For: | Bangoura G, Liu ZS, Qian Q, Jiang CQ, Yang GF, Jing S. Prognostic significance of HIF-2α/EPAS1 expression in hepatocellular carcinoma. World J Gastroenterol 2007; 13(23): 3176-3182 [PMID: 17589895 DOI: 10.3748/wjg.v13.i23.3176] |
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URL: | https://www.wjgnet.com/1007-9327/full/v13/i23/3176.htm |
Number | Citing Articles |
1 |
Cynthia Ju, Sean P. Colgan, Holger K. Eltzschig. Hypoxia-inducible factors as molecular targets for liver diseases. Journal of Molecular Medicine 2016; 94(6): 613 doi: 10.1007/s00109-016-1408-1
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2 |
Hui Wang, Heng Jiang, Melissa Van De Gucht, Mark De Ridder. Hypoxic Radioresistance: Can ROS Be the Key to Overcome It?. Cancers 2019; 11(1): 112 doi: 10.3390/cancers11010112
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3 |
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4 |
Barbara Chiavarina, Ubaldo E. Martinez-Outschoorn, Diana Whitaker-Menezes, Anthony Howell, Herbert B. Tanowitz, Richard G. Pestell, Federica Sotgia, Michael P. Lisanti. Metabolic reprogramming and two-compartment tumor metabolism. Cell Cycle 2012; 11(17): 3280 doi: 10.4161/cc.21643
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5 |
Theresa Geis, Claudia Döring, Rüdiger Popp, Nina Grossmann, Ingrid Fleming, Martin-Leo Hansmann, Nathalie Dehne, Bernhard Brüne. HIF-2alpha-dependent PAI-1 induction contributes to angiogenesis in hepatocellular carcinoma. Experimental Cell Research 2015; 331(1): 46 doi: 10.1016/j.yexcr.2014.11.018
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6 |
Bharath Nath, Gyongyi Szabo. Hypoxia and Hypoxia Inducible Factors: Diverse Roles in Liver Diseases. Hepatology 2012; 55(2): 622 doi: 10.1002/hep.25497
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7 |
Stefania Cannito, Beatrice Foglia, Gianmarco Villano, Cristian Turato, Teresa C Delgado, Elisabetta Morello, Fabrizio Pin, Erica Novo, Lucia Napione, Santina Quarta, Mariagrazia Ruvoletto, Silvano Fasolato, Giacomo Zanus, Sebastiano Colombatto, Fernando Lopitz-Otsoa, David Fernández-Ramos, Federico Bussolino, Salvatore Sutti, Emanuele Albano, Maria Luz Martínez-Chantar, Patrizia Pontisso, Maurizio Parola. SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets. Cancers 2019; 11(12): 1933 doi: 10.3390/cancers11121933
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8 |
Cong Li, Hua-Jun Lu, Fei-Fei Na, Lei Deng, Jian-Xin Xue, Jing-Wen Wang, Yu-Qing Wang, Qiao-Ling Li, You Lu. Prognostic Role of Hypoxic Inducible Factor Expression in Non-small Cell Lung Cancer: A Meta-analysis. Asian Pacific Journal of Cancer Prevention 2013; 14(6): 3607 doi: 10.7314/APJCP.2013.14.6.3607
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9 |
Zihao Li, Bing Yin, Yanan Xu, Chaoqun Wang, Xinglong Li, Shounan Lu, Shanjia Ke, Baolin Qian, Hongjun Yu, Miaoyu Bai, Zhongyu Li, Yongzhi Zhou, Hongchi Jiang, Yong Ma. Von Hippel-Lindau deficiency protects the liver against ischemia/reperfusion injury through the regulation of hypoxia-inducible factor 1α and 2α. Hepatology Communications 2024; 8(12) doi: 10.1097/HC9.0000000000000567
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10 |
Heidi Menrad, Christian Werno, Tobias Schmid, Ekaterini Copanaki, Thomas Deller, Nathalie Dehne, Bernhard Brüne. Roles of Hypoxia-Inducible Factor-1α (Hif-1α) Versus Hif-2α in the Survival of Hepatocellular Tumor Spheroids. Hepatology 2010; 51(6): 2183 doi: 10.1002/hep.23597
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11 |
Han Mu, Ge Yu, Huikai Li, Mengmeng Wang, Yunlong Cui, Ti Zhang, Tianqiang Song, Changfu Liu. Mild chronic hypoxia-induced HIF-2α interacts with c-MYC through competition with HIF-1α to induce hepatocellular carcinoma cell proliferation. Cellular Oncology 2021; 44(5): 1151 doi: 10.1007/s13402-021-00625-w
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12 |
S.-L. Yang, L.-P. Liu, J.-X. Jiang, Z.-F. Xiong, Q.-J. He, C. Wu. The Correlation of Expression Levels of HIF-1 and HIF-2 in Hepatocellular Carcinoma with Capsular Invasion, Portal Vein Tumor Thrombi and Patients' Clinical Outcome. Japanese Journal of Clinical Oncology 2014; 44(2): 159 doi: 10.1093/jjco/hyt194
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13 |
Sheng-li Yang, Li-ping Liu, Leilei Niu, Yun-fan Sun, Xing-rong Yang, Jia Fan, Jian-wei Ren, George G. Chen, Paul B.S. Lai. Downregulation and pro-apoptotic effect of hypoxia-inducible factor 2 alpha in hepatocellular carcinoma. Oncotarget 2016; 7(23): 34571 doi: 10.18632/oncotarget.8952
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14 |
Peppi Koivunen, Thomas Kietzmann. Hypoxia-Inducible Factor Prolyl 4-Hydroxylases and Metabolism. Trends in Molecular Medicine 2018; 24(12): 1021 doi: 10.1016/j.molmed.2018.10.004
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15 |
Jizhou Wang, Yong Ma, Hongchi Jiang, Huaqiang Zhu, Lianxin Liu, Bei Sun, Shangha Pan, Geoffrey W. Krissansen, Xueying Sun. Overexpression of von Hippel–Lindau protein synergizes with doxorubicin to suppress hepatocellular carcinoma in mice. Journal of Hepatology 2011; 55(2): 359 doi: 10.1016/j.jhep.2010.10.043
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16 |
Fei Ye, Yufang Che, Elizabeth McMillen, Justin Gorski, Douglas Brodman, Daisy Saw, Bo Jiang, David Y. Zhang. The Effect ofScutellaria Baicalensison the Signaling Network in Hepatocellular Carcinoma Cells. Nutrition and Cancer 2009; 61(4): 530 doi: 10.1080/01635580902803719
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17 |
Macus Hao-Ran Bao, Carmen Chak-Lui Wong. Hypoxia, Metabolic Reprogramming, and Drug Resistance in Liver Cancer. Cells 2021; 10(7): 1715 doi: 10.3390/cells10071715
|
18 |
E B Rankin, A J Giaccia. The role of hypoxia-inducible factors in tumorigenesis. Cell Death & Differentiation 2008; 15(4): 678 doi: 10.1038/cdd.2008.21
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19 |
Takayuki Shimizu, Ken-ichi Inoue, Hiroyuki Hachiya, Norisuke Shibuya, Mitsugi Shimoda, Keiichi Kubota. Frequent alteration of the protein synthesis of enzymes for glucose metabolism in hepatocellular carcinomas. Journal of Gastroenterology 2014; 49(9): 1324 doi: 10.1007/s00535-013-0895-x
|
20 |
Theresa Geis, Rüdiger Popp, Jiong Hu, Ingrid Fleming, Nina Henke, Nathalie Dehne, Bernhard Brüne. HIF‐2α attenuates lymphangiogenesis by up‐regulating IGFBP1 in hepatocellular carcinoma. Biology of the Cell 2015; 107(6): 175 doi: 10.1111/boc.201400079
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21 |
Hongjing Ma, Bin Liu, Shuoying Wang, Jing Liu. MicroRNA‐383 is a tumor suppressor in human lung cancer by targeting endothelial PAS domain‐containing protein 1. Cell Biochemistry and Function 2016; 34(8): 613 doi: 10.1002/cbf.3237
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22 |
Sergio Rey-Keim, Luana Schito. Origins and molecular effects of hypoxia in cancer. Seminars in Cancer Biology 2024; : 166 doi: 10.1016/j.semcancer.2024.10.001
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23 |
Aftab Ahmad, Shama Ahmad, Louise Glover, Stacy M. Miller, John M. Shannon, Xiaoling Guo, Wilbur A. Franklin, James P. Bridges, Jerome B. Schaack, Sean P. Colgan, Carl W. White.
Adenosine A
2A
receptor is a unique angiogenic target of HIF-2α in pulmonary endothelial cells
. Proceedings of the National Academy of Sciences 2009; 106(26): 10684 doi: 10.1073/pnas.0901326106
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24 |
Wanninayake M Tilakaratne, Eranga H Nissanka-Jayasuriya. Value of HIF-1α as an independent prognostic indicator in oral squamous cell carcinoma. Expert Review of Molecular Diagnostics 2011; 11(2): 145 doi: 10.1586/erm.11.2
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25 |
Mennatallah A. Khedr, Zainab Mohamed, Azza M. El-Derby, Malak M. Soliman, Amira Abdel Fattah Edris, Eman Badr, Nagwa El-Badri. Development of hepatocellular carcinoma organoid model recapitulating HIF-1A metabolic signature. Clinical and Experimental Medicine 2024; 25(1) doi: 10.1007/s10238-024-01521-x
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26 |
XINTING PAN, QINGYUN ZHU, YUNBO SUN, LIANDI LI, YUNPENG ZHU, ZHIHUI ZHAO, JIANXIN ZUO, WEI FANG, KUN LI. PLGA/poloxamer nanoparticles loaded with EPAS1 siRNA for the treatment of pancreatic cancer in vitro and in vivo. International Journal of Molecular Medicine 2015; 35(4): 995 doi: 10.3892/ijmm.2015.2096
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27 |
Carmen Chak-Lui Wong, Alan Ka-Lun Kai, Irene Oi-Lin Ng. The impact of hypoxia in hepatocellular carcinoma metastasis. Frontiers of Medicine 2014; 8(1): 33 doi: 10.1007/s11684-013-0301-3
|
28 |
Lionel Y.W. Leck, Yomna S. Abd El-Aziz, Kelly J. McKelvey, Kyung Chan Park, Sumit Sahni, Darius J.R. Lane, Jan Skoda, Patric J. Jansson. Cancer stem cells: Masters of all traits. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2025; 1871(3): 167549 doi: 10.1016/j.bbadis.2024.167549
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29 |
Margaux Deynoux, Nicola Sunter, Olivier Hérault, Frédéric Mazurier. Hypoxia and Hypoxia-Inducible Factors in Leukemias. Frontiers in Oncology 2016; 6 doi: 10.3389/fonc.2016.00041
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30 |
Jun Li, Yibo Yan, Ganxin Wang, Zaozao Huang. Hypoxia-inducible factor-2α and its missense mutations: potential role in HCC diagnosis, progression, and prognosis and underlying mechanism. Oncology and Translational Medicine 2022; 8(6): 267 doi: 10.1007/s10330-022-0598-8
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31 |
Stefania Cannito, Cristian Turato, Claudia Paternostro, Alessandra Biasiolo, Sebastiano Colombatto, Irene Cambieri, Santina Quarta, Erica Novo, Elisabetta Morello, Gianmarco Villano, Silvano Fasolato, Tiziana Musso, Ezio David, Ignazia Tusa, Elisabetta Rovida, Riccardo Autelli, Antonina Smedile, Umberto Cillo, Patrizia Pontisso, Maurizio Parola. Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells. Oncotarget 2015; 6(4): 2206 doi: 10.18632/oncotarget.2943
|
32 |
Zhao-Jia Gao, Yong Wang, Wei-dong Yuan, Jun-qiang Yuan, Kai Yuan. HIF-2α not HIF-1α overexpression confers poor prognosis in non–small cell lung cancer. Tumor Biology 2017; 39(6): 101042831770963 doi: 10.1177/1010428317709637
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33 |
Joaquín Araos, Jonathan P. Sleeman, Boyan K. Garvalov. The role of hypoxic signalling in metastasis: towards translating knowledge of basic biology into novel anti-tumour strategies. Clinical & Experimental Metastasis 2018; 35(7): 563 doi: 10.1007/s10585-018-9930-x
|
34 |
Vincent Wai-Hin Yuen, Carmen Chak-Lui Wong. Hypoxia-inducible factors and innate immunity in liver cancer. Journal of Clinical Investigation 2020; 130(10): 5052 doi: 10.1172/JCI137553
|
35 |
Minting Chen, Haitao Xiao, Baisen Chen, Zhaoxiang Bian, Hiu Yee Kwan. The advantages of using Scutellaria baicalensis and its flavonoids for the management of non-viral hepatocellular carcinoma. Journal of Functional Foods 2021; 78: 104389 doi: 10.1016/j.jff.2021.104389
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36 |
Meaghan Torvund, Jayati Chakrabarti, Yana Zavros. Inflammation, Infection, and Microbiome in Cancers. Physiology in Health and Disease 2021; : 155 doi: 10.1007/978-3-030-67951-4_6
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37 |
Irma Telarovic, Roland H. Wenger, Martin Pruschy. Interfering with Tumor Hypoxia for Radiotherapy Optimization. Journal of Experimental & Clinical Cancer Research 2021; 40(1) doi: 10.1186/s13046-021-02000-x
|
38 |
Chu Chen, Tao Lou. Hypoxia inducible factors in hepatocellular carcinoma. Oncotarget 2017; 8(28): 46691 doi: 10.18632/oncotarget.17358
|
39 |
Brian Keith, Randall S. Johnson, M. Celeste Simon. HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression. Nature Reviews Cancer 2012; 12(1): 9 doi: 10.1038/nrc3183
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40 |
Qi Zhang, Yu Lou, Jingying Zhang, Qihan Fu, Tao Wei, Xu Sun, Qi Chen, Jiaqi Yang, Xueli Bai, Tingbo Liang. Hypoxia-inducible factor-2α promotes tumor progression and has crosstalk with Wnt/β-catenin signaling in pancreatic cancer. Molecular Cancer 2017; 16(1) doi: 10.1186/s12943-017-0689-5
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41 |
Zuzana Rychtarcikova, Sandra Lettlova, Veronika Tomkova, Vlasta Korenkova, Lucie Langerova, Ekaterina Simonova, Polina Zjablovskaja, Meritxell Alberich-Jorda, Jiri Neuzil, Jaroslav Truksa. Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. Oncotarget 2017; 8(4): 6376 doi: 10.18632/oncotarget.14093
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42 |
Tingyan Zhong, Mengyun Wu, Shuangge Ma. Examination of Independent Prognostic Power of Gene Expressions and Histopathological Imaging Features in Cancer. Cancers 2019; 11(3): 361 doi: 10.3390/cancers11030361
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43 |
Min Wang, Mei-yuan Chen, Xing-jun Guo, Jian-xin Jiang. Expression and significance of HIF-1α and HIF-2α in pancreatic cancer. Journal of Huazhong University of Science and Technology [Medical Sciences] 2015; 35(6): 874 doi: 10.1007/s11596-015-1521-3
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44 |
Akifumi Kuwano, Masatake Tanaka, Hideo Suzuki, Miho Kurokawa, Koji Imoto, Shigeki Tashiro, Takeshi Goya, Motoyuki Kohjima, Masaki Kato, Yoshihiro Ogawa. Upregulated expression of hypoxia reactive genes in peripheral blood mononuclear cells from chronic liver disease patients. Biochemistry and Biophysics Reports 2021; 27: 101068 doi: 10.1016/j.bbrep.2021.101068
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45 |
Deqing Luo, Hui Liu, Dasheng Lin, Kejian Lian, Hongyue Ren. The Clinicopathologic and Prognostic Value of Hypoxia-Inducible Factor-2α in Cancer Patients: A Systematic Review and Meta-Analysis. Cancer Epidemiology, Biomarkers & Prevention 2019; 28(5): 857 doi: 10.1158/1055-9965.EPI-18-0881
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46 |
Hai-Xiang Sun, Yang Xu, Xin-Rong Yang, Wei-Min Wang, Haibo Bai, Ruo-Yu Shi, Suresh K. Nayar, Ranjan P. Devbhandari, Yi-zhou He, Qin-Feng Zhu, Yun-Fan Sun, Bo Hu, Mehtab Khan, Robert A. Anders, Jia Fan. Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1–dependent apoptotic pathway. Hepatology 2013; 57(3): 1088 doi: 10.1002/hep.26188
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47 |
Mingyang Ma, Shuyao Hua, Gang Li, Sumei Wang, Xue Cheng, Songqing He, Ping Wu, Xiaoping Chen. Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma. Oncotarget 2017; 8(8): 12983 doi: 10.18632/oncotarget.14677
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48 |
Jasper Wouters, Marguerite Stas, Lies Gremeaux, Olivier Govaere, Anke Van den broeck, Hannelore Maes, Patrizia Agostinis, Tania Roskams, Joost J. van den Oord, Hugo Vankelecom, Marc Tjwa. The Human Melanoma Side Population Displays Molecular and Functional Characteristics of Enriched Chemoresistance and Tumorigenesis. PLoS ONE 2013; 8(10): e76550 doi: 10.1371/journal.pone.0076550
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49 |
Luana Schito, Sergio Rey. Hypoxic pathobiology of breast cancer metastasis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2017; 1868(1): 239 doi: 10.1016/j.bbcan.2017.05.004
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50 |
Liliana Schaefer, Claudia Tredup, Maria A. Gubbiotti, Renato V. Iozzo. Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology. The FEBS Journal 2017; 284(1): 10 doi: 10.1111/febs.13963
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51 |
Aki Pui-Wah Tse, Karen Man-Fong Sze, Queenie Tsung-Kwan Shea, Elley Yung-Tuen Chiu, Felice Ho-Ching Tsang, David Kung-Chun Chiu, Misty Shuo Zhang, Derek Lee, Iris Ming-Jing Xu, Cerise Yuen-Ki Chan, Hui-Yu Koh, Chun-Ming Wong, Yong-Ping Zheng, Irene Oi-Lin Ng, Carmen Chak-Lui Wong. Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer. Oncogenesis 2018; 7(5) doi: 10.1038/s41389-018-0052-8
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52 |
Danele Hunecke, Reinhard Spanel, Florian Länger, Suk Woo Nam, Juergen Borlak. MYC‐regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer. The Journal of Pathology 2012; 228(4): 520 doi: 10.1002/path.4059
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53 |
Yingying Mao, Alan Fu, Derek Leaderer, Tongzhang Zheng, Kun Chen, Yong Zhu. Potential cancer-related role of circadian gene TIMELESS suggested by expression profiling and in vitro analyses. BMC Cancer 2013; 13(1) doi: 10.1186/1471-2407-13-498
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54 |
Xintong Ren, Xiaotong Diao, Jingjing Zhuang, Dalei Wu. Structural Basis for the Allosteric Inhibition of Hypoxia-Inducible Factor 2 by Belzutifan. Molecular Pharmacology 2022; 102(6): 240 doi: 10.1124/molpharm.122.000525
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55 |
Ainiwaer Talifu, Refuhati Saimaiti, Yusufu Maitinuer, Geyu Liu, Miernisha Abudureyimu, Xuelei Xin. Multiomics analysis profile acute liver injury module clusters to compare the therapeutic efficacy of bifendate and muaddil sapra. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-40356-5
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56 |
Rosa Quiles-Perez, José Antonio Muñoz-Gámez, Ángeles Ruiz-Extremera, Francisco O'Valle, Laura Sanjuán-Nuñez, Ana Belén Martín-Álvarez, David Martín-Oliva, Trinidad Caballero, Paloma Muñoz de Rueda, Josefa León, Raúl Gonzalez, Jordi Muntané, Francisco Javier Oliver, Javier Salmerón. Inhibition of Poly Adenosine Diphosphate-Ribose Polymerase Decreases Hepatocellular Carcinoma Growth by Modulation of Tumor-Related Gene Expression. Hepatology 2010; 51(1): 255 doi: 10.1002/hep.23249
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57 |
Manqing Cao, Junrong Gao, Hongyuan Zhou, Jiafei Huang, Abin You, Zhigui Guo, Feng Fang, Wei Zhang, Tianqiang Song, Ti Zhang. HIF-2α regulates CDCP1 to promote PKCδ-mediated migration in hepatocellular carcinoma. Tumor Biology 2016; 37(2): 1651 doi: 10.1007/s13277-015-3527-7
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58 |
Tommaso Mello, Irene Simeone, Andrea Galli. Mito-Nuclear Communication in Hepatocellular Carcinoma Metabolic Rewiring. Cells 2019; 8(5): 417 doi: 10.3390/cells8050417
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59 |
Celina Ang, Eileen M. O’Reilly, Ghassan K. Abou-Alfa. Multidisciplinary Treatment of Hepatocellular Carcinoma. Recent Results in Cancer Research 2013; 190: 225 doi: 10.1007/978-3-642-16037-0_15
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60 |
Xiu Lv, Jincheng Li, Chuhong Zhang, Tian Hu, Sai Li, Sha He, Hanxing Yan, Yixi Tan, Mingsheng Lei, Meiling Wen, Jianhong Zuo. The role of hypoxia-inducible factors in tumor angiogenesis and cell metabolism. Genes & Diseases 2017; 4(1): 19 doi: 10.1016/j.gendis.2016.11.003
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61 |
Carmen Oi-ning Leung, Carmen Chak-lui Wong, Dorothy Ngo-yin Fan, Alan Ka-lun Kai, Edmund Kwok-kwan Tung, Iris Ming-jing Xu, Irene Oi-lin Ng, Regina Cheuk-lam Lo. PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma. Oncotarget 2015; 6(13): 10880 doi: 10.18632/oncotarget.3534
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62 |
Vinit Singh Baghel, Sapnita Shinde, Vineeta Dixit, Naveen Kumar Vishvakarma, Atul Kumar Tiwari, Soumitra Tiwari, Dhananjay Shukla. Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 2. 2022; : 337 doi: 10.1016/B978-0-323-98807-0.00009-0
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63 |
Adam Myszczyszyn, Anna M. Czarnecka, Damian Matak, Lukasz Szymanski, Fei Lian, Anna Kornakiewicz, Ewa Bartnik, Wojciech Kukwa, Claudine Kieda, Cezary Szczylik. The Role of Hypoxia and Cancer Stem Cells in Renal Cell Carcinoma Pathogenesis. Stem Cell Reviews and Reports 2015; 11(6): 919 doi: 10.1007/s12015-015-9611-y
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64 |
Aleša Kristan, Nataša Debeljak, Tanja Kunej. Integration and Visualization of Regulatory Elements and Variations of the EPAS1 Gene in Human. Genes 2021; 12(11): 1793 doi: 10.3390/genes12111793
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J Zhao, F Du, G Shen, F Zheng, B Xu. The role of hypoxia-inducible factor-2 in digestive system cancers. Cell Death & Disease 2015; 6(1): e1600 doi: 10.1038/cddis.2014.565
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Liang Jiang, Qiu‑Long Liu, Qi‑Lian Liang, Hui‑Jie Zhang, Wen‑Ting Ou, Gao‑Le Yuan. Association of PHD3 and HIF2α gene expression with clinicopathological characteristics in human hepatocellular carcinoma. Oncology Letters 2017; doi: 10.3892/ol.2017.7302
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Eloy Moreno Roig, Ala Yaromina, Ruud Houben, Arjan J. Groot, Ludwig Dubois, Marc Vooijs. Prognostic Role of Hypoxia-Inducible Factor-2α Tumor Cell Expression in Cancer Patients: A Meta-Analysis. Frontiers in Oncology 2018; 8 doi: 10.3389/fonc.2018.00224
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Sonia Moniz, Daniel Bandarra, John Biddlestone, Kirsteen J. Campbell, David Komander, Anja Bremm, Sonia Rocha. Cezanne regulates E2F1-dependent HIF2α expression. Journal of Cell Science 2015; doi: 10.1242/jcs.168864
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Katjana Daskalow, Nadine Rohwer, Esther Raskopf, Evelyne Dupuy, Anja Kühl, Christoph Loddenkemper, Bertram Wiedenmann, Volker Schmitz, Thorsten Cramer. Role of hypoxia-inducible transcription factor 1α for progression and chemosensitivity of murine hepatocellular carcinoma. Journal of Molecular Medicine 2010; 88(8): 817 doi: 10.1007/s00109-010-0623-4
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Thomas Kietzmann. Liver Zonation in Health and Disease: Hypoxia and Hypoxia-Inducible Transcription Factors as Concert Masters. International Journal of Molecular Sciences 2019; 20(9): 2347 doi: 10.3390/ijms20092347
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S Whittaker, R Marais, A X Zhu. The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene 2010; 29(36): 4989 doi: 10.1038/onc.2010.236
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Alexander Laemmle, Antje Lechleiter, Vincent Roh, Christa Schwarz, Simone Portmann, Cynthia Furer, Adrian Keogh, Mario P. Tschan, Daniel Candinas, Stephan A. Vorburger, Deborah Stroka, Mikhail V. Blagosklonny. Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions. PLoS ONE 2012; 7(3): e33433 doi: 10.1371/journal.pone.0033433
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Jung Hwa Lim, Dae-Ghon Kim, Dae-Yeul Yu, Hyun Mi Kang, Kyung Hee Noh, Dae-Soo Kim, Dongmin Park, Tae Kyung Chang, Dong-Soo Im, Cho-Rok Jung. Stabilization of E2-EPF UCP protein is implicated in hepatitis B virus-associated hepatocellular carcinoma progression. Cellular and Molecular Life Sciences 2019; 76(13): 2647 doi: 10.1007/s00018-019-03066-9
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Cristian Turato, Stefania Cannito, Davide Simonato, Gianmarco Villano, Elisabetta Morello, Liliana Terrin, Santina Quarta, Alessandra Biasiolo, Mariagrazia Ruvoletto, Andrea Martini, Silvano Fasolato, Giacomo Zanus, Umberto Cillo, Angelo Gatta, Maurizio Parola, Patrizia Pontisso. SerpinB3 and Yap Interplay Increases Myc Oncogenic Activity. Scientific Reports 2015; 5(1) doi: 10.1038/srep17701
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Massimiliano Berretta, Carla Cavaliere, Lara Alessandrini, Brigida Stanzione, Gaetano Facchini, Luca Balestreri, Tiziana Perin, Vincenzo Canzonieri. Serum and tissue markers in hepatocellular carcinoma and cholangiocarcinoma: clinical and prognostic implications. Oncotarget 2017; 8(8): 14192 doi: 10.18632/oncotarget.13929
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Edoardo Abeni, Alessandro Salvi, Eleonora Marchina, Michele Traversa, Bruna Arici, Giuseppina De Petro. Sorafenib induces variations of the DNA methylome in HA22T/VGH human hepatocellular carcinoma-derived cells. International Journal of Oncology 2017; 51(1): 128 doi: 10.3892/ijo.2017.4019
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78 |
Jing Liu, Qing Zhang, Hang Chen, Zhihui Gao, Yao Li, Zhongyuan Sun, Rong Xiang, Sihe Zhang. Phage display library selection of a hypoxia-binding scFv antibody for liver cancer metabolic marker discovery. Oncotarget 2016; 7(25): 38105 doi: 10.18632/oncotarget.9460
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79 |
M. V. Novikova, N. V. Khromova, P. B. Kopnin. Components of the hepatocellular carcinoma microenvironment and their role in tumor progression. Biochemistry (Moscow) 2017; 82(8): 861 doi: 10.1134/S0006297917080016
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Carolina Méndez-Blanco, Paula Fernández-Palanca, Flavia Fondevila, Javier González-Gallego, José L. Mauriz. Prognostic and clinicopathological significance of hypoxia-inducible factors 1α and 2α in hepatocellular carcinoma: a systematic review with meta-analysis. Therapeutic Advances in Medical Oncology 2021; 13 doi: 10.1177/1758835920987071
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Zhizhong Li, Jeremy N. Rich. Diverse Effects of Hypoxia on Tumor Progression. Current Topics in Microbiology and Immunology 2010; 345: 21 doi: 10.1007/82_2010_75
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82 |
Sergio Rey, Luana Schito, Marianne Koritzinsky, Bradly G. Wouters. Molecular targeting of hypoxia in radiotherapy. Advanced Drug Delivery Reviews 2017; 109: 45 doi: 10.1016/j.addr.2016.10.002
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83 |
Xiaotian Dong, Xiaoru Su, Jiong Yu, Jingqi Liu, Xiaowei Shi, Qiaoling Pan, Jinfeng Yang, Jiajia Chen, Lanjuan Li, Hongcui Cao. Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex. Journal of Molecular Graphics and Modelling 2017; 71: 116 doi: 10.1016/j.jmgm.2016.11.011
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84 |
Zi‐Niu Ding, Zhao‐Ru Dong, Zhi‐Qiang Chen, Ya‐Fei Yang, Lun‐Jie Yan, Hai‐Chao Li, Kai‐Xuan Liu, Cheng‐Yu Yao, Yu‐Chuan Yan, Chun‐Cheng Yang, Tao Li. Effects of hypoxia‐inducible factor‐1α and hypoxia‐inducible factor‐2α overexpression on hepatocellular carcinoma survival: A systematic review with meta‐analysis. Journal of Gastroenterology and Hepatology 2021; 36(6): 1487 doi: 10.1111/jgh.15395
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85 |
Yan Qiao, Bin Wang, Huimin Zhang, Yu Yan, Ligang Niu. Retracted Article: FOXO4 overexpression suppresses hypoxia-induced-MCF-7 cell survival and promotes apoptosis through the HIF-2α/Bnip3 signal pathway. RSC Advances 2019; 9(44): 25912 doi: 10.1039/C9RA04380B
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