| For: | Chen H, Shen ZY, Xu W, Fan TY, Li J, Lu YF, Cheng ML, Liu J. Expression of P450 and nuclear receptors in normal and end-stage Chinese livers. World J Gastroenterol 2014; 20(26): 8681-8690 [PMID: 25024626 DOI: 10.3748/wjg.v20.i26.8681] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v20/i26/8681.htm |
| Number | Citing Articles |
| 1 |
Ai-Guo Wang, Ya-Nan Song, Jun Chen, Hui-Ling Li, Jian-Yi Dong, Hai-Peng Cui, Liang Yao, Xue-Feng Li, Wen-Ting Gao, Ze-Wen Qiu, Fu-Jin Wang, Jing-Yu Wang. Activation of RAS/ERK alone is insufficient to inhibit RXRα function and deplete retinoic acid in hepatocytes. Biochemical and Biophysical Research Communications 2014; 452(3) doi: 10.1016/j.bbrc.2014.09.007
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| 2 |
Lili Niu, Philipp E Geyer, Rajat Gupta, Alberto Santos, Florian Meier, Sophia Doll, Nicolai J Wewer Albrechtsen, Sabine Klein, Cristina Ortiz, Frank E Uschner, Robert Schierwagen, Jonel Trebicka, Matthias Mann. Dynamic human liver proteome atlas reveals functional insights into disease pathways. Molecular Systems Biology 2022; 18(5) doi: 10.15252/msb.202210947
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| 3 |
Elsa Lilienberg, Ilse R. Dubbelboer, Amar Karalli, Rimma Axelsson, Torkel B. Brismar, Charlotte Ebeling Barbier, Agneta Norén, Frans Duraj, Mikael Hedeland, Ulf Bondesson, Erik Sjögren, Per Stål, Rickard Nyman, Hans Lennernäs. In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma. Molecular Pharmaceutics 2017; 14(2) doi: 10.1021/acs.molpharmaceut.6b00886
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| 4 |
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| 5 |
Meng-Hui Zhang, Qin-Hai Shen, Zhao-Min Qin, Qiao-Ling Wang, Xi Chen. Systematic tracking of disrupted modules identifies significant genes and pathways in hepatocellular carcinoma. Oncology Letters 2016; 12(5) doi: 10.3892/ol.2016.5039
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| 6 |
Dong Gui Hu, Shashikanth Marri, Ross A. McKinnon, Peter I. Mackenzie, Robyn Meech. Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma. The Journal of Pharmacology and Experimental Therapeutics 2019; 368(3) doi: 10.1124/jpet.118.255018
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| 7 |
Naoko Takebe, Jan H. Beumer, Shivaani Kummar, Brian F. Kiesel, Afshin Dowlati, Geraldine O'Sullivan Coyne, Richard Piekarz, Lawrence Rubinstein, Laura K. Fogli, Ulka Vaishampayan, Sanjay Goel, Cindy L. O'Bryant, Bassel F. El‐Rayes, Vincent Chung, Heinz‐Josef Lenz, Richard Kim, Chandra P. Belani, Joseph M. Tuscano, William Schelman, Nancy Moore, James H. Doroshow, Alice P. Chen. A phase I pharmacokinetic study of belinostat in patients with advanced cancers and varying degrees of liver dysfunction. British Journal of Clinical Pharmacology 2019; 85(11) doi: 10.1111/bcp.14054
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| 8 |
Sylwia Szeląg-Pieniek, Stefan Oswald, Mariola Post, Joanna Łapczuk-Romańska, Marek Droździk, Mateusz Kurzawski. Hepatic drug-metabolizing enzymes and drug transporters in Wilson’s disease patients with liver failure. Pharmacological Reports 2021; 73(5) doi: 10.1007/s43440-021-00290-8
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| 9 |
Patrick C. Flannery, Kodye L. Abbott, Satyanarayana R. Pondugula. Correlation of PPM1A Downregulation with CYP3A4 Repression in the Tumor Liver Tissue of Hepatocellular Carcinoma Patients. European Journal of Drug Metabolism and Pharmacokinetics 2020; 45(2) doi: 10.1007/s13318-019-00595-3
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| 10 |
Xianmei Lv, Gaochen Lan, Lujian Zhu, Qiusheng Guo. Breaking the Barriers of Therapy Resistance: Harnessing Ferroptosis for Effective Hepatocellular Carcinoma Therapy. Journal of Hepatocellular Carcinoma 2024; doi: 10.2147/JHC.S469449
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| 11 |
Xiaoning Gan, Yue Luo, Guanqi Dai, Junhao Lin, Xinhui Liu, Xiangqun Zhang, Aimin Li. Identification of Gene Signatures for Diagnosis and Prognosis of Hepatocellular Carcinomas Patients at Early Stage. Frontiers in Genetics 2020; 11 doi: 10.3389/fgene.2020.00857
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| 12 |
Kangning Zhu, Jing Li, Boya Chen, Xin Liu. A Bayesian-based Approach for Identification of Potential Protein Biomarkers in Hepatocellular Carcinoma. Proceedings of the 2023 15th International Conference on Bioinformatics and Biomedical Technology 2023; doi: 10.1145/3608164.3608214
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| 13 |
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| 14 |
Ditte B. Iversen, Lanfranco Pellesi, Tore B. Stage. Drug Metabolism in Diseases. 2026; doi: 10.1016/B978-0-443-29289-7.00012-6
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| 15 |
Huan Li, Yuan-Fu Lu, Hong Chen, Jie Liu. Dysregulation of metallothionein and circadian genes in human hepatocellular carcinoma. Chronobiology International 2017; 34(2) doi: 10.1080/07420528.2016.1256300
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| 16 |
Zhenhua Zhou, Zhenliang Xiao, Wu Wen, Yongkang Zhu. Quercetin, an ingredient of Jiedu Xiaozheng Yin, alleviates hepatocellular carcinoma progression by regulating CYP1A2/PTEN/PI3K/Akt axis. In Vitro Cellular & Developmental Biology - Animal 2026; doi: 10.1007/s11626-026-01212-9
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| 17 |
Jose J. G. Marin, Candela Cives-Losada, Maitane Asensio, Elisa Lozano, Oscar Briz, Rocio I. R. Macias. Mechanisms of Anticancer Drug Resistance in Hepatoblastoma. Cancers 2019; 11(3) doi: 10.3390/cancers11030407
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| 18 |
Nan Hu, Yanjuan Huang, Xuejiao Gao, Sai Li, Zhixiang Yan, Bin Wei, Ru Yan. Effects of dextran sulfate sodium induced experimental colitis on cytochrome P450 activities in rat liver, kidney and intestine. Chemico-Biological Interactions 2017; 271 doi: 10.1016/j.cbi.2017.04.018
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| 19 |
Yoichi Sasaki, Ryotaro Sakamori, Ryoko Yamada, Minoru Shigekawa, Yuki Tahata, Yuki Makino, Tasuku Nakabori, Takahiro Kodama, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara. Cotreatment with lenvatinib and warfarin potassium caused prothrombin time prolongation. Hepatology Research 2019; 49(11) doi: 10.1111/hepr.13379
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| 20 |
Wufeng Fan, Guangming Ye. Microarray analysis for the identification of specific proteins and functional modules involved in the process of hepatocellular carcinoma originating from cirrhotic liver. Molecular Medicine Reports 2018; doi: 10.3892/mmr.2018.8555
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| 21 |
Joseph M. Collins, Danxin Wang. Cytochrome P450 3A4 (CYP3A4) protein quantification using capillary western blot technology and total protein normalization. Journal of Pharmacological and Toxicological Methods 2021; 112 doi: 10.1016/j.vascn.2021.107117
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| 22 |
Basma Hossam Abdelmonem, Noha M. Abdelaal, Eman K. E. Anwer, Alaa A. Rashwan, Mohamed Ali Hussein, Yasmin F. Ahmed, Rana Khashana, Mireille M. Hanna, Anwar Abdelnaser. Decoding the Role of CYP450 Enzymes in Metabolism and Disease: A Comprehensive Review. Biomedicines 2024; 12(7) doi: 10.3390/biomedicines12071467
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| 23 |
J Xue, W Zhu, J Song, Y Jiao, J Luo, C Yu, J Zhou, J Wu, M Chen, W-Q Ding, J Cao, S Zhang. Activation of PPARα by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/β-catenin pathway. Oncogene 2018; 37(7) doi: 10.1038/onc.2017.401
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| 24 |
Xi Ma, Lin Zhou, Shusen Zheng. Transcriptome analysis revealed key prognostic genes and microRNAs in hepatocellular carcinoma. PeerJ 2020; 8 doi: 10.7717/peerj.8930
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| 25 |
Jukun Wang, Ke Han, Chao Zhang, Xin Chen, Yu Li, Linzhong Zhu, Tao Luo. Identification and validation of ADME genes as prognosis and therapy markers for hepatocellular carcinoma patients. Bioscience Reports 2021; 41(5) doi: 10.1042/BSR20210583
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| 26 |
Ming-Liang Cheng, Yuan-Fu Lu, Hong Chen, Zhong-Yang Shen, Jie Liu. Liver expression of Nrf2-related genes in different liver diseases. Hepatobiliary & Pancreatic Diseases International 2015; 14(5) doi: 10.1016/S1499-3872(15)60425-8
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| 27 |
Martin Krkoška, Jana Svobodová, Markéta Kabátková, Ondřej Zapletal, Alena Hyršlová Vaculová, Jana Nekvindová, Jan Vondráček. Deregulation of signaling pathways controlling cell survival and proliferation in cancer cells alters induction of cytochrome P450 family 1 enzymes. Toxicology 2021; 461 doi: 10.1016/j.tox.2021.152897
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| 28 |
Jie Pan, Yuan Lu, Shuai Zhang, Yueting Li, Jia Sun, Hua Chunhua Liu, Zipeng Gong, Jing Huang, Chuang Cao, Yonglin Wang, Yongjun Li, Ting Liu. Differential changes in the pharmacokinetics of doxorubicin in diethylnitrosamine-induced hepatocarcinoma model rats. Xenobiotica 2020; 50(10) doi: 10.1080/00498254.2020.1765049
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| 29 |
Sudhir Kumar, Jiang Wang, Richa Rani, Chandrashekhar R. Gandhi, Gianfranco Alpini. Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice. PLOS ONE 2016; 11(1) doi: 10.1371/journal.pone.0147864
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| 30 |
Xiaoyan Li, Yiyan Lu, Xiaojun Ou, Sijing Zeng, Ying Wang, Xiaoxiao Qi, Lijun Zhu, Zhongqiu Liu. Changes and sex- and age-related differences in the expression of drug metabolizing enzymes in a KRAS-mutant mouse model of lung cancer. PeerJ 2020; 8 doi: 10.7717/peerj.10182
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| 31 |
Gargi Dixit, Arati Prabhu. The pleiotropic peroxisome proliferator activated receptors: Regulation and therapeutics. Experimental and Molecular Pathology 2022; 124 doi: 10.1016/j.yexmp.2021.104723
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| 32 |
Tongmeng Yan, Linlin Lu, Cong Xie, Jiamei Chen, Xiaojuan Peng, Lijun Zhu, Ying Wang, Qiang Li, Jian Shi, Fuyuan Zhou, Ming Hu, Zhongqiu Liu. Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients. Molecular Cancer Therapeutics 2015; 14(12) doi: 10.1158/1535-7163.MCT-15-0274
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| 33 |
Jianqing Yu, Nuozhou Wang, Zhongqin Gong, Liping Liu, Shengli Yang, George Gong Chen, Paul Bo San Lai. Cytochrome P450 1A2 overcomes nuclear factor kappa B-mediated sorafenib resistance in hepatocellular carcinoma. Oncogene 2021; 40(3) doi: 10.1038/s41388-020-01545-z
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| 34 |
Florian Klomp, Christoph Wenzel, Marek Drozdzik, Stefan Oswald. Drug–Drug Interactions Involving Intestinal and Hepatic CYP1A Enzymes. Pharmaceutics 2020; 12(12) doi: 10.3390/pharmaceutics12121201
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| 35 |
Peipei Hao, Ruifeng Ding, Xuefeng Bai, Aimin Zhang, Ziqi Jin, Jiayi Zhang, Yongzhi Xue. Sea buckthorn regulates PXR/CAR/NF-κB signaling and restores CYP2C metabolic function in BCG-induced hepatitis. Journal of Ethnopharmacology 2025; 351 doi: 10.1016/j.jep.2025.120142
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| 36 |
João Victor Dutra Gomes, Corinna Herz, Simone Helmig, Nadja Förster, Inga Mewis, Evelyn Lamy. Drug-Drug Interaction Potential, Cytotoxicity, and Reactive Oxygen Species Production of Salix Cortex Extracts Using Human Hepatocyte-Like HepaRG Cells. Frontiers in Pharmacology 2021; 12 doi: 10.3389/fphar.2021.779801
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| 37 |
Jianwai Ren, George G. Chen, Yi Liu, Xianwei Su, Baoguang Hu, Billy C. S. Leung, Y. Wang, Rocky L. K. Ho, Shengli Yang, Gang Lu, C. G. Lee, Paul B. S. Lai, Zhiyuan Gong. Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma. PLOS ONE 2016; 11(4) doi: 10.1371/journal.pone.0153863
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| 38 |
Martin Krkoška, Jana Nekvindová, Kateřina Nevědělová, Veronika Zubáňová, Lenka Radová, Jan Vondráček, Jarmila Herůdková, Ondřej Slabý, Igor Kiss, Lucia Bohovicová, Pavel Fabian, Zuzana Tylichová, Zdeněk Kala, Petr Kysela, Lenka Ostřížková, Vladimír Palička, Alena Hyršlová Vaculová. Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma. Pharmacological Reports 2022; 74(1) doi: 10.1007/s43440-021-00338-9
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| 39 |
Yuseok Moon, Tamás Korcsmáros, Arulkumar Nagappan, Navin Ray. MicroRNA target-based network predicts androgen receptor-linked mycotoxin stress. Ecotoxicology and Environmental Safety 2022; 230 doi: 10.1016/j.ecoenv.2021.113130
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| 40 |
Jiaqi Wang, Lushan Yu, Huidi Jiang, Xiaoli Zheng, Su Zeng. Epigenetic Regulation of Differentially Expressed Drug-Metabolizing Enzymes in Cancer. Drug Metabolism and Disposition 2020; 48(9) doi: 10.1124/dmd.120.000008
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| 41 |
Manuela G. Neuman, Stephen Malnick, Yaakov Maor, Radu M. Nanau, Ehud Melzer, Peter Ferenci, Helmut K. Seitz, Sebastian Mueller, Haim Mell, Didier Samuel, Lawrence B. Cohen, Kusum K. Kharbanda, Natalia A. Osna, Murali Ganesan, Kyle J. Thompson, Iain H. McKillop, Abraham Bautista, Ramon Bataller, Samuel W. French. Alcoholic liver disease: Clinical and translational research. Experimental and Molecular Pathology 2015; 99(3) doi: 10.1016/j.yexmp.2015.09.001
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| 42 |
Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng, Shuqing Chen. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma. Drug Metabolism and Disposition 2016; 44(10) doi: 10.1124/dmd.116.070243
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| 43 |
Haixing Li, Jed N. Lampe. Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism. Archives of Biochemistry and Biophysics 2019; 673 doi: 10.1016/j.abb.2019.108078
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| 44 |
Yu-Jie Jiang, Ye-Ming Cao, Yong-Bing Cao, Tian-Hua Yan, Cheng-Lin Jia, Ping He. A Review: Cytochrome P450 in Alcoholic and Non-Alcoholic Fatty Liver Disease. Diabetes, Metabolic Syndrome and Obesity 2024; doi: 10.2147/DMSO.S449494
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| 45 |
Yingying Yang, Ekaterina Parfenova, Nikolina Vrdoljak, Mark Minden, Jessica Luc, Andrew C. Doxey, Paul A. Spagnuolo. Pharmacological inhibition of Peroxisome Proliferation-Activated Receptor Delta (PPARδ) imparts selective leukemia cell death. Cancer & Metabolism 2025; 13(1) doi: 10.1186/s40170-025-00402-5
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| 46 |
Jana Nekvindova, Alena Mrkvicova, Veronika Zubanova, Alena Hyrslova Vaculova, Pavel Anzenbacher, Pavel Soucek, Lenka Radova, Ondrej Slaby, Igor Kiss, Jan Vondracek, Alena Spicakova, Lucia Bohovicova, Pavel Fabian, Zdenek Kala, Vladimir Palicka. Hepatocellular carcinoma: Gene expression profiling and regulation of xenobiotic-metabolizing cytochromes P450. Biochemical Pharmacology 2020; 177 doi: 10.1016/j.bcp.2020.113912
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| 47 |
Yan Tan, Mina Wang, Ke Yang, Tiange Chi, Zehuan Liao, Peng Wei. PPAR-α Modulators as Current and Potential Cancer Treatments. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.599995
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| 48 |
Ettore Mosca, Roberta Alfieri, Luciano Milanesi, Ranjit Ray. Diffusion of Information throughout the Host Interactome Reveals Gene Expression Variations in Network Proximity to Target Proteins of Hepatitis C Virus. PLoS ONE 2014; 9(12) doi: 10.1371/journal.pone.0113660
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| 49 |
Jeong Eun Yoo, Ji Hae Nahm, Young-Joo Kim, Youngsic Jeon, Young Nyun Park. The dual role of transforming growth factor-beta signatures in human B viral multistep hepatocarcinogenesis: early and late responsive genes. Journal of Liver Cancer 2022; 22(2) doi: 10.17998/jlc.2022.04.20
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| 50 |
Xianqiang Zhou, Fang Tan, Suxian Zhang, An'an Wang, Tiansong Zhang. A Strategy based on Bioinformatics and Machine Learning Algorithms Reveals
Potential Mechanisms of Shelian Capsule against Hepatocellular Carcinoma. Current Pharmaceutical Design 2024; 30(5) doi: 10.2174/0113816128284465240108071554
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| 51 |
Maya Okamura, Ryota Shizu, Takuomi Hosaka, Takamitsu Sasaki, Kouichi Yoshinari. Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro. Drug Metabolism and Pharmacokinetics 2019; 34(4) doi: 10.1016/j.dmpk.2019.04.005
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| 52 |
Cheng-Lin Fu, Bing Pan, Ju-Hua Pan, Mei-Fu Gan. Metallothionein 1M suppresses tumorigenesis in hepatocellular carcinoma. Oncotarget 2017; 8(20) doi: 10.18632/oncotarget.16521
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| 53 |
D. Desaulniers, N. Khan, C. Cummings-Lorbetskie, K. Leingartner, G-H. Xiao, A. Williams, C.L. Yauk. Effects of cross-fostering and developmental exposure to mixtures of environmental contaminants on hepatic gene expression in prepubertal 21 days old and adult male Sprague-Dawley rats. Journal of Toxicology and Environmental Health, Part A 2019; 82(1) doi: 10.1080/15287394.2018.1542360
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| 54 |
Hyuk Soo Eun, Sang Yeon Cho, Byung Seok Lee, Sup Kim, In‐Sang Song, Kwangsik Chun, Cheong‐Hae Oh, Min‐Kyung Yeo, Seok Hyun Kim, Kyung‐Hee Kim. Cytochrome P450 4A11 expression in tumor cells: A favorable prognostic factor for hepatocellular carcinoma patients. Journal of Gastroenterology and Hepatology 2019; 34(1) doi: 10.1111/jgh.14406
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| 55 |
Ruohao Zhang, Miao Huang, Hong Wang, Shengming Wu, Jiali Yao, Yingying Ge, Yufei Lu, Qiping Hu. Identification of Potential Biomarkers From Hepatocellular Carcinoma With MT1 Deletion. Pathology and Oncology Research 2021; 27 doi: 10.3389/pore.2021.597527
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| 56 |
Christoph G Dietrich, Oliver Götze, Andreas Geier. Molecular changes in hepatic metabolism and transport in cirrhosis and their functional importance. World Journal of Gastroenterology 2016; 22(1): 72-88 doi: 10.3748/wjg.v22.i1.72
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