| For: | Wu TY, Ding SQ, Liu JL, Jia JH, Dai RC, Zhu DC, Liang BZ, Qi DT, Sun YF. High-altitude gastrointestinal bleeding: An observation in Qinghai-Tibetan railroad construction workers on Mountain Tanggula. World J Gastroenterol 2007; 13(5): 774-780 [PMID: 17278202 DOI: 10.3748/wjg.v13.i5.774] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v13/i5/774.htm |
| Number | Citing Articles |
| 1 |
John W. Severinghaus. Sightings. High Altitude Medicine & Biology 2007; 8(2) doi: 10.1089/ham.2007.8203
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| 2 |
Jyotsana Bakshi, K.P. Mishra. Identification of biomarkers for gastrointestinal barrier injury and protective role of sodium butyrate in hypobaric hypoxia exposed rats. International Immunopharmacology 2025; 165 doi: 10.1016/j.intimp.2025.115424
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| 3 |
Yihui Chen, Xiaoqi Tang, Xiong Zeng, Ben Han, Huichao Xie, Wei Wang, Lihua Sun, Mingdong Hu, Yuqi Gao, Weidong Xiao. Gastrointestinal syndrome encountered during a train voyage to high altitudes: A 14-day survey of 69 passengers in China. Travel Medicine and Infectious Disease 2024; 59 doi: 10.1016/j.tmaid.2024.102718
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| 4 |
Kelly Mieske, Gerard Flaherty, Timothy O'Brien. Journeys to High Altitude—Risks and Recommendations for Travelers with Preexisting Medical Conditions. Journal of Travel Medicine 2010; 17(1) doi: 10.1111/j.1708-8305.2009.00369.x
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| 5 |
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| 6 |
Mingke Jiao, Hong Yin, Jie Hu, Wenjuan Xu, Xiao Zhang, Peng Zhang. Effects of Low-Frequency Pulsed Electromagnetic Fields on High-Altitude Stress Ulcer Healing in Rats. BioMed Research International 2019; 2019 doi: 10.1155/2019/6354054
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| 7 |
Manisha Kumari, Chhavi Rai, Anu Kumari, Rajeev Varshney, Ramesh C. Meena. Adaptation under Stressful Environments through Biological Adjustments and Interventions. 2023; doi: 10.1007/978-981-99-7652-2_8
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| 8 |
Elan Small, Brian Strickland, Lake Crawford, Ryan Paterson. Review of Preexisting Medical Conditions in Persons Traveling to High Altitude, 2025. Wilderness & Environmental Medicine 2026; 37(2) doi: 10.1177/10806032251395019
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| 9 |
Ken Zafren, Joanne Feldman, Robert J. Becker, Sarah R. Williams, Eric A. Weiss, Tom Deloughery. D-Dimer Is Not Elevated in Asymptomatic High Altitude Climbers after Descent to 5340 m: The Mount Everest Deep Venous Thrombosis Study (Ev-DVT). High Altitude Medicine & Biology 2011; 12(3) doi: 10.1089/ham.2010.1101
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| 10 |
Latika Mohan, Surinderpal P. Singh, Jayanti Pant. Pilgrim health. Journal of Medical Evidence 2022; 3(1) doi: 10.4103/JME.JME_71_21
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| 11 |
Jin Zeng, Xinxin Yin, Yidan Pang, Jinglei Zhang, Changpeng Xie, Siai Chen, Liping Zhang, Xuejing Li, YuanMing Pan, Juan An. Muscone Ameliorates High-Altitude Hypoxia Gastrointestinal Stress via Modulation of Lactobacillus Murinus and Mitochondrial Metabolism. Journal of Inflammation Research 2025; doi: 10.2147/JIR.S521991
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| 12 |
Andrew M. Luks, Erik R. Swenson. Medication and Dosage Considerations in the Prophylaxis and Treatment of High-Altitude Illness. Chest 2008; 133(3) doi: 10.1378/chest.07-1417
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| 13 |
M. B. Anusha, Naveen Shivanna, G. Phani Kumar, K. R. Anilakumar. Efficiency of selected food ingredients on protein efficiency ratio, glycemic index and in vitro digestive properties. Journal of Food Science and Technology 2018; 55(5) doi: 10.1007/s13197-018-3109-y
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| 14 |
Zachary J. McKenna, Felipe Gorini Pereira, Trevor L. Gillum, Fabiano T. Amorim, Michael R. Deyhle, Christine M. Mermier. High-altitude exposures and intestinal barrier dysfunction. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2022; 322(3) doi: 10.1152/ajpregu.00270.2021
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| 15 |
Huichao Xie, Xiong Zeng, Wensheng Wang, Wei Wang, Ben Han, QianShan Tan, Qiu Hu, Xingyu Liu, Shuaishuai Chen, Jun Chen, Lihua Sun, Yihui Chen, Weidong Xiao. Enteric glial cells aggravate the intestinal epithelial barrier damage by secreting S100β under high-altitude conditions. Molecular Biomedicine 2023; 4(1) doi: 10.1186/s43556-023-00143-1
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| 16 |
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| 17 |
Uday Yanamandra, Celine Raphael, Roopika Peela, Vivek Aggarwal, Velu Nair. Decoding thrombosis at high altitude: A comprehensive scoping review. Medical Journal Armed Forces India 2026; doi: 10.1016/j.mjafi.2026.04.008
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| 18 |
ZACHARY J. MCKENNA, JEREMY B. DUCHARME, QUINT N. BERKEMEIER, JONATHAN W. SPECHT, ZACHARY J. FENNEL, TREVOR L. GILLUM, MICHAEL R. DEYHLE, FABIANO T. AMORIM, CHRISTINE M. MERMIER. Ibuprofen Increases Markers of Intestinal Barrier Injury But Suppresses Inflammation at Rest and After Exercise in Hypoxia. Medicine & Science in Sports & Exercise 2023; 55(1) doi: 10.1249/MSS.0000000000003032
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| 19 |
Peter Bärtsch, Erik R. Swenson. Acute High-Altitude Illnesses. New England Journal of Medicine 2013; 368(24) doi: 10.1056/NEJMcp1214870
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| 20 |
Diego Moretti, Reyna Liria-Domínguez, Gabriela Burgos, Pornpimol Scheuchzer, Nora Barloggio, Christophe Zeder, Nicole U. Stoffel, Michael B. Zimmermann. High-altitude residence increases dietary iron absorption in young women: a prospective stable isotope study in Peru. Blood Red Cells & Iron 2026; 2(2) doi: 10.1016/j.brci.2026.100056
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| 21 |
Jenny Lundeberg, John R. Feiner, Andrew Schober, Jeffrey W. Sall, Helge Eilers, Philip E. Bickler. Increased Cytokines at High Altitude: Lack of Effect of Ibuprofen on Acute Mountain Sickness, Physiological Variables, or Cytokine Levels. High Altitude Medicine & Biology 2018; 19(3) doi: 10.1089/ham.2017.0144
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| 22 |
Cong Song, Yushu Ren, Yanfeng Liu, Ruixuan Cao, Guannan Duan. Oxygen comfort evaluation method based on symptom index for short-term internal migrants to Tibet. Science of The Total Environment 2023; 902 doi: 10.1016/j.scitotenv.2023.166418
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| 23 |
Alison Matthews, Steven G. Schauer, Andrew D. Fisher. Fresh Low Titer O Whole Blood Transfusion in the Austere Medical Environment. Wilderness & Environmental Medicine 2019; 30(4) doi: 10.1016/j.wem.2019.08.006
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| 24 |
Papan K. Hor, Kuntal Ghosh, Suman K. Halder, Jyoti P. Soren, Debabrata Goswami, Debabrata Bera, Som Nath Singh, Sanjai K. Dwivedi, Saswati Parua (Mondal), Maidul Hossain, Keshab C. Mondal. Evaluation of nutrient profile, biochemical composition and anti-gastric ulcer potentialities of khambir, a leavened flat bread. Food Chemistry 2021; 345 doi: 10.1016/j.foodchem.2020.128824
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| 25 |
Xingguang Zhang, Wei Xu, Weilong Zhong, Wencheng Zhang, Cheng Yang, Lisa Duan, Haiyan Niu, Yanmei Dong, Taotao Liu, Shihai Xia, Bangmao Wang. Exploring the links between gut microbiome changes and irritable bowel syndrome in Han populations in the Tibetan Plateau. Journal of Zhejiang University-SCIENCE B 2023; 24(9) doi: 10.1631/jzus.B2200509
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| 26 |
Dante M. Quiñones-Laveriano, Jhony A. De La Cruz-Vargas, Sarah Quintana-Gomez, Virgilio E. Failoc-Rojas, José Lozano-Gutiérrez, Christian R. Mejia. Association between the altitude of residential areas and clinical diagnosis of chronic gastritis in ambulatory patients of Peru: A cross-sectional analytic study. Medwave 2020; 20(06) doi: 10.5867/medwave.2020.06.7972
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| 27 |
Buddha Basnyat. High Altitude Pilgrimage Medicine. High Altitude Medicine & Biology 2014; 15(4) doi: 10.1089/ham.2014.1088
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| 28 |
Prithwis Bhattacharyya, Debasis Pradhan, Prakash Deb. High Altitude Medicine. 2023; doi: 10.1007/978-3-031-35092-4_9
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| 29 |
Ying Han, Liping Ding, Xiang Cheng, Ming Zhao, Tong Zhao, Liang Guo, Xinyang Li, Yanan Geng, Ming Fan, Hong Liao, Lingling Zhu. Hypoxia Augments Cerebral Inflammation in a Dextran Sulfate Sodium-Induced Colitis Mouse Model. Frontiers in Cellular Neuroscience 2020; 14 doi: 10.3389/fncel.2020.611764
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| 30 |
Kunjan Khanna, Malleswara Rao Eslavath, Lilly Ganju, K. P. Mishra, Shashi Bala Singh, Bhuvnesh Kumar. Metagenomic insights into taxonomic and functional shifts under chronic exposure to hypobaric hypoxia induced microbial communities. Journal of Proteins and Proteomics 2021; 12(2) doi: 10.1007/s42485-021-00062-1
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| 31 |
Tian-Yi Wu, Shou Quan Ding, Jin Liang Liu, Man Tang Yu, Jian Hou Jia, Zuo Chuan Chai, Rui Chen Dai, Sheng Lin Zhang, Bao Yu Li, Lei Pan, Bao Zhu Liang, Ji Zhui Zhao, De Tang Qi, Yong Fu Sun, Bengt Kayser. Who Should Not Go High: Chronic Disease and Work at Altitude During Construction of the Qinghai-Tibet Railroad. High Altitude Medicine & Biology 2007; 8(2) doi: 10.1089/ham.2007.1015
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| 32 |
Zhenmei Song, Wenli Li, Jie Zeng, Xuexin Wang, Dezhi Wang, Xingchen Liao, Sayed Haidar as Raza. Lipid droplet associated protein HILPDA promotes hypoxia-induced ferroptosis by driving LPCAT3-mediated polyunsaturated phospholipids enrichment. PLOS One 2026; 21(6) doi: 10.1371/journal.pone.0350129
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| 33 |
Kamla Prasad Mishra, Jyotsana Bakshi, Rajeev Varshney. Adaptation under Stressful Environments through Biological Adjustments and Interventions. 2023; doi: 10.1007/978-981-99-7652-2_7
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| 34 |
Max Gassmann, Martina U. Muckenthaler. Adaptation of iron requirement to hypoxic conditions at high altitude. Journal of Applied Physiology 2015; 119(12) doi: 10.1152/japplphysiol.00248.2015
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| 35 |
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| 36 |
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| 37 |
Mohammed Gamah, Murad Alahdal, Yu Zhang, Yiling Zhou, Qiaorong Ji, Zhouyang Yuan, Ying Han, Xiangqun Shen, Yanming Ren, Wei Zhang. High-altitude hypoxia exacerbates dextran sulfate sodium (DSS)-induced colitis by upregulating Th1 and Th17 lymphocytes. Bioengineered 2021; 12(1) doi: 10.1080/21655979.2021.1975017
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| 38 |
Heiko Fruehauf, Stephan R. Vavricka, Thomas A. Lutz, Max Gassmann, Kacper A. Wojtal, Annina Erb, Marco Maggiorini, Werner Schwizer, Michael Fried, Mark Fox, Oliver Goetze, Thomas Greuter. Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude. Clinical Gastroenterology and Hepatology 2020; 18(10) doi: 10.1016/j.cgh.2019.11.036
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| 39 |
Johannes Mair, Beatrix Schobersberger, Marika Falla, Katharina Hüfner, Rainald Fischer. Mountain and High-Altitude Medicine. 2026; doi: 10.1007/978-3-662-73022-5_21
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| 40 |
YAPING WANG, XIAOHONG XUE, ZHEN ZHAO, XIAOLIN LI, ZHIYONG ZHU. Hypoxia induced apoptosis of rat gastric mucosal cells by activating autophagy through HIF-1α/TERT/mTORC1 pathway. BIOCELL 2022; 46(7) doi: 10.32604/biocell.2022.018559
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| 41 |
Kunjan Khanna, Kamla Prasad Mishra, Sudipta Chanda, Malleswara Rao Eslavath, Lilly Ganju, Bhuvnesh Kumar, Shashi Bala Singh. Effects of Acute Exposure to Hypobaric Hypoxia on Mucosal Barrier Injury and the Gastrointestinal Immune Axis in Rats. High Altitude Medicine & Biology 2019; 20(1) doi: 10.1089/ham.2018.0031
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| 42 |
Shulei Zhao, Sixun Wen, Yallin Guo, Bing Sun, Wengan Chen, Shuaishuai Wang, Guo Yabin, Chun Guo. Impact of altitude on worker health and project efficiency in tunnel construction. International Journal of Industrial Ergonomics 2025; 105 doi: 10.1016/j.ergon.2024.103694
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| 43 |
Priyanka Mishra, Divya Singh, Lilly Ganju, Bhuvnesh Kumar. MicroRNA in gastrointestinal cell signalling. Inflammopharmacology 2018; 26(1) doi: 10.1007/s10787-017-0414-4
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| 44 |
Bowen Wang, Mengjia Peng, Guoyong Kou, Fei Fang, Jinhang Gao. Systemic inflammatory response syndrome and multiple organ dysfunction syndrome caused by acute mountain sickness: a case report and literature review. Frontiers in Physiology 2025; 16 doi: 10.3389/fphys.2025.1546307
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| 45 |
Colin J. Crooks, Joseph Sung, Timothy R. Card. GI Epidemiology. 2014; doi: 10.1002/9781118727072.ch16
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| 46 |
Enrico Donegani, Peter Paal, Thomas Küpper, Urs Hefti, Buddha Basnyat, Anna Carceller, Pierre Bouzat, Rianne van der Spek, David Hillebrandt. Drug Use and Misuse in the Mountains: A UIAA MedCom Consensus Guide for Medical Professionals. High Altitude Medicine & Biology 2016; 17(3) doi: 10.1089/ham.2016.0080
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| 47 |
Zachary J. McKenna, Bryanne N. Bellovary, Jeremy B. Ducharme, Michael R. Deyhle, Andrew D. Wells, Zachary J. Fennel, Jonathan W. Specht, Jonathan M. Houck, Trevor J. Mayschak, Christine M. Mermier. Circulating markers of intestinal barrier injury and inflammation following exertion in hypobaric hypoxia. European Journal of Sport Science 2023; 23(10) doi: 10.1080/17461391.2023.2203107
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| 48 |
K. P. Mishra, Jyotsana Bakshi. Physiological benefits of Akkermansia muciniphila under high-altitude hypoxia. Applied Microbiology and Biotechnology 2023; 107(1) doi: 10.1007/s00253-022-12305-2
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| 49 |
Qian-qian Peng, Zhuoma Basang, Chao-ying Cui, Lei Li, Ji Qian, Quzhen Gesang, La Yang, Zong La, Yang De, Puchi Dawa, Ni Qu, Qu Suo, Zhen Dan, Duoji Xiao, Xiao-feng Wang, Li Jin, Christos A. Ouzounis. Physiological Responses and Evaluation of Effects of BMI, Smoking and Drinking in High Altitude Acclimatization: A Cohort Study in Chinese Han Young Males. PLoS ONE 2013; 8(11) doi: 10.1371/journal.pone.0079346
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| 50 |
Johannes Mair, Beatrix Schobersberger, Marika Falla, Katharina Hüfner, Rainald Fischer. Alpin- und Höhenmedizin. 2025; doi: 10.1007/978-3-662-69578-4_21
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| 51 |
Ailifeire Tuerxuntayi, Wenhui Shi, Tian Shi, Kudelaiti Abudukelimu, Beiyao Gao, Paziliya Abulaiti, Kailibinuer Nuermaimaiti, Najimangu Rehemutula, Shenglong Xue, Yingying Xing, Weidong Liu, Zhuoshuyi Liu, Jiangwei Liu, Feng Gao. Paeoniflorin attenuates ASA-induced enteropathy in simulated high-altitude hypoxia in rats by regulating intestinal inflammation, intestinal barrier, and intestinal flora. Toxicology and Applied Pharmacology 2026; 506 doi: 10.1016/j.taap.2025.117641
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| 52 |
Sneha Singh, Mairaj Ahmed Ansari. High Altitude Sickness – Solutions from Genomics, Proteomics and Antioxidant Interventions. 2022; doi: 10.1007/978-981-19-1008-1_3
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| 53 |
David Vearrier, Michael I. Greenberg. Occupational health of miners at altitude: Adverse health effects, toxic exposures, pre-placement screening, acclimatization, and worker surveillance. Clinical Toxicology 2011; 49(7) doi: 10.3109/15563650.2011.607169
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| 54 |
Xingchen Liao, Xuexin Wang, Xin Wang, Mingjie Zhang, Fangli Ren, Dezhi Wang, Jianqiu Sheng. Alterations in the gastric and small intestinal microbiota of mice exposed to short-term and long-term hypoxia. Scientific Reports 2025; 15(1) doi: 10.1038/s41598-025-26859-4
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| 55 |
Aditya Arya, Sneha Singh, Amit Kumar. Smart Nanomaterials Targeting Pathological Hypoxia. Smart Nanomaterials Technology 2023; doi: 10.1007/978-981-99-1718-1_21
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| 56 |
Peiwen Wu, Xun Li, Wenjie Long, Yu Ma, Bo Xue, Wen Xie, Xin Ma. The gut–kidney axis in high-altitude hypoxia: pathophysiological mechanisms and the central role of hypoxia inducible factor. Annals of Medicine 2025; 57(1) doi: 10.1080/07853890.2025.2557514
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| 57 |
Qiaorong Ji, Yu Zhang, Yiling Zhou, Mohammed Gamah, Zhouyang Yuan, Jie Liu, Chengzhu Cao, Xiang Gao, Huan Zhang, Yanming Ren, Wei Zhang. Effects of hypoxic exposure on immune responses of intestinal mucosa to Citrobacter colitis in mice. Biomedicine & Pharmacotherapy 2020; 129 doi: 10.1016/j.biopha.2020.110477
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| 58 |
Kunjan Khanna, K P Mishra, Lilly Ganju, Bhuvnesh Kumar, Shashi Bala Singh. High-Altitude-Induced alterations in Gut-Immune Axis: A review. International Reviews of Immunology 2018; 37(2) doi: 10.1080/08830185.2017.1407763
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| 59 |
Yuhao Wang, Yi Shi, Wenhao Li, Shu Wang, Jiyang Zheng, Guanghui Xu, Guixiang Li, Xuefeng Shen, Jianjun Yang. Gut microbiota imbalance mediates intestinal barrier damage in high‐altitude exposed mice. The FEBS Journal 2022; 289(16) doi: 10.1111/febs.16409
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| 60 |
Jyotsana Bakshi, K.P. Mishra. Sodium butyrate prevents lipopolysaccharide induced inflammation and restores the expression of tight junction protein in human epithelial Caco-2 cells. Cellular Immunology 2025; 408 doi: 10.1016/j.cellimm.2024.104912
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| 61 |
Juan Xiong, Hui Lu, Rong Wang, Zhengping Jia, Robert K Hills. Efficacy of ibuprofen on prevention of high altitude headache: A systematic review and meta-analysis. PLOS ONE 2017; 12(6) doi: 10.1371/journal.pone.0179788
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| 62 |
Zachary J. McKenna, Zachary J. Fennel, Quint N. Berkemeier, Roberto C. Nava, Fabiano T. Amorim, Michael R. Deyhle, Christine M. Mermier. Exercise in hypobaric hypoxia increases markers of intestinal injury and symptoms of gastrointestinal distress. Experimental Physiology 2022; 107(4) doi: 10.1113/EP090266
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| 63 |
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| 64 |
Mei Yang, Zhanting Yang, Yongfang Li, Shanshan Su, Zhanqiang Li, Dianxiang Lu, Taiyoun Rhim. Mechanism of Traditional Tibetan Medicine Grubthobrildkr Alleviated Gastric Ulcer Induced by Acute Systemic Hypoxia in Rats. BioMed Research International 2022; 2022(1) doi: 10.1155/2022/4803956
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| 65 |
Zi-xia Wang, Peng-peng Li, Cheng-nan Li, Yi-na Guo, Ya-zhou Shao, Qiao Yan, Long-xia Wen, Yan-ping Wang, Fang-Di Hu. Study on the mechanism of Codonopsis pilosula polysaccharide inhibiting gastric cancer precancerous lesions by regulating Wnt/β-catenin signaling pathway. Pharmacological Research - Modern Chinese Medicine 2024; 10 doi: 10.1016/j.prmcm.2024.100391
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| 66 |
Vijay Sharma, Lalit Singh. Navigating Innovations and Challenges in Travel Medicine and Digital Health. 2025; doi: 10.4018/979-8-3693-8774-0.ch024
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| 67 |
Paziliya Abulaiti, Wen Hui Shi, Huan Liu, Ailifeire Tuerxuntayi, Kailibinuer Nuermaimaiti, Zhuo Shuyi Liu, Yingying Xing, Najimangu Rehemutula, Kudelaiti Abdukelimu, Weidong Liu, Jiang Wei Liu, Feng Gao. Resveratrol mitigates aspirin-induced intestinal injury in rats in a high-altitude hypoxic environment associated with reducing the expression levels of angiotensin II. BMC Gastroenterology 2025; 25(1) doi: 10.1186/s12876-025-04248-5
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| 68 |
Esra POLAT, İbrahim Halil İNANÇ, Cengiz ŞABANOĞLU. The effect of altitude difference on gastrointestinal bleeding in the chronic period. Journal of Health Sciences and Medicine 2022; 5(2) doi: 10.32322/jhsm.1033697
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| 69 |
Stephan Vavricka, Pedro A Ruiz, Sylvie Scharl, Luc Biedermann, Michael Scharl, Cheryl de Vallière, Carsten Lundby, Roland H Wenger, Leonhard Held, Tobias M Merz, Max Gassmann, Thomas Lutz, Andres Kunz, Denis Bron, Adriano Fontana, Laura Strauss, Achim Weber, Michael Fried, Gerhard Rogler, Jonas Zeitz. Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study. BMJ Open 2017; 7(1) doi: 10.1136/bmjopen-2016-013477
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