| For: | Thong-Ngam D, Samuhasaneeto S, Kulaputana O, Klaikeaw N. N-acetylcysteine attenuates oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis. World J Gastroenterol 2007; 13(38): 5127-5132 [PMID: 17876880 DOI: 10.3748/wjg.v13.i38.5127] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v13/i38/5127.htm |
| Number | Citing Articles |
| 1 |
Sofie M.A. Walenbergh, Ger H. Koek, Veerle Bieghs, Ronit Shiri-Sverdlov. Non-alcoholic steatohepatitis: The role of oxidized low-density lipoproteins. Journal of Hepatology 2013; 58(4) doi: 10.1016/j.jhep.2012.11.014
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| 2 |
Nesrine Semiane, Fabienne Foufelle, Pascal Ferré, Isabelle Hainault, Souad Ameddah, Aicha Mallek, Ali Khalkhal, Yasmina Dahmani. High carbohydrate diet induces nonalcoholic steato-hepatitis (NASH) in a desert gerbil
. Comptes Rendus. Biologies 2016; 340(1) doi: 10.1016/j.crvi.2016.09.002
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| 3 |
Tania E. Schwingel, Caroline P. Klein, Natalia F. Nicoletti, Cristiana L. Dora, Gabriela Hadrich, Cláudia G. Bica, Tiago G. Lopes, Vinicius Duval da Silva, Fernanda B. Morrone. Effects of the compounds resveratrol, rutin, quercetin, and quercetin nanoemulsion on oxaliplatin-induced hepatotoxicity and neurotoxicity in mice. Naunyn-Schmiedeberg's Archives of Pharmacology 2014; 387(9) doi: 10.1007/s00210-014-0994-0
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| 4 |
Wei Cen, Ralph Hoppe, Rongbo Lu, Zhaoquan Cai, Ning Gu. 3D highly heterogeneous thermal model of pineal gland in-vitro study for electromagnetic exposure using finite volume method. AIP Advances 2017; 7(8) doi: 10.1063/1.4991464
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| 5 |
Ashwag H. Alwadani, Soheir A. Almasri, Amal A. Aloud, Nawal A. Albadr, Ghedeir M. Alshammari, Mohammed Abdo Yahya. The Synergistic Protective Effect of γ-Oryzanol (OZ) and N-Acetylcysteine (NAC) against Experimentally Induced NAFLD in Rats Entails Hypoglycemic, Antioxidant, and PPARα Stimulatory Effects. Nutrients 2022; 15(1) doi: 10.3390/nu15010106
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| 6 |
Gvozden Rosic, Dragica Selakovic, Jovana Joksimovic, Ivan Srejovic, Vladimir Zivkovic, Nikola Tatalović, Zorana Orescanin-Dusic, Slobodanka Mitrovic, Milena Ilic, Vladimir Jakovljevic. The effects of N-acetylcysteine on cisplatin-induced changes of cardiodynamic parameters within coronary autoregulation range in isolated rat hearts. Toxicology Letters 2016; 242 doi: 10.1016/j.toxlet.2015.11.028
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| 7 |
Sebastião Mauro Bezerra DUARTE, José Tadeu STEFANO, Denise Siqueira VANNI, Flair José CARRILHO, Claudia Pinto Marques Souza de OLIVEIRA. IMPACT OF CURRENT DIET AT THE RISK OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD). Arquivos de Gastroenterologia 2019; 56(4) doi: 10.1590/s0004-2803.201900000-67
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| 8 |
Haihua Huo, Haitong Wu, Feiyang Ma, Xinrun Li, Jianzhao Liao, Lianmei Hu, Qingyue Han, Ying Li, Jiaqiang Pan, Hui Zhang, Zhaoxin Tang, Jianying Guo. N-acetyl-L-cysteine ameliorates hepatocyte pyroptosis of dog type 1 diabetes mellitus via suppression of NLRP3/NF-κB pathway. Life Sciences 2022; 306 doi: 10.1016/j.lfs.2022.120802
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| 9 |
Reza Heidari. The footprints of mitochondrial impairment and cellular energy crisis in the pathogenesis of xenobiotics-induced nephrotoxicity, serum electrolytes imbalance, and Fanconi’s syndrome: A comprehensive review. Toxicology 2019; 423 doi: 10.1016/j.tox.2019.05.002
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| 10 |
Özlem Coşkun, Özlem Öztopuz, Başak Büyük. Possible protective activity of n-acetyl cysteine against cisplatin‑induced hepatotoxicity in rats. Molecular Biology Reports 2021; 48(1) doi: 10.1007/s11033-020-06111-0
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| 11 |
Akiko Sakasai-Sakai, Takanobu Takata, Masayoshi Takeuchi. Intracellular Toxic Advanced Glycation End-Products Promote the Production of Reactive Oxygen Species in HepG2 Cells. International Journal of Molecular Sciences 2020; 21(14) doi: 10.3390/ijms21144861
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| 12 |
Mariapia Vairetti, Laura Giuseppina Di Pasqua, Marta Cagna, Plinio Richelmi, Andrea Ferrigno, Clarissa Berardo. Changes in Glutathione Content in Liver Diseases: An Update. Antioxidants 2021; 10(3) doi: 10.3390/antiox10030364
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| 13 |
D. Gutiérrez-Praena, M.A. Risalde, S. Pichardo, A. Jos, R. Moyano, A. Blanco, V. Vasconcelos, A.M. Cameán. Histopathological and immunohistochemical analysis of Tilapia (Oreochromis niloticus) exposed to cylindrospermopsin and the effectiveness of N-Acetylcysteine to prevent its toxic effects. Toxicon 2014; 78 doi: 10.1016/j.toxicon.2013.11.014
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| 14 |
Steven Tun, Caleb James Spainhower, Cameron Lee Cottrill, Hari Vishal Lakhani, Sneha S. Pillai, Anum Dilip, Hibba Chaudhry, Joseph I. Shapiro, Komal Sodhi. Therapeutic Efficacy of Antioxidants in Ameliorating Obesity Phenotype and Associated Comorbidities. Frontiers in Pharmacology 2020; 11 doi: 10.3389/fphar.2020.01234
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| 15 |
Lidianys María Lewis Lujan, Mark F. McCarty, Juan Carlos Galvez Ruiz, Sergio Trujillo Lopez, Simon Bernard Iloki-Assanga. Nutraceutical and dietary measures with potential for preventing/controlling non-alcoholic fatty liver disease and its complications. Human Nutrition & Metabolism 2024; 37 doi: 10.1016/j.hnm.2024.200281
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| 16 |
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| 17 |
Rossella Donghia, Angelo Campanella, Caterina Bonfiglio, Francesco Cuccaro, Rossella Tatoli, Gianluigi Giannelli. Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study. Nutrients 2024; 16(4) doi: 10.3390/nu16040562
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| 18 |
Hadjer Agoun, Nesrine Semiane, Aicha Mallek, Zineb Bellahreche, Soumia Hammadi, Maha Madjerab, Mohamed Abdlalli, Ali Khalkhal, Yasmina Dahmani. High-carbohydrate diet-induced metabolic disorders in Gerbillus tarabuli (a new model of non-alcoholic fatty-liver disease). Protective effects of 20-hydroxyecdysone. Archives of Physiology and Biochemistry 2021; 127(2) doi: 10.1080/13813455.2019.1621350
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| 19 |
Jonathan Jun, Vladimir Savransky, Ashika Nanayakkara, Shannon Bevans, Jianguo Li, Philip L. Smith, Vsevolod Y. Polotsky. Intermittent hypoxia has organ-specific effects on oxidative stress. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2008; 295(4) doi: 10.1152/ajpregu.90346.2008
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| 20 |
Fatma Genç, Emine Gülçeri GÜLEÇ Peker. Does Short-Term and Low-Dose N-Acetylcysteine Affect Oxidative Stress and Inflammation in The Liver Tissues of Diabetic Rats?. Biological Research For Nursing 2021; 23(4) doi: 10.1177/10998004211003668
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| 21 |
Mohamed Montassar Lasram, Ines Bini Dhouib, Alya Annabi, Saloua El Fazaa, Najoua Gharbi. A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development. Clinical Biochemistry 2015; 48(16-17) doi: 10.1016/j.clinbiochem.2015.04.017
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| 22 |
Apu Chowdhury, Jahan Nabila, Isaac Adelusi Temitope, Sicen Wang. Current etiological comprehension and therapeutic targets of acetaminophen-induced hepatotoxicity. Pharmacological Research 2020; 161 doi: 10.1016/j.phrs.2020.105102
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| 23 |
Hua Shen, Miao Li, Bingxuan Wang, Ian K. Lai, Larry W. Robertson, Gabriele Ludewig. Dietary antioxidants (selenium and N-acetylcysteine) modulate paraoxonase 1 (PON1) in PCB 126-exposed rats. Environmental Science and Pollution Research 2014; 21(10) doi: 10.1007/s11356-013-1690-1
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| 24 |
Alfredo Fernández-Quintela, Marcela González, Leixuri Aguirre, Iñaki Milton-Laskibar, Asier Léniz, Maria P. Portillo. The Liver. 2018; doi: 10.1016/B978-0-12-803951-9.00017-3
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| 25 |
Kristiane Yacou Dunbar, Gezelle Dali, Marilena M. DeMayo, Warren Logge, Tristan Hurzeler, Catherine Kelly, Joshua Watt, Lindsay M. Squeglia, Anna E. Kirkland, Paul S. Haber, Kirsten C. Morley. The Effect of N‐Acetylcysteine (NAC) on Neurometabolites and Cognitive Function in Adults With Alcohol Use Disorder: A Preliminary Randomized Controlled Trial. Neuropsychopharmacology Reports 2025; 45(4) doi: 10.1002/npr2.70066
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| 26 |
Tiantian Jia, Penghui Nie, Hengyi Xu. Combined exposure of nano‐titanium dioxide and polystyrene nanoplastics exacerbate oxidative stress‐induced liver injury in mice by regulating the Keap‐1/Nrf2/ARE pathway. Environmental Toxicology 2024; 39(5) doi: 10.1002/tox.24141
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| 27 |
Mohamed Ibrahim, Entesar Farghaly, Wafaey Gomaa, Mina Kelleni, Aly Mohamed Abdelrahman. Nitro-aspirin is a potential therapy for non alcoholic fatty liver disease. European Journal of Pharmacology 2011; 659(2-3) doi: 10.1016/j.ejphar.2011.03.016
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| 28 |
N. Lohvinenko, V. Shvets, G. Berest, I. Nosulenko, O. Voskoboinik, H. Severina, S. Okovytyy, S. Kovalenko. Prospects for the use of sulfur-containing pteridines in toxic liver damage . Regulatory Mechanisms in Biosystems 2024; 15(2) doi: 10.15421/022453
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| 29 |
Milka Mileva, Adriana Dimitrova-Koleva, Elina Tsvetanova, Dimo Krastev, Almira Georgieva, Albena Alexandrova, Angel Galabov. Mitigation of the Oxidative Damage in Liver Caused by Influenza Virus Infection in Mice by an Effective Combination of Oseltamivir and S-adenosyl-L-methionine (SAM). Journal of Pharmacy and Nutrition Sciences 2022; 12 doi: 10.29169/1927-5951.2022.12.11
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| 30 |
A. Y. Au, J. M. Hasenwinkel, C. G. Frondoza. Hepatoprotective effects of S‐adenosylmethionine and silybin on canine hepatocytes in vitro. Journal of Animal Physiology and Animal Nutrition 2013; 97(2) doi: 10.1111/j.1439-0396.2012.01275.x
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| 31 |
Mohammad Mehdi Ommati, Akram Jamshidzadeh, Hossein Niknahad, Hamidreza Mohammadi, Samira Sabouri, Reza Heidari, Narges Abdoli. N-acetylcysteine treatment blunts liver failure-associated impairment of locomotor activity. PharmaNutrition 2017; 5(4) doi: 10.1016/j.phanu.2017.10.003
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| 32 |
Raquel Ordoñez, Sara Carbajo‐Pescador, Néstor Prieto‐Dominguez, Andrés García‐Palomo, Javier González‐Gallego, José L. Mauriz. Inhibition of matrix metalloproteinase‐9 and nuclear factor kappa B contribute to melatonin prevention of motility and invasiveness in HepG2 liver cancer cells. Journal of Pineal Research 2014; 56(1) doi: 10.1111/jpi.12092
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| 33 |
Mohamed Montassar Lasram, Aicha Jrad Lamine, Ines Bini Dhouib, Kahena Bouzid, Alya Annabi, Nadia Belhadjhmida, Malika Ben Ahmed, Saloua El Fazaa, Jaouida Abdelmoula, Najoua Gharbi. Antioxidant and anti-inflammatory effects of N-acetylcysteine against malathion-induced liver damages and immunotoxicity in rats. Life Sciences 2014; 107(1-2) doi: 10.1016/j.lfs.2014.04.033
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| 34 |
Mark F. McCarty. Full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease. Medical Hypotheses 2011; 77(4) doi: 10.1016/j.mehy.2011.06.029
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| 35 |
Puiyan Lam, Fan Cheung, Hor Tan, Ning Wang, Man Yuen, Yibin Feng. Hepatoprotective Effects of Chinese Medicinal Herbs: A Focus on Anti-Inflammatory and Anti-Oxidative Activities. International Journal of Molecular Sciences 2016; 17(4) doi: 10.3390/ijms17040465
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| 36 |
Amir Hajighasem, Parvin Farzanegi, Zohreh Mazaheri. Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis, oxidative stress, and inflammatory biomarkers in the liver of old rats with non-alcoholic fatty liver disease. Archives of Physiology and Biochemistry 2019; 125(2) doi: 10.1080/13813455.2018.1441872
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| 37 |
Shuai Huang, Jian You, Kun Wang, Yueqiang Li, Ying Zhang, Haotian Wei, Xinjun Liang, Yanyan Liu. N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor. BioMed Research International 2019; 2019 doi: 10.1155/2019/4805853
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| 38 |
Pochuen Shieh, Chung-Ren Jan, Wei-Zhe Liang. The protective effects of the antioxidant N-acetylcysteine (NAC) against oxidative stress-associated apoptosis evoked by the organophosphorus insecticide malathion in normal human astrocytes. Toxicology 2019; 417 doi: 10.1016/j.tox.2019.02.004
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| 39 |
Rhea Mehta, Lilian Wong, Peter J. O’Brien. Cytoprotective mechanisms of carbonyl scavenging drugs in isolated rat hepatocytes. Chemico-Biological Interactions 2009; 178(1-3) doi: 10.1016/j.cbi.2008.10.026
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| 40 |
Doaa I. Mohamed, Eman Khairy, Sara A. Khedr, Eman K. Habib, Wael M. Elayat, Omnyah A. El-kharashi. N-acetylcysteine (NAC) alleviates the peripheral neuropathy associated with liver cirrhosis via modulation of neural MEG3/PAR2/ NF-ҡB axis. Neurochemistry International 2020; 132 doi: 10.1016/j.neuint.2019.104602
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| 41 |
Hujun Xie, Xin Luo, Ying Gao, Min Huang, Gerui Ren, Rongmi Zhou, Yulu Sun, Haoxin Ye, Qunfang Lei, Wenjun Fang, Yong-Quan Xu. Co-encapsulation of Lactobacillus plantarum and EGCG: A promising strategy to increase the stability and lipid-lowering activity. Food Hydrocolloids 2024; 151 doi: 10.1016/j.foodhyd.2024.109768
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| 42 |
Cristina Bernal, Gala Martín-Pozuelo, Ana B. Lozano, Ángel Sevilla, Javier García-Alonso, Manuel Canovas, María J. Periago. Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis. The Journal of Nutritional Biochemistry 2013; 24(11) doi: 10.1016/j.jnutbio.2013.05.003
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| 43 |
Miguel Vázquez-Velasco, Laura González-Torres, Rosa A. García-Fernández, María Teresa Méndez, Sara Bastida, Juana Benedí, María José González-Muñoz, Francisco J. Sánchez-Muniz. Glucomannan or Glucomannan Plus Spirulina-Enriched Squid-Surimi Diets Reduce Histological Damage to Liver and Heart in Zucker fa/fa Rats Fed a Cholesterol-Enriched and Non-Cholesterol-Enriched Atherogenic Diet. Journal of Medicinal Food 2017; 20(6) doi: 10.1089/jmf.2016.0157
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| 44 |
Ahmed Attia, Ahmed Ragheb, Thomas Sylwestrowicz, Ahmed Shoker. Attenuation of high cholesterol-induced oxidative stress in rabbit liver by thymoquinone. European Journal of Gastroenterology & Hepatology 2010; 22(7) doi: 10.1097/MEG.0b013e328336000d
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| 45 |
Indrani Sinha-Hikim, Amiya P. Sinha-Hikim, Ruoqing Shen, H. Kim, Samuel W. French, Nosratola D. Vaziri, Albert Crum, Tripathi B. Rajavashisth, Keith C. Norris. A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. Experimental and Molecular Pathology 2011; 91(1) doi: 10.1016/j.yexmp.2011.04.009
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| 46 |
Tingting Shi, Li Wu, Wenjun Ma, Liping Ju, Minghui Bai, Xiaowei Chen, Shourong Liu, Xingxin Yang, Junping Shi, Svein Haavik. Nonalcoholic Fatty Liver Disease: Pathogenesis and Treatment in Traditional Chinese Medicine and Western Medicine. Evidence-Based Complementary and Alternative Medicine 2020; 2020(1) doi: 10.1155/2020/8749564
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| 47 |
Eden Yonatan, Orya Noa Shukha, Idit Golani, Saher Abu-ata, Yaseen Awad-Igbaria, Nizar Khatib, Yuval Ginsberg, Eilam Palzur, Ron Beloosesky, Alon Shamir. Maternal N-acetylcysteine supplementation in lactation ameliorates metabolic and cognitive deficits in adult offspring exposed to maternal obesity. Neuropharmacology 2025; 271 doi: 10.1016/j.neuropharm.2025.110390
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| 48 |
Phiwayinkosi V. Dludla, Bongani B. Nkambule, Sithandiwe E. Mazibuko-Mbeje, Tawanda M. Nyambuya, Fabio Marcheggiani, Ilenia Cirilli, Khanyisani Ziqubu, Samukelisiwe C. Shabalala, Rabia Johnson, Johan Louw, Elisabetta Damiani, Luca Tiano. N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature. Antioxidants 2020; 9(12) doi: 10.3390/antiox9121283
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| 49 |
Kívia De Andrade, Fabiana Moura, John Dos Santos, Orlando De Araújo, Juliana De Farias Santos, Marília Goulart. Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine. International Journal of Molecular Sciences 2015; 16(12) doi: 10.3390/ijms161226225
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| 50 |
January N. Baumgardner, Kartik Shankar, Leah Hennings, Emanuele Albano, Thomas M. Badger, Martin J.J. Ronis. N-Acetylcysteine Attenuates Progression of Liver Pathology in a Rat Model of Nonalcoholic Steatohepatitis3. The Journal of Nutrition 2008; 138(10) doi: 10.1093/jn/138.10.1872
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| 51 |
G.H. Koek, P.R. Liedorp, A. Bast. The role of oxidative stress in non-alcoholic steatohepatitis. Clinica Chimica Acta 2011; 412(15-16) doi: 10.1016/j.cca.2011.04.013
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| 52 |
Luis Bujanda, Elizabeth Hijona, Mikel Larzabal, Marta Beraza, Pablo Aldazabal, Nerea García-Urkia, Cristina Sarasqueta, Angel Cosme, Belen Irastorza, Alberto González, Juan I Arenas. Resveratrol inhibits nonalcoholic fatty liver disease in rats. BMC Gastroenterology 2008; 8(1) doi: 10.1186/1471-230X-8-40
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| 53 |
Sha Li, Ming Hong, Hor-Yue Tan, Ning Wang, Yibin Feng, Karina Reyes-Gordillo. Insights into the Role and Interdependence of Oxidative Stress and Inflammation in Liver Diseases. Oxidative Medicine and Cellular Longevity 2016; 2016(1) doi: 10.1155/2016/4234061
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| 54 |
Shadi Mohammadpour-Asl, Alireza Shirpoor, Shahriar Alipour, Roya Naderi. Nandrolone decanoate induces liver damage via TGF-β/Smad3/miR-29 and regulation of FAT/CD36, PTP1B, HNF4A expression in male rats: Rescue effect of N-acetylcysteine. The Journal of Steroid Biochemistry and Molecular Biology 2026; 256 doi: 10.1016/j.jsbmb.2025.106902
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| 55 |
Gala Martín-Pozuelo, Inmaculada Navarro-González, Rocío González-Barrio, Marina Santaella, Javier García-Alonso, Nieves Hidalgo, Carlos Gómez-Gallego, Gaspar Ros, María Jesús Periago. The effect of tomato juice supplementation on biomarkers and gene expression related to lipid metabolism in rats with induced hepatic steatosis. European Journal of Nutrition 2015; 54(6) doi: 10.1007/s00394-014-0770-4
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| 56 |
Qinchao Ding, Rui Guo, Liuhua Pei, Shanglei Lai, Jiaomei Li, Yujie Yin, Tiantian Xu, Wenwen Yang, Qing Song, Qiang Han, Xiaobing Dou, Songtao Li. N-Acetylcysteine alleviates high fat diet-induced hepatic steatosis and liver injuryviaregulating the intestinal microecology in mice. Food & Function 2022; 13(6) doi: 10.1039/D1FO03952K
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| 57 |
Wenwen Yang, Rui Guo, Aiwen Pi, Qinchao Ding, Liuyi Hao, Qing Song, Lin Chen, Xiaobing Dou, Lixin Na, Songtao Li. Long non-coding RNA-EN_181 potentially contributes to the protective effects of N-acetylcysteine against non-alcoholic fatty liver disease in mice. British Journal of Nutrition 2023; 129(6) doi: 10.1017/S0007114522001829
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| 58 |
Mariana Verdelho Machado, Leandi Kruger, Mark L. Jewell, Gregory Alexander Michelotti, Thiago de Almeida Pereira, Guanhua Xie, Cynthia A. Moylan, Anna Mae Diehl. Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model. Digestive Diseases and Sciences 2016; 61(1) doi: 10.1007/s10620-015-3871-x
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| 59 |
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| 60 |
S Carbajo-Pescador, C Steinmetz, A Kashyap, S Lorenz, J L Mauriz, M Heise, P R Galle, J González-Gallego, S Strand. Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells. British Journal of Cancer 2013; 108(2) doi: 10.1038/bjc.2012.563
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| 61 |
Osman Tiryakioglu, Kamuran Erkoc, Bulent Tunerir, Onur Uysal, H. Firat Altin, Tevfik Gunes, Selim Aydin. The Effect of Iloprost and N-Acetylcysteine on Skeletal Muscle Injury in an Acute Aortic Ischemia-Reperfusion Model: An Experimental Study. BioMed Research International 2015; 2015 doi: 10.1155/2015/453748
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| 62 |
Claudia P OLIVEIRA, Helma P COTRIM, Jose Tadeu STEFANO, Ana Cristina G SIQUEIRA, Ana Lucia Azevedo SALGADO, Edison Roberto PARISE. N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL. Arquivos de Gastroenterologia 2019; 56(2) doi: 10.1590/s0004-2803.201900000-36
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