidouri S, Ksia A, Oumaya M, Mosbahi S, Messaoud M, Youssef SB, Sahnoun L, Mekki M, Belghith M, Nouri A. Management of trichobezoar: About 6 cases. Afr J Paediatr Surg 2022; 19:102-104. [PMID: 35017380 PMCID: PMC8809465 DOI: 10.4103/ajps.ajps_110_20] [Citation(s) in RCA: 14] [Impact Index Per Article: 4.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/08/2022] Open
Abstract
BACKGROUND Trichobezoar is an uncommon clinical entity in which ingested hair mass accumulates within the digestive tract. It is generally observed in children and young females with psychological disorders. It can either be found as an isolated mass in the stomach or may extend into the intestine. Untreated cases may lead to grave complications. MATERIAL AND METHODS We retrospectively analyzed the clinical data of six patients treated for trichobezoar in Monastir pediatric surgery department during 16-year-period between 2004 and 2019. Imaging (abdominal computed tomography and upper gastroduodenal opacification) and gastroduodenal endoscopy were tools of diagnosis. RESULTS Our study involved 6 girls aged 4 to 12. Symptoms were epigastric pain associated with vomiting of recently ingested food in 3 cases and weight loss in one case. Physical examination found a hard epigastric mass in all cases. The trichobezoar was confined to the stomach in 4 cases. An extension into the jejunum was observed in 2 cases. Surgery was indicated in all patients. In two cases, the attempt of endoscopic extraction failed and patients were then operated on. All patients had gastrotomy to extract the whole bezoar even those with jejunal extension. Psychiatric follow-up was indicated in all cases. The six girls have evolved well and did not present any recurrence. CONCLUSION open surgery still plays a crucial role in Trichobezoard management . After successful treatment, psychiatric consultation is imperative to prevent reccurrence and improve long term prognosis.
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Affiliation(s)
- Besma Haggui
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Saida Hidouri
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Amine Ksia
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Meriem Oumaya
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Sana Mosbahi
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Marwa Messaoud
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Sabrine Ben Youssef
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Lassaad Sahnoun
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Mongi Mekki
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Mohsen Belghith
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
| | - Abdellatif Nouri
- Department of Paediatric Surgery, Fattouma Bourguiba Hospital, Monastir Medical School, Monastir University Tunisia; Research Laboratory LR12SP13 Tunisian Ministry of Research, Tunisia
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Edwards M, Kaz A, Wander PL. Trichobezoar Without Trichotillomania-a Case Report. J Gen Intern Med 2022; 37:962-965. [PMID: 34981351 PMCID: PMC8904306 DOI: 10.1007/s11606-021-07194-6] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 04/13/2021] [Accepted: 10/01/2021] [Indexed: 11/27/2022]
Affiliation(s)
- Mitchell Edwards
- Veterans Affairs Puget Sound Health Care System, Hospital and Specialty Medicine, Seattle, WA, USA.
- Department of Medicine, University of Washington, Seattle, WA, USA.
| | - Andrew Kaz
- Veterans Affairs Puget Sound Health Care System, Hospital and Specialty Medicine, Seattle, WA, USA
- Department of Medicine, University of Washington, Seattle, WA, USA
| | - Pandora L Wander
- Veterans Affairs Puget Sound Health Care System, Hospital and Specialty Medicine, Seattle, WA, USA
- Department of Medicine, University of Washington, Seattle, WA, USA
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20
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Ota K, Kawaguchi S, Iwatsubo T, Nishida S, Tanaka H, Mori Y, Nakajima N, Hakoda A, Sugawara N, Kojima Y, Takeuchi T, Sakaguchi M, Higuchi K. Tannin-phytobezoars with Gastric Outlet Obstruction Treated by Dissolution with Administration and Endoscopic Injection of Coca-Cola ®, Endoscopic Crushing, and Removal (with Video). Intern Med 2022; 61:335-338. [PMID: 34334573 PMCID: PMC8866791 DOI: 10.2169/internalmedicine.8090-21] [Citation(s) in RCA: 6] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/18/2022] Open
Abstract
A 77-year-old man complained of postmeal vomiting and sustained general fatigue. An abdominal computed tomography scan showed massive gastric expansion and fluid storage. Gastroscopy revealed four gastric bezoars that were considered to have caused pyloric ring obstruction. The patient was asked to drink 500 mL per day of Coca-Cola® for 4 days. On the fourth day, we performed endoscopic crushing and removal by injecting Coca-Cola®, cutting the softened bezoar with endoscopic snares, and collecting the pieces with endoscopic nets. We herein report (with a video presentation) a rare case of tannin-phytobezoars endoscopically removed with the administration and injection of Coca-Cola®.
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Affiliation(s)
- Kazuhiro Ota
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Shimpei Kawaguchi
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Taro Iwatsubo
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Shinya Nishida
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Hironori Tanaka
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Yosuke Mori
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Noriyuki Nakajima
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Akitoshi Hakoda
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Noriaki Sugawara
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Yuichi Kojima
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | - Toshihisa Takeuchi
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
| | | | - Kazuhide Higuchi
- Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
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21
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DeMarco GB, Jiang Q, Fischer EA. POCUS Finding of Portal Venous Gas: An Unusual Consequence of an Amyloid Dysmotility Related Bezoar. POCUS JOURNAL 2022; 7:201-204. [PMID: 36896385 PMCID: PMC9983721 DOI: 10.24908/pocus.v7i2.15681] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 11/23/2022]
Abstract
A 73-year-old male with a recent finding of pericardial effusion and syncope was evaluated with point of care ultrasound for recurrent effusion. A thickened left ventricle and recurrent pericardial effusion were found. Unexpectedly, on scanning the inferior vena cava (IVC), extensive portal venous gas was identified, a finding previously described as a "meteor shower". Subsequent imaging by computed tomography (CT) identified gastric edema and peri-gastric vessel gas as the source of the portal gas, attributed to a large bezoar. The bezoar was later classified as a phytobezoar and the patient was found to have both cardiac and gastrointestinal manifestations of light chain amyloidosis. The gastrointestinal amyloidosis predisposed the patient to bezoar formation owing to associated dysmotility, a rare complication of an unusual manifestation of systemic amyloid.
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Affiliation(s)
- Grace B DeMarco
- Department of Medicine, MedStar Georgetown University Hospital Washington, DC
| | - Qiuchen Jiang
- Department of Medicine, MedStar Georgetown University Hospital Washington, DC
| | - Ernest A Fischer
- Department of Medicine, MedStar Georgetown University Hospital Washington, DC
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22
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Hu T, Zhang J, Liu Y, Chen L, Cen W, Wu W, Huang Q, Sun X, Stock S, Zippi M, Zimmer V, Basharat Z, Hong W. Evaluation of the risk factors for severe complications and surgery of intestinal foreign bodies in adults: a single-center experience with 180 cases. Gastroenterol Rep (Oxf) 2022; 10:goac036. [PMID: 35966628 PMCID: PMC9366183 DOI: 10.1093/gastro/goac036] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/14/2021] [Revised: 04/17/2022] [Accepted: 05/20/2022] [Indexed: 02/07/2023] Open
Abstract
BACKGROUND Foreign bodies (FBs) lodged in the intestine or causing intestinal complications are uncommon in clinical practice but may pose diagnostic difficulties and prove life-threatening. This study aimed to evaluate the risk factors for severe complications and surgery to aid clinicians in the diagnosis and management of intestinal FBs. METHODS We performed a retrospective analysis of patients in whom FBs were lodged in the intestine or caused complications from 2010 to 2020 in the First Affiliated Hospital of Wenzhou Medical University (Zhejiang, China). The characteristics of the patients and FBs, symptoms, imaging findings, diagnostics, treatment strategies, and clinical outcomes were analysed. Furthermore, the risk factors for complications and surgery were investigated. RESULTS In total, 180 patients were included in our study. Most patients (76.1%) were unable to provide a history of ingestion. Bezoars were the most common FBs (35.6%). The FBs were mainly located in the duodenum (32.8%) and the ileum (27.8%). Surgical removal of FBs was successful in 89 (49.4%) patients and endoscopic removal in 54 (30.0%) patients. Eleven with perforations were treated conservatively. FBs located in the jejunum or ileum were more likely to cause severe complications than those located in the duodenum. FBs located in the jejunum, ileum, or sigmoid colon were more likely to undergo surgery, and severe complications were an independent risk factor for surgery. CONCLUSION Intestinal FBs, often localized in angulation, are likely to be misdiagnosed because most patients do not provide a history of FB ingestion. Surgery and endoscopic therapy are the most commonly used treatment modalities. Surgery is not mandatory in clinically stable patients with small and contained perforations. FBs located in the jejunum or ileum are risk factors for both complications and surgery.
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Affiliation(s)
| | | | | | - Lifang Chen
- Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P. R. China
| | - Wei Cen
- The First Clinical College, Wenzhou Medical University, Wenzhou, Zhejiang, P. R. China
| | - Wenzhi Wu
- Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P. R. China
| | - Qingke Huang
- Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P. R. China
| | - Xuecheng Sun
- Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P. R. China
| | - Simon Stock
- Department of Surgery, World Mate Emergency Hospital, Battambang, Cambodia
| | - Maddalena Zippi
- Unit of Gastroenterology and Digestive Endoscopy, Sandro Pertini Hospital, Rome, Italy
| | - Vincent Zimmer
- Department of Medicine II, Saarland University Medical Center, Saarland University, Homburg, Germany
| | - Zarrin Basharat
- Jamil-ur-Rahman Center for Genome Research, Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
| | - Wandong Hong
- Corresponding author. Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325025, Zhejiang, P. R. China. Tel: +86-577-88069817; Fax: +86-577-88069555; ;
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Chin X, Ng JY. Acute Presentation of Rapunzel Syndrome and a Review of Bezoars. Cureus 2021; 13:e20785. [PMID: 35111469 PMCID: PMC8794762 DOI: 10.7759/cureus.20785] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 12/27/2021] [Indexed: 11/25/2022] Open
Abstract
Bezoars have different compositions and can be subdivided into trichobezoar, phytobezoar, pharmacobezoar, lactobezoar and food bolus. The reported incidence of bezoar is 0.4% with phytobezoar being the commonest. Rapunzel syndrome is an extremely rare complication when trichobezoar crosses the pylorus to enter the duodenum, ileum and colon. We present the case of a 29-year-old female with a one-week history of abdominal pain, anorexia, nausea, vomiting, constipation, lethargy and a one-year history of increasing abdominal mass. Physical examination revealed a 20 cm palpable mass extending from the left upper quadrant to the umbilicus. Laboratory investigations demonstrated iron deficiency anemia and CT showed two well-defined foci within the gastric lumen consistent with trichobezoars. She was managed conservatively during her hospital stay and discharged home with a plan for elective laparotomy. We present this case to discuss the management of trichobezoars and to highlight the importance of early recognition of recurrence to avoid severe complications.
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Alemam A, Shin D, Balar B. Gastric Bezoar: Cause of Weight Loss in a Patient With Previous Bariatric Surgery. Cureus 2021; 13:e20139. [PMID: 35003973 PMCID: PMC8723780 DOI: 10.7759/cureus.20139] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 11/29/2021] [Indexed: 11/17/2022] Open
Abstract
Gastric bezoar is a concretion of undigested material found in the stomach and is classified by its composition. Patients may remain asymptomatic or present with a variety of gastrointestinal symptoms. Upper gastrointestinal endoscopy is required to establish the diagnosis. Treatment options include chemical dissolution, endoscopic removal, or surgical removal. Here, we present a rare case of gastric bezoar in a patient with a remote history of bariatric surgery presenting with acute weight loss.
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Maehata T, Kiyokawa H, Nakahara K, Kobayashi S, Itoh F. Successfully combined therapy of Coca-Cola and endoscopic treatment for a giant diospyrobezoar in the duodenum using the electrosurgical endo-knife and ileus tube. VideoGIE 2021; 6:475-477. [PMID: 34667915 PMCID: PMC8504150 DOI: 10.1016/j.vgie.2021.06.008] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/01/2022] Open
Affiliation(s)
- Tadateru Maehata
- Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
| | - Hirofumi Kiyokawa
- Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
| | - Kazunari Nakahara
- Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
| | - Shinjiro Kobayashi
- Department of Gastroenterological and General Surgery, St. Marianna University School of Medicine, Kawasaki, Japan
| | - Fumio Itoh
- Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
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Seth AK, Gupta MK, Bansal RK, Verma RK, Kaur G. Colonoscopic Instillation of Coca-Cola for Evacuation of Large Fecaloma: A Report of Two Cases and Review of Literature. JOURNAL OF HEALTH AND ALLIED SCIENCES NU 2021. [DOI: 10.1055/s-0041-1734340] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/20/2022]
Abstract
Abstract
Introduction Fecaloma is a large mass of organized hardened feces causing impaction, usually in rectum and sigmoid colon. Medical management usually entails digital evacuation, use of clearance enema, and oral laxatives. We report two patients managed successfully with colonoscopic instillation of Coca-Cola and review the literature.
Case Report Patient 1: A 37-year-old male presented with firm, nontender, pitting mass over lower abdomen for 2 months and inability to pass stool for 1 month. Per-rectal examination and imaging confirmed presence of solid stool with gross distension of rectum and sigmoid colon. Attempts at clearance of stool with conventional methods were unsuccessful. At colonoscopy, 4 L of Coca-Cola was instilled into descending and sigmoid colon, leading to evacuation of 10 L of fragmented and liquid stool.Patient 2: A 72-year-old diabetic lady presented with constipation and tender, firm pelvic mass extending till mid-abdomen for 6 months. Per-rectal examination revealed presence of hard stool. Imaging confirmed large amount of fecal matter in dilated rectum, sigmoid, and descending colon. Attempts at evacuating stool with digital evacuation, sodium phosphate enema, and oral polyethylene glycol were unsuccessful. At colonoscopy, two sittings of instillation of 990 mL of Coca-Cola Light each were done into sigmoid colon over 2 days, resulting in clearance.
Conclusion Colonoscopic instillation of Coca-Cola may be effective in evacuation of large fecaloma from rectum, sigmoid, and descending colon when refractory to use of conventional methods like digital disimpaction, rectal enema, and oral laxatives.
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Affiliation(s)
- Avnish Kumar Seth
- Department of Gastroenterology & Hepatobiliary Sciences, Fortis Memorial Research Institute, Gurugram, Haryana, India
| | - Mahesh Kumar Gupta
- Department of Gastroenterology & Hepatobiliary Sciences, Fortis Memorial Research Institute, Gurugram, Haryana, India
| | - Rinkesh Kumar Bansal
- Department of Gastroenterology & Hepatobiliary Sciences, Fortis Memorial Research Institute, Gurugram, Haryana, India
| | - Radha Krishan Verma
- Department of Radiology, Fortis Memorial Research Institute, Gurugram, Haryana, India
| | - Gursimran Kaur
- Department of Gastroenterology & Hepatobiliary Sciences, Fortis Memorial Research Institute, Gurugram, Haryana, India
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Choi HH, Kim Y. Use of Olive Oil for the Treatment of a Phytobezoar: A Case Report. THE EWHA MEDICAL JOURNAL 2021; 44:89-92. [DOI: 10.12771/emj.2021.44.3.89] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Subscribe] [Scholar Register] [Received: 05/24/2021] [Revised: 06/27/2021] [Accepted: 07/16/2021] [Indexed: 08/30/2023]
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28
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Wang TT, He JJ, Liu J, Chen WW, Chen CW. Acute pancreatitis and small bowel obstruction caused by a migratory gastric bezoar after dissolution therapy: A case report. World J Clin Cases 2021; 9:3114-3119. [PMID: 33969098 PMCID: PMC8080734 DOI: 10.12998/wjcc.v9.i13.3114] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/15/2020] [Revised: 02/08/2021] [Accepted: 03/03/2021] [Indexed: 02/06/2023] Open
Abstract
BACKGROUND Bezoars are conglomerates of indigestible foreign material that can be found in the gastrointestinal tract. Gastric ulcer, gastrointestinal perforation, and intestinal obstruction are the main complications. Acute pancreatitis secondary to bezoar is rare. Here, we present a rare case of a migratory gastric bezoar complicated by acute pancreatitis and small bowel obstruction after dissolution therapy.
CASE SUMMARY A-65-year-old woman underwent gastroscopy because of epigastric pain, which revealed a huge bezoar and a gastric ulcer 10 d prior. The patient was discharged with a prescription of drinking 1 L Coca-Cola daily for 6 d, without repeat gastroscopy. However, she suddenly developed epigastric pain, nausea and vomiting for 3 d. Abdominal computed tomography (CT) revealed mild inflammation of the pancreas. Magnetic resonance cholangiopancreatography showed no abnormalities in the pancreatic duct or common bile duct. The nasogastric tube still showed drainage of more than 1.6 L of dark fluid each day after symptomatic treatment. Abdominal CT re-examination suggested intestinal obstruction. Esophagogastroduodenoscopy revealed a huge yellowish hard mass in the jejunal lumen, and we used the basket and net to fragment the bezoar. She was discharged with a good outcome.
CONCLUSION Endoscopic therapy is the first choice for gastric bezoars. When mechanical disintegration cannot be achieved, timing of repeat endoscopy is important during Coca-Cola dissolution therapy.
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Affiliation(s)
- Ting-Ting Wang
- Department of Gastroenterology, The First Clinical Medical College, Dalian Medical University, Dalian 116044, Liaoning Province, China
| | - Jia-Jun He
- Department of Gastroenterology, The First Clinical Medical College, Dalian Medical University, Dalian 116044, Liaoning Province, China
| | - Jun Liu
- Endoscopy Center, Department of Gastroenterology, Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China
| | - Wei-Wei Chen
- Endoscopy Center, Department of Gastroenterology, Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China
| | - Chao-Wu Chen
- Endoscopy Center, Department of Gastroenterology, Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China
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Chineka R, Mukosera T, Dzvanga N, Gwanda B. Case report-An unusual diagnosis of a gastric phytobezoar in a middle-aged woman. Clin Case Rep 2021; 9:e04077. [PMID: 34026134 PMCID: PMC8133075 DOI: 10.1002/ccr3.4077] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/26/2021] [Revised: 02/28/2021] [Accepted: 03/07/2021] [Indexed: 11/12/2022] Open
Abstract
A gastric phytobezoar is an uncommon finding. The most frequent symptoms are dyspepsia, abdominal pain, nausea, and vomiting (Gastroenterology Report, 7, 2019, 74). It is an important differential to remember in patients with risk factors for developing phytobezoars because phytobezoars can be managed conservatively in most cases.
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Abstract
OBJECTIVES To determine the demographics, potential risk factors, endoscopic interventions and outcomes relating to gastric bezoars in pediatric patients; and comparing results with previously published literature. METHODS Retrospective series by chart review of patients identified by International Classification of Diseases-9 codes 938 and 935, using the following Medical Subject Headings: 1, term bezoar; 2, Keywords gastric bezoar∗ or gastric foreign body∗. RESULTS Thirty pediatric patients between ages of 2 to 18 years were found with gastric bezoars, with a female predominance. Majority had a phytobezoar. Six patients were diagnosed with dysautonomia, implying possible role of autonomic dysfunction contributing to abnormal gastric retention. Frequent symptoms included abdominal pain, nausea and vomiting, a decrease in appetite, and unintentional weight loss. A higher prevalence of underlying gastrointestinal disorders was found in those with bezoars. Nuclear medicine gastric emptying scan performed in 13 children was significantly abnormal in only 4 of these children. Most patients were treated with endoscopic removal of the bezoar. Endoscopic removal was accomplished by Roth net, generally requiring multiple passes. At follow-up, most of the children had improvement of symptoms, with bezoar recurrence in 1 patient. CONCLUSIONS This is to our knowledge the largest series of gastric bezoars in pediatrics. On the basis of our review, phytobezoars may be under-reported in pediatrics. Bezoars should be considered in children presenting with chronic abdominal pain, nausea, and vomiting; even in developmentally normal children and those with normal gastric emptying. We suggest that dysautonomia and underlying gastrointestinal disorders may be potential risk factors.
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Marginean CO, Melit LE, Sasaran MO, Marginean R, Derzsi Z. Rapunzel Syndrome-An Extremely Rare Cause of Digestive Symptoms in Children: A Case Report and a Review of the Literature. Front Pediatr 2021; 9:684379. [PMID: 34178901 PMCID: PMC8219913 DOI: 10.3389/fped.2021.684379] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/23/2021] [Accepted: 05/05/2021] [Indexed: 11/13/2022] Open
Abstract
Rapunzel syndrome is an extremely rare condition seen in adolescents or young females with psychiatric disorders consisting of a gastric trichobezoar with an extension within the small bowel. The delays in diagnosis are common since in its early stages, it is usually asymptomatic. We report the case of a 13-year-old girl admitted in our clinic for abdominal pain, anorexia, and weight loss. The clinical exam pointed out diffuse alopecia, a palpable mass in the epigastric area, and abdominal tenderness at palpation, the patient weighing 32 kg. The laboratory tests showed anemia. The abdominal ultrasound showed a gastric intraluminal mass with a superior hyperechoic arc. The upper digestive endoscopy revealed a mass formed by hair, mucus, and food occupying the gastric cavity with the extension into the duodenum confirming the diagnosis of Rapunzel syndrome. The giant trichobezoar of 511 g, measuring 17 × 7 × 6.5 cm with a tail of approximately 3 cm, was successfully removed through laparotomy. Although rare, Rapunzel syndrome must never be forgotten as a differential diagnosis for digestive symptoms since its early detection hinders the occurrence of further complications.
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Affiliation(s)
- Cristina Oana Marginean
- Department of Pediatrics I, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, Târgu Mureş, Romania
| | - Lorena Elena Melit
- Department of Pediatrics I, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, Târgu Mureş, Romania
| | - Maria Oana Sasaran
- Department of Pediatrics III, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, Târgu Mureş, Romania
| | - Razvan Marginean
- Department of Pediatric Surgery, County Emergency Clinical Hospital of Târgu Mureş, Târgu Mureş, Romania
| | - Zoltan Derzsi
- Department of Pediatric Surgery, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, Romania
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Intestinal bezoar aggravated by hypomotility of ischemic small intestine: A case report. ADVANCES IN DIGESTIVE MEDICINE 2020. [DOI: 10.1002/aid2.13248] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/07/2022]
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Liu LN, Wang L, Jia SJ, Wang P. Clinical Features, Risk Factors, and Endoscopic Treatment of Bezoars: A Retrospective Analysis from a Single Center in Northern China. Med Sci Monit 2020; 26:e926539. [PMID: 33027245 PMCID: PMC7549533 DOI: 10.12659/msm.926539] [Citation(s) in RCA: 8] [Impact Index Per Article: 1.6] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/20/2022] Open
Abstract
Background The aims of this study were to summarize the clinical characteristics and risk factors for bezoars and to analyze the effectiveness and safety of the endoscopic treatment of bezoars. Material/Methods From January 2015 to February 2020, 75 of the 23 950 patients who underwent gastroscopic examination in our medical center were diagnosed with bezoars. Clinical and treatment information for these patients was collected retrospectively and analyzed. Results The detection rate of bezoars was 0.31%. Risk factors included the time of year (autumn and winter seasons), alcohol consumption, hypertension, diabetes, and residing in the Mentougou district, which is rich in hawthorn and persimmon. Abdominal pain (90.7%) and bloating (80.0%) were common clinical symptoms of bezoars, while gastric mucosa erosion (90.7%) and gastric ulcers (60%) were common manifestations on endoscopic examination. Six patients with bezoars were successfully discharged after drug treatment. The success rate for bezoars treated by gastroscopic lithotripsy was 94.2% (65/69 patients). The factors affecting the therapeutic effect of bezoars include patient age (P=0.025) and bezoar size (P=0.042). Patients with bezoars larger than 9 cm were significantly more likely to have intestinal obstructions than were patients with bezoars smaller than 9 cm (P<0.001). Conclusions Bezoars mainly occur in elderly patients with diseases such as gastrointestinal dyspraxia and diabetes, and are most common in hawthorn and persimmon producing areas. Endoscopic treatment is safe and effective for bezoars in general, but intestinal obstruction should be considered for bezoars larger than 9 cm.
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Affiliation(s)
- Lin-Na Liu
- Department of Gastroenterology, Peking University Shougang Hospital, Beijing, China (mainland)
| | - Lei Wang
- Department of Urology, Peking University Shougang Hospital, Beijing, China (mainland).,Peking University Wujieping Urology Center, Peking University Health Science Center, Beijing, China (mainland)
| | - Shu-Juan Jia
- Department of Gastroenterology, Peking University Shougang Hospital, Beijing, China (mainland)
| | - Peng Wang
- Department of Gastroenterology, Peking University Shougang Hospital, Beijing, China (mainland)
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Banse HE. Management of phytobezoars. EQUINE VET EDUC 2020. [DOI: 10.1111/eve.13114] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/28/2022]
Affiliation(s)
- H. E. Banse
- Department of Veterinary Clinical Sciences School of Veterinary Medicine Louisiana State University Baton Rouge Louisiana USA
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Livesey LC, Yorke E, Parra A, Gray Q, Davies C, Weldon D, Schumacher J, Kimura S, Howard C, Sierra‐Rodriguez T, Mora‐Pereira M. Use of a carbonated beverage to disintegrate a phytobezoar obstructing the intrathoracic portion of the oesophagus of a horse. EQUINE VET EDUC 2020. [DOI: 10.1111/eve.13082] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/27/2022]
Affiliation(s)
- L. C. Livesey
- Tuskegee University College of Veterinary Medicine Auburn AlabamaUSA
| | - E. Yorke
- Tuskegee University College of Veterinary Medicine Auburn AlabamaUSA
| | - A. Parra
- Tuskegee University College of Veterinary Medicine Auburn AlabamaUSA
| | - Q. Gray
- Tuskegee University College of Veterinary Medicine Auburn AlabamaUSA
| | - C. Davies
- Tuskegee University College of Veterinary Medicine Auburn AlabamaUSA
| | - D. Weldon
- Southeast Equine Veterinary Services Phenix City AlabamaUSA
| | - J. Schumacher
- J.T. Vaughan Large Animal Teaching Hospital Auburn University College of Veterinary Medicine Auburn Alabama USA
| | - S. Kimura
- J.T. Vaughan Large Animal Teaching Hospital Auburn University College of Veterinary Medicine Auburn Alabama USA
| | - C. Howard
- Bluegrass Animal Clinic Grayson Kentucky USA
| | - T. Sierra‐Rodriguez
- J.T. Vaughan Large Animal Teaching Hospital Auburn University College of Veterinary Medicine Auburn Alabama USA
| | - M. Mora‐Pereira
- J.T. Vaughan Large Animal Teaching Hospital Auburn University College of Veterinary Medicine Auburn Alabama USA
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Hancher J, Fisher J, Shenvi C. Severe hypernatremia and gastric dilation from chronic eating disorder and intentional salt ingestion. Am J Emerg Med 2020; 38:1700.e1-1700.e3. [DOI: 10.1016/j.ajem.2020.04.082] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/03/2020] [Revised: 04/21/2020] [Accepted: 04/23/2020] [Indexed: 11/15/2022] Open
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Lithobezoar: A Case Report and Literature Review of an Infrequent Cause of Abdominal Pain. MEDICAL BULLETIN OF SISLI ETFAL HOSPITAL 2020; 53:445-449. [PMID: 32377125 PMCID: PMC7192304 DOI: 10.14744/semb.2018.52714] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 12/12/2017] [Accepted: 03/19/2018] [Indexed: 11/20/2022]
Abstract
A bezoar is the accumulation of indigestible substances in the gastrointestinal system. Presently described is the case of a 47-year-old male patient who was admitted to the clinic with nausea, vomiting, pain, and abdominal distension. He had a medical history of obsessive-compulsive disorder. He had begun eating soil in the previous 3 to 4 months. Gastroscopy revealed a large, solid, clay-like mass in the stomach. Surgery was successfully performed to remove the collected soil, but unfortunately, the patient died due to an acute myocardial infarction on the postoperative fourth day. Physicians should keep bezoars in mind in cases of unexplained abdominal symptoms, especially in females and patients with psychiatric disorders. Psychiatric disorders are often ignored by surgeons during examinations, which can lead to serious and life-threatening complications.
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Lin L, Wang C, Wu J, Liu K, Liu H, Wei N, Lin W, Jiang G, Tai W, Su H. Gastric phytobezoars: the therapeutic experience of 63 patients in Northern China. REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS 2019; 112:12-15. [PMID: 31599640 DOI: 10.17235/reed.2019.6400/2019] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 12/20/2022]
Abstract
INTRODUCTION Sixty-three patients with gastric phytobezoars were reviewed. METHODS forty-eight (76.2%) patients received endoscopic combined with chemical therapies and 15 (23.8%) received only chemical therapy initially. Fifty-one (81.0%) patients achieved complete removal (only chemical therapy 14/15), while 12 (19.0%) received further endoscopic therapies. RESULTS finally, 62 (98.4%) patients achieved a complete removal. Considering only patients with combined treatment as a first approach, treatment success was associated with a softer phytobezoar consistency (p = 0.023). CONCLUSION in conclusion, most patients achieve a favorable outcome. Chemical therapy is useful in selected cases. Repeated endoscopic therapies may be needed in order to completely remove phytobezoars with a hard consistency.
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Affiliation(s)
- Lin Lin
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University, China
| | - Canghai Wang
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Jing Wu
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Kuiliang Liu
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Hong Liu
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Nan Wei
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Wu Lin
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
| | - Guojun Jiang
- Beijing Shijitan Hospital, Capital Medical University
| | - Weiping Tai
- Gasstroenterology, Beijing Shijitan Hospital, Capital Medical University
| | - Hui Su
- Gastroenterology, Beijing Shijitan Hospital. Capital Medical University
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Romero RJ, Martínez L, Villegas IRV. Fitobezoar posterior a mini bypass gástrico por laparoscopia. REVISTA COLOMBIANA DE CIRUGÍA 2019. [DOI: 10.30944/20117582.441] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/04/2022] Open
Abstract
Introducción. La miniderivación (mini-bypass) gástrica por laparoscopia es un procedimiento bariátrico que recientemente ha cobrado popularidad. Las alteraciones del tubo digestivo generadas por estos procedimientos pueden ocasionar diversas complicaciones, algunas raras, como los bezoares.
Caso clínico. Se presenta el caso de una mujer de 52 años de edad con antecedentes de diabetes mellitus y obesidad, que fue tratada con una miniderivación gástrica por laparoscopia. Nueve meses después del procedimiento, presentó dolor en el epigastrio, intolerancia a los alimentos y vómito, por lo cual se dio tratamiento sintomático sin obtener mejoría. Se practicó una endoscopia de vías digestivas altas, cuyo hallazgo fue un bezoar de coco que obstruía parcialmente la anastomosis. El bezoar se trituró y se extrajo por endoscopia.
Discusión. Los pacientes con antecedentes de cirugía bariátrica tienen mayor riesgo de presentar bezoares por la modificación del tubo digestivo. Estos pacientes presentan frecuentemente síntomas de dispepsia, por lo que la sintomatología inespecífica puede confundirse o subestimarse. Se debe considerar practicar una endoscopia en todos aquellos con antecedentes de cirugía bariátrica que presenten vómito persistente después de ingerir alimentos o síntomas de obstrucción gástrica.
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Garcia DI, Taylor Head W, Lesher AP. Parsnip phytobezoar causing small bowel obstruction. JOURNAL OF PEDIATRIC SURGERY CASE REPORTS 2019. [DOI: 10.1016/j.epsc.2019.101227] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/26/2022] Open
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Upper Gastrointestinal Manifestation of Bezoars and the Etiological Factors: A Literature Review. Gastroenterol Res Pract 2019; 2019:5698532. [PMID: 31396274 PMCID: PMC6664490 DOI: 10.1155/2019/5698532] [Citation(s) in RCA: 19] [Impact Index Per Article: 3.2] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/01/2019] [Revised: 04/28/2019] [Accepted: 05/09/2019] [Indexed: 12/19/2022] Open
Abstract
A gastric bezoar is a compact mass of indigestible foreign materials that accumulate and consolidate in the stomach; however, it can be found in other sites of the gastrointestinal tract. The causative manner of this condition is complex and multifactorial. The main purpose of the review was to raise awareness among clinicians, particularly gastroenterologists, that patients with certain risk factors or comorbid conditions are predisposed to gastric bezoar formation. Early diagnosis and prompt intervention are crucial to avoid bezoar-induced complications. Upper gastrointestinal endoscopy is the standard diagnostic and therapeutic method for gastric bezoars. However, for large size bezoars, surgical intervention is needed.
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Hatoyama K, Taniyama Y, Sakurai T, Hikage M, Sato C, Okamoto H, Takaya K, Onodera Y, Kamei T. Reconstructed gastric conduit obstruction caused by a bezoar after esophagectomy: a case report. BMC Surg 2019; 19:59. [PMID: 31174520 PMCID: PMC6556038 DOI: 10.1186/s12893-019-0525-5] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/24/2018] [Accepted: 05/30/2019] [Indexed: 11/22/2022] Open
Abstract
Background Bezoars are rare but may cause gastrointestinal obstruction and ulcers. To the best of our knowledge, only two cases of bezoars in the reconstructed gastric conduit have been reported, but there has been no report on reconstructed gastric conduit obstruction due to bezoars. Case presentation A 60-year-old man presented to our clinic with abdominal pain and vomiting that occurred suddenly after dinner. Three years before presentation, he had undergone radical thoracoscopic esophagectomy followed by reconstruction of the gastric conduit through the posterior sternum, for esophageal cancer. Enhanced computed tomography scans showed distension of only the gastric conduit without ischemia and distension of the small intestine. According to our findings, we initially diagnosed the patient with postoperative intestinal obstruction caused by adhesions. After conservative treatment failed, the patient underwent an endoscopic study that showed a bezoar at the pylorus ring. We initially failed to remove the bezoar endoscopically because of its large size; hence, we attempted enzymatic dissolution. Three days after the first endoscopic study, the bezoar was disintegrated using a snare and extracted during a second endoscopy. The patient recovered uneventfully and presented with no complications during the 1-year follow-up interval. Conclusion In cases wherein the discharge of materials in the reconstructed gastric conduit is delayed, bezoars should be considered in the differential diagnosis, and an endoscopic study should be performed to verify the cause of obstruction.
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Affiliation(s)
- Keiichiro Hatoyama
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.
| | - Yusuke Taniyama
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan
| | - Tadashi Sakurai
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan
| | - Makoto Hikage
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan
| | - Chiaki Sato
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan
| | - Hiroshi Okamoto
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan
| | - Kai Takaya
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan
| | - Yu Onodera
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan
| | - Takashi Kamei
- Department of Surgery, Tohoku University Graduate School of Medicine/Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan
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Manatakis DK, Acheimastos V, Antonopoulou MI, Balalis D, Korkolis DP. Gastrointestinal Seed Bezoars: A Systematic Review of Case Reports and Case Series. Cureus 2019; 11:e4686. [PMID: 31333915 PMCID: PMC6636697 DOI: 10.7759/cureus.4686] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/05/2022] Open
Abstract
Seed bezoars are a distinct subcategory of phytobezoars, caused by indigestible vegetable or fruit seeds. The aim of our study was to present a comprehensive review on seed bezoars, focusing on epidemiology, symptomatology, diagnosis and treatment options. A systematic review of the English literature (1980-2018) was conducted, using PubMed, Embase and Google Scholar databases. Fifty-two studies fulfilled the inclusion criteria, with a total of 153 patients, the majority of whom (72%) came from countries around the Eastern Mediterranean and the Middle East. Patients complained primarily about constipation (63%), abdominal/rectal pain (19%) or intestinal obstruction (17%). Most seed bezoars were found in the rectum (78%) and the terminal ileum (16%). Risk factors were recognised in 12% of cases. Manual disimpaction under general anaesthesia was the procedure of choice in 69%, while surgery was required in 22% of cases. Seed bezoars appear to represent a different pathophysiological process compared to fibre bezoars. Seeds usually pass through the pylorus and ileocaecal valve, due to their small size, and accumulate gradually in the colon. Seed bezoars are usually found in the rectum of patients without predisposing factors, causing constipation and pain. History and digital rectal examination are the mainstay of diagnosis, with manual extraction under general anaesthesia being the procedure of choice.
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Manatakis D, Sioula M, Passas I, Zerbinis H, Dervenis C. Rectal seed bezoar due to sunflower seed: a case report and review of the literature. Pan Afr Med J 2019; 31:157. [PMID: 31065317 PMCID: PMC6488252 DOI: 10.11604/pamj.2018.31.157.12539] [Citation(s) in RCA: 7] [Impact Index Per Article: 1.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/17/2017] [Accepted: 06/22/2018] [Indexed: 12/21/2022] Open
Abstract
Seed bezoars are a subcategory of phytobezoars, caused by consumption of indigestible vegetable or fruit seeds. We present the case of a 64-year-old male patient, who presented at the Emergency Department, complaining of constipation, tenesmus and rectal pain. History and digital examination revealed a rectal seed bezoar due to sunflower seeds, impacted in the lower rectum. The patient underwent manual disimpaction under general anaesthesia, after conservative measures failed. Seed bezoars represent a different pathophysiological process compared to fibre bezoars. They are usually found in the rectum of patients without predisposing factors, causing constipation and anorectal pain. History taking and digital rectal examination are the cornerstones of diagnosis, with manual disimpaction under general anaesthesia being the procedure of choice.
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Affiliation(s)
- Dimitrios Manatakis
- Department of Surgery, Konstantopouleio General Hospital "Agia Olga", Nea Ionia, Athens, Greece
| | - Maria Sioula
- Department of Surgery, Konstantopouleio General Hospital "Agia Olga", Nea Ionia, Athens, Greece
| | - Ioannis Passas
- Department of Surgery, Konstantopouleio General Hospital "Agia Olga", Nea Ionia, Athens, Greece
| | - Helen Zerbinis
- Department of Surgery, Konstantopouleio General Hospital "Agia Olga", Nea Ionia, Athens, Greece
| | - Christos Dervenis
- Department of Surgery, Konstantopouleio General Hospital "Agia Olga", Nea Ionia, Athens, Greece
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Mukai Y, Nishikawa N, Takahashi Y, Murata M. [Complications and troubleshooting at the initial introduction of Levodopa-carbidopa continuous infusion gel therapy: A single-center study]. Rinsho Shinkeigaku 2019; 59:177-184. [PMID: 30930364 DOI: 10.5692/clinicalneurol.cn-001243] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/05/2022]
Abstract
Levodopa-carbidopa intestinal gel (LCIG) therapy has been established as a device-aided treatment for advanced Parkinson's disease. We retrospectively investigated the issues related to LCIG therapy in patients with Parkinson's disease at our hospital from March 2014 to July 2018. The subjects were 18 patients including nine men and nine women. The mean duration of PD symptoms and motor fluctuation was 14.5 ± 5.9 and 7.2 ± 4.5 years, respectively. The mean age at initiation of LCIG was 60.1 ± 9.4 years and the mean treatment period was 21.1 ± 19.5 months. One hundred and sixteen LCIG-associated issues were observed, including pain at the gastrostomy site (23 cases), hypergranulation tissue (14 cases), skin redness and/or erosions (11 cases), cutaneous infections at the gastrostomy site (eight cases), percutaneous endoscopic gastrojejunostomy (PEG-J) tube occlusion in the gastrointestinal tract (19 cases), irremovable PEG-J tube (13 cases), dislocation of the PEG-J tube (six cases), and breakage of the connector (eight cases). The majority of these issues were easily diagnosed and could be managed by neurologists who are familiar with LCIG therapy.
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Affiliation(s)
- Yohei Mukai
- Department of Neurology, National Center Hospital, Parkinson's Disease & Movement Disorders Center, National Center of Neurology and Psychiatry, Japan
| | - Noriko Nishikawa
- Department of Neurology, National Center Hospital, Parkinson's Disease & Movement Disorders Center, National Center of Neurology and Psychiatry, Japan
| | - Yuji Takahashi
- Department of Neurology, National Center Hospital, Parkinson's Disease & Movement Disorders Center, National Center of Neurology and Psychiatry, Japan
| | - Miho Murata
- Department of Neurology, National Center Hospital, Parkinson's Disease & Movement Disorders Center, National Center of Neurology and Psychiatry, Japan
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Moghaddam ET, Tafazoli A. Cola Beverages: Clinical Uses versus Adverse Effects. CURRENT NUTRITION & FOOD SCIENCE 2019. [DOI: 10.2174/1573401313666170821130225] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/22/2022]
Abstract
Background: Excessive consumption of cola beverages is accompanied by numerous public health risks. But besides these well-known adverse effects, recently, several medical articles have been published that show some indications for cola beverages in clinical practice like resolution of gastrointestinal or feeding tube obstructions, increasing bioavailability and palatability of other medications, rehydration and other uses in healthcare settings. These approaches are not without shortcomings and complications.Methods:In this systematic review we tried to explore these new uses for practitioners and also reemphasize on the most evidence-based complications of cola consumption like bone loss and metabolic and cardiovascular adverse effects in cases of misuse and overuse from both clinical and nutritional points of view via searching the PubMed database.Results:We chose 145 journal articles from the most relevant ones plus 30 extra references and categorized their topics in two classes of medical uses and adverse effects.Conclusion:It could be stated that cola beverages have demonstrated interesting uses and benefits in medicine but their use should be regulated as strict as possible.
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Affiliation(s)
- Ehsan T. Moghaddam
- Orthodontics Department, School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran
| | - Ali Tafazoli
- School of Pharmacy, International Campus, Iran University of Medical Sciences, Tehran, Iran
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Paschos KA, Chatzigeorgiadis A. Pathophysiological and clinical aspects of the diagnosis and treatment of bezoars. Ann Gastroenterol 2019; 32:224-232. [PMID: 31040619 PMCID: PMC6479654 DOI: 10.20524/aog.2019.0370] [Citation(s) in RCA: 35] [Impact Index Per Article: 5.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/11/2018] [Accepted: 02/11/2019] [Indexed: 12/18/2022] Open
Abstract
Bezoars are intraluminal conglomerates of indigestible foreign materials that accumulate in the gastrointestinal (GI) tract. They consist of vegetable or fruit fibers, hairs or other substances; accordingly, bezoars are classified as phytobezoars, trichobezoars, pharmacobezoars, etc. Although sometimes asymptomatic, bezoars may cause serious symptoms, such as abdominal discomfort or pain, dysphagia, hematemesis, or even life-threatening entities (GI bleeding, obstruction or perforation). Current technological applications have contributed to the diagnostic and therapeutic approach to these masses, mainly through endoscopic techniques able to diagnose, fragment and extract bezoars, as well as laparoscopic and other surgical modalities that may be used to treat serious complications. Although bezoars were described centuries ago and the term was officially introduced in the mid nineties by Quain, they are still a demanding pathological entity. Their pathophysiology, accurate and prompt diagnosis, as well as successful and minimally invasive treatment, remain under investigation and see continuous progress. Current advances in these challenging areas are discussed in this review, which attempts to present an in-depth study of bezoars along with the well-established modalities and techniques.
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Li L, Xue B, Zhao Q, Xie HQ, Luan XR, Cui Q. Observation on the curative effect of long intestinal tube in the treatment of phytobezoar intestinal obstruction. Medicine (Baltimore) 2019; 98:e14861. [PMID: 30882686 PMCID: PMC6426573 DOI: 10.1097/md.0000000000014861] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/17/2022] Open
Abstract
The aim of the study was to observe the curative effect of long intestinal tube (LT) in the treatment of phytobezoar intestinal obstruction.We performed a retrospective study of patients with phytobezoar intestinal obstruction who underwent decompression with different tube insertion method. A total of 80 patients were collected and divided into nasogastric tube (NGT) group (n = 36) and LT group (n = 44) between August 2015 and August 2018 at our hospital. Univariate analysis was used to assess the clinical efficacy of 2 groups of patients.There were no significant differences in the mean age, sex ratio, and previous surgical history between the 2 groups. There were statistically significant differences between the 2 groups in terms of improvement time of clinical indications (4.2 ± 1.4 vs 2.5 ± 0.6 days; P = .008), liquid decompression amount on the first day of catheterization (870.4 ± 400.8 vs 1738.4 ± 460.2 mL; P = .000), transit operation rate (4/36 vs 0/44; P = .023), clinical cure rate (25/36 vs 40/44; P = .014), total treatment efficiency (32/36 vs 44/44; P = .023), and total hospitalization cost (3.25 ± 0.39 vs 2.07 ± 0.41 ¥ ten thousand; P = .000).The curative effect of LT in the treatment of phytobezoar intestinal obstruction is accurate and reliable, which can effectively improve the clinical symptoms of patients, comprehensively improve the non-surgical rate of intestinal obstruction treatment, reduce the total cost of hospitalization, and is worthy of promotion in clinical application.
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Affiliation(s)
- Liang Li
- Department of Gastrointestinal Surgery
| | - Bing Xue
- Department of Internal Medicine, Zibo Central Hospital of Shandong University, Zibo, Shandong, China
| | | | | | | | - Qing Cui
- Department of Gastrointestinal Surgery
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Murillo-Matamoros C, Ferri-Bataller R, Muñiz-Muñoz M, Calero-Paniagua I. Fitobezoar gástrico gigante secundario a estenosis pilórica tratado con Coca-Cola®: a propósito de un caso. Semergen 2019; 45:e3-e5. [DOI: 10.1016/j.semerg.2018.01.012] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/08/2017] [Revised: 01/11/2018] [Accepted: 01/22/2018] [Indexed: 10/27/2022]
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