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For: Tang KS, Chiu HF, Chen HH, Eng HL, Tsai CJ, Teng HC, Huang CS. Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes. World J Gastroenterol 2005; 11(21): 3250-3254 [PMID: 15929176 DOI: 10.3748/wjg.v11.i21.3250]
URL: https://www.wjgnet.com/1007-9327/full/v11/i21/3250.htm
Number Citing Articles
1
Nazlisadat Seyed Khoei, Gabriele Anton, Annette Peters, Heinz Freisling, Karl-Heinz Wagner. The Association between Serum Bilirubin Levels and Colorectal Cancer Risk: Results from the Prospective Cooperative Health Research in the Region of Augsburg (KORA) Study in GermanyAntioxidants 2020; 9(10): 908 doi: 10.3390/antiox9100908
2
Paula R. Pacheco, Maria J. Brilhante, Cristina Ballart, Francesc Sigalat, Helena Polena, Rita Cabral, Claudia C. Branco, Luisa Mota-Vieira. UGT1A1, UGT1A6 and UGT1A7 Genetic AnalysisMolecular Diagnosis & Therapy 2009; 13(4): 261 doi: 10.1007/BF03256331
3
Nazlisadat Seyed Khoei, Mazda Jenab, Neil Murphy, Barbara L. Banbury, Robert Carreras-Torres, Vivian Viallon, Tilman Kühn, Bas Bueno-de-Mesquita, Krasimira Aleksandrova, Amanda J. Cross, Elisabete Weiderpass, Magdalena Stepien, Andrew Bulmer, Anne Tjønneland, Marie-Christine Boutron-Ruault, Gianluca Severi, Franck Carbonnel, Verena Katzke, Heiner Boeing, Manuela M. Bergmann, Antonia Trichopoulou, Anna Karakatsani, Georgia Martimianaki, Domenico Palli, Giovanna Tagliabue, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Guri Skeie, Susana Merino, Catalina Bonet, Miguel Rodríguez-Barranco, Leire Gil, Maria-Dolores Chirlaque, Eva Ardanaz, Robin Myte, Johan Hultdin, Aurora Perez-Cornago, Dagfinn Aune, Konstantinos K. Tsilidis, Demetrius Albanes, John A. Baron, Sonja I. Berndt, Stéphane Bézieau, Hermann Brenner, Peter T. Campbell, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Stephen J. Chanock, Michelle Cotterchio, Steven Gallinger, Stephen B. Gruber, Robert W. Haile, Jochen Hampe, Michael Hoffmeister, John L. Hopper, Li Hsu, Jeroen R. Huyghe, Mark A. Jenkins, Amit D. Joshi, Ellen Kampman, Susanna C. Larsson, Loic Le Marchand, Christopher I. Li, Li Li, Annika Lindblom, Noralane M. Lindor, Vicente Martín, Victor Moreno, Polly A. Newcomb, Kenneth Offit, Shuji Ogino, Patrick S. Parfrey, Paul D. P. Pharoah, Gad Rennert, Lori C. Sakoda, Clemens Schafmayer, Stephanie L. Schmit, Robert E. Schoen, Martha L. Slattery, Stephen N. Thibodeau, Cornelia M. Ulrich, Franzel J. B. van Duijnhoven, Korbinian Weigl, Stephanie J. Weinstein, Emily White, Alicja Wolk, Michael O. Woods, Anna H. Wu, Xuehong Zhang, Pietro Ferrari, Gabriele Anton, Annette Peters, Ulrike Peters, Marc J. Gunter, Karl-Heinz Wagner, Heinz Freisling. Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analysesBMC Medicine 2020; 18(1) doi: 10.1186/s12916-020-01703-w
4
S Nagar, R P Remmel. Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancerOncogene 2006; 25(11): 1659 doi: 10.1038/sj.onc.1209375
5
Pei-Hua Lu, Min-Bin Chen, Xiao-Yang Wu, Jin-Hua Gu, Yuan Liu, Rong-min Gu. Genetic Polymorphisms of UGT1A7 and Cancer Risk: Evidence From 21 Case–Control StudiesCancer Investigation 2011; 29(10): 645 doi: 10.3109/07357907.2011.626477
6
Sun‐Young Bae, Sun‐Keun Choi, Kyung‐Rae Kim, Chang‐Shin Park, Sung‐Keun Lee, Hyung‐Keun Roh, Dong‐Woon Shin, Jae‐Eun Pie, Ze‐Hong Woo, Ju‐Hee Kang. Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in KoreansCancer Science 2006; 97(8): 774 doi: 10.1111/j.1349-7006.2006.00241.x
7
Vincent Ménard, Hugo Girard, Mario Harvey, Louis Pérusse, Chantal Guillemette. Analysis of inherited genetic variations at theUGT1locus in the French-Canadian populationHuman Mutation 2009; 30(4): 677 doi: 10.1002/humu.20946
8
Yung-Sung Yeh, Hsiang-Lin Tsai, Ching-Wen Huang, Jui-Ho Wang, Yi-Wen Lin, Hsiu-Chih Tang, Yung-Chuan Sung, Chang-Chieh Wu, Chien-Yu Lu, Jaw-Yuan Wang. Prospective analysis of UGT1A1 promoter polymorphism for irinotecan dose escalation in metastatic colorectal cancer patients treated with bevacizumab plus FOLFIRI as the first-line setting: study protocol for a randomized controlled trialTrials 2016; 17(1) doi: 10.1186/s13063-016-1153-3
9
Min Wang, De-Feng Sun, Shuai Wang, Ying Qing, Shuo Chen, Dong Wu, Ying-Min Lin, Ji-Zhuang Luo, Yan-Qing Li, Hiromu Suzuki. Polymorphic Expression of UDP-Glucuronosyltransferase UGTlA Gene in Human Colorectal CancerPLoS ONE 2013; 8(2): e57045 doi: 10.1371/journal.pone.0057045
10
Shu‐Qi Yang, Yi‐Jie Lin, Hua‐Tang Zhang, Xing Wang, Yan‐Yan Qiu, Yan‐Yan Lin, Xue‐Ping Yu. A Case Report of Gilbert Syndrome Presenting With Acute CholecystitisClinical Case Reports 2025; 13(3) doi: 10.1002/ccr3.70290
11
Christian P. Strassburg, Sandra Kalthoff, Ursula Ehmer. Variability and Function of Family 1 Uridine-5′-Diphosphate Glucuronosyltransferases (UGT1A)Critical Reviews in Clinical Laboratory Sciences 2008; 45(6): 485 doi: 10.1080/10408360802374624
12
Tim O. Lankisch, Christoph Schulz, Thomas Zwingers, Thomas J. Erichsen, Michael P. Manns, Volker Heinemann, Christian P. Strassburg. Gilbert's Syndrome and Irinotecan Toxicity: Combination with UDP-Glucuronosyltransferase 1A7 Variants Increases RiskCancer Epidemiology, Biomarkers & Prevention 2008; 17(3): 695 doi: 10.1158/1055-9965.EPI-07-2517
13
Keizo Ohnaka, Suminori Kono. Bilirubin, cardiovascular diseases and cancer: epidemiological perspectivesExpert Review of Endocrinology & Metabolism 2010; 5(6): 891 doi: 10.1586/eem.10.65
14
Hiromichi Maeda, Shoichi Hazama, Abdiev Shavkat, Ken Okamoto, Koji Oba, Junichi Sakamoto, Kenichi Takahashi, Masaki Oka, Daisuke Nakamura, Ryouichi Tsunedomi, Naoko Okayama, Hideyuki Mishima, Michiya Kobayashi. Differences in UGT1A1, UGT1A7, and UGT1A9 Polymorphisms between Uzbek and Japanese PopulationsMolecular Diagnosis & Therapy 2014; 18(3): 333 doi: 10.1007/s40291-014-0083-6
15
Shuang-Xi Han, Li Wang, De-Quan Wu. The association between UGT1A7 polymorphism and cancer risk: A meta-analysisCancer Epidemiology 2012; 36(4): e201 doi: 10.1016/j.canep.2012.02.004
16
Constance Lay Lay Saw, Ah-Ng Tony Kong. Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancerExpert Opinion on Therapeutic Targets 2011; 15(3): 281 doi: 10.1517/14728222.2011.553602
17
Ahmed El Bastawisy, Abeer Bahnasy, Amany El-Zeiny, Samar Farid. UGT1A1*28 Polymorphism in Advanced Colorectal Cancer: The Story Is Not Yet EndedJournal of Cancer Therapy 2014; 5(01): 53 doi: 10.4236/jct.2014.51007
18
R. Meech, D.-G. Hu, J.O. Miners, P.I. Mackenzie. Comprehensive Toxicology2018; : 468 doi: 10.1016/B978-0-12-801238-3.65733-1
19
Natnicha Wankaew, Pajaree Chariyavilaskul, Monpat Chamnanphon, Adjima Assawapitaksakul, Wanna Chetruengchai, Monnat Pongpanich, Vorasuk Shotelersuk, Laith Al-Eitan. Genotypic and phenotypic landscapes of 51 pharmacogenes derived from whole-genome sequencing in a Thai populationPLOS ONE 2022; 17(2): e0263621 doi: 10.1371/journal.pone.0263621
20
Yingshi Zhang, Jun Hou, Fan Feng, Dandan Li, Qiyu Jiang, Xiaojuan Li, Qingchun Zhao, Bo-An Li. Genetic polymorphisms in human UDP-glucuronosyltransferases 1A7 and the risk of gastrointestinal carcinomas: A systematic review and network meta-analysisOncotarget 2017; 8(39): 66371 doi: 10.18632/oncotarget.18675
21
Huma Mehboob, Imtiaz Mahmood Tahir, Tahir Iqbal, Naheed Akhter, Naveed Munir, Muhammad Riaz. Genetic Polymorphisms2017;  doi: 10.5772/intechopen.69206
22
P. Biason, S. Masier, G. Toffoli. UGT1A1*28 and Other UGT1A Polymorphisms as Determinants of Irinotecan ToxicityJournal of Chemotherapy 2008; 20(2): 158 doi: 10.1179/joc.2008.20.2.158
23
Andrea Y. Angstadt, Terryl J. Hartman, Samuel M. Lesko, Joshua E. Muscat, Junjia Zhu, Carla J. Gallagher, Philip Lazarus. The effect ofUGT1AandUGT2Bpolymorphisms on colorectal cancer risk: Haplotype associations and gene–environment interactionsGenes, Chromosomes and Cancer 2014; 53(6): 454 doi: 10.1002/gcc.22157
24
I Stücker, MA Loriot, G N'Koutchou, S Cénée, L Bodin, C Mulot, M Gelu-Simeon, L Pelletier, JP Bronowicki, F Degos, P Beaune, P Laurent-Puig, D Hémon, JC Trinchet, G Pelletier. UDP-glucuronosyltransferase UGT1A7 genetic polymorphisms in hepatocellular carcinoma: a differential impact according to seropositivity of HBV or HCV markers?BMC Cancer 2007; 7(1) doi: 10.1186/1471-2407-7-214
25
Xiaoqing Zhang, Guokun Ao, Yuewen Wang, Wei Yan, Min Wang, Erfei Chen, Fangfang Yang, Jin Yang. Genetic variants and haplotypes of the UGT1A9, 1A7 and 1A1 genes in Chinese HanGenetics and Molecular Biology 2012; 35(2): 428 doi: 10.1590/S1415-47572012005000036
26
Tomáš Vinař, Broňa Brejová, Giltae Song, Adam Siepel. Reconstructing Histories of Complex Gene Clusters on a PhylogenyJournal of Computational Biology 2010; 17(9): 1267 doi: 10.1089/cmb.2010.0090
27
Christian P. Strassburg. Hyperbilirubinemia syndromes (Gilbert-Meulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome)Best Practice & Research Clinical Gastroenterology 2010; 24(5): 555 doi: 10.1016/j.bpg.2010.07.007
28
Elham Babadi, Kamran Roudini, Kianmehr Aalipour, Olatunji B. Alese. The role of UGT1A1 polymorphism in the management of colorectal cancerOncology Reviews 2025; 19 doi: 10.3389/or.2025.1547904
29
Kayo Osawa, Chiaki Nakarai, Minami Akiyama, Ryuta Hashimoto, Akimitsu Tsutou, Juro Takahashi, Yuko Takaoka, Shiro Kawamura, Etsuji Shimada, Kenichi Tanaka, Masaya Kozuka, Masahiro Yamamoto, Yoshiaki Kido. Association between Polymorphisms in UDP-glucuronosyltransferase 1A6 and 1A7 and Colorectal Cancer RiskAsian Pacific Journal of Cancer Prevention 2012; 13(5): 2311 doi: 10.7314/APJCP.2012.13.5.2311
30
Robyn Meech, Dong Gui Hu, Ross A. McKinnon, Siti Nurul Mubarokah, Alex Z. Haines, Pramod C. Nair, Andrew Rowland, Peter I. Mackenzie. The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel ParadigmsPhysiological Reviews 2019; 99(2): 1153 doi: 10.1152/physrev.00058.2017
31
Dong Gui Hu, Peter I. Mackenzie, Ross A. McKinnon, Robyn Meech. Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer riskDrug Metabolism Reviews 2016; 48(1): 47 doi: 10.3109/03602532.2015.1131292
32
Kung-Sheng Tang, Chuan-Mo Lee, Hsiu-Chen Teng, May-Jen Huang, Ching-Shan Huang. UDP-glucuronosyltransferase 1A7 polymorphisms are associated with liver cirrhosisBiochemical and Biophysical Research Communications 2008; 366(3): 643 doi: 10.1016/j.bbrc.2007.11.125
33
Christian P. Strassburg. Gilbert-Meulengracht’s syndrome and pharmacogenetics: is jaundice just the tip of the iceberg?Drug Metabolism Reviews 2010; 42(1): 168 doi: 10.3109/03602530903209429
34
Serge Erlinger, Irwin M. Arias, Daniel Dhumeaux. Inherited Disorders of Bilirubin Transport and Conjugation: New Insights Into Molecular Mechanisms and ConsequencesGastroenterology 2014; 146(7): 1625 doi: 10.1053/j.gastro.2014.03.047
35
Ching-Shan Huang. Molecular genetics of unconjugated hyperbilirubinemia in TaiwaneseJournal of Biomedical Science 2005; 12(3): 445 doi: 10.1007/s11373-005-3863-5
36
Christian P Strassburg. Pharmacogenetics of Gilbert‘s SyndromePharmacogenomics 2008; 9(6): 703 doi: 10.2217/14622416.9.6.703
37
Tomáš Vinař, Broňa Brejová, Giltae Song, Adam Siepel. Comparative GenomicsLecture Notes in Computer Science 2009; 5817: 150 doi: 10.1007/978-3-642-04744-2_13
38
Marija Hiljadnikova Bajro, Toni Josifovski, Milco Panovski, Nikola Jankulovski, Aleksandra Kapedanovska Nestorovska, Nadica Matevska, Natalija Petrusevska, Aleksandar J. Dimovski. Promoter length polymorphism in UGT1A1 and the risk of sporadic colorectal cancerCancer Genetics 2012; 205(4): 163 doi: 10.1016/j.cancergen.2012.01.015
39
Julie-Ann Hulin, Dong-Gui Hu, John Oliver Miners, Peter Ian Mackenzie, Robyn Meech. Reference Module in Biomedical Sciences2024;  doi: 10.1016/B978-0-323-95488-4.00015-2
40
Tim O. Lankisch, Georg Behrens, Ursula Ehmer, Ulrike Möbius, Juergen Rockstroh, Michael Wehmeier, Sandra Kalthoff, Nicole Freiberg, Michael P. Manns, Reinhold E. Schmidt, Christian P. Strassburg. Gilbert’s syndrome and hyperbilirubinemia in protease inhibitor therapy – An extended haplotype of genetic variants increases risk in indinavir treatmentJournal of Hepatology 2009; 50(5): 1010 doi: 10.1016/j.jhep.2008.12.030
41
Latif Yilmaz, Ersin Borazan, Turkan Aytekin, Ilyas Baskonus, Alper Aytekin, Serdar Oztuzcu, Zehra Bozdag, Ahmet Balik. Increased UGT1A3 and UGT1A7 Expression is Associated with Pancreatic CancerAsian Pacific Journal of Cancer Prevention 2015; 16(4): 1651 doi: 10.7314/APJCP.2015.16.4.1651
42
Kai Yang, Zhi-Wei Fu, Yun-Feng Cao, Sai-Nan Li, Zuo Du, Xiao-Yu Sun, Yong-Zhe Liu, Kun Yang, Zhong-Ze Fang. New insights for risks of chlorophenols (CPs) exposure: Inhibition of UDP-glucuronosyltransferases (UGTs)Chemosphere 2018; 206: 9 doi: 10.1016/j.chemosphere.2018.04.148
43
Kazuki Yamamoto, Takashi Ikeya, Shuhei Okuyama, Takeshi Okamoto, Katsuyuki Fukuda, Daiki Kobayashi. Negative correlation of high serum bilirubin with cancer development in adults without hepatobiliary diseaseEuropean Journal of Cancer Prevention 2021; 30(1): 69 doi: 10.1097/CEJ.0000000000000643
44
Christian P. Strassburg. Therapie-Handbuch - Gastroenterologie und Hepatologie2024; : 466 doi: 10.1016/B978-3-437-21005-1.00061-5
45
Na Yang, Runbin Sun, Xiaoying Liao, Jiye Aa, Guangji Wang. UDP-glucuronosyltransferases (UGTs) and their related metabolic cross-talk with internal homeostasis: A systematic review of UGT isoforms for precision medicinePharmacological Research 2017; 121: 169 doi: 10.1016/j.phrs.2017.05.001
46
Chiara Pesenti, Milena Gusella, Silvia M. Sirchia, Monica Miozzo. Germline oncopharmacogenetics, a promising field in cancer therapyCellular Oncology 2015; 38(1): 65 doi: 10.1007/s13402-014-0214-4
47
P.I. Mackenzie, D.A. Gardner-Stephen, J.O. Miners. Comprehensive Toxicology2010; : 413 doi: 10.1016/B978-0-08-046884-6.00420-6
48
Christian P. Strassburg, Tim O. Lankisch, Michael P. Manns, Ursula Ehmer. Family 1 uridine-5′-diphosphate glucuronosyltransferases (UGT1A): from Gilbert’s syndrome to genetic organization and variabilityArchives of Toxicology 2008; 82(7): 415 doi: 10.1007/s00204-008-0314-x
49
Gary Ginsberg, Kathryn Guyton, Douglas Johns, Jennifer Schimek, Kenneth Angle, Babasaheb Sonawane. Genetic polymorphism in metabolism and host defense enzymes: Implications for human health risk assessmentCritical Reviews in Toxicology 2010; 40(7): 575 doi: 10.3109/10408441003742895
50
Christian P. Strassburg, Sandra Kalthoff. Metabolism of Drugs and Other Xenobiotics2012; : 67 doi: 10.1002/9783527630905.ch3
51
Huma Mehboob, Imtiaz Mahmood Tahir, Tahira Iqbal, Sadaf Saleem, Sofia Perveen, Aboubakker Farooqi. Effect of UDP-Glucuronosyltransferase (UGT) 1A Polymorphism (rs8330 and rs10929303) on Glucuronidation Status of AcetaminophenDose-Response 2017; 15(3): 155932581772373 doi: 10.1177/1559325817723731
52
S. Hamsa, Aarti Yadav, Ruby Tiwari, Tejpal Dhewa. Nutritional Science and Technology2023; : 335 doi: 10.1002/9781394229116.ch15