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Oct 28, 2024 (publication date) through Feb 23, 2026
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World Journal of Gastroenterology
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1007-9327
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| Singh AK, Durairajan SSK, Iyaswamy A, Williams LL. Elucidating the role of gut microbiota dysbiosis in hyperuricemia and gout: Insights and therapeutic strategies. World J Gastroenterol 2024; 30(40): 4404-4410 [PMID: 39494101 DOI: 10.3748/wjg.v30.i40.4404] |
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| ©2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA | |
| For: | Singh AK, Durairajan SSK, Iyaswamy A, Williams LL. Elucidating the role of gut microbiota dysbiosis in hyperuricemia and gout: Insights and therapeutic strategies. World J Gastroenterol 2024; 30(40): 4404-4410 [PMID: 39494101 DOI: 10.3748/wjg.v30.i40.4404] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v30/i40/4404.htm |
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Ying Yang, Yu Wang, Jinjian Huang, Yi Xu, Xiaoyang Yin, Zhijian Lin, Bing Zhang. Influence of Gut Microbiota-Derived Butyrate on Intestinal Uric Acid Excretion and Hyperuricemia Regulation by Cichorium intybus L.. International Journal of Molecular Sciences 2025; 26(13): 6413 doi: 10.3390/ijms26136413
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Tingli Qu, Nan Zhang, Junjie Cai, Chen Li, Yue Zhang, Xinxue Xu, Shuai Zhang, Wangwei Lv, Taigang Liang. Integrated bioinformatics and multi-omics reveal Astragalus extract’s gut-kidney axis mechanism in hyperuricemic nephropathy via purine metabolism. Phytomedicine 2025; 146: 157121 doi: 10.1016/j.phymed.2025.157121
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Yanling Che, Lina Zhao, Haoxuan Xu, Yijiao Cai, Ziqi Wu, Lili Zhong. Serum uric acid to high‑density lipoprotein cholesterol ratio as a novel predictor of diabetic nephropathy: a cross‑sectional analysis of NHANES 2011–2018. Clinical and Experimental Medicine 2025; 25(1) doi: 10.1007/s10238-025-01893-8
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Wei-Ting Tseng, Xiang-Ru Kong, Yu-Tsung Han, Wen-Yang Lin, Deyi Yin, Lei Du, Jingli Xie, Tien-Hung Chang. Lacticaseibacillus paracasei LT12—A Probiotic Strain That Reduces Hyperuricemia via Inhibiting XO Activity and Regulating Renal Uric Acid Transportation Protein. Fermentation 2025; 11(2): 96 doi: 10.3390/fermentation11020096
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Linglan Suo, Yangling Xiang, Guiqiu Zhou, Xin Ma, Dayong Ren, Yue Leng. Heat-inactivated Akkermansia muciniphila AKK PROBIO attenuates hyperuricemia via integrated modulation of uric acid metabolism, TLR4/NF-κB/NLRP3 pathway, and gut microbiota. Biochemical and Biophysical Research Communications 2026; 797: 153174 doi: 10.1016/j.bbrc.2025.153174
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Hongyu Zhang, Da Wang, Chaoran Li, Fengchen Xu, Xiangheng Cao, Bingkun Bao, Mengge Zhao, Xuebo Liu. Comprehensive Evaluation of the Antihyperuricemic Effect of Red Kidney Bean Anthocyanins and Molecular Screening of the Lead Candidate. Journal of Agricultural and Food Chemistry 2026; 74(1): 968 doi: 10.1021/acs.jafc.5c14579
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Wujin Chen, Tingting Tian, Jingru Zhou, Dan Yang, Meiting Liang, Yi He, Shanshan Yang, Dilinuer Aikepa, Yuping Sun. Safety Evaluation of Human-Derived Uric Acid Degrading Lacticaseibacillus paracasei M2a and Its Impact on Gut Microbiota. Probiotics and Antimicrobial Proteins 2025; doi: 10.1007/s12602-025-10562-x
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Supriti Patnaik, Siva Sundara Kumar Durairajan, Abhay Kumar Singh, Senthilkumar Krishnamoorthi, Ashok Iyaswamy, Shiva Prasad Mandavi, Rajesh Jeewon, Leonard L Williams. Role of <i>Candida</i> species in pathogenesis, immune regulation, and prognostic tools for managing ulcerative colitis and Crohn's disease. World Journal of Gastroenterology 2024; 30(48): 5212-5220 doi: 10.3748/wjg.v30.i48.5212
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Jia-Wei Tang, Alfred Chin Yen Tay, Liang Wang. Interpretive prediction of hyperuricemia and gout patients via machine learning analysis of human gut microbiome. BMC Microbiology 2025; 25(1) doi: 10.1186/s12866-025-04125-x
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Hua-Jun Zhang, Shui-Quan Jin, Ding-Jun Cai, Zhi-Peng He. Herbal medicine beyond probiotics: Yiyi Fuzi Baijiang powder and the holistic regulation of gut microbiota in ulcerative colitis. World Journal of Gastroenterology 2026; 32(1): 115543 doi: 10.3748/wjg.v32.i1.115543
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Guizhen Zhu, Yuan Luo, Xiangyi Zheng, Zhusong Mei, Qiao Ye, Jie Peng, Fengsen Duan, Yueying Cui, Peiyu An, Yangqian Song, Hongxia Li, Haitao Zhang, Guangyun Wang. Multi-Omics Mechanism of Chronic Gout Arthritis and Discovery of the Thyroid Hormone–AMPK–Taurine Metabolic Axis. Cells 2025; 15(1): 41 doi: 10.3390/cells15010041
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Qisijing Liu, Wentao Gu, Juan Ma, Jin Wang, Miao Yu, Min Xu, Shuo Wang. A Pilot Randomized Controlled Trial and Multi-Omics Analysis of Electrolysed Alkaline Water: Impacts on Gut Microbiota and Metabolic Signatures in Hyperuricemia. Nutrients 2025; 18(1): 107 doi: 10.3390/nu18010107
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Yan Xiao, Ting Zhang, Qianglong Chen, Yiqian Zhang, Bingyan Chen, Meiling Wang, Yingjie Zhang, Mingqing Huang, Youxin Su, Jiemei Guo. Multi-omics analysis reveals the mechanism of verbenalin in treating gout via modulating purine metabolism, gut microbiota, and inflammatory pathways. Frontiers in Immunology 2026; 17 doi: 10.3389/fimmu.2026.1761558
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| 21 |
学志 余. Research Progress on the Role of Natural Active Ingredients and Traditional Chinese Medicine Compound in Improving Hyperuricemia through Gut-Mediated Pathways. Advances in Clinical Medicine 2026; 16(01): 2480 doi: 10.12677/acm.2026.161310
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| 22 |
Junyu Yang, Jiali Chen, Zhenmin Liu, Yezhi Qu, Xiqing Yue, Bo Yuan, Mohan Li. The Role of the Intestinal Microbiome in the Pathogenesis and Treatment of Hyperuricemia: A Review. Food Science & Nutrition 2025; 13(10) doi: 10.1002/fsn3.70982
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Danping Zhao, Yuannan Wang, Tingting He, Yingna Chen, Yu Bai, Yuchun Huang, Kaiyue Ding, Junnan Ma, Lin Zhang. Puerariae lobatae Radix aqueous extract ameliorates asymptomatic hyperuricemia in a potassium oxonate-induced rat model by dual modulation of uric acid production and excretion. Frontiers in Nutrition 2025; 12 doi: 10.3389/fnut.2025.1685674
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Yujing Cui, Haoyue Guan, Samuel Kumi Okyere, Zixuan Hua, Youtian Deng, Huidan Deng, Zhihua Ren, Junliang Deng. Microbial Guardians or Foes? Metagenomics Reveal Association of Gut Microbiota in Intestinal Toxicity Caused by DON in Mice. International Journal of Molecular Sciences 2025; 26(4): 1712 doi: 10.3390/ijms26041712
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Yueying Cui, Peiyu An, Feng Li, Fengsen Duan, Zusong Mei, Qiao Ye, Guangyun Wang, Haitao Zhang, Yuan Luo. Strategies to reduce uric acid through gut microbiota intervention. Frontiers in Microbiology 2025; 16 doi: 10.3389/fmicb.2025.1654152
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Yang Zhang, Fanyi He, Xuezhi Yu, Tiantian Li, Li Zhou, Baochun Shen. Hyperuricemia-induced kidney injury: a narrative review of mechanisms and therapeutic advances. BMC Nephrology 2025; 26(1) doi: 10.1186/s12882-025-04414-7
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