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For: Kikuchi M, Ushida Y, Shiozawa H, Umeda R, Tsuruya K, Aoki Y, Suganuma H, Nishizaki Y. Sulforaphane-rich broccoli sprout extract improves hepatic abnormalities in male subjects. World J Gastroenterol 2015; 21(43): 12457-12467 [PMID: 26604653 DOI: 10.3748/wjg.v21.i43.12457]
URL: https://www.wjgnet.com/1007-9327/full/v21/i43/12457.htm
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Number Citing Articles
1
Annie G. Cox, Seshini Gurusinghe, Rahana Abd Rahman, Bryan Leaw, Siow T. Chan, Joanne C. Mockler, Padma Murthi, Sarah A. Marshall, Rebecca Lim, Euan M. Wallace. Sulforaphane improves endothelial function and reduces placental oxidative stress in vitro. Pregnancy Hypertension 2019; 16 doi: 10.1016/j.preghy.2019.02.002
2
Pan Wang, Ziling Wang, Xinyuan Jin, Mengdi Zhang, Mengfan Shen, Dan Li. Oral Sulforaphane Intervention Protects Against Diabetic Cardiomyopathy in db/db Mice: Focus on Cardiac Lipotoxicity and Substrate Metabolism. Antioxidants 2025; 14(5) doi: 10.3390/antiox14050603
3
Khara Lucius. Botanical Medicine and Phytochemicals in Healthy Aging and Longevity—Part 2. Alternative and Complementary Therapies 2020; 26(2) doi: 10.1089/act.2020.29268.kha
4
Naoto Nagata, Liang Xu, Susumu Kohno, Yusuke Ushida, Yudai Aoki, Ryohei Umeda, Nobuo Fuke, Fen Zhuge, Yinhua Ni, Mayumi Nagashimada, Chiaki Takahashi, Hiroyuki Suganuma, Shuichi Kaneko, Tsuguhito Ota. Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice. Diabetes 2017; 66(5) doi: 10.2337/db16-0662
5
Yi Tan, Zhiguo Zhang, Chao Zheng, Kupper A. Wintergerst, Bradley B. Keller, Lu Cai. Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence. Nature Reviews Cardiology 2020; 17(9) doi: 10.1038/s41569-020-0339-2
6
Dana ElKhalifa, Nour Al-Ziftawi, Ahmed Awaisu, Feras Alali, Ashraf Khalil. Efficacy and tolerability of sulforaphane in the therapeutic management of cancers: a systematic review of randomized controlled trials. Frontiers in Oncology 2023; 13 doi: 10.3389/fonc.2023.1251895
7
Ivan A. Ross. Plant-Based Therapeutics, Volume 2. 2024;  doi: 10.1007/978-3-031-63681-3_10
8
Hyun Ju Kim, Min Sung Kwon, Hyelyeon Hwang, Ha-Sun Choi, WooJe Lee, Sang-Pil Choi, Haeun Jo, Sung Wook Hong. A Review of the Health Benefits of Kimchi Functional Compounds and Metabolites. Microbiology and Biotechnology Letters 2023; 51(4) doi: 10.48022/mbl.2310.10011
9
Emma F. Jacquier, Amira Kassis, Diana Marcu, Nikhat Contractor, Jina Hong, Chun Hu, Marissa Kuehn, Christopher Lenderink, Arun Rajgopal. Phytonutrients in the promotion of healthspan: a new perspective. Frontiers in Nutrition 2024; 11 doi: 10.3389/fnut.2024.1409339
10
Ryota Endo, Hiroshi Chikano, Etsuko Itabashi, Mitsuyo Kawasaki, Takayoshi Ohara, Tomohiro Kakizaki. Large insertion in radish GRS1 enhances glucoraphanin content in intergeneric hybrids, Raphanobrassica (Raphanus sativus L. x Brassica oleracea var. acephala). Frontiers in Plant Science 2023; 14 doi: 10.3389/fpls.2023.1132302
11
Juan Wang, Haixin Zhou. Protective effects of sulforaphane and aerobic exercise on acute alcoholic hepatic injury in mice. Saudi Journal of Biological Sciences 2020; 27(11) doi: 10.1016/j.sjbs.2020.07.014
12
Lu Zhang, Pengpu Wang, Mengxuan Shi, Zizhuang Fang, Junfu Ji, Xiaojun Liao, Xiaosong Hu, Fang Chen. The modulation of Luffa cylindrica (L.) Roem supplementation on gene expression and amino acid profiles in liver for alleviating hepatic steatosis via gut microbiota in high-fat diet-fed mice: insight from hepatic transcriptome analysis. The Journal of Nutritional Biochemistry 2020; 80 doi: 10.1016/j.jnutbio.2020.108365
13
Giulia Apprato, Camilla Fiz, Isabella Fusano, Loredana Bergandi, Francesca Silvagno. Natural Epigenetic Modulators of Vitamin D Receptor. Applied Sciences 2020; 10(12) doi: 10.3390/app10124096
14
Junduo Wu, Ziping Jiang, Haina Zhang, Wenzhao Liang, Wenlin Huang, Huan Zhang, Ying Li, Zhaohui Wang, Junnan Wang, Ye Jia, Bin Liu, Hao Wu. Sodium butyrate attenuates diabetes-induced aortic endothelial dysfunction via P300-mediated transcriptional activation of Nrf2. Free Radical Biology and Medicine 2018; 124 doi: 10.1016/j.freeradbiomed.2018.06.034
15
Naoto Nagata, Guanliang Chen, Liang Xu, Hitoshi Ando. An Update on the Chemokine System in the Development of NAFLD. Medicina 2022; 58(6) doi: 10.3390/medicina58060761
16
Manami Kodaka, Akito Kikuchi, Kotaro Kawahira, Haruhiko Kamada, Ryo Katsuta, Ken Ishigami, Tsukasa Suzuki, Yuji Yamamoto, Jun Inoue. Identification of a novel target of sulforaphane: Sulforaphane binds to acyl-protein thioesterase 2 (APT2) and attenuates its palmitoylation. Biochemical and Biophysical Research Communications 2024; 726 doi: 10.1016/j.bbrc.2024.150244
17
Yusuke Ushida, Chutinan Boonyapichest, Hiroyuki Suganuma, Mitsuru Tanaka, Toshiro Matsui. Paracellular Transport of Sulforaphane across Caco-2 Cell Monolayers. Food Science and Technology Research 2016; 22(1) doi: 10.3136/fstr.22.127
18
Ángel Abellán, Raúl Domínguez-Perles, Diego A. Moreno, Cristina García-Viguera. Sorting out the Value of Cruciferous Sprouts as Sources of Bioactive Compounds for Nutrition and Health. Nutrients 2019; 11(2) doi: 10.3390/nu11020429
19
Justin P. Chan, Brandon Lung, Megan Donnelly, Sohaib Z. Hashmi, Nitin Bhatia, Yu-Po Lee. Elevated Serum Alkaline Phosphatase is an Independent Predictor of Complications After Lumbar Spinal Fusion. World Neurosurgery 2024; 188 doi: 10.1016/j.wneu.2024.05.132
20
Yusuke Ushida, Hiroyuki Suganuma, Akinori Yanaka. Low-Dose of the Sulforaphane Precursor Glucoraphanin as a Dietary Supplement Induces Chemoprotective Enzymes in Humans. Food and Nutrition Sciences 2015; 6(17) doi: 10.4236/fns.2015.617165
21
Emiko Kikuchi, Chizumi Yamada, Yuri Yamaga, Kanae Oda, Nobunari Yukumatsu, Chiori Okuno, Noriaki Kishimoto, Akira Kubo, Naoaki Ishii, Yasuhiro Nishizaki. Roles of Registered Dietitians in the Fields of General and Anti-Aging Health Check-ups, and Future Perspectives. Health Evaluation and Promotion 2018; 45(3) doi: 10.7143/jhep.45.499
22
Işın Çakır, Pauline Lining Pan, Colleen K Hadley, Abdulrahman El-Gamal, Amina Fadel, Dina Elsayegh, Omnia Mohamed, Nasser M Rizk, Masoud Ghamari-Langroudi. Sulforaphane reduces obesity by reversing leptin resistance. eLife 2022; 11 doi: 10.7554/eLife.67368
23
Nabil M. Abdel-Hamid, Shimaa A. Abass, Ahmed A. Mohamed, Daniah Muneam Hamid. Herbal management of hepatocellular carcinoma through cutting the pathways of the common risk factors. Biomedicine & Pharmacotherapy 2018; 107 doi: 10.1016/j.biopha.2018.08.104
24
Ami Sotokawauchi, Yuji Ishibashi, Takanori Matsui, Sho-ichi Yamagishi, Yoshiji Ohta. Aqueous Extract of Glucoraphanin‐Rich Broccoli Sprouts Inhibits Formation of Advanced Glycation End Products and Attenuates Inflammatory Reactions in Endothelial Cells. Evidence-Based Complementary and Alternative Medicine 2018; 2018(1) doi: 10.1155/2018/9823141
25
Yoko Yagishita, Tonibelle N. Gatbonton-Schwager, Melissa L. McCallum, Thomas W. Kensler. Current Landscape of NRF2 Biomarkers in Clinical Trials. Antioxidants 2020; 9(8) doi: 10.3390/antiox9080716
26
Shohei Satomi, Shingo Takahashi, Kazutaka Yoshida, Sunao Shimizu, Takuro Inoue, Tsuyoshi Takara, Hiroyuki Suganuma. Effects of broccoli sprout supplements enriched in glucoraphanin on liver functions in healthy middle-aged adults with high-normal serum hepatic biomarkers: A randomized controlled trial. Frontiers in Nutrition 2022; 9 doi: 10.3389/fnut.2022.1077271
27
Zeinab Houshialsadat, Parvin Mirmiran, Ahmad Zare-Javid, Zahra Bahadoran, Christine Houghton. Beneficial Effects of Sulforaphane-Yielding Broccoli Sprout on Cardiometabolic Health: A Systematic Review and Meta-analysis. Jundishapur Journal of Natural Pharmaceutical Products 2022; 17(4) doi: 10.5812/jjnpp-129402
28
A.-M. Simundic, P. Filipi, A. Vrtaric, M. Miler, N. N. Gabaj, A. Kocsis, S. Avram, N. G. Barhanovic, A. Bulo, J. Cadamuro, E. Van. Dongen-Lases, P. Eker, A. Vital-e-Silva, E. Homsak, M. Ibarz, D. Labudovic, M. Nybo, H. Pivovarníková, I. Shmidt, J. Siodmiak, Z. Sumarac, D. Vitkus. Patient's knowledge and awareness about the effect of the over-the-counter (OTC) drugs and dietary supplements on laboratory test results: a survey in 18 European countries. Laboratornaya sluzhba 2020; 9(1) doi: 10.17116/labs2020901196
29
Davi Vieira Teixeira da Silva, Aline D’Avila Pereira, Gilson Teles Boaventura, Roberto Stefan de Almeida Ribeiro, Maurício Afonso Verícimo, Carla Eponina de Carvalho-Pinto, Diego dos Santos Baião, Eduardo Mere Del Aguila, Vania M. Flosi Paschoalin. Short-Term Betanin Intake Reduces Oxidative Stress in Wistar Rats. Nutrients 2019; 11(9) doi: 10.3390/nu11091978
30
Yi-kuan Wu, Zheng-nan Ren, Sheng-long Zhu, Yun-zhou Wu, Gang Wang, Hao Zhang, Wei Chen, Zhao He, Xian-long Ye, Qi-xiao Zhai. Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway. Acta Pharmacologica Sinica 2022; 43(6) doi: 10.1038/s41401-021-00786-2
31
Rui Nouchi, Qingqiang Hu, Yusuke Ushida, Hiroyuki Suganuma, Ryuta Kawashima. Effects of sulforaphane intake on processing speed and negative moods in healthy older adults: Evidence from a randomized controlled trial. Frontiers in Aging Neuroscience 2022; 14 doi: 10.3389/fnagi.2022.929628
32
Hiroki Sugiyama, Yukiko Kobayashi, Yoshio Sumida, Sayori Wada, Michiyo Tani, Yoshiaki Shizukawa, Koji Shirota, Yukiko Sasai, Taro Suzuki, Wataru Aoi, Yuji Naito, Masashi Kuwahata. A nutritional intervention that promotes increased vegetable intake in Japanese with non-alcoholic fatty liver disease: a six-month trial. Journal of Clinical Biochemistry and Nutrition 2022; 70(1) doi: 10.3164/jcbn.21-40
33
Annie G Langston-Cox, Sarah A Marshall, Kirsten R Palmer, Euan M Wallace. Prolong: a double-blind randomised placebo-controlled trial of broccoli sprout extract in women with early onset preeclampsia. A clinical trial protocol. BMJ Open 2019; 9(10) doi: 10.1136/bmjopen-2018-027493
34
Peng Lei, Sicong Tian, Chunying Teng, Lei Huang, Xiaodong Liu, Jiaojiao Wang, Yao Zhang, Baolong Li, Yujuan Shan. Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro. Molecular Nutrition & Food Research 2019; 63(4) doi: 10.1002/mnfr.201800795
35
Brandon E. Lung, Matthew Kim, Maddison McLellan, Kylie Callan, Edward D. Wang, William McMaster, Steven Yang, David H. So. Alkaline Phosphatase is an Independent Risk Factor for Periprosthetic Fractures in Total Joint Arthroplasty. JAAOS: Global Research and Reviews 2023; 7(2) doi: 10.5435/JAAOSGlobal-D-22-00129
36
Ana-Maria Simundic, Petra Filipi, Alen Vrtaric, Marijana Miler, Nora Nikolac Gabaj, Andrea Kocsis, Sanja Avram, Najdana Gligorovic Barhanovic, Anyla Bulo, Janne Cadamuro, Edmee van Dongen-Lases, Pinar Eker, Andre Vital-e-Silva, Evgenija Homsak, Mercedes Ibarz, Danica Labudovic, Mads Nybo, Hedviga Pivovarníková, Inna Shmidt, Joanna Siodmiak, Zorica Sumarac, Dalius Vitkus. Patient’s knowledge and awareness about the effect of the over-the-counter (OTC) drugs and dietary supplements on laboratory test results: a survey in 18 European countries. Clinical Chemistry and Laboratory Medicine (CCLM) 2018; 57(2) doi: 10.1515/cclm-2018-0579
37
Qingfeng He, Yunjing Luo, Ziqi Xie. Sulforaphane ameliorates cadmium induced hepatotoxicity through the up-regulation of /Nrf2/ARE pathway and the inactivation of NF-κB. Journal of Functional Foods 2021; 77 doi: 10.1016/j.jff.2020.104297
38
Jacopo Spezzini, Eugenia Piragine, Lorenzo Flori, Vincenzo Calderone, Alma Martelli. Natural H2S‐donors: A new pharmacological opportunity for the management of overweight and obesity. Phytotherapy Research 2024; 38(5) doi: 10.1002/ptr.8181
39
Bijal Patel, Giovanni E. Mann, Sarah J. Chapple. Concerted redox modulation by sulforaphane alleviates diabetes and cardiometabolic syndrome. Free Radical Biology and Medicine 2018; 122 doi: 10.1016/j.freeradbiomed.2018.02.004
40
Andrew Aussem, Kirsten Ludwig. The Potential for Reducing Lynch Syndrome Cancer Risk with Nutritional Nrf2 Activators. Nutrition and Cancer 2021; 73(3) doi: 10.1080/01635581.2020.1751215
41
Rafailia-Eirini Theodorou, Nikiforos Vrettos, Panagiotis Theodosis-Nobelos. From Supplements to Therapeutics: Repurposing Antioxidant Compounds in the Management of NAFLD (Non-Alcoholic Fatty Liver Disease). Applied Sciences 2026; 16(9) doi: 10.3390/app16094239
42
Hyeon Woo Sim, Won-Yong Lee, Ran Lee, Seo Young Yang, Youn-Kyung Ham, Sung Don Lim, Hyun-Jung Park. The Anti-Inflammatory Effects of Broccoli (Brassica oleracea L. var. italica) Sprout Extract in RAW 264.7 Macrophages and a Lipopolysaccharide-Induced Liver Injury Model. Current Issues in Molecular Biology 2023; 45(11) doi: 10.3390/cimb45110572
43
Inês Alves, Edilene Maria Queiroz Araújo, Louise T. Dalgaard, Sharda Singh, Elisabet Børsheim, Eugenia Carvalho. Protective Effects of Sulforaphane Preventing Inflammation and Oxidative Stress to Enhance Metabolic Health: A Narrative Review. Nutrients 2025; 17(3) doi: 10.3390/nu17030428
44
Montserrat Esteve. Mechanisms Underlying Biological Effects of Cruciferous Glucosinolate-Derived Isothiocyanates/Indoles: A Focus on Metabolic Syndrome. Frontiers in Nutrition 2020; 7 doi: 10.3389/fnut.2020.00111
45
Albena T. Dinkova-Kostova, Jed W. Fahey, Rumen V. Kostov, Thomas W. Kensler. KEAP1 and done? Targeting the NRF2 pathway with sulforaphane. Trends in Food Science & Technology 2017; 69 doi: 10.1016/j.tifs.2017.02.002
46
Dalia O. Saleh, Dina F. Mansour, Ingy M. Hashad, Rofanda M. Bakeer. Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway.. European Journal of Pharmacology 2019; 855 doi: 10.1016/j.ejphar.2019.04.043
47
Hail Kim, Sanghee Han, Minseo Oh, Hyun Woo Park, Jung Sun Kim, Seok-Geun Lee. High-glucosinolate Brassica rapa lines mitigate diet-induced hepatic steatosis through activation of the AMPK/SIRT1 and NRF2 pathways. Food Bioscience 2026; 78 doi: 10.1016/j.fbio.2026.108487
48
Mengjiao Wang, Min Chen, Rui Guo, Yangyang Ding, Haihui Zhang, Yuanqing He. The improvement of sulforaphane in type 2 diabetes mellitus (T2DM) and related complications: A review. Trends in Food Science & Technology 2022; 129 doi: 10.1016/j.tifs.2022.10.007
49
Suratsawadee Promsuwan, Kazuki Sawamoto, Liang Xu, Mayumi Nagashimada, Naoto Nagata, Yumi Takiyama. A natural Nrf2 activator glucoraphanin improves hepatic steatosis in high-fat diet-induced obese male mice associated with AMPK activation. Diabetology International 2024; 15(1) doi: 10.1007/s13340-023-00658-6
50
Ruheea Taskin Ruhee, Katsuhiko Suzuki. The Integrative Role of Sulforaphane in Preventing Inflammation, Oxidative Stress and Fatigue: A Review of a Potential Protective Phytochemical. Antioxidants 2020; 9(6) doi: 10.3390/antiox9060521
51
Mina Darand, Shahab Alizadeh, Marjan Mansourian. The effect of Brassica vegetables on blood glucose levels and lipid profiles in adults. A systematic review and meta‐analysis. Phytotherapy Research 2022; 36(5) doi: 10.1002/ptr.7410
52
Jia‑Wei Zhou, Min Wang, Nuan‑Xin Sun, Ying Qing, Teng‑Fei Yin, Cui Li, Dong Wu. Sulforaphane‑induced epigenetic regulation of Nrf2 expression by DNA methyltransferase in human Caco‑2 cells. Oncology Letters 2019;  doi: 10.3892/ol.2019.10569
53
Katie Treasure, James Harris, Gary Williamson. Exploring the anti‐inflammatory activity of sulforaphane. Immunology & Cell Biology 2023; 101(9) doi: 10.1111/imcb.12686
54
Koji Sato, Hinata Kihara, Yoka Kumazawa, Koki Tatara. Oral chronic sulforaphane effects on heavy resistance exercise: Implications for inflammatory and muscle damage parameters in young practitioners. Nutrition 2021; 90 doi: 10.1016/j.nut.2021.111266
55
Sunao Shimizu, Shuya Kasai, Chieko Suzuki, Tomoya Kon, Hiroyuki Suganuma, Shigenori Suzuki, Koichi Murashita, Shigeyuki Nakaji, Kazushige Ihara, Masahiko Tomiyama, Ken Itoh. Efficacy of 42-month oral administration of glucoraphanin in preventing cognitive decline in individuals at elevated risk of dementia, including those with mild cognitive impairment: a randomized, double-blind, placebo-controlled pilot study. Frontiers in Nutrition 2026; 13 doi: 10.3389/fnut.2026.1740494
56
Erika Ortega-Hernández, Marilena Antunes-Ricardo, Daniel A. Jacobo-Velázquez. Improving the Health-Benefits of Kales (Brassica oleracea L. var. acephala DC) through the Application of Controlled Abiotic Stresses: A Review. Plants 2021; 10(12) doi: 10.3390/plants10122629
57
Yong Yang, Akifumi Eguchi, Chisato Mori, Kenji Hashimoto. Dietary sulforaphane glucosinolate mitigates depression-like behaviors in mice with hepatic ischemia/reperfusion injury: A role of the gut–liver–brain axis. Journal of Psychiatric Research 2024; 176 doi: 10.1016/j.jpsychires.2024.06.005
58
Benito Soto-Blanco. Herbal Biomolecules in Healthcare Applications. 2022;  doi: 10.1016/B978-0-323-85852-6.00021-4
59
Liang Xu, Naoto Nagata, Tsuguhito Ota. Impact of Glucoraphanin-Mediated Activation of Nrf2 on Non-Alcoholic Fatty Liver Disease with a Focus on Mitochondrial Dysfunction. International Journal of Molecular Sciences 2019; 20(23) doi: 10.3390/ijms20235920
60
Richard I. Horowitz, John Fallon, Phyllis R. Freeman. Comparison of the Efficacy of Longer versus Shorter Pulsed High Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post Treatment Lyme Disease Syndrome with Bartonellosis and Associated Coinfections. Microorganisms 2023; 11(9) doi: 10.3390/microorganisms11092301
61
Jed W. Fahey, Hua Liu. Sulforaphane Synergies with Phytochemicals and Pharmaceuticals: Implications for Healthspan. Medicines 2026; 13(2) doi: 10.3390/medicines13020016
62
Jed W. Fahey, Thomas W. Kensler. The Challenges of Designing and Implementing Clinical Trials With Broccoli Sprouts… and Turning Evidence Into Public Health Action. Frontiers in Nutrition 2021; 8 doi: 10.3389/fnut.2021.648788
63
Anishma Karmacharya, Shiho Kasai, Yuuka Mukai, Shin Sato. Maternal Broccoli Powder Intake Ameliorates Insulin Resistance and Inflammation via AMPK/mTOR Pathway in the Livers of High‐Fructose‐Fed Male Rat Offspring Exposed to Maternal Protein Restriction. Molecular Nutrition & Food Research 2024; 68(22) doi: 10.1002/mnfr.202400472
64
Nicolas Monjotin, Marie Josèphe Amiot, Jacques Fleurentin, Jean Michel Morel, Sylvie Raynal. Clinical Evidence of the Benefits of Phytonutrients in Human Healthcare. Nutrients 2022; 14(9) doi: 10.3390/nu14091712
65
Takayuki Nabeshima, Manabu Tsukamoto, Ke-Yong Wang, Yosuke Mano, Daisuke Arakawa, Kenji Kosugi, Takafumi Tajima, Yoshiaki Yamanaka, Hitoshi Suzuki, Makoto Kawasaki, Soshi Uchida, Eiichiro Nakamura, Kagaku Azuma, Akinori Sakai. Delayed cortical bone healing due to impaired nuclear Nrf2 translocation in COPD mice. Bone 2023; 173 doi: 10.1016/j.bone.2023.116804
66
Edoardo Capuano, Matthijs Dekker, Ruud Verkerk, Teresa Oliviero. Food as Pharma? The Case of Glucosinolates. Current Pharmaceutical Design 2017; 23(19) doi: 10.2174/1381612823666170120160832
67
Sicong Tian, Yiting Lei, Fangling Zhao, Jiawen Che, Yanhong Wu, Peng Lei, Yea Eun Kang, Yujuan Shan. Improving insulin resistance by sulforaphane via activating the Bacteroides and Lactobacillus SCFAs–GPR–GLP1 signal axis. Food & Function 2024; 15(17) doi: 10.1039/D4FO01059K
68
Arun Rajgopal, SamanthaJ Roloff, CharlieR Burns, DavidJ Fast, JeffreyD Scholten. The cytoprotective benefits of a turmeric, quercetin, and rosemary blend through activation of the oxidative stress pathway. Pharmacognosy Magazine 2019; 15(66) doi: 10.4103/pm.pm_556_18
69
Babatunde Ogunlade, Sunday Adelakun, Kingsley Iteire. Sulforaphane response on aluminum-induced oxidative stress, alterations in sperm characterization and testicular histomorphometry in Wistar rats. International Journal of Reproductive BioMedicine (IJRM) 2020; 18(8) doi: 10.18502/ijrm.v13i8.7503
70
Jiaming Zhou, Qiuxian Zheng, Zhi Chen. The Nrf2 Pathway in Liver Diseases. Frontiers in Cell and Developmental Biology 2022; 10 doi: 10.3389/fcell.2022.826204
71
Liang Yan, Yachun Yan. Therapeutic potential of sulforaphane in liver diseases: a review. Frontiers in Pharmacology 2023; 14 doi: 10.3389/fphar.2023.1256029
72
Liang Xu, Naoto Nagata, Tsuguhito Ota. Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance. Adipocyte 2018; 7(3) doi: 10.1080/21623945.2018.1474669
73
Alessandra Ferramosca, Mariangela Di Giacomo, Vincenzo Zara. Antioxidant dietary approach in treatment of fatty liver: New insights and updates. World Journal of Gastroenterology 2017; 23(23): 4146-4157 doi: 10.3748/wjg.v23.i23.4146
74
Sunao Shimizu, Shuya Kasai, Hiromi Yamazaki, Yota Tatara, Junsei Mimura, Máté János Engler, Kunikazu Tanji, Yoshikazu Nikaido, Takuro Inoue, Hiroyuki Suganuma, Koichi Wakabayashi, Ken Itoh. Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice. International Journal of Molecular Sciences 2022; 23(15) doi: 10.3390/ijms23158433
75
Masahiro Kikuchi, Yudai Aoki, Noriaki Kishimoto, Yumi Masuda, Nana Suzuki, Shinji Takashimizu, Kazutaka Yoshida, Koichi Aizawa, Hiroyuki Suganuma, Yasuhiro Nishizaki. Effects of glucoraphanin-rich broccoli sprout extracts on sleep quality in healthy adults: An exploratory study. Journal of Functional Foods 2021; 84 doi: 10.1016/j.jff.2021.104574
76
Teresa Oliviero, Ruud Verkerk, Matthijs Dekker. Isothiocyanates fromBrassicaVegetables—Effects of Processing, Cooking, Mastication, and Digestion. Molecular Nutrition & Food Research 2018; 62(18) doi: 10.1002/mnfr.201701069
77
Tong-Xuan Tee, Li Ting Kee, Tsun-Thai Chai, Hok Chai Yam, Hasan Mahmud Reza, Fai-Chu Wong, Jia Xian Law, Sheri-Ann Tan. Plant-Derived Nrf2 Activators to Enhance Liver Antioxidative and Regenerative Potentials. Revista Brasileira de Farmacognosia 2024; 35(1) doi: 10.1007/s43450-024-00609-5
78
Rie Kurata, Tooru Kobayashi, Takanori Ishii, Hiroshi Niimi, Seiji Niisaka, Masaomi Kubo, Masaoki Kishimoto. Influence of Sweet Potato (<i>Ipomoea batatas</i> L.) Leaf Consumption on Rat Lipid Metabolism. Food Science and Technology Research 2017; 23(1) doi: 10.3136/fstr.23.57
79
Hiroki Sugiyama, Yukiko Kobayashi, Sayori Wada, Miho Ueda, Takatomo Shima, Taro Suzuki, Yoshio Sumida, Wataru Aoi, Yuji Naito, Masashi Kuwahata. An examination of eating behavior in patients with non-alcoholic fatty liver disease: A cross-sectional study in a Japanese population. Human Nutrition & Metabolism 2022; 28 doi: 10.1016/j.hnm.2022.200150
80
Bharti Mangla, Yub R Neupane, Archu Singh, Pankaj Kumar, Sadat Shafi, Kanchan Kohli. Lipid-Nanopotentiated Combinatorial Delivery of Tamoxifen and Sulforaphane: Ex Vivo , In Vivo and Toxicity Studies . Nanomedicine 2020; 15(26) doi: 10.2217/nnm-2020-0277
81
Seham S. Alqaraawi, Mona S. Almujaydil. Comparative assessment of Brassica nigra seed and its sprout ethanolic extracts against paracetamol-induced hepatotoxicity in rats: insight into antioxidant and anti-apoptotic pathways. Frontiers in Nutrition 2026; 13 doi: 10.3389/fnut.2026.1807243
82
Deepa S. Mandlik, Satish K. Mandlik. Herbal and Natural Dietary Products: Upcoming Therapeutic Approach for Prevention and Treatment of Hepatocellular Carcinoma. Nutrition and Cancer 2021; 73(11-12) doi: 10.1080/01635581.2020.1834591
83
Yoko Yagishita, Jed W. Fahey, Albena T. Dinkova-Kostova, Thomas W. Kensler. Broccoli or Sulforaphane: Is It the Source or Dose That Matters?. Molecules 2019; 24(19) doi: 10.3390/molecules24193593
84
Annie Langston-Cox, Sarah A. Marshall, Daisy Lu, Kirsten R. Palmer, Euan M. Wallace. Melatonin for the Management of Preeclampsia: A Review. Antioxidants 2021; 10(3) doi: 10.3390/antiox10030376
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