Evaluation of computer aided detection during colonoscopy among Veterans: Randomized clinical trial

Table 1 Patient characteristics, N (%)

	With CADe (N = 124)	Without CADe (N = 120)	P value
Mean age (± SD)	68.7 (7.5)	67.8 (8.0)	0.356
Male sex	118 (95.2)	117 (97.5)	0.333
Mean BMI (± SD)	30.2 (4.7)	30.7 (5.2)a	0.368
Indication
Screening	13 (10.5)	14 (11.7)	0.768
Surveillance	111 (89.5)	106 (88.3)
Race/ethnicity			0.015
Caucasian	69 (55.6)	85 (70.8)
Asian	13 (10.5)	3 (2.5)
African American	18 (14.5)	12 (10.0)
Hispanic	20 (16.1)	12 (10.0)
Other	4 (3.2)	8 (6.7)
Mean BBPS (± SD)	7.9 (1.1)	7.8 (1.1)	0.498

^aData missing for 1 patient.

CADe: Computer aided detection; SD: Standard deviation; BMI: Body mass index; BBPS: Boston Bowel Preparation Score.

Table 2 Procedural characteristics

	With CADe (N = 124)	Without CADe (N = 120)	P value
Number of Polyps Per Colonoscopy, average (± SD)	2.51 (2.35)	3.47 (3.71)	2.976
Number of Adenomas Per Colonoscopy, average (± SD)	1.79 (1.85)	2.53 (3.25)	0.030
Number of Serrated Polyps per Colonoscopy, average (± SD)	0.04 (0.24)	0.13 (0.49)	0.091
Number of Non-adenomatous, non-serrated polyps per colonoscopy, average (± SD)	0.68 (1.06)	0.81 (1.46)	0.426
Adenomatous Polyp Location Distribution Per Colonoscopy, average (± SD)
Proximal Colon, average (± SD)	1.53 (1.72)	2.35 (2.92)	0.009
Distal Colon, average (± SD)	0.82 (1.16)	0.86 (1.33)	0.824
Adenomatous Polyp Size Distribution Per Colonoscopy, average (± SD)
< 6 mm	2.06 (2.03)	2.82 (3.21)	0.029
6-9 mm	0.35 (0.69)	0.53 (0.84)	0.071
≥ 10 mm	0.09 (0.31)	0.13 (0.42)	0.447
Adenomatous Polyp Distribution by Paris Classification Per Colonoscopy, average (± SD)
Is	2.21 (2.25)	3.14 (3.74)	0.020
IIa	0.12 (0.52)	0.18 (0.51)	0.414
Average withdrawal time, mins (± SD)	22.0 (14.8)a	22.5 (11.6)b	0.755
Average procedure time, mins (± SD)	30.7 (16.8)c	32.2 (14.9)a	0.493

^aData missing for 2 patients.

^bData missing for 3 patients.

^cData missing for 1 patients.

CADe: Computer aided detection; SD: Standard deviation.

Table 3 Detection rate of colonoscopies, n/N (%)

	With CADe (N = 124)	Without CADe (N = 120)	P value
Adenoma Detection Rate in All Colonoscopies	85/124 (68.5)	96/120 (80.0)	0.041
Adenoma Detection Rate in Screening Colonoscopies	4/13 (30.8)	6/14 (42.9)	0.516
Adenoma Detection Rate in Surveillance Colonoscopies	81/111 (73.0)	90/106 (84.9)	0.032
Serrated Polyp Detection Rate in All Colonoscopies	4/124 (3.2)	9/120 (7.5)	0.137
Serrated Polyp Detection Rate in Screening Colonoscopies	0/13 (0.0)	1/14 (7.1)	0.326
Serrated Polyp Detection Rate in Surveillance Colonoscopies	4/111 (3.6)	8/106 (7.5)	0.204
Adenomas Per Extraction in All Colonoscopies	222/311 (71.4)	304/416 (73.1)	0.613
Adenomas Per Extraction in Screening Colonoscopies	6/8 (75.0)	18/25 (72.0)	0.868
Adenomas Per Extraction in Surveillance Colonoscopies	216/303 (71.3)	286/391 (73.1)	0.587

CADe: Computer aided detection.

Table 4 Physician specific adenoma detection rate, with or without use of computer aided detection

Physician (#)	ADR with CADe (%)	ADR without CADe (%)	P value
1	19/36 (52.8)	26/35 (74.3)	< 0.0001
2	32/41 (78.0)	33/40 (82.5)	0.615
3	18/27 (66.7)	23/26 (88.5)	0.058
4	16/20 (80.0)	14/19 (73.7)	0.640

ADR: Adenoma detection rate; CADe: Computer aided detection.