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For: Melo CM, Carvalho KMMB, Neves JCS, Morais TC, Rao VS, Santos FA, Brito GAC, Chaves MH. α,β-amyrin, a natural triterpenoid ameliorates L-arginine-induced acute pancreatitis in rats. World J Gastroenterol 2010; 16(34): 4272-4280 [PMID: 20818810 DOI: 10.3748/wjg.v16.i34.4272]
URL: https://www.wjgnet.com/1007-9327/full/v16/i34/4272.htm
Number Citing Articles
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Meriem El Fessikh, Hamza Elhrech, Amina El Yahyaoui El Idrissi, Learn-Han Lee, Waleed Al Abdulmonem, Nasreddine El Omari, Abdelhakim Bouyahya. Sustainable valorization of olive stone by-products: Opportunities and challengesJournal of Food Composition and Analysis 2025; 142 doi: 10.1016/j.jfca.2025.107495
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Zeynep KOLOREN, Ömer ERTÜRK, Zülal ATLI ŞEKEROĞLU, Ülkü KARAMAN. Amoebicidal and Cytotoxic Activity of Propolis collected from Different Regions in Turkey on Acanthamoeba castellanii TrophozoitesMiddle Black Sea Journal of Health Science 2023; 9(2) doi: 10.19127/mbsjohs.1253511
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Rahmat Allah Fatahian Dehkordi, Iraj Karimi, Behnaz Karimi, Reyhaneh Ghasemi Eshkaftaki, Reza Abtahi, Hanieh Mohammadi. Effect of pancreatin on acute pancreatitis resulting from L-arginine administration in mice, a morpho-histopathological and biochemical studyBrazilian Journal of Pharmaceutical Sciences 2023; 59 doi: 10.1590/s2175-97902023e21494
4
Prabhu Subramani, Senthil Murugappan, Gajalakshmi Ganesh, Sumathi Jones, Devi Mani. Determination of Phytochemical Properties “Amman Pacharisi”–Euphorbia hirta LinnJournal of Pharmacy and Bioallied Sciences 2024; 16(Suppl 5) doi: 10.4103/jpbs.jpbs_822_24
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Shaza H. Aly, Sara Saeed Kotb, Mayada M. Refaat, Youssef I. Nagla, Mina A. Hanna, Shrouk M. Kamel, Mary M. Rizk, Abdelrahman M. Mohamed, Haidy A. Gad. Phytochemical profiling and wound healing properties of essential oil isolated from Rosmarinus officinalis aerial parts: GC/MS analysis and in vitro studiesNew Journal of Chemistry 2026; 50(26) doi: 10.1039/D6NJ01514J
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Shabnam Asfaram, Mahdi Fakhar, Masoud Keighobadi, Javad Akhtari. Promising Anti-Protozoan Activities of Propolis (Bee Glue) as Natural Product: A ReviewActa Parasitologica 2021; 66(1) doi: 10.1007/s11686-020-00254-7
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Munazza Ahmed, Maitha M. Alaryani, Aya Mudhafar Al-Azawi, Shab Alkoujah, Shatha K. Alyammahi, Abdalla El-Kabalawy, Sameh S.M. Soliman. Geophytochemical and ethnopharmacological insights into Calotropis procera : bridging traditional knowledge and modern therapeutics Natural Product Research 2025;  doi: 10.1080/14786419.2025.2552209
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Anna Szakiel, Cezary Pączkowski, Flora Pensec, Christophe Bertsch. Fruit cuticular waxes as a source of biologically active triterpenoidsPhytochemistry Reviews 2012; 11(2-3) doi: 10.1007/s11101-012-9241-9
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Jaenjira Angsusing, Sudarshan Singh, Weerasak Samee, Sarin Tadtong, Leanne Stokes, Maria O’Connell, Hanna Bielecka, Nopparut Toolmal, Supachoke Mangmool, Chuda Chittasupho. Anti-Inflammatory Activities of Yataprasen Thai Traditional Formulary and Its Active Compounds, Beta-Amyrin and Stigmasterol, in RAW264.7 and THP-1 CellsPharmaceuticals 2024; 17(8) doi: 10.3390/ph17081018
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Pooja Sharma, Richa Shri, Fidele Ntie-Kang, Suresh Kumar. Phytochemical and Ethnopharmacological Perspectives of Ehretia laevisMolecules 2021; 26(12) doi: 10.3390/molecules26123489
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Senthilkumar Vellur, Parasuraman Pavadai, Sureshbabu Ram Kumar Pandian, Chandrasekar Palanichamy, Shanmugampillai Jeyarajaguru Kabilan, Krishnan Sundar, Suthendran Kannan, Selvaraj Kunjiappan. Optimization of ultrasound-assisted extraction of bioactive chemicals from Hemidesmus indicus (L.) R.Br. using response surface methodology and adaptive neuro-fuzzy inference systemFood Science and Biotechnology 2024; 33(2) doi: 10.1007/s10068-023-01351-9
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Rownak Jahan, Abdullah Al-Nahain, Snehali Majumder, Mohammed Rahmatullah. Ethnopharmacological Significance of Eclipta alba (L.) Hassk. (Asteraceae)International Scholarly Research Notices 2014; 2014 doi: 10.1155/2014/385969
14
Caroline M. Melo, Talita C. Morais, Adriana R. Tomé, Gerly Anne C. Brito, Mariana H. Chaves, Vietla S. Rao, Flávia A. Santos. Anti-inflammatory effect of α,β-amyrin, a triterpene from Protium heptaphyllum, on cerulein-induced acute pancreatitis in miceInflammation Research 2011; 60(7) doi: 10.1007/s00011-011-0321-x
15
Tao Zhang, Ruijie Liu, Ming Chang, Qingzhe Jin, Hui Zhang, Xingguo Wang. Health benefits of 4,4-dimethyl phytosterols: an exploration beyond 4-desmethyl phytosterolsFood & Function 2020; 11(1) doi: 10.1039/C9FO01205B
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Balázs Kui, Zsolt Balla, Eszter T Végh, Petra Pallagi, Viktória Venglovecz, Béla Iványi, Tamás Takács, Péter Hegyi, Zoltán Rakonczay. Recent advances in the investigation of pancreatic inflammation induced by large doses of basic amino acids in rodentsLaboratory Investigation 2014; 94(2) doi: 10.1038/labinvest.2013.143
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Nwakaego E. Nweze, Henry O. Okoro, Majed Al Robaian, Ruwida M. K. Omar, Terrumun A. Tor-Anyiin, David G. Watson, John O. Igoli. Effects of Nigerian red propolis in rats infected with Trypanosoma brucei bruceiComparative Clinical Pathology 2017; 26(5) doi: 10.1007/s00580-017-2497-0
18
Najeeb Jahan, Sayeedur Rahman. Validation of Unani concept of islah-e-advia by gas chromatography-mass spectroscopy fingerprinting of Mazaryun (Daphne oleoides Schreb.) before and after detoxificationJournal of Research in Unani Medicine 2022; 11(1) doi: 10.4103/JRUM.JRUM_24_23
19
Nahla E. El-Ashmawy, Naglaa F. Khedr, Hoda A. El-Bahrawy, Omnia B. Hamada. Anti-inflammatory and Antioxidant Effects of Captopril Compared to Methylprednisolone in l-Arginine-Induced Acute PancreatitisDigestive Diseases and Sciences 2018; 63(6) doi: 10.1007/s10620-018-5036-1
20
Amaurilio O. Nogueira, Yasmin Ingrid S. Oliveira, Beatriz L. Adjafre, Maria E. Amaral de Moraes, Gislei F. Aragão. Pharmacological effects of the isomeric mixture of alpha and beta amyrin from Protium heptaphyllum: a literature reviewFundamental & Clinical Pharmacology 2019; 33(1) doi: 10.1111/fcp.12402
21
Aaron O. Antwi, David D. Obiri, Newman Osafo, Arnold D. Forkuo, Leslie B. Essel. Stigmasterol inhibits lipopolysaccharide-induced innate immune responses in murine modelsInternational Immunopharmacology 2017; 53 doi: 10.1016/j.intimp.2017.10.018
22
Vahid Reza Askari, Narges Fereydouni, Vafa Baradaran Rahimi, Nafiseh Askari, Amir Hossein Sahebkar, Pouria Rahmanian-Devin, Alireza Samzadeh-Kermani. β-Amyrin, the cannabinoid receptors agonist, abrogates mice brain microglial cells inflammation induced by lipopolysaccharide/interferon-γ and regulates Mφ1/Mφ2 balancesBiomedicine & Pharmacotherapy 2018; 101 doi: 10.1016/j.biopha.2018.02.098
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Divya Rathi, Akanksha Pareek, Saurabh Gayali, Subhra Chakraborty, Niranjan Chakraborty. Variety-specific nutrient acquisition and dehydration-induced proteomic landscape of grasspea ( Lathyrus sativus L.)Journal of Proteomics 2018; 183 doi: 10.1016/j.jprot.2018.05.013
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Danielle Gomes Santana, Alan Santos Oliveira, Marília Trindade de Santana Souza, José Thiago do Carmo Santos, Neuza Mariko Aymoto Hassimotto, Ana Mara de Oliveira e Silva, Renata Grespan, Enilton Aparecido Camargo, Letizia Angiolella. Vaccinium macrocarpon Aiton Extract Ameliorates Inflammation and Hyperalgesia through Oxidative Stress Inhibition in Experimental Acute PancreatitisEvidence-Based Complementary and Alternative Medicine 2018; 2018(1) doi: 10.1155/2018/9646937
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Mentari Putri Pratami, Wawan Sujarwo, Miftahul Huda Fendiyanto, Ratna Yuniati, Ifan Rizky Kurniyanto, Nuniek Widiayani, Mahmoud F. Seleiman, Nawab Ali, Muhammad Fuad Anshori. Metabolite profiling of some organs and the potential of Mukia javanica as an antihypertensionFrontiers in Sustainable Food Systems 2025; 8 doi: 10.3389/fsufs.2024.1487446
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Genlin Zhang, Qian Cao, Jingzhu Liu, Baiyang Liu, Jun Li, Chun Li. Refactoring β‐amyrin synthesis in Saccharomyces cerevisiaeAIChE Journal 2015; 61(10) doi: 10.1002/aic.14950
27
Nahla E. El-Ashmawy, Naglaa F. Khedr, Hoda A. El-Bahrawy, Omnia B. Hamada. Suppression of inducible nitric oxide synthase and tumor necrosis factor-alpha level by lycopene is comparable to methylprednisolone in acute pancreatitisDigestive and Liver Disease 2018; 50(6) doi: 10.1016/j.dld.2018.01.131
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Nenad Naumovski, Senaka Ranadheera, Jackson Thomas, Ekavi Georgousopoulou, Duane Mellor. Utilisation of Bioactive Compounds from Agricultural and Food Waste2017;  doi: 10.1201/9781315151540-2
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Raíssa C. Oliveira, Paulo N. Bandeira, Telma G. Lemos, Hélcio S. dos Santos, Murilo S.S. Julião, Emmanuel S. Marinho, Francisco Flávio da S. Lopes, Selene Maia de Morais, João Pedro da Hora, Ana J. de Morais Bento, Igor K.C. Lima, Carlos E.S. Nogueira, Gilberto D. Saraiva, Antônio C.H. Barreto, Raimundo Braz-Filho, Alexandre M.R. Teixeira. Spectroscopic, physicochemical, and pharmacokinetic analysis of α,β-amyrin mixture obtained from Protium heptaphyllum (Aubl.) Marchand resinJournal of Molecular Structure 2022; 1256 doi: 10.1016/j.molstruc.2022.132551
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Rgia A Othman, Mohammed H Moghadasian. Beyond cholesterol-lowering effects of plant sterols: clinical and experimental evidence of anti-inflammatory propertiesNutrition Reviews 2011; 69(7) doi: 10.1111/j.1753-4887.2011.00399.x
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Patrícia D. O. de Almeida, Ana Paula de A. Boleti, André Luis Rüdiger, Geane A. Lourenço, Valdir Florêncio da Veiga Junior, Emerson S. Lima. Anti-Inflammatory Activity of Triterpenes Isolated fromProtium paniculatumOil-ResinsEvidence-Based Complementary and Alternative Medicine 2015; 2015 doi: 10.1155/2015/293768
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Jiangping Ni, Genlin Zhang, Lei Qin, Jun Li, Chun Li. Simultaneously down-regulation of multiplex branch pathways using CRISPRi and fermentation optimization for enhancing β-amyrin production in Saccharomyces cerevisiaeSynthetic and Systems Biotechnology 2019; 4(2) doi: 10.1016/j.synbio.2019.02.002
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Eun-Ha Kim, Hanyoung Choi, Hyoun-Min Park, Myeong-Ji Kim, Hajeong Kang, Sang-Gu Lee, Hyun Uk Kim, Young-Soo Chung, Seon-Woo Oh. Non-targeted metabolite profiling reveals substantial equivalence of omega-3 enriched PfFAD3-1 transgenic soybeans GM Crops & Food 2026; 17(1) doi: 10.1080/21645698.2026.2620886
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Tran Duc Viet, La Hoang Anh, Tran Dang Xuan, Ngo Duy Dong. The Pharmaceutical Potential of α- and β-AmyrinsNutraceuticals 2025; 5(3) doi: 10.3390/nutraceuticals5030021
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Sana Wahid, Muhammad Ali Versiani, Sajid Jahangir, Khurshid Jawaid, Maryam Shafique, Huma Khan, Shaheen Faizi. Phytochemical and Biological Activities of Pseudocalymma elegans: A False GarlicChemistry & Biodiversity 2017; 14(10) doi: 10.1002/cbdv.201700222
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Sahar Y. Al-Okbi, Ayman A. Mohammad, Dina El-Sayed Helmy Azab, Shaimaa E. Mohammed. Valorization of orange seeds oil as a health-promoting ingredient in functional mayonnaise productionJournal of Food Measurement and Characterization 2026; 20(3) doi: 10.1007/s11694-025-03870-x
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Saikat Haldar, Balaji S. Kale, Dipesh D. Jadhav, Hirekodathakallu V. Thulasiram. Lipase mediated separation of triterpene structural isomers, α- and β-amyrinTetrahedron Letters 2014; 55(19) doi: 10.1016/j.tetlet.2014.04.015
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Tran Duc Viet, Tran Dang Xuan, La Hoang Anh. α-Amyrin and β-Amyrin Isolated from Celastrus hindsii Leaves and Their Antioxidant, Anti-Xanthine Oxidase, and Anti-Tyrosinase PotentialsMolecules 2021; 26(23) doi: 10.3390/molecules26237248
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Muhammad Saad Ahmed, Sana Ikram, Aamir Rasool, Chun Li. Design and construction of short synthetic terminators for β-amyrin production in Saccharomyces cerevisiaeBiochemical Engineering Journal 2019; 146 doi: 10.1016/j.bej.2019.03.011
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A Chicca, J Marazzi, J Gertsch. The antinociceptive triterpene β‐amyrin inhibits 2‐arachidonoylglycerol (2‐AG) hydrolysis without directly targeting cannabinoid receptorsBritish Journal of Pharmacology 2012; 167(8) doi: 10.1111/j.1476-5381.2012.02059.x
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Chia-Cheng Wei, Chun-Han Chang, Vivian Hsiu-Chuan Liao. Anti-Parkinsonian effects of β-amyrin are regulated via LGG-1 involved autophagy pathway in Caenorhabditis elegansPhytomedicine 2017; 36 doi: 10.1016/j.phymed.2017.09.002
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Walaa Yehia Abdelzaher, Sabreen Mahmoud Ahmed, Nermeen N. Welson, Najat Marraiki, Gaber El-Saber Batiha, Maha Yehia Kamel. RETRACTED: Vinpocetine ameliorates L-arginine induced acute pancreatitis via Sirt1/Nrf2/TNF pathway and inhibition of oxidative stress, inflammation, and apoptosisBiomedicine & Pharmacotherapy 2021; 133 doi: 10.1016/j.biopha.2020.110976
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Masaya Nakamura, Jong-Hwan Ra, Ju-Sung Kim. Evaluation of biological activity for Dangyuja (Citrus grandis) leaves and investigation of optimal concentrations extracted by alternative ethanol concentrationsJournal of Plant Biotechnology 2019; 46(1) doi: 10.5010/JPB.2019.46.1.045
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Fernanda Guilhon‐Simplicio, Carlos Klinger Rodrigues Serrão, Ana Cristina da Silva Pinto, Paulo Anastácio Furtado Pacheco, Robson Xavier Faria, David Rodrigues da Rocha, Vitor Francisco Ferreira, Raimundo Carlos Pereira‐Junior, An Matheeussen, Adrienn Baán, Filip Kiekens, Maria de Meneses Pereira, Emerson Silva Lima, Hans De Winter, Paul Cos. Semisynthetic triterpenes led to the generation of selective antitrypanosomal lead compoundsChemical Biology & Drug Design 2022; 99(6) doi: 10.1111/cbdd.14040
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Tamsheel Fatima Roohi, K. L. Krishna, Faiyaz Shakeel. Synergistic modulation of endoplasmic reticulum stress pathway, oxidative DNA damage and apoptosis by β-amyrin and metformin in mitigating hyperglycemia-induced renal damage using adult zebrafish modelBMC Pharmacology and Toxicology 2024; 25(1) doi: 10.1186/s40360-024-00797-9
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Giyeol Han, Dong Gun Lee. Antibacterial Mode of Action of β-Amyrin Promotes Apoptosis-Like Death in Escherichia coli by Producing Reactive Oxygen SpeciesJournal of Microbiology and Biotechnology 2022; 32(12) doi: 10.4014/jmb.2209.09040
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Ranjit K. Harwansh, Rohitas Deshmukh. Recent Insight into UV-induced Oxidative Stress and Role of Herbal Bioactives in the Management of Skin AgingCurrent Pharmaceutical Biotechnology 2024; 25(1) doi: 10.2174/1389201024666230427110815
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Sergio Martínez-Luis, Lilia Chérigo. Bioactive Compounds in Mangroves and their AssociatesReference Series in Phytochemistry 2026;  doi: 10.1007/978-3-031-91066-1_14
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Muhammad Yusuf Abduh, Tri Ramadianti Shafitri, Elfahmi Elfahmi. Chemical profiling, bioactive compounds, antioxidant, and anti-inflammatory activities of Indonesian propolis extract produced by Tetragonula laevicepsHeliyon 2024; 10(19) doi: 10.1016/j.heliyon.2024.e38736
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Nikola M. Stojanović, Milica Stevanović, Pavle Randjelović, Katarina Mitić, Vladmir Petrović, Dušan Sokolović, Bojan Mladenović, Jelena Lalić, Niko S. Radulović. Low dose of carvacrol prevents rat pancreas tissue damage after L-arginine application, while higher doses cause pancreatic tissue impairmentFood and Chemical Toxicology 2019; 128 doi: 10.1016/j.fct.2019.04.010
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Kari-Anne Bjørnkjær-Nielsen, Charlotte Reinhard Bjørnvad. Corticosteroid treatment for acute/acute-on-chronic experimental and naturally occurring pancreatitis in several species: a scoping review to inform possible use in dogsActa Veterinaria Scandinavica 2021; 63(1) doi: 10.1186/s13028-021-00592-0
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Israel Matos, Allisson Freire Bento, Rodrigo Marcon, Rafaela Franco Claudino, João B. Calixto. Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: The relevance of cannabinoid systemMolecular Immunology 2013; 54(3-4) doi: 10.1016/j.molimm.2013.01.018
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Zhanar Iskakova, Akmaral Kozhantayeva, Gaukhar Tazhkenova, Togzhan Mashan, Kuldi Tosmaganbetova, Yerbolat Tashenov. Investigation of Chemical Constituents of Chamaenerion latifolium L.Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2021; 21(3) doi: 10.2174/1871523022666221125111235
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Sergio Martínez-Luis, Lilia Chérigo. Bioactive Compounds in Mangroves and their AssociatesReference Series in Phytochemistry 2025;  doi: 10.1007/978-3-031-63920-3_14-1
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Sahar Y. Al-Okbi, Shaimaa E. Mohammed, Enas S. K. Al-Siedy. Pulmonary and hepatic fluorosis in rats and the potential prevention by nutraceuticals prepared from green and red pepper seedDiscover Food 2025; 5(1) doi: 10.1007/s44187-025-00521-4
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Jaladi Sowjanya, Toorpu Sandhya, Bantal Veeresh. Ameliorating Effect of Eugenol on L-arginine Induced Acute Pancreatitis and Associated Pulmonary Complications in RatsPharmacologia 2012; 3(12) doi: 10.5567/pharmacologia.2012.657.664