| For: | Alexopoulou A, Karayiannis P. HBeAg negative variants and their role in the natural history of chronic hepatitis B virus infection. World J Gastroenterol 2014; 20(24): 7644-7652 [PMID: 24976702 DOI: 10.3748/wjg.v20.i24.7644] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v20/i24/7644.htm |
| Number | Citing Articles |
| 1 |
Xiangjun Zhai, Liguo Zhu, Jie Jiang, Ci Song, Hong Peng, Jiao Qian, MingHao Zhou, Yan Zhou, Qungang Wang, Jianfang Xu, Zhijian Wang, Hongjian Liu, Min Fan, Zhibin Hu, Hongbin Shen, Fengcai Zhu. Virological activity in treatment-naïve HBeAg-negative HBV-infected adult patients. Medicine 2020; 99(29) doi: 10.1097/MD.0000000000021179
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| 2 |
Qin-Yan Chen, Hui-Hua Jia, Xue-Yan Wang, Yun-Liang Shi, Lu-Juan Zhang, Li-Ping Hu, Chao Wang, Xiang He, Tim J. Harrison, J. Brooks Jackson, Li Wu, Zhong-Liao Fang. Analysis of entire hepatitis B virus genomes reveals reversion of mutations to wild type in natural infection, a 15 year follow-up study. Infection, Genetics and Evolution 2022; 97 doi: 10.1016/j.meegid.2021.105184
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| 3 |
Da-Wu Zeng, Jing Dong, Jie-Min Zhang, Yue-Yong Zhu, Jia-Ji Jiang, Yu-Rui Liu. HBeAg-negative chronic hepatitis patients should be monitored more strictly: A cross-sectional retrospective study on antiviral treatment-naïve patients. Journal of Medical Virology 2015; 87(10) doi: 10.1002/jmv.24217
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| 4 |
Xiao-Ling Wang, Jian-Ping Ren, Xue-Qing Wang, Xiao-Hong Wang, Shao-Fang Yang, Yi Xiong. Mutations in pre-core and basic core promoter regions of hepatitis B virus in chronic hepatitis B patients. World Journal of Gastroenterology 2016; 22(11): 3268-3274 doi: 10.3748/wjg.v22.i11.3268
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| 5 |
Stijn F. H. Raven, Barry de Heus, Albert Wong, Hans L. Zaaijer, Jim E. van Steenbergen. Fluctuation of Viremia in Hepatitis B Virus–Infected Healthcare Workers Performing Exposure-Prone Procedures in the Netherlands. Infection Control & Hospital Epidemiology 2016; 37(6) doi: 10.1017/ice.2016.49
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| 6 |
Liguo Zhu, Xiangjun Zhai, Qungang Wang, Jie Jiang, Hong Peng, Ci Song, Zijun Ge, Jiao Qian, MingHao Zhou, Yan Zhou, Jianfang Xu, Hongjian Liu, Dong Hang, Zhibin Hu, Hongbin Shen, Fengcai Zhu. Incidence and determinants of spontaneous hepatitis B surface antigen seroclearance and seroconversion in hepatitis B e antigen‐negative chronic infection patients: A population‐based prospective cohort. Journal of Viral Hepatitis 2018; 25(12) doi: 10.1111/jvh.12978
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| 7 |
Chong Wang, Lin Lin, Da Peng Ding. Dynamic changes of chronic hepatitis B patient with loss of surface antigen: a case report. BMC Infectious Diseases 2025; 25(1) doi: 10.1186/s12879-025-11337-z
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| 8 |
Salma Madihi, Hicham Charoute, Samia Boukaira, Hind Bouafi, Warda Baha, Abdelmajid Zyad, Abdelouaheb Benani. Virological characterization of Hepatitis B virus infection in Morocco: A ten-years study (2014 – 2023). Diagnostic Microbiology and Infectious Disease 2024; 110(4) doi: 10.1016/j.diagmicrobio.2024.116502
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| 9 |
A cautionary note to hepatitis B e antigen (HBeAg)‐negative test results in pregnant women in an area prevalent of HBeAg‐negative chronic hepatitis B. Journal of Medical Virology 2023; 95(1) doi: 10.1002/jmv.28125
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| 10 |
Feilin Ge, Yan Yang, Lanlan Si, Yuanhua Li, Wenxia Zhao, Zhaofang Bai, Yan Liu, Xiaohe Xiao. The efficacy and safety of Chinese patent medicine LWWL combined with nucleoside/nucleotide analogues in treatment of chronic hepatitis B: A systematic review and meta-analysis. Gastroenterology & Endoscopy 2023; 1(4) doi: 10.1016/j.gande.2023.07.001
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| 11 |
. 2019; doi: 10.70675/4f30fc49z85ebz4907z93b1z66a91d34560a
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| 12 |
Yandan Wu, Yan Ding, Chuanlai Shen. A Systematic Review of T Cell Epitopes Defined from the Proteome of Hepatitis B Virus. Vaccines 2022; 10(2) doi: 10.3390/vaccines10020257
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| 13 |
Junhyup Song, Seung Jun Choi, Sinyoung Kim, Younhee Park, Gadissa Bedada Hundie. Comparative evaluation of four fully automated immunoanalyzers for the simultaneous detection of HBeAg and Anti-HBe. PLOS One 2025; 20(9) doi: 10.1371/journal.pone.0331381
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| 14 |
Robério Amorim de Almeida Pondé. Dynamic profile of the HBeAg-anti-HBe system in acute and chronic hepatitis B virus infection: A clinical-laboratory approach. Molecular Biology Reports 2021; 48(1) doi: 10.1007/s11033-020-06056-4
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| 15 |
Pia L. Seiz, Heiko Slanina, John Ziebuhr, Wolfram H. Gerlich, Dieter Glebe, Christian G. Schüttler. Studies of nosocomial outbreaks of hepatitis B in nursing homes in Germany suggest a major role of hepatitis B e antigen expression in disease severity and progression. International Journal of Medical Microbiology 2015; 305(7) doi: 10.1016/j.ijmm.2015.08.016
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| 16 |
Kiyasha Padarath, Aurélie Deroubaix, Anna Kramvis. The Complex Role of HBeAg and Its Precursors in the Pathway to Hepatocellular Carcinoma. Viruses 2023; 15(4) doi: 10.3390/v15040857
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| 17 |
Yingfeng Lu, Chiyan Zhou, Ren Yan, Jiangshan Lian, Huan Cai, Jiong Yu, Deyin Chen, Xiaoling Su, Jiajie Qian, Yida Yang, Lanjuan Li. Dynamic metabolic profiles for HBeAg seroconversion in chronic hepatitis B (CHB) patients by gas chromatography-mass spectrometry (GC-MS). Journal of Pharmaceutical and Biomedical Analysis 2021; 206 doi: 10.1016/j.jpba.2021.114349
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| 18 |
Irma V Machado. Autoimmune Manifestations in Chronic Hepatitis B. Gastroenterology & Hepatology: Open Access 2017; 8(1) doi: 10.15406/ghoa.2017.08.00268
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| 19 |
Changhui Wu, Fengwei Liu, Xiao Li, Xiaojin Li, Hui Li, Sihang Zhang, Xiaohui Yan, Taicheng Zhou, Jia Wei. Adaptive Evolution and Distinct Mutation Signatures of Full‐Length HBV Quasispecies in HBeAg‐Negative Chronic Hepatitis B. MicrobiologyOpen 2025; 14(6) doi: 10.1002/mbo3.70175
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| 20 |
Naoto Sato, Shunji Watanabe, Kouichi Miura, Rie Goka, Naoki Morimoto, Yoshinari Takaoka, Hiroaki Nomoto, Mamiko Tsukui, Norio Isoda, Shigeo Nagashima, Masaharu Takahashi, Hiroaki Okamoto, Hironori Yamamoto. Acute Liver Failure Caused by the Transmission of Hepatitis B Virus from the Spouse after 38 Years of Marriage. Internal Medicine 2019; 58(20) doi: 10.2169/internalmedicine.3028-19
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| 21 |
Cecilia G. Giadans, Daniela A. Ríos, Beatriz Ameigeiras, Adriana M. Pietrantonio, Néstor L. Lucatelli, Leila Haddad, Eduardo Mullen, Fabiana Heinrich, Elena De Matteo, Diego Flichman, Pamela Valva, María V. Preciado. Chronic hepatitis B: The interplay between intrahepatic lymphocyte population and viral antigens in relation to liver damage. Journal of Viral Hepatitis 2019; 26(6) doi: 10.1111/jvh.13078
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| 22 |
Qian Zhang, Da-Chuan Cai, Peng Hu, Hong Ren. Low-level viremia in nucleoside analog-treated chronic hepatitis B patients. Chinese Medical Journal 2021; 134(23) doi: 10.1097/CM9.0000000000001793
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| 23 |
. 2021; doi: 10.70675/7d320f74z5435z443fz872cz0cf9decdb479
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| 24 |
Upkar S. Gill, Arianna Battisti, Patrick T. F. Kennedy. Emerging tools in the changing landscape of chronic hepatitis B management. Expert Review of Anti-infective Therapy 2019; 17(12) doi: 10.1080/14787210.2019.1694906
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| 25 |
Yong Huang, Haijun Deng, Zhi Peng, Yao Huang, Quanxin Long, Ailong Huang. Mutations of Basal Core Promoter and Precore Regions in Hepatitis B Virus Genotypes B and C. Hepatitis Monthly 2014; 15(1) doi: 10.5812/hepatmon.23034
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| 26 |
Guixin Li, Danli Yang, Xin Liu, Ting Zhang, Hui Liu, Jun Zou, Zimeng Xu, Xiangmei Chen, Lizhong Dai, Hongsong Chen, Fengmin Lu. Precore mutation enhances viral replication to facilitate persistent infection especially in HBeAg-negative patients. Virologica Sinica 2024; 39(2) doi: 10.1016/j.virs.2024.03.003
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| 27 |
Tania Reuter, Michele Soares Gomes-Gouvea, Samira Chuffi, Ulisses Horst Duque, Waltesia Perini, Raymundo Soares Azevedo, João Renato Rebello Pinho. Core Promoter and Pre-Core Variants of the Hepatitis B Virus (HBV) Are Frequent in Chronic Hepatitis B HBeAg-Negative Patients Infected by Genotypes A and D. Viruses 2023; 15(12) doi: 10.3390/v15122339
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| 28 |
Hao Pang, Xinglin Fu, Tianju Li, Bo Qin. Dynamic changes in IFI44L and SAMHD1 mRNA levels in PBMCs are associated with treatment response in HBeAg-negative chronic hepatitis B during peg-IFN-α therapy. Frontiers in Microbiology 2026; 17 doi: 10.3389/fmicb.2026.1976096
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| 29 |
Tonya Mixson-Hayden, Michael A. Purdy, Lilia Ganova-Raeva, Daniel McGovern, Joseph C. Forbi, Saleem Kamili. Evaluation of performance characteristics of hepatitis B e antigen serologic assays. Journal of Clinical Virology 2018; 109 doi: 10.1016/j.jcv.2018.10.005
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| 30 |
Gora Lô, Amina Sow‐Sall, Halimatou Diop‐Ndiaye, Nokoa Chadia Ines Danty Mandiouba, Moussa Thiam, Fatou Diop, Ousseynou Ndiaye, Sokhna Bousso Gueye, Sidy Mouhamed Seck, Abou Abdallah Malick Dioura, Moustapha Mbow, Aïssatou Gaye‐Diallo, Souleymane Mboup, Coumba Touré‐Kâne. Prevalence of hepatitis B markers in Senegalese HIV‐1‐infected patients. Journal of Medical Virology 2016; 88(3) doi: 10.1002/jmv.24344
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| 31 |
Feifei Yang, Xueping Yu, Chenliang Zhou, Richeng Mao, Mengqi Zhu, Haoxiang Zhu, Zhenxuan Ma, Bidisha Mitra, Gan Zhao, Yuxian Huang, Haitao Guo, Bin Wang, Jiming Zhang, Michael D. Robek. Hepatitis B e antigen induces the expansion of monocytic myeloid-derived suppressor cells to dampen T-cell function in chronic hepatitis B virus infection. PLOS Pathogens 2019; 15(4) doi: 10.1371/journal.ppat.1007690
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| 32 |
Host Factors in the Natural History of Chronic Hepatitis B: Role of Genetic Determinants. International Journal of Hepatology 2022; 2022 doi: 10.1155/2022/6046677
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| 33 |
Maria Guido, Alessandra Mangia, Neil D. Theise. MacSween's Pathology of the Liver. 2024; doi: 10.1016/B978-0-7020-8228-3.00006-5
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| 34 |
Moyra Machado Portilho, Marcia Leite Baptista, Messias da Silva, Paulo Sérgio Fonseca de Sousa, Lia Laura Lewis-Ximenez, Elisabeth Lampe, Livia Melo Villar. Usefulness of in-house PCR methods for hepatitis B virus DNA detection. Journal of Virological Methods 2015; 223 doi: 10.1016/j.jviromet.2015.07.010
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| 35 |
Hanna Aberra, Hailemichael Desalegn, Nega Berhe, Girmay Medhin, Kathrine Stene-Johansen, Svein Gunnar Gundersen, Asgeir Johannessen. Early experiences from one of the first treatment programs for chronic hepatitis B in sub-Saharan Africa. BMC Infectious Diseases 2017; 17(1) doi: 10.1186/s12879-017-2549-8
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| 36 |
Lemonica Koumbi, Teresa Pollicino, Giovanni Raimondo, Dimitrios Stampoulis, Salim Khakoo, Peter Karayiannis. Hepatitis B virus basal core promoter mutations show lower replication fitness associated with cccDNA acetylation status. Virus Research 2016; 220 doi: 10.1016/j.virusres.2016.04.022
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| 37 |
Qin Ning, Ting Wu, Hai-Bin Su, Ke Ma, Jun-Ying Qi, Ming Ni, Di Wu. Acute Exacerbation of Chronic Hepatitis B. 2019; doi: 10.1007/978-94-024-1603-9_5
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| 38 |
Richard K. Sterling, Abdus S. Wahed, Gavin Cloherty, Jay H. Hoofnagle, William M. Lee. Acute Hepatitis B Virus Infection in North American Adults. Clinical Gastroenterology and Hepatology 2023; 21(7) doi: 10.1016/j.cgh.2022.09.004
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| 39 |
Bukhari Isah Shuaib, Usman Linda Itunu, Aminat Daud. Clinical utility of hepatitis B core-related antigen in chronic hepatitis B infection: diagnostic, prognostic, and therapeutic implications. Egyptian Liver Journal 2026; 16(1) doi: 10.1186/s43066-026-00512-9
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| 40 |
Yeshambel Belyhun, Uwe Gerd Liebert, Melanie Maier, Jason Blackard. Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia. PLOS ONE 2018; 13(2) doi: 10.1371/journal.pone.0191970
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| 41 |
Sihan Du, Ximin Shen, Yi Sun, Jia Li, Juan Wang, Yiting Cai, He Li. A retrospective study to determine the correlation among HBV PreS1 antigen, HBV e antigen, alanine aminotransferase, and HBV DNA. Clinics and Research in Hepatology and Gastroenterology 2024; 48(6) doi: 10.1016/j.clinre.2024.102369
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| 42 |
Y.W. Zhong, F.L. Di, C. Liu, X.C. Zhang, J.F. Bi, Y.L. Li, S.Q. Wu, H. Dong, L.M. Liu, J. He, Y.M. Shi, H.F. Zhang, M. Zhang. Hepatitis B virus basal core promoter/precore mutants and association with liver cirrhosis in children with chronic hepatitis B virus infection. Clinical Microbiology and Infection 2016; 22(4) doi: 10.1016/j.cmi.2015.10.033
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| 43 |
Daniel Candotti, Birama Diarra, Cyrille Bisseye, Issoufou Tao, Kei Pham Quang, Mahamoudou Sanou, Syria Laperche, Rokia Sanogo, Jean‐Pierre Allain, Jacques Simpore. Molecular characterization of hepatitis B virus in blood donors from Burkina Faso: Prevalence of quasi‐subgenotype A3, genotype E, and mixed infections. Journal of Medical Virology 2016; 88(12) doi: 10.1002/jmv.24589
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| 44 |
So-Young Lee, Yu-Min Choi, Song-Ji Oh, Soo-Bin Yang, JunHyeok Lee, Won-Hyeok Choe, Yoon-Hoh Kook, Bum-Joon Kim. rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C Infections. Frontiers in Immunology 2019; 10 doi: 10.3389/fimmu.2019.01735
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| 45 |
Kiyasha Padarath, Aurélie Deroubaix, Previn Naicker, Stoyan Stoychev, Anna Kramvis. Comparison of the Proteome of Huh7 Cells Transfected with Hepatitis B Virus Subgenotype A1, with or without G1862T. Current Issues in Molecular Biology 2024; 46(7) doi: 10.3390/cimb46070419
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| 46 |
Xue Li, Pei Liu, Zhaohui Wang, Xuefei Wei, Shuai Gao, YuChen Fan, Huihui Liu, Kai Wang. The value of promoter methylation of fibroblast factor 21 (FGF21) in predicting the course of chronic hepatitis B and the occurrence of oxidative stress. Virology Journal 2024; 21(1) doi: 10.1186/s12985-024-02605-6
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| 47 |
Abdullah Ely, Prashika Singh, Tiffany S. Smith, Patrick Arbuthnot. In vitro transcribed mRNA for expression of designer nucleases: Advantages as a novel therapeutic for the management of chronic HBV infection. Advanced Drug Delivery Reviews 2021; 168 doi: 10.1016/j.addr.2020.05.010
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| 48 |
Hanaâ Bazir, Hlima Bessi, Mohammed Nabil Benchekroun, Moulay Mustapha Ennaji. Oncogenic Viruses. 2023; doi: 10.1016/B978-0-12-824152-3.00020-2
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| 49 |
Sergio Hernández, Francisca Álvarez-Astudillo, Daniel Garrido, Cristian Prieto, Alejandra Loyola, Rodrigo A. Villanueva. Canonical and Divergent N-Terminal HBx Isoform Proteins Unveiled: Characteristics and Roles during HBV Replication. Biomedicines 2021; 9(11) doi: 10.3390/biomedicines9111701
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| 50 |
Aya Raed Alheany, Shatha Farouk Abdullah. Status of HBeAg in association with other baseline tests in Iraqi patients with CHB. Research Journal of Pharmacy and Technology 2022; doi: 10.52711/0974-360X.2022.00582
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| 51 |
Mi-Soon Han, Yongjung Park, Hyunjin Nah, Hyon-Suk Kim. Comparison of the QIAGEN artus HBV QS-RGQ Assay With the Roche COBAS AmpliPrep/COBAS TaqMan HBV Assay for Quantifying Viral DNA in Sera of Chronic Hepatitis B Patients. Annals of Laboratory Medicine 2017; 37(3) doi: 10.3343/alm.2017.37.3.248
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| 52 |
Kimia Kardani, Parya Basimi, Mehrshad Fekri, Azam Bolhassani. Antiviral therapy for the sexually transmitted viruses: recent updates on vaccine development. Expert Review of Clinical Pharmacology 2020; 13(9) doi: 10.1080/17512433.2020.1814743
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| 53 |
Simone La Frazia, Alessia Magnapera, Lorenzo Piermatteo, Stefano D’Anna, Leonardo Duca, Valentina Svicher, Romina Salpini. Direct Viral Mechanisms Underlying the Onset of HBV-Related Hepatocellular Carcinoma and Implications for Therapeutic Strategies. Viruses 2026; 18(2) doi: 10.3390/v18020185
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| 54 |
Li-Bo Yan, Xiao-Qiong Tang, Qing-Bo Zhang, Xia Zhu, Lang Bai, Ling-Yao Du, En-Qiang Chen, Hong Tang. Clinical Features of Hepatitis B e-antigen Positive Chronic Hepatitis B Patients co-existing Precore and/or Basal Core Promoter Mutations. Future Virology 2018; 13(10) doi: 10.2217/fvl-2018-0091
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| 55 |
Eman A. El-Maadawy, Roba M. Talaat, Maha M. Ahmed, Soha Z. El-Shenawy. Interleukin-6 promotor gene polymorphisms and susceptibility to chronic hepatitis B virus in Egyptians. Human Immunology 2019; 80(3) doi: 10.1016/j.humimm.2018.12.009
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| 56 |
Shelina Moonsamy, Pavitra Pillay, Nishi Prabdial-Sing, Abram L. Wagner. Hepatitis B infection status among South Africans attending public health facilities over a five-year period: 2015 to 2019. PLOS Global Public Health 2023; 3(9) doi: 10.1371/journal.pgph.0000992
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| 57 |
Dong Hyun Kim, Yu-Min Choi, Junghwa Jang, Bum-Joon Kim. Global prevalence and molecular characteristics of three clades within hepatitis B virus subgenotype C2: Predominance of the C2(3) clade in South Korea. Frontiers in Microbiology 2023; 14 doi: 10.3389/fmicb.2023.1137084
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| 58 |
Cyriac Abby Philips, Shiv Kumar Sarin. Potent antiviral therapy improves survival in acute on chronic liver failure due to hepatitis B virus reactivation. World Journal of Gastroenterology 2014; 20(43): 16037-16052 doi: 10.3748/wjg.v20.i43.16037
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| 59 |
Maisuri T. Chalid, Susan Irawati, Rizalinda Sjahril, Ridha Wahyuni, M. Nasrum Massi, David Muljono. A Cautionary Note to Hepatitis B <i>e</i> ANTIGEN (HBeAg)-Negative Status of Pregnant Women. SSRN Electronic Journal 2020; doi: 10.2139/ssrn.3736190
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| 60 |
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| 61 |
Theodoros Voulgaris, John Vlachogiannakos, Panagiota Ioannidou, Maria-Vasiliki Papageorgiou, Evi Zampeli, Dimitrios Karagiannakis, Anastasia Georgiou, Afroditi Papazoglou, George Karamanolis, George V. Papatheodoridis. Adherence to follow-up and treatment recommendations in Greek and immigrant patients with chronic hepatitis B in Greece. European Journal of Gastroenterology & Hepatology 2017; 29(3) doi: 10.1097/MEG.0000000000000788
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| 62 |
Liyan Lu, Lingjun Yan, Amir Sohrabi, Karin Lindahl, Susanne Cederberg, Raorao Wang, Weimin Ye, Soo Aleman, Margaret Sällberg Chen. The salivary microbiome and oral health status in HBeAg-negative chronic hepatitis B. Journal of Dental Sciences 2024; 19 doi: 10.1016/j.jds.2024.08.016
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| 63 |
Sindhu Vikash, Fnu Vikash, Aarushi Sudan, Bisrat Adal, Donald Kotler. Addressing Barriers to Care in Hepatocellular Carcinoma: Promoting Equity and Access. Cureus 2023; doi: 10.7759/cureus.41893
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| 64 |
Oguntope Adeorike Sobajo, Judith Uche Oguzie, Benjamin Adegboyega, Philomena Eromon, Christian Happi, Isaac Komolafe, Onikepe Folarin. Detection of Immune Escape and Basal Core Promoter/Precore Gene Mutations in Hepatitis B Virus Isolated from Asymptomatic Hospital Attendees in Two Southwestern States in Nigeria. Viruses 2023; 15(11) doi: 10.3390/v15112188
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| 65 |
Hiba Sami, Mohd Asaad, Safiya Firoze, Syed Haider Mehdi Husaini, Parvez A. Khan, Nazish Fatima, Adil Raza, Haris M. Khan. Molecular analysis of HBV pre-core gene mutations in patients co-infected with HIV at a tertiary care hospital in North India.
Access Microbiology
2025; 7(8) doi: 10.1099/acmi.0.000927.v4
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| 66 |
Ganesan Praveenkumar, Chaitali Nikam, Ragoori Venkata Ramana, Sengupta Caesar, Velumani Amruta, Ahmad Riyaj. Comparison of the Amplisure HBV Quantitative Kit with the Qiagen Artus HBV QS-RGQ Assay for Quantifying Viral DNA in Plasma Samples of Monitoring Cases. Intervirology 2021; 64(4) doi: 10.1159/000515905
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