For: | Tang XP, Tang GD, Fang CY, Liang ZH, Zhang LY. Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells. World J Gastroenterol 2013; 19(10): 1582-1592 [PMID: 23538603 DOI: 10.3748/wjg.v19.i10.1582] |
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URL: | https://www.wjgnet.com/1007-9327/full/v19/i10/1582.htm |
Number | Citing Articles |
1 |
Qing Jin, Cunzhi Lin, Xinhong Zhu, Yiwei Cao, Caihong Guo, Lijun Wang. 125I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts. Radiation Oncology 2020; 15(1) doi: 10.1186/s13014-020-01682-5
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2 |
H. Dommisch, J. Winter, W. Götz, J. Miesen, A. Klein, L. Hierse, J. Deschner, A. Jäger, J. Eberhard, S. Jepsen. Effect of growth factors on antimicrobial peptides and pro-inflammatory mediators during wound healing. Clinical Oral Investigations 2015; 19(2): 209 doi: 10.1007/s00784-014-1239-9
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3 |
Yan Chen, Hong Shang, Shunli Zhang, Xiaohong Zhang. Retracted: Ginsenoside Rh2 inhibits proliferation and migration of medulloblastoma Daoy by down‐regulation of microRNA‐31. Journal of Cellular Biochemistry 2018; 119(8): 6527 doi: 10.1002/jcb.26716
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4 |
Muhammad Zubair Siddiqi, Chang-Hao Cui, Seul-Ki Park, Nam Soo Han, Sun-Chang Kim, Wan-Taek Im, Hua Zhou. Comparative analysis of the expression level of recombinant ginsenoside-transforming β-glucosidase in GRAS hosts and mass production of the ginsenoside Rh2-Mix. PLOS ONE 2017; 12(4): e0176098 doi: 10.1371/journal.pone.0176098
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5 |
Xun Li, Shifeng Chu, Meiyu Lin, Yan Gao, Yingjiao Liu, Songwei Yang, Xin Zhou, Yani Zhang, Yaomei Hu, Huiqin Wang, Naihong Chen. Anticancer property of ginsenoside Rh2 from ginseng. European Journal of Medicinal Chemistry 2020; 203: 112627 doi: 10.1016/j.ejmech.2020.112627
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6 |
YingMin Qu, Feihu Zhao, Xinyue Wang, Jinyun Liu, Jingmei Li, Zhengxun Song, Zuobin Wang. Cardiomyocyte contractile force changes in response to AGRWE detected by AFM. Micro & Nano Letters 2019; 14(5): 511 doi: 10.1049/mnl.2018.5458
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7 |
Xiang Li, Nan Wang, Yutong Wu, Yidan Liu, Ruoyu Wang. ALDH6A1 weakens the progression of colon cancer via modulating the RAS/RAF/MEK/ERK pathway in cancer cell lines. Gene 2022; 842: 146757 doi: 10.1016/j.gene.2022.146757
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8 |
Keke LI, Zhongyu LI, Lei Men, Wei LI, Xiaojie GONG. Potential of ginsenoside Rh2and its derivatives as anti-cancer agents. Chinese Journal of Natural Medicines 2022; 20(12): 881 doi: 10.1016/S1875-5364(22)60193-6
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9 |
Hwa-Seung Yoo, Mi-Kyung Jeong, Chong-Kwan Cho. General and Genetic Toxicology of Enzyme-Treated Ginseng Extract. Journal of Pharmacopuncture 2016; 19(3): 213 doi: 10.3831/KPI.2016.19.022
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10 |
Ting Xia, Jiancheng Wang, Yingnan Wang, Yuanyuan Wang, Jianye Cai, Min Wang, Qidan Chen, Jia Song, Ziqi Yu, Wei Huang, Jianpei Fang. Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells. Oncotarget 2016; 7(19): 27336 doi: 10.18632/oncotarget.8285
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11 |
Xuewei Ye, Siran Yu, Ying Liang, Haocai Huang, Xiao-Yuan Lian, Zhizhen Zhang. Bioactive triterpenoid saponins and phenolic compounds against glioma cells. Bioorganic & Medicinal Chemistry Letters 2014; 24(22): 5157 doi: 10.1016/j.bmcl.2014.09.087
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12 |
Ting Xia, Ying-Nan Wang, Chuan-Xin Zhou, Li-Mei Wu, Yong Liu, Qian-Hong Zeng, Xiang-Long Zhang, Jia-Hui Yao, Min Wang, Jian-Pei Fang. Ginsenoside Rh2 and Rg3 inhibit cell proliferation and induce apoptosis by increasing mitochondrial reactive oxygen species in human leukemia Jurkat cells. Molecular Medicine Reports 2017; 15(6): 3591 doi: 10.3892/mmr.2017.6459
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13 |
Tereza Cristina da Silva, Bruno Cogliati, Andréia Oliveira Latorre, Gokithi Akisue, Márcia Kazumi Nagamine, Mitsue Haraguchi, Daiane Hansen, Daniel Soares Sanches, Maria Lúcia Zaidan Dagli. Pfaffosidic Fraction fromHebanthe paniculataInduces Cell Cycle Arrest and Caspase-3-Induced Apoptosis in HepG2 Cells. Evidence-Based Complementary and Alternative Medicine 2015; 2015: 1 doi: 10.1155/2015/835796
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14 |
Priyanka Singh, Hina Singh, Verónica Castro-Aceituno, Sungeun Ahn, Yeon Ju Kim, Mohamed El-Agamy Farh, Deok Chun Yang. Engineering of mesoporous silica nanoparticles for release of ginsenoside CK and Rh2 to enhance their anticancer and anti-inflammatory efficacy: in vitro studies. Journal of Nanoparticle Research 2017; 19(7) doi: 10.1007/s11051-017-3949-9
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15 |
Jong Dae Park. Chemistry of Korean Foods and Beverages. ACS Symposium Series 2019; 1303: 149 doi: 10.1021/bk-2019-1303.ch011
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16 |
Junyu Wu, Guoyi Tang, Chien-Shan Cheng, Ranna Yeerken, Yau-Tuen Chan, Zhiwen Fu, Yi-Chao Zheng, Yibin Feng, Ning Wang. Traditional Chinese medicine for the treatment of cancers of hepatobiliary system: from clinical evidence to drug discovery. Molecular Cancer 2024; 23(1) doi: 10.1186/s12943-024-02136-2
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17 |
Li Yang, Hecun Zou, Yongchao Gao, Junjia Luo, Xiaonv Xie, Wenhui Meng, Honghao Zhou, Zhirong Tan. Insights into gastrointestinal microbiota-generated ginsenoside metabolites and their bioactivities. Drug Metabolism Reviews 2020; 52(1): 125 doi: 10.1080/03602532.2020.1714645
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18 |
Yi Yang, Yi Nan, Yuhua Du, Wenjing Liu, Na Ning, Guoqing Chen, Qian Gu, Ling Yuan. Ginsenosides in cancer: Proliferation, metastasis, and drug resistance. Biomedicine & Pharmacotherapy 2024; 177: 117049 doi: 10.1016/j.biopha.2024.117049
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19 |
Zhi-Mei You, Liang Zhao, Jing Xia, Qiang Wei, Yu-Min Liu, Xiao-Yan Liu, Di-Long Chen, Jing Li. Down-regulation of Phosphoglucose Isomerase/Autocrine Motility Factor Enhances Gensenoside Rh2 Pharmacological Action on Leukemia KG1α Cells. Asian Pacific Journal of Cancer Prevention 2014; 15(3): 1099 doi: 10.7314/APJCP.2014.15.3.1099
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20 |
Shuai Bian, Meichen Liu, Song Yang, Shuyan Lu, Siming Wang, Xueyuan Bai, Daqing Zhao, Jiawen Wang. 20(S)-Ginsenoside Rh2-induced apoptosis and protective autophagy in cervical cancer cells by inhibiting AMPK/mTOR pathway. Bioscience, Biotechnology, and Biochemistry 2021; 86(1): 92 doi: 10.1093/bbb/zbab189
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21 |
Luciana Fernández, Ana Lucía Reviglio, Daniel A. Heredia, Gustavo M. Morales, Marisa Santo, Luis Otero, Fabrisio Alustiza, Ana Cecilia Liaudat, Pablo Bosch, Enrique L. Larghi, Andrea B.J. Bracca, Teodoro S. Kaufman. Langmuir-Blodgett monolayers holding a wound healing active compound and its effect in cell culture. A model for the study of surface mediated drug delivery systems. Heliyon 2021; 7(3): e06436 doi: 10.1016/j.heliyon.2021.e06436
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22 |
Wenxin Huang, Liwen Sun, Baihui Wang, Yan Ma, Dahong Yao, Weina Han, Libo Wang. Ginsenosides, potent inhibitors of sialyltransferase. Zeitschrift für Naturforschung C 2020; 75(1-2): 41 doi: 10.1515/znc-2019-0150
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23 |
Dan-Dan Wang, Yeon-Ju Kim, Nam In Baek, Ramya Mathiyalagan, Chao Wang, Yan Jin, Xing Yue Xu, Deok-Chun Yang. Glycosyltransformation of ginsenoside Rh2 into two novel ginsenosides using recombinant glycosyltransferase from Lactobacillus rhamnosus and its in vitro applications. Journal of Ginseng Research 2021; 45(1): 48 doi: 10.1016/j.jgr.2019.11.004
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24 |
Meiyan Li, Dandan Tang, Ting Yang, Die Qian, Runchun Xu. Apoptosis Triggering, an Important Way for Natural Products From Herbal Medicines to Treat Pancreatic Cancers. Frontiers in Pharmacology 2022; 12 doi: 10.3389/fphar.2021.796300
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25 |
Meng Wang, Shi-Ju Yan, Hong-Tao Zhang, Nan Li, Tao Liu, Ying-Long Zhang, Xiao-Xiang Li, Qiong Ma, Xiu-Chun Qiu, Qing-Yu Fan, Bao-An Ma. Ginsenoside Rh2 enhances the antitumor immunological response of a melanoma mice model. Oncology Letters 2017; 13(2): 681 doi: 10.3892/ol.2016.5490
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26 |
Peng Li, Junfeng Ye, Yue Zhang, Ziqi Wang, Sujuan Ren, Xuwen Li, Yongri Jin. Centrifugation free and air-assisted liquid-liquid microextraction based on deep eutectic solvent for determination of rare ginsenosides in Kang'ai injection. Microchemical Journal 2018; 142: 313 doi: 10.1016/j.microc.2018.07.012
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27 |
Shaoyi Li, Yun Gao, Weining Ma, Wenchang Guo, Gang Zhou, Tianci Cheng, Yunhui Liu. EGFR signaling-dependent inhibition of glioblastoma growth by ginsenoside Rh2. Tumor Biology 2014; 35(6): 5593 doi: 10.1007/s13277-014-1739-x
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28 |
Lin Li, Po Sing Leung. Use of herbal medicines and natural products: An alternative approach to overcoming the apoptotic resistance of pancreatic cancer. The International Journal of Biochemistry & Cell Biology 2014; 53: 224 doi: 10.1016/j.biocel.2014.05.021
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29 |
Jianjun Yang, Donghong Yuan, Tongchao Xing, Hongli Su, Shengjun Zhang, Jiansheng Wen, Qiqiang Bai, Dongmei Dang. Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation through blocking PDZ-binding kinase/T-LAK cell-originated protein kinase. Journal of Ginseng Research 2016; 40(4): 400 doi: 10.1016/j.jgr.2016.03.007
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30 |
Sang Yeol Lee. Anti-Metastatic and Anti-Inflammatory Effects of Matrix Metalloproteinase Inhibition by Ginsenosides. Biomedicines 2021; 9(2): 198 doi: 10.3390/biomedicines9020198
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31 |
Seun Eui Kim, Myoung-Hoon Lee, Hye-Myoung Jang, Wan-Taek Im, Joontaik Lee, Sang-Hwan Kim, Gwang Joo Jeon. Anticancer activity of ginsenosides Rh2 on various cancer cells. Journal of Animal Reproduction and Biotechnology 2023; 38(3): 131 doi: 10.12750/JARB.38.3.131
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32 |
Ning Guan, Xiaochuan Huo, Zhenxing Zhang, Shoudan Zhang, Junsheng Luo, Wenshi Guo. Ginsenoside Rh2 inhibits metastasis of glioblastoma multiforme through Akt-regulated MMP13. Tumor Biology 2015; 36(9): 6789 doi: 10.1007/s13277-015-3387-1
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33 |
Chenchen Li, Huan Gao, Xuemei Feng, Chuyao Bi, Jing Zhang, Jianyuan Yin. Ginsenoside Rh2 impedes proliferation and migration and induces apoptosis by regulating NF‐κB, MAPK, and PI3K/Akt/mTOR signaling pathways in osteosarcoma cells. Journal of Biochemical and Molecular Toxicology 2020; 34(12) doi: 10.1002/jbt.22597
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34 |
Qingchuan Zhang, Bin Hong, Songhua Wu, Tianli Niu. Inhibition of prostatic cancer growth by ginsenoside Rh2. Tumor Biology 2015; 36(4): 2377 doi: 10.1007/s13277-014-2845-5
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35 |
Idolo Tedesco, Gian Luigi Russo. Nonvitamin and Nonmineral Nutritional Supplements. 2019; : 251 doi: 10.1016/B978-0-12-812491-8.00036-9
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36 |
Alice S. T. Wong, Chi-Ming Che, Kar-Wah Leung. Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview. Natural Product Reports 2015; 32(2): 256 doi: 10.1039/C4NP00080C
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37 |
Hadi Zare-Zardini, Asghar Taheri-Kafrani, Ahmad Amiri, Abdol-Khalegh Bordbar. New generation of drug delivery systems based on ginsenoside Rh2-, Lysine- and Arginine-treated highly porous graphene for improving anticancer activity. Scientific Reports 2018; 8(1) doi: 10.1038/s41598-017-18938-y
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38 |
An-Sik Chung, Kyeong Mee Park. . Studies in Natural Products Chemistry 2016; 50: 131 doi: 10.1016/B978-0-444-63749-9.00004-9
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39 |
Shipeng Li, Wenfeng Han, Qichen He, Yang Wang, Gang Jin, Youcheng Zhang. Ginsenoside Rh2 suppresses colon cancer growth by targeting the miR-150-3p/SRCIN1/Wnt axis. Acta Biochimica et Biophysica Sinica 2023; 55(4): 633 doi: 10.3724/abbs.2023032
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40 |
Hyun-Jung Park, Hyun Soo Shim, Jeom Yong Kim, Joo Young Kim, Sun Kyu Park, Insop Shim. Ginseng Purified Dry Extract, BST204, Improved Cancer Chemotherapy-Related Fatigue and Toxicity in Mice. Evidence-Based Complementary and Alternative Medicine 2015; 2015: 1 doi: 10.1155/2015/197459
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41 |
Yingying Chen, Yuqiang Zhang, Wei Song, Ying Zhang, Xiu Dong, Mingqi Tan. Ginsenoside Rh2 Inhibits Migration of Lung Cancer Cells under Hypoxia via mir-491. Anti-Cancer Agents in Medicinal Chemistry 2019; 19(13): 1633 doi: 10.2174/1871520619666190704165205
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42 |
Xin Shi, Ji Yang, Gang Wei. Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through the Akt/GSK3β signaling pathway in human cervical cancer cells. Molecular Medicine Reports 2018; doi: 10.3892/mmr.2018.8454
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43 |
Xin-Ling He, Xiao-Huang Xu, Jia-Jie Shi, Mingqing Huang, Yitao Wang, Xiuping Chen, Jin-Jian Lu. Anticancer Effects of Ginsenoside Rh2: A Systematic Review. Current Molecular Pharmacology 2021; 15(1): 179 doi: 10.2174/1874467214666210309115105
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44 |
Zhiqing Yang, Tingting Zhao, Hongli Liu, Leida Zhang. Ginsenoside Rh2 inhibits hepatocellular carcinoma through β-catenin and autophagy. Scientific Reports 2016; 6(1) doi: 10.1038/srep19383
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45 |
Ying Qian, Rongrong Huang, Senlin Li, Rui Xie, Bei Qian, Zijun Zhang, Lei Li, Baotian Wang, Cheng Tian, Jian Yang, Ming Xiang. Ginsenoside Rh2 reverses cyclophosphamide-induced immune deficiency by regulating fatty acid metabolism. Journal of Leukocyte Biology 2019; 106(5): 1089 doi: 10.1002/JLB.2A0419-117R
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46 |
Jun Qian, Jing Li, Jian-Guang Jia, Xin Jin, Da-Jun Yu, Chen-Xu Guo, Bo Xie, Li-Yu Qian. Ginsenoside-Rh2 Inhibits Proliferation and Induces Apoptosis of Human Gastric Cancer SGC-7901 Side Population Cells. Asian Pacific Journal of Cancer Prevention 2016; 17(4): 1817 doi: 10.7314/APJCP.2016.17.4.1817
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47 |
Shaoyi Li, Wenchang Guo, Yun Gao, Yunhui Liu. Ginsenoside Rh2 inhibits growth of glioblastoma multiforme through mTor. Tumor Biology 2015; 36(4): 2607 doi: 10.1007/s13277-014-2880-2
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48 |
Shaoyi Li, Yun Gao, Weining Ma, Tianci Cheng, Yunhui Liu. Ginsenoside Rh2 inhibits invasiveness of glioblastoma through modulation of VEGF-A. Tumor Biology 2016; 37(12): 15477 doi: 10.1007/s13277-015-3759-6
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49 |
Dan Liu, Hao Wang, Zhangxu Zhou, Xiaohan Mao, Ziqian Ye, Zhilun Zhang, Shixin Tu, Yanlai Zhang, Xue Cai, Xin Lan, Zhang Zhang, Baoru Han, Guowei Zuo. Integrated bioinformatic analysis and experiment confirmation of the antagonistic effect and molecular mechanism of ginsenoside Rh2 in metastatic osteosarcoma. Journal of Pharmaceutical and Biomedical Analysis 2021; 201: 114088 doi: 10.1016/j.jpba.2021.114088
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50 |
Jin Hee Kim, Miseon Kim, Sun-Mi Yun, Seul Lee, Jae Hong No, Dong Hoon Suh, Kidong Kim, Yong Beom Kim. Ginsenoside Rh2 induces apoptosis and inhibits epithelial-mesenchymal transition in HEC1A and Ishikawa endometrial cancer cells. Biomedicine & Pharmacotherapy 2017; 96: 871 doi: 10.1016/j.biopha.2017.09.033
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51 |
Fei Gao, Jin-Ming Zhang, Zhan-Guo Wang, Wei Peng, Hui-Ling Hu, Chao-Mei Fu. Biotransformation, a Promising Technology for Anti-cancer Drug Development. Asian Pacific Journal of Cancer Prevention 2013; 14(10): 5599 doi: 10.7314/APJCP.2013.14.10.5599
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52 |
Sun Xiaodan, Cheng Ying. Role of ginsenoside Rh2 in tumor therapy and tumor microenvironment immunomodulation. Biomedicine & Pharmacotherapy 2022; 156: 113912 doi: 10.1016/j.biopha.2022.113912
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53 |
Ting Xia, Jin Zhang, Chuanxin Zhou, Yu Li, Wenhui Duan, Bo Zhang, Min Wang, Jianpei Fang. 20(S)-Ginsenoside Rh2 displays efficacy against T-cell acute lymphoblastic leukemia through the PI3K/Akt/mTOR signal pathway. Journal of Ginseng Research 2020; 44(5): 725 doi: 10.1016/j.jgr.2019.07.003
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54 |
Xia He, Ning Wang, Yu Zhang, Xiaobo Huang, Yi Wang. The therapeutic potential of natural products for treating pancreatic cancer. Frontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.1051952
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55 |
Benito Soto-Blanco. Herbal Biomolecules in Healthcare Applications. 2022; : 239 doi: 10.1016/B978-0-323-85852-6.00021-4
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56 |
QINGQIANG SHI, JING LI, ZIQIANG FENG, LVCUI ZHAO, LIAN LUO, ZHIMEI YOU, DANYANG LI, JING XIA, GUOWEI ZUO, DILONG CHEN. Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: Recruiting histone deacetylase and inhibiting activator protein 1 transcription factors. Molecular Medicine Reports 2014; 10(4): 1779 doi: 10.3892/mmr.2014.2392
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57 |
Alexander Popov, Anna Klimovich, Olga Styshova, Alexander Tsybulsky, Dmitry Hushpulian, Andrey Osipyants, Anna Khristichenko, Sergey Kazakov, Manuj Ahuja, Navneet Kaidery, Bobby Thomas, Vladimir Tishkov, Abraham Brown, Irina Gazaryan, Andrey Poloznikov. Probable Mechanisms of Doxorubicin Antitumor Activity Enhancement by Ginsenoside Rh2. Molecules 2022; 27(3): 628 doi: 10.3390/molecules27030628
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58 |
Guanqun Ge, Yan Yan, Hui Cai. Ginsenoside Rh2 Inhibited Proliferation by Inducing ROS Mediated ER Stress Dependent Apoptosis in Lung Cancer Cells. Biological & Pharmaceutical Bulletin 2017; 40(12): 2117 doi: 10.1248/bpb.b17-00463
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59 |
Lei Wu, Lin Bai, Wenshu Dai, Yaping Wu, Pengjun Xi, Jie Zhang, Lily Zheng. Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential
Therapeutic Applications. Current Topics in Medicinal Chemistry 2024; 24(10): 869 doi: 10.2174/0115680266283661240226052054
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