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For: Jeon TJ, Park JY. Clinical significance of the neutrophil-lymphocyte ratio as an early predictive marker for adverse outcomes in patients with acute pancreatitis. World J Gastroenterol 2017; 23(21): 3883-3889 [PMID: 28638228 DOI: 10.3748/wjg.v23.i21.3883]
URL: https://www.wjgnet.com/1007-9327/full/v23/i21/3883.htm
Number Citing Articles
1
Maninder Kaur, Karamvir Chandel, Pavan Reddy, Pankaj Gupta, Jayanta Samanta, Harshal Mandavdhare, Vishal Sharma, Harjeet Singh, Shano Naseem, Saroj K. Sinha, Vikas Gupta, Thakur D. Yadav, Usha Dutta, Rakesh Kochhar, Manavjit S. Sandhu. Neutrophil-lymphocyte Ratio Predicts Clinical Response to Percutaneous Transhepatic Biliary Drainage in Acute CholangitisJournal of Clinical and Experimental Hepatology 2023; 13(3): 390 doi: 10.1016/j.jceh.2023.01.002
2
Jurijus Makevičius, Albertas Čekauskas, Arūnas Želvys, Albertas Ulys, Feliksas Jankevičius, Marius Miglinas. Evaluation of Renal Function after Partial Nephrectomy and Detection of Clinically Significant Acute Kidney InjuryMedicina 2022; 58(5): 667 doi: 10.3390/medicina58050667
3
Sarah J. Neal Webb, Steven J. Schapiro, Chet C. Sherwood, Mary Ann Raghanti, William D. Hopkins, Santiago Partida-Sanchez. Neutrophil to Lymphocyte Ratio (NLR) in captive chimpanzees (Pan troglodytes): The effects of sex, age, and rearingPLOS ONE 2020; 15(12): e0244092 doi: 10.1371/journal.pone.0244092
4
Yang Li, Zhouping Zou, Yunlu Zhang, Bowen Zhu, Yichun Ning, Bo Shen, Chunsheng Wang, Zhe Luo, Jiarui Xu, Xiaoqiang Ding. Dynamics in perioperative neutrophil-to-lymphocyte*platelet ratio as a predictor of early acute kidney injury following cardiovascular surgeryRenal Failure 2021; 43(1): 1012 doi: 10.1080/0886022X.2021.1937220
5
Robert M. O'Connell, Michael R. Boland, Jeremiah O'Driscoll, Abdelmonim Salih, Mayilone Arumugasamy, Thomas N. Walsh, Michael J. Allen, David J. Beddy. Red cell distribution width and neutrophil to lymphocyte ratio as predictors of outcomes in acute pancreatitis: A retrospective cohort studyInternational Journal of Surgery 2018; 55: 124 doi: 10.1016/j.ijsu.2018.05.028
6
Ronghe Zhu, Cuie Chen, Qiu Wang, Xixi Zhang, Chaosheng Lu, Yuanyuan Sun. Routine blood parameters are helpful for early identification of influenza infection in childrenBMC Infectious Diseases 2020; 20(1) doi: 10.1186/s12879-020-05584-5
7
Li Huang, Congying Chen, Lijuan Yang, Rong Wan, Guoyong Hu. Neutrophil‐to‐lymphocyte ratio can specifically predict the severity of hypertriglyceridemia‐induced acute pancreatitis compared with white blood cellJournal of Clinical Laboratory Analysis 2019; 33(4) doi: 10.1002/jcla.22839
8
Cevher Akarsu, Mehmet Karabulut, Husnu Aydin, Nuri Alper Sahbaz, Ahmet Cem Dural, Duygu Yegul, Kivanc Derya Peker, Sina Ferahman, Sezer Bulut, Turgut Dönmez, Sinan Asar, Kadriye Kart Yasar, Gokhan Tolga Adas. Association between Acute Pancreatitis and COVID-19: Could Pancreatitis Be the Missing Piece of the Puzzle about Increased Mortality Rates?Journal of Investigative Surgery 2022; 35(1): 119 doi: 10.1080/08941939.2020.1833263
9
Utkarsh Pradeep, Anjalee Chiwhane, Sourya Acharya, Sunil Kumar, Varun Daiya, Paschyanti R Kasat, Aman Gupta, Gautam N Bedi. The Role of Neutrophil-to-Lymphocyte Ratio in Predicting Outcomes of Acute Organophosphorus Poisoning: A Comprehensive ReviewCureus 2024;  doi: 10.7759/cureus.60854
10
T. V. Formanchuk, V. O. Shaprinskiy, O. M. Lopushanskiy. NEUTROPHIL-LYMPHOCYTE RATIO AS AN EARLY PROGNOSTIC PREDICTOR OF THE COURSE OF ACUTE PANCREATITISKharkiv Surgical School 2022; (2): 12 doi: 10.37699/2308-7005.2.2022.02
11
Tetiana Formanchuk, Hryhoriy Lapshyn, Mariya Pokidko, Andrii Formanchuk, Igor Vovchuk. The relationship between neutrophil-lymphocyte ratio and clinal laboratory data in acute pancreatitisActa Facultatis Medicae Naissensis 2022; 39(4): 451 doi: 10.5937/afmnai39-34988
12
Patricia Mihaela Radulescu, Dragos Virgil Davitoiu, Vlad Dumitru Baleanu, Vlad Padureanu, Dumitru Sandu Ramboiu, Marin Valeriu Surlin, Tudor Constantin Bratiloveanu, Eugen Florin Georgescu, Costin Teodor Streba, Razvan Mercut, Elena Irina Caluianu, Emil Tiberius Trasca, Dumitru Radulescu. Has COVID-19 Modified the Weight of Known Systemic Inflammation Indexes and the New Ones (MCVL and IIC) in the Assessment as Predictive Factors of Complications and Mortality in Acute Pancreatitis?Diagnostics 2022; 12(12): 3118 doi: 10.3390/diagnostics12123118
13
政浩 李. Research Progress on Predicting the Severity and Prognosis of Acute PancreatitisAdvances in Clinical Medicine 2024; 14(11): 1011 doi: 10.12677/acm.2024.14112977
14
Archit Garg, Dipankar Naskar, Nikhil Gupta, Raghav Yelamanchi, Arun Kumar Gupta. Comparison of Red Cell Distribution Width and Neutrophil Lymphocyte Ratio with APACHE II Score in Predicting Severity of Acute PancreatitisIndian Journal of Surgery 2022; 84(S2): 492 doi: 10.1007/s12262-022-03345-z
15
Zeynep Bıyık. Akut pankreatitli hastalarda akut böbrek hasarını öngörmedeki nötrofil lenfosit oranının rolüAkademik Gastroenteroloji Dergisi 2019; 18(1): 16 doi: 10.17941/agd.548747
16
Jia-Jin Chen, George Kuo, Pei-Chun Fan, Tao-Han Lee, Chieh-Li Yen, Cheng-Chia Lee, Ya-Chung Tian, Chih-Hsiang Chang. Neutrophil-to-lymphocyte ratio is a marker for acute kidney injury progression and mortality in critically ill populations: a population-based, multi-institutional studyJournal of Nephrology 2022; 35(3): 911 doi: 10.1007/s40620-021-01162-3
17
Gaoli Liu, Jing Tao, Zhongchao zhu, Weixing Wang. The early prognostic value of inflammatory markers in patients with acute pancreatitisClinics and Research in Hepatology and Gastroenterology 2019; 43(3): 330 doi: 10.1016/j.clinre.2018.11.002
18
William Khoury, Judah Glogauer, Howard C Tenenbaum, Michael Glogauer. Oral inflammatory load: Neutrophils as oral health biomarkersJournal of Periodontal Research 2020; 55(5): 594 doi: 10.1111/jre.12758
19
Sang Hoon Lee, Tae Yoon Lee, Young Koog Cheon. The Neutrophil-Lymphocyte Ratio as an Early Predictive Marker of the Severity of Post-Endoscopic Retrograde Cholangiopancreatography PancreatitisMedicina 2021; 58(1): 13 doi: 10.3390/medicina58010013
20
Noman A Khan, Syed Jawad Haider Kazmi, Muhammad Sohaib Asghar, Manjeet Singh, Shahid Iqbal, Rumael Jawed, Lal Muhammad, Tooba Ahmed Kirmani, Salman Ahmed Khan, Iqra Anees Rajput. Hematological Indices Predicting the Severity of Acute Pancreatitis Presenting to the Emergency Department: A Retrospective AnalysisCureus 2021;  doi: 10.7759/cureus.16752
21
Rezan Karaali, Firdes Topal. Evaluating the effect of SARS-Cov-2 infection on prognosis and mortality in patients with acute pancreatitisThe American Journal of Emergency Medicine 2021; 49: 378 doi: 10.1016/j.ajem.2021.06.045
22
Naciye S Gezer, Göksel Bengi, Agah Baran, Pakize E Erkmen, Ömer S Topalak, Canan Altay, Oğuz Dicle. Comparison of radiological scoring systems, clinical scores, neutrophil-lymphocyte ratio and serum C-reactive protein level for severity and mortality in acute pancreatitisRevista da Associação Médica Brasileira 2020; 66(6): 762 doi: 10.1590/1806-9282.66.6.762
23
Bahri ABAYLI, Genco GENCDAL. Investigating Possible Risk Factors and Prognostic Markers for Post-Endoscopic Retrograde Cholangiopancreatography PancreatitisEndoskopi Gastrointestinal 2020; 28(Sayı: 3): 77 doi: 10.17940/endoskopi.753336
24
Jie Xue, Xiao-Guang Zhang, Hua-Yu Jiang, Xian-Kai Cui, Dong Zhang, Zhi-Wen Yao, Yun-Hua Yue. An increase in neutrophil-to-lymphocyte ratio predicts poor functional outcomes in older patients with acute ischemic stroke: a retrospective studyJournal of Integrative Neuroscience 2021; 20(2) doi: 10.31083/j.jin2002040
25
Murat Alpua, Bahar Say, Ilknur Yardimci, Ufuk Ergün, Ucler Kisa, Ozlem Doğan Ceylan. Response to Letter to the Editor: “First Admission Neutrophil–Lymphocyte Ratio May Indicate Acute Prognosis of Ischemic Stroke”Rambam Maimonides Medical Journal 2021; 12(4): e0036 doi: 10.5041/RMMJ.10457
26
Georgiana Cătălina Crișu, Valeriu Atanasiu, Flavius Ștefan Marin, Vasile Daniel Balaban, Laura Găman, Irina Stoian, Mariana Jinga. Neutrophil to Lymphocyte Ratio and Thrombocyte to Lymphocyte Ratio, New Biochemical Parameters in Acute PancreatitisInternal Medicine 2020; 17(1): 21 doi: 10.2478/inmed-2020-0098
27
Tudorel Mihoc, Cristi Tarta, Ciprian Duta, Raluca Lupusoru, Greta Dancu, Monica Anca Oprescu-Macovei, Amadeus Dobrescu, Fulger Lazar. Monitoring Approach of Fatality Risk Factors for Patients with Severe Acute Pancreatitis Admitted to the Intensive Care Unit. A Retrospective, Monocentric StudyDiagnostics 2021; 11(11): 2013 doi: 10.3390/diagnostics11112013
28
Xinrui Jin, Zixuan Ding, Tao Li, Jie Xiong, Gang Tian, Jinbo Liu. Comparison of MPL-ANN and PLS-DA models for predicting the severity of patients with acute pancreatitis: An exploratory studyThe American Journal of Emergency Medicine 2021; 44: 85 doi: 10.1016/j.ajem.2021.01.044
29
Dessy Iriana, Ani Kartini, Yuyun Widaningsih, Agus Alim Abdullah. Neutrophil-Lymphocyte Ratio and Procalcitonin as Predictors of the Severity of Acute PancreatitisINDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 2021; 28(1): 66 doi: 10.24293/ijcpml.v28i1.1699
30
Miriam Larouche, Diane Brisson, Marie-Claude Morissette, Daniel Gaudet. Post-prandial analysis of fluctuations in the platelet count and platelet function in patients with the familial chylomicronemia syndromeOrphanet Journal of Rare Diseases 2023; 18(1) doi: 10.1186/s13023-023-02743-0
31
Yun Liu, Jun Ni, Yali Xiong, Chao Wu, Fei He. Neutrophil-to-lymphocyte ratio is associated with 28-day mortality in patients with severe fever with thrombocytopenia syndromeBMC Infectious Diseases 2022; 22(1) doi: 10.1186/s12879-022-07206-8
32
Tansu Aykan, Adem Az, Özgür Söğüt, Tarık Akdemir, Tuba Selçuk Can. The Prognostic Role of Systemic Inflammatory Parameters and Severity Scores in Patients with Acute PancreatitisGlobal Emergency and Critical Care 2024; : 80 doi: 10.4274/globecc.galenos.2023.64936
33
Hao Fu, Ping Li, Jie Yang, Hui Jiang. Comparative Study of Different Inflammation Definition Methods of GLIM in the Diagnosis of Malnutrition in Patients with Acute PancreatitisInternational Journal of General Medicine 2024; : 4883 doi: 10.2147/IJGM.S485400
34
Mehmet Suat Yalçın, SERKAN YALAKİ. Novel markers for mortality in patients with acute pancreatitis: NLR and PLR at the 48th hourJournal of Surgery and Medicine 2019;  doi: 10.28982/josam.658773
35
希阳 胡. Correlation between NLR/LMR/PLR and Prognosis of Patients with Gastric CancerAdvances in Clinical Medicine 2022; 12(05): 4240 doi: 10.12677/ACM.2022.125614
36
Wenyan Liao, Guangwei Tao, Guodong Chen, Jun He, Chunfen Yang, Xiaohua Lei, Shuo Qi, Jiafeng Hou, Yi Xie, Can Feng, Xinmiao Jiang, Xin Deng, Chengming Ding. A novel clinical prediction model of severity based on red cell distribution width, neutrophil-lymphocyte ratio and intra-abdominal pressure in acute pancreatitis in pregnancyBMC Pregnancy and Childbirth 2023; 23(1) doi: 10.1186/s12884-023-05500-0
37
Xiao Han, Mao-neng Hu, Peng Ji, Yun-feng Liu, Jincheng Wang. Construction and alidation of a severity prediction model for acute pancreatitis based on CT severity index: A retrospective case-control studyPLOS ONE 2024; 19(5): e0303684 doi: 10.1371/journal.pone.0303684
38
Adithya V Naragund, Rohith Muddasetty, Anil K, Vinay Kumar K M, Sharath S Kumar. NEUTROPHIL-LYMPHOCYTE RATIO'S ROLE IN FORETELLING MILD ACUTE PANCREATITIS: TERTIARY CARE CENTRE STUDY.INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH 2022; : 67 doi: 10.36106/ijsr/9402005
39
Pankaj Gupta, Gaurav Chayan Das, Akash Bansal, Jayanta Samanta, Harshal S Mandavdhare, Vishal Sharma, Shano Naseem, Vikas Gupta, Thakur Deen Yadav, Usha Dutta, Neelam Varma, Manavjit Singh Sandhu, Rakesh Kochhar. Value of neutrophil-lymphocyte ratio in evaluating response to percutaneous catheter drainage in patients with acute pancreatitisWorld Journal of Clinical Cases 2022; 10(1): 91-103 doi: 10.12998/wjcc.v10.i1.91
40
M. R. Sarkarova, M. V. Maevskaya. Prognostic and diagnostic value of the ratio of neutrophils to lymphocytes of patients with diseases of the gastrointestinal tract and liverMeditsinskiy sovet = Medical Council 2022; (7): 60 doi: 10.21518/2079-701X-2022-16-7-60-68
41
Zhihua Lu, Xiangping Chen, Huiqing Ge, Man Li, Binbin Feng, Donghai Wang, Feng Guo, Roberto Caronna. Neutrophil-Lymphocyte Ratio in Patients with Hypertriglyceridemic Pancreatitis Predicts Persistent Organ FailureGastroenterology Research and Practice 2022; 2022: 1 doi: 10.1155/2022/8333794
42
Rommel Sandhyav, Nihar Mohapatra, Nikhil Agrawal, Yashwant Patidar, Asit Arora, Tushar Kanti Chattopadhyay. Diffusion weighted MRI and neutrophil lymphocyte ratio non‐invasively predict infection in pancreatic necrosis: a pilot studyANZ Journal of Surgery 2024;  doi: 10.1111/ans.19301
43
M Harazim, J Chvojka. What the blood count hidesAnesteziologie a intenzivní medicína 2021; 32(2): 109 doi: 10.36290/aim.2021.027
44
Greta Maria Dancu, Alina Popescu, Roxana Sirli, Mirela Danila, Felix Bende, Cristi Tarta, Ioan Sporea. The BISAP score, NLR, CRP, or BUN: Which marker best predicts the outcome of acute pancreatitis?Medicine 2021; 100(51): e28121 doi: 10.1097/MD.0000000000028121
45
Arianna Miglio, Carlotta Valente, Carlo Guglielmini. Red Blood Cell Distribution Width as a Novel Parameter in Canine Disorders: Literature Review and Future ProspectiveAnimals 2023; 13(6): 985 doi: 10.3390/ani13060985
46
Wincy Wing-Sze Ng, Sin-Man Lam, Wing-Wa Yan, Hoi-Ping Shum. NLR, MLR, PLR and RDW to predict outcome and differentiate between viral and bacterial pneumonia in the intensive care unitScientific Reports 2022; 12(1) doi: 10.1038/s41598-022-20385-3
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Vlad Pădureanu, Daniel Caragea, Mirela Florescu, Ionela Vladu, Patricia Rădulescu, Dan Florescu, Dumitru Rădulescu, Rodica Pădureanu, Ion Efrem. Role of the SARS‑COV2 infection in the evolution of acute pancreatitis (Review)Biomedical Reports 2023; 19(1) doi: 10.3892/br.2023.1632
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Peter J. Lee, Georgios I. Papachristou, Cate Speake, Adam Lacy-Hulbert. Immune markers of severe acute pancreatitisCurrent Opinion in Gastroenterology 2024; 40(5): 389 doi: 10.1097/MOG.0000000000001053
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Haijiang Zhou, Xue Mei, Xinhua He, Tianfei Lan, Shubin Guo. Severity stratification and prognostic prediction of patients with acute pancreatitis at early phaseMedicine 2019; 98(16): e15275 doi: 10.1097/MD.0000000000015275
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Qi Su, Qingzhi Wang, Yantian Cao. The early biomarker of immature granulocyte count in predicting right-side colonic complicated acute diverticulitis: a retrospective cohort studyBMC Gastroenterology 2024; 24(1) doi: 10.1186/s12876-024-03443-0
51
Qiongzhen Luo, Xinwei He, Pu Ning, Yali Zheng, Donghong Yang, Yu Xu, Ying Shang, Zhancheng Gao. Admission Pentraxin‐3 Level Predicts Severity of Community‐Acquired Pneumonia Independently of EtiologyPROTEOMICS – Clinical Applications 2019; 13(4) doi: 10.1002/prca.201800117
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Mikhael Giabicani, Emmanuel Weiss, Gerald Chanques, Caroline Lemaitre, Audrey De Jong, Steven Grangé, Richard Moreau, Gaël Piton, Catherine Paugam-Burtz, Samir Jaber, Fabienne Tamion. The prognostic value of the neutrophil-to-lymphocyte ratio in critically ill cirrhotic patientsEuropean Journal of Gastroenterology & Hepatology 2021; 33(1S): e341 doi: 10.1097/MEG.0000000000002063
53
Sang-Hoon Lee, Tae-Yoon Lee, Jong-Hyeon Jeong, Young-Koog Cheon. Clinical Significance of the Neutrophil–Lymphocyte Ratio as an Early Predictive Marker for Adverse Outcomes in Patients with Acute CholangitisMedicina 2022; 58(2): 255 doi: 10.3390/medicina58020255
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Carlo Guglielmini, Paolo Emidio Crisi, Antonio Maria Tardo, Roberta Di Maggio, Barbara Contiero, Andrea Boari, Federico Fracassi, Arianna Miglio. Prognostic Role of Red Cell Distribution Width and Other Routine Clinico-Pathological Parameters in Dogs with Acute PancreatitisAnimals 2022; 12(24): 3483 doi: 10.3390/ani12243483
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Utkarsh Pradeep, Dr Satish Mahajan. A cross-sectional study of neutrophil to lymphocyte ratio as a prognostic marker in acute organophosphorus poisoning in a tertiary care hospital in Central IndiaF1000Research 2024; 13: 387 doi: 10.12688/f1000research.144250.1
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Bahri Abaylı, Genco Gençdal, Şerife Değirmencioğlu. Correlation between neutrophil/lymphocyte ratio and Ranson score in acute pancreatitisJournal of Clinical Laboratory Analysis 2018; 32(6) doi: 10.1002/jcla.22437
57
Guangzhe Pian, Hao Li, Yongjun Piao. Clinical Significance of Inflammation Markers in Predicting the Severity of Acute PancreatitisPancreas 2021; 50(2): 201 doi: 10.1097/MPA.0000000000001749
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Yuchen Wang, Harry E. Fuentes, Bashar M. Attar, Palash Jaiswal, Melchor Demetria. Evaluation of the prognostic value of neutrophil to lymphocyte ratio in patients with hypertriglyceridemia-induced acute pancreatitisPancreatology 2017; 17(6): 893 doi: 10.1016/j.pan.2017.10.001
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Gökhan Aksel. ACİL SERVİSE KRONİK OBSTRÜKTİK AKCİĞER HASTALIĞI AKUT ALEVLENMESİ İLE BAŞVURAN HASTALARDA NÖTROFİL-LENFOSİT VE PLATELET-LENFOSİT ORANLARININ HASTA PROGNOZUNA ETKİSİKırıkkale Üniversitesi Tıp Fakültesi Dergisi 2018;  doi: 10.24938/kutfd.365409
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Lan Ling, Hai‐Feng Wang, Jing Li, Yan Li, Cheng‐Dong Gu. Downregulated microRNA‐92a‐3p inhibits apoptosis and promotes proliferation of pancreatic acinar cells in acute pancreatitis by enhancing KLF2 expressionJournal of Cellular Biochemistry 2020; 121(8-9): 3739 doi: 10.1002/jcb.29517
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Adrian Boicean, Victoria Birlutiu, Cristian Ichim, Samuel B. Todor, Adrian Hasegan, Ciprian Bacila, Adelaida Solomon, Adrian Cristian, Horatiu Dura. Predictors of Post-ERCP Pancreatitis (P.E.P.) in Choledochal Lithiasis ExtractionJournal of Personalized Medicine 2023; 13(9): 1356 doi: 10.3390/jpm13091356
62
Qing-Yun Zhu, Ruo-Meng Li, Yun-Peng Zhu, Dong-Liang Hao, Yan Liu, Jing Yu, Xue Yang, Yu-Shi Zhang, Tian-Jiao Lin, Xu Yan, Jian-Xin Zuo, Xin-Ting Pan. Early Predictors of Infected Pancreatic Necrosis in Severe Acute Pancreatitis: Implications of Neutrophil to Lymphocyte Ratio, Blood Procalcitonin Concentration, and Modified CT Severity IndexDigestive Diseases 2023; 41(4): 677 doi: 10.1159/000529366
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Dawei Xu, Tianshu Mei, Fei He. The neutrophil-to-lymphocyte ratio is associated with the frequency of delayed neurologic sequelae in patients with carbon monoxide poisoningScientific Reports 2023; 13(1) doi: 10.1038/s41598-023-47214-5
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Parmeshwar Ramesh Junare, Prasanta Debnath, Sujit Nair, Sanjay Chandnani, Suhas Udgirkar, Ravi Thange, Shubham Jain, Rahul Deshmukh, Partha Debnath, Pravin Rathi, Qais Contractor, Akshay Deshpande. Complete hemogram: simple and cost-effective in staging and predicting outcome in acute pancreatitisWiener klinische Wochenschrift 2021; 133(13-14): 661 doi: 10.1007/s00508-021-01821-2
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Filipa Malheiro, Margarida Leitão do Nascimento, Luís Miguel Borrego. Circulating Blood B and T Lymphocytes and Severity of Acute Pancreatitis: A Systematic Review ProtocolActa Médica Portuguesa 2024; 37(4): 274 doi: 10.20344/amp.20087
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Tetiana Formanchuk, Volodymyr Shaprinskiy, Andrii Formanchuk. Clinical and simple laboratory data associated with fatal outcomes in patients with acute pancreatitisActa Facultatis Medicae Naissensis 2022; 39(1): 14 doi: 10.5937/afmnai39-32308
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Gunay Yildiz, Fatih Selvi, Cihan Bedel, Okkes Zortuk, Umut Ogün Mutlucan. Systemic inflammation response index and systemic immune-inflammation index are associated with severity of acute pancreatitisJournal of Clinical Medicine of Kazakhstan 2023; 20(3): 44 doi: 10.23950/jcmk/13320