Prolonged hypernatremia triggered by hyperglycemic hyperosmolar state with coma: A case report

Table 1 Serum chemistries and calculated values related to tonicity

Time	[Glu]	[Na]	Tonicity	[Na]Corrected
	mg/dL	mmol/L	mOsm/L	mmol/L
-15 to -2 yr1a	99.6 ± 22.0	141.1 ± 2.7	287.6 ± 5.6	141.0 ± 2.7
-21 d1	235	139	291.1	141.6
-14 d1	304	141	298.9	144.3
-3 d1	809	135	314.9	146.3
Admission	1236	168	404.7	186.2
+2 h2	1141	169	401.4	185.7
+4 h2	982	170	394.6	184.1
+10 h2	771	165	372.8	175.7
+14 h2	650	163	362.1	171.8
+18 h2	611	160	353.9	168.2
+22 h2	548	165	360.4	172.2
+24-48 h2	233.5 ± 151.7	164.0 ± 1.9	341.0 ± 9.7	166.0 ± 3.3
+48-72 h2	176.6 ± 72.3	168.0 ± 1.9	345.8 ± 7.6	169.2 ± 3.0
+72-96 h2	151.8 ± 23.0	165.3 ± 2.6	338.9 ± 4.7	166.1 ± 2.1
+96-120 h2	185.0 ± 99.0	176.5 ± 2.1	363.3 ± 1.3	177.9 ± 0.5
+120-144 h2	131	172	351.3	172.5
+144-168 h2	135	157	321.5	157.6
+168-192 h2	186.5 ± 139.3	158.0 ± 9.9	326.4 ± 27.5	159.4 ± 12.2
+9-14 d2	175.5 ± 53.7	146.8 ± 1.8	303.5 ± 4.4	147.9 ± 1.8
+14-21 d2	241.3 ± 55.6	143.0 ± 3.9	299.4 ± 7.0	145.2 ± 3.7
+3 mo2	240	155	323.3	157.2

¹Time before admission;

²Time after onset of treatment;

^aPeriod of lithium intake; [Glu]: Serum glucose concentration; [Na]: Serum sodium concentration; [Na]_Corrected: Serum sodium concentration corrected to a serum glucose level of 100 mg/dL; Values reported as mean ± SD represent 2-22 measurements.