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For: Xu JW, Gong J, Chang XM, Luo JY, Dong L, Hao ZM, Jia A, Xu GP. Estrogen reduces CCL4- induced liver fibrosis in rats. World J Gastroenterol 2002; 8(5): 883-887 [PMID: 12378635 DOI: 10.3748/wjg.v8.i5.883]
URL: https://www.wjgnet.com/1007-9327/full/v8/i5/883.htm
Number Citing Articles
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Shotaro Nishimura, Akifumi Teshima, Fuminori Kawabata, Shoji Tabata. Estradiol inhibits hepatic stellate cell area and collagen synthesis in the chicken liverAnimal Science Journal 2017; 88(11) doi: 10.1111/asj.12830
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Lujain Bader Eddin, Amar Mahgoub, Saeeda Almarzooqi, Ernest Adeghate, Sandeep B. Subramanya, Shreesh Ojha. β-Caryophyllene Ameliorates Thioacetamide-Induced Liver Fibrosis in Rats: A Preventative ApproachInternational Journal of Molecular Sciences 2025; 26(17) doi: 10.3390/ijms26178493
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Dino Šisl, Darja Flegar, Maša Filipović, Petra Turčić, Pavao Planinić, Alan Šućur, Nataša Kovačić, Danka Grčević, Tomislav Kelava. Tamoxifen Ameliorates Cholestatic Liver Fibrosis in Mice: Upregulation of TGFβ and IL6 Is a Potential Protective MechanismBiomedicines 2022; 10(5) doi: 10.3390/biomedicines10051209
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Tan Deng, Jing Liu, Mengmeng Zhang, Yaxin Wang, Guannan Zhu, Jiajia Wang. Inhibition effect of phytoestrogen calycosin on TGF-β1-induced hepatic stellate cell activation, proliferation, and migration via estrogen receptor βCanadian Journal of Physiology and Pharmacology 2018; 96(12) doi: 10.1139/cjpp-2018-0474
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M. K. Han, S. Murray, C. D. Fell, K. R. Flaherty, G. B. Toews, J. Myers, T. V. Colby, W. D. Travis, E. A. Kazerooni, B. H. Gross, F. J. Martinez. Sex differences in physiological progression of idiopathic pulmonary fibrosisEuropean Respiratory Journal 2008; 31(6) doi: 10.1183/09031936.00165207
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Paola Nasta, Ivana Maida, Anna Maria Cattelan, Emanuele Pontali, Elena Angeli, Mariarosaria Giralda, Gabriella Verucchi, Antonietta Caputo, Claudio Iannacone, Massimo Puoti, Giampiero Carosi. Effect of Aging, Glucose Level, and HIV Viral Load on Response to Treatment with Pegylated Interferon Plus Ribavirin in HIV/HCV Co-Infected WomenJournal of Women's Health 2015; 24(2) doi: 10.1089/jwh.2014.4796
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Sung Eun Kim, Ji-Song Min, Saemi Lee, Dong-Yun Lee, DooSeok Choi. Different effects of menopausal hormone therapy on non-alcoholic fatty liver disease based on the route of estrogen administrationScientific Reports 2023; 13(1) doi: 10.1038/s41598-023-42788-6
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Yan-Jun Luo, Jie-Ping Yu, Zhao-Hong Shi, Li Wang. Ginkgo biloba extract reverses CCl<sub>4</sub>&ndash;induced liver fibrosis in ratsWorld Journal of Gastroenterology 2004; 10(7): 1037-1042 doi: 10.3748/wjg.v10.i7.1037
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Swathi Balaji, Xiaoyu Dong, Hui Li, Yuhao Zhang, Emily Steen, Krithika Lingappan. Sex-specific differences in primary neonatal murine lung fibroblasts exposed to hyperoxia in vitro: implications for bronchopulmonary dysplasiaPhysiological Genomics 2018; 50(11) doi: 10.1152/physiolgenomics.00075.2018
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Qing-Hua Liu, Ding-Guo Li, Xin Huang, Chun-Hua Zong, Qin-Fang Xu, Han-Ming Lu. Suppressive effects of 17&beta;-estradiol on hepatic fibrosis in CCl<sub>4</sub>-induced rat modelWorld Journal of Gastroenterology 2004; 10(9): 1315-1320 doi: 10.3748/wjg.v10.i9.1315
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Mary Jane Burton, James B. Brock, Stephen A. Geraci. Women with Chronic Hepatitis C Virus InfectionSouthern Medical Journal 2013; 106(7) doi: 10.1097/SMJ.0b013e31829b99f5
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He Tong, Li Wang, Kefan Zhang, Jing Shi, Yongshuai Wu, Yulong Bao, Changshan Wang. S100A6 Activates Kupffer Cells via the p-P38 and p-JNK Pathways to Induce Inflammation, Mononuclear/macrophage Infiltration Sterile Liver Injury in MiceInflammation 2023; 46(2) doi: 10.1007/s10753-022-01750-w
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Mohamed N. Abdelnabi, Ghada S. Hassan, Naglaa H. Shoukry. Role of the type 3 cytokines IL-17 and IL-22 in modulating metabolic dysfunction-associated steatotic liver diseaseFrontiers in Immunology 2024; 15 doi: 10.3389/fimmu.2024.1437046
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Max C.Y. Wong, Bernard Portmann, Roy Sherwood, Onni Niemela, Heidi Koivisto, Seppo Parkkila, Keith Trick, Mary R. L'Abbe, James Wilson, Philip R. Dash, Raj Srirajaskanthan, Victor R. Preedy, Helen Wiseman. The cytoprotective effect of α-tocopherol and daidzein against d-galactosamine–induced oxidative damage in the rat liverMetabolism 2007; 56(7) doi: 10.1016/j.metabol.2007.01.005
15
Meijun Yue, Yanlu Liu, Xiaoan Feng, Bo Cao, Xiaofei Fei, Guohui Li, Chunyu Li. Epimedii Folium flavonoids: A double-edged sword effect on the liver, a dual exploration of efficacy and toxicityJournal of Pharmaceutical Analysis 2025; 15(10) doi: 10.1016/j.jpha.2025.101269
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Devaraj Ezhilarasan. Critical role of estrogen in the progression of chronic liver diseasesHepatobiliary & Pancreatic Diseases International 2020; 19(5) doi: 10.1016/j.hbpd.2020.03.011
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Mark F. McCarty, Jorge Barroso-Aranda, Francisco Contreras. Genistein and phycocyanobilin may prevent hepatic fibrosis by suppressing proliferation and activation of hepatic stellate cellsMedical Hypotheses 2009; 72(3) doi: 10.1016/j.mehy.2008.07.045
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Eduardo Fernández-Martínez, Elvia Pérez-Soto, Carlos González-Hernández, Mario I. Ortiz, Víctor Pérez-Álvarez, Pablo Muriel, Mineko Shibayama. Immunomodulatory effects by oral contraceptives in normal and cholestatic female rats: Role of cytokinesInternational Immunopharmacology 2014; 21(1) doi: 10.1016/j.intimp.2014.03.022
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Alejandra Garate-Carrillo, Julisa Gonzalez, Guillermo Ceballos, Israel Ramirez-Sanchez, Francisco Villarreal. Sex related differences in the pathogenesis of organ fibrosisTranslational Research 2020; 222 doi: 10.1016/j.trsl.2020.03.008
20
Santiago Navarro-Ledesma. Frozen Shoulder as a Systemic Immunometabolic Disorder: The Roles of Estrogen, Thyroid Dysfunction, Endothelial Health, Lifestyle, and Clinical ImplicationsJournal of Clinical Medicine 2025; 14(20) doi: 10.3390/jcm14207315
21
Gracielle Alves-Amaral, Marcelo Pires-Oliveira, Ana Luiza Andrade-Lopes, Tiago Chiavegatti, Rosely Oliveira Godinho. Gender-related differences in circadian rhythm of rat plasma acetyl- and butyrylcholinesterase: Effects of sex hormone withdrawalChemico-Biological Interactions 2010; 186(1) doi: 10.1016/j.cbi.2010.04.002
22
Wanbao Yang, Jeffrey Guo, Shaodong Guo. Metabolic Syndrome2023;  doi: 10.1007/978-3-319-12125-3_28-3
23
Liwen Wang, Panpan Zhang, Xia Zhang, Wei Lin, Hanqi Tang, Jieqiong Li, Mu Wang, Xiaowei Liu, Yunyun Fei, Hua Chen, Linyi Peng, Li Zhang, Yamin Lai, Xuejun Zeng, Xuemei Li, Huadan Xue, Yan Zhao, Fengchun Zhang, Wen Zhang. Sex disparities in clinical characteristics and prognosis of immunoglobulin G4–related disease: a prospective study of 403 patientsRheumatology 2019; 58(5) doi: 10.1093/rheumatology/key397
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Ayako Suzuki, Einar S. Björnsson. Exploring the influence of sex on idiosyncratic DILI: impact on risk assessment Expert Opinion on Drug Metabolism & Toxicology 2026; 22(5) doi: 10.1080/17425255.2026.2671065
25
Zi Yi Chen, Mogellah John Panga, Xiangrui Zhang, Shuai Qiao, Shitian Chen, Clara Appiah, Ye Zhao. Estrogen alleviates liver fibrosis and restores metabolic homeostasis in ovariectomy-induced liver injury and carbon tetrachloride (CCl4) exposureEuropean Journal of Pharmacology 2024; 978 doi: 10.1016/j.ejphar.2024.176774
26
R Sato, C Maesawa, K Fujisawa, K Wada, K Oikawa, Y Takikawa, K Suzuki, H Oikawa, K Ishikawa, T Masuda. Prevention of critical telomere shortening by oestradiol in human normal hepatic cultured cells and carbon tetrachloride induced rat liver fibrosisGut 2004; 53(7) doi: 10.1136/gut.2003.027516
27
Zhuo Wang, Xinhao Li, Xiaoshan Liu, Yitao Yang, Yan Yan, Dedong Cui, Chenyang Meng, Maslah Idiris Ali, Jinming Zhang, Zeyu Yao, Yi Long, Rui Yang. Mechanistic insights into the anti-fibrotic effects of estrogen via the PI3K-Akt pathway in frozen shoulderThe Journal of Steroid Biochemistry and Molecular Biology 2025; 249 doi: 10.1016/j.jsbmb.2025.106701
28
Ebru Çetin, Murat Kanbur, Nazmi Çetin, Gökhan Eraslan, Ayhan Atasever. Hepatoprotective effect of ghrelin on carbon tetrachloride-induced acute liver injury in ratsRegulatory Peptides 2011; 171(1-3) doi: 10.1016/j.regpep.2011.05.010
29
James J DiNicolantonio, Mark F McCarty, Jorge Barroso-Aranda, Simon Assanga, Lidianys Maria Lewis Lujan, James H O'Keefe. A nutraceutical strategy for downregulating TGFβ signalling: prospects for prevention of fibrotic disorders, including post-COVID-19 pulmonary fibrosisOpen Heart 2021; 8(1) doi: 10.1136/openhrt-2021-001663
30
Zi Yi Chen, Mogellah John Panga, Xueting Wang, Shitian Chen, Ye Zhao. Sexual dimorphism in liver fibrotic metabolic dysfunction: Effects of testosterone and estrogen on CCl4-induced liver injury in ovariectomy and orchiectomy modelsThe Journal of Steroid Biochemistry and Molecular Biology 2026; 260 doi: 10.1016/j.jsbmb.2026.106995
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C. Castillo, V. Salazar, C. Ariznavarreta, E. Vara, J.A.F. Tresguerres. Effect of isoflavone administration on age-related hepatocyte changes in old ovariectomized femal Wistar ratsPhytomedicine 2006; 13(7) doi: 10.1016/j.phymed.2005.03.012
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Liana Codes, Tarik Asselah, Dominique Cazals-Hatem, Florence Tubach, Dominique Vidaud, Raymundo Paraná, Pierre Bedossa, Dominique Valla, Patrick Marcellin. Liver fibrosis in women with chronic hepatitis C: evidence for the negative role of the menopause and steatosis and the potential benefit of hormone replacement therapyGut 2007; 56(3) doi: 10.1136/gut.2006.101931
33
Ching-Chih Chang, Wen-Shin Lee, Chiao-Lin Chuang, I-Fang Hsin, Shao-Jung Hsu, Ting Chang, Hui-Chun Huang, Fa-Yauh Lee, Shou-Dong Lee. Effects of raloxifene on portal hypertension and hepatic encephalopathy in cirrhotic ratsEuropean Journal of Pharmacology 2017; 802 doi: 10.1016/j.ejphar.2017.02.039
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M Anbalagan, A Jagannadha Rao. Collagen IV-mediated signalling is involved in progenitor Leydig cell proliferationReproductive BioMedicine Online 2004; 9(4) doi: 10.1016/S1472-6483(10)61274-6
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Si Chenand, Jiekun Xuan, Lei Guo. microRNAs in Toxicology and Medicine2013;  doi: 10.1002/9781118695999.ch3
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Husna Yetti, Hisao Naito, Yuan Yuan, Xiaofang Jia, Yumi Hayashi, Hazuki Tamada, Kazuya Kitamori, Katsumi Ikeda, Yukio Yamori, Tamie Nakajima, Michael Bader. Bile acid detoxifying enzymes limit susceptibility to liver fibrosis in female SHRSP5/Dmcr rats fed with a high-fat-cholesterol dietPLOS ONE 2018; 13(2) doi: 10.1371/journal.pone.0192863
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Yue-Hong Huang, Mei-Na Shi, Wei-Da Zheng, Li-Juan Zhang, Zhi-Xin Chen, Xiao-Zhong Wang. Therapeutic effect of interleukin-10 on CCl<sub>4</sub>-induced hepatic fibrosis in ratsWorld Journal of Gastroenterology 2006; 12(9): 1386-1391 doi: 10.3748/wjg.v12.i9.1386
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Ayako Suzuki, Huiman Barnhart, Jiezhun Gu, Herbert L. Bonkovsky, Hans L. Tillmann, Robert J. Fontana, David E. Kleiner. Associations of gender and a proxy of female menopausal status with histological features of drug‐induced liver injuryLiver International 2017; 37(11) doi: 10.1111/liv.13380
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Jun-Wang Xu, Jun Gong, Xin-Ming Chang, Jin-Yan Luo, Lei Dong, Ai Jia, Gui-Ping Xu. Effects of estradiol on liver estrogen receptor-&alpha; and its mRNA expression in hepatic fibrosis in ratsWorld Journal of Gastroenterology 2004; 10(2): 250-254 doi: 10.3748/wjg.v10.i2.250
40
Kotaro Tokuda, Yoshiaki Yamanaka, Kenji Kosugi, Haruki Nishimura, Yasuaki Okada, Manabu Tsukamoto, Takafumi Tajima, Hitoshi Suzuki, Makoto Kawasaki, Soshi Uchida, Eiichiro Nakamura, Ke-Yong Wang, Akinori Sakai. Development of a novel knee contracture mouse model by immobilization using external fixationConnective Tissue Research 2022; 63(2) doi: 10.1080/03008207.2021.1892088
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Shanfei Ge, Jianping Xie, Fei Liu, Jinni He, Jinwen He. MicroRNA‐19b Reduces Hepatic Stellate Cell Proliferation by Targeting GRB2 in Hepatic Fibrosis Models In Vivo and In Vitro as Part of the Inhibitory Effect of EstradiolJournal of Cellular Biochemistry 2015; 116(11) doi: 10.1002/jcb.25116
42
Rong Wang, Xiao-Yan Yu, Zhu-Ying Guo, Yu-Jie Wang, Yan Wu, Yong-Fang Yuan. Inhibitory effects of salvianolic acid B on CCl4-induced hepatic fibrosis through regulating NF-κB/IκBα signalingJournal of Ethnopharmacology 2012; 144(3) doi: 10.1016/j.jep.2012.09.048
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Kusum K. Kharbanda, Shilpa Chokshi, Irina Tikhanovich, Steven A. Weinman, Moses New-Aaron, Murali Ganesan, Natalia A. Osna. A Pathogenic Role of Non-Parenchymal Liver Cells in Alcohol-Associated Liver Disease of Infectious and Non-Infectious OriginBiology 2023; 12(2) doi: 10.3390/biology12020255
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Ziheng Yang, Jie Zhang, Yan Wang, Jing Lu, Quan Sun. Caveolin-1 Deficiency Protects Mice Against Carbon Tetrachloride-Induced Acute Liver Injury Through Regulating Polarization of Hepatic MacrophagesFrontiers in Immunology 2021; 12 doi: 10.3389/fimmu.2021.713808
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Yaqin Zhang, Linping Wu, Yang Wang, Mingcao Zhang, Limin Li, Dihan Zhu, Xihan Li, Hongwei Gu, Chen-Yu Zhang, Ke Zen. Protective Role of Estrogen-induced miRNA-29 Expression in Carbon Tetrachloride-induced Mouse Liver InjuryJournal of Biological Chemistry 2012; 287(18) doi: 10.1074/jbc.M111.314922
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Cheng Jin, Pei-Jian Zhang, Chuan-Qing Bao, Yuan-Long Gu, Bing-Hua Xu, Cheng-Wan Li, Jian-Ping Li, Ping Bo, Xin-Nong Liu. Protective Effects ofAtractylodes macrocephalaPolysaccharide on Liver Ischemia–Reperfusion Injury and Its Possible Mechanism in RatsThe American Journal of Chinese Medicine 2011; 39(03) doi: 10.1142/S0192415X11008981
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Anouk Oldenburger, Gerald Birk, Marco Schlepütz, Andre Broermann, Birgit Stierstorfer, Steven S. Pullen, Jörg F. Rippmann. Modulation of vascular contraction via soluble guanylate cyclase signaling in a novel ex vivo method using rat precision‐cut liver slicesPharmacology Research & Perspectives 2021; 9(3) doi: 10.1002/prp2.768
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CARLOS A.P. CABRAL, FRANCISCO J.B. SAMPAIO, LUIZ E.M. CARDOSO. Analysis of the Modifications in the Composition of Bladder Glycosaminoglycan and Collagen as a Consequence of Changes in Sex Hormones Associated With Puberty or Oophorectomy in Female RatsJournal of Urology 2003; 170(6) doi: 10.1097/01.ju.0000088776.17126.93
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Shotaro NISHIMURA, Akifumi TESHIMA, Vishwajit Sur CHOWDHURY, Shoji TABATA. Changes in collagen fiber content and hepatic stellate cell distribution in the liver of chick embryos and growing chickensAnimal Science Journal 2012; 83(6) doi: 10.1111/j.1740-0929.2011.00986.x
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Fabio Marra, Sara Galastri, Sara Aleffi, Massimo Pinzani. Signaling Pathways in Liver Diseases2010;  doi: 10.1007/978-3-642-00150-5_3
51
Ya-jun Zhou, Dong-mei Yin, Hong-shan Chen, Jian-hua Shi, Bao-xi Sha, Xing Wang. Inhibitory effects of idoxifene on hepatic fibrosis in ratsActa Pharmacologica Sinica 2005; 26(5) doi: 10.1111/j.1745-7254.2005.00082.x
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Philipp Königshofer, Ksenia Brusilovskaya, Oleksandr Petrenko, Benedikt Silvester Hofer, Philipp Schwabl, Michael Trauner, Thomas Reiberger. Nuclear receptors in liver fibrosisBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2021; 1867(12) doi: 10.1016/j.bbadis.2021.166235
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Yukihiro Yokoyama, Yuji Nimura, Masato Nagino, Kirby I. Bland, Irshad H. Chaudry. Current Understanding of Gender Dimorphism in Hepatic Pathophysiology1Journal of Surgical Research 2005; 128(1) doi: 10.1016/j.jss.2005.04.017
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Diana M. Lindquist, Elizabeth M. Fugate, Jiang Wang, Akanksha Sharma, Chandrashekhar R. Gandhi, Jonathan R. Dillman. MRI Measures of Murine Liver FibrosisJournal of Magnetic Resonance Imaging 2021; 54(3) doi: 10.1002/jmri.27601
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Shrirang Jamadagni, Pallavi Jamadagni, Binita Angom, Dhirendranath Mondal, Sachchidanand Upadhyay, Sudesh Gaidhani, Jayram Hazra. Tissue distribution of mercury and copper after Aarogyavardhini Vati treatment in rat model of CCl4 induced chronic hepatotoxicityJournal of Ayurveda and Integrative Medicine 2020; 11(4) doi: 10.1016/j.jaim.2019.09.005
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Michael Trauner, Emina Halilbasic. Nuclear Receptors as New Perspective for the Management of Liver DiseasesGastroenterology 2011; 140(4) doi: 10.1053/j.gastro.2011.02.044
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Bin Zhang, Cheng‐Gang Zhang, Lin‐Hua Ji, Gang Zhao, Zhi‐Yong Wu. Estrogen receptor β selective agonist ameliorates liver cirrhosis in rats by inhibiting the activation and proliferation of hepatic stellate cellsJournal of Gastroenterology and Hepatology 2018; 33(3) doi: 10.1111/jgh.13976
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Daisuke Tokuhara. Role of the Gut Microbiota in Regulating Non-alcoholic Fatty Liver Disease in Children and AdolescentsFrontiers in Nutrition 2021; 8 doi: 10.3389/fnut.2021.700058
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Ragaa H. M. Salama, Safaa S. Ali, Tarek Hamdy M. Salama, Mohamed Abu Almged, Tasneem A. Alsanory, Aya A. Alsanory, Hesham Aboutaleb, Ghada M. Ezzat. Dietary Effects of Nanopowder Eggshells on Mineral Contents, Bone Turnover Biomarkers, and Regulators of Bone Resorption in Healthy Rats and Ovariectomy-Induced Osteoporosis Rat ModelApplied Biochemistry and Biotechnology 2023; 195(8) doi: 10.1007/s12010-022-04038-9
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Sumaira Sahreen, Muhammad Rashid Khan, Rahmat Ali Khan. Evaluation of Rumex hastatus leaves against hepatic fibrosis: a rat modelBMC Complementary and Alternative Medicine 2017; 17(1) doi: 10.1186/s12906-017-1943-5
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Manish Bishnolia, Poonam Yadav, Sumeet Kumar Singh, Nirmal Manhar, Sonu Rajput, Amit Khurana, Jasvinder Singh Bhatti, Umashanker Navik. Methyl donor ameliorates CCl4-induced liver fibrosis by inhibiting inflammation, and fibrosis through the downregulation of EGFR and DNMT-1 expressionFood and Chemical Toxicology 2025; 196 doi: 10.1016/j.fct.2024.115230
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Matteo Ricchi, Marco Bertolotti, Claudia Anzivino, Lucia Carulli, Irene Canedi, Maria Luisa Bormioli, Roberta Tiozzo, Maria Antonietta Croce, Amedeo Lonardo, Nicola Carulli, Paola Loria. 17β‐estradiol prevents cytotoxicity from hydrophobic bile acids in HepG2 and WRL‐68 cell culturesJournal of Gastroenterology and Hepatology 2006; 21(5) doi: 10.1111/j.1440-1746.2006.04144.x
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Tanvi Potluri, Tianming You, Ping Yin, John Coon, Jonah J. Stulberg, Yang Dai, David J. Escobar, Richard L. Lieber, Hong Zhao, Serdar E. Bulun. Estrogen receptor-α ablation reverses muscle fibrosis and inguinal herniasJournal of Clinical Investigation 2025; 135(6) doi: 10.1172/JCI179137
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Lifeng Ning, Xiaofang Gong, Peng Li, Xiaofeng Chen, Huiping Wang, Juan Xu. Measurement and correlation of the solubility of estradiol and estradiol-urea co-crystal in fourteen pure solvents at temperatures from 273.15 K to 318.15 KJournal of Molecular Liquids 2020; 304 doi: 10.1016/j.molliq.2020.112599
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Mark F. McCarty. Complementary and Alternative Therapies and the Aging Population2009;  doi: 10.1016/B978-0-12-374228-5.00024-X
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Faried Abdel-Kader El-Sayed Hemieda. Influence of gender on tamoxifen-induced biochemical changes in serum of ratsMolecular and Cellular Biochemistry 2007; 301(1-2) doi: 10.1007/s11010-006-9405-2
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Neriman Colakoglu, Ilter Kus, Aysel Kukner, Hidir Pekmez, Enver Ozan, Mustafa Sarsilmaz. Protective Effects of CAPE on Liver Injury Induced by CCL4: An Electron Microscopy StudyUltrastructural Pathology 2011; 35(1) doi: 10.3109/01913123.2010.527036
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A. Hassouna, E. Obaia, S. Marzouk, M. Rateb, Mohamed Haidara. The role of sex hormones in induced-systemic inflammation in female albino ratsActa Physiologica Hungarica 2014; 101(1) doi: 10.1556/APhysiol.101.2014.1.12
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Junyan Yan, Huarong Huang, Zuping Liu, Jiayuan Shen, Jian Ni, Jiwei Han, Renjun Wang, Derong Lin, Baowei Hu, Lifang Jin. Hedgehog signaling pathway regulates hexavalent chromium-induced liver fibrosis by activation of hepatic stellate cellsToxicology Letters 2020; 320 doi: 10.1016/j.toxlet.2019.11.017
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Kotaro Tokuda, Yoshiaki Yamanaka, Yosuke Mano, Manabu Tsukamoto, Takafumi Tajima, Hitoshi Suzuki, Makoto Kawasaki, Soshi Uchida, Eiichiro Nakamura, Ke-Yong Wang, Akinori Sakai. Effect of metformin treatment and its time of administration on joint capsular fibrosis induced by mouse knee immobilizationScientific Reports 2021; 11(1) doi: 10.1038/s41598-021-97445-7
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Qiwang Ma, Jianjun Zhao, Wei Cao, Jiali Liu, Sheng Cui. Estradiol decreases taurine level by reducing cysteine sulfinic acid decarboxylase via the estrogen receptor-α in female mice liverAmerican Journal of Physiology-Gastrointestinal and Liver Physiology 2015; 308(4) doi: 10.1152/ajpgi.00107.2014
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Samim Ali Mondal, Roshini Sathiaseelan, Shivani N. Mann, Maria Kamal, Wenyi Luo, Tatiana D. Saccon, José V. V. Isola, Frederick F. Peelor, Tiangang Li, Willard M. Freeman, Benjamin F. Miller, Michael B. Stout. 17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male miceAmerican Journal of Physiology-Endocrinology and Metabolism 2023; 324(2) doi: 10.1152/ajpendo.00256.2022
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Kow-Aung Chang, I-Chun Lin, Jiunn-Ming Sheen, Yu-Chieh Chen, Chih-Cheng Chen, You-Lin Tain, Chih-Sung Hsieh, Li-Tung Huang. Sex Differences of Oxidative Stress to Cholestatic Liver and Kidney Injury in Young RatsPediatrics & Neonatology 2013; 54(2) doi: 10.1016/j.pedneo.2012.11.008
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Jie-Wen Zhang, Nan Zhang, Yi Lyu, Xu-Feng Zhang. Influence of Sex in the Development of Liver DiseasesSeminars in Liver Disease 2025; 45(01) doi: 10.1055/a-2516-0261
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Mabrouk A. Abo‐Zaid, Emad S. Shaheen, Ahmed H. Ismail. Immunomodulatory effect of curcumin on hepatic cirrhosis in experimental ratsJournal of Food Biochemistry 2020; 44(6) doi: 10.1111/jfbc.13219
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Thikryat Neamatallah, Ashraf B. Abdel-Naim, Basma G. Eid, Atif Hasan. 2-Methoxyestradiol attenuates liver fibrosis in mice: implications for M2 macrophagesNaunyn-Schmiedeberg's Archives of Pharmacology 2019; 392(3) doi: 10.1007/s00210-018-1577-2
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Bin Zhang, Zhi-Yong Wu. Estrogen derivativesEuropean Journal of Gastroenterology & Hepatology 2013; 25(3) doi: 10.1097/MEG.0b013e32835ab5dc
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Chanbin Lee, Jieun Kim, Youngmi Jung. Potential Therapeutic Application of Estrogen in Gender Disparity of Nonalcoholic Fatty Liver Disease/Nonalcoholic SteatohepatitisCells 2019; 8(10) doi: 10.3390/cells8101259
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E. Fernández-Martínez. Liver Pathophysiology2017;  doi: 10.1016/B978-0-12-804274-8.00018-7
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Scott L. Friedman. Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the LiverPhysiological Reviews 2008; 88(1) doi: 10.1152/physrev.00013.2007
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Sukriti Baweja, Ashmit Mittal, Swati Thangariyal, P. Debishree Subudhi, Shivani Gautam, Rashmi Kaul. Unveiling the effect of estrogen receptors in alcoholic liver disease: A novel outlookLiver Research 2023; 7(4) doi: 10.1016/j.livres.2023.10.002
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Md. Mizanur Rahman, Nusaira Beenta Shahab, Pintu Miah, Md Mahamudur Rahaman, Arafat Ulla Kabir, Nusrat Subhan, Ahad Ali Khan, Mirola Afroze, Mala Khan, K. Shahin Ahmed, Hemayet Hossain, Md. Areeful Haque, Md Ashraful Alam. Polyphenol-rich leaf of Aphanamixis polystachya averts liver inflammation, fibrogenesis and oxidative stress in ovariectomized Long-Evans ratsBiomedicine & Pharmacotherapy 2021; 138 doi: 10.1016/j.biopha.2021.111530
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Renye Que, Yanting Shen, Jianlin Ren, Zhihui Tao, Xiaoyan Zhu, Yong Li. Estrogen receptor‑β‑dependent effects of saikosaponin‑d on the suppression of oxidative stress‑induced rat hepatic stellate cell activationInternational Journal of Molecular Medicine 2017;  doi: 10.3892/ijmm.2017.3349
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Maria Lina Tornesello, Anna Lucia Tornesello, Noemy Starita, Andrea Cerasuolo, Francesco Izzo, Luigi Buonaguro, Franco Maria Buonaguro. Telomerase: a good target in hepatocellular carcinoma? An overview of relevant preclinical dataExpert Opinion on Therapeutic Targets 2022; 26(9) doi: 10.1080/14728222.2022.2147062
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Wanbao Yang, Jeffrey Guo, Shaodong Guo. Metabolic Syndrome2023;  doi: 10.1007/978-3-031-40116-9_28
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