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For: Shi M, Yu DH, Chen Y, Zhao CY, Zhang J, Liu QH, Ni CR, Zhu MH. Expression of fibroblast activation protein in human pancreatic adenocarcinoma and its clinicopathological significance. World J Gastroenterol 2012; 18(8): 840-846 [PMID: 22371645 DOI: 10.3748/wjg.v18.i8.840]
URL: https://www.wjgnet.com/1007-9327/full/v18/i8/840.htm
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Number Citing Articles
1
Elizabeth K. Duperret, Aspen Trautz, Dylan Ammons, Alfredo Perales-Puchalt, Megan C. Wise, Jian Yan, Charles Reed, David B. Weiner. Alteration of the Tumor Stroma Using a Consensus DNA Vaccine Targeting Fibroblast Activation Protein (FAP) Synergizes with Antitumor Vaccine Therapy in Mice. Clinical Cancer Research 2018; 24(5) doi: 10.1158/1078-0432.CCR-17-2033
2
Peng Ruan, Zezhang Tao, Aili Tan. Low expression of miR-30a-5p induced the proliferation and invasion of oral cancer via promoting the expression of FAP. Bioscience Reports 2018; 38(1) doi: 10.1042/BSR20171027
3
Rita Saúde-Conde, Ayça Arçay Öztürk, Kosta Stosic, Oier Azurmendi Senar, Julie Navez, Christelle Bouchart, Tatjana Arsenijevic, Patrick Flamen, Jean-Luc Van Laethem. Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma or a Metaphor for Heterogeneity: From Single-Cell Analysis to Whole-Body Imaging. Biomedicines 2024; 12(3) doi: 10.3390/biomedicines12030591
4
Dongtang Yuan, Beibei Liu, Kaixiang Liu, Guotai Zhu, Zhitang Dai, Yue Xie. Overexpression of fibroblast activation protein and its clinical implications in patients with osteosarcoma. Journal of Surgical Oncology 2013; 108(3) doi: 10.1002/jso.23368
5
Yu Kato, Naoki Yamamoto, Yuichiro Uchida, Noriko Hiramatsu, Takato Ozeki, Yukari Minobe, Yukika Hasegawa, Sho Kawabe, Hikaru Yabuuchi, Seiji Yamada, Yuko Hata, Eiji Sugihara, Tetsuya Takimoto, Kuniaki Saito, Takeshi Takahara, Koichi Suda, Osamu Nagano, Hideyuki Saya. Rapid Drug Sensitivity Profiling via a Novel High-Success-Rate Culture Method for Patient-Derived Pancreatic Cancer: An Exploratory Preclinical Platform for Advancing Clinical Applications and Drug Development. Cells 2026; 15(4) doi: 10.3390/cells15040313
6
H Wang, Q Wu, Z Liu, X Luo, Y Fan, Y Liu, Y Zhang, S Hua, Q Fu, M Zhao, Y Chen, W Fang, X Lv. Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma. Cell Death & Disease 2014; 5(4) doi: 10.1038/cddis.2014.122
7
David Vetvicka, Ladislav Sivak, Chinmay M. Jogdeo, Raj Kumar, Rubayat Khan, Yu Hang, David Oupický. Gene silencing delivery systems for the treatment of pancreatic cancer: Where and what to target next?. Journal of Controlled Release 2021; 331 doi: 10.1016/j.jconrel.2021.01.020
8
Ryoichi Katsube, Kazuhiro Noma, Toshiaki Ohara, Noriyuki Nishiwaki, Teruki Kobayashi, Satoshi Komoto, Hiroaki Sato, Hajime Kashima, Takuya Kato, Satoru Kikuchi, Hiroshi Tazawa, Shunsuke Kagawa, Yasuhiro Shirakawa, Hisataka Kobayashi, Toshiyoshi Fujiwara. Fibroblast activation protein targeted near infrared photoimmunotherapy (NIR PIT) overcomes therapeutic resistance in human esophageal cancer. Scientific Reports 2021; 11(1) doi: 10.1038/s41598-021-81465-4
9
Martin Nurmik, Pit Ullmann, Fabien Rodriguez, Serge Haan, Elisabeth Letellier. In search of definitions: Cancer‐associated fibroblasts and their markers. International Journal of Cancer 2020; 146(4) doi: 10.1002/ijc.32193
10
Eliane Cortez, Pernilla Roswall, Kristian Pietras. Functional subsets of mesenchymal cell types in the tumor microenvironment. Seminars in Cancer Biology 2014; 25 doi: 10.1016/j.semcancer.2013.12.010
11
Katharina Dendl, Stefan A. Koerber, Clemens Kratochwil, Jens Cardinale, Rebecca Finck, Mardjan Dabir, Emil Novruzov, Tadashi Watabe, Vasko Kramer, Peter L. Choyke, Uwe Haberkorn, Frederik L. Giesel. FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis?. Cancers 2021; 13(19) doi: 10.3390/cancers13194946
12
Martijn A. van Dam, Floris A. Vuijk, Judith A. Stibbe, Ruben D. Houvast, Saskia A. C. Luelmo, Stijn Crobach, Shirin Shahbazi Feshtali, Lioe-Fee de Geus-Oei, Bert A. Bonsing, Cornelis F. M. Sier, Peter J. K. Kuppen, Rutger-Jan Swijnenburg, Albert D. Windhorst, Jacobus Burggraaf, Alexander L. Vahrmeijer, J. Sven D. Mieog. Overview and Future Perspectives on Tumor-Targeted Positron Emission Tomography and Fluorescence Imaging of Pancreatic Cancer in the Era of Neoadjuvant Therapy. Cancers 2021; 13(23) doi: 10.3390/cancers13236088
13
Felista L. Tansi, Andrea Schrepper, Michael Schwarzer, Ulf Teichgräber, Ingrid Hilger. Identifying the Morphological and Molecular Features of a Cell-Based Orthotopic Pancreatic Cancer Mouse Model during Growth over Time. International Journal of Molecular Sciences 2024; 25(11) doi: 10.3390/ijms25115619
14
Yafei Zhang, Mimi Xu, Yu Wang, Fang Yu, Xinxin Chen, Guangfa Wang, Kui Zhao, Hong Yang, Xinhui Su. Characteristics of 18F-FAPI-04 PET/CT in patients with peritoneal metastasis and to predict treatment efficacy, a head-to-head comparison with 18F-FDG PET/CT. Cancer Imaging 2025; 25(1) doi: 10.1186/s40644-025-00887-9
15
Qi Wang, Chang Song, Chunyan Zhao, Xiuyun Wei, Deli Li, Qinting Wu, Jing Li, Xiaomei Yang. Decoding tumors from fibroblast activation protein: A review of the latest diagnostic and therapeutic prospects. International Journal of Biological Macromolecules 2025; 318 doi: 10.1016/j.ijbiomac.2025.145006
16
Hiromitsu Maehira, Toru Miyake, Hiroya Iida, Aya Tokuda, Haruki Mori, Daiki Yasukawa, Ken-ichi Mukaisho, Tomoharu Shimizu, Masaji Tani. Vimentin Expression in Tumor Microenvironment Predicts Survival in Pancreatic Ductal Adenocarcinoma: Heterogeneity in Fibroblast Population. Annals of Surgical Oncology 2019; 26(13) doi: 10.1245/s10434-019-07891-x
17
Yuriko Mori, Katharina Dendl, Emil Novruzov, Stefan Körber, Frederik L. Giesel. PET/CT-Atlas. 2024;  doi: 10.1007/978-3-662-67192-4_31
18
Yanghongyan Jiang, Yaxin Tian, Bei Feng, Tingting Zhao, Liang Du, Xiaodong Yu, Qian Zhao. A novel molecular imaging probe [99mTc]Tc-HYNIC-FAPI targeting cancer-associated fibroblasts. Scientific Reports 2023; 13(1) doi: 10.1038/s41598-023-30806-6
19
William McGahan, Alexa Chadwick, Karen Lindsay, Brook Gulhane, Melissa J. Latter, Thomas ORourke, Paul A. Thomas, David Cavallucci. 68 Ga-FAPI PET/CT Prevents Futile Surgery and Demonstrates Tumor Biology in Patients with Pancreatic Ductal Adenocarcinoma . Journal of Nuclear Medicine 2025; 66(12) doi: 10.2967/jnumed.125.270510
20
Paula E. Borgonje, Louise M. Andrews, Gerarda J. M. Herder, John M. H. de Klerk. Performance and Prospects of [68Ga]Ga-FAPI PET/CT Scans in Lung Cancer. Cancers 2022; 14(22) doi: 10.3390/cancers14225566
21
Martin C. Whittle, Sunil R. Hingorani. Fibroblasts in Pancreatic Ductal Adenocarcinoma: Biological Mechanisms and Therapeutic Targets. Gastroenterology 2019; 156(7) doi: 10.1053/j.gastro.2018.12.044
22
Naomi Yamamoto, Stephanie Dobersch, Ian Loveless, Annie N. Samraj, Gun Ho Jang, Miki Haraguchi, Liang-I. Kang, Marianna B. Ruzinova, Kiran R. Vij, Jacqueline L. Mudd, Thomas Walsh, Rachael A. Safyan, Elena Gabriela Chiorean, Sunil R. Hingorani, Nathan M. Bolton, Li Li, Ryan C. Fields, David G. DeNardo, Faiyaz Notta, Howard C. Crawford, Nina G. Steele, Sita Kugel. HMGA2 Expression Predicts Subtype, Survival, and Treatment Outcome in Pancreatic Ductal Adenocarcinoma. Clinical Cancer Research 2025; 31(4) doi: 10.1158/1078-0432.CCR-24-2200
23
Stephanie L. Slania, Deepankar Das, Ala Lisok, Yong Du, Zirui Jiang, Ronnie C. Mease, Steven P. Rowe, Sridhar Nimmagadda, Xing Yang, Martin G. Pomper. Imaging of Fibroblast Activation Protein in Cancer Xenografts Using Novel (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine-Based Small Molecules. Journal of Medicinal Chemistry 2021; 64(7) doi: 10.1021/acs.jmedchem.0c02171
24
Adéla Šimková, Petr Bušek, Aleksi Šedo, Jan Konvalinka. Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2020; 1868(7) doi: 10.1016/j.bbapap.2020.140409
25
Zhipeng Li, Jiao Xu, Chan Li, Jianliang Shen, Bo Peng. A FAP-α-activatable near-infrared theranostic probe for fluorescence imaging of pancreatic cancer and potent in vitro photodynamic activity. Bioorganic Chemistry 2026; 168 doi: 10.1016/j.bioorg.2025.109326
26
Cheng Xie, Jing-Jie Wu, Yurong Feng, Tian-Bing Ren, Lin Yuan, Shuang-Yan Huan, Xiao-Bing Zhang. FAPα-Activated NIR-I Fluorescent Probe with Improved Water Solubility for Tumor Imaging. Analytical Chemistry 2026; 98(6) doi: 10.1021/acs.analchem.5c07190
27
Jean Albrengues, Isabelle Bourget, Catherine Pons, Vincent Butet, Paul Hofman, Sophie Tartare-Deckert, Chloe C. Feral, Guerrino Meneguzzi, Cedric Gaggioli. LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer. Cell Reports 2014; 7(5) doi: 10.1016/j.celrep.2014.04.036
28
Katie Brake, Audifás-Salvador Matus-Meza, Purnima Rawat, Pedram Rikhtechi, Kiana Sherkat Sadi, Jered C. Garrison. Exploration of the utilization of irreversible cysteine protease inhibitor in FAP-targeted radiopharmaceuticals design to increase tumor residence time. Nuclear Medicine and Biology 2025;  doi: 10.1016/j.nucmedbio.2025.109031
29
Amir Savardashtaki, Zahra Shabaninejad, Ahmad Movahedpour, Roxana Sahebnasagh, Hamed Mirzaei, Michael R Hamblin. MiRNAs Derived from Cancer-Associated Fibroblasts in Colorectal Cancer. Epigenomics 2019; 11(14) doi: 10.2217/epi-2019-0110
30
Jiefu Jin, James D. Barnett, Balaji Krishnamachary, Yelena Mironchik, Catherine K. Luo, Hisataka Kobayashi, Zaver M. Bhujwalla. Evaluating near‐infrared photoimmunotherapy for targeting fibroblast activation protein‐α expressing cells in vitro and in vivo. Cancer Science 2023; 114(1) doi: 10.1111/cas.15601
31
Xinying Hu, Tao Zhou, Jiazhong Ren, Jinghao Duan, Hongbo Wu, Xiaoli Liu, Zhengshuai Mu, Ning Liu, Yuchun Wei, Shuanghu Yuan. Response Prediction Using18F-FAPI-04 PET/CT in Patients with Esophageal Squamous Cell Carcinoma Treated with Concurrent Chemoradiotherapy. Journal of Nuclear Medicine 2023; 64(4) doi: 10.2967/jnumed.122.264638
32
Cole R. Drifka, Agnes G. Loeffler, Kara Mathewson, Adib Keikhosravi, Jens C. Eickhoff, Yuming Liu, Sharon M. Weber, W. John Kao, Kevin W. Eliceiri. Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection. Oncotarget 2016; 7(46) doi: 10.18632/oncotarget.12772
33
Yongchen Ma, Jing Zhu, Shanwen Chen, Tengyu Li, Ju Ma, Shihao Guo, Jianwen Hu, Taohua Yue, Junling Zhang, Pengyuan Wang, Xin Wang, Guowei Chen, Yucun Liu. Activated gastric cancer-associated fibroblasts contribute to the malignant phenotype and 5-FU resistance via paracrine action in gastric cancer. Cancer Cell International 2018; 18(1) doi: 10.1186/s12935-018-0599-7
34
Majid Janani, Amirhoushang Poorkhani, Mirmohammadhosseinaali Sharifiandavaei, Zahra Akbari, Khalil Pourkhalili, Saeed Golfiroozi, Taghi Amiriani, Arash Tahmasebifar, Farahnazsadat Ahmadi, Yalda Jorjanisorkhankalateh, Morad Roudbaraki, Vahid Khori, Ali Mohammad Alizadeh. Predicting fibroblast activation protein overexpression in the overall survival rate of cancer patients: a systematic review and meta-analysis. Systematic Reviews 2025; 14(1) doi: 10.1186/s13643-025-02929-6
35
Yurong Feng, Cheng Xie, Tian‐Bing Ren, Shuai Xu, Shulin Huang, Su‐Lai Liu, Lin Yuan, Shuang‐Yan Huan, Xiao‐Bing Zhang. A General Strategy to Develop Highly Sensitive FAPα Fluorescent Probes for Invasive Cancer Detection. Angewandte Chemie International Edition 2025; 64(41) doi: 10.1002/anie.202512588
36
Jie Ding, Jiangdong Qiu, Zhixin Hao, Hua Huang, Qiaofei Liu, Wenjing Liu, Chao Ren, Marcus Hacker, Taiping Zhang, Wenming Wu, Li Huo, Xiang Li. Prognostic value of preoperative [68 Ga]Ga-FAPI-04 PET/CT in patients with resectable pancreatic ductal adenocarcinoma in correlation with immunohistological characteristics. European Journal of Nuclear Medicine and Molecular Imaging 2023; 50(6) doi: 10.1007/s00259-022-06100-4
37
CUIXIA CAI, RONG SHI, YUAN GAO, JUN ZENG, MIN WEI, HANDUO WANG, WENLING ZHENG, WENLI MA. Reduced expression of sushi domain containing 2 is associated with progression of non-small cell lung cancer. Oncology Letters 2015; 10(6) doi: 10.3892/ol.2015.3737
38
Sophie C. Siegmund, Rudolf A. Werner, Frederik L. Giesel. Fibroblast Activation Protein. PET Clinics 2026; 21(3) doi: 10.1016/j.cpet.2026.02.004
39
Chao Zeng, Ming Wen, Xiaomei Liu. Fibroblast activation protein in osteosarcoma cells promotes angiogenesis via AKT and ERK signaling pathways. Oncology Letters 2018;  doi: 10.3892/ol.2018.8027
40
Boju Pan, Quan Liao, Zheyu Niu, Li Zhou, Yupei Zhao. Cancer-Associated Fibroblasts in Pancreatic Adenocarcinoma. Future Oncology 2015; 11(18) doi: 10.2217/fon.15.176
41
Hyunjin Park, Yangkyu Lee, Hyejung Lee, Jin-Won Kim, Jin-Hyeok Hwang, Jaihwan Kim, Yoo-Seok Yoon, Ho-Seong Han, Haeryoung Kim. The prognostic significance of cancer-associated fibroblasts in pancreatic ductal adenocarcinoma. Tumor Biology 2017; 39(10) doi: 10.1177/1010428317718403
42
Daphne N. Dorst, Esther M. M. Smeets, Christian Klein, Cathelijne Frielink, Daan Geijs, Marija Trajkovic-Arsic, Phyllis F. Y. Cheung, Martijn W. J. Stommel, Martin Gotthardt, Jens T. Siveke, Erik H. J. G. Aarntzen, Sanne A. M. van Lith. Fibroblast Activation Protein-Targeted Photodynamic Therapy of Cancer-Associated Fibroblasts in Murine Models for Pancreatic Ductal Adenocarcinoma. Molecular Pharmaceutics 2023; 20(8) doi: 10.1021/acs.molpharmaceut.3c00453
43
Jun Yu, Yuan Pan, Yi Chen, Zhihui Shu, Lin Ma, Bin Wu, Jingdong Li, Jianshui Li, Chuan Lan. High SOX17 expression is correlated with favorable prognosis and CD8(+) TILs expression in patients with pancreatic cancer after curative resection. Translational Oncology 2026; 70 doi: 10.1016/j.tranon.2026.102859
44
Bailee H. Sliker, Paul M. Campbell. Fibroblasts Influence the Efficacy, Resistance, and Future Use of Vaccines and Immunotherapy in Cancer Treatment. Vaccines 2021; 9(6) doi: 10.3390/vaccines9060634
45
Mohammad Javad Mousavi, Jafar Karami, Masoumeh Alimohammadi, Farid Solaymani-Mohammadi, Nima Rezaei. Handbook of Cancer and Immunology. 2023;  doi: 10.1007/978-3-030-80962-1_357-1
46
Jiajia Tang, Quan Zheng, Qi Wang, Yaru Zhao, Preeta Ananthanarayanan, Chiara Reina, Berina Šabanović, Ke Jiang, Ming-Hsin Yang, Clara Csilla Meny, Huimin Wang, Mette Ø. Agerbaek, Thomas Mandel Clausen, Tobias Gustavsson, Chenlei Wen, Felice Borghi, Alfredo Mellano, Elisabetta Fenocchio, Vanesa Gregorc, Anna Sapino, Thor G. Theander, Da Fu, Alexandra Aicher, Ali Salanti, Baiyong Shen, Christopher Heeschen. CTC-derived pancreatic cancer models serve as research tools and are suitable for precision medicine approaches. Cell Reports Medicine 2024; 5(9) doi: 10.1016/j.xcrm.2024.101692
47
Yuriko Mori, Emil Novruzov, Dominik Schmitt, Jens Cardinale, Tadashi Watabe, Peter L. Choyke, Abass Alavi, Uwe Haberkorn, Frederik L. Giesel. Clinical applications of fibroblast activation protein inhibitor positron emission tomography (FAPI-PET). npj Imaging 2024; 2(1) doi: 10.1038/s44303-024-00053-z
48
Jorge D. Oldan, Anurag Anugu, Md Zobaer Islam, Alireza Amindarolzarbi, Rudolf A. Werner, Martin G. Pomper, Lilja B. Solnes, Frankis Almaguel, Stergios Moschos, Benjamin L Viglianti, Steven P. Rowe. Theranostics 2.0: Target-driven, artificial intelligence-enabled cancer therapy across tumor types. Diagnostic and Interventional Imaging 2025; 106(12) doi: 10.1016/j.diii.2025.07.003
49
D. V. Tyulkina, V. V. Pleshkan, I. V. Alekseenko, M. R. Kopantseva, E. D. Sverdlov. Expression of the FAP gene in non-fibroblast human cell lines. Development of cancer-associated fibroblast models. Doklady Biochemistry and Biophysics 2016; 470(1) doi: 10.1134/S1607672916050033
50
Dapeng Sun, Wen Li, Dongyang Ding, Kunjiang Tan, Wenbin Ding, Zongyan Wang, Siyuan Fu, Guojun Hou, Wei-ping Zhou, Fangming Gu. IL-17a promotes hepatocellular carcinoma by increasing FAP expression in hepatic stellate cells via activation of the STAT3 signaling pathway. Cell Death Discovery 2024; 10(1) doi: 10.1038/s41420-024-01995-4
51
Majid Janani, Amirhoushang Poorkhani, Taghi Amiriani, Ghazaleh Donyadideh, Farahnazsadat Ahmadi, Yalda Jorjanisorkhankalateh, Fereshteh Beheshti-Nia, Zahra Kalaei, Morad Roudbaraki, Mahsa Soltani, Vahid Khori, Ali Mohammad Alizadeh. Association of future cancer metastases with fibroblast activation protein-α: a systematic review and meta-analysis. Frontiers in Oncology 2024; 14 doi: 10.3389/fonc.2024.1339050
52
Mohammad Javad Mousavi, Jafar Karami, Masoumeh Alimohammadi, Farid Solaymani-Mohammadi, Nima Rezaei. Cancer and Surrounding Environment. Handbook of Cancer and Immunology 2025; 3 doi: 10.1007/978-3-032-00761-2_357
53
Richard P. Baum, Emil Novruzov, Tianzhi Zhao, Lukas Greifenstein, Vivianne Jakobsson, Elisabetta Perrone, Aditi Mishra, Aleksandr Eismant, Kriti Ghai, Ortwin Klein, Bastian Jaeschke, Daniel Benz-Zils, Jens Cardinale, Yuriko Mori, Frederik L. Giesel, Jingjing Zhang. Radiomolecular Theranostics With Fibroblast-Activation-Protein Inhibitors and Peptides. Seminars in Nuclear Medicine 2024; 54(4) doi: 10.1053/j.semnuclmed.2024.05.010
54
Han Ren, Xiang-Zhong Zeng, Xiao-Xiao Zhao, Da-yong Hou, Haodong Yao, Muhammad Yaseen, Lina Zhao, Wan-hai Xu, Hao Wang, Li-Li Li. A bioactivated in vivo assembly nanotechnology fabricated NIR probe for small pancreatic tumor intraoperative imaging. Nature Communications 2022; 13(1) doi: 10.1038/s41467-021-27932-y
55
Liqiang Liu, Sicheng Xu, Pengbiao Miao, Xing He, Yaorong Peng, Qixian Zhou, Junkai Ren, Zhenyu Zhou, Huilin Ye, Wenbin Li. Extracellular Volume Fraction Combined With Pathological Features of α‐SMA and FAP for Predicting the Prognosis of Patients With Pancreatic Ductal Adenocarcinoma After Surgery and Evaluating the Efficacy of Chemotherapy. Cancer Medicine 2025; 14(19) doi: 10.1002/cam4.71281
56
Dengsai Peng, Jing He, Hanxiang Liu, Jianpeng Cao, Yingwei Wang, Yue Chen. FAPI PET/CT research progress in digestive system tumours. Digestive and Liver Disease 2022; 54(2) doi: 10.1016/j.dld.2021.07.011
57
Jo Kurosawa, Katsunobu Tawada, Rintaro Mikata, Takeshi Ishihara, Toshio Tsuyuguchi, Masayoshi Saito, Ryota Shimofusa, Hideyuki Yoshitomi, Masayuki Ohtsuka, Masaru Miyazaki, Osamu Yokosuka. Prognostic relevance of apparent diffusion coefficient obtained by diffusion‐weighted MRI in pancreatic cancer. Journal of Magnetic Resonance Imaging 2015; 42(6) doi: 10.1002/jmri.24939
58
Emil Novruzov, Frederik L. Giesel, Yuriko Mori, Peter L. Choyke, Mardjan Dabir, Eduards Mamlins, Dominik Schmitt, Christina Antke, Claudio Pinto, Cristian Soza-Ried, Rene Fernandez, Horacio Amaral, Vasko Kramer, Leonardo Badinez. Head-to-Head Intra-Individual Comparison of Biodistribution and Tumor Uptake of [18F]FAPI-74 with [18F]FDG in Patients with PDAC: A Prospective Exploratory Study. Cancers 2023; 15(10) doi: 10.3390/cancers15102798
59
Chien-shan Cheng, Pei-wen Yang, Yun Sun, Shao-li Song, Zhen Chen. Fibroblast activation protein-based theranostics in pancreatic cancer. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.969731
60
Yaqing Zhao, Jiazhong Ren. 18F-FAPI-04 PET/CT parameters predict PD-L1 expression in esophageal squamous cell carcinoma. Frontiers in Immunology 2023; 14 doi: 10.3389/fimmu.2023.1266843
61
Yentl Van Rymenant, Anke de Groot, Laura Dirkx, Emile Verhulst, Joni De Loose, Isabel Pintelon, Tias Verhezen, Jorrit De Waele, Sofie Thys, Olivier De Wever, Muhammet Tanc, Guy Caljon, Pieter Van der Veken, Ingrid De Meester. Fibroblast activation protein on human natural killer cells: insights from natural killer cell activation and crosstalk with cancer-associated fibroblasts. Journal of Leukocyte Biology 2025; 117(7) doi: 10.1093/jleuko/qiaf103
62
Ahmed K. AL-TIMEEMI, Alzahraa I. AL-TIMEEMI, Jasim AL-IBRAHEEMI, Majid ASSADI, Habibollah DADGAR, Hossein ARABI, Habib ZAIDI. Imaging tumor microenvironment: clinical experience with 68Ga-FAPI PET/CT across multiple cancer types. The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2026; 70(2) doi: 10.23736/S1824-4785.26.03673-3
63
Ting Yu, Li Gong, Wei Li, Qianfei Zuo, Dongping Cai, Hui Mao, Lina Wang, Jie Lin, Bin Xiao. MiR-30a suppresses metastasis of gastric adenocarcinoma via targeting FAPα. Cancer Biomarkers 2020; 27(4) doi: 10.3233/CBM-190314
64
Zhaoye Wu, Yuqi Hua, Qiaoling Shen, Chunjing Yu. Research progress on the role of fibroblast activation protein in diagnosis and treatment of cancer. Nuclear Medicine Communications 2022; 43(7) doi: 10.1097/MNM.0000000000001565
65
Iris J. M. Levink, Malgorzata I. Srebniak, Walter G. De Valk, Monique M. van Veghel-Plandsoen, Anja Wagner, Djuna L. Cahen, Gwenny M. Fuhler, Marco J. Bruno. An 8q24 Gain in Pancreatic Juice Is a Candidate Biomarker for the Detection of Pancreatic Cancer. International Journal of Molecular Sciences 2023; 24(6) doi: 10.3390/ijms24065097
66
Hannelore Ceuppens, Kirsten De Ridder, Thomas Ertveldt, Katty Zeven, Wout De Mey, Ana Rita Pombo Antunes, Laurent Navarro, Nina Dumauthioz, Tony Lahoutte, Jens M. Debacker, Nick Devoogdt, Marleen Keyaerts, Matthias D’Huyvetter, Cleo Goyvaerts, Karine Breckpot. Immune modulation following α and β − radionuclide therapy targeting fibroblast activation protein-α in a preclinical tumor model . OncoImmunology 2025; 14(1) doi: 10.1080/2162402X.2025.2540054
67
Emil Novruzov, Frederik L. Giesel, Eduards Mamlins, Tadashi Watabe, Jens Cardinale, Christina Antke, Yuriko Mori, Nils Schupps, Claudio Pinto, Cristian Soza-Ried, Rene Fernandez, Horacio Amaral, Vasko Kramer, Leonardo Badinez. The analysis of biodistribution and tumor uptake of [18F]AlF-FAPI-74 in patients with soft tissue sarcoma and gastro-intestinal tumors compared with [18F]FDG in a prospective, exploratory study. EJNMMI Reports 2026; 10(1) doi: 10.1186/s41824-026-00295-7
68
Lei Xin, Jinfang Gao, Ziliang Zheng, Yiyou Chen, Shuxin Lv, Zhikai Zhao, Chunhai Yu, Xiaotang Yang, Ruiping Zhang. Fibroblast Activation Protein-α as a Target in the Bench-to-Bedside Diagnosis and Treatment of Tumors: A Narrative Review. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.648187
69
Paulette Mhawech-Fauceglia, Li Yan, Maryam Sharifian, Xing Ren, Song Liu, Grace Kim, Simon A. Gayther, Tanja Pejovic, Kate Lawrenson. Stromal Expression of Fibroblast Activation Protein Alpha (FAP) Predicts Platinum Resistance and Shorter Recurrence in patients with Epithelial Ovarian Cancer. Cancer Microenvironment 2015; 8(1) doi: 10.1007/s12307-014-0153-7
70
Paulette Mhawech-Fauceglia, Dan Wang, Damanzoopinder Samrao, Grace Kim, Kate Lawrenson, Teodulo Meneses, Song Liu, Annie Yessaian, Tanja Pejovic. Clinical Implications of Marker Expression of Carcinoma-Associated Fibroblasts (CAFs) in Patients with Epithelial Ovarian Carcinoma After Treatment with Neoadjuvant Chemotherapy. Cancer Microenvironment 2014; 7(1-2) doi: 10.1007/s12307-013-0140-4
71
Lizzia Raffaghello, Francesco Dazzi. Classification and biology of tumour associated stromal cells. Immunology Letters 2015; 168(2) doi: 10.1016/j.imlet.2015.06.016
72
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