| For: | Fujita KI, Kubota Y, Ishida H, Sasaki Y. Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancer. World J Gastroenterol 2015; 21(43): 12234-12248 [PMID: 26604633 DOI: 10.3748/wjg.v21.i43.12234] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v21/i43/12234.htm |
| Number | Citing Articles |
| 1 |
Peng Zhu, Zhi Ye, Dong Guo, Zongping Xiong, Shiqiong Huang, Jun Guo, Wei Zhang, James E. Polli, Honghao Zhou, Qing Li, Yan Shu. Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2). Pharmaceutical Research 2018; 35(12) doi: 10.1007/s11095-018-2526-y
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| 2 |
A.L. Zakharenko, O.A. Luzina, D.N. Sokolov, V.I. Kaledin, V.P. Nikolin, N.A. Popova, J. Patel, O.D. Zakharova, A.A. Chepanova, A. Zafar, J. Reynisson, E. Leung, I.K.H. Leung, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik. Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models. European Journal of Medicinal Chemistry 2019; 161 doi: 10.1016/j.ejmech.2018.10.055
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| 3 |
Mônica F. Quintanilha, Vivian C. Miranda, Ramon O. Souza, Bruno Gallotti, Clênio Cruz, Elandia A. Santos, Jacqueline I. Alvarez-Leite, Luís C.L. Jesus, Vasco Azevedo, Luísa M. Trindade, Valbert N. Cardoso, Enio Ferreira, Bárbara A. Carvalho, Pedro M.G. Soares, Angélica T. Vieira, Jacques R. Nicoli, Flaviano S. Martins. Bifidobacterium longum subsp. longum 51A attenuates intestinal injury against irinotecan-induced mucositis in mice. Life Sciences 2022; 289 doi: 10.1016/j.lfs.2021.120243
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| 4 |
Trevor Ostlund, Faez Alotaibi, Jennifer Kyeremateng, Hossam Halaweish, Abigail Kasten, Surtaj Iram, Fathi Halaweish. Triazole-estradiol analogs: A potential cancer therapeutic targeting ovarian and colorectal cancer. Steroids 2022; 177 doi: 10.1016/j.steroids.2021.108950
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| 5 |
Izabela Rumienczyk, Maria Kulecka, Małgorzata Statkiewicz, Jerzy Ostrowski, Michal Mikula. Oncology Drug Repurposing for Sepsis Treatment. Biomedicines 2022; 10(4) doi: 10.3390/biomedicines10040921
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| 6 |
Haniye Rahimi Kolour, Nastaran Bahrami, Ehsan Nazemalhosseini-Mojarad, Amir Sadeghi, Mehdi Shamsara, Nayeralsadat Fatemi. Metformin’s multifaceted role in colorectal cancer: mechanisms of action and synergy with standard treatments. Discover Oncology 2025; 16(1) doi: 10.1007/s12672-025-03905-1
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| 7 |
Mohammed Hadi Ali Al-Jumaili, Ekhlas Aziz Bakr, Mohanad A. Huessien, Ahmed Solaiman Hamed, Mohammed J. Muhaidi. Development of heterocyclic-based anticancer agents: A comprehensive review. Heterocyclic Communications 2025; 31(1) doi: 10.1515/hc-2022-0179
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| 8 |
Stefanie Ho Yi Chan, Raymond W. Fitzpatrick, Deborah Layton, Sherael Webley, Sam Salek. Cancer Therapy-Induced Cardiotoxicity: Results of the Analysis of the UK DEFINE Database. Cancers 2025; 17(2) doi: 10.3390/cancers17020311
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| 9 |
Qiongna Dong, Bizhi Shi, Min Zhou, Huiping Gao, Xiaoying Luo, Zonghai Li, Hua Jiang. Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12. Frontiers of Medicine 2019; 13(1) doi: 10.1007/s11684-019-0682-z
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| 10 |
Ram P. Das, Sarjak Chakravarti, Snehal S. Patel, Pooja Lakhamje, Murari Gurjar, Vikram Gota, Beena G. Singh, Amit Kunwar. Tuning the pharmacokinetics and efficacy of irinotecan (IRI) loaded gelatin nanoparticles through folate conjugation. International Journal of Pharmaceutics 2020; 586 doi: 10.1016/j.ijpharm.2020.119522
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| 11 |
Rossella Salemi, Silvia Vivarelli, Daria Ricci, Marina Scillato, Maria Santagati, Giuseppe Gattuso, Luca Falzone, Massimo Libra. Lactobacillus rhamnosus GG cell-free supernatant as a novel anti-cancer adjuvant. Journal of Translational Medicine 2023; 21(1) doi: 10.1186/s12967-023-04036-3
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| 12 |
Dalong Wang, Tingting Zhao, Shan Zhao, Jing Chen, Tongyi Dou, Guangbo Ge, Changyuan Wang, Huijun Sun, Kexin Liu, Qiang Meng, Jingjing Wu. Substrate-dependent Inhibition of Hypericin on Human Carboxylesterase 2: Implications
for Herb-drug Combination. Current Drug Metabolism 2022; 23(1) doi: 10.2174/1389200223666220202093303
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| 13 |
Brandon N. VanderVeen, Thomas D. Cardaci, Brooke M. Bullard, Christian A. Unger, Jeffrey C. Freeman, Reilly T. Enos, Michael Shtutman, Michael D. Wyatt, Daping Fan, E. Angela Murphy. The impact of diet-induced obesity on 5 fluorouracil-induced tumor and liver immune cell cytotoxicity. American Journal of Physiology-Cell Physiology 2025; 328(1) doi: 10.1152/ajpcell.00687.2024
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| 14 |
Santosh Kumar, Michael Y. Sherman. Resistance to TOP-1 Inhibitors: Good Old Drugs Still Can Surprise Us. International Journal of Molecular Sciences 2023; 24(8) doi: 10.3390/ijms24087233
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| 15 |
Erika Cecchin, Elena De Mattia, Fabrizio Ecca, Giuseppe Toffoli. Host genetic profiling to increase drug safety in colorectal cancer from discovery to implementation. Drug Resistance Updates 2018; 39 doi: 10.1016/j.drup.2018.07.001
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| 16 |
Eman E. Nasr, Amany S. Mostafa, Magda A. A. El‐Sayed, Mohammed A. M. Massoud. Design, synthesis, and docking study of new quinoline derivatives as antitumor agents. Archiv der Pharmazie 2019; 352(7) doi: 10.1002/ardp.201800355
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| 17 |
E. Samalin, L. Evesque, A. Turpin, C. De La Fouchardiere, F. Khemissa-Akouz, O. Bouché, M. Muller, S. Dermeche, D. Botsen, D. Tougeron, A. Zaanan, M. Ben Abdelghani, E. Guardiola, O. Dubreuil, V. Le Brun Ly, A. Hennequin, S. Watson, D. Sefrioui, T. Lecomte, N. De Sousa Carvalho, A. Hulin, E. Crapez, F. Castan, H. Senellart. Regorafenib combined with irinotecan as second-line treatment in metastatic gastro-oesophageal adenocarcinomas: results of PRODIGE 58–UCGI35–REGIRI Unicancer randomised phase II study. ESMO Open 2025; 10(5) doi: 10.1016/j.esmoop.2025.105096
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| 18 |
Zuzanna Kobus, Anita Karimi, Hooman Yarmohammadi. Transarterial Therapy for Liver Tumors. Hematology/Oncology Clinics of North America 2026; doi: 10.1016/j.hoc.2026.05.007
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| 19 |
Benedikt Seligmann, Shenyu Liu, Mai Huynh, Thu-Thuy T. Dang, Jakob Franke. Production of the anticancer drug intermediate strictosidinic acid in engineered yeast. Journal of Biotechnology 2026; 415 doi: 10.1016/j.jbiotec.2026.03.017
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| 20 |
Karishma Kailass, Alexandra F. Tassielli, Ruifan Dai, Francisca Beato, Bhaswati Sarcar, Jennifer Permuth, Margaret Park, Jason B. Fleming, Andrew A. Beharry. Ratiometric Fluorescent Chemosensing for Predicting Response to Irinotecan-Based Therapies in Pancreatic Ductal Adenocarcinoma. ACS Sensors 2026; 11(5) doi: 10.1021/acssensors.5c04552
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| 21 |
Dylan T. Marsh, Scott D. Smid. Selected phytocannabinoids inhibit SN-38- and cytokine-evoked increases in epithelial permeability and improve intestinal barrier function in vitro. Toxicology in Vitro 2024; 99 doi: 10.1016/j.tiv.2024.105888
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| 22 |
Shuqin Xing, Yafei Wang, Kaiwen Hu, Fen Wang, Tao Sun, Quanwang Li. WGCNA reveals key gene modules regulated by the combined treatment of colon cancer with PHY906 and CPT11. Bioscience Reports 2020; 40(9) doi: 10.1042/BSR20200935
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| 23 |
Nikolaos Tsakiris, Malamatenia Papavasileiou, Elia Bozzato, Alessandra Lopes, Arnaud M. Vigneron, Véronique Préat. Combinational drug-loaded lipid nanocapsules for the treatment of cancer. International Journal of Pharmaceutics 2019; 569 doi: 10.1016/j.ijpharm.2019.118588
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| 24 |
Thaise Boeing, Priscila de Souza, Silvia Speca, Lincon Bordignon Somensi, Luisa Nathália Bolda Mariano, Benhur Judah Cury, Mariana Ferreira dos Anjos, Nara Lins Meira Quintão, Laurent Dubuqoy, Pierre Desreumax, Luisa Mota da Silva, Sérgio Faloni de Andrade. Luteolin prevents irinotecan‐induced intestinal mucositis in mice through antioxidant and anti‐inflammatory properties. British Journal of Pharmacology 2020; 177(10) doi: 10.1111/bph.14987
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| 25 |
Anne Kauffels, Hannah Nowack, Hanibal Bohnenberger, Melanie Spitzner, Thilo Sprenger, Michael Ghadimi, Jens Sperling. Hepatic arterial infusion with nanoliposomal irinotecan leads to significant regression of tumor size of colorectal liver metastases in a CC531 rat model. Clinical & Experimental Metastasis 2023; 40(3) doi: 10.1007/s10585-023-10209-7
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| 26 |
Neetu Saini, Monika Kadian, Anil Kumar. Biomarkers in Cancer Detection and Monitoring of Therapeutics. 2024; doi: 10.1016/B978-0-323-95116-6.00006-2
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| 27 |
Karishma Kailass, Oleg Sadovski, Warren R. Zipfel, Andrew A. Beharry. Two-Photon Photodynamic Therapy Targeting Cancers with Low Carboxylesterase 2 Activity Guided by Ratiometric Fluorescence. Journal of Medicinal Chemistry 2022; 65(13) doi: 10.1021/acs.jmedchem.1c01965
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| 28 |
Prasanna Anjaneyulu Yakkala, Naveen Reddy Penumallu, Syed Shafi, Ahmed Kamal. Prospects of Topoisomerase Inhibitors as Promising Anti-Cancer Agents. Pharmaceuticals 2023; 16(10) doi: 10.3390/ph16101456
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| 29 |
Takashi Higuchi, Kentaro Miyake, Hiromichi Oshiro, Norihiko Sugisawa, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Sant P. Chawla, Michael Bouvet, Shree Ram Singh, Hiroyuki Tsuchiya, Robert M. Hoffman. Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model. Biochemical and Biophysical Research Communications 2019; 513(2) doi: 10.1016/j.bbrc.2019.03.191
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| 30 |
Saurav Kumar Mishra, Tabsum Chhetri, Sneha Roy, Aamal A. Al-Mutairi, Adino Asmare Aragaw, Emad Rashad Sindi, Magdi E. A. Zaki, John J. Georrge. Decoding cross-talk between Mpox and HIV: insights from transcriptomics and network-based analyses. Virology Journal 2025; 23(1) doi: 10.1186/s12985-025-03026-9
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| 31 |
Iera Hernandez-Unzueta, Aitor Benedicto, Elvira Olaso, Eduardo Sanz, Cristina Viera, Beatriz Arteta, Joana Márquez. Ocoxin oral solution® as a complement to irinotecan chemotherapy in the metastatic progression of colorectal cancer to the liver. Oncology Letters 2017; 13(6) doi: 10.3892/ol.2017.6016
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| 32 |
Jiali Dai, Yuetong Chen, Yang Gong, Jingsun Wei, Xiaowen Cui, Hualin Yu, Wenjing Zhao, Dongying Gu, Jinfei Chen. The efficacy and safety of irinotecan ± bevacizumab compared with oxaliplatin ± bevacizumab for metastatic colorectal cancer. Medicine 2019; 98(39) doi: 10.1097/MD.0000000000017384
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| 33 |
Muttiah Barathan, Ahmad Khusairy Zulpa, Sook Luan Ng, Yogeswaran Lokanathan, Min Hwei Ng, Jia Xian Law. Innovative Strategies to Combat 5-Fluorouracil Resistance in Colorectal Cancer: The Role of Phytochemicals and Extracellular Vesicles. International Journal of Molecular Sciences 2024; 25(13) doi: 10.3390/ijms25137470
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| 34 |
Justin C. Merritt, Stephen D. Richbart, Emily G. Moles, Ashley J. Cox, Kathleen C. Brown, Sarah L. Miles, Paul T. Finch, Joshua A. Hess, Maria T. Tirona, Monica A. Valentovic, Piyali Dasgupta. Anti-cancer activity of sustained release capsaicin formulations. Pharmacology & Therapeutics 2022; 238 doi: 10.1016/j.pharmthera.2022.108177
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| 35 |
Chonghui Liu, Yan Zhang, Yingjian Liang, Tianjiao Zhang, Guohua Wang. DrugReSC: targeting disease-critical cell subpopulations with single-cell transcriptomic data for drug repurposing in cancer. Briefings in Bioinformatics 2024; 25(6) doi: 10.1093/bib/bbae490
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| 36 |
Enpeng Xi, Yue Zhao, Huan Wang, Yun Zhao, Fangfang Cao, Yue Li, Nan Gao. Customized porous aromatic frameworks (PAFs) as an oral antidote for efficient and selective intestinal detoxification. Nanoscale Horizons 2026; 11(6) doi: 10.1039/D5NH00784D
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| 37 |
Elena De Mattia, Erika Cecchin, Marcella Montico, Adrien Labriet, Chantal Guillemette, Eva Dreussi, Rossana Roncato, Alessia Bignucolo, Angela Buonadonna, Mario D’Andrea, Luigi Coppola, Sara Lonardi, Eric Lévesque, Derek Jonker, Félix Couture, Giuseppe Toffoli. Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients. Frontiers in Pharmacology 2018; 9 doi: 10.3389/fphar.2018.00367
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| 38 |
Vinod K. Nelson, Mohana Vamsi Nuli, Juturu Mastanaiah, Mohamed Saleem T. S., Geetha Birudala, Yahya F. Jamous, Omar Alshargi, Kranthi Kumar Kotha, Hari Hara Sudhan, Ravishankar Ram Mani, Alagusundaram Muthumanickam, Divya Niranjan, Nem Kumar Jain, Ankur Agrawal, Arvind Singh Jadon, Vinyas Mayasa, Niraj Kumar Jha, Adriana Kolesarova, Petr Slama, Shubhadeep Roychoudhury. Reactive oxygen species mediated apoptotic death of colon cancer cells: therapeutic potential of plant derived alkaloids. Frontiers in Endocrinology 2023; 14 doi: 10.3389/fendo.2023.1201198
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| 39 |
Yifeng Qin, An Kang, Guisheng Zhou, Huan Wang, Wei Wei, Yujie Cao, Yanyan Chen, Jing Wang, Yajun Shi, Yuping Tang, Jianqin Jiang. Carboxylesterase and UDP‐glucuronosyltransferases mediated metabolism of irinotecan: In vitro and in vivo insights from quantitative ultra‐performance liquid chromatography–mass spectrometry analysis. Biomedical Chromatography 2018; 32(10) doi: 10.1002/bmc.4320
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| 40 |
Monika Berbecka, Alicja Forma, Jacek Baj, Marzena Furtak-Niczyporuk, Ryszard Maciejewski, Robert Sitarz. A Systematic Review of the Cyclooxygenase-2 (COX-2) Expression in Rectal Cancer Patients Treated with Preoperative Radiotherapy or Radiochemotherapy. Journal of Clinical Medicine 2021; 10(19) doi: 10.3390/jcm10194443
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| 41 |
Mihin Targu, Bishal Pun, Mamta Arora, Santa Ram Joshi, Suman Kumaria. Evaluation of bioactive compounds, antioxidant and antimicrobial properties of Bulbophyllum griffithii (Lindl.) Rchb.f., an unexplored rare orchid of therapeutic importance. South African Journal of Botany 2024; 174 doi: 10.1016/j.sajb.2024.08.049
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| 42 |
Velko Minchev, Hristo Tsankov, Bozil Robev, Martin Takov, Stefan Federchev, Kalina Kamenova, Lozan Todorov, Liliya Atanasova, Nadya Hristova-Avakumova, Rumen Nikolov, Pavlina Gateva, Vanyo Mitev. Gastrointestinal Cancers with Consideration of DPD and UGT1A1 Plasma Levels: Chemotherapy-Related Toxicity. Life 2025; 15(7) doi: 10.3390/life15071071
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| 43 |
Zongqiang Wang, Amanda Kasper, Mai Takahashi, Adrian Morales Amador, Abir Bhattacharjee, Jingbo Kan, Yozen Hernandez, Melinda Ternei, Sean F. Brady. Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn‐BNP)‐Coupled Metagenomics. Angewandte Chemie 2024; 136(17) doi: 10.1002/ange.202317187
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| 44 |
Reetu Mukherji, John Marshall, Andreas Seeber. Genomic Alterations and Their Implications on Survival in Nonmetastatic Colorectal Cancer: Status Quo and Future Perspectives. Cancers 2020; 12(8) doi: 10.3390/cancers12082001
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| 45 |
Jasmine Chaudhary, Akash Jain, Garima Malik. Polymer-Drug Conjugates. 2023; doi: 10.1016/B978-0-323-91663-9.00001-1
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| 46 |
Huafeng Jiang, Senjun Zhou, Gang Li. Novel biomarkers used for early diagnosis and tyrosine kinase inhibitors as targeted therapies in colorectal cancer. Frontiers in Pharmacology 2023; 14 doi: 10.3389/fphar.2023.1189799
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| 47 |
Claire Andre, Lydie Lethier, Yves Claude Guillaume. Long term and simulated in-use stabilities of irinotecan chemotherapy polyolefin infusion bags in dose banding conditions. Journal of Oncology Pharmacy Practice 2025; doi: 10.1177/10781552251338763
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| 48 |
Sergio C. Chai, William C. Wright, Taosheng Chen. Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer. Medicinal Research Reviews 2020; 40(3) doi: 10.1002/med.21648
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| 49 |
Yong-Hee Cho, Eun Ji Ro, Jeong-Su Yoon, Tomohiro Mizutani, Dong-Woo Kang, Jong-Chan Park, Tae Il Kim, Hans Clevers, Kang-Yell Choi. 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation. Nature Communications 2020; 11(1) doi: 10.1038/s41467-020-19173-2
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| 50 |
"Cholinergic side Effect-Free anticancer drugs: paving the way for safer and more effective cancer treatment". Journal of Biomolecular Structure and Dynamics 2024; 42(23) doi: 10.1080/07391102.2023.2274968
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| 51 |
Isabella Lo, Sanika Vaidya, Ashley Mo, Alyssa Yee-Xin Chia, Katelyn Li, Jessica Parvin, Sripathy Sadagopan, Zane D’souza, Olivia Kwok, Jenny Zhang, Isa Baratoff, Shreya Somani, Lekhya Menta, Yining Xie, Thomas Sanchez, Terry Wang, Rebecca Chen, Akira Yamamoto, Joseph Pazzi, Edward Njoo. Blue Fluorescent Siloxytecans Exhibit Potent Anticancer Activity and Enable Direct Real-Time Quantification of Intracellular Uptake. ACS Bio & Med Chem Au 2026; 6(1) doi: 10.1021/acsbiomedchemau.5c00155
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| 52 |
Bashdar Mahmud Hussen, Snur Rasool Abdullah, Abdulqahar Azizkhan Mohammed, Mohammed Fatih Rasul, Ali M. Hussein, Solat Eslami, Mark C. Glassy, Mohammad Taheri. Advanced strategies of targeting circular RNAs as therapeutic approaches in colorectal cancer drug resistance. Pathology - Research and Practice 2024; 260 doi: 10.1016/j.prp.2024.155402
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| 53 |
Maria M. Lukina, Marina A. Sirotkina, Anna G. Orlova, Varvara V. Dudenkova, Anastasia D. Komarova, Anton A. Plekhanov, Ludmila B. Snopova, Elena V. Zagaynova, Dmitri B. Papkovsky, Vladislav I. Shcheslavskiy, Marina V. Shirmanova. Effects of Irinotecan on Tumor Vasculature and Oxygenation: An in vivo Study on Colorectal Cancer Model. IEEE Journal of Selected Topics in Quantum Electronics 2021; 27(4) doi: 10.1109/JSTQE.2020.3047518
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| 54 |
Armel J. Seukep, Victor Kuete. African plant-based products as a source of potent drugs to overcome cancers and their chemoresistance Part 1. Cancer chemoresistance, screening methods, and the updated cut-off points for the classification of natural cytotoxic products. Advances in Botanical Research 2024; 111 doi: 10.1016/bs.abr.2023.12.001
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| 55 |
Rick-Léonid Ngoua Meye Misso, Fleury Augustin Nsole Biteghe, Cédric Sima Obiang, Joseph-Privat Ondo, Nan Gao, Miguel Cervantes-Cervantes, Guillaume Vignaux, Aurelia Vergeade, Jean Engohang-Ndong, Hugue Ella Mendene, Barthelemy Mabika, Félix Ovono Abessolo, Louis-Clement Obame Engonga, Jean De La Croix Ndong. Effect of aqueous extracts of Ficus vogeliana Miq and Tieghemella africana Pierre in 7,12-Dimethylbenz(a)anthracene -induced skin cancer in rats. Journal of Ethnopharmacology 2020; 263 doi: 10.1016/j.jep.2020.113244
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| 56 |
Ruipu Sun, Ying Ying, Zhimin Tang, Ting Liu, Fuli Shi, Huixia Li, Taichen Guo, Shibo Huang, Ren Lai. The Emerging Role of the SLCO1B3 Protein in Cancer Resistance. Protein & Peptide Letters 2019; 27(1) doi: 10.2174/0929866526666190926154248
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| 57 |
Tahia K. Mohamed, Rasha Z. Batran, Samia A. Elseginy, Mamdouh M. Ali, Abeer E. Mahmoud. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis. Bioorganic Chemistry 2019; 85 doi: 10.1016/j.bioorg.2018.12.040
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| 58 |
Jing-Fang Zhang, Wan-Chao Zhong, Yan-Cheng Li, Yun-Qing Song, Gui-Yang Xia, Gui-Hua Tian, Guang-Bo Ge, Sheng Lin. Bioactivity-Guided Discovery of Human Carboxylesterase Inhibitors from the Roots of Paeonia lactiflora. Journal of Natural Products 2020; 83(10) doi: 10.1021/acs.jnatprod.0c00464
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| 59 |
Chahat suri, Babita Pande, Lakkakula Suhani Sahithi, Shashikant Swarnkar, Tuneer Khelkar, Henu Kumar Verma. Metabolic crossroads: unravelling immune cell dynamics in gastrointestinal cancer drug resistance. Cancer Drug Resistance 2025; doi: 10.20517/cdr.2024.164
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| 60 |
Xian Zhao, Ruijie Xu, Yuanyuan Zhai, Yi Wang, Yuxin Zhang, Yuan Tian, Fengguo Xu, Pei Zhang. Liposomal Vardenafil and Linagliptin Combined with Irinotecan for Synergistic Colorectal Cancer Therapy. Pharmaceutical Research 2025; 42(6) doi: 10.1007/s11095-025-03876-6
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| 61 |
Katy Vaillancourt, Amel Ben Lagha, Daniel Grenier. A green tea extract and epigallocatechin-3-gallate attenuate the deleterious effects of irinotecan in an oral epithelial cell model. Archives of Oral Biology 2021; 126 doi: 10.1016/j.archoralbio.2021.105135
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| 62 |
Jia‐Nan Li, Yun‐Feng Cao, Rong‐Rong He, Guang‐Bo Ge, Bin Guo, Jing‐Jing Wu. Evidence for Shikonin acting as an active inhibitor of human carboxylesterases 2: Implications for herb–drug combination. Phytotherapy Research 2018; 32(7) doi: 10.1002/ptr.6062
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| 63 |
Anne Kauffels, Marie Kitzmüller, Andrea Gruber, Hannah Nowack, Hanibal Bohnenberger, Melanie Spitzner, Anja Kuthning, Thilo Sprenger, Martin Czejka, Michael Ghadimi, Jens Sperling. Hepatic arterial infusion of irinotecan and EmboCept® S results in high tumor concentration of SN-38 in a rat model of colorectal liver metastases. Clinical & Experimental Metastasis 2019; 36(1) doi: 10.1007/s10585-019-09954-5
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| 64 |
Darren C. Phillips, Fritz G. Buchanan, Dong Cheng, Larry R. Solomon, Yu Xiao, John Xue, Stephen K. Tahir, Morey L. Smith, Haichao Zhang, Deborah Widomski, Vivek C. Abraham, Nan Xu, Zhihong Liu, Li Zhou, Enrico DiGiammarino, Xin Lu, Nandini Rudra-Ganguly, Bruce Trela, Susan E. Morgan-Lappe. Hexavalent TRAIL Fusion Protein Eftozanermin Alfa Optimally Clusters Apoptosis-Inducing TRAIL Receptors to Induce On-Target Antitumor Activity in Solid Tumors. Cancer Research 2021; 81(12) doi: 10.1158/0008-5472.CAN-20-2178
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| 65 |
Jonathan P. Evans, Boleslaw K. Winiarski, Paul A. Sutton, Robert P. Jones, Lorenzo Ressel, Carrie A. Duckworth, D. Mark Pritchard, Zhi-Xiu Lin, Vicky L. Fretwell, Elizabeth M. Tweedle, Eithne Costello, Christopher E. Goldring, Ian M. Copple, B. Kevin Park, Daniel H. Palmer, Neil R. Kitteringham. The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer. Oncotarget 2018; 9(43) doi: 10.18632/oncotarget.25497
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| 66 |
Thaise Boeing, Marcelo Biondaro Gois, Priscila de Souza, Lincon Bordignon Somensi, Débora de Mello Gonçales Sant´Ana, Luisa Mota da Silva. Irinotecan-induced intestinal mucositis in mice: a histopathological study. Cancer Chemotherapy and Pharmacology 2021; 87(3) doi: 10.1007/s00280-020-04186-x
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| 67 |
Takeshi Kinoshita, Hajime Higuchi, Ayano- Kabashima-, Gen Sakai, Yasuo Hamamoto, Hiromasa Takaishi, Takanori Kanai. Analysis of Sensitivity and Cell Death Pathways Mediated by Anti-cancer Drugs Using Three-dimensional Culture System. International Journal of Cancer Research 2017; 14(1) doi: 10.3923/ijcr.2018.1.12
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| 68 |
Mateusz Kciuk, Beata Marciniak, Renata Kontek. Irinotecan—Still an Important Player in Cancer Chemotherapy: A Comprehensive Overview. International Journal of Molecular Sciences 2020; 21(14) doi: 10.3390/ijms21144919
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| 69 |
Carolina De la Guardia, David Stephens, Hang Dang, Mario Quijada, Oleg Larionov, Ricardo Lleonart. Antiviral Activity of Novel Quinoline Derivatives against Dengue Virus Serotype 2. Molecules 2018; 23(3) doi: 10.3390/molecules23030672
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| 70 |
Deysi Viviana Tenazoa Wong, Renata Brito Falcão Holanda, Aurilene Gomes Cajado, Alessandro Maia Bandeira, Jorge Fernando Bessa Pereira, Joice Oliveira Amorim, Clarice Sampaio Torres, Luana Maria Moura Ferreira, Marina Helena Silva Lopes, Roberta Taiane Germano Oliveira, Anamaria Falcão Pereira, Rosane Oliveira Sant'Ana, Larissa Mont'alverne Arruda, Howard Lopes Ribeiro‐Júnior, Ronald Feitosa Pinheiro, Paulo Roberto Carvalho Almeida, Robson Francisco Carvalho, Fábio Figueiredo Chaves, Duílio Reis Rocha‐Filho, Fernando Queiroz Cunha, Roberto César Pereira Lima‐Júnior. TLR4 deficiency upregulates TLR9 expression and enhances irinotecan‐related intestinal mucositis and late‐onset diarrhoea. British Journal of Pharmacology 2021; 178(20) doi: 10.1111/bph.15609
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| 71 |
Satoru Sasagawa, Jun Kumai, Toru Wakamatsu, Yoshihiro Yui. Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma. Cancer Innovation 2024; 3(2) doi: 10.1002/cai2.113
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| 72 |
Sushobhan Chowdhury, Manisha Parlewar, Dheeraj Kashyap, Prerna Mahajan, Ranbeer Malhotra, Utkarsh Chauhan, Abhinav Parindiyal. Development of machine learning models for the precise identification of potential molecules active against pancreatic Cancer. Results in Chemistry 2026; 27 doi: 10.1016/j.rechem.2026.103425
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