For: | Lo YC, Yang YC, Wu IC, Kuo FC, Liu CM, Wang HW, Kuo CH, Wu JY, Wu DC. Capsaicin-induced cell death in a human gastric adenocarcinoma cell line. World J Gastroenterol 2005; 11(40): 6254-6257 [PMID: 16419151 DOI: 10.3748/wjg.v11.i40.6254] |
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URL: | https://www.wjgnet.com/1007-9327/full/v11/i40/6254.htm |
Number | Citing Articles |
1 |
David G. Popovich, Sharon Y. Sia, Wei Zhang, Mon L. Lim. The color and size of chili peppers (Capsicum annuum) influence Hep-G2 cell growth. International Journal of Food Sciences and Nutrition 2014; 65(7): 881 doi: 10.3109/09637486.2014.931358
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2 |
Hsi‐Ming Wang, Pin Ju Chueh, Sheng‐Pang Chang, Chi‐Lien Yang, Kuo‐Ning Shao. Effect of Ccapsaicin on tNOX (ENOX2) protein expression in stomach cancer cells. BioFactors 2008; 34(3): 209 doi: 10.1002/biof.5520340305
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3 |
Margherita Lavorgna, Elena Orlo, Roberta Nugnes, Concetta Piscitelli, Chiara Russo, Marina Isidori. Capsaicin in Hot Chili Peppers: In Vitro Evaluation of Its Antiradical, Antiproliferative and Apoptotic Activities. Plant Foods for Human Nutrition 2019; 74(2): 164 doi: 10.1007/s11130-019-00722-0
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4 |
Justine Chow, Manith Norng, Jing Zhang, Jianyuan Chai. TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells—Mechanisms behind a possible new “hot” cancer treatment. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2007; 1773(4): 565 doi: 10.1016/j.bbamcr.2007.01.001
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5 |
Amal K. Maji, Pratim Banerji. Phytochemistry and gastrointestinal benefits of the medicinal spice, Capsicum annuum L. (Chilli): a review. Journal of Complementary and Integrative Medicine 2016; 13(2): 97 doi: 10.1515/jcim-2015-0037
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6 |
Francisco Luján-Méndez, Octavio Roldán-Padrón, J. Castro-Ruíz, Josué López-Martínez, Teresa García-Gasca. Capsaicinoids and Their Effects on Cancer: The “Double-Edged Sword” Postulate from the Molecular Scale. Cells 2023; 12(21): 2573 doi: 10.3390/cells12212573
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7 |
Kartick C. Pramanik, Srinivas Reddy Boreddy, Sanjay K. Srivastava, Michael Polymenis. Role of Mitochondrial Electron Transport Chain Complexes in Capsaicin Mediated Oxidative Stress Leading to Apoptosis in Pancreatic Cancer Cells. PLoS ONE 2011; 6(5): e20151 doi: 10.1371/journal.pone.0020151
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8 |
Shaherin Basith, Minghua Cui, Sunhye Hong, Sun Choi. Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases. Molecules 2016; 21(8): 966 doi: 10.3390/molecules21080966
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9 |
His-Ming Wang, Show-Mei Chuang, Yu-Ching Su, Yi-Hui Li, Pin Ju Chueh. Down-Regulation of Tumor-Associated NADH Oxidase, tNOX (ENOX2), Enhances Capsaicin-Induced Inhibition of Gastric Cancer Cell Growth. Cell Biochemistry and Biophysics 2011; 61(2): 355 doi: 10.1007/s12013-011-9218-0
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10 |
Pin Ju Chueh. Role of Capsaicin in Oxidative Stress and Cancer. 2013; : 131 doi: 10.1007/978-94-007-6317-3_7
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11 |
Elena Madalina Petran, Argyrios Periferakis, Lamprini Troumpata, Aristodemos-Theodoros Periferakis, Andreea-Elena Scheau, Ioana Anca Badarau, Konstantinos Periferakis, Ana Caruntu, Ilinca Savulescu-Fiedler, Romina-Marina Sima, Daniela Calina, Carolina Constantin, Monica Neagu, Constantin Caruntu, Cristian Scheau. Capsaicin: Emerging Pharmacological and Therapeutic Insights. Current Issues in Molecular Biology 2024; 46(8): 7895 doi: 10.3390/cimb46080468
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12 |
Jin Ho Jeon, Yoon Ji Choi, In Ho Han, Byung Kwan Choi, Seung Heon Cha, Won Ho Cho. Capsaicin-induced apoptosis in the human glioblastoma U87MG cells via p-38 MAPK and Bcl-2/Bax signaling pathway. Molecular & Cellular Toxicology 2012; 8(1): 69 doi: 10.1007/s13273-012-0009-5
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13 |
S. H. Lee, C. Krisanapun, S. J. Baek. NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3 , C/EBP and ATF3. Carcinogenesis 2010; 31(4): 719 doi: 10.1093/carcin/bgq016
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14 |
Sylvester R. Groen, Daniel Keszthelyi, Arpad Szallasi, Jara A. van Veghel, Annick M. E. Alleleyn, Kata Csekő, Zsuzsanna Helyes, Iryna Samarska, Heike I. Grabsch, Ad A. M. Masclee, Zsa Zsa R. M. Weerts. Gastric Carcinogenesis and Potential Role of the Transient Receptor Potential Vanilloid 1 (TRPV1) Receptor: An Observational Histopathological Study. International Journal of Molecular Sciences 2024; 25(15): 8294 doi: 10.3390/ijms25158294
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15 |
Aihua Peng, Haoyu Ye, Xia Li, Lijuan Chen. Preparative separation of capsaicin and dihydrocapsaicin from Capsicum frutescens by high‐speed counter‐current chromatography. Journal of Separation Science 2009; 32(17): 2967 doi: 10.1002/jssc.200900151
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16 |
Bahare Salehi, Alan Javier Hernández-Álvarez, María del Mar Contreras, Miquel Martorell, Karina Ramírez-Alarcón, Guiomar Melgar-Lalanne, Karl R. Matthews, Mehdi Sharifi-Rad, William N. Setzer, Muhammad Nadeem, Zubaida Yousaf, Javad Sharifi-Rad. Potential Phytopharmacy and Food Applications of Capsicum spp.: A Comprehensive Review. Natural Product Communications 2018; 13(11) doi: 10.1177/1934578X1801301133
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17 |
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18 |
Peticha Tanprasert, Sirikan Limpakan, Siriporn C. Chattipakorn, Nipon Chattipakorn, Krekwit Shinlapawittayatorn. Targeting mitochondria as a therapeutic anti-gastric cancer approach. Apoptosis 2022; 27(3-4): 163 doi: 10.1007/s10495-022-01709-0
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19 |
Zahira Fernández-Bedmar, Angeles Alonso-Moraga. In vivo and in vitro evaluation for nutraceutical purposes of capsaicin, capsanthin, lutein and four pepper varieties. Food and Chemical Toxicology 2016; 98: 89 doi: 10.1016/j.fct.2016.10.011
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20 |
Hai-Ning YU, Zun-Chen WANG, Sheng-Rong SHEN, Wei-Guang SHAN. Effects of Capsaicin and Its Analogs on the Growth of Gastric Cancer Cells and Their Structure-activity Relationships In Vitro. Food Science and Technology Research 2013; 19(5): 865 doi: 10.3136/fstr.19.865
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21 |
Jyh-Cheng Chen, Jen-Chung Ko, Ting-Chuan Yen, Tzu-Ying Chen, Yuan-Cheng Lin, Peng-Fang Ma, Yun-Wei Lin. Capsaicin enhances erlotinib-induced cytotoxicity via AKT inactivation and excision repair cross-complementary 1 (ERCC1) down-regulation in human lung cancer cells. Toxicology Research 2019; 8(3): 459 doi: 10.1039/C8TX00346G
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22 |
P. Anandakumar, S. Kamaraj, S. Jagan, G. Ramakrishnan, T. Devaki. Capsaicin provokes apoptosis and restricts benzo(a)pyrene induced lung tumorigenesis in Swiss albino mice. International Immunopharmacology 2013; 17(2): 254 doi: 10.1016/j.intimp.2013.05.015
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23 |
Gaber El-Saber Batiha, Ali Alqahtani, Oluwafemi Adeleke Ojo, Hazem M. Shaheen, Lamiaa Wasef, Mahmoud Elzeiny, Mahmoud Ismail, Mahmoud Shalaby, Toshihiro Murata, Adrian Zaragoza-Bastida, Nallely Rivero-Perez, Amany Magdy Beshbishy, Keneth Iceland Kasozi, Philippe Jeandet, Helal F. Hetta. Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids. International Journal of Molecular Sciences 2020; 21(15): 5179 doi: 10.3390/ijms21155179
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24 |
Young-Joon Surh, Joydeb Kumar Kundu. Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention. 2011; : 123 doi: 10.1007/978-90-481-9800-9_6
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25 |
SEON-YOUNG PARK, JI-YOUNG KIM, SU-MI LEE, CHUNG-HWAN JUN, SUNG-BUM CHO, CHANG-HWAN PARK, YOUNG-EUN JOO, HYUN-SOO KIM, SUNG-KYU CHOI, JONG-SUN REW. Capsaicin induces apoptosis and modulates MAPK signaling in human gastric cancer cells. Molecular Medicine Reports 2014; 9(2): 499 doi: 10.3892/mmr.2013.1849
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26 |
Katherine Sattler, Ibrahim El-Battrawy, Lukas Cyganek, Siegfried Lang, Huan Lan, Xin Li, Zhihan Zhao, Jochen Utikal, Thomas Wieland, Martin Borggrefe, Xiaobo Zhou, Ibrahim Akin. TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes. Scientific Reports 2021; 11(1) doi: 10.1038/s41598-021-93958-3
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27 |
George Denis Alexandru Popescu, Cristian Scheau, Ioana Anca Badarau, Mihai-Daniel Dumitrache, Ana Caruntu, Andreea-Elena Scheau, Daniel Octavian Costache, Raluca Simona Costache, Carolina Constantin, Monica Neagu, Constantin Caruntu. The Effects of Capsaicin on Gastrointestinal Cancers. Molecules 2020; 26(1): 94 doi: 10.3390/molecules26010094
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28 |
Kartick C. Pramanik, Sanjay K. Srivastava. Role of Capsaicin in Oxidative Stress and Cancer. 2013; : 1 doi: 10.1007/978-94-007-6317-3_1
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29 |
Kalyani Saha, Deotima Sarkar, Uzma Khan, Bipul Chandra Karmakar, Sangita Paul, Asish K. Mukhopadhyay, Shanta Dutta, Sushmita Bhattacharya. Capsaicin Inhibits Inflammation and Gastric Damage during H pylori Infection by Targeting NF-kB–miRNA Axis. Pathogens 2022; 11(6): 641 doi: 10.3390/pathogens11060641
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30 |
Kartick C. Pramanik, Neel M. Fofaria, Parul Gupta, Alok Ranjan, Sung-Hoon Kim, Sanjay K. Srivastava. Inhibition of β-Catenin signaling suppresses pancreatic tumor growth by disrupting nuclear β-Catenin/TCF-1 complex: Critical role of STAT-3. Oncotarget 2015; 6(13): 11561 doi: 10.18632/oncotarget.3427
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31 |
Viktorija Maksimova, Liljana K. Gudeva, Rubin Gulaboski, Karen Nieber. Co-extracted bioactive compounds in Capsicum fruit extracts prevent the cytotoxic effects of capsaicin on B104 neuroblastoma cells. Revista Brasileira de Farmacognosia 2016; 26(6): 744 doi: 10.1016/j.bjp.2016.06.009
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32 |
Hsiao-Ling Cheng, Yi-Hui Lee, Tein-Ming Yuan, Shi-Wen Chen, Pin-Ju Chueh. Update on a tumor-associated NADH oxidase in gastric cancer cell growth. World Journal of Gastroenterology 2016; 22(10): 2900-2905 doi: 10.3748/wjg.v22.i10.2900
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33 |
Chun-Liang Tung, Jyh-Cheng Chen, Jen-Chung Ko, Li-Ling Liu, Chin-Cheng Chien, I-Hsiang Huang, Yong-Cing Tsao, Hsiang-Hung Cheng, Tzu-Ying Chen, Ting-Chuan Yen, Yun-Wei Lin. Capsaicin Acts Through Reducing P38 MAPK-Dependent Thymidylate Synthase Expression to Enhance 5-Fluorouracil-Induced Cytotoxicity in Human Lung Cancer Cells. Natural Product Communications 2021; 16(2) doi: 10.1177/1934578X21993335
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34 |
Ravindran Jaganathan, Boregowda Purushotham, Narayanaswamy Radhakrishnan, Mallappa Kumara Swamy. Plant-derived Bioactives. 2020; : 301 doi: 10.1007/978-981-15-2361-8_14
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35 |
Junlian Xing, Jihua Ma, Peihua Zhang, Xinrong Fan. Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652. European Journal of Pharmacology 2010; 630(1-3): 1 doi: 10.1016/j.ejphar.2009.11.009
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36 |
M. Skrzypski, M. Sassek, S. Abdelmessih, S. Mergler, C. Grötzinger, D. Metzke, T. Wojciechowicz, K.W. Nowak, M.Z. Strowski. Capsaicin induces cytotoxicity in pancreatic neuroendocrine tumor cells via mitochondrial action. Cellular Signalling 2014; 26(1): 41 doi: 10.1016/j.cellsig.2013.09.014
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37 |
Sun Young Kim, You Jin Lee, Eun Hye Park, Ho Keun Yi, Dae Sun Jo, Jung Soo Kim, Pyoung Han Hwang. Capsaicin induced apoptosis and the enhanced anticancer effect of anticancer drugs in cancer cells. Korean Journal of Pediatrics 2008; 51(3): 307 doi: 10.3345/kjp.2008.51.3.307
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38 |
So Ra Choi, Myung Jun Kim, Min Sil Ahn, Eun Ju Song, Sang Young Seo, Min Kyung Choi, Young Sun Kim, Dong Geun Choi, Young Ju Song. Cytotoxicity of Extracts from Korean Pepper (Capsicum annuum L.) by Extraction Solvents and Plant Parts. Korean Journal of Medicinal Crop Science 2014; 22(5): 369 doi: 10.7783/KJMCS.2014.22.5.369
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39 |
Keith Bley, Gary Boorman, Bashir Mohammad, Donald McKenzie, Sunita Babbar. A Comprehensive Review of the Carcinogenic and Anticarcinogenic Potential of Capsaicin. Toxicologic Pathology 2012; 40(6): 847 doi: 10.1177/0192623312444471
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40 |
Seok-Cheol Cho, Hyosung Lee, Bu Young Choi. An updated review on molecular mechanisms underlying the anticancer effects of capsaicin. Food Science and Biotechnology 2017; 26(1): 1 doi: 10.1007/s10068-017-0001-x
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41 |
Wimonrat Panpetch, Peerapat Visitchanakun, Wilasinee Saisorn, Ajcharaporn Sawatpanich, Piraya Chatthanathon, Naraporn Somboonna, Somying Tumwasorn, Asada Leelahavanichkul, Pradeep Dudeja. Lactobacillus rhamnosus attenuates Thai chili extracts induced gut inflammation and dysbiosis despite capsaicin bactericidal effect against the probiotics, a possible toxicity of high dose capsaicin. PLOS ONE 2021; 16(12): e0261189 doi: 10.1371/journal.pone.0261189
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42 |
Kartick C. Pramanik, Sanjay K. Srivastava. Apoptosis Signal-Regulating Kinase 1–Thioredoxin Complex Dissociation by Capsaicin Causes Pancreatic Tumor Growth Suppression by Inducing Apoptosis. Antioxidants & Redox Signaling 2012; 17(10): 1417 doi: 10.1089/ars.2011.4369
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43 |
Samik Chakraborty, Minakshi Mazumdar, Shravanti Mukherjee, Pushpak Bhattacharjee, Arghya Adhikary, Argha Manna, Sreeparna Chakraborty, Poulami Khan, Aparna Sen, Tanya Das. Restoration of p53/miR‐34a regulatory axis decreases survival advantage and ensures Bax‐dependent apoptosis of non‐small cell lung carcinoma cells. FEBS Letters 2014; 588(4): 549 doi: 10.1016/j.febslet.2013.11.040
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44 |
Rajesh Sandu, Vijayapandi Pandy. Capsaicin: A review of its pharmacology in gastrointestinal health and disorders. Pharmacological Research - Natural Products 2024; 5: 100103 doi: 10.1016/j.prenap.2024.100103
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45 |
Pompy Patowary, Manash Pratim Pathak, Kamaruz Zaman, P.S. Raju, Pronobesh Chattopadhyay. Research progress of capsaicin responses to various pharmacological challenges. Biomedicine & Pharmacotherapy 2017; 96: 1501 doi: 10.1016/j.biopha.2017.11.124
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46 |
N H Thoennissen, J O'Kelly, D Lu, G B Iwanski, D T La, S Abbassi, A Leiter, B Karlan, R Mehta, H P Koeffler. Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway. Oncogene 2010; 29(2): 285 doi: 10.1038/onc.2009.335
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47 |
Katrin Sak, Kadi Jürisoo, Ain Raal. Estonian folk traditional experiences on natural anticancer remedies: From past to the future. Pharmaceutical Biology 2014; 52(7): 855 doi: 10.3109/13880209.2013.871641
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