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Jan 21, 2016 (publication date) through Mar 13, 2025
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Publication Name
World Journal of Gastroenterology
ISSN
1007-9327
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| For: | Shao YG, Ning K, Li F. Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer. World J Gastroenterol 2016; 22(3): 1224-1235 [PMID: 26811660 DOI: 10.3748/wjg.v22.i3.1224] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v22/i3/1224.htm |
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Yawen An, Hairong Wang, Aiwu Gao, Shufang Li, Jinli Yang, Boyang Li, Henan Lu. Effects of Sophora alopecuroides in a High-Concentrate Diet on the Liver Immunity and Antioxidant Function of Lambs According to Transcriptome Analysis. Animals 2024; 14(2): 182 doi: 10.3390/ani14020182
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| 3 |
Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors. PLOS ONE 2019; 14(11): e0225132 doi: 10.1371/journal.pone.0225132
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Payaningal R. Somanath, Jonathan Chernoff, Brian S. Cummings, Sandip M. Prasad, Harvey D. Homan. Targeting P21-Activated Kinase-1 for Metastatic Prostate Cancer. Cancers 2023; 15(8): 2236 doi: 10.3390/cancers15082236
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Yifang Dang, Ying Guo, Xiaoyu Ma, Xiaoyu Chao, Fei Wang, Linghao Cai, Zhongyi Yan, Longxiang Xie, Xiangqian Guo. Systemic analysis of the expression and prognostic significance of PAKs in breast cancer. Genomics 2020; 112(3): 2433 doi: 10.1016/j.ygeno.2020.01.016
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Kevin Chappell, Kanishka Manna, Charity L. Washam, Stefan Graw, Duah Alkam, Matthew D. Thompson, Maroof Khan Zafar, Lindsey Hazeslip, Christopher Randolph, Allen Gies, Jordan T. Bird, Alicia K Byrd, Sayem Miah, Stephanie D. Byrum. Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer. Molecular Omics 2021; 17(5): 677 doi: 10.1039/D1MO00117E
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Chetan K. Rane, Misaal Patel, Li Cai, William Senapedis, Erkan Baloglu, Audrey Minden. Decrypting the PAK4 transcriptome profile in mammary tumor forming cells using Next Generation Sequencing. Genomics 2018; 110(4): 248 doi: 10.1016/j.ygeno.2017.10.004
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Jiaxin Liang, Linda Oyang, Shan Rao, Yaqian Han, Xia Luo, Pin Yi, Jinguan Lin, Longzheng Xia, Jiaqi Hu, Shiming Tan, Lu Tang, Qing Pan, Yanyan Tang, Yujuan Zhou, Qianjin Liao. Rac1, A Potential Target for Tumor Therapy. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.674426
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Yixi Yuan, Hongyan Zhang, Danni Li, Ying Li, Fengzhan Lin, Yanzhi Wang, Hui Song, Xu Liu, Feng Li, Jian Zhang. PAK4 in cancer development: Emerging player and therapeutic opportunities. Cancer Letters 2022; 545: 215813 doi: 10.1016/j.canlet.2022.215813
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Xiang Li, Jiabin Li, Feng Li. P21 activated kinase 4 binds translation elongation factor eEF1A1 to promote gastric cancer cell migration and invasion. Oncology Reports 2017; 37(5): 2857 doi: 10.3892/or.2017.5543
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| 11 |
Jian Zhang, Hong-Yan Zhang, Jian Wang, Liang-Hao You, Rui-Zhi Zhou, Dong-Mei Zhao, Mao-Sheng Cheng, Feng Li. GL-1196 Suppresses the Proliferation and Invasion of Gastric Cancer Cells via Targeting PAK4 and Inhibiting PAK4-Mediated Signaling Pathways. International Journal of Molecular Sciences 2016; 17(4): 470 doi: 10.3390/ijms17040470
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| 12 |
Takahiro Yaguchi, Takafumi Onishi. Estrogen induces cell proliferation by promoting ABCG2-mediated efflux in endometrial cancer cells. Biochemistry and Biophysics Reports 2018; 16: 74 doi: 10.1016/j.bbrep.2018.10.005
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Min Yan Shi, Hwang Chan Yu, Chang Yeob Han, In Hyuk Bang, Ho Sung Park, Kyu Yun Jang, Sangkyu Lee, Jeong Bum Son, Nam Doo Kim, Byung-Hyun Park, Eun Ju Bae. p21-activated kinase 4 suppresses fatty acid β-oxidation and ketogenesis by phosphorylating NCoR1. Nature Communications 2023; 14(1) doi: 10.1038/s41467-023-40597-z
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| 14 |
Tianxiao Wu, Yu Pang, Jing Guo, Wenbo Yin, Mingyue Zhu, Chenzhou Hao, Kai Wang, Jian Wang, Dongmei Zhao, Maosheng Cheng. Discovery of 2-(4-Substituted-piperidin/piperazine-1-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-quinazoline-2,4-diamines as PAK4 Inhibitors with Potent A549 Cell Proliferation, Migration, and Invasion Inhibition Activity. Molecules 2018; 23(2): 417 doi: 10.3390/molecules23020417
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| 15 |
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| 16 |
Yiling Wang, Audrey Minden. Inhibition of NAMPT by PAK4 Inhibitors. International Journal of Molecular Sciences 2024; 25(18): 10138 doi: 10.3390/ijms251810138
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| 17 |
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| 18 |
Irene Ramos-Álvarez, Lingaku Lee, Robert T. Jensen. Group II p21-activated kinase, PAK4, is needed for activation of focal adhesion kinases, MAPK, GSK3, and β-catenin in rat pancreatic acinar cells. American Journal of Physiology-Gastrointestinal and Liver Physiology 2020; 318(3): G490 doi: 10.1152/ajpgi.00229.2019
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| 19 |
Rakesh Kumar, Rahul Sanawar, Xiaodong Li, Feng Li. Structure, biochemistry, and biology of PAK kinases. Gene 2017; 605: 20 doi: 10.1016/j.gene.2016.12.014
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| 20 |
Irene Ramos-Alvarez, R. T. Jensen. P21-activated kinase 4 in pancreatic acinar cells is activated by numerous gastrointestinal hormones/neurotransmitters and growth factors by novel signaling, and its activation stimulates secretory/growth cascades. American Journal of Physiology-Gastrointestinal and Liver Physiology 2018; 315(2): G302 doi: 10.1152/ajpgi.00005.2018
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| 21 |
H. Tsui, Q. Zeng, K. Chen, X. Zhang. Comprehensive Medicinal Chemistry III. 2017; : 408 doi: 10.1016/B978-0-12-409547-2.13815-6
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| 22 |
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| 23 |
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| 24 |
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