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For: Wang AY, Lian LH, Jiang YZ, Wu YL, Nan JX. Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway. World J Gastroenterol 2010; 16(3): 384-391 [PMID: 20082487 DOI: 10.3748/wjg.v16.i3.384]
URL: https://www.wjgnet.com/1007-9327/full/v16/i3/384.htm
Number Citing Articles
1
Cheng-lin Fu, Ying Liu, Jing Leng, Jing Zhang, Yu-fang He, Chen Chen, Zi Wang, Wei Li. Platycodin D protects acetaminophen-induced hepatotoxicity by inhibiting hepatocyte MAPK pathway and apoptosis in C57BL/6J miceBiomedicine & Pharmacotherapy 2018; 107: 867 doi: 10.1016/j.biopha.2018.08.082
2
Karolin Thiel, Wilfried Klingert, Kathrin Klingert, Matthias H Morgalla, Martin U Schuhmann, Pamela Leckie, Yalda Sharifi, Nathan A Davies, Rajiv Jalan, Andreas Peter, Christian Grasshoff, Alfred Königsrainer, Martin Schenk, Christian Thiel. Porcine model characterizing various parameters assessing the outcome after acetaminophen intoxication induced acute liver failureWorld Journal of Gastroenterology 2017; 23(9): 1576-1585 doi: 10.3748/wjg.v23.i9.1576
3
Li-Hua Lian, Yan-Ling Wu, Ying Wan, Xin Li, Wen-Xue Xie, Ji-Xing Nan. Anti-apoptotic activity of gentiopicroside in d-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failureChemico-Biological Interactions 2010; 188(1): 127 doi: 10.1016/j.cbi.2010.06.004
4
Mariel R. B. Betto, Lais F. Lazarotto, Tatiane T. N. Watanabe, David Driemeier, Carlos E. Leite, Maria M. Campos. Effects of treatment with enalapril on hepatotoxicity induced by acetaminophen in miceNaunyn-Schmiedeberg's Archives of Pharmacology 2012; 385(9): 933 doi: 10.1007/s00210-012-0774-7
5
Fu-Chao Liu, Hung-Chen Lee, Chia-Chih Liao, Allen H. Li, Huang-Ping Yu. Tropisetron Protects Against Acetaminophen-Induced Liver Injury via Suppressing Hepatic Oxidative Stress and Modulating the Activation of JNK/ERK MAPK PathwaysBioMed Research International 2016; 2016: 1 doi: 10.1155/2016/1952947
6
GIOU-TENG YIANG, YUNG-LUNG YU, KO-TING LIN, JEN-NI CHEN, WEI-JUNG CHANG, CHYOU-WEI WEI. Acetaminophen induces JNK/p38 signaling and activates the caspase-9-3-dependent cell death pathway in human mesenchymal stem cellsInternational Journal of Molecular Medicine 2015; 36(2): 485 doi: 10.3892/ijmm.2015.2254
7
Shogo Takahashi, Naoki Tanaka, Srujana Golla, Tatsuki Fukami, Kristopher W. Krausz, Marianne A. Polunas, Blair C. Weig, Yusuke Masuo, Cen Xie, Changtao Jiang, Frank J. Gonzalez. Editor’s Highlight: Farnesoid X Receptor Protects Against Low-Dose Carbon Tetrachloride-Induced Liver Injury Through the Taurocholate-JNK PathwayToxicological Sciences 2017; 158(2): 334 doi: 10.1093/toxsci/kfx094
8
Hyunseong Kim, Dong June Keum, Jung won Kwak, Hwan-Suck Chung, Hyunsu Bae, Bruno Lomonte. Bee Venom Phospholipase A2 Protects against Acetaminophen-Induced Acute Liver Injury by Modulating Regulatory T Cells and IL-10 in MicePLoS ONE 2014; 9(12): e114726 doi: 10.1371/journal.pone.0114726
9
Longyue Zhou, Shankang Chen, Yuanyi Wei, Yihui Sun, Yifan Yang, Bingqi Lin, Yuhao Li, Chunxia Wang. Glycyrrhizic acid restores the downregulated hepatic ACE2 signaling in the attenuation of mouse steatohepatitisEuropean Journal of Pharmacology 2024; 967: 176365 doi: 10.1016/j.ejphar.2024.176365
10
Chien-Ta Wu, Jeng-Shyan Deng, Wen-Chin Huang, Po-Chou Shieh, Mei-Ing Chung, Guan-Jhong Huang. Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 SignalingOxidative Medicine and Cellular Longevity 2019; 2019: 1 doi: 10.1155/2019/9056845
11
Ka-Lok Wong, PaulPui-Hay But, Pang-Chui Shaw. Evaluation of seven DNA barcodes for differentiating closely related medicinal Gentiana species and their adulterantsChinese Medicine 2013; 8(1) doi: 10.1186/1749-8546-8-16
12
Kun-Chang Wu, Yu-Ling Ho, Yueh-Hsiung Kuo, Shyh-Shyun Huang, Guan-Jhong Huang, Yuan-Shiun Chang. Hepatoprotective Effect of Ugonin M, A Helminthostachys zeylanica Constituent, on Acetaminophen-Induced Acute Liver Injury in MiceMolecules 2018; 23(10): 2420 doi: 10.3390/molecules23102420
13
Nacera Baali, Zahia Belloum, Samiya Baali, Beatrice Chabi, Laurence Pessemesse, Gilles Fouret, Souad Ameddah, Fadila Benayache, Samir Benayache, Christine Feillet-Coudray, Gérard Cabello, Chantal Wrutniak-Cabello. Protective Activity of Total Polyphenols from Genista quadriflora Munby and Teucrium polium geyrii Maire in Acetaminophen-Induced Hepatotoxicity in RatsNutrients 2016; 8(4): 193 doi: 10.3390/nu8040193
14
Yu Pan, Yan‐Li Zhao, Ji Zhang, Wan‐Yi Li, Yuan‐Zhong Wang. Phytochemistry and Pharmacological Activities of the Genus Gentiana (Gentianaceae)Chemistry & Biodiversity 2016; 13(2): 107 doi: 10.1002/cbdv.201500333
15
Xiaowen Tang, Qiaoling Yang, Fan Yang, Junting Gong, Han Han, Li Yang, Zhengtao Wang. Target profiling analyses of bile acids in the evaluation of hepatoprotective effect of gentiopicroside on ANIT-induced cholestatic liver injury in miceJournal of Ethnopharmacology 2016; 194: 63 doi: 10.1016/j.jep.2016.08.049
16
Xiuhong Wu, Shuhan Tang, Yan Jin, Shanshan Wang, Xijun Wang, Masao Hattori, Hailong Zhang, Zhigang Wang. Determination of the metabolic profile of gentianine after oral administration to rats by high performance liquid chromatography/electrospray ionization-trap mass spectrometryJournal of Chromatography B 2015; 989: 98 doi: 10.1016/j.jchromb.2015.01.007
17
C. Delgado-Montemayor, P. Cordero-Pérez, R. Salazar-Aranda, N. Waksman-Minsky. Models of hepatoprotective activity assessmentMedicina Universitaria 2015; 17(69): 222 doi: 10.1016/j.rmu.2015.10.002
18
Li-Hua Lian, Xuejun Jin, Yan-Ling Wu, Xing Fu Cai, Jung Joon Lee, Ji-Xing Nan. Hepatoprotective Effects of Sedum sarmentosum on D-Galactosamine/Lipopolysaccharide–Induced Murine Fulminant Hepatic FailureJournal of Pharmacological Sciences 2010; 114(2): 147 doi: 10.1254/jphs.10045FP
19
Gaole Zhang, Yun Li, Wenlong Wei, Jiayuan Li, Haoju Li, Yong Huang, De-an Guo. Metabolomics Combined with Multivariate Statistical Analysis for Screening of Chemical Markers between Gentiana scabra and Gentiana rigescensMolecules 2020; 25(5): 1228 doi: 10.3390/molecules25051228
20
The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and d-galactosamine in miceJournal of Ethnopharmacology 2010; 132(2): 450 doi: 10.1016/j.jep.2010.08.025
21
Hartmut Jaeschke, Luqi Duan, Jephte Y. Akakpo, Anwar Farhood, Anup Ramachandran. The role of apoptosis in acetaminophen hepatotoxicityFood and Chemical Toxicology 2018; 118: 709 doi: 10.1016/j.fct.2018.06.025
22
Tsai‑Kun Wu, Hsiao‑Chun Liu, Shu‑Yu Lin, Yung‑Luen Yu, Chyou‑Wei Wei. Extracts from guava fruit protect renal tubular endothelial cells against acetaminophen‑induced cytotoxicityMolecular Medicine Reports 2018;  doi: 10.3892/mmr.2018.8529
23
Mylanayakanahosahalli Chandrashekar Indumathi, Kamatam Swetha, Kandahalli Venkataranganayaka Abhilasha, Shiva Siddappa, Shivamadhaiah Manjula Kumar, Govinda Keerthi Prasad, Chu-Huang Chen, Gopal Kedihithlu Marathe. Selenium Ameliorates Acetaminophen-Induced Oxidative Stress via MAPK and Nrf2 Pathways in MiceBiological Trace Element Research 2024; 202(6): 2598 doi: 10.1007/s12011-023-03845-3
24
Jianping Jiang, Li Yan, Zheng Shi, Lixia Wang, Letian Shan, Thomas Efferth. Hepatoprotective and anti-inflammatory effects of total flavonoids of Qu Zhi Ke (peel of Citrus changshan-huyou) on non-alcoholic fatty liver disease in rats via modulation of NF-κB and MAPKsPhytomedicine 2019; 64: 153082 doi: 10.1016/j.phymed.2019.153082
25
Vivek Chowdhary, Kun-yu Teng, Sharda Thakral, Bo Zhang, Cho-hao Lin, Nissar Wani, Lei Bruschweiler-Li, Xiaoli Zhang, Laura James, Dakai Yang, Norman Junge, Rafael Brüschweiler, William M. Lee, Kalpana Ghoshal. miRNA-122 Protects Mice and Human Hepatocytes from Acetaminophen Toxicity by Regulating Cytochrome P450 Family 1 Subfamily A Member 2 and Family 2 Subfamily E Member 1 ExpressionThe American Journal of Pathology 2017; 187(12): 2758 doi: 10.1016/j.ajpath.2017.08.026
26
Halil Yaman, Salim Isbilir, Erdinc Cakir, Bulent Uysal. Current issues with paracetamol induced toxicityJournal of Experimental and Integrative Medicine 2011; 1(3): 165 doi: 10.5455/jeim.010711.ed.005
27
Engin Sümer, Gözde Erkanli Senturk, Özlem Unay Demirel, Erdem Yesilada. Comparative biochemical and histopathological evaluations proved that receptacle is the most effective part of Cynara scolymus against liver and kidney damagesJournal of Ethnopharmacology 2020; 249: 112458 doi: 10.1016/j.jep.2019.112458
28
Wei-shun Tian, Jing Zhao, Myung-Kon Kim, Hyun-Jin Tae, In-Shik Kim, Dongchoon Ahn, Hong Pil Hwang, Ming-xian Mao, Byung-Yong Park. Veronica persica ameliorates acetaminophen-induced murine hepatotoxicity via attenuating oxidative stress and inflammationBiomedicine & Pharmacotherapy 2023; 169: 115898 doi: 10.1016/j.biopha.2023.115898
29
James Michael Brown, John G. Ball, Michael Scott Wright, Stephanie Van Meter, Monica A. Valentovic. Novel protective mechanisms for S-adenosyl-l-methionine against acetaminophen hepatotoxicity: Improvement of key antioxidant enzymatic functionToxicology Letters 2012; 212(3): 320 doi: 10.1016/j.toxlet.2012.05.018
30
Yu Liang, Xiangxiao Meng, Zejing Mu, Jun Qian, Baozhong Duan, Li Xu. The complete chloroplast genome and phylogenetic analysis of Gentiana manshurica Kitag from ChinaMitochondrial DNA Part B 2020; 5(2): 1625 doi: 10.1080/23802359.2020.1745107
31
Ali Navid, David M Ng, Benjamin J Stewart, Sergio E Wong, Felice C Lightstone. Quantitative In Silico analysis of transient metabolism of acetaminophen and associated causes of hepatotoxicity in humansIn Silico Pharmacology 2013; 1(1) doi: 10.1186/2193-9616-1-14
32
Li-Hua Lian, Ji-Xing Nan. Hepatoprotective traditional herbs with anti-apoptotic activity may reverse liver fibrosisChemico-Biological Interactions 2011; 190(2-3): 192 doi: 10.1016/j.cbi.2010.10.012
33
İlker Öngüç Aycan, Adnan Tüfek, Orhan Tokgöz, Osman Evliyaoğlu, Uğur Fırat, Gönül Ölmez Kavak, Hüseyin Turgut, Mustafa Uğur Yüksel. Thymoquinone treatment against acetaminophen-induced hepatotoxicity in ratsInternational Journal of Surgery 2014; 12(3): 213 doi: 10.1016/j.ijsu.2013.12.013
34
Han Han, Ai-Zhen Xiong, Chun-Yong He, Qing Liu, Li Yang, Zheng-Tao Wang. Combination of UHPLC/Q-TOF-MS, NMR spectroscopy, and ECD calculation for screening and identification of reactive metabolites of gentiopicroside in humansAnalytical and Bioanalytical Chemistry 2014; 406(6): 1781 doi: 10.1007/s00216-013-7572-z
35
Zhigang Wang, Shuhan Tang, Yan Jin, Yan Zhang, Masao Hattori, Hailong Zhang, Ning Zhang. Two main metabolites of gentiopicroside detected in rat plasma by LC–TOF-MS following 2,4-dinitrophenylhydrazine derivatizationJournal of Pharmaceutical and Biomedical Analysis 2015; 107: 1 doi: 10.1016/j.jpba.2014.12.003
36
Baixin Kou, Yuxin Jiang, Yanan Chen, Jingrong Yang, Jin Sun, Yan Yan, Lili Weng, Chunping Xiao. A Study of Gentianae Radix et Rhizoma Class Differences Based on Chemical Composition and Core EfficacyMolecules 2023; 28(20): 7132 doi: 10.3390/molecules28207132
37
Hung-Chen Lee, Chia-Chih Liao, Yuan-Ji Day, Jiin-Tarng Liou, Allen H. Li, Fu-Chao Liu. IL-17 deficiency attenuates acetaminophen-induced hepatotoxicity in miceToxicology Letters 2018; 292: 20 doi: 10.1016/j.toxlet.2018.04.021
38
Shu Li, Qinglan Wang, Yanyan Tao, Chenghai Liu. Swertiamarin Attenuates Experimental Rat Hepatic Fibrosis by Suppressing Angiotensin II–Angiotensin Type 1 Receptor–Extracellular Signal-Regulated Kinase SignalingJournal of Pharmacology and Experimental Therapeutics 2016; 359(2): 247 doi: 10.1124/jpet.116.234179
39
Wenyan Xie, Chen Chen, Zhihui Jiang, Jian Wang, Matthias F. Melzig, Xiaoying Zhang. Apocynum venetum Attenuates Acetaminophen-Induced Liver Injury in MiceThe American Journal of Chinese Medicine 2015; 43(03): 457 doi: 10.1142/S0192415X15500299
40
Chia-Chih Liao, Huang-Ping Yu, An-Hsun Chou, Hung-Chen Lee, Li-Min Hu, Fu-Chao Liu. Gastrodin Alleviates Acetaminophen-Induced Liver Injury in a Mouse Model Through Inhibiting MAPK and Enhancing Nrf2 PathwaysInflammation 2022; 45(4): 1450 doi: 10.1007/s10753-021-01557-1
41
Yan-Ming Wang, Min Xu, Dong Wang, Hong-Tao Zhu, Chong-Ren Yang, Ying-Jun Zhang. Review on “Long-Dan”, one of the traditional Chinese medicinal herbs recorded in Chinese pharmacopoeiaNatural Products and Bioprospecting 2012; 2(1): 1 doi: 10.1007/s13659-011-0043-3
42
Li-Hua Lian, Yan-Ling Wu, Shun-Zong Song, Ying Wan, Wen-Xue Xie, Xin Li, Ting Bai, Bing-Qing Ouyang, Ji-Xing Nan. Gentiana manshurica Kitagawa Reverses Acute Alcohol-Induced Liver Steatosis through Blocking Sterol Regulatory Element-Binding Protein-1 MaturationJournal of Agricultural and Food Chemistry 2010; 58(24): 13013 doi: 10.1021/jf103976y
43
Alaaeldin Ahmed Hamza, Mona Gamel, Ali Abdalla, Youssef Abdalla, Amr Amin. Gentiana lutea attenuates hepatotoxicity induced by ketoconazole in rats by fortifying the cellular antioxidant defense systemThe Journal of Basic and Applied Zoology 2023; 84(1) doi: 10.1186/s41936-022-00321-7
44
Awais Wahab, Jian-Xin Chen, Cai-Xia Jia, Ghulam Murtaza, Chuan-Hong Wu, Na Wang. Molecular Docking-Based Research on the Potential Anti-Encephalopathy Effect of GentianineWorld Journal of Traditional Chinese Medicine 2021; 7(3): 377 doi: 10.4103/wjtcm.wjtcm_3_21
45
Vladimir Mihailović, Jelena Katanić, Danijela Mišić, Vesna Stanković, Mirjana Mihailović, Aleksandra Uskoković, Jelena Arambašić, Slavica Solujić, Milan Mladenović, Nevena Stanković. Hepatoprotective effects of secoiridoid-rich extracts from Gentiana cruciata L. against carbon tetrachloride induced liver damage in ratsFood Funct. 2014; 5(8): 1795 doi: 10.1039/C4FO00088A
46
Hong-Xu Yang, Yue Shang, Quan Jin, Yan-Ling Wu, Jian Liu, Chun-Ying Qiao, Zi-Ying Zhan, Huan Ye, Ji-Xing Nan, Li-Hua Lian. Gentiopicroside Ameliorates the Progression from Hepatic Steatosis to Fibrosis Induced by Chronic Alcohol IntakeBiomolecules & Therapeutics 2020; 28(4): 320 doi: 10.4062/biomolther.2020.008
47
Hartmut Jaeschke, Mitchell R. McGill, C. David Williams, Anup Ramachandran. Current issues with acetaminophen hepatotoxicity—A clinically relevant model to test the efficacy of natural productsLife Sciences 2011; 88(17-18): 737 doi: 10.1016/j.lfs.2011.01.025
48
Nahid Azarmehr, Parisa Afshar, Mona Moradi, Heibatollah Sadeghi, Hossein Sadeghi, Behnam Alipoor, Bahman Khalvati, Zahra Barmoudeh, Kazem Abbaszadeh-Goudarzi, Amir Hossein Doustimotlagh. Hepatoprotective and antioxidant activity of watercress extract on acetaminophen-induced hepatotoxicity in ratsHeliyon 2019; 5(7): e02072 doi: 10.1016/j.heliyon.2019.e02072
49
Kuo Du, Anup Ramachandran, Hartmut Jaeschke. Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potentialRedox Biology 2016; 10: 148 doi: 10.1016/j.redox.2016.10.001
50
Kuan-Hung Lu, Chun-Ting Liu, Rajasekaran Raghu, Lee-Yan Sheen. Therapeutic Potential of Chinese Herbal Medicines in Alcoholic Liver DiseaseJournal of Traditional and Complementary Medicine 2012; 2(2): 115 doi: 10.1016/S2225-4110(16)30084-0
51
Ngoc Uy Nguyen, Brendan David Stamper. Polyphenols reported to shift APAP-induced changes in MAPK signaling and toxicity outcomesChemico-Biological Interactions 2017; 277: 129 doi: 10.1016/j.cbi.2017.09.007
52
Vladimir Mihailović, Mirjana Mihailović, Aleksandra Uskoković, Jelena Arambašić, Danijela Mišić, Vesna Stanković, Jelena Katanić, Milan Mladenović, Slavica Solujić, Sanja Matić. Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in ratsFood and Chemical Toxicology 2013; 52: 83 doi: 10.1016/j.fct.2012.10.034
53
Min Jiang, Ben-Wen Cui, Yan-Ling Wu, Ji-Xing Nan, Li-Hua Lian. Genus Gentiana: A review on phytochemistry, pharmacology and molecular mechanismJournal of Ethnopharmacology 2021; 264: 113391 doi: 10.1016/j.jep.2020.113391
54
An-Hsun Chou, Hung-Chen Lee, Chia-Chih Liao, Huang-Ping Yu, Fu-Chao Liu. ERK/NF-kB/COX-2 Signaling Pathway Plays a Key Role in Curcumin Protection against Acetaminophen-Induced Liver InjuryLife 2023; 13(11): 2150 doi: 10.3390/life13112150
55
Chia-Chih Liao, Yuan-Ji Day, Hung-Chen Lee, Jiin-Tarng Liou, An-Hsun Chou, Fu-Chao Liu. ERK Signaling Pathway Plays a Key Role in Baicalin Protection Against Acetaminophen-Induced Liver InjuryThe American Journal of Chinese Medicine 2017; 45(01): 105 doi: 10.1142/S0192415X17500082
56
Fu-Chao Liu, Huang-Ping Yu, Hung-Chen Lee, Chun-Yu Chen, Chia-Chih Liao. The Modulation of Phospho-Extracellular Signal-Regulated Kinase and Phospho-Protein Kinase B Signaling Pathways plus Activity of Macrophage-Stimulating Protein Contribute to the Protective Effect of Stachydrine on Acetaminophen-Induced Liver InjuryInternational Journal of Molecular Sciences 2024; 25(3): 1484 doi: 10.3390/ijms25031484
57
Akintunde Jacob Kehinde. Functional Oil from Black Seed Differentially Inhibits Aldose-reductase and Ectonucleotidase Activities by Up-regulating Cellular Energy in Haloperidol-induced Hepatic Toxicity in Rat LiverJournal of Oleo Science 2017; 66(9): 1051 doi: 10.5650/jos.ess17036