For: | Lu LG, Zeng MD, Mao YM, Li JQ, Wan MB, Li CZ, Chen CW, Fu QC, Wang JY, She WM, Cai X, Ye J, Zhou XQ, Wang H, Wu SM, Tang MF, Zhu JS, Chen WX, Zhang HQ. Oxymatrine therapy for chronic hepatitis B: A randomized double-blind and placebo-controlled multi-center trial. World J Gastroenterol 2003; 9(11): 2480-2483 [PMID: 14606080 DOI: 10.3748/wjg.v9.i11.2480] |
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URL: | https://www.wjgnet.com/1007-9327/full/v9/i11/2480.htm |
Number | Citing Articles |
1 |
HUI CHEN, JIANHONG ZHANG, JIANG LUO, FUJI LAI, ZHAOHONG WANG, HONGFEI TONG, DIAN LU, HEQI BU, RIYUAN ZHANG, SHENGZHANG LIN. Antiangiogenic effects of oxymatrine on pancreatic cancer by inhibition of the NF-κB-mediated VEGF signaling pathway. Oncology Reports 2013; 30(2): 589 doi: 10.3892/or.2013.2529
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2 |
Yun Chen, Ziyou Qi, Baojun Qiao, Zhanyun Lv, Yanlei Hao, Hongfang Li. Oxymatrine can attenuate pathological deficits of Alzheimer's disease mice through regulation of neuroinflammation. Journal of Neuroimmunology 2019; 334: 576978 doi: 10.1016/j.jneuroim.2019.576978
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3 |
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4 |
Yang Li, Guan Wang, Jie Liu, Liang Ouyang. Quinolizidine alkaloids derivatives from Sophora alopecuroides Linn: Bioactivities, structure-activity relationships and preliminary molecular mechanisms. European Journal of Medicinal Chemistry 2020; 188: 111972 doi: 10.1016/j.ejmech.2019.111972
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5 |
Yu-Ping Wang, Wei Zhao, Rong Xue, Zhen-Xian Zhou, Fei Liu, Yan-Xing Han, Gang Ren, Zong-Gen Peng, Shan Cen, Hong-Shan Chen, Yu-Huan Li, Jian-Dong Jiang. Oxymatrine inhibits hepatitis B infection with an advantage of overcoming drug-resistance. Antiviral Research 2011; 89(3): 227 doi: 10.1016/j.antiviral.2011.01.005
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6 |
Xiaohong Liu, Lei Li, Jin Sun, Yinghua Sun, Tianhong Zhang, Dawei Chen, Zhonggui He. Development and Validation of LC Coupled with SPE for Simultaneous Determination of Lamivudine, Oxymatrine and its Active Metabolite Matrine in Dog Plasma. Chromatographia 2006; 63(9-10): 483 doi: 10.1365/s10337-006-0773-2
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7 |
Yan-hui Sun, Xiao-yuan Zhang, Wei-qun Xie, Guang-jian Liu, Xi-xin He, Ya-li Huang, Guang-xian Zhang, Jian Wang, Zao-yuan Kuang, Ren Zhang. Identification of UQCRB as an oxymatrine recognizing protein using a T7 phage display screen. Journal of Ethnopharmacology 2016; 193: 133 doi: 10.1016/j.jep.2016.08.007
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8 |
Xuanbin Wang, Ning Wang, Fan Cheung, Lixing Lao, Charlie Li, Yibin Feng. Chinese medicines for prevention and treatment of human hepatocellular carcinoma: current progress on pharmacological actions and mechanisms. Journal of Integrative Medicine 2015; 13(3): 142 doi: 10.1016/S2095-4964(15)60171-6
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9 |
Hongguang Fan, Litao Li, Xiangjian Zhang, Ying Liu, Chenhui Yang, Yi Yang, Jing Yin. Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia. Mediators of Inflammation 2009; 2009: 1 doi: 10.1155/2009/704706
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10 |
H. Zhou, H.-J. Shi, J. Yang, W.-G. Chen, L. Xia, H.-B. Song, K.-P. Bo, W. Ma. Efficacy of oxymatrine for treatment and relapse suppression of severe plaque psoriasis: results from a single-blinded randomized controlled clinical trial. British Journal of Dermatology 2017; 176(6): 1446 doi: 10.1111/bjd.15316
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11 |
Zhengtao Yang, Ronglan Yin, Yunfeng Cong, Zhanqing Yang, Ershun Zhou, Zhengkai Wei, Zhicheng Liu, Yongguo Cao, Naisheng Zhang. Oxymatrine Lightened the Inflammatory Response of LPS-Induced Mastitis in Mice Through Affecting NF-κB and MAPKs Signaling Pathways. Inflammation 2014; 37(6): 2047 doi: 10.1007/s10753-014-9937-7
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12 |
Jian-Ping Dai, Qian-Wen Wang, Yun Su, Li-Ming Gu, Hui-Xiong Deng, Xiao-Xuan Chen, Wei-Zhong Li, Kang-Sheng Li. Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-κB Pathways. International Journal of Molecular Sciences 2018; 19(4): 965 doi: 10.3390/ijms19040965
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13 |
Rachel B. Wilson, Jason J. Lee, J. Geoffrey Pickering, Nica M. Borradaile. Regenerative Nephrology. 2022; : 419 doi: 10.1016/B978-0-12-823318-4.00027-5
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14 |
Jun Liu, Yazhou Yao, Huifang Ding, Renan Chen. Oxymatrine triggers apoptosis by regulating Bcl-2 family proteins and activating caspase-3/caspase-9 pathway in human leukemia HL-60 cells. Tumor Biology 2014; 35(6): 5409 doi: 10.1007/s13277-014-1705-7
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15 |
Jinna Cao, Jukui Sun, Xiaoyu Wang, Xinran Li, Yingjie Deng. N-Trimethyl chitosan-coated multivesicular liposomes for oxymatrine oral delivery. Drug Development and Industrial Pharmacy 2009; 35(11): 1339 doi: 10.3109/03639040902902427
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16 |
Lirong Liu, Yuanyuan Wang, Rui Yan, Shuang Li, Mingjun Shi, Ying Xiao, Bing Guo, Wing-Kin Syn. Oxymatrine Inhibits Renal Tubular EMT Induced by High Glucose via Upregulation of SnoN and Inhibition of TGF-β1/Smad Signaling Pathway. PLOS ONE 2016; 11(3): e0151986 doi: 10.1371/journal.pone.0151986
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17 |
Dina L Halegoua-De Marzio, Jonathan M Fenkel. Complementary and alternative medications in hepatitis C infection. World Journal of Hepatology 2014; 6(1): 9-16 doi: 10.4254/wjh.v6.i1.9
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18 |
Maria Ponticelli, Maria Laura Bellone, Valentina Parisi, Annamaria Iannuzzi, Alessandra Braca, Nunziatina de Tommasi, Daniela Russo, Annalisa Sileo, Paola Quaranta, Giulia Freer, Mauro Pistello, Luigi Milella. Specialized metabolites from plants as a source of new multi-target antiviral drugs: a systematic review. Phytochemistry Reviews 2023; 22(3): 615 doi: 10.1007/s11101-023-09855-2
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19 |
Omonike O. Ogbole, Temitayo A. Ajayi, Oluwatoyin A. Odeku. Herbal Drugs for the Management of Infectious Diseases. 2022; : 389 doi: 10.1002/9781119818779.ch14
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20 |
S. Du, Y. Deng. Studies on the Encapsulation of Oxymatrine into Liposomes by Ethanol Injection and pH Gradient Method. Drug Development and Industrial Pharmacy 2006; 32(7): 791 doi: 10.1080/03639040600760556
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21 |
Ning Yao, Xin Wang. In vitro Immunomodulatory Activity of Oxymatrine on Toll-Like Receptor 9 Signal Pathway in Chronic Hepatitis B. The American Journal of Chinese Medicine 2014; 42(06): 1399 doi: 10.1142/S0192415X14500888
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22 |
Qing Zhao, Xia Ren, Min Chen, Shi-Jun Yue, Meng-Qi Zhang, Kai-Xian Chen, Yue-Wei Guo, Chang-Lun Shao, Chang-Yun Wang. Effects of traditional Chinese medicine formula Le-Cao-Shi on hepatitis B: In vivo and in vitro studies. Journal of Ethnopharmacology 2019; 244: 112132 doi: 10.1016/j.jep.2019.112132
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23 |
Jia-Xin Chen, Hong-Hui Shen, Ming Niu, Yu-Ming Guo, Xiao-Qiong Liu, Yan-Zhong Han, Ya-Ming Zhang, Yan-Ling Zhao, Bing-Ke Bai, Wen-Jun Zhou, Xiao-He Xiao. Anti-hepatitis B virus effect of matrine-type alkaloid and involvement of p38 mitogen-activated protein kinase and tumor necrosis factor receptor-associated factor 6. Virus Research 2016; 215: 104 doi: 10.1016/j.virusres.2015.12.005
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24 |
Zhenbao Li, Lei Shang, Chang Liu, Panqin Ma, Chunnuan Wu, Wenjuan Zhang, Yinghua Sun, Yongjun Wang, Xiaohong Liu, Jin Sun. Evaluation of pharmacokinetics underlies the collaborated usage of lamivudine and oxymatrine in beagle dogs. Asian Journal of Pharmaceutical Sciences 2016; 11(5): 641 doi: 10.1016/j.ajps.2016.02.007
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25 |
Jianhong Yang, Guidong Dai, Yanhui Hou, Zhihua Song, Fang Wang, Gangjian Ji, Jianhai Chen. Quantification of oxymatrine in rat plasma by UPLC-MS/MS to support the pharmacokinetic analyses of oxymatrine-loaded polymersomes. Anal. Methods 2014; 6(6): 1811 doi: 10.1039/C3AY42294A
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26 |
Xiao-Xia Liu, Shi-Qing Sun, Yu-Jie Wang, Wei Xu, Yi-Fang Wang, Daeui Park, Hai-Meng Zhou, Hong-Yan Han. Kinetics and Computational Docking Studies on the Inhibition of Tyrosinase Induced by Oxymatrine. Applied Biochemistry and Biotechnology 2013; 169(1): 145 doi: 10.1007/s12010-012-9960-9
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27 |
Huijuan Shi, Dongmei Chen, Jiawei Si, Qian Zou, Yatao Guo, Jiayu Yu, Cheng Li, Fang Wang. Efficacy and Safety of Oxymatrine in the Treatment of Patients with Erythrodermic Psoriasis. Dermatology and Therapy 2024; 14(6): 1659 doi: 10.1007/s13555-024-01181-5
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28 |
H.‐J. Shi, H. Zhou, A.‐L. Ma, L. Wang, Q. Gao, N. Zhang, H.‐B. Song, K.‐P. Bo, W. Ma. Oxymatrine therapy inhibited epidermal cell proliferation and apoptosis in severe plaque psoriasis. British Journal of Dermatology 2019; 181(5): 1028 doi: 10.1111/bjd.17852
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29 |
Konstantinos Anastassakis. Androgenetic Alopecia From A to Z. 2022; : 471 doi: 10.1007/978-3-031-08057-9_55
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30 |
Na-Na Du, Xin Li, Yu-Ping Wang, Fei Liu, Yan-Xin Liu, Chun-Xin Li, Zong-Gen Peng, Li-Mei Gao, Jian-Dong Jiang, Dan-Qing Song. Synthesis, structure−activity relationship and biological evaluation of novel N-substituted matrinic acid derivatives as host heat-stress cognate 70 (Hsc70) down-regulators. Bioorganic & Medicinal Chemistry Letters 2011; 21(16): 4732 doi: 10.1016/j.bmcl.2011.06.071
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31 |
Cun-Bao Ding, Jing-Pu Zhang, Ye Zhao, Zong-Gen Peng, Dan-Qing Song, Jian-Dong Jiang, Ashok Chauhan. Zebrafish as a Potential Model Organism for Drug Test Against Hepatitis C Virus. PLoS ONE 2011; 6(8): e22921 doi: 10.1371/journal.pone.0022921
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32 |
Yu-Ping Wang, Fei Liu, Hong-Wei He, Yan-Xin Han, Zong-Gen Peng, Bao-Wei Li, Xue-Fu You, Dan-Qing Song, Zhuo-Rong Li, Li-Yan Yu, Shan Cen, Bin Hong, Chen-Heng Sun, Li-Xun Zhao, Barry Kreiswirth, David Perlin, Rong-Guang Shao, Jian-Dong Jiang. Heat Stress Cognate 70 Host Protein as a Potential Drug Target against Drug Resistance in Hepatitis B Virus. Antimicrobial Agents and Chemotherapy 2010; 54(5): 2070 doi: 10.1128/AAC.01764-09
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33 |
Xia Liao, Yang Bu, Qingan Jia. Traditional Chinese medicine as supportive care for the management of liver cancer: Past, present, and future. Genes & Diseases 2020; 7(3): 370 doi: 10.1016/j.gendis.2019.10.016
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34 |
Ali Navi, Hemanshu Patel, Sidney Shaw, Daryll Baker, Janice Tsui. Therapeutic role of toll-like receptor modification in cardiovascular dysfunction. Vascular Pharmacology 2013; 58(3): 231 doi: 10.1016/j.vph.2012.10.001
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35 |
Yunzhi Zhang, Jinwei Ren, Wenzhao Wang, Baosong Chen, Erwei Li, Sanfeng Chen. Siderophore and indolic acid production by Paenibacillus triticisoli BJ-18 and their plant growth-promoting and antimicrobe abilities. PeerJ 2020; 8: e9403 doi: 10.7717/peerj.9403
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36 |
Ahmed Sadek, Ahmed M. Abd El Hady, Hammam Olfat, Afaf A. Abd El Hady, Wafaa Wafy, Moushira Zaki, Eman R. Youness. Effect of ozone gas on viral kinetics and liver histopathology in hepatitis C patients. Journal of Complementary and Integrative Medicine 2024; 21(1): 131 doi: 10.1515/jcim-2023-0239
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37 |
Ning Liang, De Zhao Kong, Si Si Ma, Chun Li Lu, Ming Yang, Lu Da Feng, Chen Shen, Ruo Han Diao, Ling Jun Cui, Xing Yu Lu, Dimitrinka Nikolova, Janus C Jakobsen, Christian Gluud, Jian Ping Liu. Radix Sophorae flavescentis versus no intervention or placebo for chronic hepatitis B. Cochrane Database of Systematic Reviews 2019; doi: 10.1002/14651858.CD013089.pub2
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38 |
Liver targeting effect of vinegar-baked Radix Bupleuri on oxymatrine in mice. 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW) 2011; : 740 doi: 10.1109/BIBMW.2011.6112462
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39 |
Li Hua Huang, Yun Ming Zhong, Xiao Hong Xiong, Mei Feng Cen, Xuan Ge Cheng, Gui Xiang Wang, Ji Sheng Chen, Su Jun Wang. The Disposition of Oxymatrine in the Vascularly Perfused Rat Intestine-Liver Preparation and Its Metabolism in Rat Liver Microsomes. Journal of Pharmaceutical Sciences 2016; 105(2): 897 doi: 10.1016/j.xphs.2015.11.012
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40 |
Li-Mei Gao, Yan-Xing Han, Yu-Ping Wang, Yu-Huan Li, Yong-Qiang Shan, Xin Li, Zong-Gen Peng, Chong-Wen Bi, Tian Zhang, Na-Na Du, Jian-Dong Jiang, Dan-Qing Song. Design and Synthesis of Oxymatrine Analogues Overcoming Drug Resistance in Hepatitis B Virus through Targeting Host Heat Stress Cognate 70. Journal of Medicinal Chemistry 2011; 54(3): 869 doi: 10.1021/jm101325h
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41 |
Dheeraj Singh Chauhan, Shailendra Yadav, M.A. Quraishi. Natural products as environmentally safe and green approach to combat Covid-19. Current Research in Green and Sustainable Chemistry 2021; 4: 100114 doi: 10.1016/j.crgsc.2021.100114
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42 |
Zhiqiang Zhang, Yanqing Wang, Ming Dong, Jianchun Cui, Daqing Rong, Qi Dong. Oxymatrine Ameliorates l-Arginine-Induced Acute Pancreatitis in Rats. Inflammation 2012; 35(2): 605 doi: 10.1007/s10753-011-9352-2
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43 |
Wei-jiang Song, Jing Luo, Tong Wu, Shu-kun Yao. Oral oxymatrine preparation for chronic hepatitis B: A systematic review of randomized controlled trials. Chinese Journal of Integrative Medicine 2016; 22(2): 141 doi: 10.1007/s11655-015-2143-0
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44 |
Junyu Wu, Guoyi Tang, Chien-Shan Cheng, Ranna Yeerken, Yau-Tuen Chan, Zhiwen Fu, Yi-Chao Zheng, Yibin Feng, Ning Wang. Traditional Chinese medicine for the treatment of cancers of hepatobiliary system: from clinical evidence to drug discovery. Molecular Cancer 2024; 23(1) doi: 10.1186/s12943-024-02136-2
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45 |
Li-Peng Qiu, Ke-Ping Chen. Anti-HBV agents derived from botanical origin. Fitoterapia 2013; 84: 140 doi: 10.1016/j.fitote.2012.11.003
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46 |
Xiuxiu Sang, Ruilin Wang, Yanzhong Han, Cong'en Zhang, Honghui Shen, Zhirui Yang, Yin Xiong, Huimin Liu, Shijing Liu, Ruisheng Li, Ruichuang Yang, Jiabo Wang, Xuejun Wang, Zhaofang Bai, Xiaohe Xiao. T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model. Acta Pharmaceutica Sinica B 2017; 7(3): 311 doi: 10.1016/j.apsb.2017.02.005
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47 |
Xiufeng Liu, Feng Xia, Yue Chen, Huichuan Sun, Zhengqiang Yang, Bo Chen, Ming Zhao, Xinyu Bi, Tao Peng, Aizier Ainiwaer, Zhiwen Luo, Fusheng Wang, Yinying Lu. Chinese expert consensus on refined diagnosis, treatment, and management of advanced primary liver cancer (2023 edition). Liver Research 2024; 8(2): 61 doi: 10.1016/j.livres.2024.05.001
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48 |
Anwar Parvez, Aparajita Das, Ashik Mahmud, Partha Biswas, Md Hasibul Hasan, Sadia Jannat Tauhida, Md. Saqline Mostaq, Md. Mahedi Hasan Nahid, Farzana Ansari, Saikat Fakir, Mohammad Nurul Amin. Mechanistic insights of clinically proven natural products in the treatment of hepatitis B focusing on clinical evidence and pathways. Clinical Traditional Medicine and Pharmacology 2024; : 200183 doi: 10.1016/j.ctmp.2024.200183
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49 |
Tim Shaw, Stephen Locarnini. Hepatitis Prevention and Treatment. 2004; : 203 doi: 10.1007/978-3-0348-7903-3_11
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50 |
Li-juan Shi, Lei Shi, Guang-yao Song, He-fang Zhang, Zhi-juan Hu, Chao Wang, Dong-hui Zhang. Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding transcription factor 1 (Srebf1) and activation of peroxisome proliferator activated receptor alpha (Pparα). European Journal of Pharmacology 2013; 714(1-3): 89 doi: 10.1016/j.ejphar.2013.06.013
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51 |
Xin-Jiang Ying, Bin Jin, Xin-Wei Chen, Jin Xie, Hong-Ming Xu, Pin Dong. Oxymatrine DownregulatesHPV16E7Expression and Inhibits Cell Proliferation in Laryngeal Squamous Cell Carcinoma Hep-2 Cells In Vitro. BioMed Research International 2015; 2015: 1 doi: 10.1155/2015/150390
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52 |
Ze Lin, Chang‐Fa Huang, Xiao‐Shan Liu, Jikai Jiang. In Vitro Anti‐Tumour Activities of Quinolizidine Alkaloids Derived from Sophora Flavescens Ait. Basic & Clinical Pharmacology & Toxicology 2011; 108(5): 304 doi: 10.1111/j.1742-7843.2010.00653.x
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53 |
WW Lu, R Zhang, JS Zhu, LQ Xia, J Zhang. Oxymatrine and cancer therapy. European Journal of Inflammation 2015; 13(3): 148 doi: 10.1177/1721727X15613911
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54 |
Lei Kang, Jiaqian Pan, Jiaofen Wu, Jiali Hu, Qian Sun, Jing Tang. Anti-HBV Drugs: Progress, Unmet Needs, and New Hope. Viruses 2015; 7(9): 4960 doi: 10.3390/v7092854
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55 |
Qing Zhao, Shu-Yue Song, Yu-Qi Zhang, Xia Ren, Peng Zhang, Xin Li, Xiu-Mei Fu, Chang-Yun Wang. The underlying mechanisms of anti-hepatitis B effects of formula Le-Cao-Shi and its single herbs by network pharmacology and gut microbiota analysis. Biomedicine & Pharmacotherapy 2022; 148: 112692 doi: 10.1016/j.biopha.2022.112692
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56 |
Meifeng Liu, Sha Jin, Hao Yan, Song Du. Effect of oxymatrine HSPC liposomes on improving bioavailability, liver target distribution and hepatoprotective activity of oxymatrine. European Journal of Pharmaceutical Sciences 2017; 104: 212 doi: 10.1016/j.ejps.2017.03.048
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57 |
Javier Rivera Guzman, Ja Seol Koo, Jason R. Goldsmith, Marcus Mühlbauer, Acharan Narula, Christian Jobin. Oxymatrine Prevents NF-κB Nuclear Translocation And Ameliorates Acute Intestinal Inflammation. Scientific Reports 2013; 3(1) doi: 10.1038/srep01629
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58 |
Min He, Yu Wu, Mengmeng Wang, Wenwen Chen, Weian Yuan, Jian Jiang. The Clinical Value of Oxymatrine in Preventing Lamivudine Induced YMDD Mutation: A Meta-Analysis. Evidence-Based Complementary and Alternative Medicine 2015; 2015: 1 doi: 10.1155/2015/971616
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59 |
Ruizhou Wang, Xinxin Deng, Qixia Gao, Xiuli Wu, Lu Han, Xiaojuan Gao, Shipeng Zhao, Weibin Chen, Rongrong Zhou, Zhiyong Li, Changcai Bai. Sophora alopecuroides L.: An ethnopharmacological, phytochemical, and pharmacological review. Journal of Ethnopharmacology 2020; 248: 112172 doi: 10.1016/j.jep.2019.112172
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