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For: Chen BF. Hepatitis B virus pre-S/S variants in liver diseases. World J Gastroenterol 2018; 24(14): 1507-1520 [PMID: 29662289 DOI: 10.3748/wjg.v24.i14.1507]
URL: https://www.wjgnet.com/1007-9327/full/v24/i14/1507.htm
Number Citing Articles
1
Yurong Zou, Sipei Chen, Yiyuan Cui, Yang Zou. M133S mutation possibly involve in the ER stress and mitophagy pathway in maintenance hemodialysis patients with occult hepatitis B infectionScientific Reports 2024; 14(1) doi: 10.1038/s41598-024-64943-3
2
Arwa Bagasi, Fatimah Alghnnam, Marie Bohol, Fatimah Alhamlan, Arwa Al-Qahtani, Hani Alothaid, Ayman Abdo, Faisal Sanai, Ahmad Al-Qahtani. Mutational landscape of the surface antigen of hepatitis B virus in patients with hepatocellular carcinomaGut Pathogens 2025; 17(1) doi: 10.1186/s13099-025-00719-y
3
Camilla Rodrigues de Almeida Ribeiro, Katrini Guidolini Martinelli, Vinícius da Motta de Mello, Natália Spitz, Oscar Rafael Carmo Araújo, Lia Laura Lewis-Ximenez, Natalia Motta Araujo, Vanessa Salete de Paula. Association of Pre-S/S and Polymerase Mutations with Acute and Chronic Hepatitis B Virus Infections in Patients from Rio de Janeiro, BrazilViruses 2022; 14(7): 1375 doi: 10.3390/v14071375
4
Wenbin Liu, Guangwen Cao. Hepatocellular Carcinoma - Challenges and Opportunities of a Multidisciplinary Approach2022;  doi: 10.5772/intechopen.99838
5
Shahrzad Shoraka, Seyed Mahdi Hosseinian, Ayda Hasibi, Amir Ghaemi, Seyed Reza Mohebbi. The role of hepatitis B virus genome variations in HBV-related HCC: effects on host signaling pathwaysFrontiers in Microbiology 2023; 14 doi: 10.3389/fmicb.2023.1213145
6
Haofeng Yin, Yibo Xue, Chen Wang, Yanqin Wu, Yuchen Guo, Chunzhen Li, Yunyan Zhang, Shulei Yin, Tiejun Zhao. UBE2N as a novel prognostic and therapeutic biomarker of lung adenocarcinomaFrontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1636503
7
Xiaoying Zhang, Liping You, Yuting Bi, Chao Gu, Xiaoni Kong, Yueqiu Gao, xuehua Sun. Clinical Implications of Surface Protein-Mutations Outside the Major Hydrophilic Region of Hepatitis B Virus Among Chinese PatientsSSRN Electronic Journal 2022;  doi: 10.2139/ssrn.4193842
8
Hiba Sami, Mohd Asaad, Syed Haider Mehdi Husaini, Parvez Anwar Khan, Adil Raza, Nazish Fatima, Haris M. Khan. HBV genotype distribution and S gene mutations in HIV-HBV co-infected patients: insights from North IndiaFrontiers in Cellular and Infection Microbiology 2026; 15 doi: 10.3389/fcimb.2025.1731472
9
Chao Lu, Wanjin Fu, Renpeng Zhou, Wei Hu. Network pharmacology-based study on the mechanism of Yiganling capsule in hepatitis B treatmentBMC Complementary Medicine and Therapies 2020; 20(1) doi: 10.1186/s12906-020-2815-y
10
Jing-Jing Han, Yu-An Hu, Yuchen Nan, Yu Chen, Yong-Lin Yang. Decreased expression of HBV surface antigen (HBsAg) with sK122R and sV96A co-mutation is associated with an ineffective antibody response in a chronic hepatitis B patientInfection, Genetics and Evolution 2023; 111: 105431 doi: 10.1016/j.meegid.2023.105431
11
Shuling Wu, Liu Yang, Xiaoyue Bi, Yanjie Lin, Wen Deng, Tingting Jiang, Minghui Li, Yao Xie. Attach importance to antiviral therapy in patients with hepatocellular carcinoma caused by hepatitis virusGastroenterology & Endoscopy 2023; 1(1): 5 doi: 10.1016/j.gande.2022.10.001
12
Yaseen I. Mamoori, Ibrahim A. Ahmed, Ayhan R. Mahmood, Safaa A. Al-Waysi, Ahmed Majeed Al-Shammari. Full‐Length Genome Sequencing and Analysis of Hepatitis B Viruses Isolated from Iraqi PatientsInternational Journal of Microbiology 2024; 2024(1) doi: 10.1155/2024/6826495
13
Citrawati Dyah Kencono Wungu, Fis Citra Ariyanto, Gwenny Ichsan Prabowo, Soetjipto Soetjipto, Retno Handajani. Meta‐analysis: Association between hepatitis B virus preS mutation and hepatocellular carcinoma riskJournal of Viral Hepatitis 2021; 28(1): 61 doi: 10.1111/jvh.13402
14
Iraj Shahramian, Pouya Ostadrahimi, Mahboobeh Sheikh, Somayeh Nazari, Hadi Mirzarie, Abdolvahab Moradi, Alireza Aminisefat, Ali Bazi, Feteme Parooie, Masoud Tahani. Evaluation of S Gene Mutations in Children with Maternally Transmitted Hepatitis BJournal of Advances in Medical and Biomedical Research 2023; 31(144): 57 doi: 10.30699/jambs.31.144.57
15
Chisa Kobayashi, Toru Ekimoto, Koji Ooka, Junki Mifune, Kayo Matsuzawa, Lusheng Que, Yingfang Li, Atsuto Kusunoki, Takeshi Morita, Kaho Shionoya, Makoto Nagano, Kousho Wakae, Masanori Isogawa, Masamichi Muramatsu, Umeharu Ohto, Norimichi Nomura, Sam-Yong Park, Camille Sureau, Munehito Arai, Mitsunori Ikeguchi, Koichi Watashi. Multistep receptor binding of the hepatitis B virus preS1 domainNature Communications 2026; 17(1) doi: 10.1038/s41467-025-68062-z
16
Huizhen Sun, Le Chang, Ying Yan, Huimin Ji, Xinyi Jiang, Shi Song, Yingzi Xiao, Zhuoqun Lu, Lunan Wang. Naturally occurring pre-S mutations promote occult HBV infection by affecting pre-S2/S promoter activityAntiviral Research 2022; 208: 105448 doi: 10.1016/j.antiviral.2022.105448
17
Yuh‐Jin Liang, Wei Teng, Chih‐Li Chen, Cheng‐Pu Sun, Rui‐Dung Teng, Yen‐Hua Huang, Kung‐Hao Liang, Yi‐Wen Chen, Chung‐Chih Lin, Chien‐Wei Su, Mi‐Hua Tao, Jaw‐Ching Wu. Clinical Implications of HBV PreS/S Mutations and the Effects of PreS2 Deletion on Mitochondria, Liver Fibrosis, and Cancer DevelopmentHepatology 2021; 74(2): 641 doi: 10.1002/hep.31789
18
Patcharin Tepjanta, Kazuhito Fujiyama, Ryo Misaki, Ingorn Kimkong, Benjamin M. Liu. The N-linked glycosylation modifications in the hepatitis B surface protein impact cellular autophagy, HBV replication, and HBV secretionPLOS ONE 2024; 19(3): e0299403 doi: 10.1371/journal.pone.0299403
19
Florence Cindibu Kalonji, Yu Nakagama, Evariste Tshibangu-Kabamba, Nadine Kayiba Kalenda, Shun Nakagama, Sachie Nakagama, Pathy Kamanga Nkolongo, Nestor Kalala-Tshituka, Alphonse Lufuluabu Mpemba, Faustin Ndjibu Mpoji, André Kabongu Kalala, Benjamin Muamba Mpoyi, Dieudonné Mumba Ngoyi, Natsuko Kaku, Yusuke Shimakawa, Ghislain Tumba Disashi, Yasutoshi Kido. Intra-familial transmission of Hepatitis B virus in a peri-urban community from the Democratic Republic of the CongoTropical Medicine and Health 2025; 53(1) doi: 10.1186/s41182-025-00781-x
20
Xianglong Lan, Yurou Wang, Min Liao, Linghua Li, Fengyu Hu. Hepatitis B Virus PreS-Mutated Strains in People Living with HIV: Long-Term Hepatic Outcomes Following ART InitiationViruses 2025; 17(8): 1102 doi: 10.3390/v17081102
21
Carlo Saitta, Teresa Pollicino, Giovanni Raimondo. Occult Hepatitis B Virus Infection: An UpdateViruses 2022; 14(7): 1504 doi: 10.3390/v14071504
22
Dina Kremsdorf, Bouchra Lekbaby, Pierre Bablon, Jules Sotty, Jérémy Augustin, Aurélie Schnuriger, Jonathan Pol, Patrick Soussan. Alternative splicing of viral transcripts: the dark side of HBVGut 2021; 70(12): 2373 doi: 10.1136/gutjnl-2021-324554
23
Ivana Lazarevic, Ana Banko, Danijela Miljanovic, Maja Cupic. Hepatitis B Surface Antigen Isoforms: Their Clinical Implications, Utilisation in Diagnosis, Prevention and New Antiviral StrategiesPathogens 2024; 13(1): 46 doi: 10.3390/pathogens13010046
24
Sara Delghandi, Ramin Raoufinia, Sahar Shahtahmasbi, Zahra Meshkat, Hamed Gouklani, Aida Gholoobi. An overview of occult hepatitis B infection (OBI) with emphasis on HBV vaccinationHeliyon 2024; 10(17): e37097 doi: 10.1016/j.heliyon.2024.e37097
25
Yu-Min Choi, Junghwa Jang, Dong Hyun Kim, Ziyun Kim, Eunseo Kim, Won Hyeok Choe, Bum-Joon Kim. PreS1 deletions in genotype C HBV leads to severe hepatic inflammation and hepatocarcinogenesis via the IRE1-JNK axisJHEP Reports 2025; 7(3): 101274 doi: 10.1016/j.jhepr.2024.101274
26
Yuanyuan Liu, Vaishnavi Veeraraghavan, Monica Pinkerton, Jianjun Fu, Mark W. Douglas, Jacob George, Thomas Tu. Viral Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma Occurrence and RecurrenceFrontiers in Microbiology 2021; 12 doi: 10.3389/fmicb.2021.665201
27
Wei Teng, Ting-Tsung Chang, Chien-Wei Su, Jun-Hao Xu, Chiu-Chi Hsu, Yu-Cheng Chang, Wen-Chun Liu, Yu-Wei Chiou, Yu-Chuan Chang, Yuh-Jin Liang, Jaw-Ching Wu. The impact of single-nucleotide variants of hepatitis B virus and antiviral on liver cancer in gray zone patientsJournal of Biomedical Science 2025; 32(1) doi: 10.1186/s12929-025-01195-x
28
Tárcio Peixoto Roca, Livia Melo Villar, Felipe Souza Nogueira Lima, Mariana Pinheiro Alves Vasconcelos, Lourdes Maria Pinheiro Borzacov, Eugênia de Castro e Silva, Bárbara Vieira do Lago, Mayara Torquato Lima da Silva, Luan Felipo Botelho Souza, Juan Miguel Villalobos Salcedo, Alcione de Oliveira dos Santos, Deusilene Souza Vieira. Genomic Variability of Hepatitis B Virus Circulating in Brazilian Western AmazonViruses 2022; 14(10): 2100 doi: 10.3390/v14102100
29
Eleanor A. Powell, Yi‐Wei Tang. ClinMicroNow2023; : 1 doi: 10.1002/9781683670438.mcm0112
30
Xingxin Zhang, Chenjian Gu, Qian Wei, Yirong Cao, Weimin She, Hong Shi, Youhua Xie, Jinsheng Guo. Pre-S1 Mutations as Indicated by Serum Pre-S1 Antigen Negative is Associated with an Increased Risk of Hepatocellular Carcinoma in Chronic Hepatitis B PatientsJournal of Hepatocellular Carcinoma 2023; : 599 doi: 10.2147/JHC.S373333
31
Tingxi Yan, Yusheng Zhang, Huifang Zhou, Ning Jiang, Xiaotong Wang, Wei Yan, Jianhua Yin. Surface Gene Mutations of Hepatitis B Virus and Related Pathogenic Mechanisms: A Narrative ReviewViruses 2025; 17(7): 974 doi: 10.3390/v17070974
32
Tengyue Hu, Jiayi Wang, Weixiu Li, Miao Liu, Ning Han, Man Yuan, Lingyao Du, Hong Tang. Endoplasmic Reticulum Stress in Hepatitis B Virus and Hepatitis C Virus InfectionViruses 2022; 14(12): 2630 doi: 10.3390/v14122630
33
Damien Cohen, Sumantra Ghosh, Yusuke Shimakawa, Njie Ramou, Pierre Simon Garcia, Anaëlle Dubois, Clément Guillot, Nora Kakwata-Nkor Deluce, Valentin Tilloy, Geoffroy Durand, Catherine Voegele, Gibril Ndow, Umberto d'Alessandro, Céline Brochier-Armanet, Sophie Alain, Florence Le Calvez-Kelm, Janet Hall, Fabien Zoulim, Maimuna Mendy, Mark Thursz, Maud Lemoine, Isabelle Chemin. Hepatitis B virus preS2Δ38–55 variants: A newly identified risk factor for hepatocellular carcinomaJHEP Reports 2020; 2(5): 100144 doi: 10.1016/j.jhepr.2020.100144
34
Yan Guo, Yu Lan, Yuanyuan Jing, Bin Cai, Hanshi Gong, Yixin Zhang, Yong Duan, Era Upadhyay. The Investigation of HBV Pre-S/S Gene Mutations in Occult HBV Infected Blood Donors with anti-HBs PositiveCanadian Journal of Infectious Diseases and Medical Microbiology 2022; 2022: 1 doi: 10.1155/2022/1874435
35
Shalini Sakthivel, L. Preethi, Prudhvi Lal Bhukya. Emerging Human Viral Diseases, Volume II2024; : 509 doi: 10.1007/978-981-97-4480-0_19
36
Lung-Yi Mak, Danny Ka-Ho Wong, Teresa Pollicino, Giovanni Raimondo, F. Blaine Hollinger, Man-Fung Yuen. Occult hepatitis B infection and hepatocellular carcinoma: Epidemiology, virology, hepatocarcinogenesis and clinical significanceJournal of Hepatology 2020; 73(4): 952 doi: 10.1016/j.jhep.2020.05.042
37
Eleanor A. Powell, Yi‐Wei Tang. ClinMicroNow2023; : 1 doi: 10.1002/9781683674849.mcm0112
38
Serkan Aydemir, Mustafa Taner Yildirmak, Murat Sayan, Süheyla Atak, Mehmet Kucuk. A chronic hepatitis B patient infected with HBsAg diagnostic-escape strain in the presence of anti-HBs positivityRevista Romana de Medicina de Laborator 2019; 27(4): 421 doi: 10.2478/rrlm-2019-0038
39
Mohammad Hossein Ahmadi, Zohreh Sharifi, Ali Ghasemi, Sadegh Abbasian. Occult hepatitis B in Iranian blood donors, an overview of the challenges: A narrative reviewHealth Science Reports 2023; 6(8) doi: 10.1002/hsr2.1466
40
Wei Wang, Yi Shu, Han Bao, Wenliang Zhao, Weihua Wang, Qin Wang, Xiaoying Lei, Daxiang Cui, Zhen Yan. Genotypes and Hot Spot Mutations of Hepatitis B Virus in Northwest Chinese Population and Its Correlation with Diseases ProgressionBioMed Research International 2019; 2019: 1 doi: 10.1155/2019/3890962
41
Linzhu Yi, Jiaxin Wu, Zhiqing Yang, Yandi Li, Jia Lian, Tian Yao, Shuying Feng, Bo Wang, Yongliang Feng, Suping Wang. Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmissionRevista do Instituto de Medicina Tropical de São Paulo 2023; 65 doi: 10.1590/s1678-9946202365046
42
Qing Xiao, Yi Liu, Tingting Li, Chaoyu Wang, Sanxiu He, Liuyue Zhai, Zailin Yang, Xiaomei Zhang, Yongzhong Wu, Yao Liu. Viral oncogenesis in cancer: from mechanisms to therapeuticsSignal Transduction and Targeted Therapy 2025; 10(1) doi: 10.1038/s41392-025-02197-9
43
Hong-Yuan Hsu, Huey-Ling Chen, Cheng-Lun Chiang, Ming-Wei Lai, Shu-Chi Mu, Wan-Hsin Wen, Shao-Wen Cheng, Jen-Jan Hu, Kai-Chi Chang, Chien-Nan Lee, Chun-Jen Liu, Jia-Feng Wu, Yen-Hsuan Ni, Mei-Hwei Chang, MK Shyu, HL Hwa, YN Su, JC Shih, KH Chao, YC Chiu, TH Su, Zhao Lu-Lu, CK Yang, YK Chang, KH Chen, HH Lin, SM Chen, CC Lin, PY Lin, WR Yang, YH Lin, HJ Chen, HS Pan, BH Lau, CL Lee, PJ Cheng, YL Chang, HY Chiueh, TH Wang, JJ Hsu, LM Lo, CL Hsieh, SW Cheng, MS Tsai, BQ She, FS Peng, YC Lin, CP Chen, JP Huang, CY Yeung. Characterization of Hepatitis B Virus in Tenofovir-Treated and Untreated Chronically Infected Mothers and Their Immunoprophylaxis Failure InfantsClinical Infectious Diseases 2023; 76(3): e783 doi: 10.1093/cid/ciac539
44
Nguyen Thi Cam Huong, Nguyen Quang Trung, Bac An Luong, Duong Bich Tram, Hoang Anh Vu, Hoang Huu Bui, Hoa Pham Thi Le, Hussein H. Aly. Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patientsPLOS ONE 2022; 17(4): e0266134 doi: 10.1371/journal.pone.0266134
45
Shreyasi Athalye, Naveen Khargekar, Priyanka Panale, Shailesh Shinde, Aruna Shankarkumar, Anindita Banerjee. Molecular Insights Into the S Gene of Hepatitis B Virus: Analysis Among Household Contacts and Clinical Implications of MutationsJournal of Viral Hepatitis 2026; 33(1) doi: 10.1111/jvh.70124
46
Daniela Bender, Eberhard Hildt. Effect of Hepatitis Viruses on the Nrf2/Keap1-Signaling Pathway and Its Impact on Viral Replication and PathogenesisInternational Journal of Molecular Sciences 2019; 20(18): 4659 doi: 10.3390/ijms20184659
47
Huizhen Sun, Le Chang, Ying Yan, Lunan Wang. Hepatitis B virus pre‐S region: Clinical implications and applicationsReviews in Medical Virology 2021; 31(4) doi: 10.1002/rmv.2201
48
Bi-Xia Huang, Yan Liu, Zhen-Ping Fan, Lan-Lan Si, Rong-Juan Chen, Jun Wang, Dan Luo, Fu-Sheng Wang, Dong-Ping Xu, Xin-Guang Liu. Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutationsWorld Journal of Gastroenterology 2020; 26(35): 5314-5327 doi: 10.3748/wjg.v26.i35.5314
49
Yong Lin, Zhenyu Zhao, Ailong Huang, Mengji Lu. Interplay between Cellular Autophagy and Hepatitis B Virus Replication: A Systematic ReviewCells 2020; 9(9): 2101 doi: 10.3390/cells9092101