Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy

doi:10.5662/wjm.v15.i2.99580

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Jun 20, 2025; 15(2): 99580
Published online Jun 20, 2025. doi: 10.5662/wjm.v15.i2.99580

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Figure 1 Effect of pretreatment on pentylenetetrazol seizure model. A: Latency period for onset of seizures in pentylenetetrazol (PTZ) administered mice (n = 6) (Dunn Post hoc analysis); B: Duration of tonic-clonic convulsions in PTZ induced seizures in mice (n = 6) (Dunn Post hoc analysis); C: Mortality in PTZ induced seizures in mice (n = 6) (Fischer exact test). ^aP value < 0.05 in comparison with control group.

Citation: Tayal V, Mandal A, Haque M I, Mishra A, Kalra BS, Roy V. Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy. World J Methodol 2025; 15(2): 99580
URL: https://www.wjgnet.com/2222-0682/full/v15/i2/99580.htm
DOI: https://dx.doi.org/10.5662/wjm.v15.i2.99580