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For: Hu T, Li Z, Gao CY, Cho CH. Mechanisms of drug resistance in colon cancer and its therapeutic strategies. World J Gastroenterol 2016; 22(30): 6876-6889 [PMID: 27570424 DOI: 10.3748/wjg.v22.i30.6876]
URL: https://www.wjgnet.com/1007-9327/full/v22/i30/6876.htm
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Number Citing Articles
1
Jing Liang, Xiao-Feng Tian, Wei Yang. Effects of long non-coding RNA Opa-interacting protein 5 antisense RNA 1 on colon cancer cell resistance to oxaliplatin and its regulation of microRNA-137. World Journal of Gastroenterology 2020; 26(13): 1474-1489 doi: 10.3748/wjg.v26.i13.1474
2
Aditya Kumar, Yashika Uniyal, Roshan Kumar. Recent Advancement of Colorectal Cancer and Their Herbal Essential Oil Treatment. Journal for Research in Applied Sciences and Biotechnology 2022; 1(5) doi: 10.55544/jrasb.1.5.15
3
Morvarid Siri, Hamid Behrouj, Sanaz Dastghaib, Mozhdeh Zamani, Wirginia Likus, Sedigheh Rezaie, Jacek Hudecki, Saeed Khazayel, Marek J. Łos, Pooneh Mokarram, Saeid Ghavami. Casein Kinase-1-Alpha Inhibitor (D4476) Sensitizes Microsatellite Instable Colorectal Cancer Cells to 5-Fluorouracil via Authophagy Flux Inhibition. Archivum Immunologiae et Therapiae Experimentalis 2021; 69(1) doi: 10.1007/s00005-021-00629-2
4
Simona-Ruxandra Volovat, Iolanda Augustin, Daniela Zob, Diana Boboc, Florin Amurariti, Constantin Volovat, Cipriana Stefanescu, Cati Raluca Stolniceanu, Manuela Ciocoiu, Eduard Alexandru Dumitras, Mihai Danciu, Delia Gabriela Ciobanu Apostol, Vasile Drug, Sinziana Al Shurbaji, Lucia-Georgiana Coca, Florin Leon, Adrian Iftene, Paul-Corneliu Herghelegiu. Use of Personalized Biomarkers in Metastatic Colorectal Cancer and the Impact of AI. Cancers 2022; 14(19) doi: 10.3390/cancers14194834
5
Huan Liu, Guifang Li, Chenjie Shen, Xiaowei Qi, Yankui Liu, Dong Hua, Yong Mao, Ting Zhang. B7-H3-mediated deubiquitination stabilizing CYP1B1 expression promotes chemotherapy resistance in colorectal cancer. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2025; 1871(5) doi: 10.1016/j.bbadis.2025.167771
6
Like Zhong, Junfeng Zhu, Qi Shu, Gaoqi Xu, Chaoneng He, Luo Fang, Yanqing Liu. A Prognostic Cuproptosis-Related LncRNA Signature for Colon Adenocarcinoma. Journal of Oncology 2023; 2023 doi: 10.1155/2023/5925935
7
Fei Wang, Dinglan Wu, Jianxiang Chen, Shiliang Chen, Fengrong He, Housheng Fu, Qinghui Wu, Shuan Liu, Xionggen Li, Weifu Wang. Long non-coding RNA HOXA-AS2 promotes the migration, invasion and stemness of bladder cancer via regulating miR-125b/Smad2 axis. Experimental Cell Research 2019; 375(1) doi: 10.1016/j.yexcr.2018.11.005
8
Li‐guang Yang, Ming‐zheng Cao, Jie Zhang, Xiao‐yan Li, Qin‐li Sun. LncRNA XIST modulates HIF‐1A/AXL signaling pathway by inhibiting miR‐93‐5p in colorectal cancer. Molecular Genetics & Genomic Medicine 2020; 8(4) doi: 10.1002/mgg3.1112
9
Sheng Zhang, Treena Chatterjee, Carla Godoy, Ling Wu, Qingyun J. Liu, Kendra S. Carmon. GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism. Molecular Cancer Research 2019; 17(11) doi: 10.1158/1541-7786.MCR-19-0436
10
Ashraf N. Abdalla, Waleed H. Malki, Amal Qattan, Imran Shahid, Mohammad Akbar Hossain, Muhammad Ahmed. Chemosensitization of HT29 and HT29-5FU Cell Lines by a Combination of a Multi-Tyrosine Kinase Inhibitor and 5FU Downregulates ABCC1 and Inhibits PIK3CA in Light of Their Importance in Saudi Colorectal Cancer. Molecules 2021; 26(2) doi: 10.3390/molecules26020334
11
Zili Gu, Jie Yin, Candido G. Da Silva, Qi Liu, Luis J. Cruz, Ferry Ossendorp, Ewa Snaar-Jagalska. Therapeutic liposomal combination to enhance chemotherapy response and immune activation of tumor microenvironment. Journal of Controlled Release 2024; 373 doi: 10.1016/j.jconrel.2024.07.015
12
Lyudmila Ounpuu, Laura Truu, Igor Shevchuk, Vladimir Chekulayev, Aleksandr Klepinin, Andre Koit, Kersti Tepp, Marju Puurand, Egle Rebane-Klemm, Tuuli Käämbre. Comparative analysis of the bioenergetics of human adenocarcinoma Caco-2 cell line and postoperative tissue samples from colorectal cancer patients. Biochemistry and Cell Biology 2018; 96(6) doi: 10.1139/bcb-2018-0076
13
Yi-Ling Jiang, Xue Li, Ya-Wen Tan, Yu-Jing Fang, Kai-Yan Liu, Yi-Fan Wang, Ting Ma, Qing-Jian Ou, Cai-Xia Zhang. Docosahexaenoic acid inhibits the invasion and migration of colorectal cancer by reversing EMT through the TGF-β1/Smad signaling pathway. Food & Function 2024; 15(18) doi: 10.1039/D4FO02346C
14
Sara Shamekhi, Jalal Abdolalizadeh, Alireza Ostadrahimi, Seyyed Abolghasem Mohammadi, Abolfazl Barzegari, Hajie Lotfi, Esat Bonabi, Nosratollah Zarghami. Apoptotic Effect of Saccharomyces cerevisiae on Human Colon Cancer SW480 Cells by Regulation of Akt/NF-ĸB Signaling Pathway. Probiotics and Antimicrobial Proteins 2020; 12(1) doi: 10.1007/s12602-019-09528-7
15
Giulia Lori, Paolo Paoli, Angelo Pietro Femia, Erica Pranzini, Anna Caselli, Katia Tortora, Andrea Romagnoli, Giovanni Raugei, Giovanna Caderni. Morin‐dependent inhibition of low molecular weight protein tyrosine phosphatase (LMW‐PTP) restores sensitivity to apoptosis during colon carcinogenesis: Studies in vitro and in vivo, in an Apc‐driven model of colon cancer. Molecular Carcinogenesis 2019; 58(5) doi: 10.1002/mc.22962
16
Winnie Fong, Kenneth K. W. To. Drug repurposing to overcome resistance to various therapies for colorectal cancer. Cellular and Molecular Life Sciences 2019; 76(17) doi: 10.1007/s00018-019-03134-0
17
Zhuo Wu, Su Zhou, Dan Liang, Lan Mu. GPX2 acts as an oncogene and cudraflavone C has an anti-tumor effect by suppressing GPX2-dependent Wnt/β-catenin pathway in colorectal cancer cells. Naunyn-Schmiedeberg's Archives of Pharmacology 2024; 397(2) doi: 10.1007/s00210-023-02668-2
18
Lijun Ma, Fangfang Ai, Hongyan Xiao, Fang Wang, Lei Shi, Xuehong Bai, Yongzhao Zhu, Wenping Ma. Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells by inhibiting PI3K/AKT-dependent phosphomannose isomerase. Frontiers in Pharmacology 2024; 15 doi: 10.3389/fphar.2024.1367747
19
Raghvendra Pandey, Prashant Kumar Singh, Alok Kumar Shrivastava. Colon Cancer Diagnosis and Therapy. 2021;  doi: 10.1007/978-3-030-64668-4_13
20
Ping Li, Chun-Feng Feng, Peng-Fei Lyu, Fei Liu, Hui-Sheng Li, Li-Qun Zhang. Three-in-one DNA nanowheels for simultaneous tumor regression and drug resistance prevention in breast cancer model. Advanced Sensor and Energy Materials 2024; 3(3) doi: 10.1016/j.asems.2024.100104
21
WEI HU, THOMAS WARTMANN, MARCO STRECKER, ARISTOTELIS PERRAKIS, ROLAND CRONER, ARPAD SZALLASI, WENJIE SHI, ULF D. KAHLERT. Transient receptor potential channels as predictive marker and potential indicator of chemoresistance in colon cancer. Oncology Research 2024; 32(1) doi: 10.32604/or.2023.043053
22
Jianing Gong, Taoran Shi, Jinfeng Liu, Zerong Pei, Jingbo Liu, Xiaoliang Ren, Fengyun Li, Feng Qiu. Dual-drug codelivery nanosystems: An emerging approach for overcoming cancer multidrug resistance. Biomedicine & Pharmacotherapy 2023; 161 doi: 10.1016/j.biopha.2023.114505
23
Reza Seyyedi, Fereshteh Talebpour Amiri, Soghra Farzipour, Ehsan Mihandoust, Seyed Jalal Hosseinimehr. Mefenamic acid as a promising therapeutic medicine against colon cancer in tumor-bearing mice. Medical Oncology 2022; 39(2) doi: 10.1007/s12032-021-01618-3
24
Ankur Sood, Atul Dev, Soni Jignesh Mohanbhai, Nishith Shrimali, Meena Kapasiya, Avinash Chandra Kushwaha, Subhasree Roy Choudhury, Prasenjit Guchhait, Surajit Karmakar. Disulfide-Bridged Chitosan-Eudragit S-100 Nanoparticles for Colorectal Cancer. ACS Applied Nano Materials 2019; 2(10) doi: 10.1021/acsanm.9b01377
25
Kha Wai Hon, Nadiah Abu, Nurul-Syakima Ab Mutalib, Rahman Jamal. miRNAs and lncRNAs as Predictive Biomarkers of Response to FOLFOX Therapy in Colorectal Cancer. Frontiers in Pharmacology 2018; 9 doi: 10.3389/fphar.2018.00846
26
Ali Khalafizadeh, Seyedeh Donya Hashemizadegan, Fatemeh Shokri, Babak Bakhshinejad, Keyvan Jabbari, Mahsa Motavaf, Sadegh Babashah. Competitive endogenous RNA networks: Decoding the role of long non‐coding RNAs and circular RNAs in colorectal cancer chemoresistance. Journal of Cellular and Molecular Medicine 2024; 28(7) doi: 10.1111/jcmm.18197
27
P. Vasudeva Raju, RamaRao Malla. Colon Cancer Diagnosis and Therapy Vol. 3. 2022;  doi: 10.1007/978-3-030-72702-4_2
28
Sameena Gul, Muhammad Faisal Maqbool, Amara Maryam, Muhammad Khan, Hafiz Abdullah Shakir, Muhammad Irfan, Chaman Ara, Yongming Li, Tonghui Ma. Vitamin K: A novel cancer chemosensitizer. Biotechnology and Applied Biochemistry 2022; 69(6) doi: 10.1002/bab.2312
29
Qingmei Ye, Xin Zhou, Han Ren, Fangxuan Han, Rong Lin, Juan Li. An overview of the past decade of bufalin in the treatment of refractory and drug-resistant cancers: current status, challenges, and future perspectives. Frontiers in Pharmacology 2023; 14 doi: 10.3389/fphar.2023.1274336
30
Xilong Qian, Ying Wang, Zheng Liu, Fang Fang, Yulu Ma, Liu Zhou, Yanqiong Pan, Xiangsong Meng, Baofei Yan, Xingyu Zhu, Xiuxiu Wang, Jing Zhao, Shengjin Liu. Establishment of XRD fourier fingerprint identification method of realgar decoction pieces and its anti-tumor activity in tumor-in-situ transplanted mice. Journal of Ethnopharmacology 2024; 331 doi: 10.1016/j.jep.2024.118303
31
Shiyi Chen, Qian Li, Wei Zheng. Multiomics analyses of human colorectal cancer reveal changes in mitochondrial metabolism associated with chemotherapy resistance. Frontiers in Oncology 2025; 15 doi: 10.3389/fonc.2025.1625797
32
Saeedeh Keyvani‐Ghamsari, Khatereh Khorsandi, Asma Gul. Curcumin effect on cancer cells' multidrug resistance: An update. Phytotherapy Research 2020; 34(10) doi: 10.1002/ptr.6703
33
Rohitas Deshmukh. Modulation of Intestinal Flora as an Emerging Therapeutic Approach for the Treatment of Colon Cancer. Current Cancer Therapy Reviews 2025; 21(7) doi: 10.2174/0115733947302126240924050845
34
Folic acid-chitosan functionalized polymeric nanocarriers to treat colon cancer. International Journal of Biological Macromolecules 2023; 253 doi: 10.1016/j.ijbiomac.2023.127142
35
Sun-Ji Park, Sung-Woo Lee, Heegyum Moon, Su-Min Jung, Jin-Man Kim, Dong-Seok Lee, Eui-Hwan Choi. Amphiregulin drives EGFR-dependent genome stability in colorectal cancer and represents a targetable vulnerability. Oncogene 2026; 45(29) doi: 10.1038/s41388-026-03850-5
36
Zhenyu Xu, Lu Chen, Zhangang Xiao, Yanhong Zhu, Hui Jiang, Yan Jin, Cheng Gu, Yilai Wu, Lin Wang, Wen Zhang, Jian Zuo, Dexi Zhou, Jiajie Luan, Jing Shen. Potentiation of the anticancer effect of doxorubicinin drug-resistant gastric cancer cells by tanshinone IIA. Phytomedicine 2018; 51 doi: 10.1016/j.phymed.2018.05.012
37
Fatemeh Firouzi Amoodizaj, Sevda Baghaeifar, Elham Taheri, Mahdieh Farhoudi Sefidan Jadid, Maryam Safi, Nasrin Seyyed Sani, Saba Hajazimian, Alireza Isazadeh, Dariush Shanehbandi. RETRACTED: Enhanced anticancer potency of doxorubicin in combination with curcumin in gastric adenocarcinoma. Journal of Biochemical and Molecular Toxicology 2020; 34(6) doi: 10.1002/jbt.22486
38
Ninon Very, Tony Lefebvre, Ikram El Yazidi-Belkoura. Drug resistance related to aberrant glycosylation in colorectal cancer. Oncotarget 2018; 9(1) doi: 10.18632/oncotarget.22377
39
Alessio Carmignani, Matteo Battaglini, Attilio Marino, Francesca Pignatelli, Gianni Ciofani. Drug-Loaded Polydopamine Nanoparticles for Chemo/Photothermal Therapy against Colorectal Cancer Cells. ACS Applied Bio Materials 2024; 7(4) doi: 10.1021/acsabm.3c01203
40
Yong Yang, Guoxin Wang, Dajian Zhu, Yanfeng Huang, Yong Luo, Pengfei Su, Xiaowu Chen, Qian Wang. Epithelial-mesenchymal transition and cancer stem cell-like phenotype induced by Twist1 contribute to acquired resistance to irinotecan in colon cancer. International Journal of Oncology 2017; 51(2) doi: 10.3892/ijo.2017.4044
41
Dihydropyrimidinones: Recent Synthetic and Pharmacological Perspectives with Special Focus on Colon Cancer. Journal of Pharmaceutical Research and Development 2023;  doi: 10.47485/2694-5614.1017
42
Gülçin Yavuz Türel, Nilüfer Şahin Calapoğlu, Dilek Bayram, Meltem Özgöçmen, Vehbi Atahan Toğay, Eda Evgen Tülüceoğlu. Curcumin induces apoptosis through caspase dependent pathway in human colon carcinoma cells. Molecular Biology Reports 2022; 49(2) doi: 10.1007/s11033-021-06965-y
43
Pandian Sureshbabu Ram Kumar, Clayton Fernando Rencilin, Krishnan Sundar. Emerging nanomaterials for cancer immunotherapy. Exploration of Medicine 2021; 2(3) doi: 10.37349/emed.2021.00043
44
Shoumin Zhu, Shayan Khalafi, Zheng Chen, Julio Poveda, Dunfa Peng, Heng Lu, Mohammed Soutto, Jianwen Que, Monica Garcia-Buitrago, Alexander Zaika, Wael El-Rifai. Silencing of miR490–3p by H. pylori activates DARPP-32 and induces resistance to gefitinib. Cancer Letters 2020; 491 doi: 10.1016/j.canlet.2020.07.014
45
Yongchao Zhang, Zhuo-Xun Wu, Yuqi Yang, Jing-Quan Wang, Jun Li, Zoey Sun, Qiu-Xu Teng, Charles R. Ashby, Dong-Hua Yang. Poziotinib Inhibits the Efflux Activity of the ABCB1 and ABCG2 Transporters and the Expression of the ABCG2 Transporter Protein in Multidrug Resistant Colon Cancer Cells. Cancers 2020; 12(11) doi: 10.3390/cancers12113249
46
Xiang Li, Nan Wang, Yutong Wu, Yidan Liu, Ruoyu Wang. ALDH6A1 weakens the progression of colon cancer via modulating the RAS/RAF/MEK/ERK pathway in cancer cell lines. Gene 2022; 842 doi: 10.1016/j.gene.2022.146757
47
Roya Bazzaz, Hossain Bijanpour, Seyed M. B. Pirouzpanah, Parichehreh Yaghmaei, Nadereh Rashtchizadeh. Adjuvant therapy with γ‐tocopherol‐induce apoptosis in HT‐29 colon cancer via cyclin‐dependent cell cycle arrest mechanism. Journal of Biochemical and Molecular Toxicology 2019; 33(11) doi: 10.1002/jbt.22399
48
Mahdi Shadnoush, Mehrnaz Momenan, Veronique Seidel, Sascha Tierling, Nayeralsadat Fatemi, Ehsan Nazemalhosseini-Mojarad, Mohammad Tayefeh Norooz, Makan Cheraghpour. A comprehensive update on the potential of curcumin to enhance chemosensitivity in colorectal cancer. Pharmacological Reports 2025; 77(1) doi: 10.1007/s43440-024-00652-y
49
Batool Fatima, Maryam Jamil, Dilshad Hussain, Adeela Saeed, Fahmida Jabeen, Muhammad Salman Sajid, Muhammad Najam-ul-Haq. Biochemistry of Drug Resistance. 2021;  doi: 10.1007/978-3-030-76320-6_13
50
Li-Li Yang, Meng Li, Wei Huang, Peng-Tao Ren, Qing-Hui Yan, Ying-Hao Hao. ANP32B promotes colorectal cancer cell progression and reduces cell sensitivity to PRAP1 inhibitor through up-regulating HPF1. Heliyon 2024; 10(1) doi: 10.1016/j.heliyon.2023.e23829
51
Zheng Yang, Zhengye Liu, Mourboul Ablise, Aikebaier Maimaiti, Aizitiaili Aihaiti, Yusupuwajimu Alimujiang. Design and Synthesis of Novel α-Methylchalcone Derivatives, Anti-Cervical Cancer Activity, and Reversal of Drug Resistance in HeLa/DDP Cells. Molecules 2023; 28(23) doi: 10.3390/molecules28237697
52
Ankur Sood, Aastha Gupta, Ravi Bharadwaj, Pavana Ranganath, Neal Silverman, Garima Agrawal. Biodegradable disulfide crosslinked chitosan/stearic acid nanoparticles for dual drug delivery for colorectal cancer. Carbohydrate Polymers 2022; 294 doi: 10.1016/j.carbpol.2022.119833
53
Xiaoqing Wang, Meili Xi, Xing Lu, Xiangshi Tan. The Role and Mechanism of Innate Immune Regulation in Overcoming Oxaliplatin Resistance and Enhancing Anti-Tumor Efficacy in Colorectal Cancer. Pharmaceuticals 2025; 18(3) doi: 10.3390/ph18030317
54
Hedayat Hosseini, Amin Abbasi, Sahar Sabahi, Sousan Akrami, Arshid Yousefi-Avarvand. Assessing the Potential Biological Activities of Postbiotics Derived from Saccharomyces cerevisiae: An In Vitro Study. Probiotics and Antimicrobial Proteins 2024; 16(4) doi: 10.1007/s12602-023-10117-y
55
Janusz Matuszyk. MALAT1-miRNAs network regulate thymidylate synthase and affect 5FU-based chemotherapy. Molecular Medicine 2022; 28(1) doi: 10.1186/s10020-022-00516-2
56
Borong Zhou, Zhongchao Mai, Ying Ye, Yanan Song, Miao Zhang, Xinlin Yang, Wei Xia, Xiaofeng Qiu. The role of PYCR1 in inhibiting 5-fluorouracil-induced ferroptosis and apoptosis through SLC25A10 in colorectal cancer. Human Cell 2022; 35(6) doi: 10.1007/s13577-022-00775-5
57
Xiaoke Gu, Yanfei Jiang, Yingying Qu, Jing Chen, Dingding Feng, Chenglin Li, Xiaoxing Yin. Synthesis and biological evaluation of bifendate derivatives bearing 6,7-dihydro-dibenzo[c,e]azepine scaffold as potential P-glycoprotein and tumor metastasis inhibitors. European Journal of Medicinal Chemistry 2018; 145 doi: 10.1016/j.ejmech.2018.01.019
58
Monu Kumar Kashyap, Akash Ved, Rajiv Ratan Singh Yadav, Akhand Pratap Singh, Mahima Kushwaha, Karuna S. Shukla. The Cell Death and Signal Transduction Mechanisms in Colorectal Carcinogenesis: Recent Advances. Anti-Cancer Agents in Medicinal Chemistry 2023; 23(12) doi: 10.2174/1871520623666230328144748
59
Steven Forsythe, Naren Mehta, Mahesh Devarasetty, Hemamylammal Sivakumar, William Gmeiner, Shay Soker, Konstantinos Votanopoulos, Aleksander Skardal. Development of a Colorectal Cancer 3D Micro-tumor Construct Platform From Cell Lines and Patient Tumor Biospecimens for Standard-of-Care and Experimental Drug Screening. Annals of Biomedical Engineering 2020; 48(3) doi: 10.1007/s10439-019-02269-2
60
Sanaz Naghizadeh, Behzad Mansoori, Ali Mohammadi, Ebrahim Sakhinia, Behzad Baradaran. Gene Silencing Strategies in Cancer Therapy: An Update for Drug Resistance. Current Medicinal Chemistry 2019; 26(34) doi: 10.2174/0929867325666180403141554
61
Ralph A. de Groot, Daan Reedijk, Quentin Faucher, Silvia M. Mihăilă, Rosalinde Masereeuw. Strategies for overcoming ABC transporter-mediated multidrug resistance in colorectal cancer. American Journal of Physiology-Cell Physiology 2025; 329(3) doi: 10.1152/ajpcell.00412.2025
62
Xitong Su, Lei Wu, Mingming Hu, Wenxiang Dong, Meng Xu, Peng Zhang. Glycyrrhizic acid: A promising carrier material for anticancer therapy. Biomedicine & Pharmacotherapy 2017; 95 doi: 10.1016/j.biopha.2017.08.123
63
F.N.U. Aakash, Sunny Kumar, Aasta Kumari, F.N.U. Shweta, F.N.U. Rumela, F.N.U. Partab, Shivam Singla, Abida Parveen. Role of ETS2 gene in inflammatory bowel disease: A narrative review. Medicine 2025; 104(36) doi: 10.1097/MD.0000000000044234
64
Siddarth Agrawal, Marta Woźniak, Mateusz Łuc, Sebastian Makuch, Ewa Pielka, Anil Kumar Agrawal, Joanna Wietrzyk, Joanna Banach, Andrzej Gamian, Monika Pizon, Piotr Ziółkowski. Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-53145-x
65
Chao Yang, Shuoyang Huang, Fengyu Cao, Yongbin Zheng. Role of ferroptosis-related genes in prognostic prediction and tumor immune microenvironment in colorectal carcinoma. PeerJ 2021; 9 doi: 10.7717/peerj.11745
66
Ming‑Zhen Wang, Cheng‑Zhi Qiu, Wai‑Shi Yu, Yan‑Ta Guo, Chun‑Xiao Wang, Zhi‑Xiong Chen. GOLPH3 expression promotes the resistance of HT29 cells to 5‑fluorouracil by activating multiple signaling pathways. Molecular Medicine Reports 2017;  doi: 10.3892/mmr.2017.7877
67
Zhiming Shan, Na An, Jielin Qin, Junmei Yang, Hongqi Sun, Wei Yang. Long non-coding RNA Linc00675 suppresses cell proliferation and metastasis in colorectal cancer via acting on miR-942 and Wnt/β-catenin signaling. Biomedicine & Pharmacotherapy 2018; 101 doi: 10.1016/j.biopha.2018.02.123
68
Mohammad Kashif. Gene expression profiling to uncover prognostic and therapeutic targets in colon cancer, combined with docking and dynamics studies to discover potent anticancer inhibitor. Computational Biology and Chemistry 2025; 115 doi: 10.1016/j.compbiolchem.2025.108349
69
Korosh Morshedi, Sarina Borran, Mohammad Saeid Ebrahimi, Mohammad Jaber Masoud khooy, Zeynab Sadat Seyedi, Atefeh Amiri, Mohammad Abbasi‐Kolli, Maryam Fallah, Haroon Khan, Amirhossein Sahebkar, Hamed Mirzaei. Therapeutic effect of curcumin in gastrointestinal cancers: A comprehensive review. Phytotherapy Research 2021; 35(9) doi: 10.1002/ptr.7119
70
Neha Yadav, Rohitas Deshmukh, Rupa Mazumder. Recent Review on Potentials of Saponins in the Regulation of Inflammation in Colon Cancer: Current Progress and Future Prospects. The Natural Products Journal 2025; 15(5) doi: 10.2174/0122103155305824240607050942
71
Dongxin Tang, Zhu Yang, Fengxi Long, Li Luo, Bing Yang, Ruyi Zhu, Xianan Sang, Gang Cao. Inhibition of MALAT1 reduces tumor growth and metastasis and promotes drug sensitivity in colorectal cancer. Cellular Signalling 2019; 57 doi: 10.1016/j.cellsig.2019.01.013
72
Sona Vodenkova, Tomas Buchler, Klara Cervena, Veronika Veskrnova, Pavel Vodicka, Veronika Vymetalkova. 5-fluorouracil and other fluoropyrimidines in colorectal cancer: Past, present and future. Pharmacology & Therapeutics 2020; 206 doi: 10.1016/j.pharmthera.2019.107447
73
Sara Cherradi, Véronique Garambois, Johanna Marines, Augusto Faria Andrade, Alexandra Fauvre, Olivia Morand, Manon Fargal, Ferial Mancouri, Adeline Ayrolles-Torro, Nadia Vezzo-Vié, Marta Jarlier, Gerald Loussaint, Steve Huvelle, Nicolas Joubert, Thibault Mazard, Céline Gongora, Philippe Pourquier, Florence Boissière-Michot, Maguy Del Rio. Improving the response to oxaliplatin by targeting chemotherapy-induced CLDN1 in resistant metastatic colorectal cancer cells. Cell & Bioscience 2023; 13(1) doi: 10.1186/s13578-023-01015-5
74
Hande Maden, Hilal Calik, Rabia Yilmaz Ozturk, Selcen Ari Yuka, Betül Zehra Temur, Özge Can, Gizem Dinler Doğanay, Rabia Cakir. In silico–designed peptide targeting MDR1 (P-gp) restores chemosensitivity in colorectal cancer via chitosan nanoparticle delivery. Journal of Drug Delivery Science and Technology 2026; 117 doi: 10.1016/j.jddst.2026.108003
75
Jesica M. Ramírez-Villalobos, César I. Romo-Sáenz, Karla S. Morán-Santibañez, Patricia Tamez-Guerra, Ramiro Quintanilla-Licea, Alonso A. Orozco-Flores, Ricardo Romero-Arguelles, Reyes Tamez-Guerra, Cristina Rodríguez-Padilla, Ricardo Gomez-Flores. In Vitro Tumor Cell Growth Inhibition Induced by Lophocereus marginatus (DC.) S. Arias and Terrazas Endophytic Fungi Extracts. International Journal of Environmental Research and Public Health 2021; 18(18) doi: 10.3390/ijerph18189917
76
Arunaksharan Narayanankutty. PI3K/ Akt/ mTOR Pathway as a Therapeutic Target for Colorectal Cancer: A Review of Preclinical and Clinical Evidence. Current Drug Targets 2019; 20(12) doi: 10.2174/1389450120666190618123846
77
Shan-Ju Yeh, Shuo-Wei Chen, Bor-Sen Chen. Investigation of the Genome-Wide Genetic and Epigenetic Networks for Drug Discovery Based on Systems Biology Approaches in Colorectal Cancer. Frontiers in Genetics 2020; 11 doi: 10.3389/fgene.2020.00117
78
Narges Toolabi, Fattane Sam Daliri, Amir Mokhlesi, Mahmood Talkhabi. Identification of key regulators associated with colon cancer prognosis and pathogenesis. Journal of Cell Communication and Signaling 2022; 16(1) doi: 10.1007/s12079-021-00612-8
79
Wanying Liao, Junyu Long, Yiran Li, Fucun Xie, Ziyu Xun, Yanyu Wang, Xu Yang, Yunchao Wang, Kang Zhou, Xinting Sang, Haitao Zhao. Identification of an m6A-Related Long Noncoding RNA Risk Model for Predicting Prognosis and Directing Treatments in Patients With Colon Adenocarcinoma. Frontiers in Cell and Developmental Biology 2022; 10 doi: 10.3389/fcell.2022.910749
80
Sanaz Salek, Elham Moazamian, Afshin Mohammadi Bardbori, Seyedeh Azra Shamsdin. Anticancer effect of a combinatorial treatment of 5-fluorouracil and cell extract of some probiotic lactobacilli strains isolated from camel milk on colorectal cancer cells. Folia Microbiologica 2025; 70(5) doi: 10.1007/s12223-024-01228-2
81
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