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Feb 6, 2015 (publication date) through Nov 4, 2025
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World Journal of Nephrology
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2220-6124
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright ©The Author(s) 2015.
World J Nephrol. Feb 6, 2015; 4(1): 19-30
Published online Feb 6, 2015. doi: 10.5527/wjn.v4.i1.19
Table 1 Events common to aging and uremia covered by this review
AgingUremia
TGF-β↑TGF-β↑
Autophagy ↓Autophagy ↓
Apoptosis ↑ (muscle)Apoptosis ↑
Senescence ↑Senescence ↑
Telomere shortening ↑Telomere shortening ↑
Stem cell exhaustion ↑Stem cell exhaustion ↑
Klotho ↓Klotho ↓
AGEs ↑AGEs ↑
Mitochondrial dysfunction ↑Mitochondrial dysfunction ↑
TGF-β: Transforming growth factor beta; AGEs: Advanced glycation end products.
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