Atypical hemolytic-uremic syndrome due to complement factor I mutation

Table 1 Laboratory investigations

Laboratory parameter	Before admission (Nov 25, 2012)	Day of admission (Nov 28, 2012)
Hematologic tests
Complete blood count
WBCs (normal, 4-10 × 109/L)	14.4	14.1
Hemoglobin (normal, 12-15 g/dL)	11.8	8.9
Platelets (normal, 150-400 × 109/L)	399	103
Coagulation profile (s)
PT (normal, 11-14)	12	10
INR (normal, 0.9-1.2)	0.9	0.9
PTT (normal, 20-40)	24	29
Schistocytes on peripheral blood film	Not done	Yes
Serum biochemical tests
Renal function tests (mmol/L)
Sodium (normal, 135-145)	142	129
Potassium (normal, 3.5-5.5)	3.9	4.1
Bicarbonate (normal, 22-28)	15	11
Chloride (98-106)	110	99
Urea (normal, 2.1-7.1)	3.2	19
Creatinine (normal, 62-106)	54	773
Liver function tests
Total bilirubin (normal, 5-20 mmol/L)	17.1	25.8
AST (normal, 0-40 U/L)	17	142
ALT (normal, 0-30 U/L)	18	240
ALP (normal, 40-129 U/L)	104	90
GGT (normal, 8-65 U/L)	21	18
Albumin (normal, 35-50 g/L)	42	29
LDH (normal, 140-280 U/L)	273	3377

PT: Prothrombin time; INR: International normalized ratio; PTT: Partial thromboplastin time; AST: Aspartate transaminase; ALT: Alanine transaminase; ALP: Alkaline phosphatase; GGT: γ-Glutamyltransferase; LDH: Lactate dehydrogenase.