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For: Trachootham D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov. 2009;8:579-591. [PMID: 19478820 DOI: 10.1038/nrd2803] [Citation(s) in RCA: 4160] [Impact Index Per Article: 260.0] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/08/2022]
Number Cited by Other Article(s)
1
Zhang L, Liu T, Chen M, Gao S, Staley CA, Yang L, Zhu L. Dual inhibition of oxidative phosphorylation and glycolysis using a hyaluronic acid nanoparticle NOX inhibitor enhanced response to radiotherapy in colorectal cancer. Biomaterials 2025;323:123437. [PMID: 40449083 DOI: 10.1016/j.biomaterials.2025.123437] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/13/2025] [Revised: 05/04/2025] [Accepted: 05/25/2025] [Indexed: 06/02/2025]
2
Gao Y, Song Z, Gan W, Zou X, Bai Y, Zhao X, Chen D, Qiao M. Selective and iron-independent ferroptosis in cancer cells induced by manipulation of mitochondrial fatty acid oxidation. Biomaterials 2025;320:123259. [PMID: 40112511 DOI: 10.1016/j.biomaterials.2025.123259] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/21/2024] [Revised: 02/20/2025] [Accepted: 03/14/2025] [Indexed: 03/22/2025]
3
Kavita, Adiani V, Sharma D, Mishra BB. Effect of gamma irradiation on different components of onion (Allium cepa) skin waste and enhancement of bioactive potentials. Food Chem 2025;484:144395. [PMID: 40286711 DOI: 10.1016/j.foodchem.2025.144395] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/18/2024] [Revised: 04/15/2025] [Accepted: 04/16/2025] [Indexed: 04/29/2025]
4
Rogalewicz B, Czylkowska A. Recent advances in the discovery of copper(II) complexes as potential anticancer drugs. Eur J Med Chem 2025;292:117702. [PMID: 40328033 DOI: 10.1016/j.ejmech.2025.117702] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/13/2025] [Revised: 04/13/2025] [Accepted: 04/27/2025] [Indexed: 05/08/2025]
5
Duan D, Yang X, Guo X, Li M, Jin X, Wang L, Xiao J, Wang X, Song P. Interaction of glaucocalyxin a with glutathione and thioredoxin reductase for triple-negative breast cancer treatment. Bioorg Chem 2025;161:108572. [PMID: 40359839 DOI: 10.1016/j.bioorg.2025.108572] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/05/2025] [Revised: 05/06/2025] [Accepted: 05/07/2025] [Indexed: 05/15/2025]
6
Verma N, Patel B, Sharma B, Kumari S, Hussain S, Patel HD, Priya K. Methyl Gallate: A Potent Bioactive Compound Promoting Osteogenic Differentiation by Regulating Runx2 and Cbfa1 in Osteoblastic Cell Lines. Biotechnol Appl Biochem 2025. [PMID: 40566992 DOI: 10.1002/bab.2784] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/02/2024] [Accepted: 05/03/2025] [Indexed: 06/28/2025]
7
Yang X, Yu L, Shao M, Yang H, Qi K, He G, Wang L, Kong D, Gu J, Xu X, Wang L. N6-methyladenosine-modified GPX2 impacts cancer cell stemness and TKI resistance through regulating of redox metabolism. Cell Death Dis 2025;16:458. [PMID: 40533443 PMCID: PMC12177039 DOI: 10.1038/s41419-025-07764-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/17/2024] [Revised: 05/13/2025] [Accepted: 06/03/2025] [Indexed: 06/22/2025]
8
Wang M, Xiao Y, Miao J, Zhang X, Liu M, Zhu L, Liu H, Shen X, Wang J, Xie B, Wang D. Oxidative Stress and Inflammation: Drivers of Tumorigenesis and Therapeutic Opportunities. Antioxidants (Basel) 2025;14:735. [PMID: 40563367 DOI: 10.3390/antiox14060735] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/07/2025] [Revised: 06/08/2025] [Accepted: 06/12/2025] [Indexed: 06/28/2025]  Open
9
Zhang J, Wang J, Wang X, Yan Z, Meng L, Zhang Y. Pterostilbene Reduces Cyclophosphamide-Induced Interstitial Cystitis by Facilitating Nrf2 Activation and Suppressing the NLRP3 Inflammasome Pathway. Int J Mol Sci 2025;26:5490. [PMID: 40564957 DOI: 10.3390/ijms26125490] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/29/2025] [Revised: 06/05/2025] [Accepted: 06/05/2025] [Indexed: 06/28/2025]  Open
10
Peng H, Ren J, Zhao Y, Fang X, Wang X, Liu C, Wan Z. Unraveling the Connection between PCOS and renal Complications: Current insights and Future Directions. Diabetes Res Clin Pract 2025;224:112235. [PMID: 40334925 DOI: 10.1016/j.diabres.2025.112235] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/11/2025] [Revised: 04/24/2025] [Accepted: 05/05/2025] [Indexed: 05/09/2025]
11
Abdalbari FH, Forgie BN, Zorychta E, Goyeneche AA, Noman ASM, Telleria CM. The gold complex auranofin sensitizes platinum resistant epithelial ovarian cancer cells to cisplatin. Biochem Biophys Rep 2025;42:101996. [PMID: 40230496 PMCID: PMC11995746 DOI: 10.1016/j.bbrep.2025.101996] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/21/2025] [Revised: 03/26/2025] [Accepted: 03/27/2025] [Indexed: 04/16/2025]  Open
12
Cornu M, Lemaitre T, Kieffer C, Voisin-Chiret AS. PROTAC 2.0: Expanding the frontiers of targeted protein degradation. Drug Discov Today 2025;30:104376. [PMID: 40348076 DOI: 10.1016/j.drudis.2025.104376] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/19/2025] [Revised: 04/24/2025] [Accepted: 05/02/2025] [Indexed: 05/14/2025]
13
Gencheva R, Coppo L, Arnér ESJ, Ren X. Selenium supplementation protects cancer cells from the oxidative stress and cytotoxicity induced by the combination of ascorbate and menadione sodium bisulfite. Free Radic Biol Med 2025;233:317-329. [PMID: 40180024 DOI: 10.1016/j.freeradbiomed.2025.03.049] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/10/2025] [Revised: 03/28/2025] [Accepted: 03/31/2025] [Indexed: 04/05/2025]
14
Mao L, Lu J, Wen X, Song Z, Sun C, Zhao Y, Huang F, Chen S, Jiang D, Che W, Zhong C, Yu C, Li K, Lu X, Shi J. Cuproptosis: mechanisms and nanotherapeutic strategies in cancer and beyond. Chem Soc Rev 2025. [PMID: 40433941 DOI: 10.1039/d5cs00083a] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/29/2025]
15
Li Z, Lu Y, Wang L, Shi L, Wang T. Reactive oxygen species-dependent nanomedicine therapeutic modalities for gastric cancer. NANOSCALE ADVANCES 2025;7:3210-3227. [PMID: 40308560 PMCID: PMC12038724 DOI: 10.1039/d5na00321k] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 04/06/2025] [Accepted: 04/15/2025] [Indexed: 05/02/2025]
16
Fu Y, Hao H, Fang Y, Sun S, Wen S, Liu Y, Tang J, Wang T, Wu M. Copper Peroxide-Ring Stabilized Bicelle Loaded with GSH-Responsive Derivative of Doxorubicin to Induce Amplified Cuproptosis. Adv Healthc Mater 2025:e2500691. [PMID: 40424095 DOI: 10.1002/adhm.202500691] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/07/2025] [Revised: 05/12/2025] [Indexed: 05/29/2025]
17
Jiang C, Chen Z, Yang R, Luogu Z, Ren Q, Hu H, Wang K, Li S, Deng C, Li M, Zheng L. Carbon-Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy. Adv Healthc Mater 2025:e2500369. [PMID: 40411849 DOI: 10.1002/adhm.202500369] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/22/2025] [Revised: 04/02/2025] [Indexed: 05/26/2025]
18
Schiele P, Japp AS, Stark R, Sattelberg JJ, Nikolaou C, Kornhuber G, Abbasi P, Ding N, Rosnev S, Meinke S, Mühle K, Loyal L, Braun J, Dingeldey M, Durlanik S, Matzmohr N, Ponikwicka-Tyszko D, Wolczynski S, Rahman NA, Taniuchi I, Schlickeiser S, Giesecke-Thiel C, Blankenstein T, Na IK, Thiel A, Frentsch M. CD8+ T cell-derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells. SCIENCE ADVANCES 2025;11:eadr9331. [PMID: 40397730 DOI: 10.1126/sciadv.adr9331] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 07/23/2024] [Accepted: 04/17/2025] [Indexed: 05/23/2025]
19
Chen D, Guo Z, Yao L, Sun Y, Dian Y, Zhao D, Ke Y, Zeng F, Zhang C, Deng G, Li L. Targeting oxidative stress-mediated regulated cell death as a vulnerability in cancer. Redox Biol 2025;84:103686. [PMID: 40424719 DOI: 10.1016/j.redox.2025.103686] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/01/2025] [Accepted: 05/17/2025] [Indexed: 05/29/2025]  Open
20
Ma C, Gao L, Song K, Gu B, Wang B, Yu Y, Wang X, Li X, Hu J, Pu W, Wang Y, Wang N, Lu D, Han Z, Chen H. Targeted Dual-Responsive Liposomes Co-Deliver Jolkinolide B and Ce6 to Synergistically Enhance the Photodynamic/Immunotherapy Efficacy in Gastric Cancer through the PANoptosis Pathway. ADVANCED SCIENCE (WEINHEIM, BADEN-WURTTEMBERG, GERMANY) 2025:e02289. [PMID: 40387011 DOI: 10.1002/advs.202502289] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 02/06/2025] [Revised: 04/20/2025] [Indexed: 05/20/2025]
21
Guo L, Yang Z, Dong H, Lai K, Fu H, Gong Y, Li S, Yue M, Liu Z. Systematic Investigation of Coordination Chemistry in Iridium(III) and Ruthenium(II) Complexes Derived from Pyridyl-Amine Ligands and Their Anticancer Evaluation. Inorg Chem 2025. [PMID: 40380917 DOI: 10.1021/acs.inorgchem.4c05599] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/19/2025]
22
Mei J, Tian HX, Zhang XY, Chen YS, Wang LY, Zhang Z, Zhang YL, Rong DC, Zeng J, Dong M, Gao Y, Yin JY, Wu HJ, Wang PY, Zhang W. Heme oxygenase 1 (HO-1) is a drug target for reversing cisplatin resistance in non-small cell lung cancer. J Adv Res 2025:S2090-1232(25)00347-9. [PMID: 40389113 DOI: 10.1016/j.jare.2025.05.033] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/13/2025] [Revised: 04/22/2025] [Accepted: 05/12/2025] [Indexed: 05/21/2025]  Open
23
Chintakindi J, Lahane GP, Dhar A, Mir A. Engineered Ti3C2(O,Cl) MXenes with dual functionalization: a new Frontier in targeted head and neck squamous cell carcinoma and breast adenocarcinoma. J Mater Chem B 2025. [PMID: 40375828 DOI: 10.1039/d5tb00302d] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/18/2025]
24
Hong R, Min S, Huang J, Zou M, Zhou D, Liang Y. High-dose vitamin C promotes mitochondrial biogenesis in HCT116 colorectal cancer cells by regulating the AMPK/PGC-1α signaling pathway. J Cancer Res Clin Oncol 2025;151:167. [PMID: 40372538 PMCID: PMC12081527 DOI: 10.1007/s00432-025-06211-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/27/2025] [Accepted: 04/23/2025] [Indexed: 05/16/2025]
25
Gao Q, Li P, Lu Z, Ma M, Zhang N, Lu Y, Yu J. Association of frailty and its trajectory with the risk of cancer: evidence from the China health and retirement longitudinal study (CHARLS). BMC Public Health 2025;25:1797. [PMID: 40375252 PMCID: PMC12080056 DOI: 10.1186/s12889-025-22959-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/23/2024] [Accepted: 04/28/2025] [Indexed: 05/18/2025]  Open
26
Li XY, Yu ZY, Li HJ, Yan DM, Yang C, Liu XZ. Biomarker identification associated with M2 tumor-associated macrophage infiltration in glioblastoma. Front Neurol 2025;16:1545608. [PMID: 40438577 PMCID: PMC12117037 DOI: 10.3389/fneur.2025.1545608] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/15/2024] [Accepted: 04/08/2025] [Indexed: 06/01/2025]  Open
27
Cini N, Atasoy Ö, Uyanikgil Y, Yaprak G, Erdoğan MA, Erbas O. Ceftriaxone has a neuroprotective effect in a whole-brain irradiation-induced neurotoxicity model by increasing GLT-1 and reducing oxidative stress. Strahlenther Onkol 2025:10.1007/s00066-025-02405-z. [PMID: 40353856 DOI: 10.1007/s00066-025-02405-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/16/2024] [Accepted: 03/30/2025] [Indexed: 05/14/2025]
28
Farmanbar A, Kneller R, Firouzi S. The Use of Mutational Signatures to Decipher the Inter-Relationship of Reactive Oxygen Species with Homologous Recombination and Non-Homologous End-Joining Deficiencies as Well as Their Effects on APOBEC Mutagenesis in Breast Cancer. Cancers (Basel) 2025;17:1627. [PMID: 40427126 PMCID: PMC12110613 DOI: 10.3390/cancers17101627] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/04/2025] [Revised: 05/02/2025] [Accepted: 05/08/2025] [Indexed: 05/29/2025]  Open
29
Błachnio-Zabielska AU, Sadowska P, Chlabicz U, Pogodzińska K, Le Stunff H, Laudański P, Szamatowicz J, Kuźmicki M. Differential Effects of Sphingolipids on Cell Death and Antioxidant Defenses in Type 1 and Type 2 Endometrial Cancer Cells. Int J Mol Sci 2025;26:4472. [PMID: 40429618 PMCID: PMC12110862 DOI: 10.3390/ijms26104472] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/24/2025] [Revised: 05/03/2025] [Accepted: 05/07/2025] [Indexed: 05/29/2025]  Open
30
Malarz K, Kuczak M, Rurka P, Rawicka P, Boguszewska-Czubara A, Jampilek J, Mularski J, Musiol R, Mrozek-Wilczkiewicz A. Unveiling the role of Ndrg1 gene on the oxidative stress induction behind the anticancer potential of styrylquinazoline derivatives. Sci Rep 2025;15:16081. [PMID: 40341822 PMCID: PMC12062220 DOI: 10.1038/s41598-025-99277-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/09/2024] [Accepted: 04/18/2025] [Indexed: 05/11/2025]  Open
31
Kawauchi D, Narita Y. The curse of blood-brain barrier and blood-tumor barrier in malignant brain tumor treatment. Int J Clin Oncol 2025:10.1007/s10147-025-02777-3. [PMID: 40338447 DOI: 10.1007/s10147-025-02777-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/10/2025] [Accepted: 04/24/2025] [Indexed: 05/09/2025]
32
Borbényi-Galambos K, Erdélyi K, Ditrói T, Jurányi EP, Szántó N, Szatmári R, Czikora Á, Schmidt EE, Garai D, Cserepes M, Liszkay G, Tóth E, Tóvári J, Nagy P. Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma. Cell Metab 2025;37:1171-1188.e9. [PMID: 40037361 DOI: 10.1016/j.cmet.2025.01.021] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/26/2023] [Revised: 12/13/2024] [Accepted: 01/22/2025] [Indexed: 03/06/2025]
33
Lin H, Sui H, Yu Y, Xie C, Shen Y, Cheng L, Wang J, Yu Y, Xie C, Cui R. Dihydrotanshinone I potentiates the anti-tumor activity of cisplatin by activating ROS-mediated ER stress through targeting HSPD1 in lung cancer cells. Eur J Pharmacol 2025;994:177378. [PMID: 39952584 DOI: 10.1016/j.ejphar.2025.177378] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/09/2024] [Revised: 01/20/2025] [Accepted: 02/11/2025] [Indexed: 02/17/2025]
34
Chakraborty S, Choudhuri A, Mishra A, Sengupta R. S-nitrosylation and S-glutathionylation: Lying at the forefront of redox dichotomy or a visible synergism? Biochem Biophys Res Commun 2025;761:151734. [PMID: 40179738 DOI: 10.1016/j.bbrc.2025.151734] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/22/2024] [Revised: 03/06/2025] [Accepted: 03/29/2025] [Indexed: 04/05/2025]
35
Tang S, Li J, Tian W, Feng Y, Deng Y, Tan Z, Han Z, He H, Wu Y, Huang C, Ning K, Liu F, Luo H, Cai S, Ye J, Zhong W. Characterization of the Biochemical Recurrence Prediction Ability and Progression Correlation of Peroxiredoxins Family in Prostate Cancer Based on Integrating Single-Cell RNA-Seq and Bulk RNA-Seq Cohorts. Cancer Med 2025;14:e70855. [PMID: 40281661 PMCID: PMC12031674 DOI: 10.1002/cam4.70855] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/11/2024] [Revised: 03/25/2025] [Accepted: 03/26/2025] [Indexed: 04/29/2025]  Open
36
Zhu X, Yuan F, Sun Q, Yang C, Jiang H, Xiang X, Zhang X, Sun Z, Wei Y, Chen Q, Cai L. N-acetylcysteine remodels the tumor microenvironment of primary and recurrent mouse glioblastoma. J Neurooncol 2025;173:131-145. [PMID: 39954037 DOI: 10.1007/s11060-025-04971-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/11/2024] [Accepted: 02/08/2025] [Indexed: 02/17/2025]
37
Tan J, Ding B, Chen H, Meng Q, Li J, Zhang W, Yang Z, Ma X, Han D, Yang M, Zheng P, Ma P, Lin J. Gallium-Magnesium Layered Double Hydroxide for Elevated Tumor Immunotherapy Through Multi-Network Synergistic Regulation. ADVANCED MATERIALS (DEERFIELD BEACH, FLA.) 2025;37:e2501256. [PMID: 40190140 DOI: 10.1002/adma.202501256] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 01/18/2025] [Revised: 03/12/2025] [Indexed: 05/28/2025]
38
Liu Y, Zhang X, Zhang X, Wang G, Li X, Xing S, Cao C, Li Y, Han L, Wang S. Histone deacetylase inhibiting nanoprodrugs for enhanced chemodynamic therapy through multistage downregulating glutathione. Int J Biol Macromol 2025;305:141184. [PMID: 39971061 DOI: 10.1016/j.ijbiomac.2025.141184] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/02/2024] [Revised: 01/26/2025] [Accepted: 02/15/2025] [Indexed: 02/21/2025]
39
Wang S, Yang J, Zhen C, Wang H, Shang P. Electromagnetic fields regulate iron metabolism: From mechanisms to applications. J Adv Res 2025:S2090-1232(25)00288-7. [PMID: 40311754 DOI: 10.1016/j.jare.2025.04.044] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/22/2024] [Revised: 04/06/2025] [Accepted: 04/28/2025] [Indexed: 05/03/2025]  Open
40
Świderska-Kołacz G, Madej M, Zmorzynski S, Styk W, Surowiec I, Witek B, Wojciechowska A, Czerwik-Marcinkowska J, Nowakowska A. Effects of bortezomib on intracellular antioxidant and apoptosis in HepG2cells. PeerJ 2025;13:e19235. [PMID: 40313384 PMCID: PMC12045286 DOI: 10.7717/peerj.19235] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/03/2024] [Accepted: 03/10/2025] [Indexed: 05/03/2025]  Open
41
Li C, Cheng H, Zhuang Z, Cao F, Liu H, Zhao L, Rizvi SFA, Wang K, Yang L, Lu X, Zheng Y, Zhang Y, He P, Mao J, Wen X, Zhang L, Jiang L, Lin J, Li D, Chu C, Zeng Y, Lu Z, Liu C, Thompson EW, Chen Z, Wang P, Liu G. FlexiPlasma Microcatheter-Embolic Material (FPM-EM) Platform: A Non-Inflammatory Pyroptosis Strategy for Precision Hepatocellular Carcinoma Therapy. SMALL METHODS 2025:e2500231. [PMID: 40285389 DOI: 10.1002/smtd.202500231] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 02/05/2025] [Revised: 04/03/2025] [Indexed: 04/29/2025]
42
Qu Y, Ma Q, Wang C, Zhang L, Feng H, Lai S. Pulsatilla Powder Ameliorates Damp-Heat Diarrhea in Piglets Through the Regulation of Intestinal Mucosal Barrier and the Pentose Phosphate Pathway Involving G6PD and NOX. Vet Sci 2025;12:403. [PMID: 40431496 PMCID: PMC12116046 DOI: 10.3390/vetsci12050403] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/10/2025] [Revised: 04/15/2025] [Accepted: 04/19/2025] [Indexed: 05/29/2025]  Open
43
Yeon Chae S, Jang SY, Kim J, Hwang S, Malani D, Kallioniemi O, Yun SG, Kim JS, Kim HI. Mechanisms of chemotherapy failure in refractory/relapsed acute myeloid leukemia: the role of cytarabine resistance and mitochondrial metabolism. Cell Death Dis 2025;16:331. [PMID: 40268906 PMCID: PMC12019594 DOI: 10.1038/s41419-025-07653-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/18/2024] [Revised: 04/05/2025] [Accepted: 04/09/2025] [Indexed: 04/25/2025]
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Park MN, Kim M, Lee S, Kang S, Ahn CH, Tallei TE, Kim W, Kim B. Targeting Redox Signaling Through Exosomal MicroRNA: Insights into Tumor Microenvironment and Precision Oncology. Antioxidants (Basel) 2025;14:501. [PMID: 40427384 PMCID: PMC12108341 DOI: 10.3390/antiox14050501] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/27/2025] [Revised: 04/18/2025] [Accepted: 04/20/2025] [Indexed: 05/29/2025]  Open
45
Bhattacharyya T, Das P, Ansari A, Mohan AA, Chandra Y, Narayan KP, Banerjee R. Glucocorticoid Receptor-Targeted Nanoliposome for STAT3 Inhibition-Led Myeloid-Derived Suppressor Cell Modulation and Efficient Colon Cancer Treatment. ACS APPLIED BIO MATERIALS 2025;8:3185-3204. [PMID: 40162961 DOI: 10.1021/acsabm.5c00002] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/02/2025]
46
Ding M, Chen H, He L, Wang Z, Zhao X, Sun P, Mei Q, Li D, Fan Q. NIR-II D-A-D-Type Small-Molecule Coordination with Carboxylatopillar[5]Arene: a Multifunctional Phototheranostic for Low-Temperature NIR-II Photothermal/Platinum-Based/Chemodynamic Combination Cancer Immunotherapy. SMALL (WEINHEIM AN DER BERGSTRASSE, GERMANY) 2025:e2501903. [PMID: 40255101 DOI: 10.1002/smll.202501903] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 02/26/2025] [Revised: 04/03/2025] [Indexed: 04/22/2025]
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Feng Z, Ou L, Li H, Hao Y, Wei R, Zhang G, Yao M. Unveiling the therapeutic potential of HZQYF: exploring the inhibitory impact of a clinical herbal formula on gastric cancer through network pharmacology and transcript analysis. BMC Complement Med Ther 2025;25:142. [PMID: 40247271 PMCID: PMC12004866 DOI: 10.1186/s12906-025-04871-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/28/2024] [Accepted: 03/27/2025] [Indexed: 04/19/2025]  Open
48
Hayashi M, Nakamura K, Harada S, Tanaka M, Kobayashi A, Saito H, Tsuji T, Yamamoto D, Moriyama H, Kinoshita J, Inaki N. GLUT1 inhibition by BAY-876 induces metabolic changes and cell death in human colorectal cancer cells. BMC Cancer 2025;25:716. [PMID: 40247224 PMCID: PMC12004878 DOI: 10.1186/s12885-025-14141-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/29/2024] [Accepted: 04/11/2025] [Indexed: 04/19/2025]  Open
49
Gao X, Li Y, Xu H, Ni S, Pan H, Ma C, Zhao X, Zhang H. Xanthatin induces apoptosis through ROS-mediated c-FLIP inhibition in human retinoblastoma cells. Front Med (Lausanne) 2025;12:1554934. [PMID: 40309730 PMCID: PMC12041067 DOI: 10.3389/fmed.2025.1554934] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/03/2025] [Accepted: 03/24/2025] [Indexed: 05/02/2025]  Open
50
Chen H, Wang M, Yang Q, Liu J, Liu F, Zhu X, Huang S, Yin P, Wang X, Li H, Zhang Y, Liu M, Wei M, Yao S, Liu Y. Multifunctional porphyrinic metal-organic framework-based nanoplatform regulating reactive oxygen species achieves efficient imaging-guided cascaded nanocatalytic therapy. J Colloid Interface Sci 2025;684:423-438. [PMID: 39799625 DOI: 10.1016/j.jcis.2025.01.041] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/22/2024] [Revised: 01/05/2025] [Accepted: 01/06/2025] [Indexed: 01/15/2025]
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