COVID-19 mutations: An overview

Figure 1 Showing the S protein mediated binding, fusion and various steps of severe acute respiratory syndrome coronavirus-2 infection cycle in the humans. A: Showing the S protein mediated binding and fusion with human cell; B: Showing the various steps in the severe acute respiratory syndrome coronavirus-2 infection cycle in human. It includes viral cellular entry, transcription, replication and packaging, translation, assembly within cellular organelle. SARS-CoV-2: Severe acute respiratory syndrome coronavirus-2; ER: Endoplasmic reticulum; ERCIC: ER-to-Golgi intermediate compartment; RdRP: RNA-dependent RNA polymerase; 3CLpro: 3C-like proteinase; Hel: Helicase.