| For: | Peng T, Sun F, Yang JC, Cai MH, Huai MX, Pan JX, Zhang FY, Xu LM. Novel lactylation-related signature to predict prognosis for pancreatic adenocarcinoma. World J Gastroenterol 2024; 30(19): 2575-2602 [PMID: 38817665 DOI: 10.3748/wjg.v30.i19.2575] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v30/i19/2575.htm |
| Number | Citing Articles |
| 1 |
Qinwen Ba, Xiong Wang, Yanjun Lu. Establishment of a prognostic model for pancreatic cancer based on mitochondrial metabolism related genes. Discover Oncology 2024; 15(1) doi: 10.1007/s12672-024-01255-y
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| 2 |
Xiaolei Ma, Mengxing Cheng, Yanxin Jia, Kun Zhang, Haocheng Zhang, Di Feng, Wenxiao Xu, Guofen Qiao. Demethylzeylasteral suppresses the expression of MESP1 by reducing H3K18la level to inhibit the malignant behaviors of pancreatic cancer. Cell Death Discovery 2025; 11(1) doi: 10.1038/s41420-025-02603-9
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| 3 |
Lin‐Ting Zhang, Xin‐Yi Wu, Hai‐Yu Zhang, En‐Min Li, Li‐Yan Xu, Lin Long. Exploring solute carriers as biomarkers and therapeutic targets in esophageal squamous cell carcinoma. International Journal of Cancer 2026; 158(1): 19 doi: 10.1002/ijc.70080
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| 4 |
Pu Shen, Meng Yang. Research advances of lactylation modification in breast cancer. Discover Oncology 2025; 16(1) doi: 10.1007/s12672-025-03663-0
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| 5 |
Claudiu Natanael Roznovan, Luminița Gabriela Măruțescu, Gratiela Gradisteanu Pircalabioru. Immuno-Oncology at the Crossroads: Confronting Challenges in the Quest for Effective Cancer Therapies. International Journal of Molecular Sciences 2025; 26(13): 6177 doi: 10.3390/ijms26136177
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| 6 |
Qiyu Chi, Feihong Liang, Yaxin Zhang, Changgan Chen, Xuling Chen, Yu Pan, Shangeng Weng. Integrated transcriptome and single-cell RNA sequencing analysis revealed the prognostic significance of GBP4 in pancreatic adenocarcinoma. Translational Oncology 2025; 61: 102532 doi: 10.1016/j.tranon.2025.102532
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| 7 |
Linna Chen, Meng Xia, Weijia Wen, Li Yuan, Yan Jia, Xueyuan Zhao, Haolin Fan, Songlin Liu, Tianyu Liu, Pan Liu, Hongye Jiang, Wei Wang, Yuandong Liao, Chunyu Zhang, Shuzhong Yao. Identification and Validation of a Novel Lactylation-related Gene Signature to Predict the Prognosis of Endometrial Cancer. Discover Oncology 2025; 16(1) doi: 10.1007/s12672-025-02663-4
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| 8 |
Xu Zhang, Changming Liang, Chengwei Wu, Senlin Wan, Lishuai Xu, Song Wang, Jiawei Wang, Xiaoxu Huang, Li Xu. A rising star involved in tumour immunity: Lactylation. Journal of Cellular and Molecular Medicine 2024; 28(20) doi: 10.1111/jcmm.70146
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| 9 |
Jiewen Wang, Mingjing Peng, Linda Oyang, Mengzhou Shen, Shizhen Li, Xianjie Jiang, Zongyao Ren, Qiu Peng, Xuemeng Xu, Shiming Tan, Longzheng Xia, Wenjuan Yang, Haofan Li, Nayiyuan Wu, Yanyan Tang, Jinguan Lin, Qianjin Liao, Yaqian Han, Yujuan Zhou. Mechanism and application of lactylation in cancers. Cell & Bioscience 2025; 15(1) doi: 10.1186/s13578-025-01415-9
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| 10 |
Zhenhao Xu, Yisha Huang, Xiuling Yu, Jiajia Xuan, Wanting Liu. Multi-Omics Integration of Lactylation- and PANoptosis-Based Signatures in Lung Adenocarcinoma: Prognostic Stratification and Immune Response. International Journal of Molecular Sciences 2025; 26(13): 5999 doi: 10.3390/ijms26135999
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| 11 |
Xiaomei Wang, Jiaqing Chen, Bing Wang, Yanping Li, Xinyue Zhou, Yingqiu Song, Chenggui Miao, Yurong Huang. Impact of lactylation on the pathogenesis of cancer and its clinical application potential (Review). Molecular Medicine Reports 2025; 32(6): 1 doi: 10.3892/mmr.2025.13702
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| 12 |
Peiting Wu, Juan Zhang, Zhengwu Jiang, Xueru Liu, Ni Jiang, Juan Zou, Xun Chen, Daichao Wu, Yukun Li. Lactate-lactylation in tumor angiogenesis and progression: mechanisms, biomarker potential, and therapeutic implications. Biomarker Research 2026; 14(1) doi: 10.1186/s40364-026-00898-z
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| 13 |
Xiangnan Feng, Dayong Li, Pingyu Wang, Xinyu Li, Guangyao Li. Lactylation in Cancer: Unlocking the Key to Drug Resistance and Therapeutic Breakthroughs. Oncology Research 2025; 33(11): 3327 doi: 10.32604/or.2025.067343
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| 14 |
Zhenhao Wang, Hanlin Du, Zhuming Yang, Yuanyuan Zhang, Zhenya Hong. The role of lactic acid metabolism in anti-tumor immunity. Critical Reviews in Oncology/Hematology 2026; 221: 105183 doi: 10.1016/j.critrevonc.2026.105183
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| 15 |
Juli Tang, Lingyan Yuan, Yong-Li Han. Metabolic-immune crosstalk in myocardial infarction: RLF and SMCHD1 identified as causal therapeutic targets via integrated lactylation-MR analysis. Frontiers in Cell and Developmental Biology 2025; 13 doi: 10.3389/fcell.2025.1653551
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| 16 |
Yangyang Xiao, Zhiru Zhong, Chunli Yang, Zhiying Lin. Multivariate Cox regression analysis of prognostic genes and therapeutic mechanisms of gastric cancer. Discover Oncology 2025; 16(1) doi: 10.1007/s12672-025-01907-7
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| 17 |
Muhammad Muddasar Saeed, Xinying Ma, Xinyu Fu, Ikram Ullah, Tanveer Ali, Changchuan Bai, Ying Liu, Chengyong Dong, Xiaonan Cui. RACGAP1 and MKI67 are potential prognostic biomarker in hepatocellular carcinoma caused by HBV/HCV via lactylation. Frontiers in Oncology 2025; 15 doi: 10.3389/fonc.2025.1537084
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| 18 |
Xu Yan, Guangming Zhang, Huayuan Wei, Lin Yang, Xijuan Jiang. Lysine lactylation: Regulatory mechanisms, role in health and disease, and its therapeutic potential. Drug Discovery Today 2025; 30(8): 104420 doi: 10.1016/j.drudis.2025.104420
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| 19 |
Zhuangwei Lv, Ruohao Yang, Lulu Liu, Xiaoyu Shi, Ruihan Wang, Jinhua Wu, Junna Jiao. Lactylation as a cross-regulatory node in tumor metabolism and epigenetics: insights and therapeutic implications. Frontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1675480
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| 20 |
Yujie Fan, Zhangda Chen, Jiaxin Li, Lidan Ding. Effects of lactylation on the hallmarks of cancer (Review). Oncology Letters 2025; 30(5): 1 doi: 10.3892/ol.2025.15238
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| 21 |
Luojin Wu, Qing Sun, Atsushi Kitani, Xiaorong Zhou, Liming Mao, Mengmeng Sang. Constructing a Pan-Cancer Prognostic Model via Machine Learning Based on Immunogenic Cell Death Genes and Identifying NT5E as a Biomarker in Head and Neck Cancer. Current Issues in Molecular Biology 2025; 47(10): 812 doi: 10.3390/cimb47100812
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| 22 |
Gang Wang, Xiaosu Zou, Qicong Chen, Wenqian Nong, Weiwei Miao, Honglin Luo, Shenhong Qu. The relationship and clinical significance of lactylation modification in digestive system tumors. Cancer Cell International 2024; 24(1) doi: 10.1186/s12935-024-03429-8
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| 23 |
Ting Wen, Lihua Yang, Shuang Cai, Yunxia Liu, Jianan Fan, Peng Wu, Beibei Gao, Xiaoge Xie, Hong Sun, Sida Qin, Qiao Yi Chen. SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis. Advanced Science 2026; doi: 10.1002/advs.202522996
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| 24 |
Peipei Wang, Kexin Lin, Degao Huang, Zihan Jiang, Linchuan Liao, Xia Wang. The regulatory role of protein lactylation in various diseases: Special focus on the regulatory role of non-histone lactylation. Gene 2025; 963: 149595 doi: 10.1016/j.gene.2025.149595
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| 25 |
Jie Chen, Ziyue Huang, Ya Chen, Hao Tian, Peiwei Chai, Yongning Shen, Yiran Yao, Shiqiong Xu, Shengfang Ge, Renbing Jia. Lactate and lactylation in cancer. Signal Transduction and Targeted Therapy 2025; 10(1) doi: 10.1038/s41392-024-02082-x
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| 26 |
Lianghe Yu, Yan Shi, Zhenyu Zhi, Shuang Li, Wenlong Yu, Yongjie Zhang, Minghua Ren. Establishment of a Lactylation‐Related Gene Signature for Hepatocellular Carcinoma Applying Bulk and Single‐Cell RNA Sequencing Analysis. International Journal of Genomics 2025; 2025(1) doi: 10.1155/ijog/3547543
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| 27 |
Dandan Wang, Hao Rong, Ke Ma, Jun Peng. Lactylation in tumor: mechanisms and therapeutic potentials. Frontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1609596
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| 28 |
Mokhtar Rejili. Metabolic-epigenetic rewiring in cancer: The role of lactylation in tumor progression, immune evasion, and therapy resistance. Pathology - Research and Practice 2025; 275: 156244 doi: 10.1016/j.prp.2025.156244
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| 29 |
Wuyang Zhang, Shuai Ming, Peng Cheng, Dan Shi, Jingyu Li, Bin Wang, Yu Fang, Mengru Li, Wei Cao, Min Wang, Zaibao Wang, Jiawei Xiao, Wei Wei. Lactylation-related multigene signature in multiple myeloma: integrated prognostic stratification, immune landscape profiling, and therapeutic guidance. Immunologic Research 2025; 73(1) doi: 10.1007/s12026-025-09718-2
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| 30 |
Qiaoling Tong, Chunsheng Huang, Qizhen Tong, Zhiyu Zhang. Histone lactylation: A new frontier in laryngeal cancer research (Review). Oncology Letters 2025; 30(3): 1 doi: 10.3892/ol.2025.15167
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| 31 |
Yuxiang Luo, Ning Zhang, Jiarong Ye, Zuao Wang, Xinchi Zhou, Jipeng Liu, Jing Cai, Chen Li, Leifeng Chen. Unveiling lactylation modification: A new hope for cancer treatment. Biomedicine & Pharmacotherapy 2025; 184: 117934 doi: 10.1016/j.biopha.2025.117934
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| 32 |
Jinfeng Ye, Yunliang Lu, Wansu Huang, Shan Huang, Zhe Zhang, Xiaoying Zhou, Xue Xiao, Tingting Huang. The lactylation-immunosuppression network in cancer: driving a metabolic-epigenetic axis. Frontiers in Immunology 2026; 17 doi: 10.3389/fimmu.2026.1752934
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| 33 |
Qinglong Du, CuiYu Meng, Wenchao Zhang, Li Huang, Chunlei Xue, Songyun Zhao. Establishing a Prognostic Model Correlates to Inflammatory Response Pathways for Prostate Cancer via Multiomic Analysis of Lactylation‐Related Genes. International Journal of Genomics 2025; 2025(1) doi: 10.1155/ijog/6681711
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| 34 |
Xuebo Wang, Xusheng Zhang, Shicai Liang, Jialong Wang, Yannan Xie, Jiawei Wang, Bendong Chen. Integrative Analysis of eQTL Genes Reveals Key Biomarkers and Mechanisms for Early Diagnosis of Pancreatic Ductal Adenocarcinoma. Cancer Informatics 2025; 24 doi: 10.1177/11769351251400465
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| 35 |
Chenyuan Dai, Lihua Wang. Glycolysis enzymes and cellular lactylation in tumour. Clinical and Translational Medicine 2026; 16(2) doi: 10.1002/ctm2.70549
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| 36 |
Jun Wei, Qian Ding, Hongjun Wang, Yang Liu. Lactylation in digestive system tumors: from mechanisms to therapeutic target. Frontiers in Oncology 2025; 15 doi: 10.3389/fonc.2025.1607249
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| 37 |
Boxiang Zhang, Yuting Yan, Shuyang Chen, Yongqing Sun, Lun Li, Jingtong Su, Guangyu Li. Lactate beyond waste: lactylation as a therapeutic target in glioma. Biochemical Pharmacology 2026; 248: 117838 doi: 10.1016/j.bcp.2026.117838
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| 38 |
Dong Xu, Qiuyang Chen, Liang Wang, Liangliang Li, Kangwen Cheng, Xinchun Liu, Kai Lin. Lactylation profiling reveals novel biomarkers and immune interactions in pancreatic cancer. Translational Oncology 2026; 66: 102710 doi: 10.1016/j.tranon.2026.102710
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| 39 |
Chen-Hui Zhang, An-Qi Huang, Cang-Chang Shi, Zhi-Jia Jiang, Hao Yao, Jin-Jin Sun. Hypoxia- and lactate metabolism-associated prognostic and therapeutic signature in pancreatic cancer. Discover Oncology 2025; 16(1) doi: 10.1007/s12672-025-02873-w
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| 40 |
Shijing Tang, Hao Chen. Regulatory Role of Ribosome Biogenesis-Related Genes in Hepatocellular Carcinoma Prognosis and Construction of a Risk Prediction Model. Digestive Diseases and Sciences 2026; doi: 10.1007/s10620-026-09787-9
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| 41 |
Li Li, Junxiong Wen, Hao Xu, Hongyuan Yu, Xue Bai, Yue Zhang. ECM-responsive nanomedicine to enhance immunotherapy in pancreatic cancer. Colloids and Surfaces B: Biointerfaces 2026; 260: 115356 doi: 10.1016/j.colsurfb.2025.115356
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| 42 |
Siqi Tan, Faxiao Zhou, Xiaoming Wu. Lactate-Mediated Crosstalk Between Tumor Cells and Cancer-Associated Fibroblasts: Mechanisms and Therapeutic Opportunities. International Journal of Molecular Sciences 2025; 26(12): 5583 doi: 10.3390/ijms26125583
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| 43 |
Zhuo Song, Zhijia Sun, Yupeng Di, Xu Liu, Xiaoli Kang, Gang Ren, Yingjie Wang. Metabolic reprogramming and prognostic modeling in pancreatic cancer: insights from WGCNA. Frontiers in Genetics 2025; 16 doi: 10.3389/fgene.2025.1487046
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| 44 |
Zening Dong, Zhangchen Yuan, Tianqiang Jin, Chao Gao, Xiaoyu Wang, Feng Xu. Lactate at the crossroads of tumor metabolism and immune escape: a new frontier in cancer therapy. Journal of Translational Medicine 2025; 23(1) doi: 10.1186/s12967-025-07272-x
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| 45 |
Zixuan Gou, Qianchuang Sun, Jiannan Li. Exploring lactylation and cancer biology: insights from pathogenesis to clinical applications. Frontiers in Cell and Developmental Biology 2025; 13 doi: 10.3389/fcell.2025.1598232
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| 46 |
Xuyang Wang, Jiageng Tang, Shuyu Zhang, Xu Chen, Jie Zhang, Yi Fu. The dual faces of lactylation: From post-translational modification to disease regulation. Journal of Pharmaceutical Analysis 2026; : 101589 doi: 10.1016/j.jpha.2026.101589
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| 47 |
Wenjuan Wang, Hong Wang, Qi Wang, Xiaojing Yu, Liangliang Ouyang. Lactate-induced protein lactylation in cancer: functions, biomarkers and immunotherapy strategies. Frontiers in Immunology 2025; 15 doi: 10.3389/fimmu.2024.1513047
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| 48 |
Ying‐Chuan Yin, Jing He, Ying Feng, Yun‐yun Xu, Xiao‐hong Shi, Xue Tan, Qiao‐juan He. FiLactate‐Induced Lysine Lactylation: A Central Node Linking Metabolic Rewiring, Epigenetic Plasticity and Therapeutic Vulnerabilities in Hepatocellular Carcinoma. Journal of Biochemical and Molecular Toxicology 2025; 39(12) doi: 10.1002/jbt.70622
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| 49 |
Changlin Liu, Chuping Ni, Chao Li, Hu Tian, Weiquan Jian, Yuping Zhong, Yanqing Zhou, Xiaoming Lyu, Yuanbin Zhang, Xiao-Jun Xiang, Chao Cheng, Xin Li. Lactate-related gene signatures as prognostic predictors and comprehensive analysis of immune profiles in nasopharyngeal carcinoma. Journal of Translational Medicine 2024; 22(1) doi: 10.1186/s12967-024-05935-9
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| 50 |
Gang Nie, Zhongfei Zhu, Jing Huang, Xiaohan Shi, Xiaoyi Yin, Gang Li, Gang Jin. A mitochondria-related gene-based signature predicts pancreatic ductal adenocarcinoma clinical outcome and revealed CAMK2A/THEM4 regulates progression phenotypes and mitophagy in vivo and in vitro. Journal of Translational Medicine 2025; 24(1) doi: 10.1186/s12967-025-07456-5
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