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For: Huang GW, Yang LY, Lu WQ. Expression of hypoxia-inducible factor 1α and vascular endothelial growth factor in hepatocellular carcinoma: Impact on neovascularization and survival. World J Gastroenterol 2005; 11(11): 1705-1708 [PMID: 15786555 DOI: 10.3748/wjg.v11.i11.1705]
URL: https://www.wjgnet.com/1007-9327/full/v11/i11/1705.htm
Number Citing Articles
1
Qi Zhang, Jiajun Wu, Xueli Bai, Tingbo Liang. Evaluation of Intra-Tumoral Vascularization in Hepatocellular CarcinomasFrontiers in Medicine 2020; 7 doi: 10.3389/fmed.2020.584250
2
Ni Zeng, Ye Wang, Yuan Wan, Hongyu Wang, Nan Li. The Antitumor Impact of Combining Hepatic Artery Ligation With Copper Chelators for Liver CancerClinical Medicine Insights: Oncology 2023; 17 doi: 10.1177/11795549231204612
3
Ahmed O. Kaseb, Amr Hanbali, Matthew Cotant, Manal M. Hassan, Ira Wollner, Philip A. Philip. Vascular endothelial growth factor in the management of hepatocellular carcinomaCancer 2009; 115(21): 4895 doi: 10.1002/cncr.24537
4
Piotr Jan Wysocki. Targeted therapy of hepatocellular cancerExpert Opinion on Investigational Drugs 2010; 19(2): 265 doi: 10.1517/13543780903514110
5
Ilias Mylonis, Achillia Lakka, Andreas Tsakalof, George Simos. The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditionsBiochemical and Biophysical Research Communications 2010; 398(1): 74 doi: 10.1016/j.bbrc.2010.06.038
6
Mona Malz, Federico Pinna, Peter Schirmacher, Kai Breuhahn. Transcriptional regulators in hepatocarcinogenesis – Key integrators of malignant transformationJournal of Hepatology 2012; 57(1): 186 doi: 10.1016/j.jhep.2011.11.029
7
Hiroki Tanaka, Masahiro Yamamoto, Norikazu Hashimoto, Masaaki Miyakoshi, Susumu Tamakawa, Masumi Yoshie, Yoshihiko Tokusashi, Kazunori Yokoyama, Yuji Yaginuma, Katsuhiro Ogawa. Hypoxia-Independent Overexpression of Hypoxia-Inducible Factor 1α as an Early Change in Mouse HepatocarcinogenesisCancer Research 2006; 66(23): 11263 doi: 10.1158/0008-5472.CAN-06-1699
8
Shereen El Shorbagy, Fouad abuTaleb, Hany A. Labib, Huda Ebian, Ola A. Harb, Mona Saeed Mohammed, Hanaa A. Rashied, Khaled A. Elbana, Rasha Haggag. Prognostic Significance of VEGF and HIF-1 α in Hepatocellular Carcinoma Patients Receiving Sorafenib Versus Metformin Sorafenib CombinationJournal of Gastrointestinal Cancer 2021; 52(1): 269 doi: 10.1007/s12029-020-00389-w
9
Eisuke Ueshima, Hideyuki Nishiofuku, Haruyuki Takaki, Yutaka Hirata, Hiroshi Kodama, Toshihiro Tanaka, Kimihiko Kichikawa, Koichiro Yamakado, Takuya Okada, Keitaro Sofue, Masato Yamaguchi, Koji Sugimoto, Takamichi Murakami. Hepatic Artery Embolization Induces the Local Overexpression of Transforming Growth Factor β1 in a Rat Hepatoma ModelLiver Cancer 2020; 9(1): 63 doi: 10.1159/000502774
10
Ahmed Kaseb, Melanie Thomas. Hepatocellular Carcinoma2009; : 114 doi: 10.3109/9780203092880-10
11
Jing Fu, Yao Chen, Jie Cao, Tao Luo, You-Wen Qian, Wen Yang, Yi-Bin Ren, Bo Su, Guang-Wen Cao, Yuan Yang, Yi-Qun Yan, Feng Shen, Meng-Chao Wu, Gen-Sheng Feng, Hong-Yang Wang. p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1α pathwaysHepatology 2011; 53(1): 181 doi: 10.1002/hep.24015
12
Sae Byeol Choi, Hyung Joon Han, Wan Bae Kim, Tae Jin Song, Sang Yong Choi. VEGF overexpression predicts poor survival in hepatocellular carcinomaOpen Medicine 2017; 12(1): 430 doi: 10.1515/med-2017-0061
13
Geng-Wen Huang, Yi-Ming Tao, Xiang Ding. Endocan Expression Correlated with Poor Survival in Human Hepatocellular CarcinomaDigestive Diseases and Sciences 2009; 54(2): 389 doi: 10.1007/s10620-008-0346-3
14
Yinsong Wang, Hongli Chen, Yuanyuan Liu, Jing Wu, Ping Zhou, Yan Wang, Rongshan Li, Xiaoying Yang, Ning Zhang. pH-sensitive pullulan-based nanoparticle carrier of methotrexate and combretastatin A4 for the combination therapy against hepatocellular carcinomaBiomaterials 2013; 34(29): 7181 doi: 10.1016/j.biomaterials.2013.05.081
15
Femke Heindryckx, Pär Gerwins. Targeting the tumor stroma in hepatocellular carcinomaWorld Journal of Hepatology 2015; 7(2): 165-176 doi: 10.4254/wjh.v7.i2.165
16
Y. Hu, H. E, X. Yu, F. Li, L. Zeng, Q. Lu, X. Xi, L. Shen. Correlation of quantitative parameters of magnetic resonance perfusion‐weighted imaging with vascular endothelial growth factor, microvessel density and hypoxia‐inducible factor‐1α in nasopharyngeal carcinoma: Evaluation on radiosensitivity studyClinical Otolaryngology 2018; 43(2): 425 doi: 10.1111/coa.12982
17
YAN SONG, LILI CAO. N-myc downstream-regulated gene 1: Diverse and complicated functions in human hepatocellular carcinoma (Review)Oncology Letters 2013; 6(6): 1539 doi: 10.3892/ol.2013.1636
18
Maria Rosaria Paravati, Giuseppe Guido Maria Scarlata, Maja Milanović, Nataša Milić, Ludovico Abenavoli. The anticancer activity of quercetin, luteolin, myricetin, and kaempferol in the development of hepatocellular carcinoma: a narrative reviewHepatoma Research 2024;  doi: 10.20517/2394-5079.2024.86
19
Bal Krishan Sharma, Radhika Srinivasan, Shweta Kapil, Bhupesh Singla, Yogesh Kumar Chawla, Anuradha Chakraborti, Nitin Saini, Ajay Duseja, Ashim Das, Naveen Kalra, Radha Krishan Dhiman. Angiogenic and anti-angiogenic factor gene transcript level quantitation by quantitative real time PCR in patients with hepatocellular carcinomaMolecular Biology Reports 2013; 40(10): 5843 doi: 10.1007/s11033-013-2690-4
20
Ronnie T. P. Poon, Cecilia Lau, Roberta Pang, Kelvin K. Ng, Jimmy Yuen, Sheung Tat Fan. High Serum Vascular Endothelial Growth Factor Levels Predict Poor Prognosis after Radiofrequency Ablation of Hepatocellular Carcinoma: Importance of Tumor Biomarker in Ablative TherapiesAnnals of Surgical Oncology 2007; 14(6): 1835 doi: 10.1245/s10434-007-9366-z
21
Antonio Diaz-Sanchez, Ana Matilla, Oscar Nuñez, Raquel Lorente, Alejandro Fernandez, Diego Rincón, Rocio Campos, Rafael Bañares, Gerardo Clemente. Serum angiopoietin-2 level as a predictor of tumor invasiveness in patients with hepatocellular carcinomaScandinavian Journal of Gastroenterology 2013; 48(3): 334 doi: 10.3109/00365521.2012.746391
22
Sheau-Fang Yang, Shen-Nien Wang, Chih-Fung Wu, Yao-Tsung Yeh, Chee-Yin Chai, Shih-Chang Chunag, Maw-Chang Sheen, King-Teh Lee. Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinomaJournal of Clinical Pathology 2007; 60(6): 642 doi: 10.1136/jcp.2006.036970
23
Maria Tampaki, Polyxeni P Doumba, Melanie Deutsch, John Koskinas. Circulating biomarkers of hepatocellular carcinoma response after locoregional treatments: New insightsWorld Journal of Hepatology 2015; 7(14): 1834-1842 doi: 10.4254/wjh.v7.i14.1834
24
Jian Kong, Jinge Kong, Bing Pan, Shan Ke, Shuying Dong, Xiuli Li, Aimin Zhou, Lemin Zheng, Wen-bing Sun, Mercedes Susan Mandell. Insufficient Radiofrequency Ablation Promotes Angiogenesis of Residual Hepatocellular Carcinoma via HIF-1α/VEGFAPLoS ONE 2012; 7(5): e37266 doi: 10.1371/journal.pone.0037266
25
Aki Pui-Wah Tse, Karen Man-Fong Sze, Queenie Tsung-Kwan Shea, Elley Yung-Tuen Chiu, Felice Ho-Ching Tsang, David Kung-Chun Chiu, Misty Shuo Zhang, Derek Lee, Iris Ming-Jing Xu, Cerise Yuen-Ki Chan, Hui-Yu Koh, Chun-Ming Wong, Yong-Ping Zheng, Irene Oi-Lin Ng, Carmen Chak-Lui Wong. Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancerOncogenesis 2018; 7(5) doi: 10.1038/s41389-018-0052-8
26
Daniela Valletta, Barbara Czech, Thilo Spruss, Kristian Ikenberg, Peter Wild, Arndt Hartmann, Thomas S. Weiss, Peter J. Oefner, Martina Müller, Anja-Katrin Bosserhoff, Claus Hellerbrand. Regulation and function of the atypical cadherin FAT1 in hepatocellular carcinomaCarcinogenesis 2014; 35(6): 1407 doi: 10.1093/carcin/bgu054
27
Feng Fang, Lai-Bang Luo, Yi-Ming Tao, Fan Wu, Lian-Yue Yang. Decreased Expression of Inhibitor of Growth 4 Correlated with Poor Prognosis of Hepatocellular CarcinomaCancer Epidemiology, Biomarkers & Prevention 2009; 18(2): 409 doi: 10.1158/1055-9965.EPI-08-0575
28
Elisa Pinto, Filippo Pelizzaro, Fabio Farinati, Francesco Paolo Russo. Angiogenesis and Hepatocellular Carcinoma: From Molecular Mechanisms to Systemic TherapiesMedicina 2023; 59(6): 1115 doi: 10.3390/medicina59061115
29
Jian-hai Guo, Xu Zhu, Xiao-ting Li, Ren-jie Yang. Impact of serum vascular endothelial growth factor on prognosis in patients with unresectable hepatocellular carcinoma after transarterial chemoembolizationChinese Journal of Cancer Research 2012; 24(1): 36 doi: 10.1007/s11670-012-0036-8
30
Yoichiro Matsuo, Qiang Ding, Ryosuke Desaki, Kosei Maemura, Yuko Mataki, Hiroyuki Shinchi, Shoji Natsugoe, Sonshin Takao. Hypoxia inducible factor‐1 alpha plays a pivotal role in hepatic metastasis of pancreatic cancer: an immunohistochemical studyJournal of Hepato-Biliary-Pancreatic Sciences 2014; 21(2): 105 doi: 10.1002/jhbp.6
31
Chunping Wang, Yinying Lu, Yan Chen, Yongyi Feng, Linjing An, Xinzhen Wang, Shuhui Su, Wenlin Bai, Lin Zhou, Yongping Yang, Dongping Xu. Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: a prospective studyClinical & Experimental Metastasis 2009; 26(7): 839 doi: 10.1007/s10585-009-9283-6
32
Ahmed W. Moawad, Ali Morshid, Ahmed M. Khalaf, Mohab M. Elmohr, John D. Hazle, David Fuentes, Mohamed Badawy, Ahmed O. Kaseb, Manal Hassan, Armeen Mahvash, Janio Szklaruk, Aliyya Qayyum, Abdelrahman Abusaif, William C. Bennett, Tracy S. Nolan, Brittney Camp, Khaled M. Elsayes. Multimodality annotated hepatocellular carcinoma data set including pre- and post-TACE with imaging segmentationScientific Data 2023; 10(1) doi: 10.1038/s41597-023-01928-3
33
Takayuki Shimizu, Ken-ichi Inoue, Hiroyuki Hachiya, Norisuke Shibuya, Mitsugi Shimoda, Keiichi Kubota. Frequent alteration of the protein synthesis of enzymes for glucose metabolism in hepatocellular carcinomasJournal of Gastroenterology 2014; 49(9): 1324 doi: 10.1007/s00535-013-0895-x
34
Nurbubu T. Moldogazieva, Innokenty M. Mokhosoev, Alexander A. Terentiev. Metabolic Heterogeneity of Cancer Cells: An Interplay between HIF-1, GLUTs, and AMPKCancers 2020; 12(4): 862 doi: 10.3390/cancers12040862
35
Ali Morshid, Khaled M. Elsayes, Ahmed M. Khalaf, Mohab M. Elmohr, Justin Yu, Ahmed O. Kaseb, Manal Hassan, Armeen Mahvash, Zhihui Wang, John D. Hazle, David Fuentes. A Machine Learning Model to Predict Hepatocellular Carcinoma Response to Transcatheter Arterial ChemoembolizationRadiology: Artificial Intelligence 2019; 1(5): e180021 doi: 10.1148/ryai.2019180021
36
G. W. Huang, X. Ding, S. L. Chen, L. Zeng. Expression of claudin 10 protein in hepatocellular carcinoma: impact on survivalJournal of Cancer Research and Clinical Oncology 2011; 137(8): 1213 doi: 10.1007/s00432-011-0987-z
37
Elisa Pinto, Filippo Pelizzaro, Romilda Cardin, Michele Battistel, Giorgio Palano, Federica Bertellini, Maria Piera Kitenge, Giulia Peserico, Fabio Farinati, Francesco Paolo Russo. HIF-1α and VEGF as prognostic biomarkers in hepatocellular carcinoma patients treated with transarterial chemoembolizationDigestive and Liver Disease 2024; 56(5): 872 doi: 10.1016/j.dld.2023.09.019
38
Lin Zhou, Jia Liu, Feng Luo. Serum tumor markers for detection of hepatocellular carcinomaWorld Journal of Gastroenterology 2006; 12(8): 1175-1181 doi: 10.3748/wjg.v12.i8.1175
39
Thomas K. Rhee, Joseph Y. Young, Andrew C. Larson, G. Kenneth Haines, Kent T. Sato, Riad Salem, Mary F. Mulcahy, Laura M. Kulik, Tatjana Paunesku, Gayle E. Woloschak, Reed A. Omary. Effect of Transcatheter Arterial Embolization on Levels of Hypoxia-inducible Factor-1α in Rabbit VX2 Liver TumorsJournal of Vascular and Interventional Radiology 2007; 18(5): 639 doi: 10.1016/j.jvir.2007.02.031
40
Sonja Sibold, Vincent Roh, Adrian Keogh, Peter Studer, Céline Tiffon, Eliane Angst, Stephan A. Vorburger, Rosemarie Weimann, Daniel Candinas, Deborah Stroka. Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinomaFEBS Letters 2007; 581(5): 989 doi: 10.1016/j.febslet.2007.01.080
41
Takashi Himoto, Koji Fujita, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Asahiro Morishita, Hirohito Yoneyama, Satoru Kubota, Reiji Haba, Yasuyuki Suzuki, Tsutomu Masaki. Roles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1αBiological Trace Element Research 2016; 174(1): 58 doi: 10.1007/s12011-016-0702-7
42
Ulrike Maegdefrau, Thomas Amann, Andreas Winklmeier, Simone Braig, Thomas Schubert, Thomas S Weiss, Katharina Schardt, Christina Warnecke, Claus Hellerbrand, Anja‐Katrin Bosserhoff. Bone morphogenetic protein 4 is induced in hepatocellular carcinoma by hypoxia and promotes tumour progressionThe Journal of Pathology 2009; 218(4): 520 doi: 10.1002/path.2563
43
Manuel Rodríguez-Perálvarez, Tu Vinh Luong, Lorenzo Andreana, Tim Meyer, Amar Paul Dhillon, Andrew Kenneth Burroughs. A Systematic Review of Microvascular Invasion in Hepatocellular Carcinoma: Diagnostic and Prognostic VariabilityAnnals of Surgical Oncology 2013; 20(1): 325 doi: 10.1245/s10434-012-2513-1
44
Carolina Méndez-Blanco, Paula Fernández-Palanca, Flavia Fondevila, Javier González-Gallego, José L. Mauriz. Prognostic and clinicopathological significance of hypoxia-inducible factors 1α and 2α in hepatocellular carcinoma: a systematic review with meta-analysisTherapeutic Advances in Medical Oncology 2021; 13 doi: 10.1177/1758835920987071
45
Hui Sheng, Minjie Mao, Kewei Huang, Hailin Zheng, Wen Liu, Yongneng Liang. A Clinical Tool to Predict the Microvascular Invasion Risk in Patients with Hepatocellular CarcinomaTechnology in Cancer Research & Treatment 2023; 22 doi: 10.1177/15330338231182526
46
Jennifer Wu, Merly Contratto, Krishna P Shanbhogue, Gulam A Manji, Bert H O’Neil, Anne Noonan, Robert Tudor, Ray Lee. Evaluation of a locked nucleic acid form of antisense oligo targeting HIF-1α in advanced hepatocellular carcinomaWorld Journal of Clinical Oncology 2019; 10(3): 149-160 doi: 10.5306/wjco.v10.i3.149
47
Zi‐Niu Ding, Zhao‐Ru Dong, Zhi‐Qiang Chen, Ya‐Fei Yang, Lun‐Jie Yan, Hai‐Chao Li, Kai‐Xuan Liu, Cheng‐Yu Yao, Yu‐Chuan Yan, Chun‐Cheng Yang, Tao Li. Effects of hypoxia‐inducible factor‐1α and hypoxia‐inducible factor‐2α overexpression on hepatocellular carcinoma survival: A systematic review with meta‐analysisJournal of Gastroenterology and Hepatology 2021; 36(6): 1487 doi: 10.1111/jgh.15395
48
Lauren E. Colbert, Sarah B. Fisher, Serdar Balci, Burcu Saka, Zhengjia Chen, Sungjin Kim, Bassel F. El-Rayes, N. Volkan Adsay, Shishir K. Maithel, Jerome C. Landry, Walter J. Curran. High Nuclear Hypoxia-Inducible Factor 1 Alpha Expression Is a Predictor of Distant Recurrence in Patients With Resected Pancreatic AdenocarcinomaInternational Journal of Radiation Oncology*Biology*Physics 2015; 91(3): 631 doi: 10.1016/j.ijrobp.2014.11.004
49
Mai M. Abdelmageed, Reem N. El-Naga, Ebtehal El-Demerdash, Mohamed M. Elmazar. Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic studyScientific Reports 2016; 6(1) doi: 10.1038/srep32733
50
Jui‐Chu Yang, Chiao‐Fang Teng, Han‐Chieh Wu, Hung‐Wen Tsai, Huai‐Chia Chuang, Ting‐Fen Tsai, Yung‐Hsiang Hsu, Wenya Huang, Li‐Wha Wu, Ih‐Jen Su. Enhanced expression of vascular endothelial growth factor‐A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis†Hepatology 2009; 49(6): 1962 doi: 10.1002/hep.22889
51
Gregg L. Semenza. Evaluation of HIF-1 inhibitors as anticancer agentsDrug Discovery Today 2007; 12(19-20): 853 doi: 10.1016/j.drudis.2007.08.006
52
Lei Guo, Hong Fang, Jim Collins, Xiao-hui Fan, Stacey Dial, Alex Wong, Kshama Mehta, Ernice Blann, Leming Shi, Weida Tong, Yvonne P Dragan. Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor α agonistsBMC Bioinformatics 2006; 7(S2) doi: 10.1186/1471-2105-7-S2-S18
53
Run AN, Jie MENG, Qi SHI, Xiao-Xia DAI, Jing-Hong CHEN, Yan-Jun LEI, Bing SHAN, Chen GAO, Yong-Lie CHU, Xiao-Ping DONG. Expressions of Nucleoside Diphosphate Kinase (nm23) in Tumor Tissues are Related with Metastasis and Length of Survival of Patients with Hepatocellular CarcinomaBiomedical and Environmental Sciences 2010; 23(4): 267 doi: 10.1016/S0895-3988(10)60062-1
54
Yang‑Ling Li, Ming‑Jun Rao, Ning‑Yu Zhang, Lin‑Wen Wu, Neng‑Ming Lin, Chong Zhang. BAY 87‑2243 sensitizes hepatocellular carcinoma Hep3B cells to histone deacetylase inhibitors treatment via GSK‑3β activationExperimental and Therapeutic Medicine 2019;  doi: 10.3892/etm.2019.7500
55
Ana Campillo, Estela Solanas, Maria J. Morandeira, Tomas Castiella, Sara Lorente, Francisco Agustín Garcia-Gil, Elena Piazuelo, Alba de Martino, Maria T. Serrano. Angiogenesis and proliferation markers in adjacent cirrhotic tissue could predict hepatocellular carcinoma outcome after liver transplantationEuropean Journal of Gastroenterology & Hepatology 2014; 26(8): 871 doi: 10.1097/MEG.0000000000000131
56
Gui-Bo Wang, Xin-Yu Zhou, Xiao-Qin Wang. Relationship Between Serum Heparanase and Microscopic Venous Invasion in Patients With Hepatocellular CarcinomaAmerican Journal of Clinical Pathology 2010; 134(2): 242 doi: 10.1309/AJCPPJM6VHG4LPJX
57
Yang-ling Li, Ning-yu Zhang, Xiu Hu, Jia-ling Chen, Ming-jun Rao, Lin-wen Wu, Qing-yu Li, Bo Zhang, Wei Yan, Chong Zhang. Evodiamine induces apoptosis and promotes hepatocellular carcinoma cell death induced by vorinostat via downregulating HIF-1α under hypoxiaBiochemical and Biophysical Research Communications 2018; 498(3): 481 doi: 10.1016/j.bbrc.2018.03.004
58
Zhen Song, Tengfei Liu, Jing Chen, Chao Ge, Fangyu Zhao, Miaoxin Zhu, Taoyang Chen, Ying Cui, Hua Tian, Ming Yao, Jinjun Li, Hong Li. HIF-1α-induced RIT1 promotes liver cancer growth and metastasis and its deficiency increases sensitivity to sorafenibCancer Letters 2019; 460: 96 doi: 10.1016/j.canlet.2019.06.016
59
Asako Kimura, Kazuyuki Sogawa, Mamoru Satoh, Yoshio Kodera, Osamu Yokosuka, Takeshi Tomonaga, Fumio Nomura. The Application of a Three-Step Serum Proteome Analysis for the Discovery and Identification of Novel Biomarkers of Hepatocellular CarcinomaInternational Journal of Proteomics 2012; 2012: 1 doi: 10.1155/2012/623190
60
Jacinth Wing-Sum Cheu, David Kung-Chun Chiu, Kenneth Kin-Leung Kwan, Chunxue Yang, Vincent Wai-Hin Yuen, Chi Ching Goh, Noreen Nog-Qin Chui, Wei Shen, Cheuk-Ting Law, Qidong Li, Misty Shuo Zhang, Macus Hao-Ran Bao, Bowie Po-Yee Wong, Cerise Yuen-Ki Chan, Cindy Xinqi Liu, Grace Fu-Wan Sit, Zher Yee Ooi, Haijing Deng, Aki Pui-Wah Tse, Irene Oi-Lin Ng, Carmen Chak-Lui Wong. Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer developmentScience Advances 2023; 9(18) doi: 10.1126/sciadv.ade5111
61
Yuji Morine, Mitsuo Shimada, Shuichi Iwahashi, Tohru Utsunomiya, Satoru Imura, Tetsuya Ikemoto, Hiroki Mori, Jun Hanaoka, Hidenori Miyake. Role of histone deacetylase expression in intrahepatic cholangiocarcinomaSurgery 2012; 151(3): 412 doi: 10.1016/j.surg.2011.07.038
62
Shiyi Cao, Shengli Yang, Chao Wu, Yunxia Wang, Jianxin Jiang, Zuxun Lu. Protein expression of hypoxia-inducible factor-1 alpha and hepatocellular carcinoma: A systematic review with meta-analysisClinics and Research in Hepatology and Gastroenterology 2014; 38(5): 598 doi: 10.1016/j.clinre.2014.04.004
63
Ruyue Ji, Chih-Ling Chou, Wei Xu, Xiao-Bo Chen, David F. Woodward, John W. Regan. EP1 Prostanoid Receptor Coupling to Gi/oUp-Regulates the Expression of Hypoxia-Inducible Factor-1α through Activation of a Phosphoinositide-3 Kinase Signaling PathwayMolecular Pharmacology 2010; 77(6): 1025 doi: 10.1124/mol.110.063933
64
Yanqiong Liu, Jingzhe Sui, Limin Zhai, Shi Yang, Li Huang, Liying Huang, Cuiju Mo, Junrong Wu, Shan Li, Xue Qin. Genetic polymorphisms in hypoxia-inducible factor-1a gene and its association with HBV-related hepatocellular carcinoma in a Chinese populationMedical Oncology 2014; 31(10) doi: 10.1007/s12032-014-0200-8
65
SEVGI BOZOVA, GÜLSÜM ÖZLEM ELPEK. Hypoxia‐inducible factor‐1α expression in experimental cirrhosis: correlation with vascular endothelial growth factor expression and angiogenesisAPMIS 2007; 115(7): 795 doi: 10.1111/j.1600-0463.2007.apm_610.x
66
Erdenebulgan Batmunkh, Mitsuo Shimada, Yuji Morine, Satoru Imura, Hirofumi Kanemura, Yusuke Arakawa, Jun Hanaoka, Mami Kanamoto, Koji Sugimoto, Masaaki Nishi. Expression of hypoxia-inducible factor-1 alpha (HIF-1α) in patients with the gallbladder carcinomaInternational Journal of Clinical Oncology 2010; 15(1): 59 doi: 10.1007/s10147-009-0011-7
67
Audrey Lequeux, Muhammad Zaeem Noman, Malina Xiao, Delphine Sauvage, Kris Van Moer, Elodie Viry, Irene Bocci, Meriem Hasmim, Manon Bosseler, Guy Berchem, Bassam Janji. Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpointsCancer Letters 2019; 458: 13 doi: 10.1016/j.canlet.2019.05.021
68
Lei Wang, Jin-lin Peng. Association of hypoxia-inducible factor 1α expression with susceptibility to hepatitis B virus-related hepatocellular carcinoma: A meta-analysisThe International Journal of Biological Markers 2023; 38(3-4): 149 doi: 10.1177/03936155231204391
69
Femke Heindryckx, Stephanie Coulon, Ellen Terrie, Christophe Casteleyn, Jean-Marie Stassen, Anja Geerts, Louis Libbrecht, Joke Allemeersch, Peter Carmeliet, Isabelle Colle, Hans Van Vlierberghe. The placental growth factor as a target against hepatocellular carcinoma in a diethylnitrosamine-induced mouse modelJournal of Hepatology 2013; 58(2): 319 doi: 10.1016/j.jhep.2012.09.032
70
Carmen Chak-Lui Wong, Alan Ka-Lun Kai, Irene Oi-Lin Ng. The impact of hypoxia in hepatocellular carcinoma metastasisFrontiers of Medicine 2014; 8(1): 33 doi: 10.1007/s11684-013-0301-3
71
Danbi Lee, Myoung-Kuk Jang, Ji Hae Seo, Soo Hyung Ryu, Jeong A. Kim, Young-Hwa Chung. ARD1/NAA10 in hepatocellular carcinoma: pathways and clinical implicationsExperimental & Molecular Medicine 2018; 50(7): 1 doi: 10.1038/s12276-018-0106-1
72
Sumeet Virmani, Thomas K. Rhee, Robert K. Ryu, Kent T. Sato, Robert J. Lewandowski, Mary F. Mulcahy, Laura M. Kulik, Barbara Szolc-Kowalska, Gayle E. Woloschak, Guang-Yu Yang, Riad Salem, Andrew C. Larson, Reed A. Omary. Comparison of Hypoxia-inducible Factor-1α Expression before and after Transcatheter Arterial Embolization in Rabbit VX2 Liver TumorsJournal of Vascular and Interventional Radiology 2008; 19(10): 1483 doi: 10.1016/j.jvir.2008.06.017
73
Thomas Amann, Ulrike Maegdefrau, Arndt Hartmann, Abbas Agaimy, Jörg Marienhagen, Thomas S. Weiss, Oliver Stoeltzing, Christina Warnecke, Jürgen Schölmerich, Peter J. Oefner, Marina Kreutz, Anja K. Bosserhoff, Claus Hellerbrand. GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes TumorigenesisThe American Journal of Pathology 2009; 174(4): 1544 doi: 10.2353/ajpath.2009.080596
74
Ender G. Yegin, Aydos Siykhymbayev, Fatih Eren, Nural Bekiroglu, Osman Cavit Ozdogan. Prognostic implication of serum vascular endothelial growth factor in advanced hepatocellular carcinoma stagingAnnals of Hepatology 2013; 12(6): 915 doi: 10.1016/S1665-2681(19)31297-9
75
Jin Un Kim, Mohamed I F Shariff, Mary M E Crossey, Maria Gomez-Romero, Elaine Holmes, I Jane Cox, Haddy K S Fye, Ramou Njie, Simon D Taylor-Robinson. Hepatocellular carcinoma: Review of disease and tumor biomarkersWorld Journal of Hepatology 2016; 8(10): 471-484 doi: 10.4254/wjh.v8.i10.471
76
Ivan Chebib, Meer Taher Shabani-Rad, Michelle S. Chow, James Zhang, Zu-hua Gao. Microvessel Density and Clinicopathologic Characteristics in Hepatocellular Carcinoma with and without CirrhosisBiomarker Insights 2007; 2: 117727190700200 doi: 10.1177/117727190700200013
77
Rashmi Nagesh, Rajeshwari H. Patil, M. Naveen Kumar, K.M. Kiran Kumar, Shivaleela Biradar, Babu R. Lamani. Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 22022; : 165 doi: 10.1016/B978-0-323-98807-0.00014-4
78
David J. Pinato, Mario Pirisi, Lynn Maslen, Rohini Sharma. Tissue Biomarkers of Prognostic Significance in Hepatocellular CarcinomaAdvances in Anatomic Pathology 2014; 21(4): 270 doi: 10.1097/PAP.0000000000000029
79
Fabio Grizzi, Barbara Franceschini, Cody Hamrick, Eldo E Frezza, Everardo Cobos, Maurizio Chiriva-Internati. Usefulness of cancer-testis antigens as biomarkers for the diagnosis and treatment of hepatocellular carcinomaJournal of Translational Medicine 2007; 5(1) doi: 10.1186/1479-5876-5-3
80
Lian-Yue Yang, Feng Fang, Di-Peng Ou, Wei Wu, Zhi-Jun Zeng, Fan Wu. Solitary Large Hepatocellular CarcinomaAnnals of Surgery 2009; 249(1): 118 doi: 10.1097/SLA.0b013e3181904988
81
Dong-Dong Guo, Kun-Feng Xie, Xing-Jing Luo. Hypoxia-induced elevated NDRG1 mediates apoptosis through reprograming mitochondrial fission in HCCGene 2020; 741: 144552 doi: 10.1016/j.gene.2020.144552
82
Seung Kak Shin, Sujin Ryu, Seungyoon Nam, Seung Yeon Ha, Oh Sang Kwon, Yun Soo Kim, Se-Hee Kim, Ju Hyun Kim. Clinical Significance of Combined Epithelial–Mesenchymal Transition Markers Expression and Role of Rac1 in Hepatocellular CarcinomaInternational Journal of Molecular Sciences 2023; 24(2): 1765 doi: 10.3390/ijms24021765
83
Manojkumar Bupathi, Ahmed Kaseb, Funda Meric-Bernstam, Aung Naing. Hepatocellular carcinoma: Where there is unmet needMolecular Oncology 2015; 9(8): 1501 doi: 10.1016/j.molonc.2015.06.005
84
Joonho Jeong, Jung Gu Park, Kwang Ill Seo, Ji Hyun Ahn, Jae Chun Park, Byung Cheol Yun, Sang Uk Lee, Jin Wook Lee, Jong Hyouk Yun. Microvascular invasion may be the determining factor in selecting TACE as the initial treatment in patients with hepatocellular carcinomaMedicine 2021; 100(27): e26584 doi: 10.1097/MD.0000000000026584
85
Y-G Yoo, T-Y Na, H-W Seo, J K Seong, C K Park, Y K Shin, M-O Lee. Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cellsOncogene 2008; 27(24): 3405 doi: 10.1038/sj.onc.1211000
86
Ya-Ling Hsu, Po-Lin Kuo, Chien-Yu Cho, Wen-Chiu Ni, Tz-Fei Tzeng, Lean-Teik Ng, Yueh-Hsiung Kuo, Chun-Ching Lin. Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor κB pathwayFood and Chemical Toxicology 2007; 45(7): 1249 doi: 10.1016/j.fct.2007.01.005
87
Vincent Wai-Hin Yuen, Carmen Chak-Lui Wong. Hypoxia-inducible factors and innate immunity in liver cancerJournal of Clinical Investigation 2020; 130(10): 5052 doi: 10.1172/JCI137553
88
Zhen Fan Yang, Ronnie T.P. Poon. Vascular Changes in Hepatocellular CarcinomaThe Anatomical Record 2008; 291(6): 721 doi: 10.1002/ar.20668
89
S.-L. Yang, L.-P. Liu, J.-X. Jiang, Z.-F. Xiong, Q.-J. He, C. Wu. The Correlation of Expression Levels of HIF-1  and HIF-2  in Hepatocellular Carcinoma with Capsular Invasion, Portal Vein Tumor Thrombi and Patients' Clinical OutcomeJapanese Journal of Clinical Oncology 2014; 44(2): 159 doi: 10.1093/jjco/hyt194
90
Zhong-Lin Zhang, Zhi-Su Liu, Quan Sun. Expression of angiopoietins, Tie2 and vascular endothelial growth factor in angiogenesis and progression of hepatocellular carcinomaWorld Journal of Gastroenterology 2006; 12(26): 4241-4245 doi: 10.3748/wjg.v12.i26.4241
91
Yufu Tang, Shupeng Liu, Nan Li, Weixing Guo, Jie Shi, Hongming Yu, Long Zhang, Kang Wang, Shangrong Liu, Shuqun Cheng. 14-3-3ζ promotes hepatocellular carcinoma venous metastasis by modulating hypoxia-inducible factor-1αOncotarget 2016; 7(13): 15854 doi: 10.18632/oncotarget.7493
92
R Ji, CM Sanchez, CL Chou, XB Chen, DF Woodward, JW Regan. Prostanoid EP1 receptors mediate up‐regulation of the orphan nuclear receptor Nurr1 by cAMP‐independent activation of protein kinase A, CREB and NF‐κBBritish Journal of Pharmacology 2012; 166(3): 1033 doi: 10.1111/j.1476-5381.2011.01817.x
93
Christopher D. Mann, Christopher P. Neal, Giuseppe Garcea, Margaret M. Manson, Ashley R. Dennison, David P. Berry. Prognostic molecular markers in hepatocellular carcinoma: A systematic reviewEuropean Journal of Cancer 2007; 43(6): 979 doi: 10.1016/j.ejca.2007.01.004
94
Su-Su Zheng, Xiao-Hong Chen, Xin Yin, Bo-Heng Zhang, William B. Coleman. Prognostic Significance of HIF-1α Expression in Hepatocellular Carcinoma: A Meta-AnalysisPLoS ONE 2013; 8(6): e65753 doi: 10.1371/journal.pone.0065753
95
Melanie Thomas. Molecular targeted therapy for hepatocellular carcinomaJournal of Gastroenterology 2009; 44(S19): 136 doi: 10.1007/s00535-008-2252-z
96
Pei‐Ching Hsiao, Mu‐Kuan Chen, Shih‐Chi Su, Kwo‐Chang Ueng, Yi‐Chen Chen, Yi‐Hsien Hsieh, Yu‐Fan Liu, Hsiu‐Ting Tsai, Shun‐Fa Yang. Hypoxia inducible factor‐1α gene polymorphism G1790A and its interaction with tobacco and alcohol consumptions increase susceptibility to hepatocellular carcinomaJournal of Surgical Oncology 2010; 102(2): 163 doi: 10.1002/jso.21539
97
Chung Doan, Long Le, Son Hoang, Si Do, Dong Le. Simultaneous silencing of VEGF and KSP by siRNA cocktail inhibits proliferation and induces apoptosis of hepatocellular carcinoma Hep3B cellsBiological Research 2014; 47(1): 70 doi: 10.1186/0717-6287-47-70
98
A.M. Khalaf, D. Fuentes, A. Morshid, A.O. Kaseb, M. Hassan, J.D. Hazle, K.M. Elsayes. Hepatocellular carcinoma response to transcatheter arterial chemoembolisation using automatically generated pre-therapeutic tumour volumes by a random forest-based segmentation protocolClinical Radiology 2019; 74(12): 974.e13 doi: 10.1016/j.crad.2019.07.023
99
Heng Xiao, Rongliang Tong, Shaobing Cheng, Zhen Lv, Chaofeng Ding, Chengli Du, Haiyang Xie, Lin Zhou, Jian Wu, Shusen Zheng. BAG3 and HIF-1αCoexpression Detected by Immunohistochemistry Correlated with Prognosis in Hepatocellular Carcinoma after Liver TransplantationBioMed Research International 2014; 2014: 1 doi: 10.1155/2014/516518
100
Stefania Cannito, Umberto Dianzani, Maurizio Parola, Emanuele Albano, Salvatore Sutti. Inflammatory processes involved in NASH-related hepatocellular carcinomaBioscience Reports 2023; 43(1) doi: 10.1042/BSR20221271
101
Hoang Van Tong, Pham Van Dung, Nguyen Thi Mong Diep, Nguyen Linh Toan. Hepatocellular Carcinoma - Challenges and Opportunities of a Multidisciplinary Approach2022;  doi: 10.5772/intechopen.98483
102
Meicheng Chen, Xiaoqi Zhou, Huasong Cai, Di Li, Chenyu Song, Huayu You, Ruixia Ma, Zhi Dong, Zhenpeng Peng, Shi‐Ting Feng. Evaluation of Hypoxia in Hepatocellular Carcinoma Using QuantitativeMRI: Significances, Challenges, and AdvancesJournal of Magnetic Resonance Imaging 2023; 58(1): 12 doi: 10.1002/jmri.28694
103
Weiguang Xu, Jung-Hee Kwon, Young Ho Moon, Young Bae Kim, Yun Suk Yu, Namgyu Lee, Kwan Yong Choi, Yun Soo Kim, Yong Keun Park, Bong Wan Kim, Hee Jung Wang. Influence of preoperative transcatheter arterial chemoembolization on gene expression in the HIF-1α pathway in patients with hepatocellular carcinomaJournal of Cancer Research and Clinical Oncology 2014; 140(9): 1507 doi: 10.1007/s00432-014-1713-4
104
Asmaa I Gomaa, Shahid A Khan, Edward LS Leen, Imam Waked, Simon D Taylor-Robinson. Diagnosis of hepatocellular carcinomaWorld Journal of Gastroenterology 2009; 15(11): 1301-1314 doi: 10.3748/wjg.15.1301
105
Frank Simon, Maximilian Bockhorn, Christian Praha, Hideo A. Baba, Christoph E. Broelsch, Andrea Frilling, Frank Weber. Deregulation of HIF1-alpha and hypoxia-regulated pathways in hepatocellular carcinoma and corresponding non-malignant liver tissue—influence of a modulated host stroma on the prognosis of HCCLangenbeck's Archives of Surgery 2010; 395(4): 395 doi: 10.1007/s00423-009-0590-9
106
Jung Hwa Lim, Dae-Ghon Kim, Dae-Yeul Yu, Hyun Mi Kang, Kyung Hee Noh, Dae-Soo Kim, Dongmin Park, Tae Kyung Chang, Dong-Soo Im, Cho-Rok Jung. Stabilization of E2-EPF UCP protein is implicated in hepatitis B virus-associated hepatocellular carcinoma progressionCellular and Molecular Life Sciences 2019; 76(13): 2647 doi: 10.1007/s00018-019-03066-9
107
Smruti Mohanty, Donald Jensen. Hepatocellular Carcinoma2009; : 62 doi: 10.3109/9780203092880-6
108
Sylene C.R. Carvalho, Luydson R.S. Vasconcelos, Leonardo da Fonseca, Rodrigo F. Carmo, Michele T. Tomitão, Dayse C.B.L. Aroucha, Leila M.M.B. Pereira, José Tadeu Stefano, Ulysses Ribeiro-Júnior, Claudia P. Oliveira, Flair J. Carrilho. Methylene tetrahydrofolate reductase (MTHFR) and vascular endothelial growth factor (VEGF) polymorphisms in Brazilian patients with Hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC)Clinics 2021; 76: e2881 doi: 10.6061/clinics/2021/e2881
109
Xinrui Yan, Mei-Sze Chua, Hongbo Sun, Samuel So. N-Myc down-regulated gene 1 mediates proliferation, invasion, and apoptosis of hepatocellular carcinoma cellsCancer Letters 2008; 262(1): 133 doi: 10.1016/j.canlet.2007.12.010
110
YAN-YAN SONG, LI-DAN SUN, MIN-LI LIU, ZHONG-LIANG LIU, FEI CHEN, YING-ZHE ZHANG, YAN ZHENG, JIAN-PING ZHANG. STAT3, p-STAT3 and HIF-1α are associated with vasculogenic mimicry and impact on survival in gastric adenocarcinomaOncology Letters 2014; 8(1): 431 doi: 10.3892/ol.2014.2059
111
Carmen Oi-ning Leung, Carmen Chak-lui Wong, Dorothy Ngo-yin Fan, Alan Ka-lun Kai, Edmund Kwok-kwan Tung, Iris Ming-jing Xu, Irene Oi-lin Ng, Regina Cheuk-lam Lo. PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinomaOncotarget 2015; 6(13): 10880 doi: 10.18632/oncotarget.3534
112
Bal Krishan Sharma, Radhika Srinivasan, Shweta Kapil, Bhupesh Singla, Nitin Saini, Yogesh Kumar Chawla, Anuradha Chakraborti, Ajay Duseja, Naveen Kalra, Radha Krishan Dhiman. Serum levels of angiogenic and anti-angiogenic factors: their prognostic relevance in locally advanced hepatocellular carcinomaMolecular and Cellular Biochemistry 2013; 383(1-2): 103 doi: 10.1007/s11010-013-1759-7
113
Femke Heindryckx, Eliene Bogaerts, Stephanie H. Coulon, Hilde Devlies, Anja M. Geerts, Louis Libbrecht, Jean Marie Stassen, Peter Carmeliet, Isabelle O. Colle, Hans R. Van Vlierberghe. Inhibition of the placental growth factor decreases burden of cholangiocarcinoma and hepatocellular carcinoma in a transgenic mouse modelEuropean Journal of Gastroenterology & Hepatology 2012; 24(9): 1020 doi: 10.1097/MEG.0b013e3283554219
114
Jun Muto, Ken Shirabe, Keishi Sugimachi, Yoshihiko Maehara. Review of angiogenesis in hepatocellular carcinomaHepatology Research 2015; 45(1): 1 doi: 10.1111/hepr.12310
115
Zhong-zhi Jia, Guo-min Jiang, Yao-liang Feng. Serum HIF-1α and VEGF Levels Pre- and Post-TACE in Patients with Primary Liver CancerChinese Medical Sciences Journal 2011; 26(3): 158 doi: 10.1016/S1001-9294(11)60041-2
116
Amedeo Sciarra, Maxime Ronot, Luca Di Tommaso, Carlotta Raschioni, Laurent Castera, Jacques Belghiti, Pierre Bedossa, Valérie Vilgrain, Massimo Roncalli, Valérie Paradis. TRIP: a pathological score for transarterial chemoembolization resistance individualized prediction in hepatocellular carcinomaLiver International 2015; 35(11): 2466 doi: 10.1111/liv.12844
117
Qiu-Ping Liu, Xun Xu, Fei-Peng Zhu, Yu-Dong Zhang, Xi-Sheng Liu. Prediction of prognostic risk factors in hepatocellular carcinoma with transarterial chemoembolization using multi-modal multi-task deep learningEClinicalMedicine 2020; 23: 100379 doi: 10.1016/j.eclinm.2020.100379
118
Etay Ziv, Yiru Zhang, Luke Kelly, Ines Nikolovski, F. Edward Boas, Joseph P. Erinjeri, Liqun Cai, Elena N. Petre, Lynn A. Brody, Anne M. Covey, George Getrajdman, James J. Harding, Constantinos Sofocleous, Ghassan K. Abou-Alfa, Stephen B. Solomon, Karen T. Brown, Hooman Yarmohammadi. NRF2 Dysregulation in Hepatocellular Carcinoma and Ischemia: A Cohort Study and Laboratory InvestigationRadiology 2020; 297(1): 225 doi: 10.1148/radiol.2020200201