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For: Abujaber AA, Nashwan AJ. Ethical framework for artificial intelligence in healthcare research: A path to integrity. World J Methodol 2024; 14(3): 94071 [PMID: 39310239 DOI: 10.5662/wjm.v14.i3.94071]
URL: https://www.wjgnet.com/2222-0682/full/v14/i3/94071.htm
Number Citing Articles
1
Augustino Mwogosi, Cesilia Mambile, Nyaura Kibinda, Deo Shao. Blockchain and AI in Tanzanian EHR systems: perceptions, challenges, and solutions. Journal of Systems and Information Technology 2026; 28(1) doi: 10.1108/JSIT-10-2024-0377
2
Amy Wang, Sam Freeman, Farah Magrabi. Governance for safe and responsible AI in healthcare organisations: a scoping review of frameworks. npj Digital Medicine 2026; 9(1) doi: 10.1038/s41746-026-02679-2
3
Senthamil Selvi Poongavanam, C. Thangamani, Karuppiah Nagaraj. Applied Nanobiotechnology for Vector-borne Disease Management: Drug Delivery, Diagnostics, and Sustainable Vector Control. Applied Biochemistry and Biotechnology 2026; 198(5) doi: 10.1007/s12010-026-05662-5
4
Maria Goldberg, Viktor Maria Eisenkolb, Amir Kaywan Aftahy, Chiara Negwer, Hanno S Meyer, Jens Gempt, Bernhard Meyer, Arthur Wagner. Validity of evidence-based recommendations by a large language model for interdisciplinary board decisions in neurooncology: An explorative study and critical evaluation. DIGITAL HEALTH 2025; 11 doi: 10.1177/20552076251384604
5
Nancy Zhang, Rajnish Mohindroo, Praveen Mundlur, Rahul Mittal. Artificial intelligence in primary care: opportunities, risks, and the road ahead. BJGP Open 2025;  doi: 10.3399/BJGPO.2025.0233
6
Abebe Belay Adege, Zhaohui Liang. Advancing Biomedical Engineering With Artificial Intelligence and Machine Learning: A Systematic Review. International Journal of Clinical Practice 2025; 2025(1) doi: 10.1155/ijcp/9888902
7
Raffaele Joseph, Liya Wassie, Hailemichael Getachew, Doris Wangari, Evelyn Gitau, Claude Pirmez, Dominique Laforest, Richa Vashishtha, Ndeya M. Samb, Zoleka Ngcete, Mosoka P. Fallah, Rosa Tsegaye Aga, Michael Mihut, Andreas Alois Reis, Abraham Aseffa, Alemseged Abdissa. Fostering an enabling environment for health AI innovation and scale: The need for tailored ethics training for innovators in low- and middle-income countries. AI and Ethics 2026; 6(1) doi: 10.1007/s43681-025-00921-3
8
Dinargul Mukhammejanova, Assel Mukasheva, Siming Chen. Numerical Study of the Dynamics of Medical Data Security in Information Systems. Computers 2026; 15(1) doi: 10.3390/computers15010037
9
Constantin Pisarenco, Serghei Pisarenco. The three pillars of legal protection for doctors in the era of digital medicine: protocols, documentation, consent. Bulletin of the Academy of Sciences of Moldova. Medical Sciences 2025; 80(3) doi: 10.52692/1857-0011.2024.3-80.12
10
Jaleh Bagheri Hamzyan Olia, Arasu Raman, Chou-Yi Hsu, Ahmad Alkhayyat, Alireza Nourazarian. A comprehensive review of neurotransmitter modulation via artificial intelligence: A new frontier in personalized neurobiochemistry. Computers in Biology and Medicine 2025; 189 doi: 10.1016/j.compbiomed.2025.109984
11
Atul Agrawal, Shikha Verma, Avinash Kumar Sharma, Ashwani Kumar, Mukesh Mann, Pashupati Baniya. Digital Watermarking in Cloud Environments For Copyright Protection. 2025;  doi: 10.4018/979-8-3373-3785-2.ch002
12
Mohammed Alshammari, Mohammed Gronfula. Industry 4.0 - Transforming the Future Beyond Manufacturing - Volume 2, Human-Centred, Organizational and Societal Transformations [Working Title]. 2026;  doi: 10.5772/intechopen.1013167
13
Abdulqadir Nashwan, Jibin Kunjavara. Reimagining Nursing Theories in the Age of Artificial Intelligence: Preserving the Human Essence Amid Digital Transformation. Nursing Inquiry 2026; 33(2) doi: 10.1111/nin.70099
14
Hani Raka Karrar, Mahmoud Ismail Nouh, Maria Talal Kufyah, Amal Mueidh Alshehri, Rahaf Mohammed Zuhair, Ahad Hamdi Alanazi, Faisal Abdulrahman Alahmari, Mohammed Yahya Bakhan Alqarni, Saleh Jabbar Saleh Alzahrani, Amera Gassem Ghzwani, Abdulrahman Olayan Almuqati, Amera Gassem Ghzwani, Muhannad Ibrahim Aldhuwayhi, Turki Othman Ali Alharbi. The Role of Artificial Intelligence in Advancing Hospital Management Information Systems: Review Article. Saudi Journal of Clinical Pharmacy 2025; 4(1) doi: 10.4103/sjcp.sjcp_42_24
15
Rismawati Rismawati, Faradila Hasan, Anny Widiasmara, Muhammad Tahmid Nur, Ramakant Amar Navghare. Harnessing AI for Teacher Support and Professional Development. Advances in Computational Intelligence and Robotics 2025;  doi: 10.4018/979-8-3373-5951-9.ch008
16
Akshata Yashwant Patne, Meghraj Suryawanshic. Artificial Intelligence in Patient Counselling. 2026;  doi: 10.1016/B978-0-443-43823-3.00011-X
17
Ajagbe Kamil Adeniran, Emmanuel Oyedeji Oyetola, Habiblah Ayomide Jagunmolu, Rebecca Opeyemi Adeyemo, Saheed Olamide Salami, Olaniyi Taofeek Oyetola, Samuel Oyeponle Oyelude, Precious Adegbosin, Toluwanimi Oladele Idowu, Oluwadamilare Okikijesu Ezekiel, Daniel Ayanleke. The Role of Point-of-Care Ultrasound (POCUS) Powered by Artificial Intelligence in Trauma and Cardiac Arrest Assessment: A Narrative Review. SN Comprehensive Clinical Medicine 2026; 8(1) doi: 10.1007/s42399-026-02315-w
18
Pegah Ahadian, Wei Xu, Dongfang Liu, Qiang Guan. Ethics of trustworthy AI in healthcare: Challenges, principles, and practical pathways. Neurocomputing 2026; 661 doi: 10.1016/j.neucom.2025.131942
19
Ion Nemteanu, Adir Mancebo Jr, Leslie Joe, Ryan Lopez, Patricia Lopez, Warren Woodrich Pettine. Scalable Agile Framework for Execution in AI for Medical AI Ethics Policy Design in Small- and Medium-Sized Enterprises. Journal of Medical Internet Research 2026; 28 doi: 10.2196/80028
20
Muhammad Agreindra Helmiawan, Sri Bekti Handayani Ningsih, Iyat Ratna Komala, Mona Yulianti, Uu Sunarya, Balkis Fitriani Faozi. Evaluation of Healthcare Professionals' Satisfaction with the Use of AI in Supporting Clinical Diagnosis. 2025 13th International Conference on Cyber and IT Service Management (CITSM) 2025;  doi: 10.1109/CITSM67730.2025.11291220
21
Sun Young Choo, Kimberley T. Jackson, Richard G. Booth, Foroozan Atashzadeh-Shoorideh. Defining Ethical AI in Nursing: A Concept Analysis Grounded in Accountability, Explainability, Privacy, and Justice. Nursing Forum 2026; 2026(1) doi: 10.1155/nuf/9348533
22
Ivy Payne Nkrumah, Felicia Engmann, Kofi Sarpong Adu-Manu. Ethical AI in Healthcare: A Comprehensive Review Addressing Privacy, Security, and Fairness. ETHICS IN PROGRESS 2025; 16(2) doi: 10.14746/eip.2025.2.2
23
Itamar Ben Shitrit, Daphna Idan, Mark Volevich, Hadar Sharabi Goldenberg, Dolev Vaknin, Or Degany, Nitzan Abelson, Yair Binyamin, Raouf Nassar, Majd Nassar, Aviya Kedmi, Alexander Zlotnik, Sharon Einav, Xiangbin Meng. Real World Human-LLM Interactions – Prospective blinded versus unblinded expert physician assessments of LLM responses to complex medical dilemmas. PLOS Digital Health 2026; 5(3) doi: 10.1371/journal.pdig.0001278
24
The Cuong Nguyen. Artificial Intelligence (AI) and Youth Mental Health. Child & Youth Services 2026;  doi: 10.1080/0145935X.2026.2725208
25
Sylvain L. B. Faye, Fatoumata B. Diongue, Abdourakhmane Ndao, Boly Diop, Georgette H. C. Sow, Ndiaye Dia, Fallou Diakhate, Tidiane Gadiaga, Pape Samba Dieye, Oumou Kalsom D. Gueye, Yoro Sall, Ibrahima Seck, Youssou Bamar Gueye, Aminata Massaly, Moussa Seydi, Ibrahima Sy. Advancing epidemic intelligence: evaluating Senegal’s mpox surveillance system and readiness for AI-driven predictive modelling. Frontiers in Public Health 2026; 14 doi: 10.3389/fpubh.2026.1742888
26
Vasileios Leivaditis, Vasiliki Androutsopoulou, Ioannis Panagiotopoulos, Andreas Antonios Maniatopoulos, Elias Liolis, Konstantinos Tasios, Konstantinos Nikolakopoulos, Chrysa Andrikopoulou, Theodora Skoura, Andreas Antzoulas, Dimitrios Litsas, Anastasios Sepetis, Francesk Mulita. Calculated courage: risk, responsibility, and the ethos of cardiac surgery in the age of artificial intelligence. Archives of Medical Science – Atherosclerotic Diseases 2026; 11(1) doi: 10.5114/amsad/220586
27
Jeffrey Rakover, Marina Lynne Renton, Pierre Barker, Gareth Kantor. Advancing AI in healthcare: three strategic roles for quality and safety leaders. BMJ Quality & Safety 2026; 35(3) doi: 10.1136/bmjqs-2025-019050
28
Giovannino Silvestri, Aditi Chatterjee. HIV-1 and Artificial Intelligence: From Molecular Insight to Population Impact. Journal of AIDS and HIV Treatment 2025;  doi: 10.33696/AIDS.7.068
29
Venkata Manikesh Iruku. LLM-Powered Self-Auditing Framework for Healthcare Data Pipelines: Continuous Validation Lifecycle. European Journal of Computer Science and Information Technology 2025; 13(50) doi: 10.37745/ejcsit.2013/vol13n5082100
30
Rachel Wolpert, Sook-Lei Liew, Kristen Pickett, Chao-Yi Wu. Invited Commentary: Transforming Occupational Therapy Research With Artificial Intelligence. OTJR: Occupational Therapy Journal of Research 2026;  doi: 10.1177/15394492261464096
31
Aishi Huang. Ethical Dimensions of Artificial Intelligence in Personalized Medicine: Navigating Challenges and Shaping Future Policies. 2025 IEEE 49th Annual Computers, Software, and Applications Conference (COMPSAC) 2025;  doi: 10.1109/COMPSAC65507.2025.00117
32
Shashwata Sahu, Navonita Mallick, Ramesh Chandra Sethi, Prativa Panda. Smart Hospital Anatomy with Advanced Sensors. 2026;  doi: 10.1016/B978-0-443-45875-0.00028-4
33
Sacramento Pinazo-Hernandis, Rosa Redolat, Antonio Caballer, Patricia C Heyn. Artificial intelligence-based technologies to reduce loneliness and improve social connectedness in older people: a systematic review. The Gerontologist 2026; 66(1) doi: 10.1093/geront/gnaf267
34
Francis Mungai Kaburu, Ping Zhu, Abdulswabul Kudiza, Dean McDonnell, Claudimar Pereira da Veiga, Jing-Bao Nie, Yu-Tao Xiang, Zhaohui Su. AI for mental disorders and diabetes comorbidity management: A scoping review. General Hospital Psychiatry 2026; 102 doi: 10.1016/j.genhosppsych.2026.06.009
35
Matthew Halton. Finding Balance: Ethical Promotion of Artificial Intelligence Use to Youth in an Age of Loneliness. Child & Youth Services 2025;  doi: 10.1080/0145935X.2025.2561693
36
Anandhavalli Muniasamy, Gauthaman Karunakaran. Integrative Machine Learning and Optimization Algorithms for Disease Prediction. 2025;  doi: 10.4018/979-8-3373-1087-9.ch012
37
Sayed Ibrahim Ali, Mostafa Shaban. Nursing Academic Reviewers’ Perspectives on AI‐Assisted Peer Review: Ethical Challenges and Acceptance. International Nursing Review 2025; 72(3) doi: 10.1111/inr.70100
38
Junying Jiang, Lúcia Domingues, Jorge M. Mendes. Synthetic data in medical imaging within the EHDS: a path forward for ethics, regulation, and standards. Frontiers in Digital Health 2025; 7 doi: 10.3389/fdgth.2025.1620270
39
Tulay Yazici. Navigating Modern Digital Communication Ethics and Law. 2025;  doi: 10.4018/979-8-3373-1702-1.ch002
40
Andrew Prahl. The AI-Reflexivity Checklist (ARC): A Pre-Analysis Pause for LLM-Assisted Coding. Qualitative Health Research 2026; 36(2-3) doi: 10.1177/10497323251401503
41
Fear of the future: Understanding artificial intelligence phobia and its socio-cultural implications. International Journal of ADVANCED AND APPLIED SCIENCES 2026; 13(2) doi: 10.21833/ijaas.2026.02.014
42
Diego Fernando Garcia-Bañol, Adrianny Mahelis Arias-Choles, Silvia Aldana-Peréz, Gustavo J. Aroca-Martínez, Carlos Guido Musso, Roberto Navarro-Quiroz, Alex Dominguez-Vargas, Henry J. Gonzalez-Torres. Machine learning in lupus nephritis: bridging prediction models and clinical decision-making towards personalized nephrology. Frontiers in Medicine 2025; 12 doi: 10.3389/fmed.2025.1686057
43
Kyle Sporn, Rahul Kumar, Phani Paladugu, Joshua Ong, Tejas Sekhar, Swapna Vaja, Tamer Hage, Ethan Waisberg, Chirag Gowda, Ram Jagadeesan, Nasif Zaman, Alireza Tavakkoli. Artificial Intelligence in Orthopedic Medical Education: A Comprehensive Review of Emerging Technologies and Their Applications. International Medical Education 2025; 4(2) doi: 10.3390/ime4020014
44
Salah A. Alshehade, Raghdaa Hamdan Al Zarzour, Ahmad Naoras Bitar, Abdul Razzak Alshehadeh, Surtika Tamilwanan, Safni Safni. Artificial Intelligence in Business. Lecture Notes in Networks and Systems 2026; 1503 doi: 10.1007/978-3-031-96631-6_32
45
Armin Ahmadi, Vineetha Menon, Gregory H. Grossman, Jerome Baudry, Daniel Adamek. BEACON: An Artificial Intelligence–Powered Optimized Biobank Sample Management System Leveraging Real-World Data. Biopreservation and Biobanking 2026; 24(3) doi: 10.1177/19475535251369692
46
Sangita Roy, Nabanita Roy. Responsible AI. 2026;  doi: 10.1002/9781394355471.ch11
47
Abdulqadir J Nashwan, Ahmad A Abujaber. Developing predictive models in nursing research and clinical practice. Evidence Based Nursing 2026; 29(4) doi: 10.1136/ebnurs-2025-104474
48
Rismawati Rismawati, Muhammad Tahmid Nur, Rustan Santaria, Supriadi Supriadi, Andi Subhan Amir. Leveraging LLMs for Business Innovation. 2026;  doi: 10.4018/979-8-3373-3912-2.ch011
49
Virendra S. Gomase, Arjun P. Ghatule, Rupali Sharma, Satish Sardana. Cybersecurity and Compliance in Clinical Trials: The Role of Artificial Intelligence in Secure Healthcare Management. Reviews on Recent Clinical Trials 2025; 20(4) doi: 10.2174/0115748871366467250413070850
50
Kexin Zhao, Ningning Wang, Zhicai Xie. The digital transformation of clinical teaching: a review of AI and data-driven quality assurance systems in medical education. Frontiers in Public Health 2026; 14 doi: 10.3389/fpubh.2026.1915158
51
Lazaro Amon Solomon Haule, Doreen Mloka, Muhsin Aboud. Exploring the operational challenges of navigating ethical oversight in the era of artificial intelligence: a qualitative study of health research ethics committees in Tanzania. BMC Medical Ethics 2026; 27(1) doi: 10.1186/s12910-026-01541-0
52
Chandrabose Selvaraj, Deepali Desai. . Advances in Protein Chemistry and Structural Biology 2026;  doi: 10.1016/bs.apcsb.2026.06.010
53
Francisco Epelde. Revolutionizing Patient Safety: The Economic and Clinical Impact of Artificial Intelligence in Hospitals. Hospitals 2024; 1(2) doi: 10.3390/hospitals1020015
54
Suriyaraj Shanmugam Prema, Dhanraj Ganapathy, Deepankumar Shanmugamprema. AI‐Driven Epidemiology: The Next Frontier in Precision Public Health. WIREs Data Mining and Knowledge Discovery 2026; 16(2) doi: 10.1002/widm.70077
55
Heisook Lee, Sejung Yang, Yusung Chu. Sex, Gender, and Emerging Technology in Healthcare: Mitigating Bias and Fostering Equity. 2026;  doi: 10.1007/978-981-95-2070-1_10
56
Sulistyo Heripracoyo. Implementing Artificial Intelligence in the Tourism Industry: A Framework. 2025 International Conference on Information Management and Technology (ICIMTech) 2025;  doi: 10.1109/ICIMTech67074.2025.11265698
57
Gerry Firmansyah, Brij B. Gupta, Mosiur Rahaman, Yogita Abichandani. Combatting Digital Arrest Fraud and Identity Theft With AI and Decision Support Systems. Advances in Computational Intelligence and Robotics 2026;  doi: 10.4018/979-8-3373-4149-1.ch006
58
Kalpana Singh, Abdulqadir J. Nashwan. Artificial Intelligence-driven solutions: revolutionizing patient care in multimorbidity management. Discover Health Systems 2025; 4(1) doi: 10.1007/s44250-025-00251-5
59
Teresa Sides, Dhouha Kbaier, Tracie Farrell, Aisling Third. Bridging trust gaps: Stakeholder perspectives on AI adoption in the United Kingdom NHS primary care. DIGITAL HEALTH 2025; 11 doi: 10.1177/20552076251386706
60
Ahmad A Abujaber, Abdulqadir J Nashwan. Harnessing artificial intelligence for suicidality detection. Evidence Based Nursing 2026; 29(3) doi: 10.1136/ebnurs-2025-104277
61
Olatunde Ayomide Olasehan. Threat Intelligence and Cloud Trust Models for Healthcare Security. 2025;  doi: 10.4018/979-8-3373-4918-3.ch003
62
Moustafa Mohamed Hassan. Revolutionizing Healthcare Experience With Digital Medical Tourism. Advances in Healthcare Information Systems and Administration 2025;  doi: 10.4018/979-8-3693-7888-5.ch016
63
Donald C. Wunsch III, Daniel B. Hier. Large language models for neurology: a mini review. Frontiers in Digital Health 2026; 7 doi: 10.3389/fdgth.2025.1732759
64
Imane Ihaddouchen, Stefan Buijsman, Giorgia Pozzi, Davy van de Sande, Andreas Alois Reis, Reggie Townsend, Jeroen van den Hoven, Diederik Gommers, Michel E van Genderen. Responsible artificial intelligence in healthcare: a systematic review on the use of ethical principles in the development and deployment of artificial intelligence. BMJ Digital Health & AI 2025; 1(1) doi: 10.1136/bmjdhai-2025-000086
65
Generative AI in Healthcare: Concepts, Methodologies, Tools, and Applications. Studies in Computational Intelligence 2025; 1234 doi: 10.1007/978-981-95-2129-6_6
66
Tigest Tamrat, Rohit Malpani, Sara Mengistu, Anja Kovacs, Yu Zhao, Anuj Kapilashrami, Allan Maleche, Sameer Pujari, Andreas Reis, Lale Say. Beyond no harm: Advancing research on artificial intelligence for sexual and reproductive health and rights. npj Women's Health 2025; 3(1) doi: 10.1038/s44294-025-00113-8
67
Tirath Patel, Hamza Yousuf Ibrahim, Fathimathul Henna, Fatima Nasir, Abbas Hussain, Rahma Naveed, Aziz Ur Rehman, Syeda Ramish Zehra Kazmi, Bhumi Daishik Patel, Nikhilesh Anand, Richard M. Millis. A narrative review on artificial intelligence in neurosurgery: ethical challenges and implementation considerations. Annals of Medicine & Surgery 2025; 87(12) doi: 10.1097/MS9.0000000000004246
68
Hsueh-Wen Wang, Christopher Fong, Daphne Cormier Picq, Shilpi Tripathi. Transforming Mental Health Care: An Integrative Review on Integrating Psychotherapy, Artificial Intelligence, and Kinesiology. Open Journal of Medical Psychology 2025; 14(04) doi: 10.4236/ojmp.2025.144011
69
Baburao Chirra, D. Rajyalakshmi, M. Pavana Lalitha, Harani Bontha. Harnessing Artificial Intelligence to Ensure Diverse Global Teams. 2026;  doi: 10.1016/B978-0-443-34135-9.00012-X
70
Shivali Rahi, Viney Lather, Arpana Rana, Jayamanti Pandit. Comprehensive Framework for the Global Regulation and Approval of AI-Integrated Medical Devices. Applied Drug Research, Clinical Trials and Regulatory Affairs 2025; 11 doi: 10.2174/0126673371347630250418134235
71
Stanley Lyndon. Moving beyond diagnostic labels in psychiatry: outcome‐linked treatment modelling. General Psychiatry 2025; 38(6) doi: 10.1136/gpsych-2025-102436
72
Piyush Amol Bhosale, Shravani Kulkarni, Amna Kausar, Aditya Shrivastav, Susanta Das. Advanced AI and Prompt Engineering Techniques and Resources. Advances in Computational Intelligence and Robotics 2025;  doi: 10.4018/979-8-3373-0250-8.ch006
73
Ahmad A Abujaber, Abdulqadir J Nashwan. Artificial intelligence integration in critical care nursing. Evidence Based Nursing 2026; 29(2) doi: 10.1136/ebnurs-2024-104249
74
Anirudh Dwajan, Deepak Ranjan Patro, Amber Agarwal, Mary Lalhmingmawii. Artificial intelligence in orthopaedics: Clinical decision support, medical imaging, surgical planning, and outcome prediction. World Journal of Clinical Cases 2026; 14(17): 120192 doi: 10.12998/wjcc.v14.i17.120192
75
Geetha Manoharan, M. Nivedha. AI-Powered Developments in Medical Robotics. 2026;  doi: 10.1016/B978-0-443-27783-2.00002-8
76
Santiago Frid, Octavi Bassegoda, Maria Araceli Camacho Mahamud, Gemma Sanjuan, Miguel Ángel Armengol de la Hoz, Leo Celi, Isaac Cano Franco, Gerard Anmella, Tomas Cuñat López, Ana Lucía Arellano, Lina María Leguízamo-Martínez, Laura Mezquita, Petter Axcell Peñafiel Macías, Antonio Gallardo-Pizarro, Ruben González Colom, Arturo Renú Jornet, Guillem Bracons Cucó, Xavier Borrat Frigola. Bridging generative AI and healthcare practice: insights from the GenAI Health Hackathon at Hospital Clínic de Barcelona. BMJ Health & Care Informatics 2025; 32(1) doi: 10.1136/bmjhci-2025-101640
77
Andi Asrifan, Rismawati Rismawati. Modernizing Public Administration With New Digital Advancements. 2025;  doi: 10.4018/979-8-3373-1484-6.ch003
78
Gerald C. Imaezue, David Ajayi, Celine Davis. Treatment of aphasia in linguistically diverse populations: current and future directions. Frontiers in Psychology 2025; 16 doi: 10.3389/fpsyg.2025.1612413
79
Raja Ahmed, Suraiya Akhtar, Ankur Das, Khaleda Begum, Abhijit Sarma, Amartya Chakraborty, Tanisha Neog, Sofia Banu. Revolutionizing Drug Development. 2026;  doi: 10.1016/B978-0-443-34059-8.00010-5
80
Ricardo Ramírez-Barrantes, Steven S. Gouveia, Claudio Córdova. The Palgrave Handbook on the Ethics of Artificial Intelligence. 2026;  doi: 10.1007/978-3-032-15112-4_30