Academic Content and Language Evaluation of This Article
CrossCheck and Google Search of This Article
Academic Rules and Norms of This Article
Citation of this article
Corresponding Author of This Article
Research Domain of This Article
Article-Type of This Article
Open-Access Policy of This Article
Times Cited Counts in Google of This Article
Number of Hits and Downloads for This Article
- Total Article Views (18916)
All Articles published online
|
Featured Article
|
Publishing Process of This Article
|
Apr 28, 2016 (publication date) through Jan 25, 2026
Times Cited of This Article
Journal Information of This Article
Publication Name
World Journal of Gastroenterology
ISSN
1007-9327
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Szabo G. Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease. World J Gastroenterol 2016; 22(16): 4091-4108 [PMID: 27122661 DOI: 10.3748/wjg.v22.i16.4091] |
|
|
|
| ©2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA | |
| For: | Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Szabo G. Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease. World J Gastroenterol 2016; 22(16): 4091-4108 [PMID: 27122661 DOI: 10.3748/wjg.v22.i16.4091] |
|---|---|
| URL: | https://www.wjgnet.com/1007-9327/full/v22/i16/4091.htm |
| Number | Citing Articles |
| 1 |
Yong Xi, Zhijie Zhao, Yundong Zhou, Chengliang Yin, Yuxin Li, Xiao Xu, Wenyi Jin, Chengbin Lin, Kui Zhao, Junjie Kuang, Senlian Hong, Bentong Yu, João Conde, Shiyuan Liu, Weiyu Shen. Macrophage efferocytosis mediated by the TP63-RAC2 pathway promotes immunosuppressive remodeling in esophageal cancer. Cell Reports Medicine 2026; 7(1): 102529 doi: 10.1016/j.xcrm.2025.102529
|
| 2 |
Lin Zhu, Hai-Di Li, Jie-Jie Xu, Juan-Juan Li, Miao Cheng, Xiao-Ming Meng, Cheng Huang, Jun Li. Advancements in the Alcohol-Associated Liver Disease Model. Biomolecules 2022; 12(8): 1035 doi: 10.3390/biom12081035
|
| 3 |
Zhikun Zhao, Xiaoxiao Ma, Mingyan Li, Guangyuan Chen, Libo Qi, Shuang Song, Zhenhao Li, Chunhong Yan. Alcoholic Extracts from the Ganoderma Lucidum Fermentation Product Alleviated Ethanol-Induced Liver Injury, Gut Leakiness, and Gut Dysbiosis in Mice. Plant Foods for Human Nutrition 2025; 80(1) doi: 10.1007/s11130-024-01271-x
|
| 4 |
Ibrahim A. Komeil, Wessam M. El-Refaie, Mennatallah A. Gowayed, Samar O. El-Ganainy, Samar N. El Achy, Kristiina M. Huttunen, Ossama Y. Abdallah. Oral genistein-loaded phytosomes with enhanced hepatic uptake, residence and improved therapeutic efficacy against hepatocellular carcinoma. International Journal of Pharmaceutics 2021; 601: 120564 doi: 10.1016/j.ijpharm.2021.120564
|
| 5 |
Chien-Yu Lin, Evanthia Omoscharka, Yanli Liu, Kun Cheng. Establishment of a Rat Model of Alcoholic Liver Fibrosis with Simulated Human Drinking Patterns and Low-Dose Chemical Stimulation. Biomolecules 2023; 13(9): 1293 doi: 10.3390/biom13091293
|
| 6 |
Mohana Lakshmi Pentela, Archana Jorige. Animal Models of Alcoholic Liver Disease and Non-Alcoholic Fatty Liver Disease. Asian Journal of Pharmaceutical Research 2004; : 51 doi: 10.52711/2231-5691.2025.00009
|
| 7 |
Mengsi Liu, Mingying Zhou, Xueyi Ren, Yandi Xie. Establishment and application of murine models of alcoholic liver disease: A narrative review. Alcohol, Clinical and Experimental Research 2025; 49(2): 271 doi: 10.1111/acer.15520
|
| 8 |
Feifei Guo, Kang Zheng, Raquel Benedé‐Ubieto, Francisco Javier Cubero, Yulia A. Nevzorova. The Lieber‐DeCarli Diet—A Flagship Model for Experimental Alcoholic Liver Disease. Alcoholism: Clinical and Experimental Research 2018; 42(10): 1828 doi: 10.1111/acer.13840
|
| 9 |
Taojian Tu, Mario M. Alba, Aditi A. Datta, Handan Hong, Brittney Hua, Yunyi Jia, Jared Khan, Phillip Nguyen, Xiatoeng Niu, Pranav Pammidimukkala, Ielyzaveta Slarve, Qi Tang, Chenxi Xu, Yiren Zhou, Bangyan L. Stiles. Hepatic macrophage mediated immune response in liver steatosis driven carcinogenesis. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.958696
|
| 10 |
Ga-Young Kim, Dokyung Kim, Jaehyun Jeon, Wonhyo Seo, Seol Hee Park. Navigating liver cancer with mouse models: a comprehensive overview of HCC experimental systems. Journal of Liver Cancer 2025; 25(2): 239 doi: 10.17998/jlc.2025.08.21
|
| 11 |
Nevra Aydemir Celep, Semin Gedikli. Protective Effect of Silymarin on Liver in Experimental in the Sepsis Model of Rats. ACTA HISTOCHEMICA ET CYTOCHEMICA 2023; 56(1): 9 doi: 10.1267/ahc.22-00059
|
| 12 |
Shira Zelber-Sagi, Mazen Noureddin, Oren Shibolet. Lifestyle and Hepatocellular Carcinoma What Is the Evidence and Prevention Recommendations. Cancers 2021; 14(1): 103 doi: 10.3390/cancers14010103
|
| 13 |
Gyongyi Szabo. Alcohol and Cancer. Advances in Experimental Medicine and Biology 2018; 1032: 71 doi: 10.1007/978-3-319-98788-0_5
|
| 14 |
Jiaojiao Tang, Zijun Yan, Qiyu Feng, Lexing Yu, Hongyang Wang. The Roles of Neutrophils in the Pathogenesis of Liver Diseases. Frontiers in Immunology 2021; 12 doi: 10.3389/fimmu.2021.625472
|
| 15 |
Guoxiu Yan, Xuefu Wang, Cheng Sun, Xiaodong Zheng, Haiming Wei, Zhigang Tian, Rui Sun. Chronic Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis via Immune Disturbances. Scientific Reports 2017; 7(1) doi: 10.1038/s41598-017-02887-7
|
| 16 |
Jie Zhao, Maura O'Neil, Michael Schonfeld, Amberly Komatz, Steven A. Weinman, Irina Tikhanovich. Hepatocellular Protein Arginine Methyltransferase 1 Suppresses Alcohol‐Induced Hepatocellular Carcinoma Formation by Inhibition of Inducible Nitric Oxide Synthase. Hepatology Communications 2020; 4(6): 790 doi: 10.1002/hep4.1488
|
| 17 |
Renuka Sharma, Taqveema Ali, Ishwar Negi, Ashim Das, Ajay Duseja, Jyotdeep Kaur. Dietary modulations of folic acid affect the development of diethylnitrosamine induced hepatocellular carcinoma in a rat model. Journal of Molecular Histology 2021; 52(2): 335 doi: 10.1007/s10735-020-09955-9
|
| 18 |
Shi-Xuan Liu, Yan-Chao Du, Tao Zeng. A mini-review of the rodent models for alcoholic liver disease: shortcomings, application, and future prospects. Toxicology Research 2021; 10(3): 523 doi: 10.1093/toxres/tfab042
|
| 19 |
Arantza Lamas-Paz, Fengjie Hao, Leonard J Nelson, Maria Teresa Vázquez, Santiago Canals, Manuel Gómez del Moral, Eduardo Martínez-Naves, Yulia A Nevzorova, Francisco Javier Cubero. Alcoholic liver disease: Utility of animal models. World Journal of Gastroenterology 2018; 24(45): 5063-5075 doi: 10.3748/wjg.v24.i45.5063
|
| 20 |
Isaac Aguirre-Maldonado, Ema Elvira Herrera-López, Fernando López-Zenteno, Julio César Ramírez-Nava, Norma Arely López-Hernández, Jaime Arellanes-Robledo, Luis del Pozo-Yauner, Rebeca García-Román, Hilda Montero, Alfonso Alexander-Aguilera, Juana Martha Noyola-Díaz, Javier Camacho, Julio Isael Pérez-Carreón. Intriguing hepatoprotective effects of sucrose on hepatocellular carcinoma pathogenesis. Scientific Reports 2024; 14(1) doi: 10.1038/s41598-024-74991-4
|
| 21 |
Takefumi Kimura, Naoki Tanaka, Naoyuki Fujimori, Ayumi Sugiura, Tomoo Yamazaki, Satoru Joshita, Michiharu Komatsu, Takeji Umemura, Akihiro Matsumoto, Eiji Tanaka. Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis. World Journal of Gastroenterology 2018; 24(13): 1440-1450 doi: 10.3748/wjg.v24.i13.1440
|
| 22 |
Anuradha Ratna, Pranoti Mandrekar. Alcohol and Cancer: Mechanisms and Therapies. Biomolecules 2017; 7(3): 61 doi: 10.3390/biom7030061
|
| 23 |
Jisoo Kang, Seol Hee Park, Mushira Khanam, Seo Bhin Park, Sumin Shin, Wonhyo Seo. Impact of binge drinking on alcoholic liver disease. Archives of Pharmacal Research 2025; doi: 10.1007/s12272-025-01537-1
|
| 24 |
Xiu-Ning Zhang, Fan-Ge Meng, Yi-Ran Wang, Shi-Xuan Liu, Tao Zeng. Transformed ALDH2−/− hepatocytes by ethanol could serve as a useful tool for studying alcoholic hepatocarcinogenesis. Medical Hypotheses 2021; 146: 110366 doi: 10.1016/j.mehy.2020.110366
|
| 25 |
Jia’ning Shi, Shupeng Song, Shuangxing Li, Kaili Zhang, Yinghua Lan, Yongguo Li. TNF‐α/NF‐κB signaling epigenetically represses PSD4 transcription to promote alcohol‐related hepatocellular carcinoma progression. Cancer Medicine 2021; 10(10): 3346 doi: 10.1002/cam4.3832
|
| 26 |
Naima Zayed Mohamed, Hanan Farouk Aly, Hatem Abdel moneim El-Mezayen, Hadeer E. El-Salamony. Effect of co-administration of Bee honey and some chemotherapeutic drugs on dissemination of hepatocellular carcinoma in rats. Toxicology Reports 2019; 6: 875 doi: 10.1016/j.toxrep.2019.08.007
|
| 27 |
Yaojie Fu, Luca Maccioni, Xin Wei Wang, Tim F. Greten, Bin Gao. Alcohol-associated liver cancer. Hepatology 2024; 80(6): 1462 doi: 10.1097/HEP.0000000000000890
|
| 28 |
Fernando Magdaleno, Chuck Blajszczak, Natalia Nieto. Key Events Participating in the Pathogenesis of Alcoholic Liver Disease. Biomolecules 2017; 7(1): 9 doi: 10.3390/biom7010009
|
| 29 |
Futoshi Okada, Runa Izutsu, Keisuke Goto, Mitsuhiko Osaki. Inflammation-Related Carcinogenesis: Lessons from Animal Models to Clinical Aspects. Cancers 2021; 13(4): 921 doi: 10.3390/cancers13040921
|
| 30 |
Safaa S. Hassan, Wafaa M. Hosny, Mohamed A. Aboutabl, Dalia B. Fayed, Perihan A. Khalf‐Alla. Comparison of In Vitro and In Vivo Biological Screening of Nano‐Palladium (II) and Platinum (II)‐Based Compounds With DFT and Molecular Docking Study. Applied Organometallic Chemistry 2024; 38(12) doi: 10.1002/aoc.7713
|
| 31 |
Farid M. Sroor, Eman A. Younis, Hanan F. Aly. A Preclinical Study on 4-Methyl-N-((4-(trifluoromethoxy)phenyl) carbamoyl)-benzenesulfonamide as a Potent Chemotherapeutic Agent against Liver and Pancreatic Carcinogenesis in Rats: Immunohistochemical and Histopathological Studies. Medicinal Chemistry 2025; 21(7): 692 doi: 10.2174/0115734064308484240820080153
|
| 32 |
Helmut Karl Seitz. A narrative review on alcohol and alimentary tract cancer with special emphasis on acetaldehyde and oxidative stress. Zeitschrift für Gastroenterologie 2025; 63(09): 960 doi: 10.1055/a-2588-6849
|
| 33 |
Barbora Gromova, Viera Kupcova, Marie Serena Longhi, Roman Gardlik. Neutrophil-T cell cross talk in noninfectious liver diseases. American Journal of Physiology-Gastrointestinal and Liver Physiology 2026; 330(1): G10 doi: 10.1152/ajpgi.00192.2025
|
| 34 |
Hiroshi Matsushita, Akinobu Takaki. Alcohol and hepatocellular carcinoma. BMJ Open Gastroenterology 2019; 6(1): e000260 doi: 10.1136/bmjgast-2018-000260
|
| 35 |
Satdarshan P. Monga. Inside-Out or Outside-In: Choosing the Right Model of Hepatocellular Cancer. Gene Expression 2020; 20(2): 139 doi: 10.3727/105221620X15913805462476
|
| 36 |
Yao Wang, Haiyue Zhang, Qian Chen, Fangzhou Jiao, Chunxia Shi, Maohua Pei, Jian Lv, Hong Zhang, Luwen Wang, Zuojiong Gong. TNF‐α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury. Cell Proliferation 2020; 53(6) doi: 10.1111/cpr.12829
|
| 37 |
Abd Elraheem A. Elshater, Mahmoud Ashry, Hend Ahmed, Khaled G. Abdel-Wahhab, Fatma Adly Morsy, Rana Abd-Elstar. Ameliorative effect of costus ethanolic extract against Oxaliplatin-induced hepatotoxicity in adult rats. Egyptian Pharmaceutical Journal 2022; 21(1): 30 doi: 10.4103/epj.epj_44_21
|
| 38 |
Nour Y.S. Yassin, Sameh F. AbouZid, Asmaa M. El-Kalaawy, Tarek M. Ali, Mazen M. Almehmadi, Osama M. Ahmed. Silybum marianum total extract, silymarin and silibinin abate hepatocarcinogenesis and hepatocellular carcinoma growth via modulation of the HGF/c-Met, Wnt/β-catenin, and PI3K/Akt/mTOR signaling pathways. Biomedicine & Pharmacotherapy 2022; 145: 112409 doi: 10.1016/j.biopha.2021.112409
|
| 39 |
Fan-Ge Meng, Xiu-Ning Zhang, Shi-Xuan Liu, Yi-Ran Wang, Tao Zeng. Roles of peroxisome proliferator-activated receptor α in the pathogenesis of ethanol-induced liver disease. Chemico-Biological Interactions 2020; 327: 109176 doi: 10.1016/j.cbi.2020.109176
|
| 40 |
Hee Jeong Chun, Yeon Joo Shim, Young Hye Kwon. Cholic acid supplementation accelerates the progression of nonalcoholic fatty liver disease to the procarcinogenic state in mice fed a high-fat and high-cholesterol diet. The Journal of Nutritional Biochemistry 2022; 100: 108869 doi: 10.1016/j.jnutbio.2021.108869
|
| 41 |
Zachary J. Brown, Bernd Heinrich, Tim F. Greten. Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research. Nature Reviews Gastroenterology & Hepatology 2018; 15(9): 536 doi: 10.1038/s41575-018-0033-6
|
| 42 |
Jie Zhao, Maura O’Neil, Anusha Vittal, Steven A. Weinman, Irina Tikhanovich. PRMT1-Dependent Macrophage IL-6 Production Is Required for Alcohol-Induced HCC Progression. Gene Expression 2019; 19(2): 137 doi: 10.3727/105221618X15372014086197
|
| 43 |
Sayanta Sarkar, Abhishek Kumar Das, Semantee Bhattacharya, Ratan Gachhui, Parames C. Sil. Isorhamnetin exerts anti-tumor activity in DEN + CCl4-induced HCC mice. Medical Oncology 2023; 40(7) doi: 10.1007/s12032-023-02050-5
|
| 44 |
Jing Li, Xin Wang, Mudan Ren, Shuixiang He, Yan Zhao. Advances in experimental animal models of hepatocellular carcinoma. Cancer Medicine 2023; 12(14): 15261 doi: 10.1002/cam4.6163
|
| 45 |
Sakshi Anchan, Zaid Shaikh, Anupama Kumari, Rahul Thorat. Animal Models in Research. 2024; : 363 doi: 10.1007/978-981-97-0048-6_14
|
| 46 |
Yao Wang, Xun Li, Qian Chen, Fangzhou Jiao, Chunxia Shi, Maohua Pei, Luwen Wang, Zuojiong Gong. Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure. Journal of Inflammation Research 2021; : 1473 doi: 10.2147/JIR.S302391
|
| 47 |
Jie Zhao, Abby Adams, Ben Roberts, Maura O'Neil, Anusha Vittal, Timothy Schmitt, Sean Kumer, Josiah Cox, Zhuan Li, Steven A. Weinman, Irina Tikhanovich. Protein arginine methyl transferase 1– and Jumonji C domain‐containing protein 6–dependent arginine methylation regulate hepatocyte nuclear factor 4 alpha expression and hepatocyte proliferation in mice. Hepatology 2018; 67(3): 1109 doi: 10.1002/hep.29587
|