Okasha HH, Delsa H, Alsawaf A, Hashim AM, Khattab HM, Abdelfatah D, Abdellatef A, Albitar A. Role of endoscopic ultrasound and endoscopic ultrasound-guided tissue acquisition in diagnosing hepatic focal lesions. World J Methodol 2023; 13(4): 287-295 [PMID: 37771875 DOI: 10.5662/wjm.v13.i4.287]
Corresponding Author of This Article
Hussein Hassan Okasha, MD, Professor, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kasr Al-Aini School of Medicine, Cairo University, Kasr Al-Aini Street, Cairo 11451, Egypt. okasha.hussein@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Prospective Study
Open-Access Policy of This Article
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World J Methodol. Sep 20, 2023; 13(4): 287-295 Published online Sep 20, 2023. doi: 10.5662/wjm.v13.i4.287
Table 1 Cytopathological diagnosis of hepatic focal lesions
Variable
Total, n = 43
n
%
Cytopathological diagnosis
Benign
8
18.60
Malignant
35
81.40
Inflammatory
8
18.60
Cholangitic abscess
6
13.94
Cirrhotic nodule
2
4.65
Primary
6
13.95
Hepatocellular carcinoma
5
11.63
Neuroendocrine tumor
1
2.32
Secondary
29
67.44
Table 2 Endoscopic ultrasonography finding of patients with hepatic focal lesions
Variable
Total, n = 43
No. of passes
1.49 (0.51)
Shortest diameter size in mm
19 ± 12.8/(3-67)
Longest diameter size in mm
26 ± 19.1/(4-109)
Diagnosis
Benign
5 (11.63)
Malignant
38 (88.37)
Table 3 Comparison between endoscopic ultrasonography diagnosis and histopathology results
Variable
EUS, n = 43
Histopathology, n = 43
n
%
n
%
Benign
5
11.63
8
18.60
Malignant
38
88.37
35
81.40
Table 4 Diagnostic utility of elastography in predicting benign and malignant hepatic focal lesions
Elastography, n = 43
n (%)
Benign
Grade 1
0
Grade 2
5 (11.6)
Malignant
38 (88.4)
Grade 3
10 (23.3)
Grade 4
28 (65.1)
Table 5 Comparison between different endoscopic ultrasonography tools regarding their utility in diagnosis of hepatic focal lesions
Tool
Sensitivity
Specificity
PPV
NPV
Overall accuracy
Elastography
97
67
94
80
92
EUS
100
57
94
100
94
FNA/FNB
100
100
100
100
100
Citation: Okasha HH, Delsa H, Alsawaf A, Hashim AM, Khattab HM, Abdelfatah D, Abdellatef A, Albitar A. Role of endoscopic ultrasound and endoscopic ultrasound-guided tissue acquisition in diagnosing hepatic focal lesions. World J Methodol 2023; 13(4): 287-295