| For: | Gwak GY, Moon TG, Lee DH, Yoo BC. Glycyrrhizin attenuates HMGB1-induced hepatocyte apoptosis by inhibiting the p38-dependent mitochondrial pathway. World J Gastroenterol 2012; 18(7): 679-684 [PMID: 22363140 DOI: 10.3748/wjg.v18.i7.679] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v18/i7/679.htm |
| Number | Citing Articles |
| 1 |
Nada F. Abo El-Magd, Amro El-Karef, Mamdouh M. El-Shishtawy, Laila A. Eissa. Hepatoprotective effects of glycyrrhizin and omega-3 fatty acids on Nuclear Factor-kappa B pathway in thioacetamide-induced fibrosis in rats. Egyptian Journal of Basic and Applied Sciences 2015; 2(2) doi: 10.1016/j.ejbas.2014.12.005
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| 2 |
Wenqiang Han, Wenxin Wang, Qinhong Wang, Kellina Maduray, Li Hao, Jingquan Zhong. A review on regulation of DNA methylation during post-myocardial infarction. Frontiers in Pharmacology 2024; 15 doi: 10.3389/fphar.2024.1267585
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| 3 |
Wei Dong, Min Zhang, Yaxi Zhu, Yuanhan Chen, Xingchen Zhao, Ruizhao Li, Li Zhang, Zhiming Ye, Xingling Liang. Protective effect of NSA on intestinal epithelial cells in a necroptosis model. Oncotarget 2017; 8(49) doi: 10.18632/oncotarget.21418
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| 4 |
Kasha P. Singh, Laura J. Pallett, Harsimran Singh, Antony Chen, Itziar Otano, Marion Duriez, Krista Rombouts, Massimo Pinzani, Megan Crane, Giuseppe Fusai, Anchalee Avihingsanon, Sharon R. Lewin, Mala K. Maini. Pro-fibrogenic role of alarmin high mobility group box 1 in HIV–hepatitis B virus coinfection. AIDS 2023; 37(3) doi: 10.1097/QAD.0000000000003435
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| 5 |
Jinjin Yu, Huiheng Qu, Weicheng Xu, Yiming Fang, Nan Wang, Wei Shi. Mechanisms and therapeutic potential of glycyrrhizic acid: Insights into key signaling pathways and disease modulation (Review). Molecular Medicine Reports 2026; 33(5) doi: 10.3892/mmr.2026.13836
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| 6 |
Zhigang Chang, Yongqing Li, Wei He, Baoling Liu, Ihab Halaweish, Ted Bambakidis, Yingjian Liang, Hasan B. Alam. Selective inhibition of histone deacetylase 6 promotes survival in a rat model of hemorrhagic shock. Journal of Trauma and Acute Care Surgery 2015; 79(6) doi: 10.1097/TA.0000000000000784
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| 7 |
Deepak Kumar Semwal, Ankit Kumar, Ruchi Badoni Semwal, Nand Kishor Dadhich, Ashutosh Chauhan, Vineet Kumar. Glycyrrhizin (Glycyrrhizic Acid)—Pharmacological Applications and Associated Molecular Mechanisms. Drugs and Drug Candidates 2025; 4(4) doi: 10.3390/ddc4040044
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| 8 |
Yanli Sun, Xiaolong Shu, Fei Guo.
ALKBH5-Mediated m
6
A Demethylation Stabilizes HMGB1 to Drive Hepatocyte Pyroptosis and Liver Injury in Heat Stroke: Targeting via Biomimetic Nanodelivery
. Antioxidants & Redox Signaling 2026; doi: 10.1177/15230864261449248
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| 9 |
Rhian Stavely, Lauren Sahakian, Rhiannon T. Filippone, Vanesa Stojanovska, Joel C. Bornstein, Samy Sakkal, Kulmira Nurgali. Oxidative Stress-Induced HMGB1 Translocation in Myenteric Neurons Contributes to Neuropathy in Colitis. Biomolecules 2022; 12(12) doi: 10.3390/biom12121831
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| 10 |
Kil‐Jung Kim, Jae‐Sun Choi, Kyu‐Won Kim, Joo‐Won Jeong. The Anti‐Angiogenic Activities of Glycyrrhizic Acid in Tumor Progression. Phytotherapy Research 2013; 27(6) doi: 10.1002/ptr.4800
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| 11 |
Gu Gong, Lei Xiang, Libang Yuan, Ling Hu, Wei Wu, Lin Cai, Liang Yin, Hailong Dong, Ronald J. Korthuis. Protective Effect of Glycyrrhizin, a Direct HMGB1 Inhibitor, on Focal Cerebral Ischemia/Reperfusion-Induced Inflammation, Oxidative Stress, and Apoptosis in Rats. PLoS ONE 2014; 9(3) doi: 10.1371/journal.pone.0089450
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| 12 |
Xu Wu, Wenyu Gu, Huan Lu, Chengying Liu, Biyun Yu, Hui Xu, Yaodong Tang, Shanqun Li, Jian Zhou, Chuan Shao, Hariom Yadav. Soluble Receptor for Advanced Glycation End Product Ameliorates Chronic Intermittent Hypoxia Induced Renal Injury, Inflammation, and Apoptosis via P38/JNK Signaling Pathways. Oxidative Medicine and Cellular Longevity 2016; 2016(1) doi: 10.1155/2016/1015390
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| 13 |
Xing Lai, Junhua Gong, Weiming Wang, Ding Cao, Menghao Wang, Yiming Liu, Hao Wu, Yakun Wu, Yong Chen, Zhong Zeng, Jinzheng Li, Jianping Gong. Acetyl‐3‐Aminoethyl Salicylate Ameliorates Hepatic Ischemia/Reperfusion Injury and Liver Graft Survival Through a High‐Mobility Group Box 1/Toll‐Like Receptor 4–Dependent Mechanism. Liver Transplantation 2019; 25(8) doi: 10.1002/lt.25575
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| 14 |
Domenica Musumeci, Giovanni N. Roviello, Daniela Montesarchio. An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies. Pharmacology & Therapeutics 2014; 141(3) doi: 10.1016/j.pharmthera.2013.11.001
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| 15 |
Yihua Zhang, Hui Li, Xueli Liu, Qiang Wang, Dong Zhao, Ming Su, Zhixin Jia, Shigang Shen. Integrating Metabolomics and Network Pharmacology to Decipher the Hepatoprotective Effect Mechanisms of Magnesium Isoglycyrrhizinate Injection. Current Issues in Molecular Biology 2023; 46(1) doi: 10.3390/cimb46010019
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| 16 |
Bo Liang, Xiao-Ling Guo, Jing Jin, Yong-Chun Ma, Zheng-Quan Feng. Glycyrrhizic acid inhibits apoptosis and fibrosis in carbon-tetrachloride-induced rat liver injury. World Journal of Gastroenterology 2015; 21(17): 5271-5280 doi: 10.3748/wjg.v21.i17.5271
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| 17 |
Haoran Zhong, Xiang Gui, Ling Hou, Rongxue Lv, Yamei Jin. From Inflammation to Fibrosis: Novel Insights into the Roles of High Mobility Group Protein Box 1 in Schistosome-Induced Liver Damage. Pathogens 2022; 11(3) doi: 10.3390/pathogens11030289
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| 18 |
Wei Wang, Feng Zhao, Yong Fang, Xiantao Li, Lei Shen, Tongwa Cao, Hechen Zhu. Glycyrrhizin protects against porcine endotoxemia through modulation of systemic inflammatory response. Critical Care 2013; 17(2) doi: 10.1186/cc12558
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| 19 |
Florent Duval, Jorge E. Moreno-Cuevas, Maria Teresa González-Garza, Carlos Rodríguez-Montalvo, Delia Elva Cruz-Vega. Liver Fibrosis and Protection Mechanisms Action of Medicinal Plants Targeting Apoptosis of Hepatocytes and Hepatic Stellate Cells. Advances in Pharmacological Sciences 2014; 2014 doi: 10.1155/2014/373295
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| 20 |
Dénes Kleiner, Gabriella Hegyi, Rudolf Urbanics, László Dézsi, Hermina Robotka, Erzsébet Fehér, Éva Sárdi, János Szebeni, Anna Blázovics. Hepatoprotective liposomal glycyrrhizin in alcoholic liver injury. European Journal of Integrative Medicine 2016; 8 doi: 10.1016/j.eujim.2016.11.005
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| 21 |
Cedric Stephan Graebin. Sweeteners. Reference Series in Phytochemistry 2018; doi: 10.1007/978-3-319-27027-2_15
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| 22 |
Yuqin Li, Qiu Chen, Wei Ji, Ying Ding, Weifang Zhou. HMGB1 Binding to the RAGE Receptor Contributes to the Pathogenesis of Asthma. Pediatric Allergy, Immunology, and Pulmonology 2018; 31(3) doi: 10.1089/ped.2017.0846
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| 23 |
X. Xu, H. Zhu, T. Wang, Y. Sun, P. Ni, Y. Liu, S. Tian, P. Amoah Barnie, H. Shen, W. Xu, H. Xu, Z. Su. Exogenous High‐Mobility Group Box 1 Inhibits Apoptosis and Promotes the Proliferation of Lewis Cells via RAGE/TLR4‐Dependent Signal Pathways. Scandinavian Journal of Immunology 2014; 79(6) doi: 10.1111/sji.12174
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| 24 |
Moon-Sun Kim, Madeleine Ong, Xianqin Qu. Optimal management for alcoholic liver disease: Conventional medications, natural therapy or combination?. World Journal of Gastroenterology 2016; 22(1): 8-23 doi: 10.3748/wjg.v22.i1.8
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| 25 |
Liang Chen, Chun Hu, Molly Hood, Juntao Kan, Xiaona Gan, Xue Zhang, Yi Zhang, Jun Du. An Integrated Approach Exploring the Synergistic Mechanism of Herbal Pairs in a Botanical Dietary Supplement: A Case Study of a Liver Protection Health Food. International Journal of Genomics 2020; 2020 doi: 10.1155/2020/9054192
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| 26 |
Noha M. Shafik, Rasha Osama El-Esawy, Darin A. Mohamed, Ehsan A. Deghidy, Omnia Safwat El-Deeb. Regenerative effects of glycyrrhizin and/or platelet rich plasma on type-II collagen induced arthritis: Targeting autophay machinery markers, inflammation and oxidative stress. Archives of Biochemistry and Biophysics 2019; 675 doi: 10.1016/j.abb.2019.108095
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| 27 |
Mahmoud Orazizadeh, Fereshtesadat Fakhredini, Esrafil Mansouri, Layasadat Khorsandi. Effect of glycyrrhizic acid on titanium dioxide nanoparticles-induced hepatotoxicity in rats. Chemico-Biological Interactions 2014; 220 doi: 10.1016/j.cbi.2014.07.001
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| 28 |
Yuri Cho, Jung-Hwan Yoon, Jeong-ju Yoo, Minjong Lee, Dong Hyeon Lee, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Yoon Jun Kim, Chung Yong Kim. Fucoidan protects hepatocytes from apoptosis and inhibits invasion of hepatocellular carcinoma by up-regulating p42/44 MAPK-dependent NDRG-1/CAP43. Acta Pharmaceutica Sinica B 2015; 5(6) doi: 10.1016/j.apsb.2015.09.004
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| 29 |
Yibo Liu, Wenfang Guo, Minhui Li. Diammonium Glycyrrhizinate Preparation for Liver Function Recovery in Chronic
Hepatitis B in China: A Meta-analysis with Trial Sequential Analysis. Current Pharmaceutical Design 2022; 28(25) doi: 10.2174/1381612828666220421134910
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| 30 |
Rajarshi Sil, Doel Ray, Abhay Sankar Chakraborti. Glycyrrhizin ameliorates metabolic syndrome-induced liver damage in experimental rat model. Molecular and Cellular Biochemistry 2015; 409(1-2) doi: 10.1007/s11010-015-2523-y
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| 31 |
Ke Xiang, Long Cheng, Zhulin Luo, Jiandong Ren, Fuzhou Tian, Lijun Tang, Tao Chen, Ruiwu Dai, Zoltan Rakonczay. Glycyrrhizin Suppresses the Expressions of HMGB1 and Relieves the Severity of Traumatic Pancreatitis in Rats. PLoS ONE 2014; 9(12) doi: 10.1371/journal.pone.0115982
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| 32 |
Seidu A. Richard, Marian Sackey, Zhaoliang Su, Huaxi Xu. Pivotal neuroinflammatory and therapeutic role of high mobility group box 1 in ischemic stroke. Bioscience Reports 2017; 37(6) doi: 10.1042/BSR20171104
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| 33 |
Chenyan Li, Shiqiao Peng, Xin Liu, Cheng Han, Xinyi Wang, Ting Jin, Shanshan Liu, Weiwei Wang, Xiaochen Xie, Xue He, Hanyi Zhang, Ling Shan, Chenling Fan, Zhongyan Shan, Weiping Teng. Glycyrrhizin, a Direct HMGB1 Antagonist, Ameliorates Inflammatory Infiltration in a Model of Autoimmune Thyroiditis via Inhibition of TLR2-HMGB1 Signaling. Thyroid 2017; 27(5) doi: 10.1089/thy.2016.0432
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| 34 |
Meixuan Liu, Jingjing Lu, Qian Zhang, Yunxuan Zhang, Zhongliang Guo. Clara cell 16 KDa protein mitigates house dust mite-induced airway inflammation and damage via regulating airway epithelial cell apoptosis in a manner dependent on HMGB1-mediated signaling inhibition. Molecular Medicine 2021; 27(1) doi: 10.1186/s10020-021-00277-4
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| 35 |
Anna Del Prete, Antonella Scalera, Maddalena Diana Iadevaia, Agnese Miranda, Claudio Zulli, Laura Gaeta, Concetta Tuccillo, Alessandro Federico, Carmelina Loguercio. Herbal Products: Benefits, Limits, and Applications in Chronic Liver Disease. Evidence-Based Complementary and Alternative Medicine 2012; 2012 doi: 10.1155/2012/837939
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| 36 |
Tubing Xu, Xiaojun Wang, Geng Chen, Yu He, Ping Bie. Autologous bone marrow stem cell transplantation attenuates hepatocyte apoptosis in a rat model of ex vivo liver resection and liver autotransplantation. Journal of Surgical Research 2013; 184(2) doi: 10.1016/j.jss.2013.03.095
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| 37 |
Chang-lin Zhai, Mei-qi Zhang, Yun Zhang, Hong-xia Xu, Jing-min Wang, Gui-peng An, Yuan-yuan Wang, Li Li. Glycyrrhizin protects rat heart against ischemia-reperfusion injury through blockade of HMGB1-dependent phospho-JNK/Bax pathway. Acta Pharmacologica Sinica 2012; 33(12) doi: 10.1038/aps.2012.112
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| 38 |
Guangyi Zhao, Jianying Zhang, Daibang Nie, Yiqin Zhou, Feng Li, Kentaro Onishi, Timothy Billiar, James H-C. Wang, Yufeng Dong. HMGB1 mediates the development of tendinopathy due to mechanical overloading. PLOS ONE 2019; 14(9) doi: 10.1371/journal.pone.0222369
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| 39 |
Kun Chen, Rong Yang, Fa-Qian Shen, Hai-Liang Zhu. Advances in Pharmacological Activities and Mechanisms of Glycyrrhizic Acid. Current Medicinal Chemistry 2020; 27(36) doi: 10.2174/0929867325666191011115407
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| 40 |
Yijie Zhang, Qi Pan, Yongfeng Liu. CXCL16 silencing alleviates hepatic ischemia reperfusion injury during liver transplantation by inhibiting p38 phosphorylation. Pathology - Research and Practice 2020; 216(5) doi: 10.1016/j.prp.2020.152913
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| 41 |
Xiaowei Huo, Xiangbo Meng, Jun Zhang, Yanyan Zhao. Hepatoprotective effect of different combinations of 18α-and 18β-Glycyrrhizic acid against CCl4-induced liver injury in rats. Biomedicine & Pharmacotherapy 2020; 122 doi: 10.1016/j.biopha.2019.109354
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| 42 |
Cedric Stephan Graebin. Sweeteners. Reference Series in Phytochemistry 2016; doi: 10.1007/978-3-319-26478-3_15-1
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| 43 |
Xuanbin Wang, Longchao Xiang, Hongliang Li, Ping Chen, Yibin Feng, Jingxuan Zhang, Nian Yang, Fei Li, Ye Wang, Quifang Zhang, Fang Li, Fengjun Cao. The Role of HMGB1 Signaling Pathway in the Development and Progression of Hepatocellular Carcinoma: A Review. International Journal of Molecular Sciences 2015; 16(9) doi: 10.3390/ijms160922527
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| 44 |
Zhen Hu, Xiaoyun Wang, Lei Gong, Gaojue Wu, Xiaobin Peng, Xuejun Tang. Role of high-mobility group box 1 protein in inflammatory bowel disease. Inflammation Research 2015; 64(8) doi: 10.1007/s00011-015-0841-x
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