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For: Ding Z, Qian YB, Zhu LX, Xiong QR. Promoter methylation and mRNA expression of DKK-3 and WIF-1 in hepatocellular carcinoma. World J Gastroenterol 2009; 15(21): 2595-2601 [PMID: 19496188 DOI: 10.3748/wjg.15.2595]
URL: https://www.wjgnet.com/1007-9327/full/v15/i21/2595.htm
Number Citing Articles
1
Babak Rahmani, Dariush Hamedi Asl, Taghi Naserpour Farivar, Mehdi Azad, Mehdi Sahmani, Nematollah Gheibi. Omega-3 PUFA Alters the Expression Level but Not the Methylation Pattern of the WIF1 Gene Promoter in a Pancreatic Cancer Cell Line (MIA PaCa-2)Biochemical Genetics 2019; 57(4) doi: 10.1007/s10528-018-9895-0
2
Jenifer R. Prosperi, Hue H. Luu, Kathleen H. Goss. Targeting the Wnt Pathway in Cancer2011;  doi: 10.1007/978-1-4419-8023-6_5
3
Anna Gajos-Michniewicz, Malgorzata Czyz. WNT/β-catenin signaling in hepatocellular carcinoma: The aberrant activation, pathogenic roles, and therapeutic opportunitiesGenes & Diseases 2024; 11(2) doi: 10.1016/j.gendis.2023.02.050
4
Tingxiu Xiang, Lili Li, Xuedong Yin, Lan Zhong, Weiyan Peng, Zhu Qiu, Guosheng Ren, Qian Tao. Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β‐catenin signalling and apoptosis regulation in breast cancer cellsJournal of Cellular and Molecular Medicine 2013; 17(10) doi: 10.1111/jcmm.12099
5
Shuang Zhao, Chang-lai Hao, En-hong Zhao, Hua-mao Jiang, Hua-chuan Zheng. The Suppressing Effects of Dkk3 Expression on Aggressiveness and Tumorigenesis of Colorectal CancerFrontiers in Oncology 2020; 10 doi: 10.3389/fonc.2020.600322
6
Xiaoyan Wang, Yun Zhou, Chunfu Wang, Yanyan Zhao, Yan Cheng, Suhuai Yu, Xiaofeng Li, Wenjing Zhang, Ying Zhang, Huiqin Quan. HCV Core protein represses DKK3 expression via epigenetic silencing and activates the Wnt/β-catenin signaling pathway during the progression of HCCClinical and Translational Oncology 2022; 24(10) doi: 10.1007/s12094-022-02859-y
7
Chun-Ming Tsao, Ming-De Yan, Yu-Lueng Shih, Pei-Ning Yu, Chih-Chi Kuo, Wen-Chi Lin, Hsin-Jung Li, Ya-Wen Lin. SOX1 functions as a tumor suppressor by antagonizing the WNT/β-catenin signaling pathway in hepatocellular carcinomaHepatology 2012; 56(6) doi: 10.1002/hep.25933
8
Floriane Pez, Anaïs Lopez, Miran Kim, Jack R. Wands, Claude Caron de Fromentel, Philippe Merle. Wnt signaling and hepatocarcinogenesis: Molecular targets for the development of innovative anticancer drugsJournal of Hepatology 2013; 59(5) doi: 10.1016/j.jhep.2013.07.001
9
Taj D. King, Wei Zhang, Mark J. Suto, Yonghe Li. Frizzled7 as an emerging target for cancer therapyCellular Signalling 2012; 24(4) doi: 10.1016/j.cellsig.2011.12.009
10
NAOKI KATASE, MATHIEU LEFEUVRE, HIDETSUGU TSUJIGIWA, MASAE FUJII, SATOSHI ITO, RYO TAMAMURA, ROSARIO RIVERA BUERY, MEHMET GUNDUZ, HITOSHI NAGATSUKA. Knockdown of Dkk-3 decreases cancer cell migration and invasion independently of the Wnt pathways in oral squamous cell carcinoma-derived cellsOncology Reports 2013; 29(4) doi: 10.3892/or.2013.2251
11
Mingzhou Guo, Yaojun Peng, Aiai Gao, Chen Du, James G. Herman. Epigenetic heterogeneity in cancerBiomarker Research 2019; 7(1) doi: 10.1186/s40364-019-0174-y
12
Thanh H. Dellinger, Kestutis Planutis, Danielle D. Jandial, Ramez N. Eskander, Micaela E. Martinez, Xiaolin Zi, Bradley J. Monk, Randall F. Holcombe. Expression of the Wnt antagonist Dickkopf-3 is associated with prognostic clinicopathologic characteristics and impairs proliferation and invasion in endometrial cancerGynecologic Oncology 2012; 126(2) doi: 10.1016/j.ygyno.2012.04.026
13
NAOKI KATASE, MATHIEU LEFEUVRE, MEHMET GUNDUZ, ESRA GUNDUZ, LEVENT BEKIR BEDER, REIDAR GRENMAN, MASAE FUJII, RYO TAMAMURA, HIDETSUGU TSUJIGIWA, HITOSHI NAGATSUKA. Absence of Dickkopf (Dkk)-3 protein expression is correlated with longer disease-free survival and lower incidence of metastasis in head and neck squamous cell carcinomaOncology Letters 2012; 3(2) doi: 10.3892/ol.2011.473
14
SHANGHUI ZHOU, LING CHEN, MUBARAK MASHRAH, YUN ZHU, ZHIJING HE, YUHUA HU, TINGXIU XIANG, ZHIGANG YAO, FENG GUO, CHENPING ZHANG. Expression and promoter methylation of Wnt inhibitory factor-1 in the development of oral submucous fibrosisOncology Reports 2015; 34(5) doi: 10.3892/or.2015.4264
15
Bjørn Helge Haug, Jørn R. Henriksen, Jochen Buechner, Dirk Geerts, Ellen Tømte, Per Kogner, Tommy Martinsson, Trond Flægstad, Baldur Sveinbjørnsson, Christer Einvik. MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastomaCarcinogenesis 2011; 32(7) doi: 10.1093/carcin/bgr073
16
Junxiong Cheng, Zhiwei Chen, Guoqing Zuo, Wenfu Cao. Integrated analysis of differentially expressed genes, differentially methylated genes, and natural compounds in hepatitis C virus-induced cirrhosisJournal of International Medical Research 2022; 50(1) doi: 10.1177/03000605221074525
17
Maedeh Mashhadikhan, Hamidreza Kheiri, Ali Dehghanifard. DNA methylation and gene expression of sFRP2, sFRP4, Dkk 1, and Wif1 during osteoblastic differentiation of bone marrow derived mesenchymal stem cellsJournal of Oral Biosciences 2020; 62(4) doi: 10.1016/j.job.2020.08.001
18
Dor Mohammad Kordi-Tamandani, Abdolkarim Moazeni-Roodi, Mohammad Ayoub Rigi Ladez, Mohammad Hashemi, Elnaz Birjandian, Adam Torkamanzehi. Analysis of Methylation Patterns and Expression Profiles of P14Arf Gene in Patients with Oral Squamous Cell CarcinomaThe International Journal of Biological Markers 2010; 25(2) doi: 10.1177/172460081002500207
19
Yassine Alami Idrissi, Mohammad Reza Rajabi, Jan H. Beumer, Satdarshan P. Monga, Anwaar Saeed. Exploring the Impact of the β-Catenin Mutations in Hepatocellular Carcinoma: An In-Depth ReviewCancer Control 2024; 31 doi: 10.1177/10732748241293680
20
Da-Hua Liu, Gui-Min Wen, Chang-Liang Song, Pu Xia. Effect of secretory DKK3 on circulating CD56bright natural killer cells in patients with liver cancerThe International Journal of Biological Markers 2023; 38(2) doi: 10.1177/03936155231169796
21
YI-PENG CHEN, XI JIN, MEI KONG, YOU-MING LI. Pattern of microRNA expression associated with different stages of alcoholic liver disease in rat modelsMolecular Medicine Reports 2014; 10(3) doi: 10.3892/mmr.2014.2368
22
CONG-JUN WANG, DE-KAI GUO, TIAN-GENG YOU, DONG-WEI SHEN, CHAO WANG, LIN TANG, JIAN WANG, RONG-HUA XU, HUI ZHANG. Inhibition of hepatocellular carcinoma by fulvestrant involves the estrogen receptor α and Wnt pathways in vitro and in patientsMolecular Medicine Reports 2014; 10(6) doi: 10.3892/mmr.2014.2595
23
Shibo Wang, Xincong Li, Hao Liu, Jiali Zhang, Jiaxi Li, Xu Jin, Chenjie Fang. Advances in Nanomedicine for Modulating DNA Methylation and Inducing PyroptosisJournal of Nanotheranostics 2026; 7(2) doi: 10.3390/jnt7020014
24
Jean-Pierre Roperch, Roberto Incitti, Solène Forbin, Floriane Bard, Hicham Mansour, Farida Mesli, Isabelle Baumgaertner, Francesco Brunetti, Iradj Sobhani. Aberrant methylation of NPY, PENK, and WIF1 as a promising marker for blood-based diagnosis of colorectal cancerBMC Cancer 2013; 13(1) doi: 10.1186/1471-2407-13-566
25
Zhuanyi Yang, Ying Wang, Jiasheng Fang, Fenghua Chen, Jinfang Liu, Jun Wu, Yanjin Wang. Expression and aberrant promoter methylation of Wnt inhibitory factor-1 in human astrocytomasJournal of Experimental & Clinical Cancer Research 2010; 29(1) doi: 10.1186/1756-9966-29-26
26
M R Emma, J L Iovanna, D Bachvarov, R Puleio, G R Loria, G Augello, S Candido, M Libra, A Gulino, V Cancila, J A McCubrey, G Montalto, M Cervello. NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistanceCell Death & Disease 2016; 7(6) doi: 10.1038/cddis.2016.175
27
Chunyi Ji, Lijian Chen, Miaoxian Yuan, Weixin Xie, Xinyi Sheng, Qiang Yin. KDM1A drives hepatoblastoma progression by activating the Wnt/β-catenin pathway through inhibition of DKK3 transcriptionTissue and Cell 2023; 81 doi: 10.1016/j.tice.2022.101989
28
Yan Guo, Zhidong Sun, Xiao Liu, Xianni Liu, Haiwen Chen, Menglan Zhang, Weibo Mao, Yuan Cao. TTK Overexpression: A Negative Prognostic Biomarker in Anaplastic Thyroid CarcinomaCancer Medicine 2026; 15(6) doi: 10.1002/cam4.71995
29
Sun A Kim, Jihye Kwak, Hae Yun Nam, Sung Min Chun, Byoung Wook Lee, Hyang Ju Lee, Shin Kwang Khang, Seong Who Kim. Promoter methylation of WNT inhibitory factor-1 and expression pattern of WNT/β-catenin pathway in human astrocytoma: pathologic and prognostic correlationsModern Pathology 2013; 26(5) doi: 10.1038/modpathol.2012.215
30
Xiao-yan Xu, Pu Xia, Miao Yu, Xiao-cui Nie, Xue Yang, Ya-nan Xing, Yun-peng Liu, Yasuo Takano, Hua-chuan Zheng. The roles of REIC gene and its encoding product in gastric carcinomaCell Cycle 2012; 11(7) doi: 10.4161/cc.19823
31
Ze-Guang Han. Functional Genomic Studies: Insights into the Pathogenesis of Liver CancerAnnual Review of Genomics and Human Genetics 2012; 13(1) doi: 10.1146/annurev-genom-090711-163752
32
Byul A Jee, Ji-Hye Choi, Hyungjin Rhee, Sarah Yoon, So Mee Kwon, Ji Hae Nahm, Jeong Eun Yoo, Youngsic Jeon, Gi Hong Choi, Hyun Goo Woo, Young Nyun Park. Dynamics of Genomic, Epigenomic, and Transcriptomic Aberrations during Stepwise HepatocarcinogenesisCancer Research 2019; 79(21) doi: 10.1158/0008-5472.CAN-19-0991
33
Rainbow Wing Hei Leung, Terence Kin Wah Lee. Wnt/β-Catenin Signaling as a Driver of Stemness and Metabolic Reprogramming in Hepatocellular CarcinomaCancers 2022; 14(21) doi: 10.3390/cancers14215468
34
Mohammad Reza Allahyar Torkaman, Kazunari Kamachi, Vajihe Sadat Nikbin, Masoumeh Nakhost Lotfi, Fereshteh Shahcheraghi. Comparison of loop-mediated isothermal amplification and real-time PCR for detecting Bordetella pertussis Journal of Medical Microbiology 2015; 64(4) doi: 10.1099/jmm.0.000021
35
Yong Zhou, Zhaohua Li, Yinlu Ding, Peng Zhang, Jinqing Wang, Jianliang Zhang, Hao Wang. Promoter methylation of WNT inhibitory factor-1 may be associated with the pathogenesis of multiple human tumorsJournal of Cancer Research and Therapeutics 2018; 14(Suppl 2) doi: 10.4103/0973-1482.235357
36
Kaveri Sidhu, Neetu Rohit Kapoor, Vijaya Pandey, Vijay Kumar. The “Macro” World of microRNAs in Hepatocellular CarcinomaFrontiers in Oncology 2015; 5 doi: 10.3389/fonc.2015.00068
37
Dan Lu, Wei Dong, Xu Zhang, Xiongzhi Quan, Dan Bao, Yingdong Lu, Lianfeng Zhang. WIF1 causes dysfunction of heart in transgenic miceTransgenic Research 2013; 22(6) doi: 10.1007/s11248-013-9738-z
38
Yue Li, Shou-Li Yuan, Jing-Ya Yin, Kun Yang, Xin-Gang Zhou, Wen Xie, Qi Wang. Differences of core genes in liver fibrosis and hepatocellular carcinoma: Evidence from integrated bioinformatics and immunohistochemical analysisWorld Journal of Gastrointestinal Oncology 2022; 14(7): 1265-1280 doi: 10.4251/wjgo.v14.i7.1265
39
Ioannis Anestopoulos, Georgia Persephoni Voulgaridou, Alexandros G. Georgakilas, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis. Epigenetic therapy as a novel approach in hepatocellular carcinomaPharmacology & Therapeutics 2015; 145 doi: 10.1016/j.pharmthera.2014.09.005
40
Hemn Mohammadpour, Reza Fekrazad. Antitumor effect of combined Dkk-3 and 5-ALA mediated photodynamic therapy in breast cancer cell’s colonyPhotodiagnosis and Photodynamic Therapy 2016; 14 doi: 10.1016/j.pdpdt.2016.04.001
41
Naoki Katase, Shin-Ichiro Nishimatsu, Akira Yamauchi, Masahiro Yamamura, Kumiko Terada, Masumi Itadani, Naoko Okada, Nur Mohammad Monsur Hassan, Hitoshi Nagatsuka, Tohru Ikeda, Tsutomu Nohno, Shuichi Fujita. DKK3 Overexpression Increases the Malignant Properties of Head and Neck Squamous Cell Carcinoma CellsOncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2018; 26(1) doi: 10.3727/096504017X14926874596386
42
Stefan David, Stephen J. Meltzer. Pre-Invasive Disease: Pathogenesis and Clinical Management2011;  doi: 10.1007/978-1-4419-6694-0_4
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Guan-Yu Chen, Hua-Chuan Zheng. The clinicopathological and prognostic significances of Dkk3 expression in cancers: A bioinformatics analysisCancer Biomarkers 2018; 23(3) doi: 10.3233/CBM-181245
44
Jürgen Veeck, Edgar Dahl. Targeting the Wnt pathway in cancer: The emerging role of Dickkopf-3Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2012; 1825(1) doi: 10.1016/j.bbcan.2011.09.003
45
Michael Medinger, Patricia Muesser, Sabine Girsberger, Radek Skoda, Alexandar Tzankov, Andreas Buser, Jakob Passweg, Dimitrios Α. Tsakiris. Dkk3 levels in patients with myeloproliferative neoplasmsThrombosis Research 2014; 133(2) doi: 10.1016/j.thromres.2013.11.003
46
Naoki Katase, Kenichi Nagano, Shuichi Fujita. DKK3 expression and function in head and neck squamous cell carcinoma and other cancersJournal of Oral Biosciences 2020; 62(1) doi: 10.1016/j.job.2020.01.008
47
S Fatima, N P Lee, F H Tsang, F T Kolligs, I O L Ng, R T P Poon, S T Fan, J M Luk. Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway by influencing β-catenin in hepatocellular carcinomaOncogene 2012; 31(38) doi: 10.1038/onc.2011.580
48
Ren-xiang Liu, Guo-liang Zheng, Ning Li, Zheng-guo Cui, Hua-chuan Zheng. Dkk3 inhibits the aggressiveness and mitigates chemoresistance through low lipid droplet formation in gastric cancer: A biomarker and gene therapy targetInternational Immunopharmacology 2025; 149 doi: 10.1016/j.intimp.2025.114200
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Naoshi Nishida, Hirokazu Chishina, Tadaaki Arizumi, Masahiro Takita, Satoshi Kitai, Norihisa Yada, Satoru Hagiwara, Tatsuo Inoue, Yasunori Minami, Kazuomi Ueshima, Toshiharu Sakurai, Masatoshi Kudo. Identification of Epigenetically Inactivated Genes in Human Hepatocellular Carcinoma by Integrative Analyses of Methylation Profiling and Pharmacological UnmaskingDigestive Diseases 2014; 32(6) doi: 10.1159/000368015
50
Bin Lin, HaiJie Hong, XiaoJie Jiang, ChengZong Li, SiYuan Zhu, NanHong Tang, XiaoQian Wang, FeiFei She, YanLing Chen. WNT inhibitory factor 1 promoter hypermethylation is an early event during gallbladder cancer tumorigenesis that predicts poor survivalGene 2017; 622 doi: 10.1016/j.gene.2017.04.034
51
Claire Medine, Janet Kung, Catherine Payne, James Black, Richard Anderson, James Ross, John Iredale. Regenerative Medicine, Stem Cells and the Liver2012;  doi: 10.1201/b11937-5
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Leon J Wils, Maarten F Bijlsma. Epigenetic regulation of the Hedgehog and Wnt pathways in cancerCritical Reviews in Oncology/Hematology 2018; 121 doi: 10.1016/j.critrevonc.2017.11.013
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Yiping Qu, Siwen Dang, Peng Hou. Gene methylation in gastric cancerClinica Chimica Acta 2013; 424 doi: 10.1016/j.cca.2013.05.002
54
Fan Zhu, Chuan-Jie Zhang, Jing-Ling Xue, Ya-Tang Chen, Shui-Xiang Xie, Li-Juan Liu. Aberrant regulation of Wnt signaling in hepatocellular carcinomaWorld Journal of Gastroenterology 2016; 22(33): 7486-7499 doi: 10.3748/wjg.v22.i33.7486
55
Cosmina Fugărețu, Valeriu Șurlin, Catalin Misarca, Ana-Maria Ciurea, Stefan Patrascu, Dumitru Sandu Ramboiu, Mihail Virgil Boldeanu, Adina Turcu-Stiolica, Stiliani Laskou, Cicerone Catalin Grigorescu. Evaluation of the Clinical Value of the Serological Markers CD276 and DKK3 in Gastric Cancer: A Case–Control StudyDiagnostics 2026; 16(6) doi: 10.3390/diagnostics16060840