BPG is committed to discovery and dissemination of knowledge
Cited by in CrossRef
For: Billmeier U, Dieterich W, Neurath MF, Atreya R. Molecular mechanism of action of anti-tumor necrosis factor antibodies in inflammatory bowel diseases. World J Gastroenterol 2016; 22(42): 9300-9313 [PMID: 27895418 DOI: 10.3748/wjg.v22.i42.9300]
URL: https://www.wjgnet.com/1007-9327/full/v22/i42/9300.htm
Number Citing Articles
1
Jun-Jang Jin, Il-Gyu Ko, Lakkyong Hwang, Sang-Hoon Kim, Yong-Seok Jee, Hyeon Jeon, Su Bee Park, Jung Won Jeon. Simultaneous Treatment of 5-Aminosalicylic Acid and Treadmill Exercise More Effectively Improves Ulcerative Colitis in MiceInternational Journal of Molecular Sciences 2024; 25(10) doi: 10.3390/ijms25105076
2
Susanna Nikolaus, Georg H. Waetzig, Sven Butzin, Monika Ziolkiewicz, Natalie Al-Massad, Florian Thieme, Ulf Lövgren, Birgitte B. Rasmussen, Torsten M. Reinheimer, Dirk Seegert, Philip Rosenstiel, Silke Szymczak, Stefan Schreiber. Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseasesInternational Journal of Colorectal Disease 2018; 33(7) doi: 10.1007/s00384-018-3069-8
3
Lorena Ortega Moreno, Samuel Fernández-Tomé, Raquel Abalo. Biological Treatments in Inflammatory Bowel Disease: A Complex Mix of Mechanisms and ActionsBiologics 2021; 1(2) doi: 10.3390/biologics1020012
4
Supriya Roy, Suneela Dhaneshwar, Tarique Mahmood. Exploring the Potential of IL-1β Inhibitor Diacerein and its Combination with 5-aminosalicylic Acid for the Possible Ameliorating Effect in TNBSinduced Experimental Colitis in Wistar RatsCurrent Drug Therapy 2022; 17(2) doi: 10.2174/1574885517666220328142715
5
Lorenzo Bertani, Luca Antonioli, Matteo Fornai, Gherardo Tapete, Giovanni Baiano Svizzero, Santino Marchi, Corrado Blandizzi, Francesco Costa. Evaluation of cytokine levels as putative biomarkers to predict the pharmacological response to biologic therapy in inflammatory bowel diseasesMinerva Gastroenterologica e Dietologica 2020; 65(4) doi: 10.23736/S1121-421X.19.02621-7
6
Renata Curciarello, Guillermo H. Docena, Thomas T. MacDonald. The Role of Cytokines in the Fibrotic Responses in Crohn’s DiseaseFrontiers in Medicine 2017; 4 doi: 10.3389/fmed.2017.00126
7
Yulia Liubomirski, Shalom Lerrer, Tsipi Meshel, Dina Morein, Linor Rubinstein-Achiasaf, David Sprinzak, Stefan Wiemann, Cindy Körner, Marcelo Ehrlich, Adit Ben-Baruch. Notch-Mediated Tumor-Stroma-Inflammation Networks Promote Invasive Properties and CXCL8 Expression in Triple-Negative Breast CancerFrontiers in Immunology 2019; 10 doi: 10.3389/fimmu.2019.00804
8
Mayara Santa Rosa Lima, Vanessa Cristina Oliveira de Lima, Grasiela Piuvezam, Kesley Pablo Morais de Azevedo, Bruna Leal Lima Maciel, Ana Heloneida de Araújo Morais. Mechanisms of action of molecules with anti-TNF-alpha activity on intestinal barrier inflammationMedicine 2019; 98(39) doi: 10.1097/MD.0000000000017285
9
Ralley E. Prentice, Emily K. Wright, Emma Flanagan, Rod W. Hunt, Gregory T. Moore, Claudia A. Nold-Petry, Sally J. Bell, Marcel F. Nold, Rimma Goldberg. The Effect of In Utero Exposure to Maternal Inflammatory Bowel Disease and Immunomodulators on Infant Immune System Development and FunctionCellular and Molecular Gastroenterology and Hepatology 2023; 16(1) doi: 10.1016/j.jcmgh.2023.03.005
10
Axue Wu, Yuan Gao, Ruotong Kan, Pengfei Ren, Changhu Xue, Biao Kong, Qingjuan Tang. Alginate Oligosaccharides Prevent Dextran-Sulfate-Sodium-Induced Ulcerative Colitis via Enhancing Intestinal Barrier Function and Modulating Gut MicrobiotaFoods 2023; 12(1) doi: 10.3390/foods12010220
11
Xuhui Tong, Yuanyuan Zheng, Yu Li, Yongjian Xiong, Dapeng Chen. Soluble ligands as drug targets for treatment of inflammatory bowel diseasePharmacology & Therapeutics 2021; 226 doi: 10.1016/j.pharmthera.2021.107859
12
Arushi Kohli, Alan C Moss. Personalizing therapy selection in inflammatory bowel diseaseExpert Review of Clinical Immunology 2023; 19(4) doi: 10.1080/1744666X.2023.2185605
13
Zizhen Gong, Shengnan Zhao, Jiefei Zhou, Junkai Yan, Lingyu Wang, Xixi Du, Hui Li, Yingwei Chen, Wei Cai, Jin Wu. Curcumin alleviates DSS-induced colitis via inhibiting NLRP3 inflammsome activation and IL-1β productionMolecular Immunology 2018; 104 doi: 10.1016/j.molimm.2018.09.004
14
Johanna Pott, Agnieszka Martyna Kabat, Kevin Joseph Maloy. Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in MiceCell Host & Microbe 2018; 23(2) doi: 10.1016/j.chom.2017.12.017
15
Wilbert Bouwman, Wim Verhaegh, Anja van de Stolpe. Improved diagnosis of inflammatory bowel disease and prediction and monitoring of response to anti-TNF alpha treatment based on measurement of signal transduction pathway activityFrontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.1008976
16
Aleksandra Górecka, Agnieszka Jura-Półtorak, Ewa M. Koźma, Anna Szeremeta, Krystyna Olczyk, Katarzyna Komosińska-Vassev. Biochemical Modulators of Tight Junctions (TJs): Occludin, Claudin-2 and Zonulin as Biomarkers of Intestinal Barrier Leakage in the Diagnosis and Assessment of Inflammatory Bowel Disease ProgressionMolecules 2024; 29(19) doi: 10.3390/molecules29194577
17
Hagar Ben-Yaakov, Tsipi Meshel, Metsada Pasmanik-Chor, Cindy Körner, Adit Ben-Baruch. A Tumor Microenvironment-Driven Network Regulated by STAT3 and p65 Negatively Controls the Enrichment of Cancer Stem Cells in Human HR+/HER2− Breast CancerCancers 2023; 15(8) doi: 10.3390/cancers15082255
18
Noriko Iwamoto, Kotoko Yokoyama, Megumi Takanashi, Atsushi Yonezawa, Kazuo Matsubara, Takashi Shimada. Application of nSMOL coupled with LC‐MS bioanalysis for monitoring the Fc‐fusion biopharmaceuticals Etanercept and Abatacept in human serumPharmacology Research & Perspectives 2018; 6(4) doi: 10.1002/prp2.422
19
Don Husereau, Brian Feagan, Carl Selya-Hammer. Policy Options for Infliximab Biosimilars in Inflammatory Bowel Disease Given Emerging Evidence for SwitchingApplied Health Economics and Health Policy 2018; 16(3) doi: 10.1007/s40258-018-0371-0
20
Gisa Tiegs, Andrea K. Horst. TNF in the liver: targeting a central player in inflammationSeminars in Immunopathology 2022; 44(4) doi: 10.1007/s00281-022-00910-2
21
Marleen Bouhuys, Willem S. Lexmond, Patrick F. van Rheenen. De-Escalation of Anti-Tumor Necrosis Factor Alpha Agents and Reduction in Adverse Effects: A Systematic ReviewBiomedicines 2022; 10(5) doi: 10.3390/biomedicines10051034
22
Federica Gaiani, Bianca Maria Rotoli, Francesca Ferrari, Amelia Barilli, Rossana Visigalli, Maria Clotilde Carra, Gian Luigi de’Angelis, Nicola de’Angelis, Valeria Dall’Asta. Monocytes from infliximab-resistant patients with Crohn’s disease exhibit a disordered cytokine profileScientific Reports 2020; 10(1) doi: 10.1038/s41598-020-68993-1
23
Zainab Jan, Farah El Assadi, Dinesh Velayutham, Borbala Mifsud, Puthen Veettil Jithesh. Pharmacogenomics of TNF inhibitorsFrontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1521794
24
Linxia Xu, Wei Liu, Xixiang Huang, Tong Sun, Letian Mei, Man Liu, Zhi Ren, Meng Wang, Hailun Zheng, Qiangwu Wang, Dapeng Li, Qizhi Wang, Xiquan Ke. Sinomenine hydrochloride improves DSS-induced colitis in mice through inhibition of the Notch signaling pathwayBMC Gastroenterology 2024; 24(1) doi: 10.1186/s12876-024-03546-8
25
Junichi Ishida, Masakazu Saitoh, Jochen Springer. Single‐nucleotide polymorphisms in cachexia‐related genes: Can they optimize the treatment of cancer cachexia?Journal of Cachexia, Sarcopenia and Muscle 2017; 8(3) doi: 10.1002/jcsm.12214
26
Dong-mei Yin, Dai Yuan, Rui-jie Sun, Hong-zhi Xu, Shou-yong Hun, Xiao-hui Sui, Ning-ning Shan. Identification of ORM1, vWF, SPARC, and PPBP as immune-related proteins involved in immune thrombocytopenia by quantitative LC-MS/MSClinical Proteomics 2023; 20(1) doi: 10.1186/s12014-023-09413-0
27
Thomas Klag, Jan Wehkamp, Eduard Stange. Wirkmechanismen und Wirkung von Biologika und JAK-Inhibitoren bei CEDGastro-News 2019; 6(1) doi: 10.1007/s15036-019-0482-y
28
Alan C. Moss. Treatment of Inflammatory Bowel Disease with Biologics2018;  doi: 10.1007/978-3-319-60276-9_1
29
Vibeke Andersen, Axel Kornerup Hansen, Berit Lilienthal Heitmann. Potential Impact of Diet on Treatment Effect from Anti-TNF Drugs in Inflammatory Bowel DiseaseNutrients 2017; 9(3) doi: 10.3390/nu9030286
30
Kristin K. Jørgensen, Guro L. Goll, Joe Sexton, Nils Bolstad, Inge C. Olsen, Øivind Asak, Ingrid P. Berset, Ingrid M. Blomgren, Katrine Dvergsnes, Jon Florholmen, Svein O. Frigstad, Magne Henriksen, Jon Hagfors, Gert Huppertz-Hauss, Espen A. Haavardsholm, Rolf A. Klaasen, Bjørn Moum, Geir Noraberg, Ulf Prestegård, Jan H. Rydning, Liv Sagatun, Kathrine A. Seeberg, Roald Torp, Cecilia Vold, David J. Warren, Carl M. Ystrøm, Knut E. A. Lundin, Tore Kvien, Jørgen Jahnsen. Efficacy and Safety of CT-P13 in Inflammatory Bowel Disease after Switching from Originator Infliximab: Exploratory Analyses from the NOR-SWITCH Main and Extension TrialsBioDrugs 2020; 34(5) doi: 10.1007/s40259-020-00438-7
31
Batia Weiss, Shomron Ben-Horin, Atar Lev, Efrat Broide, Miri Yavzori, Adi Lahat, Uri Kopylov, Orit Picard, Rami Eliakim, Yulia Ron, Irit Avni-Biron, Anat Yerushalmy-Feler, Amit Assa, Raz Somech, Ariella Bar-Gil Shitrit. Immune function in newborns with in-utero exposure to anti-TNFα therapyFrontiers in Pediatrics 2022; 10 doi: 10.3389/fped.2022.935034
32
Raja Atreya, Markus F. Neurath, Britta Siegmund. Personalizing Treatment in IBD: Hype or Reality in 2020? Can We Predict Response to Anti-TNF?Frontiers in Medicine 2020; 7 doi: 10.3389/fmed.2020.00517
33
Shiro Nakamura. Advances in Medical Treatment for Crohn's Disease: Focusing on Molecular Targeted DrugsNihon Daicho Komonbyo Gakkai Zasshi 2024; 77(10) doi: 10.3862/jcoloproctology.77.501
34
Tomasz Pytrus, Hubert Paweł Szyller, Gabriela Augustynowicz, Maria Lasocka, Sonia Watras, Katarzyna Akutko. Is Routine Monitoring of TNF-α Inhibitor Levels and Antibodies in Pediatric IBD Justified in the Era of Personalized MedicineJournal of Clinical Medicine 2026; 15(11) doi: 10.3390/jcm15114098
35
Roberta Figueiroa Souza, Marcos Antônio Ferreira Caetano, Henrique Inhauser Riceti Magalhães, Patricia Castelucci. Study of tumor necrosis factor receptor in the inflammatory bowel diseaseWorld Journal of Gastroenterology 2023; 29(18): 2733-2746 doi: 10.3748/wjg.v29.i18.2733
36
Liliana Lykowska-Szuber, Michal Walczak, Agnieszka Dobrowolska, Marzena Skrzypczak-Zielinska. Apoptosis and inflammatory genes variants in primary non-response to anti-TNF therapy in Crohn’s disease patientsEuropean Journal of Gastroenterology & Hepatology 2023; 35(10) doi: 10.1097/MEG.0000000000002618
37
Seema Yadav, Narahari Narayan Palei, Subas Chandra Dinda, Arghya Kusum Dhar. Concepts in Pharmaceutical Biotechnology and Drug DevelopmentInterdisciplinary Biotechnological Advances 2024;  doi: 10.1007/978-981-97-1148-2_7
38
HoUng Kim, Rieke Alten, Luisa Avedano, Axel Dignass, Fernando Gomollón, Kay Greveson, Jonas Halfvarson, Peter M. Irving, Jørgen Jahnsen, Péter L. Lakatos, JongHyuk Lee, Souzi Makri, Ben Parker, Laurent Peyrin-Biroulet, Stefan Schreiber, Steven Simoens, Rene Westhovens, Silvio Danese, Ji Hoon Jeong. The Future of Biosimilars: Maximizing Benefits Across Immune-Mediated Inflammatory DiseasesDrugs 2020; 80(2) doi: 10.1007/s40265-020-01256-5
39
Na Wu, Xinchong Du, Zhao Peng, Zetian Zhang, Lijun Cui, Duo Li, Rui Wang, Maoyuan Ma. Silencing of peroxiredoxin 1 expression ameliorates ulcerative colitis in a rat modelJournal of International Medical Research 2021; 49(3) doi: 10.1177/0300060520986313
40
Anna Kofla-Dłubacz, Tomasz Pytrus, Katarzyna Akutko, Patrycja Sputa-Grzegrzółka, Aleksandra Piotrowska, Piotr Dzięgiel. Etiology of IBD—Is It Still a Mystery?International Journal of Molecular Sciences 2022; 23(20) doi: 10.3390/ijms232012445
41
Roberta Figueiroa Souza, Felipe Alexandre Machado, Marcos Antônio Ferreira Caetano, Caroline Bures De Paulo, Patricia Castelucci. Effect of Anti-TNF Monoclonal Antibody on Enteric Neurons and Enteric Glial Cells in Experimental ColitisDigestive Diseases and Sciences 2025; 70(4) doi: 10.1007/s10620-025-08872-9
42
Giampaolo Morciano, Giulia Pellielo, Esther Densu Agyapong, Cristina Pellegrino, Simone Patergnani, Davide Franceschini, Konstantinos Koutsikos, Leonardo Rigon, Paolo Pinton, Alessandro Rimessi. The importance of mitochondria and mitochondrial calcium signaling in health and disease: an updated outlook on inflammationJournal of Translational Medicine 2026; 24(1) doi: 10.1186/s12967-026-07783-1
43
Shima Hasanzadeh, Morgayn I. Read, Abigail R. Bland, Muhammed Majeed, Tannaz Jamialahmadi, Amirhossein Sahebkar. Curcumin: an inflammasome silencerPharmacological Research 2020; 159 doi: 10.1016/j.phrs.2020.104921
44
Qiuling Lin, Dingguo Zhang, Jian Zhang, Weixiang Luo, Zhenglei Xu, Jun Yao, Lisheng Wang. Identification of lncRNA DLEU2 as a potential diagnostic biomarker and anti-inflammatory target for ulcerative colitisFrontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.991448
45
Francesca Penagini, Luisa Lonoce, Luisa Abbattista, Valentina Silvera, Giulia Rendo, Lucia Cococcioni, Dario Dilillo, Valeria Calcaterra, Gian Vincenzo Zuccotti. Dual biological therapy and small molecules in pediatric inflammatory bowel diseasePharmacological Research 2023; 196 doi: 10.1016/j.phrs.2023.106935
46
Jill L. Kinzer, Troy A. Halseth, Jukyung Kang, Sang Yeop Kim, Preethi Kumaran, Michael Ford, Sergei Saveliev, St John Skilton, Anna Schwendeman. Physicochemical characterization and functionality comparison of Humira®(adalimumab), Remicade®(infliximab) and Simponi Aria®(golimumab)International Journal of Pharmaceutics 2023; 635 doi: 10.1016/j.ijpharm.2023.122646
47
Sonia Chadha. Exploring the interconnected pathobiology between Crohn's disease, ulcerative colitis and colorectal cancer through gene expression, pathway analysis and immune profilingHuman Gene 2025; 44 doi: 10.1016/j.humgen.2025.201404
48
Agata Michalak, Beata Kasztelan-Szczerbinska, Katarzyna Laskowska, Piotr Radwan, Marek Cybulski, Halina Cichoż-Lach. Efficacy of biological treatment in inflammatory bowel disease – a single-center experiencePolish Journal of Public Health 2019; 129(3) doi: 10.2478/pjph-2019-0024
49
Joel V. Chua, John W. Baddley. Infectious Complications in Biologic and Targeted Therapies2022;  doi: 10.1007/978-3-031-11363-5_5
50
Ladan Agharokh, Katherine Mamola, Andrew G. Yu, Annette L. Medina, Bhaskar Gurram, Julie Fuller, Jason Y. Park, Weina Chen, Veena Rajaram, Matthew R. Hammer, Jeff L. Waugh. Cachexia, chorea, and pain in chronic nonbacterial osteitis and inflammatory bowel disease: a case reportJournal of Medical Case Reports 2023; 17(1) doi: 10.1186/s13256-023-03894-1
51
Han Huang, Chenxiao Gan, Yan Cai, Lingkang Wu. Immunological relationship between Helicobacter pylori and anti-tumor necrosis factor α agents in inflammatory bowel diseaseCentral European Journal of Immunology 2024; 49(1) doi: 10.5114/ceji.2024.136376
52
Sudha B. Singh, Cody A. Braun, Amanda Carroll-Portillo, Cristina N. Coffman, Henry C. Lin. Sulfate-Reducing Bacteria Induce Pro-Inflammatory TNF-α and iNOS via PI3K/Akt Pathway in a TLR 2-Dependent MannerMicroorganisms 2024; 12(9) doi: 10.3390/microorganisms12091833
53
Vojtech Dotlacil, Stepan Coufal, Tereza Lerchova, Kristyna Zarubova, Barbora Kucerova, Helena Tlaskalova-Hogenova, Miloslav Kverka, Richard Skaba, Jiri Bronsky, Ondrej Hradsky, Michal Rygl. Intestinal tissue levels of anti-TNF alpha, antibodies, and cytokines in paediatric Crohn diseaseScientific Reports 2025; 15(1) doi: 10.1038/s41598-024-83858-7
54
Yuki Ozato, Tomoaki Hara, Sikun Meng, Hiromichi Sato, Shotaro Tatekawa, Mamoru Uemura, Takeshi Yabumoto, Shizuka Uchida, Kazuhiko Ogawa, Yuichiro Doki, Hidetoshi Eguchi, Hideshi Ishii. RNA methylation in inflammatory bowel diseaseCancer Science 2024; 115(3) doi: 10.1111/cas.16048
55
Raja Atreya, Markus F Neurath. IL-23 Blockade in Anti-TNF Refractory IBD: From Mechanisms to Clinical RealityJournal of Crohn's and Colitis 2022; 16(Supplement_2) doi: 10.1093/ecco-jcc/jjac007
56
Federica Crispino, Mauro Grova, Erica Maria Bruno, Noemi Monachino, Giuseppe Rizzo, Angelo Casà, Sara Renna, Fabio Salvatore Macaluso, Ambrogio Orlando. Spondyloarthropathy in Inflammatory Bowel Disease: From Pathophysiology to Pharmacological TargetsDrugs 2022; 82(11) doi: 10.1007/s40265-022-01750-y
57
Asma Boumaza, Soraya Mezouar, Matthieu Bardou, Didier Raoult, Jean-Louis Mège, Benoit Desnues. Tumor Necrosis Factor Inhibitors Exacerbate Whipple’s Disease by Reprogramming Macrophage and Inducing ApoptosisFrontiers in Immunology 2021; 12 doi: 10.3389/fimmu.2021.667357
58
Ling Zhang, Yihang Zhang, Jihong Pan. Immunopathogenic mechanisms of rheumatoid arthritis and the use of anti-inflammatory drugsIntractable & Rare Diseases Research 2021; 10(3) doi: 10.5582/irdr.2021.01022
59
Jinshun Zhu, Huan Yu, Longzhi Xie, Dujuan Shuai, Zhixian Huang, Yufei Chen, Chao Ni, Chang Jia, Xing Rong, Lifang Zhang, Maoping Chu. A novel format of TNF-α binding affibody molecule ameliorate coronary artery endothelial injury in a mouse model of Kawasaki diseaseInternational Journal of Biological Macromolecules 2024; 281 doi: 10.1016/j.ijbiomac.2024.136255
60
Yue Zeng, Xingyu Liu, Qing Yi, Gan Qiao, Lulu Wang, Li Chen, Ling Fan, Yao Li, Lingjing Duan, Liqiang Huang, Qian Zhuang, Yejiang Zhou, Yuxia Xiong. Free total rhubarb anthraquinones protect intestinal mucosal barrier of SAP rats via inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathwayJournal of Ethnopharmacology 2024; 326 doi: 10.1016/j.jep.2024.117873
61
Yaoyao Du, Lan Rong, Yuanhua Cong, Lan Shen, Ning Zhang, Bing Wang. Macrophage polarization: an effective approach to targeted therapy of inflammatory bowel diseaseExpert Opinion on Therapeutic Targets 2021; 25(3) doi: 10.1080/14728222.2021.1901079
62
Talal S. Alharbi, Ziyad S. Alshammari, Ziyad N. Alanzi, Fahad Althobaiti, Mohammed A. F. Elewa, Khalid S. Hashem, Mohammed M. H. Al-Gayyar. Therapeutic effects of genistein in experimentally induced ulcerative colitis in rats via affecting mitochondrial biogenesisMolecular and Cellular Biochemistry 2024; 479(2) doi: 10.1007/s11010-023-04746-8
63
Dan Pu, Zhe Zhang, Baisui Feng. Alterations and Potential Applications of Gut Microbiota in Biological Therapy for Inflammatory Bowel DiseasesFrontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.906419
64
Tamir Baram, Nino Oren, Nofar Erlichman, Tsipi Meshel, Adit Ben-Baruch. Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFα Receptors in Human Triple-Negative Breast CancerCancers 2022; 14(14) doi: 10.3390/cancers14143513
65
Florence Hoogewoud, Laura Kowalczuk, Elodie Bousquet, Antoine Brézin, Elodie Touchard, Ronald Buggage, Thierry Bordet, Francine Behar-Cohen. Les anti-TNF-α pour le traitement des uvéites non infectieusesmédecine/sciences 2020; 36(10) doi: 10.1051/medsci/2020160
66
Meng‐Tzu Weng, Chia‐Yueh Hsiung, Shu‐Chen Wei, Yunching Chen. Nanotechnology for Targeted Inflammatory Bowel Disease Therapy: Challenges and OpportunitiesWIREs Nanomedicine and Nanobiotechnology 2024; 16(5) doi: 10.1002/wnan.1999
67
Rosanne W Meijboom, Liese Barbier, Louise C Druedahl, Kati Sarnola, Hanna M Tolonen, Helga Gardarsdottir, Toine C G Egberts, Thijs J Giezen. Recommendations on TNFα inhibitor biosimilar use in clinical practice: a comparison of European gastroenterology IBD guidanceExpert Opinion on Biological Therapy 2023; 23(8) doi: 10.1080/14712598.2023.2189008
68
Wenqing Yu, Yumin Zhao, Yuwei Zhang, Yaqian Li, Yiren Yang, Junying Wang, Hui Wang, Hua Shi, Chuqiao Xiao, Mouming Zhao, Jie Gao. Gut microbial metabolites-mediated modulation of colitis in mice by three geographically varied dietary patternsFood Science and Human Wellness 2025; 14(12) doi: 10.26599/FSHW.2024.9250420
69
Francesca Burlo, Serena Pastore, Gabriele Stocco, Paolo Dalla Zuanna, Debora Curci, Tomoyuki Mizuno, Kei Irie, Andrea Taddio, Alberto Tommasini. Give weekly adalimumab a chance before discontinuing it: a retrospective clinical and pharmacokinetic analysis in pediatric rheumatologyArthritis Research & Therapy 2025; 27(1) doi: 10.1186/s13075-025-03688-4
70
Patricia Mae Garcia, Jeff Moore, David Kahan, Mee Young Hong. Effects of Vitamin D Supplementation on Inflammation, Colonic Cell Kinetics, and Microbiota in Colitis: A ReviewMolecules 2020; 25(10) doi: 10.3390/molecules25102300
71
Shyi-Jou Chen, Gu-Jiun Lin, Jing-Wun Chen, Kai-Chen Wang, Chiung-Hsi Tien, Chih-Fen Hu, Chia-Ning Chang, Wan-Fu Hsu, Hueng-Chuen Fan, Huey-Kang Sytwu. Immunopathogenic Mechanisms and Novel Immune-Modulated Therapies in Rheumatoid ArthritisInternational Journal of Molecular Sciences 2019; 20(6) doi: 10.3390/ijms20061332
72
Barbara Ruder, Raja Atreya, Christoph Becker. Tumour Necrosis Factor Alpha in Intestinal Homeostasis and Gut Related DiseasesInternational Journal of Molecular Sciences 2019; 20(8) doi: 10.3390/ijms20081887
73
H.B. Costa-Filho, T.M.A.L. Sales, S.M. Paula, L.A.D. Nicolau, M.L. Queiroga, A. Havt, P.M.G. Soares, A.L.R. Barbosa, M.H.L.P. Souza. Role of cyclooxygenases 1 and 2 in the maintenance of colonic mucosal integrity in an experimental colitis modelBrazilian Journal of Medical and Biological Research 2023; 56 doi: 10.1590/1414-431x2023e12946
74
J.W. Baddley, F. Cantini, D. Goletti, J.J. Gómez-Reino, E. Mylonakis, R. San-Juan, M. Fernández-Ruiz, J. Torre-Cisneros. ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Soluble immune effector molecules [I]: anti-tumor necrosis factor-α agents)Clinical Microbiology and Infection 2018; 24 doi: 10.1016/j.cmi.2017.12.025
75
Sung-Eun Kim, Il-Gyu Ko, Jun-Jang Jin, Lakkyong Hwang, Chang-Ju Kim, Sang-Hoon Kim, Jin-Hee Han, Jung Won Jeon, Anna Chiarini. Polydeoxyribonucleotide Exerts Therapeutic Effect by Increasing VEGF and Inhibiting Inflammatory Cytokines in Ischemic Colitis RatsBioMed Research International 2020; 2020(1) doi: 10.1155/2020/2169083
76
Chuan Zhang, Huiping Zhu, Hui Jie, Hengyue Ding, Hongwen Sun. Arbutin ameliorated ulcerative colitis of mice induced by dextran sodium sulfate (DSS)Bioengineered 2021; 12(2) doi: 10.1080/21655979.2021.2005746
77
E. A. Belousova, I. G. Kozlov, D. I. Abdulganieva, O. P. Alexeeva, I. V. Gubonina, A. A. Lishchinskaya, L. V. Tarasova, E. Yu. Chashkova, M. V. Shapina, O. S. Shifrin, O. B. Shchukina. Immunological aspects of determination of an adequate biological treatment sequence for inflammatory bowel diseases: the expert board statement (St. Petersburg, May 22, 2021)Almanac of Clinical Medicine 2021; 49(7) doi: 10.18786/2072-0505-2021-49-060
78
Shinya Toriumi, Yousuke Kurihara, Komei Shimokawa, Arihito Tanaka, Norito Araki, Osamu Kawai, Yasoo Sugiura, Yoshihiro Uesawa. Disproportionality Analysis and Timing of Drug-Associated Guillain–Barré Syndrome Onset Based on the Japanese Adverse Drug Event Report DatabasePharmaceuticals 2026; 19(5) doi: 10.3390/ph19050688
79
Annalisa Di Rienzo, Lisa Marinelli, Marilisa Pia Dimmito, Eleonora Chiara Toto, Antonio Di Stefano, Ivana Cacciatore. Advancements in Inflammatory Bowel Disease Management: From Traditional Treatments to Monoclonal Antibodies and Future Drug Delivery SystemsPharmaceutics 2024; 16(9) doi: 10.3390/pharmaceutics16091185
80
M. Eugenia Delgado, Thomas Brunner. The many faces of tumor necrosis factor signaling in the intestinal epitheliumGenes & Immunity 2019; 20(8) doi: 10.1038/s41435-019-0057-0
81
Vu Q. Nguyen, Kristin Eden, Holly A. Morrison, Megan B. Sammons, Kristin K. Knight, Siena Sorrentino, Rebecca M. Brock, Douglas J. Grider, Irving C. Allen, Dario Sorrentino. Noncanonical NF-κB Signaling Upregulation in Inflammatory Bowel Disease Patients is Associated With Loss of Response to Anti-TNF AgentsFrontiers in Pharmacology 2021; 12 doi: 10.3389/fphar.2021.655887
82
Marwa Ben-Khemis, Dan Liu, Coralie Pintard, Zhuoyao Song, Margarita Hurtado-Nedelec, Jean-Claude Marie, Jamel El-Benna, Pham My-Chan Dang. TNFα counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytesRedox Biology 2023; 67 doi: 10.1016/j.redox.2023.102898
83
Xiaolin Ye, Jie Wu, Jing Li, Hongyu Wang, Hon W. Koon. Anterior Gradient Protein 2 Promotes Mucosal Repair in Pediatric Ulcerative ColitisBioMed Research International 2021; 2021(1) doi: 10.1155/2021/6483860
84
María Chaparro, Adrià Aterido, Iván Guerra, Marisa Iborra, Jose Luis Cabriada, Luis Bujanda, Carlos Taxonera, Valle García-Sánchez, Ignacio Marín-Jiménez, Manuel Barreiro-de Acosta, Isabel Vera, Maria Dolores Martín-Arranz, Borja Hernández-Breijo, Francisco Mesonero, Laura Sempere, Fernando Gomollón, Joaquín Hinojosa, Fernando Bermejo, Belén Beltrán, Ainhoa Rodríguez-Pescador, Jesús María Banales, David Olivares, Patricia Aguilar-Melero, Luis Menchén, Rocío Ferreiro-Iglesias, Isabel Blazquez Gómez, Beatriz Benitez García, Luis G Guijarro, Alicia C Marin, David Bernardo, Sara Marsal, Antonio Julia, Javier P Gisbert. Functional rare variants influence the clinical response to anti-TNF therapy in Crohn’s diseaseTherapeutic Advances in Gastroenterology 2019; 12 doi: 10.1177/1756284819867848
85
Manuel Sutter, Petr Hruz, Jan Hendrik Niess. High Serum Creatine Kinase Levels in Infliximab and Vedolizumab-Treated Inflammatory Bowel Disease PatientsInflammatory Intestinal Diseases 2021; 6(3) doi: 10.1159/000518264
86
Iuliana Samoilă, Sorina Dinescu, Marieta Costache. Interplay between Cellular and Molecular Mechanisms Underlying Inflammatory Bowel Diseases Development—A Focus on Ulcerative ColitisCells 2020; 9(7) doi: 10.3390/cells9071647
87
Markus Ries, Brice Moulari, Maryam A. Shetab Boushehri, Mohamed Ehab Ali, Daniel Molnar, Arnaud Béduneau, Yann Pellequer, Alf Lamprecht. Adalimumab Decorated Nanoparticles Enhance Antibody Stability and Therapeutic Outcome in Epithelial Colitis TargetingPharmaceutics 2022; 14(2) doi: 10.3390/pharmaceutics14020352
88
Hung Hiep Huynh, Naoki Morita, Toshihiro Sakamoto, Takuya Katayama, Takuya Miyakawa, Masaru Tanokura, Yasunori Chiba, Reiko Shinkura, Jun-ichi Maruyama. Functional production of human antibody by the filamentous fungus Aspergillus oryzaeFungal Biology and Biotechnology 2020; 7(1) doi: 10.1186/s40694-020-00098-w
89
Mai Murakami, Michio Onizawa, Naoto Abe, Tomoaki Mochimaru, Chikako Saito, Rie Hikichi, Takefumi Uemura, Masayuki Sekimata, Hiromasa Ohira. N-glycosylation negatively regulates the expression of tumor necrosis factor (TNF) in mouse macrophageBiochemical and Biophysical Research Communications 2024; 737 doi: 10.1016/j.bbrc.2024.150897
90
Shijin Wu, Yuyang Zhou. Monoclonal antibody precision therapy targeting inflammation for bipolar disorder: a narrative reviewTherapeutic Advances in Psychopharmacology 2024; 14 doi: 10.1177/20451253241227772
91
Emanual Maverakis, Angelo V. Marzano, Stephanie T. Le, Jeffrey P. Callen, Marie-Charlotte Brüggen, Emmanuella Guenova, Joachim Dissemond, Kanade Shinkai, Sinéad M. Langan. Pyoderma gangrenosumNature Reviews Disease Primers 2020; 6(1) doi: 10.1038/s41572-020-0213-x
92
Linor Rubinstein-Achiasaf, Dina Morein, Hagar Ben-Yaakov, Yulia Liubomirski, Tsipi Meshel, Eti Elbaz, Orly Dorot, Edward Pichinuk, Michael Gershovits, Miguel Weil, Adit Ben-Baruch. Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer CellsCancers 2021; 13(6) doi: 10.3390/cancers13061472
93
Barrett O. Attarha, Radhika Sharma, Vinit H. Majmudar, Lee Shapiro, Andrew Flint, Peter Ghali. GI Diseases Associated with Rheumatological and Vasculitic ConditionsClinical Gastroenterology 2025;  doi: 10.1007/978-3-032-07868-1_20
94
Zhaofeng Tan, Haibin Xue, Yuli Sun, Chuanlong Zhang, Yonglei Song, Yuanfu Qi. The Role of Tumor Inflammatory Microenvironment in Lung CancerFrontiers in Pharmacology 2021; 12 doi: 10.3389/fphar.2021.688625
95
Raffaella Franca, Debora Curci, Marianna Lucafò, Giuliana Decorti, Gabriele Stocco. Therapeutic drug monitoring to improve outcome of anti-TNF drugs in pediatric inflammatory bowel diseaseExpert Opinion on Drug Metabolism & Toxicology 2019; 15(7) doi: 10.1080/17425255.2019.1630378
96
Laurence Chapuy, Marwa Bsat, Siranush Sarkizova, Manuel Rubio, Amélie Therrien, Evelyne Wassef, Mickael Bouin, Katarzina Orlicka, Audrey Weber, Nir Hacohen, Alexandra-Chloé Villani, Marika Sarfati. Two distinct colonic CD14+ subsets characterized by single-cell RNA profiling in Crohn's diseaseMucosal Immunology 2019; 12(3) doi: 10.1038/s41385-018-0126-0
97
Tamara Ortiz, Federico Argüelles-Arias, Matilde Illanes, Josefa-María García-Montes, Elena Talero, Laura Macías-García, Ana Alcudia, Victoria Vázquez-Román, Virginia Motilva, Manuel De-Miguel. Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn’s Disease by the Regulation of Antioxidant and Anti-Inflammatory PathwaysNutrients 2020; 12(6) doi: 10.3390/nu12061752
98
Beate Beyer, Nicole Walch, Alois Jungbauer, Nico Lingg. How Similar Is Biosimilar? A Comparison of Infliximab Therapeutics in Regard to Charge Variant Profile and Antigen Binding AffinityBiotechnology Journal 2019; 14(4) doi: 10.1002/biot.201800340
99
Michal Walczak, Liliana Lykowska-Szuber, Marianna Plucinska, Kamila Stawczyk-Eder, Oliwia Zakerska-Banaszak, Piotr Eder, Iwona Krela-Kazmierczak, Michal Michalak, Marek Zywicki, Wojciech M. Karlowski, Marlena Szalata, Agnieszka Dobrowolska, Ryszard Slomski, Marzena Skrzypczak-Zielinska. Is Polymorphism in the Apoptosis and Inflammatory Pathway Genes Associated With a Primary Response to Anti-TNF Therapy in Crohn’s Disease Patients?Frontiers in Pharmacology 2020; 11 doi: 10.3389/fphar.2020.01207
100
Lamiaa A. Hassan, Medhat A. Al‐Ghobashy, Samah S. Abbas. Evaluation of the pattern and kinetics of degradation of adalimumab using a stability‐indicating orthogonal testing protocolBiomedical Chromatography 2019; 33(12) doi: 10.1002/bmc.4676
101
Meenu Wadhwa, Chris Bird, Eleanor Atkinson, Isabelle Cludts, Peter Rigsby. The First WHO International Standard for Adalimumab: Dual Role in Bioactivity and Therapeutic Drug MonitoringFrontiers in Immunology 2021; 12 doi: 10.3389/fimmu.2021.636420
102
Joanna Grudzinska-Goebel, Karin Benstein, Karien Bloem, Kyra J. Cowan, Boris Gorovits, Maria Jadhav, Melody Janssen, Vibha Jawa, Andrea Kiessling, Daniel Kramer, Arno Kromminga, Marcel van der Linden, Susana Liu, Gregor P. Lotz, Linlin Luo, Mantas Malisauskas, Céline Marban-Doran, Daniel T. Mytych, Elisa Oquendo Cifuentes, Susanne Pippig, Sandra Ribes, Myrthe Rouwette, Weiping Shao, Sophie Tourdot, Karin Nana Weldingh, Veerle Snoeck. Immunogenicity risk assessment for tailored mitigation and monitoring of biotherapeutics during development: recommendations from the European Immunogenicity PlatformFrontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1581153
103
Siyi Ni, Yingchao Liu, Jihong Zhong, Yan Shen. Identification and immunoinfiltration analysis of key genes in ulcerative colitis using WGCNAPeerJ 2024; 12 doi: 10.7717/peerj.16921
104
Marcella Gabrielle Mendes Machado, Cauê Benito Scarim, Cleverton Roberto de Andrade, Jean Leandro dos Santos, Chung Man Chin. Synthesis and anti-inflammatory intestinal activity of new glucocorticoid derivativesMedicinal Chemistry Research 2020; 29(2) doi: 10.1007/s00044-019-02474-7
105
Walter Reinisch, Stanley Cohen, Monica Ramchandani, Majed Khraishi, Jennifer Liu, Vincent Chow, Janet Franklin, Jean-Frederic Colombel. A Review of the Totality of Evidence for the Development and Approval of ABP 710 (AVSOLA), an Infliximab BiosimilarAdvances in Therapy 2022; 39(1) doi: 10.1007/s12325-021-01944-y
106
Boushra Abou Hjeily, Briana Candace Nevaneeth, Włodzimierz Samborski, Zoltán Szekanecz, Bogna Grygiel-Górniak. Inflammatory Pathways to Carcinogenesis: Deciphering the Rheumatoid Arthritis–Lung Cancer ConnectionCancers 2025; 17(8) doi: 10.3390/cancers17081330
107
Stephan Blüml. Biologika und „small molecules“ bei der rheumatoiden ArthritisZeitschrift für Rheumatologie 2020; 79(3) doi: 10.1007/s00393-020-00766-7
108
Olivier Lortholary, Mario Fernandez-Ruiz, John W Baddley, Oriol Manuel, Xavier Mariette, Kevin L Winthrop. Infectious complications of rheumatoid arthritis and psoriatic arthritis during targeted and biological therapies: a viewpoint in 2020Annals of the Rheumatic Diseases 2020; 79(12) doi: 10.1136/annrheumdis-2020-217092
109
Ramsey Saleem, Greg Cantin, Mats Wikström, Glen Bolton, Scott Kuhns, Helen J. McBride, Jennifer Liu. Analytical and Functional Similarity Assessment of ABP 710, a Biosimilar to Infliximab Reference ProductPharmaceutical Research 2020; 37(6) doi: 10.1007/s11095-020-02816-w
110
Alexandra S. Rasiuk, Scott R. Walsh, Lily Chan, Alicia M. Viloria-Petit, Sarah K. Wootton, Khalil Karimi, Byram W. Bridle. The Role of Type I Interferon Signaling in Regulating Cytokine Production and Cell Survival in Bone Marrow-Derived MacrophagesViral Immunology 2021; 34(7) doi: 10.1089/vim.2020.0308
111
E Antiga, R Maglie, W Volpi, B Bianchi, E Berti, A V Marzano, M Caproni. T helper type 1-related molecules as well as interleukin-15 are hyperexpressed in the skin lesions of patients with pyoderma gangrenosumClinical and Experimental Immunology 2017; 189(3) doi: 10.1111/cei.12989
112
Ty M. Mitchell, Nicole C. Burdick Sanchez, Jeff A. Carroll, Paul R. Broadway, Jerrad F. Legako, Brooke M. Bowen, Amy L. Petry. Prenatal lipopolysaccharide stimulation modulates gastrointestinal immunity and oxidative status in weaned pigsAmerican Journal of Physiology-Gastrointestinal and Liver Physiology 2025; 328(3) doi: 10.1152/ajpgi.00268.2024
113
Junsuke Uwada, Takashi Yazawa, Md Tariqul Islam, Md Rafiqul Islam Khan, Susanne M. Krug, Michael Fromm, Shin-ichiro Karaki, Yuichi Suzuki, Atsukazu Kuwahara, Hatsumi Yoshiki, Kiyonao Sada, Ikunobu Muramatsu, Takanobu Taniguchi. Activation of muscarinic receptors prevents TNF-α-mediated intestinal epithelial barrier disruption through p38 MAPKCellular Signalling 2017; 35 doi: 10.1016/j.cellsig.2017.04.007
114
Shengjie Ma, Jiaxin Zhang, Heshi Liu, Shuang Li, Quan Wang. The Role of Tissue-Resident Macrophages in the Development and Treatment of Inflammatory Bowel DiseaseFrontiers in Cell and Developmental Biology 2022; 10 doi: 10.3389/fcell.2022.896591
115
Jerry Z. Xu, Ramesh Kumar, Haoli Gong, Luyao Liu, Nicole Ramos-Solis, Yujing Li, Wilbert A. Derbigny, Craig R. Roy. Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial CellsInfection and Immunity 2019; 87(10) doi: 10.1128/IAI.00483-19
116
Baohai Liu, Xuehua Piao, Lianyi Guo, Guijun Wang, Weihua Sun, Leming Gao, Xuefeng Zheng, Yanli Fang, Steve Harakeh. A New Chinese Medicine Intestine Formula Greatly Improves the Effect of Aminosalicylate on Ulcerative ColitisEvidence-Based Complementary and Alternative Medicine 2017; 2017(1) doi: 10.1155/2017/7323129
117
Cecil Nick. Optimizing development of anti-TNFα biosimilars based on 10 years’ experienceExploration of Musculoskeletal Diseases 2025;  doi: 10.37349/emd.2025.100782
118
Katia Aquilano, Veronica Ceci, Angelo Gismondi, Susanna De Stefano, Federico Iacovelli, Raffaella Faraonio, Gabriele Di Marco, Noemi Poerio, Antonella Minutolo, Giuseppina Minopoli, Antonia Marcone, Maurizio Fraziano, Flavia Tortolici, Simona Sennato, Stefano Casciardi, Marina Potestà, Roberta Bernardini, Maurizio Mattei, Mattia Falconi, Carla Montesano, Stefano Rufini, Antonella Canini, Daniele Lettieri-Barbato. Adipocyte metabolism is improved by TNF receptor-targeting small RNAs identified from dried nutsCommunications Biology 2019; 2(1) doi: 10.1038/s42003-019-0563-7
119
Songmao Zheng, Jin Niu, Brian Geist, Damien Fink, Zhenhua Xu, Honghui Zhou, Weirong Wang. A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel disease modelmAbs 2020; 12(1) doi: 10.1080/19420862.2020.1813962
120
Rachel K. Lim, Dina A. Fisher, Stephen K. Field. TuberculosisIntegrated Science 2023; 11 doi: 10.1007/978-3-031-15955-8_32
121
Haruhiko Ogata, Takashi Hagiwara, Takeshi Kawaberi, Mariko Kobayashi, Toshifumi Hibi. Safety and effectiveness of adalimumab in the treatment of ulcerative colitis: results from a large-scale, prospective, multicenter, observational studyIntestinal Research 2021; 19(4) doi: 10.5217/ir.2020.00033
122
Chang-Cyuan Chen, Yu-An Lin, Kuan-Ting Liu, Chun-Yao Huang, Chun-Ming Shih, Yuan-Ti Lee, Jun-Liang Pan, Ai-Wei Lee. Navigating SARS-CoV-2-related immunopathology in Crohn’s disease: from molecular mechanisms to therapeutic challengesVirology Journal 2024; 21(1) doi: 10.1186/s12985-024-02529-1
123
Maria S Simon, Gara Arteaga-Henríquez, Ahmed Fouad Algendy, Timo Siepmann, Ben MW Illigens. Anti-Inflammatory Treatment Efficacy in Major Depressive Disorder: A Systematic Review of Meta-AnalysesNeuropsychiatric Disease and Treatment 2023;  doi: 10.2147/NDT.S385117
124
J. Scott Crowe, Kevin J. Roberts, Timothy M. Carlton, Luana Maggiore, Marion F. Cubitt, Simon Clare, Katherine Harcourt, Jill Reckless, Thomas T. MacDonald, Keith P. Ray, Anna Vossenkämper, Michael R. West. Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel DiseaseScientific Reports 2018; 8(1) doi: 10.1038/s41598-018-23277-7
125
Gregor Jezernik, Mario Gorenjak, Uroš Potočnik. MIF Variant rs755622 Is Associated with Severe Crohn’s Disease and Better Response to Anti-TNF Adalimumab TherapyGenes 2023; 14(2) doi: 10.3390/genes14020452
126
Tamir Baram, Linor Rubinstein-Achiasaf, Hagar Ben-Yaakov, Adit Ben-Baruch. Inflammation-Driven Breast Tumor Cell Plasticity: Stemness/EMT, Therapy Resistance and DormancyFrontiers in Oncology 2021; 10 doi: 10.3389/fonc.2020.614468
127
Mohammad Shehab, Fatema Alrashed, Ahmad Alfadhli, Khazna Alotaibi, Abdullah Alsahli, Hussain Mohammad, Preethi Cherian, Irina Al-Khairi, Thangavel Alphonse Thanaraj, Arshad Channanath, Hamad Ali, Mohamed Abu-Farha, Jehad Abubaker, Fahd Al-Mulla. Serological Response to BNT162b2 and ChAdOx1 nCoV-19 Vaccines in Patients with Inflammatory Bowel Disease on Biologic TherapiesVaccines 2021; 9(12) doi: 10.3390/vaccines9121471
128
Hong‐Gang Wang, Min‐Na Zhang, Xin Wen, Le He, Meng‐Hui Zhang, Jia‐Ling Zhang, Xiao‐Zhong Yang. Cepharanthine ameliorates dextran sulphate sodium‐induced colitis through modulating gut microbiotaMicrobial Biotechnology 2022; 15(8) doi: 10.1111/1751-7915.14059
129
Ziwen Yuan, Lihong Yang, Xiaosong Zhang, Peng Ji, Yongli Hua, Yanming Wei. Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier FunctionFrontiers in Pharmacology 2019; 10 doi: 10.3389/fphar.2019.01354
130
Xue Liu, Lin-Xiao Pan, Jia-Xian Pei, Tian Pu, Hong-Tao Wen, Ye Zhao. Role of serological biomarkers in evaluating and predicting endoscopic activity in inflammatory bowel diseaseWorld Journal of Gastroenterology 2025; 31(18): 104206 doi: 10.3748/wjg.v31.i18.104206
131
Cong-Qiu Chu. Blocking tumor necrosis factor paved the way for targeted therapeutics in inflammatory diseasesChinese Medical Journal 2021; 134(21) doi: 10.1097/CM9.0000000000001846
132
Anna Kofla-Dłubacz, Katarzyna Akutko, Elżbieta Krzesiek, Tatiana Jamer, Joanna Braksator, Paula Grębska, Tomasz Pytrus, Andrzej Stawarski. Selective Forms of Therapy in the Treatment of Inflammatory Bowel DiseasesJournal of Clinical Medicine 2022; 11(4) doi: 10.3390/jcm11040994
133
Renata Curciarello, Toni Sobande, Samantha Jones, Paolo Giuffrida, Antonio Di Sabatino, Guillermo H Docena, Thomas T MacDonald, Klaartje Kok. <p>Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies</p>Journal of Inflammation Research 2020;  doi: 10.2147/JIR.S234710
134
Hu Zhao, Taohui Ding, Yanglin Chen, Wenbin Yang, Jun Rao, Dan Liu, Bo Yi. Arecoline aggravates acute ulcerative colitis in mice by affecting intestinal microbiota and serum metabolitesFrontiers in Immunology 2023; 14 doi: 10.3389/fimmu.2023.1197922
135
Adam Saleh, Usman Ansari, Shaadi Abughazaleh, Kerri Glassner, Bincy P Abraham. Biological Therapies for the Management of Enteric Disease: Considerations for the ClinicianBiologics: Targets and Therapy 2022;  doi: 10.2147/BTT.S335697
136
Laura Clua‐Ferré, Roger Suau, Irene Vañó‐Segarra, Iris Ginés, Carolina Serena, Josep Manyé. Therapeutic potential of mesenchymal stem cell‐derived extracellular vesicles: A focus on inflammatory bowel diseaseClinical and Translational Medicine 2024; 14(11) doi: 10.1002/ctm2.70075
137
Carl L. Manthey, Beverley A. Moore, Yanqing Chen, Matthew J. Loza, Xiang Yao, Hao Liu, Stanley M. Belkowski, Holly Raymond-Parks, Paul J. Dunford, Francisco Leon, Jennifer E. Towne, Scott E. Plevy, Jörn Karhausen. The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitisPLOS ONE 2019; 14(11) doi: 10.1371/journal.pone.0223918
138
Irene Marafini, Silvia Sedda, Vincenzo Dinallo, Giovanni Monteleone. Inflammatory cytokines: from discoveries to therapies in IBDExpert Opinion on Biological Therapy 2019; 19(11) doi: 10.1080/14712598.2019.1652267
139
Alexander V Blagov, Marina D Sazonova, Anastasia I Ryzhkova, Vasily P Karagodin, Mikhail A Popov, Egor Yu Budnikov, Alessio L Ravani, Alexander N Orekhov, Margarita A Sazonova, Yuri V Arkhipenko. Analysis of the use of monoclonal antibodies in the treatment of Crohn’s diseaseAntibody Therapeutics 2026; 9(2) doi: 10.1093/abt/tbag006
140
Ramasatyaveni Geesala, Willow Schanz, Mikayla Biggs, Garima Dixit, Joseph Skurski, Prajwal Gurung, David K Meyerholz, David Elliott, Priya D Issuree, Thorsten Maretzky. Loss of RHBDF2 results in an early-onset spontaneous murine colitisJournal of Leukocyte Biology 2019; 105(4) doi: 10.1002/JLB.4A0718-283RR
141
Sabrina Nicolò, Ilaria Faggiani, Carmela Errico, Ferdinando D’Amico, Tommaso Lorenzo Parigi, Silvio Danese, Federica Ungaro. Translational characterization of immune pathways in inflammatory bowel disease: insights for targeted treatmentsExpert Review of Clinical Immunology 2025; 21(1) doi: 10.1080/1744666X.2024.2400300
142
Jill Coghlan, Hongliang He, Anna S. Schwendeman. Overview of Humira® Biosimilars: Current European Landscape and Future ImplicationsJournal of Pharmaceutical Sciences 2021; 110(4) doi: 10.1016/j.xphs.2021.02.003
143
Silvia L  Cruz-Martín-del-Campo, Claudia González-Espinosa, Ana Karen Ruiz-Quiñonez, César Javier Carranza-Aguilar. Tipos de muerte celular y sus implicaciones clínicasEl Residente 2020; 15(3) doi: 10.35366/95960
144
Xinxin Luo, Eduardo J. Villablanca. Type 2 immunity in intestinal homeostasis and inflammatory bowel diseaseBiochemical Society Transactions 2021; 49(5) doi: 10.1042/BST20210535
145
Simona Adesso, Giuseppina Autore, Andrea Quaroni, Ada Popolo, Lorella Severino, Stefania Marzocco. The Food Contaminants Nivalenol and Deoxynivalenol Induce Inflammation in Intestinal Epithelial Cells by Regulating Reactive Oxygen Species ReleaseNutrients 2017; 9(12) doi: 10.3390/nu9121343
146
Parsa S. Haque, Neeraj Kapur, Terrence A. Barrett, Arianne L. Theiss. Mitochondrial function and gastrointestinal diseasesNature Reviews Gastroenterology & Hepatology 2024; 21(8) doi: 10.1038/s41575-024-00931-2
147
Xianping Li, Mingzhe Wang, Chang Liu, Yuchun Xiao, Mengde Li, Chengjun Ban, Yuanming Huang, Miao Cheng, Liqiong Song, Guoxing Liu, Shan Lu, Chengxiang Wang, Zhihong Ren. Qingfeiyin Decoction Inhibits H1N1 Virus Infection via Modulation of Gut Microbiota and Inflammatory Pathways in a Murine ModelFrontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.874068
148
Elizabeth C. Rose, Jeremy M. Simon, Ismael Gomez-Martinez, Scott T. Magness, Jack Odle, Anthony T. Blikslager, Amanda L. Ziegler. Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestineAmerican Journal of Physiology-Gastrointestinal and Liver Physiology 2025; 328(3) doi: 10.1152/ajpgi.00194.2024
149
Leticia A. Shea, Jamshaid S. Ahmed. Highly effective treatment options for rheumatoid arthritis afforded by the availability of biosimilarsExploration of Musculoskeletal Diseases 2025;  doi: 10.37349/emd.2025.100787
150
Rui Han, Li Wang, Zhengang Zhao, Lijun You, Sandra Pedisić, Viktoryia Kulikouskaya, Zhiqi Lin. Polysaccharide from Gracilaria Lemaneiformis prevents colitis in Balb/c mice via enhancing intestinal barrier function and attenuating intestinal inflammationFood Hydrocolloids 2020; 109 doi: 10.1016/j.foodhyd.2020.106048
151
Yulia Liubomirski, Adit Ben-Baruch. Notch-Inflammation Networks in Regulation of Breast Cancer ProgressionCells 2020; 9(7) doi: 10.3390/cells9071576
152
Mikayla R. King, Roslyn A. Kemp, Safina Gadeock. Type I interferons in inflammatory bowel diseases: balancing barrier integrity, repair and inflammation in the intestinal epitheliumFrontiers in Medicine 2025; 12 doi: 10.3389/fmed.2025.1713424
153
Sophie Steeland, Claude Libert, Roosmarijn E. Vandenbroucke. A New Venue of TNF TargetingInternational Journal of Molecular Sciences 2018; 19(5) doi: 10.3390/ijms19051442
154
Ahmed Adekunle Owolabi, Iqra Qazi, Nadia Ahmed, Mariam Amro Alsayed, Muhammad Abu Zar, Taimour Rashid Choudhry, Dhanushan Gnanendran, Aqsa Khan, Amrutha Amrutha, Huzaifa Ahmad Cheema, Asma’a Munasar Ali Alsubari, Essam Rashad, Adnan Bhat, Faryal Altaf, Prasun K. Jalal. TNF antagonists withdrawal is not advised in patients with inflammatory bowel disease in remission: a systematic review and meta-analysis of randomized controlled trialsInternational Journal of Colorectal Disease 2025; 40(1) doi: 10.1007/s00384-025-05047-w
155
Jae Jun Park. Mechanism-based Drug Therapy of Inflammatory Bowel Disease With Special Reference to Rheumatic DiseaseJournal of Rheumatic Diseases 2020; 27(3) doi: 10.4078/jrd.2020.27.3.128
156
Jonathan L. Digby-Bell, Raja Atreya, Giovanni Monteleone, Nick Powell. Interrogating host immunity to predict treatment response in inflammatory bowel diseaseNature Reviews Gastroenterology & Hepatology 2020; 17(1) doi: 10.1038/s41575-019-0228-5
157
Alexandra Garten Schmitt, Thomas Erwes, Lisa M. Chirch. Inflammatory Bowel DiseaseClinical Gastroenterology 2021;  doi: 10.1007/978-3-030-81780-0_6
158
Robert Pietschner, Timo Rath, Markus F. Neurath, Raja Atreya. Current and Emerging Targeted Therapies for Ulcerative ColitisVisceral Medicine 2023; 39(2) doi: 10.1159/000530983
159
Junsuke Uwada, Hitomi Nakazawa, Ikunobu Muramatsu, Takayoshi Masuoka, Takashi Yazawa. Role of Muscarinic Acetylcholine Receptors in Intestinal Epithelial Homeostasis: Insights for the Treatment of Inflammatory Bowel DiseaseInternational Journal of Molecular Sciences 2023; 24(7) doi: 10.3390/ijms24076508
160
Yulia Liubomirski, Shalom Lerrer, Tsipi Meshel, Linor Rubinstein-Achiasaf, Dina Morein, Stefan Wiemann, Cindy Körner, Adit Ben-Baruch. Tumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast CancerFrontiers in Immunology 2019; 10 doi: 10.3389/fimmu.2019.00757
161
Miles P. Sparrow. Adalimumab in ulcerative colitis – efficacy, safety and optimization in the era of treat-to targetExpert Opinion on Biological Therapy 2017; 17(5) doi: 10.1080/14712598.2017.1309390
162
Suhail Nurbhai, Kevin J. Roberts, Timothy M. Carlton, Luana Maggiore, Marion F. Cubitt, Keith P. Ray, Jill Reckless, Hafeez Mohammed, Peter Irving, Thomas T. MacDonald, Anna Vossenkämper, Michael R. West, Gareth C. Parkes, J. Scott Crowe. Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis PatientsScientific Reports 2019; 9(1) doi: 10.1038/s41598-019-50545-x
163
Tong Zhang, Guo‐Yan Liu, Jing‐Long Cao, Yan‐Nan Li, Hui Xue, Hai‐Tao Wu, Cheng‐Hao Jin. Peimine‐induced apoptosis and inhibition of migration by regulating reactive oxygen species‐mediated MAPK/STAT3/NF‐κB and Wnt/β‐catenin signaling pathways in gastric cancer MKN‐45 cellsDrug Development Research 2022; 83(7) doi: 10.1002/ddr.21987
164
Swati Dobhal, Mukesh Nandave, Vinod Tiwari, Mamta F Singh. Unveiling the potential of Cepharanthine from plant to patient- A comprehensive review of phytochemistry, pharmacology and clinical investigationsJournal of Biologically Active Products from Nature 2024; 14(1) doi: 10.1080/22311866.2024.2312835
165
Jaslin P. James, Boye Schnack Nielsen, Ebbe Langholz, Mikkel Malham, Estrid Høgdall, Lene Buhl Riis. Estimating tissue-specific TNF mRNA levels prior to anti-TNFα treatment may support therapeutic optimisation in IBD patientsScandinavian Journal of Gastroenterology 2023; 58(11) doi: 10.1080/00365521.2023.2217313
166
Zejin Liu, Xinli Niu, Junpeng Wang. Naringenin as a natural immunomodulator against T cell-mediated autoimmune diseases: literature review and network-based pharmacology studyCritical Reviews in Food Science and Nutrition 2023; 63(32) doi: 10.1080/10408398.2022.2092054
167
Virginie Millet, Thomas Gensollen, Michael Maltese, Melanie Serrero, Nathalie Lesavre, Christophe Bourges, Christophe Pitaval, Sophie Cadra, Lionel Chasson, Thien Phong Vu Man, Marion Masse, Juan Jose Martinez-Garcia, Fabrice Tranchida, Laetitia Shintu, Konrad Mostert, Erick Strauss, Patricia Lepage, Mathias Chamaillard, Achille Broggi, Laurent Peyrin-Biroulet, Jean-Charles Grimaud, Philippe Naquet, Franck Galland. Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitisGut 2023; 72(6) doi: 10.1136/gutjnl-2021-325792
168
Andrea Picchianti-Diamanti, Maria M. Rosado, Raffaele D’Amelio. Infectious Agents and Inflammation: The Role of Microbiota in Autoimmune ArthritisFrontiers in Microbiology 2018; 8 doi: 10.3389/fmicb.2017.02696
169
Xiao-Zhi Li, Yun Qiu, Louisa Jeffery, Fen Liu, Rui Feng, Jin-Shen He, Jin-Yu Tan, Zi-Yin Ye, Si-Nan Lin, Subrata Ghosh, Marietta Iacucci, Min-Hu Chen, Ren Mao. Down-Regulation of Colonic ACE2 Expression in Patients With Inflammatory Bowel Disease Responding to Anti-TNF Therapy: Implications for COVID-19Frontiers in Medicine 2021; 7 doi: 10.3389/fmed.2020.613475
170
Bingran Wang, Jun Shen. NF-κB Inducing Kinase Regulates Intestinal Immunity and HomeostasisFrontiers in Immunology 2022; 13 doi: 10.3389/fimmu.2022.895636
171
Sang Hoon Lee, Jae Geun Song, Hyo-Kyung Han. Site-selective oral delivery of therapeutic antibodies to the inflamed colon via a folic acid-grafted organic/inorganic hybrid nanocomposite systemActa Pharmaceutica Sinica B 2022; 12(11) doi: 10.1016/j.apsb.2022.06.006
172
Marcel Vetter, Markus F. Neurath. Treatment Perspectives in Crohn’s DiseaseDigestion 2018; 98(3) doi: 10.1159/000488449
173
Lieven Pouillon, Johan Van Stappen, Peter Bossuyt, Silvio Danese, Laurent Peyrin-Biroulet. Should we use anti-tumor necrosis factor agents or vedolizumab as first-line biological therapy in ulcerative colitis?Best Practice & Research Clinical Gastroenterology 2018;  doi: 10.1016/j.bpg.2018.05.006
174
Jessica Codesido, Lara García-Varela, Xurxo García-Otero, Sheila Bouzón-Barreiro, Noemí Gómez-Lado, Francisco José Toja-Camba, Cristina Mondelo-García, Héctor Lazaré, Julia Baguña Torres, Jana Vidal-Otero, Santiago Medin-Aguerre, Alejandro Sanchez-Crespo, Francisco J. Otero-Espinar, José R. Herance, Anxo Fernández-Ferreiro, Pablo Aguiar. PET biodistribution study of subcutaneous and intravenous administration of adalimumab in an inflammatory bowel disease modelInternational Journal of Pharmaceutics 2025; 669 doi: 10.1016/j.ijpharm.2024.125011
175
Rishabh Hirawat, Mohd Aslam Saifi, Chandraiah Godugu. Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complicationsLife Sciences 2021; 267 doi: 10.1016/j.lfs.2020.118923
176
Marianna Lucafò, Raffaella Franca, Davide Selvestrel, Debora Curci, Letizia Pugnetti, Giuliana Decorti, Gabriele Stocco. Pharmacogenetics of treatments for inflammatory bowel diseaseExpert Opinion on Drug Metabolism & Toxicology 2018; 14(12) doi: 10.1080/17425255.2018.1551876
177
Beatriz del Rio, Begoña Redruello, Maria Fernandez, M. Cruz Martin, Victor Ladero, Miguel A. Alvarez. Lactic Acid Bacteria as a Live Delivery System for the in situ Production of Nanobodies in the Human Gastrointestinal TractFrontiers in Microbiology 2019; 9 doi: 10.3389/fmicb.2018.03179
178
Daisuke Tateiwa, Hideki Yoshikawa, Takashi Kaito. Cartilage and Bone Destruction in Arthritis: Pathogenesis and Treatment Strategy: A Literature ReviewCells 2019; 8(8) doi: 10.3390/cells8080818
179
Irene Soleto, Samuel Fernández-Tomé, Irene Mora-Gutiérrez, Montserrat Baldan-Martin, Cristina Ramírez, Cecilio Santander, José Andrés Moreno-Monteagudo, María José Casanova, Fernando Casals, Sergio Casabona, Irene Becerro, María Chaparro, David Bernardo, Javier P. Gisbert. Differential Effects of Anti-TNFα and Anti-α4β7 Drugs on Circulating Dendritic Cells Migratory Capacity in Inflammatory Bowel DiseaseBiomedicines 2022; 10(8) doi: 10.3390/biomedicines10081885
180
Soojung Hahn, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim. Protective effects of metformin in the pro-inflammatory cytokine induced intestinal organoids injury modelBiochemical and Biophysical Research Communications 2024; 690 doi: 10.1016/j.bbrc.2023.149291
181
Shiro Nakamura, Teita Asano, Hiroaki Tsuchiya, Kanami Sugimoto, Yuya Imai, Seiji Yokoyama, Yasuo Suzuki. Real-world data for golimumab treatment in patients with ulcerative colitis in Japan: interim analysis in post-marketing surveillanceIntestinal Research 2022; 20(3) doi: 10.5217/ir.2021.00032
182
Lili Hu, Handan Tan, Qingfeng Cao, Gangxiang Yuan, Changwei Huang, Guannan Su, Aize Kijlstra, Peizeng Yang. Weak association of a TNFRSF1A polymorphism with Behcet's disease in Chinese HanExperimental Eye Research 2020; 196 doi: 10.1016/j.exer.2020.108045
183
Hannah Schneider, Evelin Berger, Brendan Dolan, Beatriz Martinez-Abad, Liisa Arike, Thaher Pelaseyed, Gunnar C. Hansson. The human transmembrane mucin MUC17 responds to TNFα by increased presentation at the plasma membraneBiochemical Journal 2019; 476(16) doi: 10.1042/BCJ20190180
184
Mudassir Alam, Kashif Abbas. Disruption of Islet β-Cells Integrity via TNF-α Activated Apoptotic Signalling in Acute PancreatitisRomanian Journal of Preventive Medicine 2026; 4(1) doi: 10.3390/rjpm4010001