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For: Grundmann O, Yoon SL. Complementary and alternative medicines in irritable bowel syndrome: An integrative view. World J Gastroenterol 2014; 20(2): 346-362 [PMID: 24574705 DOI: 10.3748/wjg.v20.i2.346]
URL: https://www.wjgnet.com/1007-9327/full/v20/i2/346.htm
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Irene X. Y. Wu, Charlene H. L. Wong, Robin S. T. Ho, William K. W. Cheung, Alexander C. Ford, Justin C. Y. Wu, Arthur D. P. Mak, Holger Cramer, Vincent C. H. Chung. Acupuncture and related therapies for treating irritable bowel syndrome: overview of systematic reviews and network meta-analysisTherapeutic Advances in Gastroenterology 2019; 12 doi: 10.1177/1756284818820438
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Domingo De Pedro Jiménez, Violeta Pino Casal. Evolución positiva de una paciente con síndrome de histaminosis alimentaria no alérgica y síndrome de intestino irritableRevista Internacional de Acupuntura 2015; 9(4) doi: 10.1016/j.acu.2015.11.002
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S. Vitta, G. S. Sayuk. Editorial: Tong‐Xie‐Yao‐Fang (TXYF) for irritable bowel syndrome with diarrhoea (IBS‐D)—ancient medicine meets modern studyAlimentary Pharmacology & Therapeutics 2018; 48(4) doi: 10.1111/apt.14902
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YiTian Ying, XiangHou Zheng, Jing Yang, Huiwen Ye, Zhenhao Dong, Youqi Ji, Shengyu Li, Xun Tan, Wei Zhang. Tong-Xie-Yao-Fang ameliorates IBS-D: Potential role of Alistipes finegoldii-associated gut tryptophan indole metabolismJournal of Ethnopharmacology 2026; 371 doi: 10.1016/j.jep.2026.122061
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Jordi Serra, Daniel Pohl, Fernando Azpiroz, Giuseppe Chiarioni, Philippe Ducrotté, Guillaume Gourcerol, A. Pali S. Hungin, Peter Layer, Juan‐Manuel Mendive, Johann Pfeifer, Gerhard Rogler, S. Mark Scott, Magnus Simrén, Peter Whorwell. European society of neurogastroenterology and motility guidelines on functional constipation in adultsNeurogastroenterology & Motility 2020; 32(2) doi: 10.1111/nmo.13762
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Shahnaz Sultan, Ashish Malhotra. Irritable Bowel SyndromeAnnals of Internal Medicine 2017; 166(11) doi: 10.7326/AITC201706060
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Flavia di Michele. Why Use Nutraceutical Strategies for the Irritable Bowel Syndrome?Current Medicinal Chemistry 2022; 29(12) doi: 10.2174/0929867328666210917115255
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Henry Ture Eriksson, Göran Karl Kurlberg, Kristina Ingrid Andrén, Elsa Maria Eriksson. Aspects of the non-pharmacological treatment of irritable bowel syndromeWorld Journal of Gastroenterology 2015; 21(40): 11439-11449 doi: 10.3748/wjg.v21.i40.11439
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Beth Faiman. Diarrhea in Multiple Myeloma: A Review of the LiteratureClinical Journal of Oncology Nursing 2016; 20(4) doi: 10.1188/16.CJON.E100-E105
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Aybala Temel. Herbal Medicine for Autoimmune Diseases2024;  doi: 10.2174/9789815305005124010009
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Jongwon Park, Seok-Jae Ko, Gajin Han, Keumji Kim, Hyejin Jun, Jae-Woo Park. Gwakhyangjeonggi-san for irritable bowel syndromeMedicine 2021; 100(27) doi: 10.1097/MD.0000000000026635
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Xiaoliang Wu, Lu Ju, Yafang Song, Lijun Bai, Menqian Yuan, Wanli Xu, Jing Li, Tiancheng Xu, Lixia Pei, Jianhua Sun. Mechanism of Colonic Slow Wave Rhythm Regulated by Electro-acupuncture Determined using Calcium-Sensitive ReceptorAcupuncture & Electro-Therapeutics Research: International Journal of Integrated Medicine 2021; 45(2) doi: 10.3727/036012921X16112663844842
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Vijaya Kavuri, Nagarathna Raghuram, Ariel Malamud, Senthamil R. Selvan. Irritable Bowel Syndrome: Yoga as Remedial TherapyEvidence-Based Complementary and Alternative Medicine 2015; 2015 doi: 10.1155/2015/398156
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M. de Greck, P. Layer, V. Andresen. Schmerztherapie beim ReizdarmsyndromDer Schmerz 2014; 28(3) doi: 10.1007/s00482-014-1406-6
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I. V. Maev, S. V. Cheremushkin, Yu. A. Kucheryavyi, N. V. Cheremushkina. Pharmacotherapy for irritable bowel syndrome in the context of evidence-based medicineTerapevticheskii arkhiv 2015; 87(2) doi: 10.17116/terarkh20158724-10
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Jiahao Zhang, Xinxue Gao, Yi Qu, Jidong Liu. Comparative efficacy and safety of Chinese medicine external therapies for diarrhea-predominant irritable bowel syndrome: a systematic review and network meta-analysisFrontiers in Medicine 2026; 13 doi: 10.3389/fmed.2026.1867631
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J.M. Remes-Troche, E. Coss-Adame, M. Schmulson, K.R. García-Zermeño, M. Amieva-Balmori, R. Carmona-Sánchez, O. Gómez-Escudero, P.C. Gómez-Castaños, M.E. Icaza-Chávez, A. López-Colombo, E.C. Morel-Cerda, M.Á. Valdovinos-Díaz, L.R. Valdovinos-García, A.S. Villar-Chávez. Pharmacologic treatment of irritable bowel syndrome. Position statement of the Asociación Mexicana de Gastroenterología, 2024Revista de Gastroenterología de México (English Edition) 2025; 90(1) doi: 10.1016/j.rgmxen.2024.10.009
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Serap Parlar Kılıc, Nermin Kılıç, Sibel Sevinç, Cihat Demirel. A Qualitative Study of the Experiences of Complementary and Alternative Medicine Use in Patients With IBS-CHolistic Nursing Practice 2020; 34(3) doi: 10.1097/HNP.0000000000000383
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Tristan Carter, Joshua Z. Goldenberg, Amie Steel. An examination of naturopathic treatment of non-specific gastrointestinal complaints: comparative analysis of two casesIntegrative Medicine Research 2019; 8(3) doi: 10.1016/j.imr.2019.08.001
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Chunpeng Li, Jianmin Li, Qiaorui Zhou, Can Wang, Jiahui Hu, Chang Liu. Effects of Physical Exercise on the Microbiota in Irritable Bowel SyndromeNutrients 2024; 16(16) doi: 10.3390/nu16162657
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Chun-Yan Li, Nurul Ain Mohd Tahir, Shu-Chuen Li. A Systematic Review of Integrated Traditional Chinese and Western Medicine for Managing Irritable Bowel SyndromeThe American Journal of Chinese Medicine 2015; 43(03) doi: 10.1142/S0192415X15500251
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Lin Chang, Carlo Di Lorenzo, Gianrico Farrugia, Frank A. Hamilton, Gary M. Mawe, Pankaj J. Pasricha, John W. Wiley. Functional Bowel Disorders: A Roadmap to Guide the Next Generation of ResearchGastroenterology 2018; 154(3) doi: 10.1053/j.gastro.2017.12.010
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Serap Parlar Kılıc, Nermin Kılıç, Sibel Sevinç, Cihat Demirel. A Qualitative Study of the Experiences of Complementary and Alternative Medicine of Patients With IBS-CHolistic Nursing Practice 2020; 34(5) doi: 10.1097/HNP.0000000000000405
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Gezhi Zhang, Tao Zhang, Zeng Cao, Zijing Tao, Tianhao Wan, Mengxi Yao, Xiaolan Su, Wei Wei. Effects and Mechanisms of Acupuncture on Diarrhea-Predominant Irritable Bowel Syndrome: A Systematic ReviewFrontiers in Neuroscience 2022; 16 doi: 10.3389/fnins.2022.918701
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M. Uwais Ashraf, Deoshree Akhouri, Divyashish Bhardwaj, Bushra Siddiqui. A Study to Evaluate the Effectiveness of “Mindfulness-Based Stress Reduction Therapy(MBSRT)” in Reducing Symptom Severity and Improving Quality of Life in Patients Suffering From Irritable Bowel SyndromeJournal of Clinical Gastroenterology 2023; 57(9) doi: 10.1097/MCG.0000000000001800
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Anselm Meyer, Jonas Auer, Lorena Cascant‐Ortolano, Niclas Schreiber, Amy Zimmermann‐Klemd, Carsten Gründemann, Philipp Busche, Jörg Schirra, Mark R. Fox. Systematic Review and Meta‐Analysis: Plant‐Based Therapy for Irritable Bowel SyndromePhytotherapy Research 2026;  doi: 10.1002/ptr.70421
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Xiaoxue Jiang, Xiutian Guo, Jianhua Zhou, Sunsong Ye, Ahmed Faeq Hussein. Acupuncture and Moxibustion in the Treatment of Adult Diarrhea Irritable Bowel Syndrome: A Network Meta-analysisComputational and Mathematical Methods in Medicine 2022; 2022 doi: 10.1155/2022/9919839
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Clinical Roundup: Selected Treatment Options for Irritable Bowel Syndrome—Part 2Alternative and Complementary Therapies 2015; 21(5) doi: 10.1089/act.2015.29026.cru
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Albert Orock, Tian Yuan, Beverley Greenwood-Van Meerveld. Importance of Non-pharmacological Approaches for Treating Irritable Bowel Syndrome: Mechanisms and Clinical RelevanceFrontiers in Pain Research 2021; 1 doi: 10.3389/fpain.2020.609292
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Justin Whetten, Laura Medina, Crystal Krabbenhoft, Vanessa Will, Mary Reising, Breanna K. Maska, Jennifer K. Phillips. Health Resource Utilization and Cost Impact of Integrative Medicine Services for Newly Diagnosed Chronic Pain PatientsJournal of Integrative and Complementary Medicine 2024; 30(11) doi: 10.1089/jicm.2024.0093
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Jian-kui Wang, Juan Liu. Neuromuscular electrical stimulation as an adjunctive therapy to drotaverine hydrochloride for treating patients with diarrhea-predominant irritable bowel syndromeMedicine 2018; 97(29) doi: 10.1097/MD.0000000000011478
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Sabine Krüger. Osteopathische Behandlung des Reizdarmsyndroms – ein ReviewOsteopathische Medizin 2016; 17(4) doi: 10.1016/S1615-9071(16)30083-1
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Pratima Dibba, Megha Kothari, Irwin Grosman. Nutrition, Weight, and Digestive Health2022;  doi: 10.1007/978-3-030-94953-2_11
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P. Enck, N. Mazurak. Nichtmedikamentöse Therapie des ReizdarmsyndromsDer Gastroenterologe 2017; 12(2) doi: 10.1007/s11377-017-0144-6
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Rui Fu, Mingxian Chen, Yu Chen, Guoqun Mao, Saiyue Liu. Expression and clinical significance of 5‑HT and 5‑HT3R in the intestinal mucosa of patient with diarrhea‑type irritable bowel syndromeExperimental and Therapeutic Medicine 2019;  doi: 10.3892/etm.2019.7297
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Yongqi Du, Haiyan Xu, Jun Xiong, Zhengfan Wang, Shuang Yang. Tracing Evolution of Hotspots and Frontiers: A Bibliometric Exploration of Acupuncture Therapy in Irritable Bowel SyndromeJournal of Multidisciplinary Healthcare 2025;  doi: 10.2147/JMDH.S554094
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Natalia Płóciennik-Korycka, Sara Maria Pani, Bogumiła Bruc, Paolo Contu, Magdalena Wrzesińska. Exploring manual therapy in the management of irritable bowel syndrome in adults: A scoping reviewComplementary Therapies in Medicine 2025; 89 doi: 10.1016/j.ctim.2025.103136
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Yuanzhen Bai, Meilin Yu, Chunyan Weng, Jingli Xu, Mingxu Zheng, Bin Lv. Autonomic nervous system dysfunction in irritable bowel syndrome: pathophysiology and therapeutic implicationsFrontiers in Neuroscience 2026; 20 doi: 10.3389/fnins.2026.1832540
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Regina Sierżantowicz, Jolanta Lewko, Grażyna Jurkowska. The Impact of an Individual Educational Program on the Quality of Life and Severity of Symptoms of Patients with Irritable Bowel SyndromeInternational Journal of Environmental Research and Public Health 2020; 17(12) doi: 10.3390/ijerph17124230
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Jelena Šuran, Nikola Pavlović, Joško Božić, Marko Kumrić, Katarina Vukojević, Natalija Filipović, Božo Radić. IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological InterventionsAntibiotics 2026; 15(3) doi: 10.3390/antibiotics15030251
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Zeynep Erdogan, Mehmet Ali Kurçer. Dietary Supplement Use in Gastrointestinal Symptom Management and Effect on Hopelessness Levels in Patients With Irritable Bowel SyndromeHolistic Nursing Practice 2019; 33(3) doi: 10.1097/HNP.0000000000000324
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Mei Kwan Lai, Cho Wing Lo, Hongwei Zhang, Chi Him Sum, Kam Leung CHAN, Pui Kuan Cheong, Tianhe Song, Zhixiu LIN, Siew C. Ng, Justin Wu. Chinese Herbal Medicines Complementary to Mesalazine for Ulcerative Colitis: A Systematic Review with Meta-AnalysisSSRN Electronic Journal 2022;  doi: 10.2139/ssrn.4162345
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Lijiang Ji, Xiaoying Zhao, Yuyan Zhang, Ping Zhao, Rui Gong, Fang Li, Hua Huang. Efficacy and safety of Qinghua Zhixie Decoction against diarrhea-predominate irritable bowel syndromeMedicine 2022; 101(9) doi: 10.1097/MD.0000000000028895
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Diego Currò, Gianluca Ianiro, Silvia Pecere, Stefano Bibbò, Giovanni Cammarota. Probiotics, fibre and herbal medicinal products for functional and inflammatory bowel disordersBritish Journal of Pharmacology 2017; 174(11) doi: 10.1111/bph.13632
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Mohammad Rostamkhani, Masoud Etedali, Azam Malek Hoseini, Hooman Mohammad talebi. Comparative effects of thyme and ginger on gastrointestinal symptom relief: A randomized controlled trialAdvances in Integrative Medicine 2025; 12(4) doi: 10.1016/j.aimed.2025.100584
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Hye-Youn Kim, Cho-Een Kim, Dool-Ri Oh, Yonguk Kim, Chul-Yung Choi, Jaeyong Kim. Development and Validation of a High-Performance Liquid Chromatography Method to Quantify Marker Compounds in Lysimachia vulgaris var. davurica and Its Effects in Diarrhea-Predominant Irritable Bowel SyndromeMolecules 2024; 29(7) doi: 10.3390/molecules29071489
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Binyamin Binyaminy, Eric J. Haas. A Short Profile of Hypnotherapy Licensure in IsraelInternational Journal of Clinical and Experimental Hypnosis 2016; 64(4) doi: 10.1080/00207144.2016.1209056
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Weidong Wang, Fang Wang, Feng Fan, Ana Cristina Sedas, Jian Wang. Mind–Body Interventions for Irritable Bowel Syndrome Patients in the Chinese Population: a Systematic Review and Meta-AnalysisInternational Journal of Behavioral Medicine 2017; 24(2) doi: 10.1007/s12529-016-9589-0
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Melissa G. Hunt, Connie Wong, Syed Aajmain, Ifeoluwa Dawodu. Fecal incontinence in people with self-reported irritable bowel syndrome: Prevalence and quality of lifeJournal of Psychosomatic Research 2018; 113 doi: 10.1016/j.jpsychores.2018.07.015
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Ya Feng, Lu Hang, Yan Zhou, Feng-Ru Jiang, Jian-Ye Yuan. Gut microbiota plays a role in irritable bowel syndrome by regulating 5-HT metabolismWorld Chinese Journal of Digestology 2022; 30(21) doi: 10.11569/wcjd.v30.i21.941
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Vijaya Kavuri, Pooja Selvan, Alireza Tabesh, Nagarathna Raghuram, Senthamil R. Selvan. Remedial Yoga module improves symptoms of irritable bowel syndrome: Replication in the Wait-list group and sustained improvements at 6 monthsEuropean Journal of Integrative Medicine 2015; 7(6) doi: 10.1016/j.eujim.2015.11.002
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Mohammed Saif Anaam, Saeed Obaid Alfadly, Abdulmajeed Alqasoumi, Mohammed Almunef, Sulaiman Ibrahim Alsohaim, Suhaj Abdulsalim, Khalid Siddeeg, Bader Abdulah Al Harbi, Bader Theyab AL Mutairi, Waleed M. Altowayan. Community pharmacists’ preparedness in irritable bowel syndrome management: A descriptive, community-based study on awareness, perceptions, and clinical support practices in Qassim, Saudi ArabiaMedicine 2026; 105(27) doi: 10.1097/MD.0000000000049312
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Ulrike Halsband, Thomas Gerhard Wolf. Functional Changes in Brain Activity After Hypnosis: Neurobiological Mechanisms and Application to Patients with a Specific Phobia—Limitations and Future DirectionsInternational Journal of Clinical and Experimental Hypnosis 2019; 67(4) doi: 10.1080/00207144.2019.1650551
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Md Moniruzzaman, Ayesha Shah, Mark Morrison, Natasha Koloski, Kok Ann Gwee, Minhu Chen, YongSung Kim, Kana Ayaki, Thomas Efferth, Gerald Holtmann. Mechanisms of action and clinical effectiveness of herbal treatments for disorders of gut-brain interactionDigestive and Liver Disease 2025; 57(9) doi: 10.1016/j.dld.2025.07.010
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Acharaporn Duangjai, Kwanchanok Parseatsook, Wittawas Sajjapong, Surasak Saokaew. Assessment of Polygonum odoratum Lour. Leaf Extract on Rat's Ileum Contraction and the Mechanisms InvolvedJournal of Medicinal Food 2020; 23(11) doi: 10.1089/jmf.2020.4769
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Tiziana Larussa, Marianna Rossi, Evelina Suraci, Raffaella Marasco, Maria Imeneo, Ludovico Abenavoli, Francesco Luzza. Use of Complementary and Alternative Medicine by Patients with Irritable Bowel Syndrome According to the Roma IV Criteria: A Single-Center Italian SurveyMedicina 2019; 55(2) doi: 10.3390/medicina55020046
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Vijaya Kavuri, Pooja Selvan, Ariel Malamud, Nagarathna Raghuram, Senthamil R. Selvan. Remedial yoga module remarkably improves symptoms in irritable bowel syndrome patients: A 12-week randomized controlled trialEuropean Journal of Integrative Medicine 2015; 7(6) doi: 10.1016/j.eujim.2015.11.001
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Qian Li, Bei-ping Zhang, Shao-gang Huang, Wen-wei Ouyang, Jian-hui Xie, Ze-huai Wen, Xiao-bo Yang. Efficacy and indication optimization of Chinese medicine (Tiao-Chang Ke-Min granules) for diarrhea-predominant irritable bowel syndrome: study protocol for a randomized controlled trialTrials 2018; 19(1) doi: 10.1186/s13063-018-2754-9
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Oliver Grundmann, Saunjoo L. Yoon, Sydney Mason, Keore Smith. Gastrointestinal symptom improvement from fiber, STW 5, peppermint oil, and probiotics use—Results from an online surveyComplementary Therapies in Medicine 2018; 41 doi: 10.1016/j.ctim.2018.10.003
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Shu-Chuen Li, Chun-Yan Li. Treatment of irritable bowel syndrome in China: A reviewWorld Journal of Gastroenterology 2015; 21(8): 2315-2322 doi: 10.3748/wjg.v21.i8.2315
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Yanhui Peng, Hui You, Xiaoman Chen, Yanbing Chen, Yiling Yang, Jianpeng Huang, Nenggui Xu, Jianhua Liu. Effect of electroacupuncture at homotopic and heterotopic acupoints on abdominal pain in patients with irritable bowel syndrome: study protocol for a randomized controlled trialTrials 2018; 19(1) doi: 10.1186/s13063-018-2948-1
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Melissa A. Nickles, Aliza Hasan, Anastasia Shakhbazova, Sarah Wright, Cynthia J. Chambers, Raja K. Sivamani. Alternative Treatment Approaches to Small Intestinal Bacterial Overgrowth: A Systematic ReviewThe Journal of Alternative and Complementary Medicine 2021; 27(2) doi: 10.1089/acm.2020.0275
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Melissa G. Hunt. Using Central Neuromodulators and Psychological Therapies to Manage Patients with Disorders of Gut-Brain Interaction2019;  doi: 10.1007/978-3-030-18218-2_5
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Yujin Choi, Na-Yeon Ha, Ae-Ran Kim, Haein Jeong, Ojin Kwon, Ki-Sun Park, Jieun Kim, Jinsung Kim, Hyungjun Kim. Modified Gwakjeongtang for Diarrhea-Predominant Irritable Bowel Syndrome: Study Protocol for a Randomized, Double-Blind, Placebo-Controlled, Pilot Clinical TrialInternational Journal of General Medicine 2024;  doi: 10.2147/IJGM.S447701
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Anamaria Cozma-Petruţ, Felicia Loghin, Doina Miere, Dan Lucian Dumitraşcu. Diet in irritable bowel syndrome: What to recommend, not what to forbid to patients!World Journal of Gastroenterology 2017; 23(21): 3771-3783 doi: 10.3748/wjg.v23.i21.3771
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Adam J. Kuchnia, Beth Conlon, Norman Greenberg. Natural Bioactive Food Components for Improving Enteral Tube Feeding Tolerance in Adult Patient PopulationsNutrition in Clinical Practice 2018; 33(1) doi: 10.1177/0884533617722164