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©2014 Baishideng Publishing Group Inc.
World J Transl Med. Dec 12, 2014; 3(3): 119-132
Published online Dec 12, 2014. doi: 10.5528/wjtm.v3.i3.119
Published online Dec 12, 2014. doi: 10.5528/wjtm.v3.i3.119
Figure 1 Obesity related diseases.
T2DM: Type 2 diabetes mellitus; NASH: Non-alcoholic steatosis hepatis.
Figure 2 Bariatric surgical procedures.
A: Roux-Y gastric bypass; B: Sleeve gastrectomy; C: Biliopancreatic diversion with duodenal switch; D: Gastric band.
Figure 3 Endocrine, inflammatory, and cancer promoting effects of adipose tissue.
IL-8: Interleukin 8; PGE2: Prostaglandin E2; TNF-α: Tumor necrosis factor-α; MCP-1: Monocyte chemoattractant protein-1; STAT3: Signal transducer and activator of transcription 3; PI3K: Phosphatidylinositol-4,5-bisphosphate 3-kinase; MAPK: Mitogen-activated proteinkinase; NF-κB: Nuclear-factor-kappa-light-chain-enhancer activated B cells; IGF-1: Insulin-growth factor-1; AMPK: 5’AMP-activated protein kinase; mTOR: Mechanistic target of rapamycin.
- Citation: El Gammal AT, Dupree A, Wolter S, Aberle J, Izbicki JR, Güngör C, Mann O. Obesity research: Status quo and future outlooks. World J Transl Med 2014; 3(3): 119-132
- URL: https://www.wjgnet.com/2220-6132/full/v3/i3/119.htm
- DOI: https://dx.doi.org/10.5528/wjtm.v3.i3.119