Conversion from calcineurin inhibitors to mTOR inhibitors stabilizes diabetic and hypertensive nephropathy after liver transplant

Table 1 Features of patients converted to mammalian target of rapamycin inhibitors

Variable	DM (28)	HT (27)	Prot (27)	DM + HT + prot (8)	P-value
Age (yr)	54.3	55.1	54.8	55.2	0.61
Male	21	23	22	7	0.43
DM prior to OLT	28	8	8	8	0.52
Hypertension prior to OLT	5	19	5	5	0.34
Proteinuria prior to OLT	7	6	19	6	0.42
Etiology of liver disease
Hepatitis C	11	11	10	3	0.32
Alcohol	14	13	13	4	0.67
Other	3	3	4	1	0.56
Hepatocellular carcinoma	6	5	5	1	0.48
Initial creatinine	1.31	1.48	1.44	1.35	0.23

DM: Diabetes mellitus; HT: Hypertension; Prot: Proteinuria; OLT: Orthotopic liver transplant.