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For: Duan LF, Xu XF, Zhu LJ, Liu F, Zhang XQ, Wu N, Fan JW, Xin JQ, Zhang H. Dachaihu decoction ameliorates pancreatic fibrosis by inhibiting macrophage infiltration in chronic pancreatitis. World J Gastroenterol 2017; 23(40): 7242-7252 [PMID: 29142471 DOI: 10.3748/wjg.v23.i40.7242]
URL: https://www.wjgnet.com/1007-9327/full/v23/i40/7242.htm
Number Citing Articles
1
Fenglin Hu, Ni Lou, Juying Jiao, Fangyue Guo, Hong Xiang, Dong Shang. Macrophages in pancreatitis: Mechanisms and therapeutic potentialBiomedicine & Pharmacotherapy 2020; 131 doi: 10.1016/j.biopha.2020.110693
2
Yu Zhang, Wen-Qing Zhang, Xin-Yuan Liu, Qi Zhang, Tao Mao, Xiao-Yu Li. Immune cells and immune cell-targeted therapy in chronic pancreatitisFrontiers in Oncology 2023; 13 doi: 10.3389/fonc.2023.1151103
3
Xin-rui Xing, Hong-cong Qiu, Ying Liu, Tian Tang, Yuan-yuan Zhai, Yuan Tian, Feng-xia Qin, Zun-jian Zhang, Pei Zhang, Feng-guo Xu. Lonicerin from Dachaihu decoction ameliorates liver steatosis and fibrosis in MASH by inhibiting LY6DJournal of Ethnopharmacology 2026; 371 doi: 10.1016/j.jep.2026.122097
4
Shan Guo, Qi Zhang, Yingjie Guo, Xiaoyan Yin, Peng Zhang, Tao Mao, Zibin Tian, Xiaoyu Li. The role and therapeutic targeting of the CCL2/CCR2 signaling axis in inflammatory and fibrotic diseasesFrontiers in Immunology 2025; 15 doi: 10.3389/fimmu.2024.1497026
5
Zhen Yang, Xingyu Kao, Lin Zhang, Na Huang, Yi Wang, Jingli Chen, Mingfeng He, Qi Tang, Zhangrong Liang. Dachaihu decoction alleviates septic liver injury by modulating the intestinal barrier dysfunction and suppressing the NF-κB/NLRP3/Caspase-1 signaling pathwayChinese Medicine 2026; 21(1) doi: 10.1186/s13020-026-01420-1
6
Yan Zhang, Sujie Li, Xiujiang Zhang, Pei Wang, Zhe Meng, Yuming Pang, Wei Li. Study on the Mechanism of Dachaihu Decoction in the Treatment of Acute Pancreatitis Based on Artificial Intelligence Combined with in vivo ExperimentsCombinatorial Chemistry & High Throughput Screening 2023; 26(13) doi: 10.2174/1386207326666230202140740
7
Jae-Hoon Jeong, Shin-Hyung Park. Anti-migration Effects of the Daesiho-tang (Da Chai Hu-Tang) Water Extract in Cancer Cells by Regulating Macrophage PolarizationJournal of Physiology & Pathology in Korean Medicine 2024; 38(1) doi: 10.15188/kjopp.2024.02.38.1.32
8
Joonseong Jang, Younghyun Park, Michung Yoon. Effects of Gyeongshingangjeehwan 18 on Pancreatic Fibroinflammation in High-Fat Diet-Fed Obese C57BL/6J MiceBiomedical Science Letters 2018; 24(4) doi: 10.15616/BSL.2018.24.4.341
9
Jiaqi Cui, Di Wu, Huimin Zhou, Haiyan Chen, Zhixia Dong, Jun Yang. Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative reviewJournal of Pancreatology 2022; 5(4) doi: 10.1097/JP9.0000000000000111
10
Chang Liu, Shuang Li, Qingkai Zhang, Fangyue Guo, Mengying Tong, Maria Francesca Ysabelle M. Martinez, Heather H. Wang, Yutong Zhao, Dong Shang. Emerging Role of Chinese Herbal Medicines in the Treatment of Pancreatic FibrosisThe American Journal of Chinese Medicine 2019; 47(04) doi: 10.1142/S0192415X1950037X
11
Nan Wu, Xiao‐Fan Xu, Jia‐Qi Xin, Jian‐Wei Fan, Yuan‐Yuan Wei, Qing‐Xia Peng, Li‐Fang Duan, Wei Wang, Hong Zhang. The effects of nuclear factor‐kappa B in pancreatic stellate cells on inflammation and fibrosis of chronic pancreatitisJournal of Cellular and Molecular Medicine 2021; 25(4) doi: 10.1111/jcmm.16213
12
O. Kalmukova, K. Chumak, O. Voronina, M. Dzerzhynsky. Morpho-functional state of rat pancreas under melatonin administration during obesity development: chronotherapeutic approachBulletin of Taras Shevchenko National University of Kyiv. Series: Biology 2020; 80(1) doi: 10.17721/1728_2748.2020.80.50-56
13
Guixian Zhang, Xiumei Zhao, Jun Cai, Sainan Li, Xijing Li, Wenchang Li, Pengcheng Shi, Dawei Liu, Duo Zheng, Ting Zhang, Renrui Feng, Hongbin Liu. XCHT alleviates the pancreatic fibrosis via VDR/NLRP3 signaling pathway in a mouse model of CPJournal of Ethnopharmacology 2023; 300 doi: 10.1016/j.jep.2022.115689
14
Xiao-Fan Xu, Jian-Wei Fan, Jia-Qi Xin, Nan Wu, He Gao, Li-Fang Duan, Wen-Bin Zou, Hong Zhang, Zhao-Shen Li. Aspirin Ameliorates Pancreatic Inflammation and Fibrosis by Inhibiting COX-2 Expression in Experimental Chronic PancreatitisJournal of Inflammation Research 2022;  doi: 10.2147/JIR.S375383
15
Yangping Shentu, Shuqing Ma, Simin Ye, Yaozhe Ying, Luhui Wang, Yun Zhu, YunTing Wang, Nan Jiang, Zongyuan Zhao, Chenfei Zheng, Chaosheng Chen, Yongheng Bai, Ying Zhou. Interleukin‐6 induces cognitive impairment via toll‐like receptor 4 (TLR4)‐mediated neuroinflammation and neurodegeneration in mice with chronic kidney diseaseNeuroprotection 2024; 2(3) doi: 10.1002/nep3.54
16
Chengning Yang, Yuqing Wang, Lijian Liu, Zuomei Luo, Nan Chen, Zhu Liu, Liqun Li, Guangwen Chen. The causal relationship between 91 inflammatory cytokines and chronic pancreatitis, and the mediating role of 1400 metabolitesMedicine 2025; 104(38) doi: 10.1097/MD.0000000000043880
17
Xue Jiang, Ya-Wen Zheng, Shihui Bao, Hailin Zhang, Ruijie Chen, Qing Yao, Longfa Kou. Drug discovery and formulation development for acute pancreatitisDrug Delivery 2020; 27(1) doi: 10.1080/10717544.2020.1840665
18
Hong Xiang, Hao Yu, Qi Zhou, Yu Wu, Jiaqi Ren, Zirui Zhao, Xufeng Tao, Deshi Dong. Macrophages: A rising star in immunotherapy for chronic pancreatitisPharmacological Research 2022; 185 doi: 10.1016/j.phrs.2022.106508
19
Zhangli Yan, Xin Chen, Xin Cao, Jianwei Fan, Lifang Duan, Nan Wu, Jiaqi Xin, Xu Li, Xiaofan Xu, Hong Zhang. The Effects of Da-Chai-Hu Decoction Alleviating Pancreatic Exocrine Dysfunction by Inhibiting Endoplasmic Reticulum Stress of Acinar Cell in Mice with Chronic PancreatitisJournal of Inflammation Research 2025;  doi: 10.2147/JIR.S555252
20
Zhen Qin, Xiaohong Sun, Jingmin Zeng, Guorong Li, Haixia Wang, Shujun Chen, Shiyun Tan, Lin An, Caiyan Wang, Liming Wang, Jinping Wang, Xiaowen Ma, Zhongxiang Zhao, Xiaojuan Chao, Zhongqiu Liu, Shaogui Wang. Wogonin, a bioactive flavonoid from Scutellaria baicalensis, alleviates alcoholic pancreatitis via AMPK-mediated TFEB activationJournal of Advanced Research 2025;  doi: 10.1016/j.jare.2025.11.006
21
Guo-Wang Yao, Cai-Xia Li, Yu-Xing Fan, Yu-Zhen Zhuo, Shu-Kun Zhang, Li-Hua Cui. Chaihu Guizhi Ganjiang Decoction ameliorates chronic pancreatitis by modulating the SK1/S1P signaling pathwayJournal of Natural Medicines 2025; 79(3) doi: 10.1007/s11418-025-01901-x
22
Enrique Verdú, Judit Homs, Pere Boadas-Vaello. Physiological Changes and Pathological Pain Associated with Sedentary Lifestyle-Induced Body Systems Fat Accumulation and Their Modulation by Physical ExerciseInternational Journal of Environmental Research and Public Health 2021; 18(24) doi: 10.3390/ijerph182413333
23
Shihao Xu, Xi Qiao, Peike Peng, Ziyi Zhu, Yaoting Li, Mengyuan Yu, Long Chen, Yin Cai, Jin Xu, Xinwei Shi, Christopher G. Proud, Jianling Xie, Kaikai Shen. Da-Chai-Hu-Tang Protects From Acute Intrahepatic Cholestasis by Inhibiting Hepatic Inflammation and Bile Accumulation via Activation of PPARαFrontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.847483
24
Igor E. Khatkov, Dmitry S. Bordin, Konstantin A. Lesko, Elena A. Dubtsova, Nikolay S. Karnaukhov, Maria A. Kiriukova, Nadezhda V. Makarenko, Alexey S. Dorofeev, Irina V. Savina, Diana A. Salimgereeva, Elena I. Shurygina, Ludmila V. Vinokurova. Contrast-Enhanced Computed Tomography and Laboratory Parameters as Non-Invasive Diagnostic Markers of Pancreatic FibrosisDiagnostics 2023; 13(14) doi: 10.3390/diagnostics13142435
25
Jianwei Fan, Lifang Duan, Nan Wu, Xiaofan Xu, Jiaqi Xin, Shengnan Jiang, Cheng Zhang, Hong Zhang. Baicalin Ameliorates Pancreatic Fibrosis by Inhibiting the Activation of Pancreatic Stellate Cells in Mice with Chronic PancreatitisFrontiers in Pharmacology 2021; 11 doi: 10.3389/fphar.2020.607133
26
Amir Khenchil, Hocine Rechreche, Arbia Abbes, Elisa Pettineo, Chiara Dianzani, Moufida Bensam, Widad Sobhi, Stefania Pizzimenti. Methanol Extract from Ranunculus repens L. Down-Regulated Galectins 4 and 9, and Mitigated Chronic Pancreatitis in an Experimental Rat ModelAntioxidants 2025; 14(12) doi: 10.3390/antiox14121436
27
Qiang Chen, Xinru Chen, Yuqing Zhu, Xiali Yu. A relatively rare traditional Chinese medicine pattern of primary Sjögren syndrome: A case reportMedicine 2024; 103(15) doi: 10.1097/MD.0000000000037744
28
Jianbin Xiong, Jian Song, Xing Jiang, Zhuanzhuan Huang, Yijie Zhang. Prkcq in ILC2 cells-enhanced the amounts of tissue-resident macrophages promotes pancreatic fibrosis in chronic pancreatitisArchives of Biochemistry and Biophysics 2025; 772 doi: 10.1016/j.abb.2025.110559
29
Xiao-Fan Xu, Fang Liu, Jia-Qi Xin, Jian-Wei Fan, Nan Wu, Lin-Jia Zhu, Li-Fang Duan, Yong-Yu Li, Hong Zhang. Respective roles of the mitogen-activated protein kinase (MAPK) family members in pancreatic stellate cell activation induced by transforming growth factor-β1 (TGF-β1)Biochemical and Biophysical Research Communications 2018; 501(2) doi: 10.1016/j.bbrc.2018.04.176
30
Na Huang, Yu Wei, Meng Liu, Zhen Yang, Kang Yuan, Jingli Chen, Zhixin Wu, Fanghao Zheng, Kaijun Lei, Mingfeng He. Dachaihu decoction ameliorates septic intestinal injury via modulating the gut microbiota and glutathione metabolism as revealed by multi-omicsJournal of Ethnopharmacology 2023; 312 doi: 10.1016/j.jep.2023.116505
31
Dong Mu, Beijin Chen, Xiaoli Liu, Shumei Zheng, Yong Zhang, Hua Ni, Dejiang Zhou. Exploring the potential mechanisms of Da ChaiHu decoction against pancreatic cancer based on network pharmacology prediction and molecular docking approachNaunyn-Schmiedeberg's Archives of Pharmacology 2025; 398(10) doi: 10.1007/s00210-025-04107-w
32
Yunfei Dai, Xi Guan, Fangyue Guo, Xin Kong, Shuqi Ji, Dong Shang, Changchuan Bai, Qingkai Zhang, Liang Zhao. Botanical drugs and their natural compounds: a neglected treasury for inhibiting the carcinogenesis of pancreatic ductal adenocarcinomaPharmaceutical Biology 2024; 62(1) doi: 10.1080/13880209.2024.2421759
33
S. Madesh, Mukil Srivasan, S.P. Ramya Ranjan Nayak, Santhanam Sanjai Dharshan, Marapatla Shiny, Girija Sastry Vedula, Bader O. Almutairi, Ilavenil Soundharrajan, Kathiravan Muthu Kumaradoss, Jesu Arockiaraj. Therapeutic potential of alginate-stabilized silver nanoparticles encapsulating nitrogen-containing heterocyclic derivative mitigates inflammation and fibrosis in L-arginine induced in vivo zebrafish model of chronic pancreatitisInternational Journal of Biological Macromolecules 2026; 365 doi: 10.1016/j.ijbiomac.2026.152404
34
Ruolei Wang, Fengjing Jia, Zhenguo Zhao, Liqing Du, Lianheng Lu, Dongkui Xu, Feng He. Dachaihu decoction inhibits hypernutrition-induced liver metastasis from colorectal cancer by maintaining the gut vascular barrierCancer Pathogenesis and Therapy 2023; 1(2) doi: 10.1016/j.cpt.2023.02.003
35
Zhen Yang, Xingyu Kao, Lin Zhang, Na Huang, Jingli Chen, Mingfeng He. Exploring the Anti-PANoptosis Mechanism of Dachaihu Decoction Against Sepsis-Induced Acute Lung Injury: Network Pharmacology, Bioinformatics, and Experimental ValidationDrug Design, Development and Therapy 2025;  doi: 10.2147/DDDT.S495225
36
Sapana Bansod, Amit Khurana, Chandraiah Godugu. Cerulein-induced chronic pancreatitis in Swiss albino mice: An improved short-term model for pharmacological screeningJournal of Pharmacological and Toxicological Methods 2019; 96 doi: 10.1016/j.vascn.2019.01.002
37
Muyun Liu, Lizhe Ma, Wei An, Yaying Yang, Juncen Liu, Hui Jiang, Jihang Yuan, Xiaoru Sun, Jingyi Zhu, Maoyun Yan, Luowei Wang, Zhaoshen Li, Zhuan Liao, Chang Sun. Heterozygous Spink1 c.194+2T>C mutation promotes chronic pancreatitis after acute attack in micePancreatology 2024; 24(5) doi: 10.1016/j.pan.2024.05.514
38
Kexin Gan, Yonghong Hu, Wei Liu, Jiewen Shi, Sen Yang, Jinxin Huang, Xuan Wang, Fu Li. Therapeutic potential of traditional Chinese medicine in pancreatic fibrosis: mechanisms of TCM formulas and active ingredientsFrontiers in Pharmacology 2025; 16 doi: 10.3389/fphar.2025.1609569
39
Xu Li, Zhangli Yan, Xin Cao, Xin Chen, Zheng Guan, Shangan Tang, Jianwei Fan, Lifang Duan, Xiaofan Xu, Hong Zhang. Dachaihu Decoction alleviates chronic pancreatitis by regulating MAPK signaling pathway: Insights from network pharmacology and experimental validationJournal of Ethnopharmacology 2025; 337 doi: 10.1016/j.jep.2024.118833
40
Xiao-ju Su, Yan Chen, Qi-chen Zhang, Xiao-bo Peng, Ya-ping Liu, Lei Wang, Yi-qi Du. Exosomes Derived From Cerulein-Stimulated Pancreatic Acinar Cells Mediate Peritoneal Macrophage M1 Polarization and Pyroptosis via an miR-24-3p/MARCH3/NLRP3 Axis in Acute PancreatitisPancreas 2024; 53(8) doi: 10.1097/MPA.0000000000002351