Immunohistochemical expression of intrarenal renin angiotensin system components in response to tempol in rats fed a high salt diet

Table 1 High-salt diet increased mean arterial pressure, urinary sodium excretion and sodium fractional excretion (%), but did not alter glomerular filtration rate, respect to normal salt fed animals

	NS	NS-T	HS	HS-T
MAP (mmHg)	92 ± 3	94 ± 3	108 ± 3a	95 ± 2c
GFR (mL/min)	1.50 ± 0.1	3.2 ± 0.5c	1.52 ± 0.2	3.1 ± 0.6c
UVNa (μmol/min per kilogram)	0.25 ± 0.1	2.03 ± 0.90c	3.56 ± 0.70a	13.2 ± 1.2ac
FENa (%)	0.06 ± 0.02	0.10 ± 0.06	0.50 ± 0.08a	1.20 ± 0.15ac

All values are mean ± SEM (n = 5-6 per group),

^aP < 0.05 vs respective NS group,

^cP < 0.05 vs respective group without tempol. NS: Normal salt diet group; HS: High salt diet group; NS-T: Normal salt diet plus tempol group; HS-T: High salt diet plus tempol group; MAP: Mean arterial pressure; GFR: Glomerular filtration rate; UV_Na: Urinary sodium excretion; FE_Na: Fractional sodium excretion.