For: | Liu HY, Huang ZL, Yang GH, Lu WQ, Yu NR. Inhibitory effect of modified citrus pectin on liver metastases in a mouse colon cancer model. World J Gastroenterol 2008; 14(48): 7386-7391 [PMID: 19109874 DOI: 10.3748/wjg.14.7386] |
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URL: | https://www.wjgnet.com/1007-9327/full/v14/i48/7386.htm |
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Wenbo Zhang, Ping Xu, Han Zhang. Pectin in cancer therapy: A review. Trends in Food Science & Technology 2015; 44(2): 258 doi: 10.1016/j.tifs.2015.04.001
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Viviana Vergaro, Paride Papadia, Paola Petrini, Francesco Paolo Fanizzi, Sandra A. De Pascali, Francesca Baldassarre, Laura Pastorino, Giuseppe Ciccarella. Nanostructured polysaccharidic microcapsules for intracellular release of cisplatin. International Journal of Biological Macromolecules 2017; 99: 187 doi: 10.1016/j.ijbiomac.2017.02.066
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PectaSol-C Modified Citrus Pectin Induces Apoptosis and Inhibition of Proliferation in Human and Mouse Androgen-Dependent and- Independent Prostate Cancer Cells. Integrative Cancer Therapies 2010; 9(2): 197 doi: 10.1177/1534735410369672
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Ellen G. Maxwell, Nigel J. Belshaw, Keith W. Waldron, Victor J. Morris. Pectin – An emerging new bioactive food polysaccharide. Trends in Food Science & Technology 2012; 24(2): 64 doi: 10.1016/j.tifs.2011.11.002
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Wei Kang Cheng, Chern Ein Oon. How glycosylation aids tumor angiogenesis: An updated review. Biomedicine & Pharmacotherapy 2018; 103: 1246 doi: 10.1016/j.biopha.2018.04.119
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A. C. MacKinnon, X. Liu, P. W. Hadoke, M. R. Miller, D. E. Newby, T. Sethi. Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice. Glycobiology 2013; 23(6): 654 doi: 10.1093/glycob/cwt006
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Jin-Kyung Kim, Eun Kyung Shin, Jun Hong Park, Yoon Hee Kim, Jung Han Yoon Park. Antitumor and antimetastatic effects of licochalcone A in mouse models. Journal of Molecular Medicine 2010; 88(8): 829 doi: 10.1007/s00109-010-0625-2
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Zexu Dang, Alison MacKinnon, Lorna P. Marson, Tariq Sethi. Tubular Atrophy and Interstitial Fibrosis After Renal Transplantation Is Dependent on Galectin-3. Transplantation 2012; 93(5): 477 doi: 10.1097/TP.0b013e318242f40a
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Laurent Calvier, Maria Miana, Pascal Reboul, Victoria Cachofeiro, Ernesto Martinez-Martinez, Rudolf A. de Boer, Françoise Poirier, Patrick Lacolley, Faiez Zannad, Patrick Rossignol, Natalia López-Andrés. Galectin-3 Mediates Aldosterone-Induced Vascular Fibrosis. Arteriosclerosis, Thrombosis, and Vascular Biology 2013; 33(1): 67 doi: 10.1161/ATVBAHA.112.300569
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Derong Lin, Yi Ma, Wen Qin, Douglas A. Loy, Hong Chen, Qing Zhang. The structure, properties and potential probiotic properties of starch-pectin blend: A review. Food Hydrocolloids 2022; 129: 107644 doi: 10.1016/j.foodhyd.2022.107644
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Xiaoming Huang, Yifeng Zou, Lei Lian, Xiaojian Wu, Xiaosheng He, Xiaowen He, Xianrui Wu, Yan Huang, Ping Lan. Changes of T Cells and Cytokines TGF-β1 and IL-10 in Mice During Liver Metastasis of Colon Carcinoma: Implications for Liver Anti-tumor Immunity. Journal of Gastrointestinal Surgery 2013; 17(7): 1283 doi: 10.1007/s11605-013-2194-5
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Lei Wang, Lin Zhao, Fu-lian Gong, Chao Sun, Dan-dan Du, Xiao-xia Yang, Xiu-li Guo. Modified citrus pectin inhibits breast cancer development in mice by targeting tumor-associated macrophage survival and polarization in hypoxic microenvironment. Acta Pharmacologica Sinica 2022; 43(6): 1556 doi: 10.1038/s41401-021-00748-8
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14 |
Roy Heusschen, Arjan W. Griffioen, Victor L. Thijssen. Galectin-9 in tumor biology: A jack of multiple trades. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2013; 1836(1): 177 doi: 10.1016/j.bbcan.2013.04.006
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O.K. Sasina Sai, Usha K. Aravind, Charuvila T. Aravindakumar. Biomaterials in Microencapsulation. 2024; doi: 10.5772/intechopen.1004742
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Cheppail Ramachandran, Barry J Wilk, Arland Hotchkiss, Hoa Chau, Isaac Eliaz, Steven J Melnick. Activation of Human T-Helper/Inducer Cell, T-Cytotoxic Cell, B-Cell, and Natural Killer (NK)-Cells and induction of Natural Killer Cell Activity against K562 Chronic Myeloid Leukemia Cells with Modified Citrus Pectin. BMC Complementary and Alternative Medicine 2011; 11(1) doi: 10.1186/1472-6882-11-59
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James V. Michael, Lawrence E. Goldfinger. Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting. Seminars in Cancer Biology 2019; 54: 121 doi: 10.1016/j.semcancer.2017.11.021
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Wanchao Hu, Anne-Marie Cassard, Dragos Ciocan. Pectin in Metabolic Liver Disease. Nutrients 2022; 15(1): 157 doi: 10.3390/nu15010157
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Cheppail Ramachandran, Barry Wilk, Steven J. Melnick, Isaac Eliaz, Youn C. Kim. Synergistic Antioxidant and Anti‐Inflammatory Effects between Modified Citrus Pectin and Honokiol. Evidence-Based Complementary and Alternative Medicine 2017; 2017(1) doi: 10.1155/2017/8379843
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Jian-Xia Xu, Wei Xiong, Zhen Zeng, Yi Tang, Ya-Lan Wang, Ming Xiao, Ming Li, Qing Shu Li, Guang-Lin Song, Jing Kuang. Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in vivo. Molecular Medicine Reports 2017; 15(3): 1222 doi: 10.3892/mmr.2017.6152
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Wioleta Wojtasik, Magdalena Czemplik, Marta Preisner, Lucyna Dymińska, Guo Yuan, Jan Szopa, Anna Kulma. Pectin from transgenic flax shives regulates extracellular matrix remodelling in human skin fibroblasts. Process Biochemistry 2017; 55: 187 doi: 10.1016/j.procbio.2017.02.001
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22 |
Anna Plewa, Wiktor Niemiec, Joanna Filipowska, Anna M. Osyczka, Radosław Lach, Krzysztof Szczubiałka, Maria Nowakowska. Photocrosslinkable diazoresin/pectin films – Synthesis and application as cell culture supports. European Polymer Journal 2011; 47(8): 1503 doi: 10.1016/j.eurpolymj.2011.06.002
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April L. Darrow, Ralph V. Shohet, J. Gregory Maresh. Transcriptional analysis of the endothelial response to diabetes reveals a role for galectin-3. Physiological Genomics 2011; 43(20): 1144 doi: 10.1152/physiolgenomics.00035.2011
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Aizhen Zong, Hongzhi Cao, Fengshan Wang. Anticancer polysaccharides from natural resources: A review of recent research. Carbohydrate Polymers 2012; 90(4): 1395 doi: 10.1016/j.carbpol.2012.07.026
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Lawrence E. Goldfinger, James V. Michael. Regulation of Ras signaling and function by plasma membrane microdomains. BioScience Trends 2017; 11(1): 23 doi: 10.5582/bst.2016.01220
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Keita Ishisono, Tomio Yabe, Kohji Kitaguchi. Citrus pectin attenuates endotoxin shock via suppression of Toll-like receptor signaling in Peyer's patch myeloid cells. The Journal of Nutritional Biochemistry 2017; 50: 38 doi: 10.1016/j.jnutbio.2017.07.016
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27 |
Andrea Cedillo Ornelas, Sam Ferguson, Maya DePlaza, Tkai Adekunle, Riyaz Basha.
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28 |
Yuri L. Dorokhov, Tatiana V. Komarova, Igor V. Petrunia, Vyacheslav S. Kosorukov, Roman A. Zinovkin, Anastasia V. Shindyapina, Olga Y. Frolova, Yuri Y. Gleba, Joseph Najbauer. Methanol May Function as a Cross-Kingdom Signal. PLoS ONE 2012; 7(4): e36122 doi: 10.1371/journal.pone.0036122
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29 |
Natalia Zakharova, Kamila Kydralieva, Elnura Khudaibergenova, Nina Gorbunova, Svetlana Pomogailo, Gulzhian I. Dzhardimalieva, Anatoly Pomogailo, Sharipa Jorobekova. Synthesis and Characterization of Nanosized Pectin‐Based Formulations. Macromolecular Symposia 2012; (1): 175 doi: 10.1002/masy.201100126
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30 |
Ernesto Martinez-Martinez, Jaime Ibarrola, Laurent Calvier, Amaya Fernandez-Celis, Celine Leroy, Victoria Cachofeiro, Patrick Rossignol, Natalia Lopez-Andres, Philippe Rouet. Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage. PLOS ONE 2016; 11(11): e0166272 doi: 10.1371/journal.pone.0166272
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31 |
Shiguo Chen, Junhui Li, Shan Li, Lufeng Yan, Donghong Liu. Phytochemicals in Citrus. Functional Foods and Nutraceuticals 2017; : 133 doi: 10.1201/9781315369068-5
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Shikai Zhang, Geoffrey I. N. Waterhouse, Fangzhou Xu, Ziyang He, Yuyi Du, Yujing Lian, Peng Wu, Dongxiao Sun-Waterhouse. Recent advances in utilization of pectins in biomedical applications: a review focusing on molecular structure-directing health-promoting properties. Critical Reviews in Food Science and Nutrition 2023; 63(19): 3386 doi: 10.1080/10408398.2021.1988897
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Victor J. Morris, Nigel J. Belshaw, Keith W. Waldron, Ellen G. Maxwell. The bioactivity of modified pectin fragments. Bioactive Carbohydrates and Dietary Fibre 2013; 1(1): 21 doi: 10.1016/j.bcdf.2013.02.001
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35 |
Mohammed Hussein M. Alsharbaty, Ghassan A. Naji, Sameh S. Ali. Exploring the Synergistic Potential of Pectin-Chitosan Composites for Advanced Drug Delivery and Biomedical Implant Applications: A Comprehensive Review and Future Perspectives. F1000Research 2024; 13: 209 doi: 10.12688/f1000research.145101.2
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36 |
Camilo G. Sotomayor, Charlotte A. te Velde-Keyzer, Arjan Diepstra, Marco van Londen, Robert A. Pol, Adrian Post, Rijk O.B. Gans, Ilja M. Nolte, Riemer H.J.A. Slart, Martin H. de Borst, Stefan P. Berger, Ramón Rodrigo, Gerjan J. Navis, Rudolf A. de Boer, Stephan J.L. Bakker. Galectin-3 and Risk of Late Graft Failure in Kidney Transplant Recipients: A 10-year Prospective Cohort Study. Transplantation 2021; 105(5): 1106 doi: 10.1097/TP.0000000000003359
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Zhiliang Huang, Zenan Ai, Nan Li, Haofeng Xi, Xucan Gao, Feng Wang, Xiaojun Tan, Haiying Liu. Over expression of galectin-3 associates with short-term poor prognosis in stage II colon cancer. Cancer Biomarkers 2017; 17(4): 445 doi: 10.3233/CBM-160661
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Snigdha Satabdi Dixit, L. Muruganandam, I. Ganesh Moorthy. Pectin from fruit peel: A comprehensive review on various extraction approaches and their potential applications in pharmaceutical and food industries. Carbohydrate Polymer Technologies and Applications 2025; 9: 100708 doi: 10.1016/j.carpta.2025.100708
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Anna Aureli, Manuela Del Cornò, Beatrice Marziani, Sandra Gessani, Lucia Conti. Highlights on the Role of Galectin-3 in Colorectal Cancer and the Preventive/Therapeutic Potential of Food-Derived Inhibitors. Cancers 2022; 15(1): 52 doi: 10.3390/cancers15010052
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Helen Blanchard, Khuchtumur Bum-Erdene, Matthew W. Hugo. Inhibitors of Galectins and Implications for Structure-Based Design of Galectin-Specific Therapeutics. Australian Journal of Chemistry 2014; 67(12): 1763 doi: 10.1071/CH14362
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Alejandra Bermúdez-Oria, Guillermo Rodríguez-Gutiérrez, Manuel Alaiz, Javier Vioque, Julio Girón-Calle, Juan Fernández-Bolaños. Polyphenols associated to pectic polysaccharides account for most of the antiproliferative and antioxidant activities in olive extracts. Journal of Functional Foods 2019; 62: 103530 doi: 10.1016/j.jff.2019.103530
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Miao Hao, Xiaowen Yuan, Hairong Cheng, Huiting Xue, Tao Zhang, Yifa Zhou, Guihua Tai. Comparative studies on the anti-tumor activities of high temperature- and pH-modified citrus pectins. Food & Function 2013; 4(6): 960 doi: 10.1039/c3fo30350k
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48 |
Claudia Lara-Espinoza, Elizabeth Carvajal-Millán, René Balandrán-Quintana, Yolanda López-Franco, Agustín Rascón-Chu. Pectin and Pectin-Based Composite Materials: Beyond Food Texture. Molecules 2018; 23(4): 942 doi: 10.3390/molecules23040942
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Randa Ismail, Heba A. Habib, Aliaa F. Anter, Amr Amin, Gehan H. Heeba. Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways. Frontiers in Pharmacology 2025; 16 doi: 10.3389/fphar.2025.1528978
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50 |
Ellen G. Maxwell, Ian J. Colquhoun, Hoa K. Chau, Arland T. Hotchkiss, Keith W. Waldron, Victor J. Morris, Nigel J. Belshaw. Modified sugar beet pectin induces apoptosis of colon cancer cells via an interaction with the neutral sugar side-chains. Carbohydrate Polymers 2016; 136: 923 doi: 10.1016/j.carbpol.2015.09.063
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Lionel Leclere, Maude Fransolet, Francois Cote, Pierre Cambier, Thierry Arnould, Pierre Van Cutsem, Carine Michiels, Daolin Tang. Heat-Modified Citrus Pectin Induces Apoptosis-Like Cell Death and Autophagy in HepG2 and A549 Cancer Cells. PLOS ONE 2015; 10(3): e0115831 doi: 10.1371/journal.pone.0115831
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Anatole A. Klyosov, Peter G. Traber. Galectins and Disease Implications for Targeted Therapeutics. ACS Symposium Series 2012; 1115: 3 doi: 10.1021/bk-2012-1115.ch001
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Shuangning Du, Yangguang Wang, Wenyang Tao, Shengmin Lu. Differential effects of enzymatically modified Ougan (Citrus Suavissima Hort. ex Tanaka) peel pectins extracted with different methods on inhibiting the proliferation of Hela cells. International Journal of Biological Macromolecules 2024; 278: 134463 doi: 10.1016/j.ijbiomac.2024.134463
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Isaac Eliaz, Avraham Raz. Pleiotropic Effects of Modified Citrus Pectin. Nutrients 2019; 11(11): 2619 doi: 10.3390/nu11112619
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Lucas de Freitas Pedrosa, Avraham Raz, João Paulo Fabi. The Complex Biological Effects of Pectin: Galectin-3 Targeting as Potential Human Health Improvement?. Biomolecules 2022; 12(2): 289 doi: 10.3390/biom12020289
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Sefora Conti, Akiva Vexler, Lior Hagoel, Lital Kalich-Philosoph, Benjamin W. Corn, Nir Honig, Natan Shtraus, Yaron Meir, Ilan Ron, Isaac Eliaz, Shahar Lev-Ari. Modified Citrus Pectin as a Potential Sensitizer for Radiotherapy in Prostate Cancer. Integrative Cancer Therapies 2018; 17(4): 1225 doi: 10.1177/1534735418790382
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Lianzhong Ai, Yun-Chin Chung, Syuan-Yu Lin, Kuan-Ching Lee, Phoency F.-H. Lai, Yongjun Xia, Guangqiang Wang, Steve W. Cui. Active pectin fragments of high in vitro antiproliferation activities toward human colon adenocarcinoma cells: Rhamnogalacturonan II. Food Hydrocolloids 2018; 83: 239 doi: 10.1016/j.foodhyd.2018.05.017
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Mohammed Hussein M. Alsharbaty, Ghassan A. Naji, Sameh S. Ali. Exploring the Synergistic Potential of Pectin-Chitosan Composites for Advanced Drug Delivery and Biomedical Implant Applications: A Comprehensive Review and Future Perspectives. F1000Research 2024; 13: 209 doi: 10.12688/f1000research.145101.1
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Wouter C. Meijers, Rudolf A. de Boer. Galectins and Disease Implications for Targeted Therapeutics. ACS Symposium Series 2012; 1115: 397 doi: 10.1021/bk-2012-1115.ch024
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Victor L. Thijssen, Roy Heusschen, Jo Caers, Arjan W. Griffioen. Galectin expression in cancer diagnosis and prognosis: A systematic review. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2015; 1855(2): 235 doi: 10.1016/j.bbcan.2015.03.003
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Samira Bernardino Ramos do Prado, Gabrielle Fernandez Ferreira, Yosuke Harazono, Tânia Misuzu Shiga, Avraham Raz, Nicholas C. Carpita, João Paulo Fabi. Ripening-induced chemical modifications of papaya pectin inhibit cancer cell proliferation. Scientific Reports 2017; 7(1) doi: 10.1038/s41598-017-16709-3
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