| For: | Cui W, Gu F, Hu KQ. Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice. World J Gastroenterol 2009; 15(16): 1943-1950 [PMID: 19399925 DOI: 10.3748/wjg.15.1943] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v15/i16/1943.htm |
| Number | Citing Articles |
| 1 |
Mark F. McCarty, Jorge Barroso-Aranda, Francisco Contreras. Practical strategies for suppressing hypoxia-inducible factor activity in cancer therapy. Medical Hypotheses 2010; 74(5) doi: 10.1016/j.mehy.2009.12.022
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| 2 |
Farah Abid, Muhammad Saleem, Saleha Yasir, Shumila Arshad, Sundus Qureshi, Mayyda Asif Bajwa, Sana Ashiq, Samreen Tanveer, Mehiwh Qayyum, Kanwal Ashiq. CANCER EPIGENETICS AND THE ROLE OF DIETARY ELEMENTS. Gomal Journal of Medical Sciences 2020; 17(3) doi: 10.46903/gjms/17.03.2070
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| 3 |
P. K. Praveen Kumar, Harini Sundar, Kamalavarshini Balakrishnan, Sakthivel Subramaniam, Hemalatha Ramachandran, M. Kevin, M. Michael Gromiha. The Role of HSP90 and TRAP1 Targets on Treatment in Hepatocellular Carcinoma. Molecular Biotechnology 2025; 67(4) doi: 10.1007/s12033-024-01151-4
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| 4 |
Chen-Yi Liao, Ching-Chang Lee, Chi-chang Tsai, Chao-Wen Hsueh, Chih-Chiang Wang, I-Hung Chen, Ming-Kai Tsai, Mei-Yu Liu, An-Tie Hsieh, Kuan-Jen Su, Hau-Ming Wu, Shih-Chung Huang, Yi-Chen Wang, Chien-Yao Wang, Shu-Fang Huang, Yen-Cheng Yeh, Ren-Jy Ben, Shang-Tao Chien, Chin-Wen Hsu, Wu-Hsien Kuo. Novel Investigations of Flavonoids as Chemopreventive Agents for Hepatocellular Carcinoma. BioMed Research International 2015; 2015 doi: 10.1155/2015/840542
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| 5 |
Birgit M. Dietz, Atieh Hajirahimkhan, Tareisha L. Dunlap, Judy L. Bolton. Botanicals and Their Bioactive Phytochemicals for Women’s Health. Pharmacological Reviews 2016; 68(4) doi: 10.1124/pr.115.010843
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| 6 |
Daiane Teixeira de Oliveira, André Luiz Ventura Sávio, João Paulo de Castro Marcondes, Tatiane Martins Barros, Ludmila Correia Barbosa, Daisy Maria Favero Salvadori, Glenda Nicioli da Silva. Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status. Journal of Biosciences 2017; 42(1) doi: 10.1007/s12038-016-9654-5
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| 7 |
Fabiana Vento, Anna Privitera, Giuseppe Caruso, Angelo Nicosia. A Silibinin‐Poly(ε‐Caprolactone) Conjugate as an Enhanced Anticancer Agent. Macromolecular Bioscience 2025; 25(4) doi: 10.1002/mabi.202400510
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| 8 |
Davood Mohammadi, Amir Hossein Aghayan, Diba Mohammadi, Mohammad Jahanbakhsh Mashhadi, Zahra Jamalpoor, Abbas Rahdar, Sadanand Pandey. Therapeutic Effects of Silibinin on Animal Models of Skin Cancer: A Systematic Review and Meta-Analysis. BioNanoScience 2025; 15(3) doi: 10.1007/s12668-025-02025-y
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| 9 |
. 2019; doi: 10.70675/50131371z9cf2z4925zad84ze1758a9a5831
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| 10 |
June K. Dunnick, Bhanu Singh, Abraham Nyska, John Peckham, Grace E. Kissling, J. Michael Sanders. Investigating the Potential for Toxicity from Long-Term Use of the Herbal Products, Goldenseal and Milk Thistle. Toxicologic Pathology 2011; 39(2) doi: 10.1177/0192623310394211
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| 11 |
Gopika Chandrababu, Merlin Varkey, Aswathy R. Devan, M. V. Anjaly, Ashok R. Unni, Lekshmi R. Nath. Kaempferide exhibits an anticancer effect against hepatocellular carcinoma in vitro and in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology 2023; 396(10) doi: 10.1007/s00210-023-02468-8
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| 12 |
Run-Ze Shang, Shi-Bin Qu, De-Sheng Wang. Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects. World Journal of Gastroenterology 2016; 22(45): 9933-9943 doi: 10.3748/wjg.v22.i45.9933
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| 13 |
Wen-Shiung Liou, Li-Jen Chen, Ho-Shan Niu, Ting-Ting Yang, Juei-Tang Cheng, Kao-Chang Lin. Herbal product silibinin-induced programmed cell death is enhanced by metformin in cervical cancer cells at the dose without influence on nonmalignant cells. Journal of Applied Biomedicine 2015; 13(2) doi: 10.1016/j.jab.2014.11.001
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| 14 |
Estefanny Ruiz García, Eliana Alviárez Gutierrez, Fabiana Cristina Silveira Alves de Melo, Rômulo Dias Novaes, Reggiani Vilela Gonçalves, Célia Cabral. Flavonoids Effects on Hepatocellular Carcinoma in Murine Models: A Systematic Review. Evidence-Based Complementary and Alternative Medicine 2018; 2018(1) doi: 10.1155/2018/6328970
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| 15 |
Gagan Deep, Rajesh Agarwal. Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer. Cancer and Metastasis Reviews 2010; 29(3) doi: 10.1007/s10555-010-9237-0
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| 16 |
Pantha Prodip Ray, Mohammad Ashraful Islam, Mohammad Safiqul Islam, Aixia Han, Peiwu Geng, Md. Abdul Aziz, Abdullah Al Mamun. A comprehensive evaluation of the therapeutic potential of silibinin: a ray of hope in cancer treatment. Frontiers in Pharmacology 2024; 15 doi: 10.3389/fphar.2024.1349745
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| 17 |
Yizeng Fan, Tao Hou, Weichao Dan, Tianjie Liu, Jiaxin Luan, Bo Liu, Lei Li, Jin Zeng. Silibinin inhibits epithelial‑mesenchymal transition of renal cell carcinoma through autophagy‑dependent Wnt/β‑catenin signaling. International Journal of Molecular Medicine 2020; doi: 10.3892/ijmm.2020.4521
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| 18 |
G.B. Maru, G. Kumar, S. Ghantasala, P. Tajpara. Polyphenols in Human Health and Disease. 2014; doi: 10.1016/B978-0-12-398456-2.00088-8
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| 19 |
Agnieszka Zaczek, Aleksandra Rodacka. Investigating the Epigenetic Therapeutic Potential of Natural Compounds in Cancer. International Journal of Molecular Sciences 2025; 26(21) doi: 10.3390/ijms262110776
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| 20 |
Tianhao Sun, Kelvin S. C. Cheung, Zhi‐Li Liu, Frankie Leung, William W. Lu. Matrix metallopeptidase 9 targeted by hsa‐miR‐494 promotes silybin‐inhibited osteosarcoma. Molecular Carcinogenesis 2018; 57(2) doi: 10.1002/mc.22753
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| 21 |
Reza Ghasemi, Seyed H. Ghaffari, Majid Momeny, Saeed Pirouzpanah, Mehdi Yousefi, Mohsen Malehmir, Kamran Alimoghaddam, Ardeshir Ghavamzadeh. Multitargeting and Antimetastatic Potentials of Silibinin in Human HepG-2 and PLC/PRF/5 Hepatoma Cells. Nutrition and Cancer 2013; 65(4) doi: 10.1080/01635581.2013.770043
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| 22 |
Yangyang Hu, Shengpeng Wang, Xu Wu, Jinming Zhang, Ruie Chen, Meiwan Chen, Yitao Wang. Chinese herbal medicine-derived compounds for cancer therapy: A focus on hepatocellular carcinoma. Journal of Ethnopharmacology 2013; 149(3) doi: 10.1016/j.jep.2013.07.030
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| 23 |
Chang Eun Park, Hee Yun, Eun-Byul Lee, Byung-Il Min, Hyunsu Bae, Wonchae Choe, Insug Kang, Sung-Soo Kim, Joohun Ha. The Antioxidant Effects of Genistein Are Associated with AMP-Activated Protein Kinase Activation and PTEN Induction in Prostate Cancer Cells. Journal of Medicinal Food 2010; 13(4) doi: 10.1089/jmf.2009.1359
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| 24 |
Harold Ting, Gagan Deep, Rajesh Agarwal. Molecular Mechanisms of Silibinin-Mediated Cancer Chemoprevention with Major Emphasis on Prostate Cancer. The AAPS Journal 2013; 15(3) doi: 10.1208/s12248-013-9486-2
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| 25 |
Ioannis Anestopoulos, Anthula Kavo, Ioannis Tentes, Alexandros Kortsaris, Mihalis Panayiotidis, Antigone Lazou, Aglaia Pappa. Silibinin protects H9c2 cardiac cells from oxidative stress and inhibits phenylephrine-induced hypertrophy: potential mechanisms. The Journal of Nutritional Biochemistry 2013; 24(3) doi: 10.1016/j.jnutbio.2012.02.009
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| 26 |
Michael Schnekenburger, Mario Dicato, Marc Diederich. Plant-derived epigenetic modulators for cancer treatment and prevention. Biotechnology Advances 2014; 32(6) doi: 10.1016/j.biotechadv.2014.03.009
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| 27 |
Anupam Bishayee. Inflammation and Cancer. Advances in Experimental Medicine and Biology 2014; 816 doi: 10.1007/978-3-0348-0837-8_16
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| 28 |
Chin-Hui Su, Li-Jen Chen, Jyh Fei Liao, Juei-Tang Cheng. Increase of Phosphatase and Tensin Homolog by Silymarin to Inhibit Human Pharynx Squamous Cancer. Journal of Medicinal Food 2013; 16(9) doi: 10.1089/jmf.2012.2534
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| 29 |
Lei Li, Jin Zeng, Ye Gao, Dalin He. Targeting silibinin in the antiproliferative pathway. Expert Opinion on Investigational Drugs 2010; 19(2) doi: 10.1517/13543780903533631
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| 30 |
Yuening Xiang, Zimu Guo, Pengfei Zhu, Jia Chen, Yongye Huang. Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science. Cancer Medicine 2019; 8(5) doi: 10.1002/cam4.2108
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| 31 |
Wen Tan, Jinjian Lu, Mingqing Huang, Yingbo Li, Meiwan Chen, Guosheng Wu, Jian Gong, Zhangfeng Zhong, Zengtao Xu, Yuanye Dang, Jiajie Guo, Xiuping Chen, Yitao Wang. Anti-cancer natural products isolated from chinese medicinal herbs. Chinese Medicine 2011; 6(1) doi: 10.1186/1749-8546-6-27
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| 32 |
Ioannis Anestopoulos, Georgia Persephoni Voulgaridou, Alexandros G. Georgakilas, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis. Epigenetic therapy as a novel approach in hepatocellular carcinoma. Pharmacology & Therapeutics 2015; 145 doi: 10.1016/j.pharmthera.2014.09.005
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| 33 |
Eshita Sharma, Manju Tewari, Priyanka Sati, Isha Sharma, Dharam Chand Attri, Supriyanka Rana, Afaf Ahmed Aldahish, Daniela Calina, Praveen Dhyani, Javad Sharifi‐Rad, William C. Cho. Serving up health: How phytochemicals transform food into medicine in the battle against cancer. Food Frontiers 2024; 5(5) doi: 10.1002/fft2.439
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| 34 |
Christian Busch, Markus Burkard, Christian Leischner, Ulrich M. Lauer, Jan Frank, Sascha Venturelli. Epigenetic activities of flavonoids in the prevention and treatment of cancer. Clinical Epigenetics 2015; 7(1) doi: 10.1186/s13148-015-0095-z
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| 35 |
Xing-Xing Zhu, Ya-Hui Ding, Yi Wu, Lin-Yan Qian, Hai Zou, Qiang He. Silibinin: a potential old drug for cancer therapy. Expert Review of Clinical Pharmacology 2016; 9(10) doi: 10.1080/17512433.2016.1208563
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| 36 |
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| 37 |
Cheng-Chia Tsai, Tang-Wei Chuang, Li-Jen Chen, Ho-Shan Niu, Kun-Ming Chung, Juei-Tang Cheng, Kao-Chang Lin. Increase in apoptosis by combination of metformin with silibinin in human colorectal cancer cells. World Journal of Gastroenterology 2015; 21(14): 4169-4177 doi: 10.3748/wjg.v21.i14.4169
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| 38 |
Hann‐Chin Yu, Li‐Jen Chen, Kai‐Chun Cheng, Ying‐Xiao Li, Ching‐Hua Yeh, Juei‐Tang Cheng. Silymarin Inhibits Cervical Cancer Cell Through an Increase of Phosphatase and Tensin Homolog. Phytotherapy Research 2012; 26(5) doi: 10.1002/ptr.3618
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| 39 |
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| 40 |
Cheng Chi, Chenshuang Zhang, Yang Liu, Haichen Nie, Jianping Zhou, Yang Ding. Phytosome-nanosuspensions for silybin-phospholipid complex with increased bioavailability and hepatoprotection efficacy. European Journal of Pharmaceutical Sciences 2020; 144 doi: 10.1016/j.ejps.2020.105212
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| 41 |
Hua Sun, Linghong Yu, Huailing Wei, Gengtao Liu. A Novel Antihepatitis Drug, Bicyclol, Prevents Liver Carcinogenesis in Diethylnitrosamine-Initiated and Phenobarbital-Promoted Mice Tumor Model. Journal of Biomedicine and Biotechnology 2012; 2012 doi: 10.1155/2012/584728
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| 42 |
Dimitrios Stagos, Gregorios D. Amoutzias, Antonios Matakos, Argyris Spyrou, Aristides M. Tsatsakis, Dimitrios Kouretas. Chemoprevention of liver cancer by plant polyphenols. Food and Chemical Toxicology 2012; 50(6) doi: 10.1016/j.fct.2012.04.002
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| 43 |
Ioannis Anestopoulos, Aristeidis Sfakianos, Rodrigo Franco, Katerina Chlichlia, Mihalis Panayiotidis, David Kroll, Aglaia Pappa. A Novel Role of Silibinin as a Putative Epigenetic Modulator in Human Prostate Carcinoma. Molecules 2016; 22(1) doi: 10.3390/molecules22010062
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| 44 |
Thae Hyun Kim, Jae Suk Woo, Yong Keun Kim, Ki Hyung Kim. Silibinin Induces Cell Death through Reactive Oxygen Species–Dependent Downregulation of Notch-1/ERK/Akt Signaling in Human Breast Cancer Cells. The Journal of Pharmacology and Experimental Therapeutics 2014; 349(2) doi: 10.1124/jpet.113.207563
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| 45 |
Tomas Koltai, Stephan J. Reshkin, Salvador Harguindey. An Innovative Approach to Understanding and Treating Cancer: Targeting pH. 2020; doi: 10.1016/B978-0-12-819059-3.00015-0
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| 46 |
Xiaohong Yan, Thomas R. Gardner, Michael Grieco, Sonali A. C. Herath, Joon Ho Jang, Daniel Kirchoff, Linda Njoh, H. M. C. Shantha Kumara, Samer Naffouje, Richard L. Whelan. Perioperative polyphenon E- and siliphos-inhibited colorectal tumor growth and metastases without impairment of gastric or abdominal wound healing in mouse models. Surgical Endoscopy 2012; 26(7) doi: 10.1007/s00464-011-2114-2
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| 47 |
Jeanetta K. Mastron, Kodappully S. Siveen, Gautam Sethi, Anupam Bishayee. Silymarin and hepatocellular carcinoma. Anti-Cancer Drugs 2015; 26(5) doi: 10.1097/CAD.0000000000000211
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| 48 |
Lin-bo Zhang, Lei Qiang, Fei-hong Chen, Tian Wu, Jing-jing Rong, Qing Zhao, Mei-juan Zou, Zhen Yang, Qi-dong You, Zhi-yu Li, Yu-lin Wu, Qing-long Guo. DHF-18, a new synthetic flavonoid, induced a mitochondrial-mediated apoptosis of hepatocarcinoma cells in vivo and in vitro. European Journal of Pharmacology 2011; 651(1-3) doi: 10.1016/j.ejphar.2010.10.067
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| 49 |
Travis L. Schmit, Mark C. Ledesma, Nihal Ahmad. Modulating Polo-Like Kinase 1 as a Means for Cancer Chemoprevention. Pharmaceutical Research 2010; 27(6) doi: 10.1007/s11095-010-0051-8
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| 50 |
Fadime Eryılmaz Pehlivan. Epigenetics to Optogenetics - A New Paradigm in the Study of Biology. Biochemistry 2022; 35 doi: 10.5772/intechopen.95374
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| 51 |
HENRIETTE KAUNTZ, SOUAD BOUSSEROUEL, FRANCINE GOSSÉ, FRANCIS RAUL. Epigenetic effects of the natural flavonolignan silibinin on colon adenocarcinoma cells and their derived metastatic cells. Oncology Letters 2013; 5(4) doi: 10.3892/ol.2013.1190
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| 52 |
Tomas Koltai, Larry Fliegel. Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions. Journal of Evidence-Based Integrative Medicine 2022; 27 doi: 10.1177/2515690X211068826
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| 53 |
Nihal M. Elguindy, Galila A. Yacout, Eman F. El Azab, Hala K. Maghraby. Chemoprotective Effect of Elettaria Cardamomum against Chemically induced Hepatocellular Carcinoma in Rats by Inhibiting NF-κB, Oxidative Stress, and Activity of Ornithine Decarboxylase. South African Journal of Botany 2016; 105 doi: 10.1016/j.sajb.2016.04.001
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| 54 |
. 2012; doi: 10.70675/45aa02d4zd1a8z4db3z8a59zdbdbbc1ed4fc
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