| For: | Murray B, Barbier-Torres L, Fan W, Mato JM, Lu SC. Methionine adenosyltransferases in liver cancer. World J Gastroenterol 2019; 25(31): 4300-4319 [PMID: 31496615 DOI: 10.3748/wjg.v25.i31.4300] |
|---|---|
| URL: | https://www.wjgnet.com/1007-9327/full/v25/i31/4300.htm |
| Number | Citing Articles |
| 1 |
Lude Wang, Bin Hu, Kailing Pan, Jie Chang, Xiaoya Zhao, Lin Chen, Haiping Lin, Jing Wang, Gezhi Zhou, Wenxia Xu, Jianlie Yuan. SYVN1-MTR4-MAT2A Signaling Axis Regulates Methionine Metabolism in Glioma Cells. Frontiers in Cell and Developmental Biology 2021; 9 doi: 10.3389/fcell.2021.633259
|
| 2 |
Özlem Altundag, Betül Çelebi-Saltik. From Embryo to Adult: One Carbon Metabolism in Stem Cells. Current Stem Cell Research & Therapy 2021; 16(2) doi: 10.2174/1574888X15666200712191308
|
| 3 |
Jacqueline E. Mermoud. The Role of the m6A RNA Methyltransferase METTL16 in Gene Expression and SAM Homeostasis. Genes 2022; 13(12) doi: 10.3390/genes13122312
|
| 4 |
Pei-Yi Chu, Dev-Aur Chou, Po-Ming Chen, En-Pei Isabel Chiang. Translocation of Methionine Adenosyl Transferase MAT2A and Its Prognostic Relevance for Liver Hepatocellular Carcinoma. International Journal of Molecular Sciences 2023; 24(10) doi: 10.3390/ijms24109103
|
| 5 |
Sultan K. Alharbi, Asmaa E. Hassan, Inam Omar, Bassam M. Al-ahmadi, Maher Fathalla, Mona S. Ragab, Mohamed R. Shehata, Ahmed M. Abu-Dief. Fabrication, structural analysis, stability determination, DNA interaction, and biomedical potential of some novel water-soluble schiff base complexes. Journal of Molecular Liquids 2025; 438 doi: 10.1016/j.molliq.2025.128738
|
| 6 |
Chiara Raggi, Maria Letizia Taddei, Colin Rae, Chiara Braconi, Fabio Marra. Metabolic reprogramming in cholangiocarcinoma. Journal of Hepatology 2022; 77(3) doi: 10.1016/j.jhep.2022.04.038
|
| 7 |
Pei-wen Yang, Ju-ying Jiao, Zhen Chen, Xiao-yan Zhu, Chien-shan Cheng. Keep a watchful eye on methionine adenosyltransferases, novel therapeutic opportunities for hepatobiliary and pancreatic tumours. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2022; 1877(5) doi: 10.1016/j.bbcan.2022.188793
|
| 8 |
Bing Yang, Liqing Lu, Jiaohong Wang, Lucía Barbier-Torres, Jing Zhang, Jyoti Chhimwal, Sonal Sinha, Brent Beadell, Guo Zhang, Takashi Tsuchiya, Maria Lauda Tomasi, Ting Liu, Heping Yang, Shelly C. Lu. Forkhead box protein M1 network induction and crosstalk drives the development of alcohol-associated liver disease. Hepatology 2026; doi: 10.1097/HEP.0000000000001753
|
| 9 |
Lucía Barbier-Torres, Shelly C Lu. Prohibitin 1 in liver injury and cancer. Experimental Biology and Medicine 2020; 245(5) doi: 10.1177/1535370220908257
|
| 10 |
Nan Fang, Bing Liu, Qiuzhong Pan, Tingting Gong, Meixiao Zhan, Jingjing Zhao, Qijing Wang, Yan Tang, Yongqiang Li, Jia He, Tong Xiang, Fengze Sun, Ligong Lu, Jianchuan Xia. SMG5 Inhibition Restrains Hepatocellular Carcinoma Growth and Enhances Sorafenib Sensitivity. Molecular Cancer Therapeutics 2024; 23(8) doi: 10.1158/1535-7163.MCT-23-0729
|
| 11 |
Rebecca L. Koch, James B. Stanton, Susan McClatchy, Gary A. Churchill, Steven W. Craig, Darian N. Williams, Mallory E. Johns, Kylah R. Chase, Dana L. Thiesfeldt, Jessica C. Flynt, Robert Pazdro. Discovery of genomic loci for liver health and steatosis reveals overlap with glutathione redox genetics. Redox Biology 2024; 75 doi: 10.1016/j.redox.2024.103248
|
| 12 |
Amina Doudou Tellai, Vincent Haghnejad, Justine Antoine, Basma Khemiri Merouani, Jean-Pierre Bronowicki, Natacha Dreumont. The complex post-transcriptional regulation of genes coding for methionine adenosyl transferase: New insights for liver cancer. Biochimie 2025; 238 doi: 10.1016/j.biochi.2025.05.001
|
| 13 |
Rosa M. Pascale, Maria M. Simile, Diego F. Calvisi, Claudio F. Feo, Francesco Feo. S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent. Cells 2022; 11(3) doi: 10.3390/cells11030409
|
| 14 |
Jianwen Jiang, Qiuxian Zheng, Weiwei Zhu, Xinhua Chen, Haifeng Lu, Deying Chen, Hua Zhang, Min Shao, Lin Zhou, Shusen Zheng. Alterations in glycolytic/cholesterogenic gene expression in hepatocellular carcinoma. Aging 2020; 12(11) doi: 10.18632/aging.103254
|
| 15 |
Yee Hui Yeo, Manal Abdelmalek, Seema Khan, Cynthia A. Moylan, Luz Rodriquez, Augusto Villanueva, Ju Dong Yang. Current and emerging strategies for the prevention of hepatocellular carcinoma. Nature Reviews Gastroenterology & Hepatology 2025; 22(3) doi: 10.1038/s41575-024-01021-z
|
| 16 |
Rocío Matesanz-Sánchez, Mirko Peitzsch, Inga Lange, Jovan Mircetic, Michael Seifert, Nils Cordes, Anne Vehlow. A novel role of exostosin glycosyltransferase 2 (EXT2) in glioblastoma cell metabolism, radiosensitivity and ferroptosis. Cell Death & Differentiation 2025; 32(9) doi: 10.1038/s41418-025-01503-w
|
| 17 |
Urszula Głowacka, Tomasz Brzozowski, Marcin Magierowski. Synergisms, Discrepancies and Interactions between Hydrogen Sulfide and Carbon Monoxide in the Gastrointestinal and Digestive System Physiology, Pathophysiology and Pharmacology. Biomolecules 2020; 10(3) doi: 10.3390/biom10030445
|
| 18 |
Christophe Desterke, Raquel Francés, Claudia Monge, Yuanji Fu, Agnès Marchio, Pascal Pineau, Jorge Mata-Garrido. Single-cell RNAseq reveals adverse metabolic transcriptional program in intrahepatic cholangiocarcinoma malignant cells. Biochemistry and Biophysics Reports 2025; 41 doi: 10.1016/j.bbrep.2025.101949
|
| 19 |
Bing Yang, Liqing Lu, Ting Xiong, Wei Fan, Jiaohong Wang, Lucía Barbier-Torres, Jyoti Chhimwal, Sonal Sinha, Takashi Tsuchiya, Nirmala Mavila, Maria Lauda Tomasi, DuoYao Cao, Jing Zhang, Hui Peng, José M. Mato, Ting Liu, Xi Yang, Vladimir V. Kalinichenko, Komal Ramani, Jenny Han, Ekihiro Seki, Heping Yang, Shelly C. Lu. The role of forkhead box M1-methionine adenosyltransferase 2 A/2B axis in liver inflammation and fibrosis. Nature Communications 2024; 15(1) doi: 10.1038/s41467-024-52527-8
|
| 20 |
Nora S. Mohamed, Mahmoud M. A. Mohamed, Mohamed R. Shehata, Ehab M. Abdalla. Lanthanide–carbamazepine complexes: synthesis, spectroscopic characterization, DFT Insights, molecular docking, and biological evaluation. Scientific Reports 2026; 16(1) doi: 10.1038/s41598-026-35893-9
|
| 21 |
Siyu Cai, Yuan Su, Mengtian Shi, Dandan Wang, David Da Yong Chen, Binjun Yan. Simultaneous quantification of six proteins related to liver injury using nano liquid chromatography–tandem mass spectrometry. Rapid Communications in Mass Spectrometry 2024; 38(12) doi: 10.1002/rcm.9754
|
| 22 |
L.L. Pinsky. NON-ALCOHOLIC FATTY LIVER DISEASE IN PROCEEDINGS OF CONGRESS EASL – 2023. Medical Science of Ukraine (MSU) 2023; 19(4) doi: 10.32345/2664-4738.4.2023.17
|
| 23 |
Xing He, Yuqin Gu, Guangyu Lu, Linxue Zhang, Xue Yang, Ziheng Kan, Yuwei Li, RuiJi Liu, Xianjun Zhu, Zhenglin Yang, Ziyan Wang. Reprogramming cysteine metabolism via METTL14-SLC7A11 axis promotes the progression of NAFLD and hepatocellular carcinoma. Life Sciences 2025; 380 doi: 10.1016/j.lfs.2025.123965
|
| 24 |
Yuqing Ren, Di Tang, Xiaofan Ding, Mian He. Crosstalk Between Cis-Regulatory Elements and Metabolism Reprogramming in Hepatocellular Carcinoma. Cancers 2026; 18(6) doi: 10.3390/cancers18061002
|
| 25 |
Shun Zhang, Yuan-Yuan Zhang, Qiu-Xia Zeng, Li Wang, Kong-Xian Li, Qi Chen. Quercetin Inhibits Ectopic Lesion Formation in Mice by Modulating the MAT2A/PRMT5 Pathway through PPARγ Activation. Combinatorial Chemistry & High Throughput Screening 2025; 29 doi: 10.2174/0113862073379671250219103011
|
| 26 |
Laura Mosca, Francesca Vitiello, Luigi Borzacchiello, Alessandra Coppola, Roberta Veglia Tranchese, Martina Pagano, Michele Caraglia, Giovanna Cacciapuoti, Marina Porcelli. Mutual Correlation between Non-Coding RNA and S-Adenosylmethionine in Human Cancer: Roles and Therapeutic Opportunities. Cancers 2021; 13(13) doi: 10.3390/cancers13133264
|
| 27 |
Zhanghao Li, Feixia Wang, Baoyu Liang, Ying Su, Sumin Sun, Siwei Xia, Jiangjuan Shao, Zili Zhang, Min Hong, Feng Zhang, Shizhong Zheng. Methionine metabolism in chronic liver diseases: an update on molecular mechanism and therapeutic implication. Signal Transduction and Targeted Therapy 2020; 5(1) doi: 10.1038/s41392-020-00349-7
|
| 28 |
Jie Liu, Jun Huang, Peikun Xin, Guiting Liu, Jun Wu. Biomedical applications of methionine-based systems. Biomaterials Science 2021; 9(6) doi: 10.1039/D0BM02180F
|
| 29 |
Faisal T. Khaja, Reedhi Vara, Louie P. Aspinall, Ciara Merriman, Alana Maerivoet, Joshua B. R. White, Stephen P. Muench, S. Samar Hasnain, S. V. Antonyuk. CryoEM structures reveal allosteric regulation of the catalytic activity of the multi-protein human MAT enzyme complexes. IUCrJ 2026; 13(4) doi: 10.1107/S2052252526005075
|
| 30 |
María R. Luque-Urbano, David Fernández-Ramos, Fernando Lopitz-Otsoa, Virginia Gutiérrez de Juan, Maider Bizkarguenaga, Lia Castro-Espadas, Uxue Hermoso-Martínez, Lucía Barbier-Torres, Shelly C. Lu, Oscar Millet, José M. Mato. S-adenosylmethionine deficit disrupts very low-density lipoprotein metabolism promoting liver lipid accumulation in mice. Journal of Lipid Research 2025; 66(5) doi: 10.1016/j.jlr.2025.100794
|
| 31 |
Jiaxiang Luo, Yang Li, Yiwen Zhang, Defa Wu, Yijiu Ren, Jie Liu, Chengdi Wang, Jifa Zhang. An update on small molecule compounds targeting synthetic lethality for cancer therapy. European Journal of Medicinal Chemistry 2024; 278 doi: 10.1016/j.ejmech.2024.116804
|
| 32 |
Sijia Hua, Fan Fei, Jiawen Li, Yuting Liu, Yuhong Gao, Xiang Wang, Xiulin Dong, Qiang Liu, Jianfeng Yang. Amino acid metabolic reprogramming: future prospects for cholangiocarcinoma therapy. Cell Death Discovery 2026; 12(1) doi: 10.1038/s41420-025-02843-9
|
| 33 |
Sang-Woon Choi, Simonetta Friso. Modulation of DNA methylation by one-carbon metabolism: a milestone for healthy aging. Nutrition Research and Practice 2023; 17(4) doi: 10.4162/nrp.2023.17.4.597
|
| 34 |
Nasser Farhan, Rehab S. Abo-Rehab, Mohamed R. Shehata, Ahmed M. Abu-Dief, RA El-Kasaby, Maher Fathalla, Samar A. Aly, Ensaf Aboul Kasim, Ehab M. Abdalla. Engineered for impact: Multifunctional Co(II), Ni(II), Cu(II), and Cd(II) complexes of 2-aminobenzothiazole with potent antitumor, antibacterial, and antioxidant actions supported by theoretical approaches. Journal of Molecular Structure 2026; 1351 doi: 10.1016/j.molstruc.2025.144295
|
| 35 |
Laura Mosca, Francesca Vitiello, Martina Pagano, Alessandra Coppola, Roberta Veglia Tranchese, Roberta Grillo, Giovanna Cacciapuoti, Marina Porcelli. S-Adenosylmethionine, a Promising Antitumor Agent in Oral and Laryngeal Cancer. Applied Sciences 2022; 12(3) doi: 10.3390/app12031746
|
| 36 |
Xiao Han, Tianren Huang, Qiang Li, Junqing Han, Xiaoling Luo. Preliminary study on establishing the discriminant equation in pathological grading of hepatocellular carcinoma using immunohistochemical marker parameters. Journal of Cancer Research and Therapeutics 2022; 18(5) doi: 10.4103/jcrt.jcrt_2021_21
|
| 37 |
Rehab S. Abo‐Rehab, Ensaf Aboul Kasim, Nasser Farhan, Mahmoud S. Tolba, Mohamed R. Shehata, Ehab M. Abdalla. Synthesis, characterization, anticancer, antibacterial, antioxidant, DFT, and molecular docking of novel La (III), Ce (III), Nd (III), and Dy (III) lanthanide complexes with Schiff base derived from 2‐aminobenzothiazole and coumarin. Applied Organometallic Chemistry 2024; 38(9) doi: 10.1002/aoc.7622
|
| 38 |
Ahmed M. Abu-Dief, Mohamed R. Shehata, Asmaa E. Hassan, Sultan K. Alharbi, Abdullah Yahya Abdullah Alzahrani, Hala M. Abo-Dief, Mona S. Ragab. Exploring, anthranilic azomethine complexes: from synthesis, spectroscopic, solution and theoretical studies to DNA interaction and biomedical prospects. Journal of Molecular Structure 2025; 1341 doi: 10.1016/j.molstruc.2025.142571
|
| 39 |
Christos Chinopoulos. Mitochondrial respiration supports cancer growth independent of OXPHOS. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2026; 1881(3) doi: 10.1016/j.bbcan.2026.189593
|
| 40 |
Modan Yang, Winyen Tan, Xinyu Yang, Jianyong Zhuo, Zuyuan Lin, Beini Cen, Zhengxing Lian, Huihui Li, Di Lu, Xuyong Wei, Shusen Zheng, Xiao Xu. Homocysteine: A novel prognostic biomarker in liver transplantation for alpha-fetoprotein- negative hepatocellular carcinoma. Cancer Biomarkers 2020; 29(2) doi: 10.3233/CBM-201545
|
| 41 |
Wei Fan, DuoYao Cao, Bing Yang, Jiaohong Wang, Xiaomo Li, Diana Kitka, Tony W.H. Li, Sungyong You, Stephen Shiao, Alexandra Gangi, Edwin Posadas, Dolores Di Vizio, Maria Lauda Tomasi, Ekihiro Seki, José M. Mato, Heping Yang, Shelly C. Lu. Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis. Journal of Hepatology 2024; 80(3) doi: 10.1016/j.jhep.2023.11.022
|
| 42 |
Ran Zhou, Yuejun Li, Guanghui Li, Yan Li, Lie Luo, Bin Wang, Liping Wang. Metabolic characteristics in hepatocellular carcinoma: amino acid metabolic reprogramming. Molecular Cancer 2026; 25(1) doi: 10.1186/s12943-025-02492-7
|
| 43 |
Menghui Xu, Ruhao Zhuo, Shengxiang Tao, Yaxu Liang, Chunru Liu, Qingyang Liu, Tian Wang, Xiang Zhong. M6A RNA Methylation Mediates NOD1/NF-kB Signaling Activation in the Liver of Piglets Challenged with Lipopolysaccharide. Antioxidants 2022; 11(10) doi: 10.3390/antiox11101954
|
| 44 |
Qi Zhang, Wei Li. Correlation between amino acid metabolism and self-renewal of cancer stem cells: Perspectives in cancer therapy. World Journal of Stem Cells 2022; 14(4): 267-286 doi: 10.4252/wjsc.v14.i4.267
|
| 45 |
Lishan Jiang, Jingwen Li, Kun Ji, Lang Lei, Houxuan Li.
MAT2A inhibition suppresses inflammation in
Porphyromonas gingivalis
-infected human gingival fibroblasts
. Journal of Oral Microbiology 2024; 16(1) doi: 10.1080/20002297.2023.2292375
|
| 46 |
Yu Zhang, Pengfei Wang, Zhicheng Xie, Yilun Huang, Yaqi Ding, Jia Liu, Yi Chen, Youhong Hu. Design and Discovery of Pyridazinone-Based MAT2A Inhibitors Targeting MTAP-Deficient Cancers. Journal of Medicinal Chemistry 2026; 69(9) doi: 10.1021/acs.jmedchem.5c03074
|
| 47 |
Hong Lin, Juan I. Luengo. Exploiting binding-site arginines in drug design: Recent examples. Bioorganic & Medicinal Chemistry Letters 2020; 30(19) doi: 10.1016/j.bmcl.2020.127442
|
| 48 |
Navzer D. Sachinvala, Naozumi Teramoto, Angeline Stergiou. Proposed Neuroimmune Roles of Dimethyl Fumarate, Bupropion, S-Adenosylmethionine, and Vitamin D3 in Affording a Chronically Ill Patient Sustained Relief from Inflammation and Major Depression. Brain Sciences 2020; 10(9) doi: 10.3390/brainsci10090600
|
| 49 |
Manal A. Afifi, Anas A. Rasmy, Emad M. Elzayat, Samir M. El-Medani, Mohamed R. Shehata, Fatma M. Elantabli. Spectroscopic, docking, antiproliferative, and anticancer activity of novel metal derivatives of phenylacetohydrazide Schiff base on different human cancer cell lines. BMC Chemistry 2025; 19(1) doi: 10.1186/s13065-025-01417-1
|
| 50 |
Monica Justo, Youngyi Lim, Heping Yang, Andrea Floris, Swati Chandla, Manisha Dagar, Alexandra Gangi, Edwin Posadas, Mouad Edderkaoui, Stephen Pandol, Neil Bhowmick, Maria Lauda Tomasi, Shelly C. Lu. A novel role of secreted methionine adenosyltransferase α2 in colorectal liver metastases. Journal of Experimental & Clinical Cancer Research 2025; 45(1) doi: 10.1186/s13046-025-03599-x
|
| 51 |
Feng Jiang, Qiang Shen, Fan Zhang, Jiali Fu, Lijuan Hu, Junjun Wang, Huixin Zhou, Jian Chen, Yumin Wang. ADH1C Facilitates Cisplatin Resistance of Lung Adenocarcinoma Cells. DNA and Cell Biology 2022; 41(6) doi: 10.1089/dna.2021.0877
|
| 52 |
Reem M. Alghanmi, Maram T. Basha, Ahlam I. Al-Sulami, Saied M. Soliman, Laila H. Abdel-Rahman. A New Proton Transfer Complex Between 3,4-Diaminopyridine Drug and 2,6-Dichloro-4-nitrophenol: Synthesis, Spectroscopic Characterization, DFT Studies, DNA Binding Analysis, and Antitumor Activity. Molecules 2024; 29(21) doi: 10.3390/molecules29215120
|
| 53 |
Jiaxin Chen, Huiling Zuo, Yuhang Jiao, Huanhuan Zhao, Xuan Ma, Yahui Xiao, Xiangqiong Li, Wei Zhao, Anhua Shi, Wenhui Chen. Effect of gentiopicroside on endogenous formaldehyde homocysteine–pathway related proteins in rats with non-alcoholic steatohepatitis. Frontiers in Pharmacology 2026; 16 doi: 10.3389/fphar.2025.1700101
|
| 54 |
Anna M Scarborough, Juliana N Flaherty, Olga V Hunter, Kuanqing Liu, Ashwani Kumar, Chao Xing, Benjamin P Tu, Nicholas K Conrad. SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A. eLife 2021; 10 doi: 10.7554/eLife.64930
|
| 55 |
Xiu Zang, Yankun Yang, Chunjun Zhan, Zhonghu Bai. Blocking methanol dissimilation pathway and incorporating RuMP to increase methanol utility in Komagataella phaffii. Systems Microbiology and Biomanufacturing 2025; 5(3) doi: 10.1007/s43393-025-00356-1
|
| 56 |
Russell R. Fling, Claire M. Doskey, Kelly A. Fader, Rance Nault, Tim R. Zacharewski. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice. Scientific Reports 2020; 10(1) doi: 10.1038/s41598-020-71795-0
|
| 57 |
Maierhaba Wusiman, Si-Yu Huang, Zhao-Yan Liu, Tong-Tong He, Ai-Ping Fang, Meng-Chu Li, Meng-Tao Yang, Chen Wang, Yao-Jun Zhang, Hui-Lian Zhu. Serum S-adenosylhomocysteine, rather than homocysteine, is associated with hepatocellular carcinoma survival: a prospective cohort study. The American Journal of Clinical Nutrition 2024; 120(3) doi: 10.1016/j.ajcnut.2024.07.014
|
| 58 |
Xueer Du, Lamei Wang, Yanfei Dai, Jing Lu, Hongrui Li, Dangdang Wang, Jun Zhang, Chuanjiang Cai, Shimin Liu, Junhu Yao, Jianguo Wang, Yangchun Cao. Choline attenuates NEFA-induced hepatic steatosis via GNMT regulation in hepatocytes. Stress Biology 2025; 5(1) doi: 10.1007/s44154-025-00264-3
|
| 59 |
Bang-Qi Wang, Xu-Chu Li, Zhenyu Huo, Kai Zeng, Shen Chen, Yuning Wang, Yiming Zhu, Yuyang Huang, Jiatong Ding, Yuanting Cai, Ning Li, Yu Tang. Unraveling the potential of targeting methionine metabolism in cancer. Cancer Letters 2026; 644 doi: 10.1016/j.canlet.2026.218338
|
| 60 |
Sai Yang, Xiaowen Gu, Lei Chen, Weixing Zhu. Discovery of Novel Spirocyclic MAT2A Inhibitors Demonstrating High In Vivo Efficacy in MTAP-Null Xenograft Models. Journal of Medicinal Chemistry 2025; 68(3) doi: 10.1021/acs.jmedchem.4c02634
|
| 61 |
Liqing Lu, Jing Zhang, Wei Fan, Yuan Li, Jiaohong Wang, Tony W. H. Li, Lucia Barbier-Torres, José M. Mato, Ting Liu, Ekihiro Seki, Michitaka Matsuda, Maria Lauda Tomasi, Neil A. Bhowmick, Heping Yang, Shelly C. Lu. Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans. Oncogene 2021; 40(39) doi: 10.1038/s41388-021-01980-6
|
| 62 |
Valentina Fogal, Filippos Michopoulos, Andrew F. Jarnuczak, Ghaith M. Hamza, Stephanie Harlfinger, Paul Davey, Heather Hulme, Stephen J. Atkinson, Piotr Gabrowski, Tony Cheung, Michael Grondine, Clare Hoover, Jonathan Rose, Chandler Bray, Alison J. Foster, Sean Askin, Muntasir Mamun Majumder, Paul Fitzpatrick, Eric Miele, Ruth Macdonald, Hector C. Keun, Muireann Coen. Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition. Archives of Toxicology 2024; 98(8) doi: 10.1007/s00204-024-03771-w
|
| 63 |
Shengping Shen, Ruili Liu, Jiazheng Huang, Yingjia Sun, Qiang Tan, Qingquan Luo, Ruijun Liu. MAT1A activation of glycolysis to promote NSCLC progression depends on stabilizing CCND1. Cell Death & Disease 2024; 15(10) doi: 10.1038/s41419-024-07113-7
|
| 64 |
Tarek Kamal Abouzed, Fayez Althobaiti, Nesreen Adel Abdelkhlek, Ehab Bedir Eldomany, Nasr Elsayed Nasr, Kadry Mohamed Sadek, Samir Ahmed El-Shazly, Khaled A. Kahilo, Doaa Abdallha Dorghamm. Antitumor and Antioxidant Activity of S-Methyl Methionine Sulfonium Chloride against Liver Cancer Induced in Wistar Albino Rats by Diethyl Nitrosamine and Carbon Tertrachloride. International Journal of Environmental Research and Public Health 2021; 18(18) doi: 10.3390/ijerph18189726
|
| 65 |
Kyla Young, Allison K. Tscherner, Baohua Zhang, Megan Meredith, Taylor McClatchie, Jacquetta M. Trasler, Jay M. Baltz. 5,10-Methylenetetrahydrofolate reductase becomes phosphorylated during meiotic maturation in mouse oocytes. Zygote 2022; 30(5) doi: 10.1017/S0967199422000156
|
| 66 |
Feng Gao, Xiaoyu Ding, Zhongying Cao, Wei Zhu, Yaya Fan, Barbara Steurer, Hailong Wang, Xin Cai, Man Zhang, Alex Aliper, Feng Ren, Xiao Ding, Alex Zhavoronkov. Discovery of novel MAT2A inhibitors by an allosteric site-compatible fragment growing approach. Bioorganic & Medicinal Chemistry 2024; 100 doi: 10.1016/j.bmc.2024.117633
|
| 67 |
Mauricio Díaz-Muñoz, Rolando Hernández-Muñoz, Armando Butanda-Ochoa. Structure–activity features of purines and their receptors: implications in cell physiopathology. Molecular Biomedicine 2022; 3(1) doi: 10.1186/s43556-022-00068-1
|
| 68 |
Adwait A Godbole, Sneha Gopalan, Thien-Kim Nguyen, Alexander L Munden, Dominique S Lui, Matthew J Fanelli, Paula Vo, Caroline A Lewis, Jessica B Spinelli, Thomas G Fazzio, Amy K Walker. S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress. eLife 2023; 12 doi: 10.7554/eLife.79511
|
| 69 |
Na Sun, Yuchuan Zhang, Jian Dong, Geng Liu, Zhenbin Liu, Jiamin Wang, Zilin Qiao, Jiayou Zhang, Kai Duan, Xuanxuan Nian, Zhongren Ma, Xiaoming Yang. Metabolomics profiling reveals differences in proliferation between tumorigenic and non-tumorigenic Madin-Darby canine kidney (MDCK) cells. PeerJ 2023; 11 doi: 10.7717/peerj.16077
|
| 70 |
Lucía Barbier-Torres, Jyoti Chhimwal, José M. Mato, Shelly C. Lu. Methionine Adenosyltransferase 1A and S-Adenosylmethionine in Alcohol-Associated Liver Disease. Antioxidants 2025; 14(12) doi: 10.3390/antiox14121486
|
| 71 |
Yaqin Li, Guoxin Hu, Furong Huang, Mingtai Chen, Yihua Chen, Youhua Xu, Guangdong Tong. MAT1A Suppression by the CTBP1/HDAC1/HDAC2 Transcriptional Complex Induces Immune Escape and Reduces Ferroptosis in Hepatocellular Carcinoma. Laboratory Investigation 2023; 103(8) doi: 10.1016/j.labinv.2023.100180
|
| 72 |
Mian‐Feng Yao, Meng‐Ying Shao, Qiu‐Lan Li, Tian‐Ru Yang, Zi‐Ran Zheng, Xin‐Le Zhang, Jia‐Jun Huang, Yuan‐Xin Sun, Jing He, Jiang Li, Chang‐Yun Fang. miR‐134‐3p Deficiency‐Induced Methionine Metabolism Promotes Fibrosis via SLC25A33 in OSF. Journal of Oral Pathology & Medicine 2025; 54(7) doi: 10.1111/jop.70003
|
| 73 |
Chunzheng Li, Gang Gui, Li Zhang, Anqi Qin, Chen Zhou, Xiaoming Zha. Overview of Methionine Adenosyltransferase 2A (MAT2A) as an Anticancer Target: Structure, Function, and Inhibitors. Journal of Medicinal Chemistry 2022; 65(14) doi: 10.1021/acs.jmedchem.2c00395
|
| 74 |
Alba Capelo-Diz, Sofía Lachiondo-Ortega, David Fernández-Ramos, Jorge Cañas-Martín, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Maria J. González-Rellan, Laura Mosca, Joan Blazquez-Vicens, Alberto Tinahones-Ruano, Marcos F. Fondevila, Mason Buyan, Teresa C. Delgado, Virginia Gutierrez de Juan, Paula Ayuso-García, Alejandro Sánchez-Rueda, Sergio Velasco-Avilés, Héctor Fernández-Susavila, Cristina Riobello-Suárez, Bartlomiej Dziechciarz, Cristina Montiel-Duarte, Fernando Lopitz-Otsoa, Maider Bizkarguenaga, Jon Bilbao-García, Ganeko Bernardo-Seisdedos, Ana Senra, Mario Soriano-Navarro, Oscar Millet, Ángel Díaz-Lagares, Ana B. Crujeiras, Aida Bao-Caamano, Diana Cabrera, Sebastiaan van Liempd, Miguel Tamayo-Caro, Luigi Borzacchiello, Beatriz Gomez-Santos, Xabier Buqué, Diego Sáenz de Urturi, Francisco González-Romero, Jorge Simon, Rubén Rodríguez-Agudo, Asier Ruiz, Carlos Matute, Daniel Beiroa, Juan M. Falcon-Perez, Patricia Aspichueta, Juan Rodríguez-Cuesta, Marina Porcelli, María A. Pajares, Cristina Ameneiro, Miguel Fidalgo, Ana M. Aransay, Tomas Lama-Díaz, Miguel G. Blanco, Miguel López, Ricardo Villa-Bellosta, Timo D. Müller, Rubén Nogueiras, Ashwin Woodhoo, María Luz Martínez-Chantar, Marta Varela-Rey. Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting. Cell Metabolism 2023; 35(8) doi: 10.1016/j.cmet.2023.07.002
|
| 75 |
Ahmed M. Abu-Dief, Mohamed R. Shehata, Asmaa E. Hassan, Bader M. Altayeb, Faizah S. Aljohani, Ibrahim Omar Barnawi, Hala M. Abo-Dief, Mona S. Ragab. Tailoring of novel water soluble Pd(II), Cu(II), Fe(III) and VO(II) chelates based on 4-[(5-bromo-2-hydroxy-benzylidene)-amino]-benzenesulfonate ligand: Synthesis, spectral investigations, DNA interaction and pharmaceutical applications supported by molecular docking approach. Journal of Molecular Structure 2025; 1334 doi: 10.1016/j.molstruc.2025.141780
|
| 76 |
Mengying Liu, Nirmalya Saha, Ambikai Gajan, Nadia Saadat, Smiti V. Gupta, Lori A. Pile. A complex interplay between SAM synthetase and the epigenetic regulator SIN3 controls metabolism and transcription. Journal of Biological Chemistry 2020; 295(2) doi: 10.1074/jbc.RA119.010032
|