Curcumin attenuates high glucose-induced apoptosis in renal tubular epithelial cells by enhancing the Nrf2/heme oxygenase-1 antioxidant pathway

doi:10.5527/wjn.119984

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 119984
Published online Sep 25, 2026. doi: 10.5527/wjn.119984

Table 1 Primer sequences used for quantitative polymerase chain reaction

Gene	Primer direction	Sequence (5′-3′)	Product size
GAPDH	Forward	ACAGCAACAGGGTGGTGGAC	253 bp
	Reverse	TTTGAGGGTGCAGCGAACTT
NRF2	Forward	TGACTCTGACTCCGGCATTT	188 bp
	Reverse	CCCAGAAGAATGTGTTGGC
HO-1	Forward	GCATGTCCCAGGATTTGTCC	192 bp
	Reverse	GGTTCTGCTTGTTTCGCTCT
Bax	Forward	AAGAAGCTGAGCGAGTGTCT	153 bp
	Reverse	CCAGTTGAAGTTGCCGTCTG
Bcl-2	Forward	GCCTTCTTTGAGTTCGGTGG	221 bp
	Reverse	CTGAGCAGCGTCTTCAGAGA

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Citation: Li Y, Wang LL, Yu XZ, Xie S, Li PF, Huang Y, Bao PL. Curcumin attenuates high glucose-induced apoptosis in renal tubular epithelial cells by enhancing the Nrf2/heme oxygenase-1 antioxidant pathway. World J Nephrol 2026; 15(3): 119984
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/119984.htm
DOI: https://dx.doi.org/10.5527/wjn.119984

Li Y, Wang LL, Yu XZ, Xie S, Li PF, Huang Y, Bao PL. Curcumin attenuates high glucose-induced apoptosis in renal tubular epithelial cells by enhancing the Nrf2/heme oxygenase-1 antioxidant pathway. World J Nephrol 2026; 15(3): 119984 [DOI: 10.5527/wjn.119984]

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