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For: Lin D, Wu J. Hypoxia inducible factor in hepatocellular carcinoma: A therapeutic target. World J Gastroenterol 2015; 21(42): 12171-12178 [PMID: 26576101 DOI: 10.3748/wjg.v21.i42.12171]
URL: https://www.wjgnet.com/1007-9327/full/v21/i42/12171.htm
Number Citing Articles
1
Stavros P. Papadakos, Ioanna E. Stergiou, Nikolina Gkolemi, Konstantinos Arvanitakis, Stamatios Theocharis. Unraveling the Significance of EPH/Ephrin Signaling in Liver Cancer: Insights into Tumor Progression and Therapeutic ImplicationsCancers 2023; 15(13): 3434 doi: 10.3390/cancers15133434
2
Weiwei Hu, Shufang Zheng, Haixin Guo, Beiying Dai, Jiaping Ni, Yaohong Shi, Hanrui Bian, Lanxin Li, Yumeng Shen, Mo Wu, Zhoutong Tian, Guilai Liu, Md Amir Hossain, Hongbao Yang, Duowei Wang, Qin Zhang, Jun Yu, Lutz Birnbaumer, Jifeng Feng, Decai Yu, Yong Yang. PLAGL2‐EGFR‐HIF‐1/2α Signaling Loop Promotes HCC Progression and Erlotinib InsensitivityHepatology 2021; 73(2): 674 doi: 10.1002/hep.31293
3
Takayuki Shimizu, Taku Aoki, Shozo Mori, Yukihiro Iso, Masato Kato, Mitsuru Ishizuka, Keiichi Kubota. Tumor DNA-dependent protein kinase catalytic subunit expression is associated with hepatitis B surface antigen status and tumor progression in patients with hepatocellular carcinomaScientific Reports 2018; 8(1) doi: 10.1038/s41598-018-33427-6
4
Carolina Méndez-Blanco, Flavia Fondevila, Andrés García-Palomo, Javier González-Gallego, José L. Mauriz. Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factorsExperimental & Molecular Medicine 2018; 50(10): 1 doi: 10.1038/s12276-018-0159-1
5
Weiguo Hong, Yan Hu, Zhenping Fan, Rong Gao, Ruichuang Yang, Jingfeng Bi, Jun Hou. In silico identification of EP400 and TIA1 as critical transcription factors involved in human hepatocellular carcinoma relapseOncology Letters 2019;  doi: 10.3892/ol.2019.11171
6
Zhiqiang Chen, Xueliang Zuo, Yao Zhang, Guoyong Han, Long Zhang, Jindao Wu, Xuehao Wang. MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1α-mediated Warburg effectCell Death & Disease 2018; 9(5) doi: 10.1038/s41419-018-0616-8
7
Hui-xing Zhang, You Kang, Ning Li, Hai-feng Wang, Yong-rui Bao, Yan-wu Li, Xue-zheng Li, Zhe Jiang, Gang Chen. Triterpenoids from Liquidambar Fructus induced cell apoptosis via a PI3K-AKT related signal pathway in SMMC7721 cancer cellsPhytochemistry 2020; 171: 112228 doi: 10.1016/j.phytochem.2019.112228
8
Liangfang Yao, Yang Xuan, Haiyang Zhang, Bo Yang, Xinglong Ma, Tianzhen Wang, Tianyuan Meng, Wenshe Sun, Haibin Wei, Xueqing Ma, Robb Moses, Jianru Xiao, Pei Zhang, Chao Ge, Jinjun Li, Lei Li, Xiaotao Li, Jinbao Li, Bianhong Zhang. Reciprocal REGγ-mTORC1 regulation promotes glycolytic metabolism in hepatocellular carcinomaOncogene 2021; 40(3): 677 doi: 10.1038/s41388-020-01558-8
9
Eloi R Verrier, Amélie Weiss, Charlotte Bach, Laura Heydmann, Vincent Turon-Lagot, Arnaud Kopp, Houssein El Saghire, Emilie Crouchet, Patrick Pessaux, Thomas Garcia, Patrick Pale, Mirjam B Zeisel, Camille Sureau, Catherine Schuster, Laurent Brino, Thomas F Baumert. Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targetsGut 2020; 69(1): 158 doi: 10.1136/gutjnl-2018-317065
10
Kurt Sartorius, Samuel O. Antwi, Anil Chuturgoon, Lewis R. Roberts, Anna Kramvis. RNA Therapeutic Options to Manage Aberrant Signaling Pathways in Hepatocellular Carcinoma: Dream or Reality?Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.891812
11
Bin Zhu, Shaoying Pan, Juanjuan Liu, Suli Wang, Ying Ni, Linlin Xiao, Quhao Wei, You Peng, Zhiyong Ding, Wenli Zhao. HIF‐1α forms regulatory loop with YAP to coordinate hypoxia‐induced adriamycin resistance in acute myeloid leukemia cellsCell Biology International 2020; 44(2): 456 doi: 10.1002/cbin.11246
12
Zhan-Jun Ma, Xue-Xi Wang, Gang Su, Jing-Jing Yang, Ya-Juan Zhu, You-Wei Wu, Jing Li, Li Lu, Long Zeng, Hai-Xia Pei. Proteomic analysis of apoptosis induction by lariciresinol in human HepG2 cellsChemico-Biological Interactions 2016; 256: 209 doi: 10.1016/j.cbi.2016.07.011
13
Xiaomeng Dai, Guoliang Pi, Sheng-li Yang, George G. Chen, Li-ping Liu, Han-Hua Dong. Association of PD-L1 and HIF-1α Coexpression with Poor Prognosis in Hepatocellular CarcinomaTranslational Oncology 2018; 11(2): 559 doi: 10.1016/j.tranon.2018.02.014
14
Fei Jia, Baolin Wu, Ruifang Yan, Lei Li, Kaiyu Wang, Dongming Han. Prediction Model for Intermediate‐Stage Hepatocellular Carcinoma Response to Transarterial ChemoembolizationJournal of Magnetic Resonance Imaging 2020; 52(6): 1657 doi: 10.1002/jmri.27189
15
Sha Fu, Rong-rong Zhou, Ning Li, Yan Huang, Xue-Gong Fan. Hepatitis B virus X protein in liver tumor microenvironmentTumor Biology 2016; 37(12): 15371 doi: 10.1007/s13277-016-5406-2
16
Yongdong Liu, Liling Sun, Xingwang Su, Sien Guo. Inhibition of eukaryotic initiation factor 4E phosphorylation by cercosporamide selectively suppresses angiogenesis, growth and survival of human hepatocellular carcinomaBiomedicine & Pharmacotherapy 2016; 84: 237 doi: 10.1016/j.biopha.2016.09.038
17
Zahra Farzaneh, Massoud Vosough, Tarun Agarwal, Maryam Farzaneh. Critical signaling pathways governing hepatocellular carcinoma behavior; small molecule-based approachesCancer Cell International 2021; 21(1) doi: 10.1186/s12935-021-01924-w
18
Shaohui He, Haifeng Wei, Yifei Ma, Jian Zhao, Wei Xu, Jianru Xiao. Outcomes of metastatic spinal cord compression secondary to primary hepatocellular carcinoma with multidisciplinary treatmentsOncotarget 2017; 8(26): 43439 doi: 10.18632/oncotarget.15708
19
Sheng‑Li Yang, Cui Zeng, Xiefan Fang, Qian‑Jin He, Li‑Ping Liu, Shi‑Yun Bao, Xiaoli Pan, Zhi‑Fan Xiong. Hepatitis B virus upregulates GP73 expression by activating the HIF-2α signaling pathwayOncology Letters 2018;  doi: 10.3892/ol.2018.7955
20
Shuaijun Ma, Yafan Chen, Penghe Quan, Jingliang Zhang, Shichao Han, Guohui Wang, Ruochen Qi, Xiaoyan Zhang, Fuli Wang, Jianlin Yuan, Xiaojian Yang, Weijing Jia, Weijun Qin. NPAS2 promotes aerobic glycolysis and tumor growth in prostate cancer through HIF-1A signalingBMC Cancer 2023; 23(1) doi: 10.1186/s12885-023-10685-w
21
Néstor Prieto-Domínguez, Carolina Méndez-Blanco, Sara Carbajo-Pescador, Flavia Fondevila, Andrés García-Palomo, Javier González-Gallego, José L. Mauriz. Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF-1α and hypoxia-mediated mitophagyOncotarget 2017; 8(53): 91402 doi: 10.18632/oncotarget.20592
22
Aldona Kasprzak, Agnieszka Adamek. Role of Endoglin (CD105) in the Progression of Hepatocellular Carcinoma and Anti-Angiogenic TherapyInternational Journal of Molecular Sciences 2018; 19(12): 3887 doi: 10.3390/ijms19123887
23
Saimila Momin, Ganji Purnachandra Nagaraju. Novel therapeutic approaches for gastrointestinal malignanciesDiagnostics and Therapeutic Advances in GI Malignancies 2020; : 253 doi: 10.1007/978-981-15-5471-1_15
24
Fan Pan, Xin-Rong Lin, Li-Ping Hao, Xiao-Yuan Chu, Hai-Jun Wan, Rui Wang. The Role of RNA Methyltransferase METTL3 in Hepatocellular Carcinoma: Results and PerspectivesFrontiers in Cell and Developmental Biology 2021; 9 doi: 10.3389/fcell.2021.674919
25
Wenyue Gao, Jing Wang, Yuting Xu, Hongbo Yu, Sitong Yi, Changchuan Bai, Qingwei Cong, Ying Zhu. Research progress in the metabolic reprogramming of hepatocellular carcinoma (Review)Molecular Medicine Reports 2024; 30(1) doi: 10.3892/mmr.2024.13255
26
Rona Harari-Steinfeld, Maytal Gefen, Alina Simerzin, Elina Zorde-Khvalevsky, Mila Rivkin, Ezra Ella, Tomer Friehmann, Mordechay Gerlic, Jessica Zucman-Rossi, Stefano Caruso, Mélissa Leveille, Jennifer L. Estall, Daniel S. Goldenberg, Hilla Giladi, Eithan Galun, Zohar Bromberg. The lncRNA H19-Derived MicroRNA-675 Promotes Liver Necroptosis by Targeting FADDCancers 2021; 13(3): 411 doi: 10.3390/cancers13030411
27
Simona Del Giudice, Valentina De Luca, Seyedehnegar Parizadeh, Domenico Russo, Alberto Luini, Rosaria Di Martino. Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in CancerFrontiers in Cell and Developmental Biology 2022; 10 doi: 10.3389/fcell.2022.833663
28
Bao-Hua Li, Malgorzata A. Garstka, Zong-Fang Li. Chemokines and their receptors promoting the recruitment of myeloid-derived suppressor cells into the tumorMolecular Immunology 2020; 117: 201 doi: 10.1016/j.molimm.2019.11.014
29
Pengkai Ma, Jianhua Chen, Haixian Qu, Ye Li, Xiaohui Li, Xuemei Tang, Zhigang Song, Hainan Xin, Jinbang Zhang, Jingxue Nai, Zhiping Li, Zhijun Wang. Hypoxic targeting and activating TH-302 loaded transcatheter arterial embolization microsphereDrug Delivery 2020; 27(1): 1412 doi: 10.1080/10717544.2020.1831102
30
Qiangnu Zhang, Qian Cheng, Mengting Xia, Xiaotao Huang, Xiaoyan He, Juan Liao. Hypoxia-Induced lncRNA-NEAT1 Sustains the Growth of Hepatocellular Carcinoma via Regulation of miR-199a-3p/UCK2Frontiers in Oncology 2020; 10 doi: 10.3389/fonc.2020.00998
31
Kunyuan Wang, Chenxi Duan, Xuejing Zou, Yang Song, Wenwen Li, Lushan Xiao, Jie Peng, Liheng Yao, Qian Long, Li Liu. Increased mediator complex subunit 15 expression is associated with poor prognosis in hepatocellular carcinomaOncology Letters 2018;  doi: 10.3892/ol.2018.7820
32
Qiangnu Zhang, Lijun Qiao, Quan Liu, Xiangpan Kong, Jun Hu, Weibin Hu, Zongze Wu, Mingyue Li, Liping Liu. Hypoxia associated multi-omics molecular landscape of tumor tissue in patients with hepatocellular carcinomaAging 2021; 13(5): 6525 doi: 10.18632/aging.202723
33
Honglin Yan, Na He, Shuixiang He. HCG15 is a hypoxia-responsive lncRNA and facilitates hepatocellular carcinoma cell proliferation and invasion by enhancing ZNF641 transcriptionBiochemical and Biophysical Research Communications 2022; 608: 170 doi: 10.1016/j.bbrc.2022.03.143
34
Min Li, Yujie Su, Fangrong Zhang, Kerong Chen, Xiangting Xu, Lin Xu, Jianping Zhou, Wei Wang. A dual-targeting reconstituted high density lipoprotein leveraging the synergy of sorafenib and antimiRNA21 for enhanced hepatocellular carcinoma therapyActa Biomaterialia 2018; 75: 413 doi: 10.1016/j.actbio.2018.05.049
35
Sheng-Li Yang, Quan-Guang Ren, Tao Zhang, Xiaoli Pan, Lu Wen, Jian-Li Hu, Chao Yu, Qian-Jin He. Hepatitis B virus X protein and hypoxia-inducible factor-1α stimulate Notch gene expression in liver cancer cellsOncology Reports 2017; 37(1): 348 doi: 10.3892/or.2016.5211
36
Wen-Sheng Tzeng, Wei-Lin Teng, Pao-Hsien Huang, Tzu-Ching Lin, Feng-Lin Yen, Yow-Ling Shiue. Pterostilbene Nanoparticles Downregulate Hypoxia-Inducible Factors in Hepatoma Cells Under Hypoxic ConditionsInternational Journal of Nanomedicine 2021; : 867 doi: 10.2147/IJN.S282172
37
Rajesh P. Shah, Paul F. Laeseke, Lewis K. Shin, Frederick T. Chin, Nishita Kothary, George M. Segall. Limitations of Fluorine 18 Fluoromisonidazole in Assessing Treatment-induced Tissue Hypoxia after Transcatheter Arterial Embolization of Hepatocellular Carcinoma: A Prospective Pilot StudyRadiology: Imaging Cancer 2022; 4(3) doi: 10.1148/rycan.210094
38
Wafaa Abumustafa, Darko Castven, Fatemeh Saheb Sharif-Askari, Batoul Abi Zamer, Mawieh Hamad, Jens-Uwe Marquardt, Jibran Sualeh Muhammad. PRMT5 Mediated HIF1α Signaling and Ras-Related Nuclear Protein as Promising Biomarker in Hepatocellular CarcinomaBiology 2024; 13(4): 216 doi: 10.3390/biology13040216
39
Xiu Lv, Jincheng Li, Chuhong Zhang, Tian Hu, Sai Li, Sha He, Hanxing Yan, Yixi Tan, Mingsheng Lei, Meiling Wen, Jianhong Zuo. The role of hypoxia-inducible factors in tumor angiogenesis and cell metabolismGenes & Diseases 2017; 4(1): 19 doi: 10.1016/j.gendis.2016.11.003
40
Huirong Xu, Yeqiang Chen, Zhongchao Li, Hao Zhang, Jingzhou Liu, Jianjun Han. The hypoxia-inducible factor 1 inhibitor LW6 mediates the HIF-1α/PD-L1 axis and suppresses tumor growth of hepatocellular carcinoma in vitro and in vivoEuropean Journal of Pharmacology 2022; 930: 175154 doi: 10.1016/j.ejphar.2022.175154
41
Hong Wu, Tao Wang, Yiqiang Liu, Xin Li, Senlin Xu, Changtao Wu, Hongbo Zou, Mianfu Cao, Guoxiang Jin, Jinyi Lang, Bin Wang, Baohua Liu, Xiaolin Luo, Chuan Xu. Mitophagy promotes sorafenib resistance through hypoxia-inducible ATAD3A dependent AxisJournal of Experimental & Clinical Cancer Research 2020; 39(1) doi: 10.1186/s13046-020-01768-8
42
Yijun Mei, Lu Tang, Qiaqia Xiao, Ziqi Zhang, Ziyao Zhang, Jing Zang, Jianping Zhou, Ying Wang, Wei Wang, Min Ren. Reconstituted high density lipoprotein (rHDL), a versatile drug delivery nanoplatform for tumor targeted therapyJournal of Materials Chemistry B 2021; 9(3): 612 doi: 10.1039/D0TB02139C
43
Jelena Djokic Kovac, Tamara Milovanovic, Vladimir Dugalic, Igor Dumic. Pearls and pitfalls in magnetic resonance imaging of hepatocellular carcinomaWorld Journal of Gastroenterology 2020; 26(17): 2012-2029 doi: 10.3748/wjg.v26.i17.2012
44
Lijun Qiao, Weibin Hu, Linzhi Li, Xin Chen, Liping Liu, Jingbo Wang. USP11 promotes glycolysis by regulating HIF‐1α stability in hepatocellular carcinomaJournal of Cellular and Molecular Medicine 2024; 28(2) doi: 10.1111/jcmm.18017
45
Zhe Li, Jinshuai Lan, Ya Wu, Lixia Chen, Donghao Gu, Liyan Sun, Siqi Yang, Yi Shen, Tong Zhang, Yue Ding. Sensitizing sorafenib to hepatocellular carcinoma with dual-targeted and pH-responsive nanodrugs via overcoming the hypoxia tumor microenvironmentChemical Engineering Journal 2024; : 157231 doi: 10.1016/j.cej.2024.157231
46
Yihui Ma, Wenwen Sun, Qiangnu Zhang, Bingfang Gao, Wen Cai, QinLiang Liu, Juan Liao, Xinli Wang. lncRNA BSG-AS1 is hypoxia-responsive and promotes hepatocellular carcinoma by enhancing BSG mRNA stabilityBiochemical and Biophysical Research Communications 2021; 566: 101 doi: 10.1016/j.bbrc.2021.06.002
47
Frank Jühling, Antonio Saviano, Clara Ponsolles, Laura Heydmann, Emilie Crouchet, Sarah C Durand, Houssein El Saghire, Emanuele Felli, Véronique Lindner, Patrick Pessaux, Nathalie Pochet, Catherine Schuster, Eloi R Verrier, Thomas F Baumert. Hepatitis B virus compartmentalization and single-cell differentiation in hepatocellular carcinomaLife Science Alliance 2021; 4(9): e202101036 doi: 10.26508/lsa.202101036
48
Fei Huang, Junying Chen, Ruilong Lan, Zeng Wang, Ruiqing Chen, Jingan Lin, Lengxi Fu. Hypoxia induced δ-Catenin to enhance mice hepatocellular carcinoma progression via Wnt signalingExperimental Cell Research 2019; 374(1): 94 doi: 10.1016/j.yexcr.2018.11.011
49
Takashi Himoto, Tsutomu Masaki. Current Trends on the Involvement of Zinc, Copper, and Selenium in the Process of HepatocarcinogenesisNutrients 2024; 16(4): 472 doi: 10.3390/nu16040472
50
Sandeep Arora, Roberta Catania, Amir Borhani, Natally Horvat, Kathryn Fowler, Carla Harmath. HCC: role of pre- and post-treatment tumor biology in driving adverse outcomes and rare responses to therapyAbdominal Radiology 2021; 46(8): 3686 doi: 10.1007/s00261-021-03192-8
51
Xiaomeng Dai, Jian Ruan, Yixuan Guo, Zhu Sun, Junqing Liu, Xuanwen Bao, Hangyu Zhang, Qiong Li, Chanqi Ye, Xun Wang, Chun-Xia Zhao, Feng Zhou, Jianpeng Sheng, Dong Chen, Peng Zhao. Enhanced radiotherapy efficacy and induced anti-tumor immunity in HCC by improving hypoxia microenvironment using oxygen microcapsulesChemical Engineering Journal 2021; 422: 130109 doi: 10.1016/j.cej.2021.130109
52
Cynthia Ju, Sean P. Colgan, Holger K. Eltzschig. Hypoxia-inducible factors as molecular targets for liver diseasesJournal of Molecular Medicine 2016; 94(6): 613 doi: 10.1007/s00109-016-1408-1
53
Tian-yi Zhou, Lin-han Zhuang, Yan Hu, Yu-lu Zhou, Wen-kai Lin, Dan-dan Wang, Zi-qian Wan, Lin-lin Chang, Ying Chen, Mei-dan Ying, Zi-bo Chen, Song Ye, Jian-shu Lou, Qiao-jun He, Hong Zhu, Bo Yang. Inactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cellsScientific Reports 2016; 6(1) doi: 10.1038/srep30483
54
Fei Huang, Junying Chen, Ruilong Lan, Zeng Wang, Ruiqing Chen, Jingan Lin, Lurong Zhang, Lengxi Fu. δ-Catenin peptide vaccines repress hepatocellular carcinoma growth via CD8+ T cell activationOncoImmunology 2018; : e1450713 doi: 10.1080/2162402X.2018.1450713
55
Mi Kyoung Song, Gi Beom Kim, Eun Jung Bae, Young Ah Lee, Hyun-Young Kim, Seung-Kee Min, Jung Hee Kim, Jae-Kyung Won. Pheochromocytoma and paraganglioma in Fontan patients: Common more than expectedCongenital Heart Disease 2018; 13(4): 608 doi: 10.1111/chd.12625
56
Mirella Pastore, Giulia Lori, Alessandra Gentilini, Maria Letizia Taddei, Giovanni Di Maira, Claudia Campani, Stefania Recalcati, Pietro Invernizzi, Fabio Marra, Chiara Raggi. Multifaceted Aspects of Metabolic Plasticity in Human Cholangiocarcinoma: An Overview of Current PerspectivesCells 2020; 9(3): 596 doi: 10.3390/cells9030596
57
Huamei Wei, Zuoming Xu, Liucui Chen, Qing Wei, Zihua Huang, Guoman Liu, Wenchuan Li, Jianchu Wang, Qianli Tang, Jian Pu. Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1α/VEGF signalingCell Death & Disease 2022; 13(2) doi: 10.1038/s41419-022-04505-5
58
Jian Yan, Yi‐Xuan Deng, Yu‐Lian Cai, Wen‐Dong Cong. LncRNA MIR17HG promotes the proliferation, migration, and invasion of retinoblastoma cells by up‐regulating HIF‐1α expression via sponging miR‐155‐5pThe Kaohsiung Journal of Medical Sciences 2022; 38(6): 554 doi: 10.1002/kjm2.12523
59
Wanyuan Ruan, Yushi Yang, Qionghua Yu, Tiejun Huang, Yaofen Wang, Li Hua, Zhirui Zeng, Runsang Pan. FUT11 is a target gene of HIF1α that promotes the progression of hepatocellular carcinomaCell Biology International 2021; 45(11): 2275 doi: 10.1002/cbin.11675
60
Hui‐Hui Zhang, Ying Zhang, Yan‐Na Cheng, Fu‐Lian Gong, Zhan‐Qi Cao, Lu‐Gang Yu, Xiu‐Li Guo. Metformin incombination with curcumin inhibits the growth, metastasis, and angiogenesis of hepatocellular carcinoma in vitro and in vivoMolecular Carcinogenesis 2018; 57(1): 44 doi: 10.1002/mc.22718
61
Imanol Zubiete-Franco, Juan L. García-Rodríguez, Fernando Lopitz-Otsoa, Marina Serrano-Macia, Jorge Simon, Pablo Fernández-Tussy, Lucía Barbier-Torres, David Fernández-Ramos, Virginia Gutiérrez-de-Juan, Sergio López de Davalillo, Onintza Carlevaris, Adolfo Beguiristain Gómez, Erica Villa, Diego Calvisi, César Martín, Edurne Berra, Patricia Aspichueta, Naiara Beraza, Marta Varela-Rey, Matias Ávila, Manuel S. Rodríguez, José M. Mato, Irene Díaz-Moreno, Antonio Díaz-Quintana, Teresa C. Delgado, María L. Martínez-Chantar. SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancerEBioMedicine 2019; 40: 406 doi: 10.1016/j.ebiom.2018.12.031
62
Dashuai Yang, Fangrui Zhao, Yu Zhou, Yanbing Zhang, Jie Shen, Bin Yu, Kailiang Zhao, Youming Ding. S100A16 is a potential target for reshaping the tumor microenvironment in the hypoxic context of liver cancerInternational Immunopharmacology 2024; 134: 112076 doi: 10.1016/j.intimp.2024.112076
63
Xuejing Wang, Ling Yin, Mengyin Chai, Buxin Kou, Xiaoni Liu, Xiaojun Wang. Hu-Qi-Zheng-Xiao Decoction Inhibits the Metastasis of Hepatocellular Carcinoma Cells by Suppressing the HIF-1α Signaling Pathway to Inhibit EMT, LCSC, and Angiogenic ProcessIntegrative Cancer Therapies 2024; 23 doi: 10.1177/15347354231226126
64
Rui Huang, Lijun Zhang, Jinmei Jin, Yudong Zhou, Hongwei Zhang, Chao Lv, Dong Lu, Ye Wu, Hong Zhang, Sanhong Liu, Hongzhuan Chen, Xin Luan, Weidong Zhang. Bruceine D inhibits HIF-1α-mediated glucose metabolism in hepatocellular carcinoma by blocking ICAT/β-catenin interactionActa Pharmaceutica Sinica B 2021; 11(11): 3481 doi: 10.1016/j.apsb.2021.05.009
65
Hae Seong Song, Young Ho Song, Nem Singh, Hyunuk Kim, Hyelin Jeon, Inhye Kim, Se Chan Kang, Ki-Whan Chi. New Self-assembled Supramolecular Bowls as Potent Anticancer Agents for Human Hepatocellular CarcinomaScientific Reports 2019; 9(1) doi: 10.1038/s41598-018-36755-9
66
Siti A Sulaiman, Nadiah Abu, Nurul-Syakima Ab-Mutalib, Teck Yew Low, Rahman Jamal. Signatures of Gene Expression, DNA Methylation and microRNAs of Hepatocellular Carcinoma with Vascular InvasionFuture Oncology 2019; 15(22): 2603 doi: 10.2217/fon-2018-0909
67
Huahua Tu, Wei Wang, Yanqing Feng, Linfei Zhang, Huadong Zhou, Caitao Cheng, Lei Ji, Qinghe Cai, Yong Feng. β-Patchoulene represses hypoxia-induced proliferation and epithelial-mesenchymal transition of liver cancer cellsBioengineered 2022; 13(5): 11907 doi: 10.1080/21655979.2022.2065945
68
Xuhua Duan, Wenze Xu, Hao Li, Manzhou Wang, Wenhui Wang, Huibin Lu, Yancang Zhang, Xinwei Han. Nrf2-siRNA Enhanced the Anti-Tumor Effects of As2O3 in 5-Fluorouracil-Resistant Hepatocellular Carcinoma by Inhibiting HIF-1α/HSP70 SignalingJournal of Hepatocellular Carcinoma 2022; : 1341 doi: 10.2147/JHC.S388077
69
Chunyu Zhao, Shanshuo Liu, Feng Gao, Yawen Zou, Zhigang Ren, Zujiang Yu. The role of tumor microenvironment reprogramming in primary liver cancer chemotherapy resistanceFrontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.1008902
70
Yang Wang, Kazuki Takeishi, Zhao Li, Eduardo Cervantes-Alvarez, Alexandra Collin de l'Hortet, Jorge Guzman-Lepe, Xiao Cui, Jiye Zhu. Microenvironment of a tumor-organoid system enhances hepatocellular carcinoma malignancy-related hallmarksOrganogenesis 2017; 13(3): 83 doi: 10.1080/15476278.2017.1322243
71
Zhan-Jun Ma, Hu Yan, Ya-Jiao Wang, Yang Yang, Xiao-Bin Li, An-Cheng Shi, Xu Jing-Wen, Lu Yu-Bao, Lu Li, Xue-Xi Wang. Proteomics analysis demonstrating rosmarinic acid suppresses cell growth by blocking the glycolytic pathway in human HepG2 cellsBiomedicine & Pharmacotherapy 2018; 105: 334 doi: 10.1016/j.biopha.2018.05.129
72
Peng Yuan, Tao Yang, Jiao Mu, Jing Zhao, Yi Yang, Zhaoyong Yan, Yiran Hou, Cheng Chen, Jinliang Xing, Hongxin Zhang, Jibin Li. Circadian clock gene NPAS2 promotes reprogramming of glucose metabolism in hepatocellular carcinoma cellsCancer Letters 2020; 469: 498 doi: 10.1016/j.canlet.2019.11.024
73
Ala’a Al Hrout, Karla Cervantes-Gracia, Richard Chahwan, Amr Amin. Modelling liver cancer microenvironment using a novel 3D culture systemScientific Reports 2022; 12(1) doi: 10.1038/s41598-022-11641-7
74
Inho Choi, Saipriya Lammata, Neha Merchant, Dongkyoo Park. Role of Transcription Factors in Gastrointestinal Malignancies2017; : 465 doi: 10.1007/978-981-10-6728-0_35
75
Wenqi Qiu, Song Zhang, Wei Yu, Jian Liu, Huiling Wu. Non-coding RNAs in hepatocellular carcinoma metastasis: Remarkable indicators and potential oncogenic mechanismComputers in Biology and Medicine 2024; 180: 108867 doi: 10.1016/j.compbiomed.2024.108867
76
Joon Ho Lee, Wonhee Hur, Sung Woo Hong, Jung-Hee Kim, Sung Min Kim, Eun Byul Lee, Seung Kew Yoon. ELK3 promotes the migration and invasion of liver cancer stem cells by targeting HIF-1αOncology Reports 2017; 37(2): 813 doi: 10.3892/or.2016.5293
77
Sung Min Kim, Jang Mi Han, Tuoi Thi Le, Jae Kyung Sohng, Hye Jin Jung. Anticancer and Antiangiogenic Activities of Novel α-Mangostin Glycosides in Human Hepatocellular Carcinoma Cells via Downregulation of c-Met and HIF-1αInternational Journal of Molecular Sciences 2020; 21(11): 4043 doi: 10.3390/ijms21114043
78
Jinghe Xia, Iwata Ozaki, Sachiko Matsuhashi, Takuya Kuwashiro, Hirokazu Takahashi, Keizo Anzai, Toshihiko Mizuta. Mechanisms of PKC-Mediated Enhancement of HIF-1α Activity and its Inhibition by Vitamin K2 in Hepatocellular Carcinoma CellsInternational Journal of Molecular Sciences 2019; 20(5): 1022 doi: 10.3390/ijms20051022
79
Tommaso Mello, Irene Simeone, Andrea Galli. Mito-Nuclear Communication in Hepatocellular Carcinoma Metabolic RewiringCells 2019; 8(5): 417 doi: 10.3390/cells8050417
80
Jian Pu, Zebang Qin, Quan Fang, Youguan Huang, Yuan Lu, Wenchuan Li, Jianchu Wang, Qianli Tang, Dongyun Zeng, Huamei Wei. Hypoxia-induced HIF1A activates DUSP18-mediated MAPK14 dephosphorylation to promote hepatocellular carcinoma cell migration and invasionPathology - Research and Practice 2022; 237: 153955 doi: 10.1016/j.prp.2022.153955
81
Jacintha O’Sullivan, Joanne Lysaght, Claire L. Donohoe, John V. Reynolds. Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironmentsNature Reviews Gastroenterology & Hepatology 2018; 15(11): 699 doi: 10.1038/s41575-018-0069-7