Pediatric recurrent Clostridium difficile infections in immunocompetent children: Lessons learned from case reports of the first twelve consecutive patients

Table 1 Patient demographics and final diagnosis

Age of onset (yr)	Gender	# of CDIs	Medications	Co-morbidities	Devices	Prior hosp	Final diagnosis
8.6	F	> 5	PPI, EES, multiple antibiotics course including amoxicillin	DD, BPD	GT	Yes	Eosinophilic colitis
1.17	M	> 5	History of ranitidine, multiple antibiotic courses including amoxicillin	36 wk prematurity, SGA, GERD, cleft lip	GJT	Yes
7	M	> 5	Erythromycin	CP, multiple orthopedic surgeries	GT	Yes	Lactase deficiency
10	F	3	Amoxicillin-clavulanate	None	None	No
3	F	> 5	PPI, multiple antibiotics courses including amoxicillin	DD, renal disease, recurrent pneumonia	GT	Yes
9	M	3	None	ASD	none	No	IBD proctitis
17	M	4	PPI, clindamycin	CP, DD	GT	Yes
12	M	> 5	None	None	None	No	Eosinophilic esophagitis and lactase deficiency
4	F	4	Amoxicillin-clavulanate	History of UTI, hydronephrosis	None	Yes
2	M	4	Amoxicillin	None	None	No	Lactase deficiency
2	M	3	None	None	None	No
14	F	3	Cephalosporin	None	None	Yes

Hosp: Hospitalization; PPI: Proton pump inhibitor; EES: Erythromycin ethylsuccinate; DD: Developmental delay; BPD: Bronchopulmonary dysplasia; SGA: Small for gestational age; GERD: Gastroesophageal reflux disease; CP: Cerebral palsy; ASD: Atrial septal defect; UTI: Urinary tract infection; GT: Gastrostomy tube; GJT: Gastrojejunostomy tube.