| For: | Lin JP, Yang JS, Lee JH, Hsieh WT, Chung JG. Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line. World J Gastroenterol 2006; 12(1): 21-28 [PMID: 16440412 DOI: 10.3748/wjg.v12.i1.21] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v12/i1/21.htm |
| Number | Citing Articles |
| 1 |
Wuli Zhao, Hong Liu, Junxia Wang, Mengyan Wang, Rongguang Shao. Cyclizing-berberine A35 induces G2/M arrest and apoptosis by activating YAP phosphorylation (Ser127). Journal of Experimental & Clinical Cancer Research 2018; 37(1) doi: 10.1186/s13046-018-0759-6
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| 2 |
Sayanta Dutta, Sushweta Mahalanobish, Sukanya Saha, Shatadal Ghosh, Parames C. Sil. Natural products: An upcoming therapeutic approach to cancer. Food and Chemical Toxicology 2019; 128 doi: 10.1016/j.fct.2019.04.012
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| 3 |
Takaaki Sugimoto, Yoko Kato, Yukio Tsunoda. The Effect of Berberine Treatment on the Reversibility of the Development of Mouse Zygotes and Gametes, and on the Fertilization and Subsequent Development. Journal of Mammalian Ova Research 2012; 29(1) doi: 10.1274/jmor.29.75
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| 4 |
Li-Na Lv, Xiao-Chao Wang, Li-Ju Tao, Hong-Wen Li, Shu-You Li, Fei-Meng Zheng. β-Asarone increases doxorubicin sensitivity by suppressing NF-κB signaling and abolishes doxorubicin-induced enrichment of stem-like population by destabilizing Bmi1. Cancer Cell International 2019; 19(1) doi: 10.1186/s12935-019-0873-3
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| 5 |
Myung-Ja Youn, Hong-Seob So, Hea-Joong Cho, Hyung-Jin Kim, Yunha Kim, Jeong-Han Lee, Jung Sook Sohn, Yong Kyu Kim, Sang-Young Chung, Raekil Park. Berberine, a Natural Product, Combined with Cisplatin Enhanced Apoptosis through a Mitochondria/Caspase-Mediated Pathway in HeLa Cells. Biological and Pharmaceutical Bulletin 2008; 31(5) doi: 10.1248/bpb.31.789
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| 6 |
Donghan Xu, Ziqing Lin, Lu Deng, Xiaonan Lu, Ziyi Guo, Peiyu Yan, Yehao Luo. Banxia xiexin decoction and its bioactive metabolites: multi-targeted mechanisms for suppressing gastric cancer progression, reversing chemoresistance, and remodeling the tumor microenvironment. Frontiers in Pharmacology 2026; 17 doi: 10.3389/fphar.2026.1810848
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| 7 |
Inês A. Barbosa, Nuno G. Machado, Andrew J. Skildum, Patricia M. Scott, Paulo J. Oliveira. Mitochondrial remodeling in cancer metabolism and survival: Potential for new therapies. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2012; 1826(1) doi: 10.1016/j.bbcan.2012.04.005
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| 8 |
Stephanie C. Casey, Amedeo Amedei, Katia Aquilano, Asfar S. Azmi, Fabian Benencia, Dipita Bhakta, Alan E. Bilsland, Chandra S. Boosani, Sophie Chen, Maria Rosa Ciriolo, Sarah Crawford, Hiromasa Fujii, Alexandros G. Georgakilas, Gunjan Guha, Dorota Halicka, William G. Helferich, Petr Heneberg, Kanya Honoki, W. Nicol Keith, Sid P. Kerkar, Sulma I. Mohammed, Elena Niccolai, Somaira Nowsheen, H.P. Vasantha Rupasinghe, Abbas Samadi, Neetu Singh, Wamidh H. Talib, Vasundara Venkateswaran, Richard L. Whelan, Xujuan Yang, Dean W. Felsher. Cancer prevention and therapy through the modulation of the tumor microenvironment. Seminars in Cancer Biology 2015; 35 doi: 10.1016/j.semcancer.2015.02.007
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| 9 |
Xiaoqin La, Lichao Zhang, Zhuoyu Li, Peng Yang, Yingying Wang. Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells. Oncotarget 2017; 8(13) doi: 10.18632/oncotarget.14959
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| 10 |
J.B. Kim, J.-H. Yu, E. Ko, K.-W. Lee, A.K. Song, S.Y. Park, I. Shin, W. Han, D.Y. Noh. The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest. Phytomedicine 2010; 17(6) doi: 10.1016/j.phymed.2009.08.012
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| 11 |
Bokyung Sung, Sahdeo Prasad, Subash C. Gupta, Sridevi Patchva, Bharat B. Aggarwal. Recent Trends in Medicinal Plants Research. Advances in Botanical Research 2012; 62 doi: 10.1016/B978-0-12-394591-4.00003-9
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| 12 |
Wuli Zhao, Guohua Jiang, Chongwen Bi, Yangbiao Li, Jingbo Liu, Cheng Ye, Hongwei He, Liang Li, Danqing Song, Rongguang Shao. The dual topoisomerase inhibitor A35 preferentially and specially targets topoisomerase 2α by enhancing pre-strand and post-strand cleavage and inhibiting DNA religation. Oncotarget 2015; 6(35) doi: 10.18632/oncotarget.5680
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| 13 |
AmirReza Hesari, Faezeh Ghasemi, Arrigo F. G. Cicero, Mohammad Mohajeri, Omid Rezaei, Seyed Mohammad Gheibi Hayat, Amirhossein Sahebkar. Berberine: A potential adjunct for the treatment of gastrointestinal cancers?. Journal of Cellular Biochemistry 2018; 119(12) doi: 10.1002/jcb.27392
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| 14 |
Elena von Coburg, Marlene Wedler, Jose M. Muino, Christopher Wolff, Nils Körber, Sebastian Dunst, Shu Liu. Cell Painting PLUS: expanding the multiplexing capacity of Cell Painting-based phenotypic profiling using iterative staining-elution cycles. Nature Communications 2025; 16(1) doi: 10.1038/s41467-025-58765-8
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| 15 |
Qiao Liu, Haiyan Jiang, Zhaojian Liu, Yu Wang, Minnan Zhao, Chunyan Hao, Shuai Feng, Haiyang Guo, Bing Xu, Qifeng Yang, Yaoqin Gong, Changshun Shao, Qian Tao. Berberine Radiosensitizes Human Esophageal Cancer Cells by Downregulating Homologous Recombination Repair Protein RAD51. PLoS ONE 2011; 6(8) doi: 10.1371/journal.pone.0023427
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| 16 |
Mee‐Sun Hyun, Jung‐Mu Hur, Yeun‐Ja Mun, Dongho Kim, Won‐Hong Woo. BBR induces apoptosis in HepG2 cell through an Akt‐ASK1‐ROS‐p38MAPKs‐linked cascade. Journal of Cellular Biochemistry 2010; 109(2) doi: 10.1002/jcb.22384
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| 17 |
Sutapa Mahata, Alok C Bharti, Shirish Shukla, Abhishek Tyagi, Syed A Husain, Bhudev C Das. Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells. Molecular Cancer 2011; 10(1) doi: 10.1186/1476-4598-10-39
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| 18 |
Amirhossein Davoodvandi, Sahand Sadeghi, Seyed Mohammad Amin Alavi, Seyedeh Shaghayegh Alavi, Ameneh Jafari, Haroon Khan, Michael Aschner, Hamed Mirzaei, Mehran Sharifi, Zatollah Asemi. The therapeutic effects of berberine for gastrointestinal cancers. Asia-Pacific Journal of Clinical Oncology 2024; 20(2) doi: 10.1111/ajco.13941
|
| 19 |
Christophe Wiart. Lead Compounds from Medicinal Plants for the Treatment of Cancer. 2013; doi: 10.1016/B978-0-12-398371-8.00001-5
|
| 20 |
Xiu-Zhen Zhang, Ling Wang, Dong-Wu Liu, Guang-Yan Tang, Hong-Yu Zhang.
Synergistic Inhibitory Effect of Berberine and
d
-Limonene on Human Gastric Carcinoma Cell Line MGC803
. Journal of Medicinal Food 2014; 17(9) doi: 10.1089/jmf.2013.2967
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| 21 |
Wenhua Gao, Jinjin Wang, Jia Zhao. Describing a modern chemotherapeutic drug prepared by Au nanoparticles to treat the human oral squamous cell carcinoma: A pre-clinical trial study. Inorganic Chemistry Communications 2022; 136 doi: 10.1016/j.inoche.2021.109138
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| 22 |
Zatollah Asemi, Mohammad Behnam, Mohammad Ali Pourattar, Hamed Mirzaei, Zahra Sadat Razavi, Omid Reza Tamtaji. Therapeutic Potential of Berberine in the Treatment of Glioma: Insights into Its Regulatory Mechanisms. Cellular and Molecular Neurobiology 2021; 41(6) doi: 10.1007/s10571-020-00903-5
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| 23 |
Rojsanga Piyanuch, Mugdha Sukhthankar, Gritsanapan Wandee, Seung Joon Baek. Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF3 expression in human colorectal cancer cells. Cancer Letters 2007; 258(2) doi: 10.1016/j.canlet.2007.09.007
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| 24 |
Chao Wang, Huan Wang, Yaqian Zhang, Wei Guo, Cong Long, Jingchao Wang, Limei Liu, Xiaoping Sun. Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism. Oncology Reports 2017; 37(4) doi: 10.3892/or.2017.5489
|
| 25 |
Ana Burgeiro, Consuelo Gajate, EL Habib Dakir, Janny A. Villa-Pulgarín, Paulo J. Oliveira, Faustino Mollinedo. Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells. Anti-Cancer Drugs 2011; 22(6) doi: 10.1097/CAD.0b013e32834438f6
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| 26 |
Sabyasachi Chatterjee, Sumana Mallick, Franco Buzzetti, Gaetano Fiorillo, Tanjia Monir Syeda, Paolo Lombardi, Krishna Das Saha, Gopinatha Suresh Kumar. New 13-pyridinealkyl berberine analogues intercalate to DNA and induce apoptosis in HepG2 and MCF-7 cells through ROS mediated p53 dependent pathway: biophysical, biochemical and molecular modeling studies. RSC Advances 2015; 5(110) doi: 10.1039/C5RA17214D
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| 27 |
Santu Kumar Saha, Anisur Rahman Khuda-Bukhsh. Molecular approaches towards development of purified natural products and their structurally known derivatives as efficient anti-cancer drugs: Current trends. European Journal of Pharmacology 2013; 714(1-3) doi: 10.1016/j.ejphar.2013.06.009
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| 28 |
Ammara Riaz, Azhar Rasul, Rabia Batool, Lubna Kanwal, Ghulam Hussain, Iqra Sarfraz, Muhammad Ajmal Shah, Faiza Rao, Ilknur Ucak, Sevki Adem, Marwa A.A. Fayed. Phytonutrients in the Treatment of Gastrointestinal Cancer. 2023; doi: 10.2174/9789815049633123010011
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| 29 |
Soumitra Hazra, Maidul Hossain, Gopinatha Suresh Kumar. Studies on α-, β-, and γ-cyclodextrin inclusion complexes of isoquinoline alkaloids berberine, palmatine and coralyne. Journal of Inclusion Phenomena and Macrocyclic Chemistry 2014; 78(1-4) doi: 10.1007/s10847-013-0301-6
|
| 30 |
Yaghub Pazhang, Shahin Ahmadian, Nader Javadifar, Mahshid Shafiezadeh. COX-2 and survivin reduction may play a role in berberine-induced apoptosis in human ductal breast epithelial tumor cell line. Tumor Biology 2012; 33(1) doi: 10.1007/s13277-011-0263-5
|
| 31 |
Hiroki Goto, Ryusho Kariya, Masako Shimamoto, Eriko Kudo, Manabu Taura, Harutaka Katano, Seiji Okada. Antitumor effect of berberine against primary effusion lymphoma via inhibition of NF‐κB pathway. Cancer Science 2012; 103(4) doi: 10.1111/j.1349-7006.2012.02212.x
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| 32 |
Che-Yi Lin, Pei-Ling Hsieh, Yi-Wen Liao, Chih-Yu Peng, Ming-Yi Lu, Ching-Hsuan Yang, Cheng-Chia Yu, Chia-Ming Liu. Berberine-targeted miR-21 chemosensitizes oral carcinomas stem cells. Oncotarget 2017; 8(46) doi: 10.18632/oncotarget.20723
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| 33 |
Poorna Chandra Rao, Sajeli Begum, Mahendra Sahai, D Saketh Sriram. Coptisine-induced cell cycle arrest at G2/M phase and reactive oxygen species–dependent mitochondria-mediated apoptosis in non-small-cell lung cancer A549 cells. Tumor Biology 2017; 39(3) doi: 10.1177/1010428317694565
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| 34 |
Xuanxuan Cheng, Dongmei Wang, Lin Jiang, Depo Yang. DNA Topoisomerase I Inhibitory Alkaloids from Corydalis saxicola. Chemistry & Biodiversity 2008; 5(7) doi: 10.1002/cbdv.200890121
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| 35 |
Parham Jabbarzadeh Kaboli, Asmah Rahmat, Patimah Ismail, King-Hwa Ling. Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. European Journal of Pharmacology 2014; 740 doi: 10.1016/j.ejphar.2014.06.025
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| 36 |
Bahram Bibak, Farzaneh Shakeri, Zakieh Keshavarzi, Hamid Mollazadeh, Hossein Javid, Mohammad Jalili-Nik, Thozhukat Sathyapalan, Amir R. Afshari, Amirhossein Sahebkar. Anticancer Mechanisms of Berberine: A Good Choice for Glioblastoma
Multiforme Therapy. Current Medicinal Chemistry 2022; 29(26) doi: 10.2174/0929867329666220224112811
|
| 37 |
XIAOJUAN HU, XIAOHUA WU, YUNFEI HUANG, QINGYI TONG, SHUNICHI TAKEDA, YONG QING. Berberine induces double-strand DNA breaks in Rev3 deficient cells. Molecular Medicine Reports 2014; 9(5) doi: 10.3892/mmr.2014.1999
|
| 38 |
Teresa L. Serafim, Paulo J. Oliveira, Vilma A. Sardao, Ed Perkins, Donna Parke, Jon Holy. Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line. Cancer Chemotherapy and Pharmacology 2008; 61(6) doi: 10.1007/s00280-007-0558-9
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| 39 |
Pei-ling Peng, Wu-Hsien Kuo, Hsien-Chun Tseng, Fen-Pi Chou. Synergistic Tumor-Killing Effect of Radiation and Berberine Combined Treatment in Lung Cancer: The Contribution of Autophagic Cell Death. International Journal of Radiation Oncology*Biology*Physics 2008; 70(2) doi: 10.1016/j.ijrobp.2007.08.034
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| 40 |
Xuanxuan Cheng, Dongmei Wang, Lin Jiang, Depo Yang. Simultaneous determination of eight bioactive alkaloids in Corydalis saxicola by high‐performance liquid chromatography coupled with diode array detection. Phytochemical Analysis 2008; 19(5) doi: 10.1002/pca.1067
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| 41 |
Minha Naseer, Rana Ramadan, Jianmin Xing, Nadia A. Samak. Facile green synthesis of copper oxide nanoparticles for the eradication of multidrug resistant Klebsiella pneumonia and Helicobacter pylori biofilms. International Biodeterioration & Biodegradation 2021; 159 doi: 10.1016/j.ibiod.2021.105201
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| 42 |
Xiu-hua Wang, Song-min Jiang, Qing-wen Sun. Effects of berberine on human rheumatoid arthritis fibroblast-like synoviocytes. Experimental Biology and Medicine 2011; 236(7) doi: 10.1258/ebm.2011.010366
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| 43 |
Nattapong Puthdee, Wunchana Seubwai, Kulthida Vaeteewoottacharn, Thidarut Boonmars, Ubon Cha’on, Chatchai Phoomak, Sopit Wongkham. Berberine Induces Cell Cycle Arrest in Cholangiocarcinoma Cell Lines <i>via</i> Inhibition of NF-κB and STAT3 Pathways. Biological & Pharmaceutical Bulletin 2017; 40(6) doi: 10.1248/bpb.b16-00428
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| 44 |
Marco Calvaruso, Gaia Pucci, Rosa Musso, Valentina Bravatà, Francesco P. Cammarata, Giorgio Russo, Giusi I. Forte, Luigi Minafra. Nutraceutical Compounds as Sensitizers for Cancer Treatment in Radiation Therapy. International Journal of Molecular Sciences 2019; 20(21) doi: 10.3390/ijms20215267
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| 45 |
Munira Khatun, Gopal Chandra Jana, Sk Nayim, Asima Dhal, Anirudha Patra, Maidul Hossain. Evaluation of the size effect of hydrophobic ring substitution on 9-O position of berberine on DNA binding. Journal of Biomolecular Structure and Dynamics 2023; 41(23) doi: 10.1080/07391102.2023.2180436
|
| 46 |
GAETANO MARVERTI, ALESSIO LIGABUE, PAOLO LOMBARDI, STEFANIA FERRARI, MARIA GIUSEPPINA MONTI, CHIARA FRASSINETI, MARIA PAOLA COSTI. Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells. International Journal of Oncology 2013; 43(4) doi: 10.3892/ijo.2013.2045
|
| 47 |
Hong-Jhih Lin, Jinn-Hsuan Ho, Li-Chen Tsai, Fang-Yu Yang, Ling-Ling Yang, Cheng-Deng Kuo, Lih-Geeng Chen, Yi-Wen Liu, Jin-Yi Wu. Synthesis and In Vitro Photocytotoxicity of 9-/13-Lipophilic Substituted Berberine Derivatives as Potential Anticancer Agents. Molecules 2020; 25(3) doi: 10.3390/molecules25030677
|
| 48 |
Shatrunajay Shukla, Fatima Rizvi, Sheikh Raisuddin, Poonam Kakkar. FoxO proteins’ nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells. Free Radical Biology and Medicine 2014; 76 doi: 10.1016/j.freeradbiomed.2014.07.039
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| 49 |
Debipreeta Bhowmik, Maidul Hossain, Franco Buzzetti, Rosaria D’Auria, Paolo Lombardi, Gopinatha Suresh Kumar. Biophysical Studies on the Effect of the 13 Position Substitution of the Anticancer Alkaloid Berberine on Its DNA Binding. The Journal of Physical Chemistry B 2012; 116(7) doi: 10.1021/jp210072a
|
| 50 |
Cai-Hong Li, Dong-Fang Wu, Hang Ding, Yang Zhao, Ke-Yuan Zhou, De-Feng Xu. Berberine Hydrochloride Impact on Physiological Processes and Modulation of Twist Levels in Nasopharyngeal Carcinoma CNE-1 Cells. Asian Pacific Journal of Cancer Prevention 2014; 15(4) doi: 10.7314/APJCP.2014.15.4.1851
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| 51 |
Ki-Seong Eom, Ji-Myoung Hong, Myung-Ja Youn, Hong-Seob So, Raekil Park, Jong-Moon Kim, Tae-Young Kim. Berberine Induces G1 Arrest and Apoptosis in Human Glioblastoma T98G Cells through Mitochondrial/Caspases Pathway. Biological and Pharmaceutical Bulletin 2008; 31(4) doi: 10.1248/bpb.31.558
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| 52 |
Sabyasachi Chatterjee, Gopinatha Suresh Kumar. Visualization of Stepwise Drug–Micelle Aggregate Formation and Correlation with Spectroscopic and Calorimetric Results. The Journal of Physical Chemistry B 2016; 120(45) doi: 10.1021/acs.jpcb.6b06839
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| 53 |
Yaghub Pazhang, Shahin Ahmadian, Massoud Mahmoudian, Mahshid Shafiezadeh. Berberine-induced apoptosis via decreasing the survivin protein in K562 cell line. Medical Oncology 2011; 28(4) doi: 10.1007/s12032-010-9586-0
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| 54 |
Chandrima Jash, Gopinatha Suresh Kumar. Binding of alkaloids berberine, palmatine and coralyne to lysozyme: a combined structural and thermodynamic study. RSC Advances 2014; 4(24) doi: 10.1039/c3ra46053c
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| 55 |
Yingmei Wang, Ping Ji, Jinsong Liu, Russell R Broaddus, Fengxia Xue, Wei Zhang. Centrosome-associated regulators of the G2/M checkpoint as targets for cancer therapy. Molecular Cancer 2009; 8(1) doi: 10.1186/1476-4598-8-8
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| 56 |
Wei He, Bin Wang, Yun Zhuang, Dong Shao, Kewen Sun, Jianping Chen. Berberine Inhibits Growth and Induces G1 Arrest and Apoptosis in Human Cholangiocarcinoma QBC939 Cells. Journal of Pharmacological Sciences 2012; 119(4) doi: 10.1254/jphs.12052FP
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| 57 |
Gonçalo C. Pereira, Ana F. Branco, Júlio A.C. Matos, Sandro L. Pereira, Donna Parke, Edward L. Perkins, Teresa L. Serafim, Vilma A. Sardão, Maria S. Santos, Antonio J.M. Moreno, Jon Holy, Paulo J. Oliveira. Mitochondrially Targeted Effects of Berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 Mouse Melanoma Cells: Comparison with Direct Effects on Isolated Mitochondrial Fractions. The Journal of Pharmacology and Experimental Therapeutics 2007; 323(2) doi: 10.1124/jpet.107.128017
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| 58 |
Ali A. Alshatwi, P. Subash-Babu, P. Antonisamy. Violacein induces apoptosis in human breast cancer cells through up regulation of BAX, p53 and down regulation of MDM2. Experimental and Toxicologic Pathology 2016; 68(1) doi: 10.1016/j.etp.2015.10.002
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| 59 |
Jülide Secerli, Şeyma Adatepe, Sevde Altuntas, Gizem Rüya Topal, Onur Erdem, Merve Bacanlı. In vitro toxicity of naringin and berberine alone, and encapsulated within PMMA nanoparticles. Toxicology in Vitro 2023; 89 doi: 10.1016/j.tiv.2023.105580
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| 60 |
Rokeya Akter, Agnieszka Najda, Md. Rahman, Muddaser Shah, Sylwia Wesołowska, Syed Hassan, Sidra Mubin, Parveen Bibi, Saeeda Saeeda. RETRACTED: Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives. Molecules 2021; 26(19) doi: 10.3390/molecules26195997
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| 61 |
KEFENG WU, YI LIU, YINGNIAN LV, LIAO CUI, WENDE LI, JIANFA CHEN, NIAN CI LIANG, LI LI. Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis and cell cycle arrest in CNE-2Z nasopharyngeal carcinoma cells. Oncology Reports 2013; 29(6) doi: 10.3892/or.2013.2375
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| 62 |
Qingsong Liu, Jianyuan Tang, Shuanglan Chen, Shuangyuan Hu, Caifei Shen, Juyi Xiang, Nianzhi Chen, Jundong Wang, Xiao Ma, Yi Zhang, Jinhao Zeng. Berberine for gastric cancer prevention and treatment: Multi-step actions on the Correa’s cascade underlie its therapeutic effects. Pharmacological Research 2022; 184 doi: 10.1016/j.phrs.2022.106440
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| 63 |
Musa Khan, Benedikt Giessrigl, Caroline Vonach, Sibylle Madlener, Sonja Prinz, Irene Herbaceck, Christine Hölzl, Sabine Bauer, Katharina Viola, Wolfgang Mikulits, Rizwana Aleem Quereshi, Siegfried Knasmüller, Michael Grusch, Brigitte Kopp, Georg Krupitza. Berberine and a Berberis lycium extract inactivate Cdc25A and induce α-tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 2010; 683(1-2) doi: 10.1016/j.mrfmmm.2009.11.001
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| 64 |
He-Yi You, Xue-Meng Xie, Wei-Jian Zhang, Heng-Liang Zhu, Fei-Zhao Jiang. Berberine modulates cisplatin sensitivity of human gastric cancer cells by upregulation of miR-203. In Vitro Cellular & Developmental Biology - Animal 2016; 52(8) doi: 10.1007/s11626-016-0044-y
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| 65 |
In silico anticancer targets of L-menthol. International Journal of Biosciences (IJB) 2019; doi: 10.12692/ijb/15.4.248-253
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| 66 |
Yu Wang, Qiao Liu, Zhaojian Liu, Boxuan Li, Zhaoliang Sun, Haibin Zhou, Xiyu Zhang, Yaoqin Gong, Changshun Shao. Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 2012; 734(1-2) doi: 10.1016/j.mrfmmm.2012.04.005
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| 67 |
Jung‐Mu Hur, Mee‐Sun Hyun, Sang‐Yong Lim, Woo‐Yiel Lee, Dongho Kim. The combination of berberine and irradiation enhances anti‐cancer effects via activation of p38 MAPK pathway and ROS generation in human hepatoma cells. Journal of Cellular Biochemistry 2009; 107(5) doi: 10.1002/jcb.22198
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| 68 |
Marina Raju, Yogesh A. Kulkarni, Sarika Wairkar. Therapeutic potential and recent delivery systems of berberine: A wonder molecule. Journal of Functional Foods 2019; 61 doi: 10.1016/j.jff.2019.103517
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| 69 |
Tanmoy Bhowmik, Partha Pratim Saha, Amrita Sarkar, Antony Gomes. Evaluation of cytotoxicity of a purified venom protein from Naja kaouthia (NKCT1) using gold nanoparticles for targeted delivery to cancer cell. Chemico-Biological Interactions 2017; 261 doi: 10.1016/j.cbi.2016.11.007
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| 70 |
Tanmoy Bhowmik, Partha Pratim Saha, Anjan Dasgupta, Antony Gomes. Antileukemic potential of PEGylated gold nanoparticle conjugated with protein toxin (NKCT1) isolated from Indian cobra (Naja kaouthia) venom. Cancer Nanotechnology 2013; 4(1-3) doi: 10.1007/s12645-013-0036-5
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| 71 |
Bing-Sang Wong, Yung-Chin Hsiao, Ta-Wei Lin, Kuo-Shuen Chen, Pei-Ni Chen, Wu-Hsien Kuo, Shu-Chen Chu, Yih-Shou Hsieh. The in vitro and in vivo apoptotic effects of Mahonia oiwakensis on human lung cancer cells. Chemico-Biological Interactions 2009; 180(2) doi: 10.1016/j.cbi.2009.02.011
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| 72 |
Hong-Li Li, Hui Wu, Bei-Bei Zhang, Hai-Lian Shi, Xiao-Jun Wu. MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo. Molecular Medicine Reports 2016; 14(2) doi: 10.3892/mmr.2016.5361
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| 73 |
Daipeng Xiao, Fen He, Dongming Peng, Min Zou, Junying Peng, Pan Liu, Yanfei Liu, Zhenbao Liu. Synthesis and Anticancer Activity of 9-O-Pyrazole Alkyl Substituted Berberine Derivatives. Anti-Cancer Agents in Medicinal Chemistry 2019; 18(11) doi: 10.2174/1871520618666180717121208
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| 74 |
Yingying Kou, Bending Tong, Weiqing Wu, Xiangqing Liao, Min Zhao. Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer. Frontiers in Pharmacology 2020; 11 doi: 10.3389/fphar.2020.616251
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| 75 |
Abdullah Faisal Albukhari. Berberine and its structural diversity: structure–activity relationships, molecular mechanisms, and drug discovery opportunities. Molecular Biology Reports 2026; 53(1) doi: 10.1007/s11033-026-11967-9
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| 76 |
Yanyuan Zhou, Tungyi Lin, Tingan Chiang, Peiming Yang, Tailong Pan. The Role of Traditional Chinese Medicine in the Management of Polyploid Giant Cancer Cells. The American Journal of Chinese Medicine 2026; 54(02) doi: 10.1142/S0192415X26500175
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| 77 |
Yuchen Cai, Qing Xia, Rongzhen Luo, Peiyu Huang, Yueli Sun, Yanxia Shi, Wenqi Jiang. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. Journal of Natural Medicines 2014; 68(1) doi: 10.1007/s11418-013-0766-z
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| 78 |
Xuanbin Wang, Ning Wang, Hongliang Li, Ming Liu, Fengjun Cao, Xianjun Yu, Jingxuan Zhang, Yan Tan, Longchao Xiang, Yibin Feng. Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. International Journal of Molecular Sciences 2016; 17(4) doi: 10.3390/ijms17040577
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